Laparoscopic versus open repair for inguinal hernia in children: a retrospective cohort study
AbstractPurposeWe compared the outcomes of laparoscopic surgery (LS) with those of open surgery (OS) for unilateral and bilateral pediatric inguinal hernia.MethodsUsing a nationwide claim-based database in Japan, we analyzed data from children younger than 15  years old, who underwent inguinal hernia repair between January 2005 and December 2017. Patient characteristics, incidence of reoperation, postoperative complications, length of hospital stay, and duration of anesthesia were compared between LS and OS for unilateral and bilateral hernia.ResultsAmong 5554 patients, 2057 underwent LS (unilateral 1095, bilateral 96...
Source: Surgery Today - July 16, 2019 Category: Surgery Source Type: research

Changes in the rate of and trends in colectomy for ulcerative colitis during the era of biologics and calcineurin inhibitors based on a Japanese nationwide cohort study
AbstractPurposeWe evaluated the recent incidence of surgery and the changing surgery trends for ulcerative colitis (UC) in Japan due to the increasing use of anti-tumor necrosis factor (TNF) agents.MethodsA questionnaire survey was performed to assess the number of surgeries, surgical indications, surgical timing, and immunosuppressive treatments before surgery between 2007 and 2017.ResultsA total of 3801 surgical cases were reported over 11  years. The prevalence of UC surgery decreased over the period studied. The rate of prednisolone (PSL) use did not change. The prevalence of both calcineurin inhibitors (CNIs) and...
Source: Surgery Today - July 15, 2019 Category: Surgery Source Type: research

Association of skeletal muscle loss with the long-term outcomes of esophageal cancer patients treated with neoadjuvant chemotherapy
AbstractPurposeTo investigate the change in skeletal muscle mass and evaluate the prognostic impact of sarcopenia on esophageal cancer (EC) patientsMethodsThe subjects of this retrospective study were 90 EC patients who were treated with neoadjuvant chemotherapy (NAC) and subsequent esophagectomy. The skeletal muscle index (SMI) was defined according to computed tomography (CT) imaging of the total cross-sectional muscle tissue, measured at the third lumbar level using a volume analyzer before NAC and surgery. The SMI was calculated by normalization according to height, and skeletal muscle loss (SML) was defined as (pre-NA...
Source: Surgery Today - July 15, 2019 Category: Surgery Source Type: research

Reply to comment on “Ambiguity about the volume of colloids administration in a clinical study of thoracic esophagectomy precludes conclusion on renal safety of hydroxyethyl starch”
(Source: Surgery Today)
Source: Surgery Today - July 15, 2019 Category: Surgery Source Type: research

True esophagogastric junction adenocarcinoma: background of its definition and current surgical trends
AbstractThe definition of true esophagogastric junction (EGJ) adenocarcinoma and its surgical treatment are debatable. We review the basis for the current definition and the Japanese surgical strategy in managing true EGJ adenocarcinoma. The Siewert classification is a well-known anatomical classification system for EGJ adenocarcinomas: type II tumors in the region 1  cm above and 2 cm below the EGJ are described as “true carcinoma of the cardia”. Coincidentally, this range matches gastric cardiac gland distribution. Conversely, Nishi’s classification is generally used to describe EGJ carcinomas...
Source: Surgery Today - July 5, 2019 Category: Surgery Source Type: research

Collagen gel droplet-embedded culture drug sensitivity test (CD-DST) predicts the effect of adjuvant chemotherapy on pancreatic cancer
AbstractPurposeWe evaluated the clinical effectiveness of collagen gel droplet-embedded culture drug sensitivity tests (CD-DSTs) in predicting the efficacy of adjuvant chemo-therapeutic treatments for pancreatic cancer (PC).MethodsThe clinicopathological characteristics and prognoses of 22 PC patients who underwent CD-DST after pancreatectomy at Tohoku University between 2012 and 2016 were analyzed retrospectively. Eligibility criteria were resectable or borderline resectable PC, successful evaluation for 5-fluorouracil sensitivity by CD-DST, treatment with S-1 adjuvant chemotherapy, and no preoperative chemotherapy.Result...
Source: Surgery Today - July 2, 2019 Category: Surgery Source Type: research

