Interdisciplinary orthodontic ‐periodontal treatment of unerupted permanent maxillary incisors following traumatic injury to deciduous teeth. Case report with long‐term follow‐up (11 years)
Orthodontic and periodontal treatment of the permanent maxillary teeth, which were retained due to trauma on the deciduous dentition, showed a perfect alignment of the teeth associated with healthy and stable periodontal tissues during an 11 ‐year follow‐up. AbstractOrthodontic and periodontal treatment of the permanent maxillary teeth, which were retained due to trauma on the deciduous dentition, showed a perfect alignment of the teeth associated with healthy and stable periodontal tissues during an 11 ‐year follow‐up. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 8, 2021 Category: General Medicine Authors: Aldo Crescini, Giovan Paolo Pini Prato, Debora Franceschi Tags: CASE REPORT Source Type: research

Lorlatinib ‐induced visual and auditory hallucinations: A case report
Lorlatinib can cause visual and auditory hallucinations. And, it is necessary to keep in mind that hallucinations can persist even after discontinuation in patients who develop hallucinations while receiving lorlatinib. AbstractLorlatinib can cause visual and auditory hallucinations. And, it is necessary to keep in mind that hallucinations can persist even after discontinuation in patients who develop hallucinations while receiving lorlatinib. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 8, 2021 Category: General Medicine Authors: Jun Hakamata, Hideo Nakada, Hiroshi Muramatsu, Keita Masuzawa, Hideki Terai, Shinnosuke Ikemura, Koichi Fukunaga, Tohru Aomori Tags: CASE REPORT Source Type: research

A longitudinal case series of IM ketamine for patients with severe and enduring eating disorders and comorbid treatment ‐resistant depression
We report on four patients with enduring EDs and TRD treated with repeat ketamine over 12 + months, showing improvement in depression with only modest changes in ED symptoms. AbstractSevere and enduring eating disorders (EDs) have the highest mortality rate of all psychiatric illnesses (Arch Gen Psychiatry, 2011,68, 724), especially when comorbid with treatment ‐resistant depression (TRD) (Psychiatr Res, 2016,244, 45). We report on four patients with enduring EDs and TRD treated with repeat ketamine over 12  + months, showing improvement in depression with only modest changes in ED symptoms. (Source: ...
Source: Clinical Case Reports - April 6, 2021 Category: General Medicine Authors: Terry Schwartz, Mary Ellen Trunko, David Feifel, Emily Lopez, Danika Peterson, Guido K. W. Frank, Walter Kaye Tags: CASE REPORT Source Type: research

An anomalous story of a rare percutaneous intervention to left anterior descending/right coronary artery bifurcation
Bifurcation lesions in anomalous coronary arteries are rare. Percutaneous intervention in such lesions is challenging and necessitates use of nonstandard hardware like GuideLiner catheter (Vascular Solutions) for adequate access and support. AbstractBifurcation lesions in anomalous coronary arteries are rare. Percutaneous intervention in such lesions is challenging and necessitates use of nonstandard hardware like GuideLiner catheter (Vascular Solutions) for adequate access and support. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 5, 2021 Category: General Medicine Authors: Harinder Kumar Bali, Amreen Dhindsa, Sankalp Bharti Tags: CASE REPORT Source Type: research

“Inside‐Out” Central Venous Access approach with infraclavicular exit for right‐sided CRT‐D Implantation in bilateral brachiocephalic and superior vena cava occlusion
The use of the “inside‐out” approach with an infraclavicular exit site with a dedicated system in the presence of complex central venous occlusion is feasible and safe for the implantation of complex cardiac devices. AbstractThe use of the “inside‐out” approach with an infraclavicular exit site with a dedicated system in the presence of complex central venous occlusion is feasible and safe for the implantation of complex cardiac devices. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 5, 2021 Category: General Medicine Authors: Johanna B. Tonko, Stephen A. Black, Christopher A. Rinaldi Tags: CASE REPORT Source Type: research

Primary age ‐related EBV‐associated effusion‐based lymphoma successfully treated with rituximab and thoracentesis
EBV ‐positive HHV8‐negative EBL is part of the spectrum of EBV‐positive diffuse large B‐cell lymphoma NOS. This entity can be labeled as primary age‐related EBV‐associated EBL and appears to respond well to rituximab and thoracentesis. AbstractEBV ‐positive HHV8‐negative EBL is part of the spectrum of EBV‐positive diffuse large B‐cell lymphoma NOS. This entity can be labeled as primary age‐related EBV‐associated EBL and appears to respond well to rituximab and thoracentesis. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 5, 2021 Category: General Medicine Authors: Justin J. Kuhlman, Muhamad Alhaj Moustafa, Alexander J. Tun, David M. Menke, Han W. Tun, Liuyan Jiang Tags: CASE REPORT Source Type: research

