YTHDF1 regulates immune cell infiltration in gastric cancer via interaction with p53
In conclusion, the findings of the present study indicate that YTHDF1 is associated with a poor prognosis and serves an important role in the TME of GC. We hypothesize, for the first time to the best of our knowledge, that YTHDF1 regulates immune cell infiltration by interacting with p53 in GC, which provides a promising direction for future research.PMID:38682111 | PMC:PMC11046265 | DOI:10.3892/etm.2024.12543 (Source: Experimental and Therapeutic Medicine)
Source: Experimental and Therapeutic Medicine - April 29, 2024 Category: General Medicine Authors: Quan Liao Jianping Xiong Source Type: research
Characteristics of early gastric tumors with different differentiation and predictors of long-term outcomes after endoscopic submucosal dissection
CONCLUSION: Differentiations of gastric mucosal tumors have different epidemiological and endoscopic characteristics, which are closely related to the safety and efficacy of ESD.PMID:38681129 | PMC:PMC11045489 | DOI:10.3748/wjg.v30.i14.1990 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 29, 2024 Category: Gastroenterology Authors: Hong-Yi Zhu Jie Wu Yuan-Miao Zhang Fang-Lan Li Jin Yang Bin Qin Jiong Jiang Ning Zhu Meng-Yao Chen Bai-Cang Zou Source Type: research
Topic highlight on texture and color enhancement imaging in gastrointestinal diseases
In conclusion, TXI can improve gastrointestinal lesion detection and qualitative diagnosis. Therefore, further studies on the efficacy of TXI in clinical practice are required.PMID:38681121 | PMC:PMC11045492 | DOI:10.3748/wjg.v30.i14.1934 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 29, 2024 Category: Gastroenterology Authors: Osamu Toyoshima Toshihiro Nishizawa Keisuke Hata Source Type: research
Characteristics of early gastric tumors with different differentiation and predictors of long-term outcomes after endoscopic submucosal dissection
CONCLUSION: Differentiations of gastric mucosal tumors have different epidemiological and endoscopic characteristics, which are closely related to the safety and efficacy of ESD.PMID:38681129 | PMC:PMC11045489 | DOI:10.3748/wjg.v30.i14.1990 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Hong-Yi Zhu Jie Wu Yuan-Miao Zhang Fang-Lan Li Jin Yang Bin Qin Jiong Jiang Ning Zhu Meng-Yao Chen Bai-Cang Zou Source Type: research
Topic highlight on texture and color enhancement imaging in gastrointestinal diseases
In conclusion, TXI can improve gastrointestinal lesion detection and qualitative diagnosis. Therefore, further studies on the efficacy of TXI in clinical practice are required.PMID:38681121 | PMC:PMC11045492 | DOI:10.3748/wjg.v30.i14.1934 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Osamu Toyoshima Toshihiro Nishizawa Keisuke Hata Source Type: research
Ethnopharmacological uses of fauna among the people of central Punjab, Pakistan
This study focuses on investigating the utilization of animal-based traditional medicine by the people of Pakistan, specifically in the Gujranwala area.METHODS: Data collection took place from January to September 2019 through interviews with local communities. Ethnomedicinal applications of animal products were analyzed using several indices, including Relative Frequency of Citation (RFC), Relative Popularity Level (RPL), Folk Use Value (FL), and Relative Occurrence Percentage (ROP).RESULTS: The study identified the use of different body parts of 54 species of animals in treating various diseases and health issues. These ...