End-to-end intestinal anastomosis using a novel biodegradable stent for laparoscopic colonic surgery: a multicenter study
AbstractPurposeOur animal studies have demonstrated the safety and feasibility of end-to-end intestinal anastomosis using a stent for laparoscopic colonic surgery. Therefore, we designed a non-inferiority trial to investigate the outcomes of stent anastomosis (SA) vs. those of conventional hand-sewn anastomosis (CA).MethodsA multicenter randomized controlled trial was conducted between December, 2016 and April, 2018. The primary outcome was the healing condition of the anastomoses, evaluated by endoscopy 6  months postoperatively. The secondary outcomes were the anastomotic completion time, anastomotic leak, intestina...
Source: Surgery Today - June 29, 2019 Category: Surgery Source Type: research

The short-term outcomes of laparoscopic –endoscopic cooperative surgery for colorectal tumors (LECS-CR) in cases involving endoscopically unresectable colorectal tumors
ConclusionOur results indicated that LECS is a safe and feasible technique that results in high-quality colorectal polyp resection with quicker recovery and favorable 30-days postoperative outcomes. (Source: Surgery Today)
Source: Surgery Today - June 27, 2019 Category: Surgery Source Type: research

Prone “computed tomography hernia study” for the diagnosis of inguinal hernia
ConclusionThe CT hernia study appears to provide a high detection rate and makes differentiating the various types of inguinal hernia possible. We believe our CT hernia study adds a level of objectivity that is diagnostically beneficial. (Source: Surgery Today)
Source: Surgery Today - June 26, 2019 Category: Surgery Source Type: research

Indications for resection and perioperative outcomes of surgery for pancreatic neuroendocrine neoplasms in Germany: an analysis of the prospective DGAV StuDoQ|Pancreas registry
This study evaluated the current practice of pNEN surgery across Germany, including its adherence with guidelines and its perioperative outcomes.MethodsPatients who underwent surgery for pNENs (April 2013 –June 2017) were retrieved from the prospective StuDoQ|Pancreas registry of the German Society of General and Visceral Surgery and retrospectively analyzed.ResultsA total of 287 patients (53.7% male) with a mean age of 59.2  ± 14.2 years old underwent pancreatic resection for pNENs. Tumors were localized in the pancreatic head (40.4%), body (23%), or tail (36.6%). A total of 239 (83.3%) pat...
Source: Surgery Today - June 25, 2019 Category: Surgery Source Type: research

Is laparoscopic colorectal surgery with continuation of antiplatelet therapy safe without increasing bleeding complications?
ConclusionIn a case-matched comparison, continuation of aspirin during laparoscopic colorectal surgery did not increase perioperative complications. In laparoscopic colorectal surgery, continuation of aspirin is an acceptable strategy for patients with thromboembolic risk caused by interruption of APT. (Source: Surgery Today)
Source: Surgery Today - June 22, 2019 Category: Surgery Source Type: research

Laparoscopic esophagogastrostomy using a knifeless linear stapler after proximal gastrectomy
AbstractProximal gastrectomy should improve the late postoperative function in patients with gastric cancer located in the upper third of the stomach or esophagogastric junction. However, a standard method of esophagogastrostomy has not been established for improving the postoperative function. To prevent reflux and stenosis following proximal gastrectomy, we introduced a novel esophagogastrostomy method using a knifeless linear stapler. The stapler was inserted into holes created in both the esophagus and remnant stomach and fired proximally. A 1.5-cm incision was made from the edge of the entry hole between the staples. ...
Source: Surgery Today - June 20, 2019 Category: Surgery Source Type: research

The impact of cervical lymph node dissection on acid and duodenogastroesophageal reflux after intrathoracic esophagogastrostomy following transthoracic esophagectomy
ConclusionCervical lymph node dissection increases acid reflux and DGER and can lead to an increase in the incidence of reflux esophagitis in patients undergoing intrathoracic esophagogastrostomy. (Source: Surgery Today)
Source: Surgery Today - June 19, 2019 Category: Surgery Source Type: research