Dermatofibrosarcoma protuberans in a child, that ’s why soft tissue lesions are not always innocent in children
Pediatric soft tissue tumors should be always operated and sent for a biopsy. AbstractPediatric soft tissue tumors should be always operated and sent for a biopsy. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 4, 2021 Category: General Medicine Authors: Katerina Kambouri, Paschalis Chatzipantelis, Soultana Foutzitzi, Chrysavgi Dimitriadou, Maria Aggelidou, Alexandra Giatromanolaki, Savas Deftereos Tags: CASE REPORT Source Type: research

Carotid artery ligation via sternotomy as a palliative surgery: Case report of advanced intramediastinal malignant soft tissue tumor
Under extreme conditions and in palliative settings, shared decision making with the patient is vital; narrative decisions beyond evidence could be considered. If there is a chance of symptom palliation, extended surgery should not be avoided merely because of the limited life expectancy. AbstractUnder extreme conditions and in palliative settings, shared decision making with the patient is vital; narrative decisions beyond evidence could be considered. If there is a chance of symptom palliation, extended surgery should not be avoided merely because of the limited life expectancy. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 2, 2021 Category: General Medicine Authors: Kohtaro Eguchi, Kenya Kobayashi, Tomonari Takano, Akiko Ito, Azusa Sakai, Atsuo Ikeda, Yoshifumi Matsumoto, Go Omura, Fumihiko Matsumoto, Seiichi Yoshimoto Tags: CASE REPORT Source Type: research

Multiple nodular opacities only involving the right middle pulmonary lobe: Unusual manifestation of tuberculosis
Bronchoscopy should be actively performed to differentiate pulmonary tuberculosis in patients with lesions in the middle lobe, which are unaccompanied by bronchiectasis or present without obvious lesions in other lobes. AbstractBronchoscopy should be actively performed to differentiate pulmonary tuberculosis in patients with lesions in the middle lobe, which are unaccompanied by bronchiectasis or present without obvious lesions in other lobes. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 1, 2021 Category: General Medicine Authors: Akihito Okazaki, Yoshihiro Takeda, Yasuhiko Matsuda, Kentaro Fujita, Kazuhiko Shibata Tags: CLINICAL IMAGE Source Type: research

Mantle cell lymphoma involving the thyroid gland
Mantle cell lymphoma (MCL) rarely involves thyroid gland. Positron emission tomography –computed tomography (PET‐CT) may be critical in identifying thyroid involvement by MCL and pursuing further work up of the suspicious thyroid lesions, irrespective of the thyroid function tests. AbstractMantle cell lymphoma (MCL) rarely involves thyroid gland. Positron emission tomography –computed tomography (PET‐CT) may be critical in identifying thyroid involvement by MCL and pursuing further work up of the suspicious thyroid lesions, irrespective of the thyroid function tests. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 1, 2021 Category: General Medicine Authors: Georgios N Pongas, Juan Pablo Alderuccio, Jennifer R. Chapman, Izidore S Lossos Tags: CASE REPORT Source Type: research

Erector spinae plane block in laparoscopic nephrectomy as a cause of involuntary hemodynamic instability: A case report
The Ultrasound ‐guided erector spinae plane block (US‐ESPB), used as an anesthesiological block for opioid‐sparing approach and for postoperative analgesia, could represent an involuntary cause of hemodynamic instability. This hemodynamic instability is accentuated by a greater diffusion of local anesthetic in the epidural space. AbstractThe Ultrasound ‐guided erector spinae plane block (US‐ESPB), used as an anesthesiological block for opioid‐sparing approach and for postoperative analgesia, could represent an involuntary cause of hemodynamic instability. This hemodynamic instability is accentuated by a greater...
Source: Clinical Case Reports - March 31, 2021 Category: General Medicine Authors: Antonio Coviello, Ludovica Golino, Alfredo Maresca, Maria Vargas, Giuseppe Servillo Tags: CASE REPORT Source Type: research

Raoultella terrigena: Current state of knowledge, after two recently identified clinical cases in Eastern Europe
Raoultella terrigena is a rarely found opportunistic pathogen that can cause healthcare ‐associated infections with high mortality. It is important to differentiate it from Klebsiella species. AbstractRaoultella terrigena is a rarely found opportunistic pathogen that can cause healthcare ‐associated infections with high mortality. It is important to differentiate it from Klebsiella species. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 31, 2021 Category: General Medicine Authors: Nadiia Lekhniuk, Ulbolgan Fesenko, Yaroslav Pidhirnyi, Alicja S ękowska, Olena Korniychuk, Yulian Konechnyi Tags: CASE REPORT Source Type: research

