Unexpected presentation of accessory breast cancer presenting as a subcutaneous mass at costal ridge: a case report
ConclusionsThis patient was diagnosed as having accessory breast cancer which presented with a subcutaneous mass. As this condition is exceptionally rare but curable by early treatments, we recommend surgeons to consider potential malignancy when patients present with a subcutaneous mass. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - March 31, 2020 Category: General Medicine Source Type: research

Metastatic malignant melanoma with neuroendocrine differentiation: a case report and review of the literature
ConclusionsMalignant melanoma may display neuroendocrine differentiation, and the entity should be considered a rare differential diagnosis when assessing biopsies of suspected neuroendocrine carcinomas. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - March 31, 2020 Category: General Medicine Source Type: research

Pralatrexate as a bridge to allogeneic hematopoietic stem cell transplantation in a patient with advanced-stage extranodal nasal-type natural killer/T cell lymphoma refractory to first-line chemotherapy: a case report
ConclusionsThis is the first study to present pralatrexate as a successful bridge to allogeneic hematopoietic stem cell transplantation in a  29-year-old Asian male patient with advanced-stage extranodal natural killer/T cell lymphoma refractory to first-line dexamethasone, methotrexate, ifosfamide, L-asparaginase, and etoposide chemotherapy. This case provides a novel treatment opinion for extranodal natural killer/T cell lymphoma, esp ecially for the Far East Asian population. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - March 17, 2020 Category: General Medicine Source Type: research

Correction to: Atrial myxoma with cerebellar signs: a case report
In the publication of this article [1], there is an error in the name of one of the contributing authors. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - March 17, 2020 Category: General Medicine Source Type: research

Primary neuroendocrine tumors of the breast: two case reports  and review of the literature
ConclusionDue to the rarity of primary breast neuroendocrine tumors, no standard therapy exists and the prognosis remains difficult to determine. Studies, including larger series, are needed in order to understand the biological behavior of these tumors. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - March 10, 2020 Category: General Medicine Source Type: research

Emergency laparoscopic repair of coitus-induced vaginal cuff dehiscence: a case report
ConclusionLaparoscopic repair is a safe treatment option to manage vaginal cuff dehiscence after total hysterectomy. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - March 9, 2020 Category: General Medicine Source Type: research

Rapid cognitive decline in a patient with chronic lymphocytic leukaemia: a case report
ConclusionPML remains a rare complication of ofatumumab treatment. Nevertheless, clinicians should maintain a certain level of suspicion for this risk, especially in the context of patients presenting with clinical syndromes of encephalopathy and focal neurologic deficits. Furthermore, research to better our understanding of the manifold links between B-cell function and JCV regulation could provide valuable information for use in the future prevention and treatment of PML. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - March 3, 2020 Category: General Medicine Source Type: research

Hoffmann ’s syndrome necessitating forearm fasciotomy: a case report
ConclusionHoffmann ’s syndrome may precipitate a compartment syndrome in the absence of trauma. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - March 2, 2020 Category: General Medicine Source Type: research

Cold beverage-induced vasovagal syncope in a healthy young adult man: a case report
ConclusionsThe suddenness and unpredictability of swallowing-induced syncope make it a potentially dangerous condition, with risks both to the patient as well as, depending on the context, others. However, it is poorly understood due to its infrequency. The present case report adds to the body of much needed evidence which should help facilitate an improved understanding of the phenomenon. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - February 28, 2020 Category: General Medicine Source Type: research

Metastatic renal cell carcinoma to the pancreas and subcutaneous tissue 10  years after radical nephrectomy: a case report
ConclusionSynchronous metastatic renal cell carcinoma to the pancreas and subcutaneous tissue is very rare, and it might occur after primary tumor resection. Patients must undergo lifelong monitoring and follow-up with regular examination so that any possible metastasis can be detected early. The optimal resection strategy should involve adequate resection margins and maximal tissue preservation of the pancreas, because renal cell carcinoma metastasizing to the pancreas and subcutaneous tissue has a good prognosis with long-term survival. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - February 26, 2020 Category: General Medicine Source Type: research

Management of psoriasis-like rash associated with idelalisib monotherapy in a patient with refractory follicular lymphoma: a  case report
ConclusionsThe clinical relevance of the effective management of adverse events in this case demonstrates the opportunity to enable patients to remain on therapy, thereby maintaining long-term response and improving overall outcomes. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - February 24, 2020 Category: General Medicine Source Type: research

