Successful curative treatment for a ruptured pancreatic acinar cell carcinoma by radical resection following modified FOLFIRINOX: a case report and literature review
AbstractPancreatic acinar cell carcinoma (PACC) is a rare pancreatic tumor type, and ruptured pancreatic tumors are rarer. Computed tomography (CT) in a 48-year-old man incidentally revealed a raptured pancreatic tail tumor. The patient was treated conservatively because he was asymptomatic, and his general condition was stable. After a detailed examination, the pancreatic tumor was diagnosed as raptured PACC. Considering the potential infiltration of tumor cells into the hematoma within the omental sac, our decision is to initiate chemotherapy as the primary course of action. A liquid biopsy was performed, and comprehensi...
Source: International Cancer Conference Journal - April 22, 2024 Category: Cancer & Oncology Source Type: research
Cancers, Vol. 16, Pages 1601: Treatment of Gastric Cancer Means Surgery, but Not Surgery Alone
Rausei
Despite numerous studies, gastric cancer (GC) still presents a high mortality rate in Eastern and Western countries, increasing attention for new therapeutic strategies [...] (Source: Cancers)
Source: Cancers - April 22, 2024 Category: Cancer & Oncology Authors: Manrica Fabbi Christina D. Bali Georgios D. Lianos Stefano Rausei Tags: Editorial Source Type: research
Impact of a board certification system and adherence to the clinical practice guidelines for gastric cancer on risk-adjusted surgical mortality after distal and total gastrectomy in Japan: a questionnaire survey of departments registered in the National Clinical Database
ConclusionsMultiple structural and process QIs are associated with surgical mortality after gastrectomy in Japan. Measuring and visualizing QIs may enhance healthcare improvements. (Source: Surgery Today)
Source: Surgery Today - April 21, 2024 Category: Surgery Source Type: research
Fusobacterium nucleatum carcinogenesis and drug delivery interventions
This article presents a comprehensive review of microbial communities especially F. nucleatum in tumor tissue, exploring their roles and underlying mechanisms in tumor development, treatment, and prevention. When the tumor-associated F. nucleatum is killed, the host immune response is activated to recognize tumor cells. Bacteria epitopes restricted by the host antigens, can be identified for future anti-bacteria/tumor vaccine development.PMID:38643839 | DOI:10.1016/j.addr.2024.115319 (Source: Advanced Drug Delivery Reviews)
Source: Advanced Drug Delivery Reviews - April 21, 2024 Category: Drugs & Pharmacology Authors: Zhenzhen Chen Leaf Huang Source Type: research
Usefulness of the C-Reactive Protein (CRP)-Albumin-Lymphocyte (CALLY) Index as a Prognostic Indicator for Patients With Gastric Cancer
CONCLUSIONS: The CALLY index may be associated with a poor prognosis for gastric cancer, highlighting the utility of a comprehensive assessment using inflammatory, nutritional, and immunological statuses.PMID:38644521 | DOI:10.1177/00031348241248693 (Source: The American Surgeon)
Source: The American Surgeon - April 21, 2024 Category: Surgery Authors: Keigo Nakashima Koichiro Haruki Teppei Kamada Junji Takahashi Masashi Tsunematsu Hironori Ohdaira Kenei Furukawa Yutaka Suzuki Toru Ikegami Source Type: research
Evaluation of expression level of BANCR, MALAT1 and FER1L4 and their target genes in coumarin-treated AGS cell line
In this study, we investigated the expression level of selected cellular lncRNAs (BANCR, MALAT1 and FER1L4) and their target genes (PTEN, p-PI3K and p-AKT) in coumarin-treated AGS cell line. The expressions of the three lncRNAs: BANCR, MALAT1 and FER1L4, as well as their specified targets, PTEN, PI3K and AKT, were measured by qRT-PCR. To gauge the impact of coumarin on the AGS cells, a MTT assay was utilized. A Western blot has been employed to assess variations in PTEN, p-PI3K, and p-AKT expression. The experiment's results showed that AGS viability diminished with increasing doses of coumarin. Compared to the control cel...