Standard protocol devised by the Japanese Pediatric Impedance Working Group for combined multichannel intraluminal impedance-pH measurements in children
AbstractMultichannel intraluminal impedance-pH measurements (MII-pH) are useful for evaluating acid and non-acid gastroesophageal reflux (GER). However, the use of MIH-pH is not yet established in Japan. The Japanese Pediatric Impedance Working Group (Japanese-PIG) convened to devise a standard protocol for MII-pH in Japanese children. The expert members of the Japanese-PIG collected data on pediatric MII-pH from the relevant literature in English, including the standard protocol of MII-pH presented by the European PIG, and the insights of international experts. The resultant consensus was included in the contents of the s...
Source: Surgery Today - June 18, 2019 Category: Surgery Source Type: research

The quality of life after laparoscopic ventral and incisional hernia repair with closure and non-closure of fascial defect
ConclusionsLVIHR improved the QOL, regardless of defect closure. (Source: Surgery Today)
Source: Surgery Today - June 15, 2019 Category: Surgery Source Type: research

Recombinant human soluble thrombomodulin reduces the severity and incidence of necrotizing enterocolitis in a newborn rat model
ConclusionsOur experimental study showed that rTM is able to reduce the severity and incidence of NEC. It may be an alternative option for the treatment of NEC. (Source: Surgery Today)
Source: Surgery Today - June 12, 2019 Category: Surgery Source Type: research

Hormone receptor, human epidermal growth factor receptor-2, and Ki-67 status in primary breast cancer and corresponding recurrences or synchronous axillary lymph node metastases
AbstractThe therapeutic strategy for breast cancer is determined by the surrogate subtype, which is defined by biomarkers, such as estrogen receptor (ER), progesterone receptor (PgR), human epidermal growth factor receptor-2 (HER2), and Ki-67. In previous reports, the rate of discordance in ER, PgR, and HER2 between primary breast cancer and recurrent lesions or synchronous axillary lymph node metastasis was 15 –25, 25–40, and 5–25 or 7–50, 10–50, and 3–30%, respectively. Overall, hormone receptors tended to weaken during the metastatic process, while patterns of HER2 were not uniform. R...
Source: Surgery Today - June 12, 2019 Category: Surgery Source Type: research

Clinical- and surgery-specific risk factors for post-operative sepsis: a systematic review and meta-analysis of over 30 million patients
In conclusion, multiple-patient and surgery-related risk factors are associated with the development of post-operative sepsis. Recognizing these risk factors could assist in the pre-operative identification of patients at risk of post-operative sepsis. (Source: Surgery Today)
Source: Surgery Today - June 6, 2019 Category: Surgery Source Type: research

Effects of surgery on the patient-reported outcomes of primary hyperparathyroidism patients with mild hypercalcemia without classic symptoms: a systematic review of the literature
AbstractPurposeTo establish if parathyroidectomy is beneficial for patient-reported outcomes (PROs), including quality of life (QoL), of patients with mild hypercalcemia (  
Source: Surgery Today - June 5, 2019 Category: Surgery Source Type: research

Surgical intervention for ischemic mitral regurgitation: how can we achieve better outcomes?
AbstractIschemic mitral regurgitation (MR) is a common complication of myocardial infarction. Left ventricular (LV) dysfunction and distortion of the subvalvular apparatus are the main contributors to ischemic MR. Coronary artery bypass grafting alone, mitral valve replacement, and mitral valve repair, with or without subvalvular procedures, have been performed for moderate-to-severe ischemic MR. Several randomized studies on the surgical treatment of ischemic MR have been performed; however, the optimal surgical strategy remains controversial because none have demonstrated a clear survival benefit. Since the mechanisms of...
Source: Surgery Today - May 30, 2019 Category: Surgery Source Type: research

The prognostic significance of the comprehensive complication index in patients with gastric cancer
This study included 452 gastric adenocarcinoma patients who underwent curative surgery.ResultsThe CCI values were significantly higher in older patients (  ≥ 70 years;P 
Source: Surgery Today - May 30, 2019 Category: Surgery Source Type: research

Predictors of the response of operating room personnel to surgeon behaviors
ConclusionCharacteristics of operative personnel were correlated with varying tolerance of surgeon behaviors, with specific subgroups more critical of female surgeons than males. Further exploration of these perceptions will serve to improve interactions in a diverse workplace. (Source: Surgery Today)
Source: Surgery Today - May 29, 2019 Category: Surgery Source Type: research