Extraosseous osteoblastoma: A rare cause of breast mass in a prepubertal girl
Extraosseous osteoblastoma of the breast, a rare disease, was diagnosed in a prepubertal girl. After tumor excision, the patient recovered well and an optimal cosmetic result was achieved. Interdisciplinary discussions about the case are essential. AbstractExtraosseous osteoblastoma of the breast, a rare disease, was diagnosed in a prepubertal girl. After tumor excision, the patient recovered well and an optimal cosmetic result was achieved. Interdisciplinary discussions about the case are essential. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 31, 2021 Category: General Medicine Authors: Sabine Danzinger, Leo Kager, Maria Bernathova, Susanna Lang, Werner Haslik, Christian F. Singer Tags: CASE REPORT Source Type: research

Dual aortic aneurysms with coronary artery and multiple cerebrovascular stenoses
Total debranching thoracic endovascular aortic repair is useful for avoiding neurological complications in cases where cardiopulmonary bypass is difficult and for devising an intraoperative cervical branch reconstruction method. AbstractTotal debranching thoracic endovascular aortic repair is useful for avoiding neurological complications in cases where cardiopulmonary bypass is difficult and for devising an intraoperative cervical branch reconstruction method. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 30, 2021 Category: General Medicine Authors: Masafumi Hashimoto, Kenji Mogi, Manabu Sakurai, Kengo Tani, Shuntaro Ito, Yoshiharu Takahara Tags: CASE REPORT Source Type: research

Aortic valve replacement in a patient with sickle cell disease —Are we justified to perform surgery in the TAVI era?
Not all variants of SCD need the same management and this should be decided on a case ‐by‐case basis. Heterozygous SCD patients can undergo cardiac surgery without the need for intraoperative exchange transfusions with good clinical outcomes. AbstractNot all variants of SCD need the same management and this should be decided on a case ‐by‐case basis. Heterozygous SCD patients can undergo cardiac surgery without the need for intraoperative exchange transfusions with good clinical outcomes. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 30, 2021 Category: General Medicine Authors: Ramanish Ravishankar, Leenah Turkistani, Yasser Elghoneimy, Imthiaz Manoly Tags: CASE REPORT Source Type: research

Ileocecal and hepatic tuberculosis mimicking a metastatic cecal malignancy: Case report
We wish to highlight that on encountering a suspicious hepatic and a colonic lesion, the possibility of TB should also be kept in mind apart from the obvious possibility of metastasis of a colonic cancer especially in an endemic country like Tunisia. AbstractWe wish to highlight that on encountering a suspicious hepatic and a colonic lesion, the possibility of TB should also be kept in mind apart from the obvious possibility of metastasis of a colonic cancer especially in an endemic country like Tunisia. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 29, 2021 Category: General Medicine Authors: Imen Ben Ismail, Saber Rebii, Hamadi Ben Chaabane, Zenaidi Hakim, Ayoub Zoghlami Tags: CASE REPORT Source Type: research

Management of perioperative acute massive pulmonary embolism: A case series
The management of acute massive pulmonary embolism during the perioperative period is challenging. Accurate diagnosis using echocardiography and application of rapid extracorporeal membrane oxygenation can improve patients' outcomes. AbstractThe management of acute massive pulmonary embolism during the perioperative period is challenging. Accurate diagnosis using echocardiography and application of rapid extracorporeal membrane oxygenation can improve patients' outcomes. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 29, 2021 Category: General Medicine Authors: Ji ‐Yoon Kim, Young‐Seok Lee, Hyun Oh Park, Il Woo Shin Tags: CASE REPORT Source Type: research

Modified BLUE protocol ultrasonography can diagnose thrombotic complications of COVID ‐19 with normal lung ultrasound
The BLUE protocol provides an excellent step ‐by‐step approach for diagnosis of acute dyspnea. Adding FECHO (Focused Echocardiography) to the BLUE protocol completes the picture and helps make solid diagnoses, especially in submassive and massive PE (Pulmonary embolism). COVID‐19 infection can present with thrombotic manifestations like DVT (Deep vein thrombosis) and PE with no ultrasonographic evidence of lung parenchymal affection. AbstractThe BLUE protocol provides an excellent step ‐by‐step approach for diagnosis of acute dyspnea. Adding FECHO (Focused Echocardiography) to the BLUE protocol completes the pict...
Source: Clinical Case Reports - March 29, 2021 Category: General Medicine Authors: Tamer Mohamed Zaalouk, Zouheir Ibrahim Bitar, Ossama Sajeh Maadarani, Ragab Desouky Ragab Elshabasy Tags: CASE REPORT Source Type: research