Source: Pathology, Research and Practice - April 21, 2024 Category: Pathology Authors: Shirin Shafaee Arani Majid Nejati Sepide Rastgoufar Arash Raisi Reza Eshraghi Amirreza Ostadian Amir Hassan Matini Neda Rahimain Hamed Mirzaei Source Type: research
Fusobacterium nucleatum carcinogenesis and drug delivery interventions
This article presents a comprehensive review of microbial communities especially F. nucleatum in tumor tissue, exploring their roles and underlying mechanisms in tumor development, treatment, and prevention. When the tumor-associated F. nucleatum is killed, the host immune response is activated to recognize tumor cells. Bacteria epitopes restricted by the host antigens, can be identified for future anti-bacteria/tumor vaccine development.PMID:38643839 | DOI:10.1016/j.addr.2024.115319 (Source: Advanced Drug Delivery Reviews)
Source: Advanced Drug Delivery Reviews - April 21, 2024 Category: Drugs & Pharmacology Authors: Zhenzhen Chen Leaf Huang Source Type: research
Application of Deep Learning Model and Machine Learning Detection Algorithm for Gastric Cancer Patients Undergoing Chemotherapy
(Source: Journal of Biomedical Nanotechnology)
Source: Journal of Biomedical Nanotechnology - April 20, 2024 Category: Nanotechnology Authors: Huang, Xiaohui Fu, Jing Wang, Xiaoyan Yu, Chaoxiu Tags: research-article Source Type: research
Discovery of YS-1 as a cell line of gastric inflammatory cancer-associated fibroblasts
CONCLUSIONS: YS-1 is a stable cell line of gastric iCAFs. This discovery will promote further research on iCAFs for many researchers.PMID:38642200 | DOI:10.1007/s11033-024-09442-4 (Source: Molecular Medicine)
Source: Molecular Medicine - April 20, 2024 Category: Molecular Biology Authors: Satoe Numakura Masahiro Kato Hiroshi Uozaki Source Type: research
Discovery of YS-1 as a cell line of gastric inflammatory cancer-associated fibroblasts
CONCLUSIONS: YS-1 is a stable cell line of gastric iCAFs. This discovery will promote further research on iCAFs for many researchers.PMID:38642200 | DOI:10.1007/s11033-024-09442-4 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 20, 2024 Category: Molecular Biology Authors: Satoe Numakura Masahiro Kato Hiroshi Uozaki Source Type: research
Characteristics and outcomes of cancer patients admitted to intensive care units in cancer specialized hospitals in China
CONCLUSION: Patients with lung cancer require more ICU care due to critical complications and the overall survival prognosis is poor. Colorectal cancer may benefit more from ICU management. This information may be considered in ICU admission and treatment strategies.PMID:38642154 | PMC:PMC11032264 | DOI:10.1007/s00432-024-05727-0 (Source: Clinical Colorectal Cancer)
Source: Clinical Colorectal Cancer - April 20, 2024 Category: Cancer & Oncology Authors: Wensheng Liu Dongmin Zhou Li Zhang Mingguang Huang Rongxi Quan Rui Xia Yong Ye Guoxing Zhang Zhuping Shen Cancer Critical Care Medicine Committee of the Chinese Anti-Cancer Association Source Type: research
Characteristics and outcomes of cancer patients admitted to intensive care units in cancer specialized hospitals in China
CONCLUSION: Patients with lung cancer require more ICU care due to critical complications and the overall survival prognosis is poor. Colorectal cancer may benefit more from ICU management. This information may be considered in ICU admission and treatment strategies.PMID:38642154 | PMC:PMC11032264 | DOI:10.1007/s00432-024-05727-0 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - April 20, 2024 Category: Cancer & Oncology Authors: Wensheng Liu Dongmin Zhou Li Zhang Mingguang Huang Rongxi Quan Rui Xia Yong Ye Guoxing Zhang Zhuping Shen Cancer Critical Care Medicine Committee of the Chinese Anti-Cancer Association Source Type: research
Primary thromboprophylaxis in cancer outpatients – real-world evidence
ConclusionPrimary thromboprophylaxis in medium-to-high-risk cancer outpatients is a safe and effective practice in real-world settings. This study is the first Portuguese RWE on primary thromboprophylaxis, highlighting evidence for improving prophylactic strategies in this population.Graphical abstract (Source: Journal of Thrombosis and Thrombolysis)
Source: Journal of Thrombosis and Thrombolysis - April 20, 2024 Category: Hematology Source Type: research
Integrated clinical and genomic models using machine-learning methods to predict the efficacy of paclitaxel-based chemotherapy in patients with advanced gastric cancer
Paclitaxel is commonly used as a second-line therapy for advanced gastric cancer (AGC). The decision to proceed with second-line chemotherapy and select an appropriate regimen is critical for vulnerable patien... (Source: BMC Cancer)
Source: BMC Cancer - April 20, 2024 Category: Cancer & Oncology Authors: Yonghwa Choi, Jangwoo Lee, Keewon Shin, Ji Won Lee, Ju Won Kim, Soohyeon Lee, Yoon Ji Choi, Kyong Hwa Park and Jwa Hoon Kim Tags: Research Source Type: research
Characteristics and outcomes of cancer patients admitted to intensive care units in cancer specialized hospitals in China
ConclusionPatients with lung cancer require more ICU care due to critical complications and the overall survival prognosis is poor. Colorectal cancer may benefit more from ICU management. This information may be considered in ICU admission and treatment strategies. (Source: Journal of Cancer Research and Clinical Oncology)
Source: Journal of Cancer Research and Clinical Oncology - April 20, 2024 Category: Cancer & Oncology Source Type: research