Acromegaly with congenital generalized lipodystrophy – two rare insulin resistance conditions in one patient: a case report
AbstractBackgroundLipodystrophies are a group of diseases which are characterized by abnormal adipose tissue deposition and are frequently associated with metabolic changes. Congenital generalized lipodystrophy is an autosomal recessive syndrome, with a prevalence
Source: Journal of Medical Case Reports - February 21, 2020 Category: General Medicine Source Type: research

Primary aldosteronism concurrent with subclinical Cushing ’s syndrome: a case report and review of the literature
ConclusionsWe suggest that patients with primary aldosteronism should have a low-dose overnight dexamethasone suppression test to screen for hypercortisolism. It can help avoid misdiagnoses and contribute to proper understanding of the adrenal vein sampling result. Making sure of the nidus of aldosterone and cortisol secretion is crucial for the therapy of patients with primary aldosteronism and subclinical Cushing ’s syndrome. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - February 20, 2020 Category: General Medicine Source Type: research

Unusual recurrent metastasizing benign breast papilloma: a case report
ConclusionsWe present an unusual case of multiple recurrent peripheral papillomas with entirely benign histologic features exhibiting malignant behavior over a protracted period of many years, with an invasion of pectoralis musculature and possibly internal mammary and mediastinal nodes. Her treatment course included multiple surgeries (ultimately mastectomy), radiation therapy, and endocrine therapy. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - February 19, 2020 Category: General Medicine Source Type: research

Miller Fisher syndrome with bilateral vocal cord paralysis: a case report
ConclusionThe occurrence of acute or subacute descending paralysis with involvement of bulbar muscles and respiratory failure can often divert clinicians to a diagnosis of neuromuscular junction disorders (such as botulism or myasthenia gravis), vascular causes like stroke, or electrolyte and metabolic abnormalities. Early identification of Miller Fisher syndrome with appropriate testing is essential to prompt treatment and prevention of further, potentially fatal, deterioration. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - February 18, 2020 Category: General Medicine Source Type: research

Diagnostically challenging human papillomavirus-associated primary squamous cell carcinoma of the rectum with metastasis in both ovaries: a case report
ConclusionColorectal squamous cell carcinoma is a rare disease. In cases of colorectal squamous cell carcinoma, metastatic disease at any other location has to be excluded. Human papillomavirus genotyping is essential in this context. Discussion of the treatment strategies should be interdisciplinary and include chemoradiation therapy and radical surgery. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - February 14, 2020 Category: General Medicine Source Type: research

Atrial myxoma with cerebellar signs: a case report
AbstractBackgroundAtrial myxoma remains a rare clinical entity with an incidence of surgically resected cases of 0.5 –0.7 per million population and prevalence of
Source: Journal of Medical Case Reports - February 13, 2020 Category: General Medicine Source Type: research

Isolated agenesis of the corpus callosum and normal general intelligence development during postnatal life: a case report and review of the literature
ConclusionsIsolated agenesis of the corpus callosum is not innocuous, and patients with this defect require a strict neurocognitive follow-up. We provide an informative reference tool useful for the postnatal neuropsychological screening of patients with isolated agenesis of the corpus callosum. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - February 12, 2020 Category: General Medicine Source Type: research

Proximal femoral focal deficiency – a rare congenital entity: two case reports and a review of the literature
ConclusionsThe discovery of two cases of proximal femoral focal deficiency, a rare entity, from referrals for conventional radiography in our Radiology Department encourages literature documentation. Such recognition will facilitate early institution of management, thus ensuring meaningful childhood growth. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - February 5, 2020 Category: General Medicine Source Type: research

Thrombotic microangiopathy and liver toxicity due to a combination therapy of leflunomide and methotrexate: a case report
ConclusionsUnder a combination of leflunomide and methotrexate, liver toxicity and, for the first time, thrombotic microangiopathy occurred as side effects. Non-alcoholic fatty liver disease may have predisposed for the drug-induced liver toxicity. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - February 5, 2020 Category: General Medicine Source Type: research

Robotic voluminous paraesophageal hernia repair: a case report and review of the literature
ConclusionsVarious reports published in the literature suggested that the robot-assisted approach was effective and was associated with very low postoperative morbidity and was accompanied by satisfactory symptomatic and anatomical radiological outcomes during a follow-up period.The robotic approach to paraesophageal repair is safe and effective with low complication rates. With increased experience, the operative time, length of stay, and complications decrease without compromising surgical principles. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - February 4, 2020 Category: General Medicine Source Type: research