A case report of idiopathic Hemophagocytic lymphohistiocytosis in an immunocompetent adult
Hemophagocytic lymphohistiocytosis poses a diagnostic dilemma due to the absence of specific clinical and laboratory findings, especially in adults. Despite greater recognition of the disease, secondary idiopathic forms are still reported. AbstractHemophagocytic lymphohistiocytosis poses a diagnostic dilemma due to the absence of specific clinical and laboratory findings, especially in adults. Despite greater recognition of the disease, secondary idiopathic forms are still reported. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 29, 2021 Category: General Medicine Authors: Tiago Rabad ão, Leonor Naia, Filipa Ferreira, Mariana Teixeira, Marcelo Aveiro, Margarida Eulálio, Fernando Silva Tags: CASE REPORT Source Type: research

Statin ‐associated necrotizing autoimmune myopathy with concurrent myasthenia gravis
We present an unprecedented clinical challenge with both disorders occurring in a patient treated with statins few months earlier. AbstractStatin treatment has been associated with necrotizing autoimmune myopathy and has been linked to myasthenia gravis. We present an unprecedented clinical challenge with both disorders occurring in a patient treated with statins few months earlier. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 29, 2021 Category: General Medicine Authors: Emma Frasson, Marco Simonetto, Laura Bertolasi, Giorgio Caneve, Cristina Vilotti, Giampietro Ruzza, Anna Perelli, Maria Grazia Piccinno, Salvatore Monaco Tags: CASE REPORT Source Type: research

Chromosome 22q11.21 and 11p15.4 microdeletions confirmed by high ‐throughput sequencing analysis in one patient with asymmetric cry syndrome: Case report and review of the literature
Healthcare providers treating newborns with asymmetric cry syndrome should consider 22q11.2 microdeletion within the differential diagnosis list and order appropriate genetic testing. AbstractHealthcare providers treating newborns with asymmetric cry syndrome should consider 22q11.2 microdeletion within the differential diagnosis list and order appropriate genetic testing. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 28, 2021 Category: General Medicine Authors: Yonghong Pang, Yang Yu, Xiaoyi Deng, Qian Liu, Junmei Yan, Xiangyu Gao Tags: CASE REPORT Source Type: research

Transition of maternal serum concentration of digoxin and flecainide in the third trimester —A case report of fetal supraventricular tachycardia with hydrops
When transplacental therapy is conducted, the maternal serum concentrations of digoxin and flecainide may fluctuate throughout third trimester. Therefore, TDM may be effective in improving the efficacy and safety of treatment. AbstractWhen transplacental therapy is conducted, the maternal serum concentrations of digoxin and flecainide may fluctuate throughout third trimester. Therefore, TDM may be effective in improving the efficacy and safety of treatment. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 27, 2021 Category: General Medicine Authors: Hirokazu Takatsuka, Kayo Wakabayashi, Shingo Yamazaki, Hirokazu Tanaka, Akiko Omoto, Takaaki Suzuki, Makio Shozu, Itsuko Ishii Tags: CASE REPORT Source Type: research

Hyperandrogenism, oligomenorrhea, and erythrocytosis caused by an ovarian Leydig cell tumor: A case report
Leydig cell tumors are rare ovarian neoplasms. Affected individuals typically present with amenorrhea/oligomenorrhea and rapidly progressive features of virilization. Erythrocytosis can also occur as a result of high testosterone levels. AbstractLeydig cell tumors are rare ovarian neoplasms. Affected individuals typically present with amenorrhea/oligomenorrhea and rapidly progressive features of virilization. Erythrocytosis can also occur as a result of high testosterone levels. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 26, 2021 Category: General Medicine Authors: Fernando Mendon ça, Selma Souto, Daniela Magalhães, Raquel Portugal, Ana Rita Coelho, Ana Sofia Fernandes, Vera Falcão, Sara Tavares, Inês Portugal, Jorge Beires, Davide Carvalho Tags: CASE REPORT Source Type: research

Corticosteroid therapy for 2019 ‐nCoV‐infected patients: A case series of eight mechanically ventilated patients
High ‐dose short‐term corticosteroid therapy is effective and produces favorable clinical outcome in patients with severe 2019‐nCoV infection who are candidates for mechanical ventilation with close monitoring for the adverse effect of corticosteroids. AbstractHigh ‐dose short‐term corticosteroid therapy is effective and produces favorable clinical outcome in patients with severe 2019‐nCoV infection who are candidates for mechanical ventilation with close monitor/ing for the adverse effect of corticosteroids. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 26, 2021 Category: General Medicine Authors: Mabrouk AL ‐Rasheedi, Yasir Alhazmi, Nouf Almaqwashi, Alreshidi Mateq Ali, Abdulaziz Kardam, Mohammod Sharaf, Khawaja Husnain Haider Tags: CASE REPORT Source Type: research

