Intra ‐biliary hydatid cyst rupture: A rare case report with superinfection
Abdominal CT (coronal) scan demonstrating elongated left lobe of the liver mimicking a beaver's tail (blue arrow) with the normal right lobe of the liver (red arrow); a beaver tail appearance liver. Key Clinical MessageHydatid cysts, primarily found in the liver (70%), are caused by parasitic infections and can lead to severe complications such as cyst rupture. This case report describes a unique instance of a hydatid liver cyst occupying the right lobe with a communicating part with the biliary tree that ruptured showing a concurrent superinfection.AbstractHydatid cysts are a clinical pathology resulting from parasitic in...
Source: Clinical Case Reports - March 18, 2024 Category: General Medicine Authors: Hanan Al ‐Asbahi, Jaber H. Jaradat, Mohammad Abu‐Jeyyab, Ruba Al‐Dwairi, Bara'a W. Tailakh, Rand A. Almadadha, Ibraheem M. Alkhawaldeh, Abdulqadir J. Nashwan Tags: CASE REPORT Source Type: research

Primary cutaneous plasmacytosis successfully treated with topical corticosteroids and psoralen plus ultraviolet A: A case report
We present a case of primary cutaneous plasmacytosis without systemic involvement. The patient received topical corticosteroids and psoralen plus ultraviolet A therapy, showing significant improvement. Continuous monitoring is underway despite the rarity of systemic manifestations. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 15, 2024 Category: General Medicine Authors: Thanyathorn Nuchanatanon, Settanan Plangsiri, Teerapong Rattananukrom Tags: CASE REPORT Source Type: research

Failure of lipid control by PCSK9 inhibitors in compound heterozygous familial hypercholesterolemia complicated with premature myocardial infarction: A case report
Key Clinical MessageA certain level of low-density lipoprotein receptor activity is crucial for the efficacy of PCSK9i. Therapeutic strategies for familial hypercholesterolemia patients should consider drug efficacy, and genetic testing will be helpful.AbstractFamilial hypercholesterolemia (FH) is a serious autosomal dominant disorder. Managing blood lipids in FH patients poses greater challenges for clinicians. Drug therapy may not always yield satisfactory results, particularly in individuals with low-density lipoprotein receptor (LDLR) negative mutations. Herein, we report a young female harboring an LDLR frameshift mut...
Source: Clinical Case Reports - March 14, 2024 Category: General Medicine Authors: Ziyue Zhang, Rongpei Yang, Jun Zhu, XiaoLi Yang, Hao Luo, Hongyong Wang, Xiaoli Luo Tags: CASE REPORT Source Type: research

Asymptomatic left ventricular pseudoaneurysm
Key Clinical MessageSome cases of left ventricular pseudoaneurysms (LVPAs) are asymptomatic. While cardiac magnetic resonance imaging is important, a chest x-ray can easily be performed and is also crucial for the detection of LVPA during the first outpatient visit. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 14, 2024 Category: General Medicine Authors: Taisuke Hanamura, Daisuke Fukamachi, Masashi Tanaka, Yasuo Okumura Tags: CASE IMAGE Source Type: research

Suspected cutaneous anthrax in a yak herder in a highland community in Bhutan, 2023: A case report
Key clinical messageThis case presents cutaneous anthrax in yak herder from a central highland community in Bhutan. We highlight the clinical presentation, diagnosis and management of the case in a resource-limited setting, and the public health response through the One Health approach. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 14, 2024 Category: General Medicine Authors: Ugyen Chophel, Sangay Dorji, Kuenga Sonam, Thinley Dorji Tags: CASE REPORT Source Type: research