Can rectal washout reduce anastomotic recurrence after anterior resection for rectal cancer? A review of the literature
AbstractLocal recurrence rates of rectal cancer after anterior resection remain high, despite the continued efforts of surgeons to devise preventive measures. Anastomotic recurrence, a form of local recurrence, may be caused by the implantation of exfoliated cancer cells during resection, and rectal stump washout has been proposed as a way to reduce the risk of this occurring. In this review article, we explore the mechanism of anastomotic recurrence after low anterior resection for rectal cancer, and examine the history and effectiveness of rectal washout on reducing recurrence rates, with a focus on washout solutions, pr...
Source: Surgery Today - May 27, 2019 Category: Surgery Source Type: research

The tumor doubling time is a useful parameter for predicting the histological type of thymic epithelial tumors
ConclusionsThe TDT is a useful parameter for differentiating between thymoma and thymic carcinoma group. (Source: Surgery Today)
Source: Surgery Today - May 27, 2019 Category: Surgery Source Type: research

A novel device designed to improve the operability of energy devices with foot pedals in endoscopic surgery: the Foot-Site Monitor
ConclusionsThe use of the FSM in endoscopic surgery contributes to reduced shaking of the forceps and may shorten the operative time. (Source: Surgery Today)
Source: Surgery Today - May 27, 2019 Category: Surgery Source Type: research

Efficiency of thoracoscopic palpation in localizing small pulmonary nodules
AbstractPurposeThe thoracoscopic localization of small and deep pulmonary nodules can be challenging. We conducted this study to evaluate the efficiency of thoracoscopic palpation in tumor detection.MethodsThe subjects of this study were 229 patients with a collective 267 indeterminate pulmonary nodules  ≤ 15 mm in diameter, in the outer third of the lung field. The nodules were localized by palpation using the forefinger or a metal suction probe. Based on the distance from the pleura-to-tumor size ratio (D/S), the nodules were classified into group A (D/S = 0), group B (0  &thins...
Source: Surgery Today - May 25, 2019 Category: Surgery Source Type: research

Verification of T descriptor with consolidation size for sub-centimeter non-small cell lung cancer
ConclusionsThere may be pathological and survival differences between cTis/cT1mi tumors and cT1a tumors, but not between cTis tumors and cT1mi tumors. (Source: Surgery Today)
Source: Surgery Today - May 22, 2019 Category: Surgery Source Type: research

Intracorporeal overlap gastro-gastrostomy for solo single-incision pylorus-preserving gastrectomy in early gastric cancer
This report discusses the technique of solo single-incision pylorus-preserving gastrectomy (SIPPG) for early gastric cancer. To overcome difficulties regarding lymph node dissection (LND), a scope holder and an energy device were used, allowing fine dissection in a fixed field of view. The overlap gastro-gastrostomy technique was used for anastomosis. Seventeen patients underwent solo SIPGG. The mean operation time was 150.1  ± 28.7 min, and no patients developed postoperative complications or delayed gastric emptying within 30 days of the operation. Using scope holders and performing fine di...
Source: Surgery Today - May 21, 2019 Category: Surgery Source Type: research

A snapshot of surgical resident training in Japan: results of a national-level needs assessment survey
ConclusionThis national-level needs assessment of surgical training in Japan identified several gaps in the curriculum. These results provide valuable data to assist the ongoing efforts for surgical residency curriculum improvement. (Source: Surgery Today)
Source: Surgery Today - May 17, 2019 Category: Surgery Source Type: research

Long-term outcomes of patch tracheoplasty using collagenous tissue membranes (biosheets) produced by in-body tissue architecture in a beagle model
ConclusionsBiosheets showed excellent performance as a scaffold for trachea regeneration with complete luminal epithelium and partial chondrocytes in a 1-year beagle implantation model of patch tracheoplasty. (Source: Surgery Today)
Source: Surgery Today - May 16, 2019 Category: Surgery Source Type: research