Neurosarcoidosis with hydrocephalus as a first presenting sign: a unique case report
There is a possible relationship with cerebral ischemic events and neurosarcoidosis. It should be considered in the differential diagnosis in a case of unexplained hydrocephalus, vascular white matter lesions and vasculitis related findings. AbstractThere is a possible relationship with cerebral ischemic events and neurosarcoidosis. It should be considered in the differential diagnosis in a case of unexplained hydrocephalus, vascular white matter lesions and vasculitis related findings. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 25, 2021 Category: General Medicine Authors: Val érie N. E. Schuermans, Esther Yeung, Wouter J. P. Henneman, Linda Ackermans, Roel Heijboer, Rémy L. M. Mostard, Winand Vos, Raphaël Pasmans, Olaf E. M. G. Schijns Tags: CASE REPORT Source Type: research

Treatment of toxoplasmic encephalitis with the combination of clindamycin plus azithromycin in an HIV ‐infected patient: A case report
The existence of alternative oral therapies could help clinicians to treat toxoplasmic encephalitis (TE) in the HIV patients. The combination of azithromycin and clindamycin may serve as an effective treatment for TE in HIV ‐infected patients. AbstractThe existence of alternative oral therapies could help clinicians to treat toxoplasmic encephalitis (TE) in the HIV patients. The combination of azithromycin and clindamycin may serve as an effective treatment for TE in HIV ‐infected patients. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 24, 2021 Category: General Medicine Authors: Keyhan Mohammadi, Hossein Khalili, Sirous Jafari, Shakila Yaribash Tags: CASE REPORT Source Type: research

Fulminant hepatorenal syndrome due to Acetaminophen toxicity: A case report
HRS is a rare and poor prognosis complication of chronic acetaminophen toxicity, which presents by progressive decline in renal function secondary to liver failure. AbstractHRS is a rare and poor prognosis complication of chronic acetaminophen toxicity, which presents by progressive decline in renal function secondary to liver failure. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 24, 2021 Category: General Medicine Authors: Zahra Nekoukar, Minoo Moghimi, Zakaria Zakariaei, Mahdi Fakhar, Rabeeh Tabaripour Tags: CASE REPORT Source Type: research

Epidermal growth factor receptor inhibitor in advanced basal cell carcinoma
Cetuximab can be used for the treatment of advanced basal cell carcinoma, especially when the patient cannot tolerate routine chemotherapy. Future studies are needed to confirm it. AbstractCetuximab can be used for the treatment of advanced basal cell carcinoma, especially when the patient cannot tolerate routine chemotherapy. Future studies are needed to confirm it. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 24, 2021 Category: General Medicine Authors: Amir Amirabadi, Amirhosein Alami, Hamid Ahanchian, Nazila Ariaee, Nasrin Moazzen Tags: CASE REPORT Source Type: research

Ocular heterotopic bone formation in a guinea pig: A case report with 7 ‐month follow‐up using advanced ophthalmic imaging technology
Advanced ophthalmic imaging techniques can provide important clinical insights into the pathophysiological changes in heterotopic bone formation (HBF). This case report revealed progression of ocular HBF in the guinea pig over a period of 7 months. AbstractAdvanced ophthalmic imaging techniques can provide important clinical insights into the pathophysiological changes in heterotopic bone formation (HBF). This case report revealed progression of ocular HBF in the guinea pig over a period of 7 months. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 24, 2021 Category: General Medicine Authors: So Goto, Qiurong Zhu, Kelly Jensen, Josue A. Torres, Christine F. Wildsoet Tags: CASE REPORT Source Type: research

A case of concomitant pulmonary embolism and pulmonary tuberculosis in the era of COVID 19, a matter of cautious approach
TB is known to the world for many years. It is associated with various complications and rarely with pulmonary embolism. However, due to its commonalities of presenting features with COVID 19, it can easily be missed and may be life threatening. AbstractTuberculosis (TB) is known to the world for many years. It is associated with various complications and rarely with pulmonary embolism. However, due to its commonalities of presenting features with COVID 19, it can easily be missed and may be life threatening. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 24, 2021 Category: General Medicine Authors: Sinda Dakhlia, Phool Iqbal, Muhammad Abubakar, Sabeen Zara, Muhammad Murtaza, Adel Al Bozom, Nedia Neffati Tags: CASE REPORT Source Type: research

Friedreich ataxia in a family from Mali, West Africa/Friedreich ataxia in a Malian family
We report the first genetically confirmed case in a West African family. Studying genetic diseases in populations with diverse backgrounds may give new insights into their pathophysiology for future therapeutic targets. AbstractFriedreich ataxia is the most common inherited ataxia in the world, but yet to be reported in black African. We report the first genetically confirmed case in a West African family. Studying genetic diseases in populations with diverse backgrounds may give new insights into their pathophysiology for future therapeutic targets. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 24, 2021 Category: General Medicine Authors: Cheick A. K. Ciss é, Lassana Cissé, Hamidou O. Ba, Oumar Samassékou, Assiatou Simaga, Abdoulaye Taméga, Salimata Diarra, Seybou H. Diallo, Thomas Coulibaly, Salimata Diallo, Abdoulaye Yalcouyé, Alassane B. Maiga, Mohamed Keita, Kenneth H Tags: CASE REPORT Source Type: research