Hybrid approach to management for a patient with culture negative infective endocarditis with profunda femoris mycotic pseudoaneurysm: A case report and review of the literature
We present a case of a patient who underwent mitral valve repair for severe mitral regurgitation secondary to culture negative IE which was complicated by multiple mycotic pseudoaneurysm. The PFA pseudoaneurysm which was affected and was complicated with a large hematoma compressing the femoral nerve. This was managed by a staged hybrid approach. Endovascular stenting was performed first to seal the pseudoaneurysm and facilitate open surgical repair using a reversed interposition saphenous vein graft. To the best of our knowledge, this is the first reported case of a PFA mycotic aneurysm (MA) being managed by a hybrid appr...
Source: Clinical Case Reports - March 14, 2024 Category: General Medicine Authors: Fahad M. Alshair, Abdullah H. Baghaffar, Mazin A. Fatani, Reda A. jamjoom Tags: CASE REPORT Source Type: research

Vaginoscopic resection of hemivagina, in a 20 ‐year‐old virgin female with prior misdiagnosis of OHVIRA syndrome as a bicornuate uterus: A case report
This study presents a 20-year-old virgin female who was diagnosed with OHVIRA syndrome and treated by vaginoscopy using the hymen preservation technique. Also, she was misdiagnosed with non-communicating rudimentary uterine horn 4  years ago. Late or misdiagnosis of OHVIRA syndrome can affect fertility and pregnancy outcomes. Therefore, early diagnosis and management are crucial. OHVIRA syndrome's misdiagnosis is possible with other Mullerian duct anomalies, such as a rudimentary uterine horn. Also, patients with misdiagnos is undergo unnecessary interventions. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 14, 2024 Category: General Medicine Authors: Ameneh Haghgoo, Ali Faegh, Saeed Nasiri, Farnaz Akhbari Tags: CASE REPORT Source Type: research

Retinitis pigmentosa ‐1 due to an RP1 mutation in a consanguineous Iranian family: Report of a novel mutation
Key Clinical MessageThe identification of a novelRP1 gene mutation highlights the importance of precise variant identification for retinitis pigmentosa prognosis and genetic consultations, emphasizing comprehensive genetic analysis for personalized care.AbstractOur study unveils a noteworthy association between retinitis pigmentosa-1 and a newly discovered homozygous mutation (c.5326delC; p.Asp1777Ilefs*32) within theRP1 gene. This highlights the crucial role of accurate variant identification in not only informing prognosis but also improving genetic consultations and influencing future diagnostic approaches for individua...
Source: Clinical Case Reports - March 14, 2024 Category: General Medicine Authors: Mostafa Neissi, Motahareh Sheikh ‐Hosseini, Javad Mohammadi‐Asl Tags: CASE REPORT Source Type: research

Fiberoptic endoscopic assessment of dysphagia in a patient with cutaneous and oropharyngeal blisters
This case study provides fiberoptic endoscopic evidence of pharyngeal dysphagia in a patient with bullous pemphigoid. Key Clinical MessageDysphagia resulting from bulbous pemphigoid is a rare but significant manifestation. A 77-year-old with bullous pemphigoid with no neurological history presented with severe oropharyngeal dysphagia, attributable to underlying blistering and edema, as documented on a fiberoptic endoscopic swallow examination. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 14, 2024 Category: General Medicine Authors: Allison Hughes Bartholow Tags: CASE REPORT Source Type: research

Elderly onset of MELAS carried an M.3243A   > G mutation in a female with deafness and visual deficits: A case report
We report a 52-year-old female with a documented 40-year history of progressive sensorineural hearing loss, developed a visual field deficit and stroke-like events in her middle age who finally diagnosed was MELAS. The patient was started on vitamin E,l-carnitine,l-arginine, and coenzyme Q10 that gradually improved before dismissal from the hospital. This case highlights the importance of considering MELAS as a potential cause of stroke-like events if imaging findings are atypical for cerebral infarction, especially among middle-aged patients without vascular risk factors and an unusual cause of progressive sensorineural h...
Source: Clinical Case Reports - March 14, 2024 Category: General Medicine Authors: Lin Zijun, Yi Xu, Yang Yujia, Xu Zhiqiang Tags: CASE REPORT Source Type: research