Score of the preoperative absolute number of lymphocytes, monocytes, and neutrophils as a prognostic indicator for patients with gastric cancer
AbstractPurposeThe association between the preoperative absolute neutrophil count (NC), lymphocyte count (LC), and monocyte count (MC) in the peripheral blood and the prognosis of gastric cancer (GC) patients has not been investigated widely.MethodsWe enrolled 445 patients who underwent surgery for GC between January, 2005 and April, 2013 to analyze the correlations among NC, LC, and MC and their prognoses.ResultsBased on cut-off values calculated by ROC analysis, patients were sub grouped as having: NC  ≥ 4477 (NCHigh), NC  
Source: Surgery Today - May 6, 2019 Category: Surgery Source Type: research

Laparoscopic extraperitoneal sigmoid colostomy using the totally extraperitoneal hernia repair technique after abdominoperineal resection for rectal cancer
We describe a new technique for laparoscopic extraperitoneal sigmoid colostomy following APR. After the rectus abdominis muscle is separated, Lap ProtectorTM and EZ AccessTM devices are placed. An extraperitoneal stoma tunnel is created laparoscopically as much as possible. Next, the peritoneum is separated from the inside of the abdominal cavity, and the extraperitoneal tunnel is opened. At the time of writing, we had performed laparoscopic extraperitoneal sigmoid colostomy in eight patients, without any complications or conversion to the conventional procedure. Thus, laparoscopic extraperitoneal sigmoid colostomy is a us...
Source: Surgery Today - May 2, 2019 Category: Surgery Source Type: research

A prospective multi-center registry concerning the clinical performance of laparoscopic colorectal surgery using an absorbable adhesion barrier (INTERCEED ® ) made of oxidized regenerated cellulose
ConclusionsUsing INTERCEED® in laparoscopic colorectal surgery is safe and may be useful for preventing postoperative adhesive small intestinal obstruction. (Source: Surgery Today)
Source: Surgery Today - April 29, 2019 Category: Surgery Source Type: research

Antimicrobial prophylaxis for 1 day versus 3 days in liver cancer surgery: a randomized controlled non-inferiority trial
ConclusionTo prevent SSI in liver cancer surgery, a 1-day regimen of flomoxef sodium is recommended for antimicrobial prophylaxis because of confirming the non-inferiority to longer usage. (Source: Surgery Today)
Source: Surgery Today - April 27, 2019 Category: Surgery Source Type: research

Perioperative body composition changes in the multimodal treatment of gastrointestinal cancer
AbstractSurgical resection and perioperative adjuvant therapy are widely accepted standard treatments for gastrointestinal cancer. However, body composition changes, such as weight loss and skeletal muscle loss, are unavoidable during these treatments. Several studies have shown that perioperative body composition changes are affected by multimodal treatment for gastrointestinal cancer. This review summarizes the background, current status, and future perspectives of perioperative body composition changes in the multimodal treatment of gastrointestinal cancer. Recent studies have described the body composition changes obse...
Source: Surgery Today - April 26, 2019 Category: Surgery Source Type: research

Treatment guidelines for persistent cloaca, cloacal exstrophy, and Mayer –Rokitansky–Küster–Häuser syndrome for the appropriate transitional care of patients
AbstractWe developed treatment guidelines (TGs) for appropriate transitional care of the genitourinary system in patients with persistent cloaca (PC), cloacal exstrophy (CE), or Mayer –Rokitansky–Küster–Häuser syndrome (MRKH). These TGs are in accordance with the Medical Information Network Distribution Service (Minds), published in 2014 in Japan. Clinical questions (CQs) concerning treatment outcomes of the genitourinary system, pregnancy and delivery, and quality of lif e in adulthood were prepared as six themes for PC and CE and five themes for MRKH. We were able to publish statements on chro...
Source: Surgery Today - April 22, 2019 Category: Surgery Source Type: research

Super-elderly patient-specific perioperative complications in breast cancer surgery
AbstractPurposeGeriatric surgery poses specific challenges due to patient vulnerability in relation to aging. We analyzed perioperative challenges concerning super-elderly patients with breast cancer.MethodsBetween 2013 and 2018, 908 patients with breast cancer were treated surgically. Of these, two patient groups were compared: Group A ( ≥ 85 years old,n = 34, 3.7%) and Group B (75–84 years old,n = 136, 15%).ResultsIn Groups A and B, 26.4% and 36.8% of patients lived alone, respectively. Group A patients had higher rates of psychiatric and cardiovascular disease (32.4%...
Source: Surgery Today - April 22, 2019 Category: Surgery Source Type: research