Dissociated response related to corticosteroids in lung cancer treated by immunotherapy: A case report
We report the case of a patient with a complete metastatic adrenal response on Pembrolizumab for metastatic lung cancer. Treatment with a systemic corticosteroid ‐induced a time‐dependent progression at his metastatic site. Surprisingly, after stopping the corticosteroid, we observed a new complete response in long‐term adrenal metastases. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 24, 2021 Category: General Medicine Authors: Quentin Dominique Thomas, L éa Sinoquet, Antonio Maraver, Xavier Quantin Tags: CASE REPORT Source Type: research

Cover Image
The cover image is based on the Case ReportNovel strategy for ostial left anterior descending artery acute myocardial infarction: Combined treatment with directional coronary atherectomy followed by drug ‐coated balloon angioplasty by Hiroyuki Yamamoto et al.,https://doi.org/10.1002/ccr3.3659. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 21, 2021 Category: General Medicine Authors: Hiroyuki Yamamoto, Takahiro Sawada, Tomofumi Takaya, Hiroya Kawai, Yoshinori Yasaka Tags: COVER IMAGE Source Type: research

Issue Information
(Source: Clinical Case Reports)
Source: Clinical Case Reports - March 21, 2021 Category: General Medicine Tags: ISSUE INFORMATION Source Type: research

Reinforced conservative management of post ‐dural puncture headache in a patient with a rare case of tethered cord syndrome using an abdominal binder: A case report
An abdominal binder could be used effectively in a patient showing CSF leakage in the coccygeal area with post ‐dural puncture headache, which is not controlled by conventional compressive dressing. AbstractAn abdominal binder could be used effectively in a patient showing CSF leakage in the coccygeal area with post ‐dural puncture headache, which is not controlled by conventional compressive dressing. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 21, 2021 Category: General Medicine Authors: Miyeong Park, Hokyung Yu, Jiyoung Park, Ju ‐Tae Sohn, Kyeong‐Eon Park, Yeran Hwang, Sunmin Kim, Seong‐Ho Ok Tags: CASE REPORT Source Type: research

Neuroendocrine adenoma of the middle ear —An intriguing entity
Despite its rarity, the neuroendocrine adenoma of the middle ear (NEAME) is a differential diagnosis of the middle ear disease. We suspect that the NEAME is underdiagnosed and more cases can be detected through education and personal experience. Treatment is R0 resection, and long follow ‐up is recommended. AbstractDespite its rarity, the neuroendocrine adenoma of the middle ear (NEAME) is a differential diagnosis of the middle ear disease. We suspect that the NEAME is underdiagnosed and more cases can be detected through education and personal experience. Treatment is R0 resection, and long follow ‐up is recommended. ...
Source: Clinical Case Reports - March 21, 2021 Category: General Medicine Authors: Peter Bou Rahal, Bo W ängberg Tags: CASE REPORT Source Type: research

NTRK2 Fusion driven pediatric glioblastoma: Identification of oncogenic Drivers via integrative Genome and transcriptome profiling
This is the first report of a NACC2 ‐NTRK2 fusion in a histological glioblastoma. Oncogenomic analysis revealed this actionable fusion oncogene in a pediatric cerebellar glioblastoma, which would not have been identified through routine diagnostics, demonstrating the value of clinical genome profiling in cancer care. AbstractThis is the first report of a NACC2 ‐NTRK2 fusion in a histological glioblastoma. Oncogenomic analysis revealed this actionable fusion oncogene in a pediatric cerebellar glioblastoma, which would not have been identified through routine diagnostics, demonstrating the value of clinical genome profil...
Source: Clinical Case Reports - March 21, 2021 Category: General Medicine Authors: Heidi M. Britton, Adrian B. Levine, Yaoqing Shen, Karen Mungall, Jonathan Serrano, Matija Snuderl, Erin Pleasance, Steven J. M. Jones, Janessa Laskin, Marco A. Marra, Shahrad R. Rassekh, Rebecca Deyell, Stephen Yip, Sylvia Cheng, Chris Dunha Tags: CASE REPORT Source Type: research