Bradycardia and syncope as sole manifestations of a  cranial lesion: a case report
ConclusionTo the best of our knowledge this is the first case report demonstrating central nervous system-related bradycardia and syncope without other neurological symptoms. This case will serve as a useful reminder to general practitioners, accident and emergency doctors, and cardiologists. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 31, 2020 Category: General Medicine Source Type: research

Acute kidney injury and hepatitis associated with energy drink consumption: a case report
ConclusionMultiple cases of energy drink-induced acute kidney injury or acute hepatitis are reported in the literature but this case is the first to report them simultaneously. Ingredients and presumed doses to cause these events are outlined in this case report. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 29, 2020 Category: General Medicine Source Type: research

Coupled blue and red light-emitting diodes therapy efficacy in patients with rosacea: two case reports
ConclusionsThis kind of treatment could represent an effective, safer, and well-tolerated approach for the treatment of such conditions. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 28, 2020 Category: General Medicine Source Type: research

A patient with left-sided inferior vena cava who received oblique lumbar interbody fusion surgery: a case report
ConclusionsTo date, this is the first reported case where a patient underwent oblique lateral interbody fusion surgery in a left lateral decubitus position due to a left-sided inferior vena cava. This case demonstrates that carefully reading radiological results is important for operation planning and avoiding anatomical complications. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 27, 2020 Category: General Medicine Source Type: research

A 14-year-old female with fever, rash, lymphadenopathy, and pancytopenia: a case report
ConclusionsChlorpheniramine as a simple treatment was provided for this syndrome. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 26, 2020 Category: General Medicine Source Type: research

Valproate-induced hyperammonemic encephalopathy: a case report
ConclusionFortunately, rapid identification of this rare condition led to a favorable outcome in our patient. This case report illustrates the course of treatment in a patient who experienced this reaction and reviews current knowledge as well as areas of needed research in regard to valproate-induced hyperammonemic encephalopathy. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 25, 2020 Category: General Medicine Source Type: research

Scurvy may occur even in children with no underlying risk factors: a case report
ConclusionsScurvy is caused by vitamin C deficiency. Cutaneous bleeding, mucosal bleeding, and anemia represent typical manifestations of the disease. These symptoms are directly connected to ascorbic acid involvement in collagen biosynthesis. Some radiographic findings can be useful for the diagnosis. Treatment aims to normalize serum levels of vitamin C in order to counteract the deprivation symptoms. The present case report demonstrates that scurvy may sporadically occur in pediatric patients, even in individuals with no predisposing medical conditions and/or potential risk factors. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 24, 2020 Category: General Medicine Source Type: research

Spontaneous inflammation and necrosis of the falciform and round ligaments: a  case report and review of the literature
ConclusionsIsolated falciform and round-ligament inflammation and necrosis is a rare condition that is difficult to diagnose because it can present mimicking a wide variety of intra-abdominal pathologies, particularly gallbladder pathologies. It is often best treated by laparoscopic resection. Unlike prior reports, our review of the literature, which is the largest that we know of to date, shows that males and females are equally affected. Greater awareness of this entity will aid in future diagnosis. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 23, 2020 Category: General Medicine Source Type: research

Iatrogenic bile duct injury during cholecystectomy presenting after 11 years as a  biliary stricture: a case report
ConclusionBenign biliary stricture can present even decades after cholecystectomy. Roux-en-Y hepaticojejunostomy is the treatment of choice, and a long-term favorable outcome can be expected. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 22, 2020 Category: General Medicine Source Type: research

Multiple electrolyte imbalances and mixed acid-base disorder posing a diagnostic dilemma: a case report
ConclusionBoth patient history and laboratory analysis have a role in identifying and confirming a diagnosis. In cases in which laboratory tests are incongruous with reported history, making a unifying diagnosis can be challenging or delayed. The importance of taking a comprehensive history cannot be overemphasized, but history provided by patients may be prone to intentional or unintentional distortion, whereas laboratory findings are more objective. The case presented underscores why the lab findings should be given credence in cases in which there is discordance between lab results and the provided patient history. (Sou...
Source: Journal of Medical Case Reports - January 20, 2020 Category: General Medicine Source Type: research