Serum procalcitonin as a predictor of infectious complications after pancreaticoduodenectomy: review of the literature and our experience
AbstractProcalcitonin (PCT) is an early predictor of bacterial infection. We reviewed the literature and analyzed data on our own patients to assess the value of PCT as a predictor of infectious complications after pancreaticoduodenectomy (PD). The relevant literature published up until November 30, 2018, was reviewed, with no publication date restrictions. Letters to the editor and studies lacking necessary data were excluded. We also reviewed, retrospectively, the medical records of 77 patients who underwent PD between January, 2011 and April, 2016 at our hospital, to evaluate infectious complications and laboratory resu...
Source: Surgery Today - April 16, 2019 Category: Surgery Source Type: research

Right anatomical hepatectomy: pioneers, evolution, and the future
AbstractTo identify the pioneers of right anatomical hepatectomy (RAH), and clarify the development of associated operative procedures, concepts, and the future, we reviewed the “hidden” literature published in Eastern and Western countries since the 1940s. We searched the English and non-English literature on RAH through web search engines, text books and documents, and also referred to experts’ comments. Non-English literature, other than in Japanese, was translated . Changes in the anatomical concept, anatomical identification, vascular control technique, approaches, pre-operative management, and other...
Source: Surgery Today - April 13, 2019 Category: Surgery Source Type: research

Long-term outcomes after an aggressive resection of adenosquamous carcinoma of the pancreas
AbstractPurposeAdenosquamous carcinoma (ASC) of the pancreas is a rare malignancy, associated with a poor prognosis after surgical resection, with reported median survival times (MSTs) ranging from 4.4 to 13.1  months. We conducted this study to investigate the long-term outcomes of patients after the resection for ASC.MethodsBetween 2002 and 2016, a total of 456 patients underwent resection for ASC or adenocarcinoma (AC) of the pancreas. ASC was confirmed in 17 (3.7%) of these patients. We analyzed the clinicopathological characteristics and survival of these 17 patients in comparison with those of patients with AC o...
Source: Surgery Today - April 12, 2019 Category: Surgery Source Type: research

Totally extraperitoneal approach to laparoscopic lateral lymph node dissection for patients with recurrent lateral pelvic lymph nodes after rectal cancer surgery: a novel technique —M TEP LLND
AbstractLateral lymph node dissection (LLND) for recurrence of lateral pelvic lymph node metastasis after rectal cancer surgery is technically demanding because of the need for re-do surgery. We herein report a novel technique of laparoscopic LLND via a totally extraperitoneal (TEP) approach. Since October 2018, we have performed LLND based on a TEP approach, called “M TEP LLND”, with two cases treated. By peeling in the caudal direction in the dorsal layer of the rectus abdominis muscle, a working space is created once the extraperitoneal space is reached, and LLND is performed. All lateral pelvic lymph node d...
Source: Surgery Today - April 10, 2019 Category: Surgery Source Type: research

A comparison between 2- and 3-dimensional approaches to solid component measurement as radiological criteria for sublobar resection in lung adenocarcinoma  ≤ 2 cm in size
ConclusionsA solid component  ≤ 5 mm in size is an appropriate criterion for sublobar resection for both measurements. In addition, 2D measurement is justified because of its simple implementation. (Source: Surgery Today)
Source: Surgery Today - April 9, 2019 Category: Surgery Source Type: research

Predicting mortality in patients admitted to the intensive care unit after open vascular surgery
AbstractPurposesVascular surgery (VS) has a higher perioperative mortality than other types of surgery. We compared different scores for predicting mortality in patients admitted to the intensive care unit (ICU) after open VS.MethodsPatients admitted to the ICU after open VS from 2006 to 2013 were included. We calculated the Acute Physiology and Chronic Health Evaluation (APACHE), Simplified Acute Physiology Score (SAPS), Physiological and Operative Severity Score for the enUmeration of Mortality and Morbidity (POSSUM) and Preoperative Score to Predict Postoperative Mortality (POSPOM). We performed multivariate logistic re...
Source: Surgery Today - April 9, 2019 Category: Surgery Source Type: research