Prenatal detection of a giant isolated coronary fistula
Prenatal detection of an ICCAF requires an examination of the affected fetal hemodynamic situation by the fistula. Early pediatric cardiological presentation is needed, since prenatal changes may have relevant postpartal consequences. AbstractPrenatal detection of an isolated congenital coronary artery fistula (ICCAF) requires an examination of the affected fetal hemodynamic situation by the fistula. Early pediatric cardiological presentation is needed, since prenatal changes may have relevant postpartal consequences. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 21, 2021 Category: General Medicine Authors: Adeline Walter, Elina Calite, Alexander C. Engels, Ulrike Herberg, Johannes Breuer, Arne Willruth, Christoph Berg, Annegret Geipel, Ulrich Gembruch Tags: CASE REPORT Source Type: research

Platelet function and microvesicle generation in patients with hemophilia A
Our results do not support any effect of FVIII on platelet function in patients with severe HA treated under the regime of prophylaxis. AbstractOur results do not support any effect of FVIII on platelet function in patients with severe HA treated under the regime of prophylaxis. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 21, 2021 Category: General Medicine Authors: Antonia Melero ‐Amor, Paola Romecín, David Iyú, David García‐Bernal, Esther García‐Navaro, José M. Moraleda, Joaquín García‐Estañ, Faustino García‐Candel, Noemí M. Atucha Tags: CASE REPORT Source Type: research

Virtual and real assessment of a wide antral ablated region in atrial fibrillation patients using the hot balloon system
The hot balloon system has become widely used for atrial fibrillation ablation and also has software for preoperative computer simulation. The computer model may be useful for predicting the extent of a wide planar ablation region in the left atrium. AbstractThe hot balloon system has become widely used for atrial fibrillation ablation and also has software for preoperative computer simulation. The computer model may be useful for predicting the extent of a wide planar ablation region in the left atrium. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 21, 2021 Category: General Medicine Authors: Reiko Fukuda, Shiro Nakahara, Hirotsugu Sato, Naoki Nishiyama, Yuichi Hori, Isao Taguchi Tags: CASE REPORT Source Type: research

Renal failure and lung hemorrhage as a presentation of COVID ‐19 infection, a case report
The concurrent involvement of the lung and kidneys happens in COVID ‐19 infection. The patient's respiratory symptoms resolved after hemodialysis. This finding raises the question that if hemodialysis can have a role in the treatment of COVID‐19. AbstractThe concurrent involvement of the lung and kidneys happens in COVID ‐19 infection. The patient's respiratory symptoms resolved after hemodialysis. This finding raises the question that if hemodialysis can have a role in the treatment of COVID‐19. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 21, 2021 Category: General Medicine Authors: Nazanin Zamani, Oldooz Aloosh, Samane Ahsant, Niloofar Khodabandeloo, Tahere Zarook Ahimahalle, Aminreza Abkhoo, Taghi Riahi Tags: CASE REPORT Source Type: research

Lung abscess as a complication of COVID ‐19 infection, a case report
To our knowledge, no previous studies have reported lung abscess as a complication of COVID ‐19 infection. It is essential to follow‐up with the patients after discharge for such complications, especially if they are symptomatic. AbstractTo our knowledge, no previous studies have reported lung abscess as a complication of COVID ‐19 infection. It is essential to follow‐up with the patients after discharge for such complications, especially if they are symptomatic. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 21, 2021 Category: General Medicine Authors: Nazanin Zamani, Oldooz Aloosh, Samane Ahsant, Zeynab Yassin, Aminreza Abkhoo, Taghi Riahi Tags: CASE REPORT Source Type: research

Aggregometry and thromboelastography to identify the timing to trach a COVID ‐19 patient receiving both antiplatelet therapy and enoxaparin
In COVID ‐19 patients receiving enoxaparin and antiplatelets therapy, aggregometry and thromboelastography might be considered an adjunctive tool to identify the time to perform procedures at risk of bleeding, such as tracheostomy. AbstractIn COVID ‐19 patients receiving enoxaparin and antiplatelets therapy, aggregometry and thromboelastography might be considered an adjunctive tool to identify the time to perform procedures at risk of bleeding, such as tracheostomy. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 21, 2021 Category: General Medicine Authors: Marco Tescione, Eugenio Vadal à, Graziella Marano, Andrea Bruni, Eugenio Garofalo, Ovidia Lavalle, Federico Longhini, Enzo Battaglia, Nicola Polimeni, Demetrio Labate, Sarah Caracciolo, Francesco Giordano, Massimo Caracciolo, Sebastiano Mach Tags: CASE REPORT Source Type: research

Massive sacrococcygeal teratoma in a preterm infant
In extreme preterm infants, massive congenital sacrococcygeal teratomas with great hemodynamic commitment may be a situation for limitation of care. AbstractIn extreme preterm infants, massive congenital sacrococcygeal teratomas with great hemodynamic commitment may be a situation for limitation of care. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 21, 2021 Category: General Medicine Authors: Pedro Maneira ‐Sousa, Gustavo Rocha, Paulo Soares, Vanessa Arnet, Susana Guimarães, Ana Catarina Fragoso, Carla Ramalho, Estevão Costa, Hercília Guimarães Tags: CASE REPORT Source Type: research