3-D printing model used to streamline surgical procedures for an intricate condition of airway compression caused by devastating mediastinal chondrosarcoma: a  case report
ConclusionsAn advanced 3-D printing model provides affirmative information related to treatment strategy and is also a prospective tool for better doctor –patient communication regarding the disease. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 19, 2020 Category: General Medicine Source Type: research

Symptomatic congenital Morgagni hernia presenting as a chest pain: a case report
ConclusionMorgagni hernia is a rare form of congenital diaphragmatic hernia. It is commonly found either in the first few hours of life or in the antenatal period. It is less common in adults and is usually diagnosed accidentally in asymptomatic patients. Symptomatic adult cases are extremely rare. Respiratory symptoms are the most common presenting symptoms. The primary management for both symptomatic and incidentally discovered asymptomatic cases of Morgagni hernia is surgical correction. Various thoracic and abdominal surgical approaches have been described without a clear consensus on preference for operative repair te...
Source: Journal of Medical Case Reports - January 18, 2020 Category: General Medicine Source Type: research

Composite Epstein-Barr virus-positive mucosa-associated lymphoid tissue lymphoma and Epstein-Barr virus-negative diffuse large B-cell lymphoma in the parotid salivary gland of a patient with Sj ögren’s syndrome and rheumatoid arthritis: a case report
ConclusionsOur patient ’s case highlights the importance of assessing the clonal relationships of the lymphoid components of a composite lymphoma and Epstein-Barr virus screening in mucosa-associated lymphoid tissue lymphoma in patients with autoimmune disease. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 17, 2020 Category: General Medicine Source Type: research

Calcification and abscess formation around the catheter tip of a central venous access port: a case report
ConclusionsCatheter-related complications of central venous catheter placement include vascular occlusion, extravasation of the infusion, and infection. However, abnormal calcification in the blood vessels is extremely rare, and there has been only one case report of a neonate with central venous catheter-related vascular calcification in Japan. The etiology of intravascular calcification is considered to be related to the infusion content and the infusion rate of high caloric infusions and blood products. The incidence of complications associated with long-term central venous catheter placement is expected to increase wit...
Source: Journal of Medical Case Reports - January 16, 2020 Category: General Medicine Source Type: research

A rare association between true thymic hyperplasia and thyroid follicular tumor: a case report
ConclusionsWe present a case of a combination of true thymic hyperplasia and thyroidal follicular tumors that, to our knowledge, has not been reported previously. High serum thyroglobulin levels might play a role in hyperplasia of the thymus. Although true thymic hyperplasia is a rare disorder, it should be included in the differential diagnosis of a mediastinal mass in patients with thyroid disease. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 15, 2020 Category: General Medicine Source Type: research

Hemiarthroplasty in a patient with femoral neck fracture and pyoderma gangrenosum: a  case report and review of the literature
ConclusionsIn our patient, the preoperative steroid treatment, perioperative antibiotics, and soft tissue protective surgical technique led to successful management of this rare coincidence. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 14, 2020 Category: General Medicine Source Type: research

Atypical hemolytic uremic syndrome: a case report
ConclusionThe atypical hemolytic uremic syndrome is a rare disease entity requiring a high index of suspicion to diagnose. It is a diagnosis of exclusion. Early diagnosis with prompt treatment will render a better outcome. The atypical hemolytic uremic syndrome needs to be considered in all patients with thrombotic microangiopathy. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 13, 2020 Category: General Medicine Source Type: research

Occurrence of abscesses during treatment with pazopanib in metastatic renal cancer: a case report
ConclusionsWe conclude that abscesses of metastases could be a rare side effect occurring during treatment with pazopanib in patients with renal cancer. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 11, 2020 Category: General Medicine Source Type: research

Hydatid cyst of the foot: a case report
ConclusionsThe rare location and uncommon incidence made the initial diagnosis of hydatid cyst of the foot difficult. Detection of the typical germinal membrane can guide the diagnosis of hydatid cyst in rare locations that are found incidentally. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 10, 2020 Category: General Medicine Source Type: research

The Landscape Montage Technique for diagnosing frontotemporal dementia starting as primary progressive aphasia: a case report
ConclusionsThe present study showed that the Landscape Montage Technique can be useful for diagnosing behavioral variant frontotemporal dementia that starts as logopenic variant primary progressive aphasia at earlier stages. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 9, 2020 Category: General Medicine Source Type: research