Prognostic predictions based on pathological findings of peritoneal dissemination in patients with stage IV colorectal cancer without residual disease (R0 status)
This study aimed to clarify the prognosis of patients after resection of stage IV colorectal cancer and synchronous peritoneal metastasis (no residual disease: R0 status) based on histopathologic findings.MethodsThe subjects of this study were 26 patients who underwent radical resection of synchronous peritoneal metastases of stage IV colorectal cancer. Only patients with one synchronous peritoneal metastasis were included in this study. The peritoneal lesions were initially classified into two categories based on the presence or absence of adenocarcinoma on their surface: RM-negative or RM-positive. The lesions were subse...
Source: Surgery Today - April 8, 2019 Category: Surgery Source Type: research

A novel dual-covering method in video-assisted thoracic surgery for pediatric primary spontaneous pneumothorax
ConclusionThe DC method prevented the recurrence of PSP more effectively than the SC method after VATS in pediatric patients. Long-term follow-up after VATS for pediatric PSP is also important because of the risk of delayed recurrence. (Source: Surgery Today)
Source: Surgery Today - April 6, 2019 Category: Surgery Source Type: research

A Japanese multicenter phase II study of adjuvant chemotherapy with mFOLFOX6/CAPOX for stage III colon cancer treatment after D2/D3 lymphadenectomy
AbstractPurposeA phase II trial was conducted to investigate the benefit of oxaliplatin-based adjuvant chemotherapy in Japanese stage III colon cancer patients.MethodsEligible patients were scheduled to receive 12 cycles of mFOLFOX6 or 8 cycles of CAPOX in adjuvant settings. The primary endpoint was the 3-year disease-free survival (DFS). Cox proportional hazards regression was performed to identify risk factors for a worse DFS.ResultsA total of 130 patients, including 73 patients receiving mFOLFOX6 and 57 patients receiving CAPOX, were enrolled from 16 institutions between April 2010 and April 2014. The 3-year DFS was 82....
Source: Surgery Today - April 5, 2019 Category: Surgery Source Type: research

Conversion surgery for initially unresectable pancreatic cancer: current status and unresolved issues
AbstractPancreatic cancer is one of the most lethal of all malignancies. One of the reasons for the dismal prognosis is that most diagnoses are made when the disease is either locally advanced or metastatic. Recent advances in chemotherapy and chemoradiotherapy (CRT) enable “conversion surgery” to be performed for selected patients with initially unresectable pancreatic cancer following favorable responses to preoperative treatment. Using FOLFIRINOX as preoperative treatment, the resection rate was reported as 6–44% of patients with locally advanced cancer and th e prognosis of these patients was favorabl...
Source: Surgery Today - April 4, 2019 Category: Surgery Source Type: research

Etiology and management of low anterior resection syndrome based on the normal defecation mechanism
AbstractLow anterior resection syndrome (LARS) commonly develops after an anal sphincter-preserving operation (SPO). The etiology of LARS is not well understood, as the anatomical components and physiological function of normal defecation, which may be damaged during the SPO, are not well established. SPOs may damage components of the anal canal (such as the internal anal sphincter, longitudinal conjoint muscle, or hiatal ligament), either mechanically or via injury to the nerves that supply these organs. The function of the rectum is substantially impaired by resection of the rectum, division of the rectococcygeus muscle,...
Source: Surgery Today - April 1, 2019 Category: Surgery Source Type: research

Surgical outcome of pulmonary artery reconstruction using the expanded polytetrafluoroethylene patch in patients with lung cancer
ConclusionPatch angioplasty using the ePTFE sheet is a reliable procedure in radical surgery for lung cancer. (Source: Surgery Today)
Source: Surgery Today - April 1, 2019 Category: Surgery Source Type: research

Feasibility of neoadjuvant therapy for elderly patients with locally advanced rectal cancer
ConclusionsNeoadjuvant therapy was feasible and should be considered as a treatment option for carefully selected elderly patients with locally advanced low rectal cancer. (Source: Surgery Today)
Source: Surgery Today - April 1, 2019 Category: Surgery Source Type: research