Use of a novel implantable cardioverter ‐defibrillator multisensor algorithm for heart failure monitoring in a COVID‐19 patient: A case report
We report the case of a patient implanted with an implantable defibrillator endowed with a multisensor algorithm for heart failure monitoring. Automatic measurement of multiple clinical variables allowed to detect impending heart failure decompensation and showed its ability to facilitate differential diagnosis in the context of the current COVID ‐19 pandemic. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 21, 2021 Category: General Medicine Authors: Luca Bontempi, Manuel Cerini, Francesca Salghetti, Davide Fabbricatore, Clara Nozza, Monica Campari, Sergio Valsecchi, Antonio Curnis Tags: CASE REPORT Source Type: research

Significant elevation of free itraconazole concentration at onset of adverse effects: A case report
Free itraconazole and hydroxyitraconazole concentrations were markedly elevated despite almost no changes in total concentrations when itraconazole was discontinued due to adverse effects. Elevated free itraconazole concentration may have a causal relationship with the development of adverse effects. AbstractFree itraconazole and hydroxyitraconazole concentrations were markedly elevated despite almost no changes in total concentrations when itraconazole was discontinued due to adverse effects. Elevated free itraconazole concentration may have a causal relationship with the development of adverse effects. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 21, 2021 Category: General Medicine Authors: Ryota Tanaka, Yosuke Suzuki, Hiroyuki Matsumoto, Mari Yamasue, Kenji Umeki, Kazuhiko Hashinaga, Ryosuke Tatsuta, Kazufumi Hiramatsu, Katsuhiko Kamei, Jun ‐ichi Kadota, Hiroki Itoh Tags: CASE REPORT Source Type: research

Diagnostic features of a non ‐pigmented eccrine poroma with a collarette: Histopathological and dermoscopic correlation
The whitish ‐pink, ovoid nest and translucent‐brown globules with poorly visualized vessels in the collarette are shown (arrows) AbstractThis is a case that emphasized the need for detailed observation of the entire lesion in dermoscopic examination. Novel dermoscopic findings within a collarette. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 21, 2021 Category: General Medicine Authors: Tomoaki Takada Tags: CASE REPORT Source Type: research

Plasma exchange as treatment for acute fatty liver disease of pregnancy
Acute fatty liver disease of pregnancy AFLP is an obstetrical emergency, with severe complications that may include death. Management of AFLP is challenging and include plasma exchange which helps to improve the prognosis for both mother and fetus and delay liver transplantation. AbstractAcute fatty liver disease of pregnancy AFLP is an obstetrical emergency, with severe complications that may include death. Management of AFLP is challenging and include plasma exchange which helps to improve the prognosis for both mother and fetus and delay liver transplantation. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 21, 2021 Category: General Medicine Authors: Mohammed Aabdi, Yassine Mellagui, Jamal Ouachaou, Essad Ounci, Houssam Bkiyar, Brahim Housni Tags: CASE REPORT Source Type: research

A case of cardiopulmonary arrest due to left ventricular free wall rupture successfully treated with sutureless repair supported by venoarterial extracorporeal membrane oxygenation
Extracorporeal membrane oxygenation for cardiopulmonary arrest due to left ventricular free wall rupture is considered effective, because it enables rapid cardiopulmonary support and introduction of targeted temperature management. AbstractExtracorporeal membrane oxygenation for cardiopulmonary arrest due to left ventricular free wall rupture is considered effective, because it enables rapid cardiopulmonary support and introduction of targeted temperature management. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 21, 2021 Category: General Medicine Authors: Ginga Suzuki, Ryo Ichibayashi, Saki Yamamoto, Hibiki Serizawa, Kota Kawada, Toru Kameda, Yoshimi Nakamichi, Masayuki Watanabe, Shinnosuke Okuma, Mitsuru Honda Tags: CASE REPORT Source Type: research

Case of rupture ectopic pregnancy with emergency contraception levonorgestrel 0.075 mg in a lactating woman
Levonorgestrel emergency contraception (LNG ‐EC) tends to make uterus unfavorable for implantation but does not prevent embryo implantation. Emergency contraceptives pills should be used with caution among lactating women who at the same time should be monitored closely for ectopic pregnancy. AbstractLevonorgestrel emergency contraception (LNG ‐EC) tends to make uterus unfavorable for implantation but does not prevent embryo implantation. Emergency contraceptives pills should be used with caution among lactating women who at the same time should be monitored closely for ectopic pregnancy. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 21, 2021 Category: General Medicine Authors: Nazish Masud, Saleh AlShaibi, Tala AlBassri, Saad Khan, Fahad Khan Tags: CASE REPORT Source Type: research