Source: Herpes - April 29, 2024 Category: Infectious Diseases Authors: Abdul Majid Khan Muhammad Altaf Tanveer Hussain M Haroon Hamed Umaira Safdar Amina Ayub Zaibun-Nisa Memon Adnan Hafiz Sana Ashraf Muhammad Shoaib Amjad Muhammad Majeed Musheerul Hassan Rainer W Bussmann Arshad Mahmood Abbasi Mohamed Al-Yafrsi Hosam O Elan Source Type: research
Exploring new frontiers: cell surface vimentin as an emerging marker for circulating tumor cells and a promising therapeutic target in advanced gastric Cancer
CONCLUSION: In summary, leveraging CSV as a universal CTCs marker represents a significant breakthrough in advancing personalized medicine for patients with advanced GC. This research not only paves the way for tailored therapeutic strategies but also underscores the pivotal role of CSV in enhancing GC management, opening new frontiers for precision medicine.PMID:38685125 | DOI:10.1186/s13046-024-03043-6 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - April 29, 2024 Category: Cancer & Oncology Authors: Heming Li Yang-Zhuangzhuang Zhu Lu Xu Tao Han Jiasi Luan Xin Li Yuting Liu Zhi Wang Qiuge Liu Xiangyu Kong Chunpu Zou Lin Su Yifei Hou Xiao Chen Lujun Chen Ruoyu Wang Zihang Xu Mingfang Zhao Source Type: research
Critical updates in neuroendocrine tumors: Version 9 American Joint Committee on Cancer staging system for gastroenteropancreatic neuroendocrine tumors
CA Cancer J Clin. 2024 Apr 29. doi: 10.3322/caac.21840. Online ahead of print.ABSTRACTThe American Joint Committee on Cancer (AJCC) staging system for all cancer sites, including gastroenteropancreatic neuroendocrine tumors (GEP-NETs), is meant to be dynamic, requiring periodic updates to optimize AJCC staging definitions. This entails the collaboration of experts charged with evaluating new evidence that supports changes to each staging system. GEP-NETs are the second most prevalent neoplasm of gastrointestinal origin after colorectal cancer. Since publication of the AJCC eighth edition, the World Health Organization has ...
Source: Clinical Colorectal Cancer - April 29, 2024 Category: Cancer & Oncology Authors: Aman Chauhan Kelley Chan Thorvardur R Halfdanarson Andrew M Bellizzi Guido Rindi Dermot O'Toole Phillip S Ge Dhanpat Jain Arvind Dasari Daniel A Anaya Emily Bergsland Erik Mittra Alice C Wei Thomas A Hope Ayse T Kendi Samantha M Thomas Sherlonda Flem Jame Source Type: research
The Role of Delirium on Short- and Long-Term Postoperative Outcomes Following Major Gastrointestinal Surgery for Cancer
CONCLUSIONS: Postoperative delirium occurred in one in 50 patients undergoing surgical resection of a digestive tract cancer. Delirium was linked to a reduced likelihood of achieving an optimal postoperative outcome, increased ICU utilization, higher expenditures, and a worse long-term prognosis. Initiatives to prevent delirium are vital to improve postoperative outcomes among cancer surgery patients.PMID:38683304 | DOI:10.1245/s10434-024-15358-x (Source: Ann Oncol)
Source: Ann Oncol - April 29, 2024 Category: Cancer & Oncology Authors: Erryk S Katayama Hunter Stecko Selamawit Woldesenbet Mujtaba Khalil Muhammad Musaab Munir Yutaka Endo Diamantis Tsilimigras Timothy M Pawlik Source Type: research
Chronological Trend of Opportunistic Endoscopic Screening for Gastric Cancer and Atrophic Gastritis
CONCLUSIONS: The gastric cancer detection rate and atrophic gastritis prevalence have decreased over time. However, continuing endoscopic screening is important, especially for those at a high risk of developing gastric cancer complicated by severe atrophic gastritis.PMID:38679984 | DOI:10.31557/APJCP.2024.25.4.1247 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Keiko Nakamura Yasuo Kakukgawa Masau Sekiguchi Eriko So Tsuruki Minori Matsumoto Izumi Hisada Yasuhiko Mizuguchi Hiroyuki Takamaru Taku Sakamoto Yutaka Saito Nozomu Kobayashi Takahisa Matsuda Source Type: research
Exploring new frontiers: cell surface vimentin as an emerging marker for circulating tumor cells and a promising therapeutic target in advanced gastric Cancer