Mesenchymal hepatic hamartoma: A rare case of severe respiratory distress in a neonate
Coronal and sagittal computed tomography imaging showing a large cyst lesion of unknown origin, with a smooth outline. Thin septa are seen extending within the lesion. Attenuation values suggest serous fluid, being approximately +20  HU. No signs of hemorrhage or calcification seen. Key Clinical MessageIt is critical to consider intra-abdominal pathology in cases of neonatal respiratory distress. Accurate and prompt diagnosis via computed tomography is lifesaving. We have highlighted the effectiveness of rapid surgical intervention as curative. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 14, 2024 Category: General Medicine Authors: Kareem Omran, Jayasheela Kannan, Nisha Soares, Sameh Ali, Wissam Jamal Al  Tamr Tags: CASE REPORT Source Type: research

Acute myocardial infarction in an untreated patient with acute myeloid leukemia
Key Clinical MessageAcute leukemia, particularly AML, is closely associated with thrombotic events, driven by complex factors like coagulation system changes, endothelial dysfunction, and leukemic cell interactions with the vascular system. Certain chemotherapy drugs can exacerbate the prothrombotic state. Understanding these dynamics is crucial for effective thromboprophylaxis in carefully selected patients with leukemia.AbstractThrombosis is a significant complication of acute leukemia. Thrombotic events mostly occur at diagnosis or during induction therapy. Here we report the occurrence of myocardial infarction (MI) bef...
Source: Clinical Case Reports - March 14, 2024 Category: General Medicine Authors: Doreen Kamoga, Sai Desikan, Raman Desikan, Jackson Musuuza Tags: CASE REPORT Source Type: research

Small bowel obstruction in a 29 ‐year‐old male with congenital peritoneal bands: A rare case report from Syria
We report a case of a 29-year-old male presented with 10  days of severe abdominal pain and vomiting, with no history of abdominal surgery or trauma. Physical examination revealed abdominal distention, tenderness, and generalized rebound tenderness. Abdominal ultrasound revealed distention of the intestinal loops. Surgical exploration unveiled a congeni tal band constricting a jejunal loop. The band was subsequently removed, and the patient made a full recovery. Key clinical MessageThis case highlights the significance of maintaining clinical suspicion for CPBs in adults presenting with SBO. Early surgical intervention, ...
Source: Clinical Case Reports - March 14, 2024 Category: General Medicine Authors: Mouhammed Sleiay, Bilal Sleiay, Douha Albaroudi, Hasan Alsmoudi, Mohammad ali abshi, Mohammed Alaswad, Abdulazez Sleiay, Osama Arabi Tags: CASE REPORT Source Type: research

Identified PAH V230A and PAH V230I mutations in a family with diverse clinical presentations
In this study, we report an asymptomatic adult with mHPA who had never taken any medical intervention to control or lower her serum phenylalanine level (Phe). She had 179 μmol/L serum phenylalanine level and carried p.[V230A];[V230I] genotype. Her child was affected with phenylketonuria and had p.[V230A];[V230A] g enotype. Both pathogenic variants detected in the asymptomatic adult with mHPA were computationally analyzed to assess their pathogenicity and the p.V230I pathogenic variant was demonstrated to be responsible for the mHPA phenotype in the asymptomatic adult detected in this study. The findings in th is study c...
Source: Clinical Case Reports - March 13, 2024 Category: General Medicine Authors: Faeze Khaghani, Peyman Eshraghi, Tayebeh Hamzehloei Tags: CASE REPORT Source Type: research

Gastric sarcoidosis diagnosed with endoscopic ultrasound
We report the case of a 46-year-old African American female who experienced chronic epigastric abdominal pain, recurrent nausea, vomiting, and diarrhea for 15  years. Despite extensive investigations, including multiple biopsies, she was misdiagnosed with cyclic vomiting syndrome. Subsequently, an endoscopic ultrasound (EUS) revealed prominent lymph nodes and gastric granulomas, leading to a diagnosis of GS. This case underscores the importance of consi dering sarcoidosis in patients with refractory abdominal symptoms and highlights the utility of EUS in diagnosing this rare condition. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 13, 2024 Category: General Medicine Authors: Husam El  Sharu, Stephanie Ibarra, Ammad Chaudhary, Sinda Hidri, Zarak Khan, Danielle Hoo‐Fatt Tags: CASE REPORT Source Type: research