Clear cell renal carcinoma synchronous with dedifferentiated liposarcoma: a case report and review of the literature
ConclusionsWe present the first reported case of clear cell renal carcinoma synchronous with dedifferentiated liposarcoma of a limb. The association between renal cell carcinoma and dedifferentiated liposarcoma is unusual, and there are few reports of this presentation in the literature. More research about these tumors along with genetic tests needs to be performed to seek a better understanding of the fundamental basis of this rare association. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 8, 2020 Category: General Medicine Source Type: research

Iatrogenic endometriosis following apical pelvic organ prolapse surgery: a case report
ConclusionAlthough the rate of iatrogenic endometriosis is low after laparoscopic supracervical hysterectomy and sacrocervicopexy, the possibility of the occurrence of iatrogenic endometriosis should be discussed with patients who are diagnosed with apical prolapse to determine the type of surgical intervention. Iatrogenic endometriosis should be kept in mind for differential diagnosis in case of pain after laparoscopic supracervical hysterectomy and sacrocervicopexy. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 5, 2020 Category: General Medicine Source Type: research

Laryngeal polyp associated with reflux disease: a  case report
ConclusionThis report focuses on the pathological findings associated with a laryngeal polyp in a young patient diagnosed with severe reflux disease. Acknowledging such characteristic changes in a laryngeal polyp could aid in the diagnosis of gastroesophageal reflux disease. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 4, 2020 Category: General Medicine Source Type: research

Malfunctioning sufentanil intrathecal pain pump: a case report
ConclusionsBecause of the absence of a clinically significant withdrawal in this case report, clinicians must be aware of relevant pharmacokinetic properties and unusual intrathecal drug delivery system technologies that influence a patient ’s response when device malfunction occurs. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 3, 2020 Category: General Medicine Source Type: research

Infective myositis, an uncommon presentation of melioidosis: a case report and review of the literature
ConclusionMelioidosis is commonly an undiagnosed disease that has a wide variety of clinical presentations. Myositis in melioidosis is uncommon, and careful evaluation is mandatory to avoid misdiagnosis of this treatable but fatal disease. The clinician should have a high index of clinical suspicion, and further clinical and epidemiological studies are needed to determine the true burden of the disease. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - December 31, 2019 Category: General Medicine Source Type: research

Pseudo-Wellens syndrome, acute pancreatitis, and an anomalous coronary artery: a case report
ConclusionsClinicians may consider deferring immediate cardiac catheterization and attribute electrocardiogram changes to acute pancreatitis in patients presenting with angina pectoris and acute pancreatitis if confirmed by normal cardiac enzymes and elevated levels of lipase and amylase. However, when clinical signs and electrocardiogram findings are highly suggestive of myocardial ischemia/injury, immediate noninvasive coronary computed tomography angiography may be the best approach to make an early diagnosis. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - December 30, 2019 Category: General Medicine Source Type: research

One-month-old girl presenting with pseudohypoaldosteronism leading to the diagnosis of CDK13 -related disorder: a  case report and review of the literature
ConclusionsProbably pseudohypoaldosteronism was a coincidental finding in this girl with aCDK13 mutation, but because only limited information is known aboutCDK13-related disorders, further investigation could be more informative to clarify this presentation. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - December 29, 2019 Category: General Medicine Source Type: research

Activating BRAF mutation in sclerosing mucoepidermoid carcinoma with eosinophilia of the thyroid gland: two  case reports and review of the literature
ConclusionsOur findings suggest, for the first time, to our knowledge, involvement of the RAS-RAF-MEK-ERK signaling pathway in the pathogenesis of sclerosing mucoepidermoid carcinoma with eosinophilia. Thus, BRAF inhibitors may prove to be a useful targeted medical therapy in the treatment of a subset of patients with aggressive sclerosing mucoepidermoid carcinoma with eosinophilia tumors who exhibitBRAF activating mutation. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - December 28, 2019 Category: General Medicine Source Type: research

Polyneuropathy, organomegaly, endocrinopathy, monoclonal band, and skin (POEMS) changes syndrome presenting with a pseudosensory level: a case report
ConclusionsPolyneuropathy in polyneuropathy, organomegaly, endocrinopathy, monoclonal band, and skin changes syndrome can present as a pseudosensory level. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - December 27, 2019 Category: General Medicine Source Type: research