CONCLUSION: In summary, leveraging CSV as a universal CTCs marker represents a significant breakthrough in advancing personalized medicine for patients with advanced GC. This research not only paves the way for tailored therapeutic strategies but also underscores the pivotal role of CSV in enhancing GC management, opening new frontiers for precision medicine.PMID:38685125 | DOI:10.1186/s13046-024-03043-6 (Source: Cell Research)
Source: Cell Research - April 29, 2024 Category: Cytology Authors: Heming Li Yang-Zhuangzhuang Zhu Lu Xu Tao Han Jiasi Luan Xin Li Yuting Liu Zhi Wang Qiuge Liu Xiangyu Kong Chunpu Zou Lin Su Yifei Hou Xiao Chen Lujun Chen Ruoyu Wang Zihang Xu Mingfang Zhao Source Type: research
FANCA facilitates G1/S cell cycle advancement, proliferation, migration and invasion in gastric cancer
Acta Biochim Biophys Sin (Shanghai). 2024 Apr 29. doi: 10.3724/abbs.2024045. Online ahead of print.ABSTRACTThe present study explores the function of FANCA gene, a pivotal member of the Fanconi anaemia (FA) pathway crucial for preserving genomic stability and preventing cancer, particularly in the context of gastric cancer (GC). Using immunohistochemistry, quantitative real-time PCR, and western blot analysis, we evaluate FANCA mRNA and protein expressions in GC cell lines. The relationship between FANCA expression and clinicopathological characteristics is also explored. Various assays, including CCK8, colony formation, w...
Source: Acta Biochimica et Biophysica Sinica - April 29, 2024 Category: Biochemistry Authors: Wei Wang Shantanu Baral Bin Liu Qiannan Sun Liuhua Wang Jun Ren Dong Tang Daorong Wang Source Type: research
YTHDF1 regulates immune cell infiltration in gastric cancer via interaction with p53
In conclusion, the findings of the present study indicate that YTHDF1 is associated with a poor prognosis and serves an important role in the TME of GC. We hypothesize, for the first time to the best of our knowledge, that YTHDF1 regulates immune cell infiltration by interacting with p53 in GC, which provides a promising direction for future research.PMID:38682111 | PMC:PMC11046265 | DOI:10.3892/etm.2024.12543 (Source: Experimental and Therapeutic Medicine)
Source: Experimental and Therapeutic Medicine - April 29, 2024 Category: General Medicine Authors: Quan Liao Jianping Xiong Source Type: research
Ethnopharmacological uses of fauna among the people of central Punjab, Pakistan
This study focuses on investigating the utilization of animal-based traditional medicine by the people of Pakistan, specifically in the Gujranwala area.METHODS: Data collection took place from January to September 2019 through interviews with local communities. Ethnomedicinal applications of animal products were analyzed using several indices, including Relative Frequency of Citation (RFC), Relative Popularity Level (RPL), Folk Use Value (FL), and Relative Occurrence Percentage (ROP).RESULTS: The study identified the use of different body parts of 54 species of animals in treating various diseases and health issues. These ...
Source: Herpes - April 29, 2024 Category: Infectious Diseases Authors: Abdul Majid Khan Muhammad Altaf Tanveer Hussain M Haroon Hamed Umaira Safdar Amina Ayub Zaibun-Nisa Memon Adnan Hafiz Sana Ashraf Muhammad Shoaib Amjad Muhammad Majeed Musheerul Hassan Rainer W Bussmann Arshad Mahmood Abbasi Mohamed Al-Yafrsi Hosam O Elan Source Type: research
Characteristics of early gastric tumors with different differentiation and predictors of long-term outcomes after endoscopic submucosal dissection
CONCLUSION: Differentiations of gastric mucosal tumors have different epidemiological and endoscopic characteristics, which are closely related to the safety and efficacy of ESD.PMID:38681129 | PMC:PMC11045489 | DOI:10.3748/wjg.v30.i14.1990 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 29, 2024 Category: Gastroenterology Authors: Hong-Yi Zhu Jie Wu Yuan-Miao Zhang Fang-Lan Li Jin Yang Bin Qin Jiong Jiang Ning Zhu Meng-Yao Chen Bai-Cang Zou Source Type: research
