Integrated Bioinformatics Analysis of mRNAs and miRNAs Identified Potential Biomarkers of Oral Squamous Cell Carcinoma.
Conclusion: The roles of DEMs such as hsa-mir-5580-3p in OSCC through interactions with DEGs CD44, ACLY, ACTR3, STAT1, LAMC2 and YWHAZ may offer a suitable candidate biomarker pattern for diagnosis, prognosis and treatment processes in OSCC. PMID: 32597160 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - July 2, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Prevalence of JC and BK viruses in Patients with Colorectal Cancer: A Systematic Review and Meta- Analysis.
CONCLUSION: The prevalence of JCV in colorectal patients was substantially variable by different methods and targets. The significant association between JCV and CRC that was observed in the present study is not indicative of causation and should be studied more in large-scale prospective designs. PMID: 32592342 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Association of TP53 Codon 72 Arg > Pro Polymorphism with Breast and Lung Cancer Risk in the South Asian Population: A Meta-Analysis.
CONCLUSIONS: Our results indicate that TP53 Arg72Pro polymorphism is a risk factor for the development of breast cancer and lung cancer in the South Asian population. PMID: 32592343 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Do Subjective Norms Predict the Screening of Cancer Patients' First-Degree Relatives? A Systematic Review and Meta-Analysis.
Authors: Fattahi Ardakani M, Salehi-Abargouei A, Sotoudeh A, Esmaeildokht S, Bahrevar V Abstract BACKGROUND: Early detection and preventive measures can reduce the risk of cancer among first degree relatives (FDRs) of cancer patients.Several studies investigated the effect of subjective norm in relation to FDRs' tendency to conduct preventive behaviors. Therefore, the purpose of this study was to systematically evaluate the effect of subjective norms on cancer patients' FDRs as well as their willingness for screening. METHODS: PubMed and Scopus were studied to investigate the effect of subjective norms on preve...
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Dispersive Micro-Solid Phase Extraction for Sensitive Determination of Methotrexate from Human Saliva Followed by Spectrophotometric Method.
Authors: Jahed FS, Hamidi S, Galehassadi M Abstract For biological assessing of hospital personnel occupationally exposed to antineoplastic drugs, highly sensitive and accurate methods are required. Methotrexate (MTX) is an anticancer agent that is widely used in a variety of human cancers. For the first time, dispersive-micro solid phase extraction (D-µ-SPE) has been applied for determination of low levels of MTX in saliva samples. The method is based on rapid extraction of MTX using graphene oxide adsorbent. The sample preparation time is decreased by the fact that the adsorbent dispersed in the sample solu...
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Analyzing Survival Rate of Leukemia Patients Applying Long Term Exponential Model.
CONCLUSION: According to high percentage of censoring, using long-term model had better fit. PMID: 32592346 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

BCR-ABL Gene Transcript Types of Patients with Chronic Myelogenous Leukemia in Yogyakarta, Indonesia.
CONCLUSION: Ninety nine percent (99%) of CML patients in Yogyakarta, Indonesia are BCR-ABL positive, with 74.3% have b3a2 transcript, 22.4% have b2a2 trascript, 1.1% have co-expression of b3a2 and b2a2 transcript, and the rest (2.2%) have uncommon bands that still need to be confirmed. PMID: 32592347 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

A Study of Ser217Leu and Ala541Thr Polymorphism in the Men Afflicted with Prostate Cancer and in the Men being Suspicious of Prostate Cancer.
CONCLUSION: Results of this research showed that, in the individuals with the prostate cancer, there is a relationship between Ser217Leu and Ala541Thr polymorphism of ELAC2 gene and/with prostate cancer, and the suspicious individuals gotten involved in the mutation must take action to prevent this cancer.. PMID: 32592348 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

The Case to Case Comparison of Hormone Receptors and HER2 Status between Primary Breast Cancer and Synchronous Axillary Lymph Node Metastasis.
CONCLUSION: ER, PR and HER 2 biomarkers showed significant concordance between primary tumor and synchronous axillary lymph node metastasis. Hence, if we cannot assess the ER, PR and HER2 status in primary tumor, then synchronous axillary lymph node metastasis can be studied instead. However, the repeat of biomarker testing in node-positive breast cancer patients may be beneficial for tailored adjuvant therapy, especially for patients with negative hormone receptor and/or HER2 profile on primary tumor. PMID: 32592349 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Adherence to ASCO for Prophylaxis of Acute Chemotherapy- Induced Nausea and Vomiting in Iran.
CONCLUSION: Although our hospital is a referral and university-affiliated center, adherence to the ASCO guideline recommendations for prophylaxis of CINV was poor. PMID: 32592350 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Assessing CD 10 Expression Level and Its Prognostic Impact in Egyptian Patients with Urothelial Carcinoma.
In this study, 106 formalin fixed paraffin-embedded (FFPE) tissue of UCB, obtained through radical cystectomy specimen, and 10 matched normal tissue samples were included.CD10 expression was evaluated by immunohistochemistry and real time PCR techniques. RESULTS: CD10 expression in tumor cells and associated stromal fibroblasts was significantly associated with high tumor grade and advanced stage. Significant correlation was found between CD10 tumor expression and lymphovascular invasion (LVI) (P
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Associations of Single Nucleotide Polymorphism in miR-146a Gene with Susceptibility to Breast Cancer in the Iranian Female.
CONCLUSION: Overall, our results indicated no correlation between miR-146a G/C (rs2910164) polymorphism and genetic susceptibility to breast cancer in Iranian female populations. However, these findings need to be further confirmed by analyses of a larger number of cases. PMID: 32592352 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Natural Killer Cells Expanded and Preactivated Exhibit Enhanced Antitumor Activity against Different Tumor Cells in Vitro.
Authors: Biswas BK, Guru SA, Sumi MP, Jamatia E, Gupta RK, Lali P, Konar BC, Saxena A, Mir R Abstract One of the emerging treatment strategies for cancer particularly for haematological malignancies is natural killer (NK) cell therapy. However, the availability of a best approach to maximize NK cell anticancer potential is still awaited. It is well established that cytokine-induced memory-like NK cells have the potential to differentiate after a short period of preactivation with interleukins-IL-12, IL-15, and IL-18 and exhibit increased responses to cytokine or activating receptor restimulation for weeks to months...
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

The Expression of p53, CD44, Ki-67, and HER-2/neu Markers in Gastric Cancer and Its Association with Histopathological Indicators: A Retrospective Study.
CONCLUSION: This study illustrated that p53 and CD44 markers did not have any diagnostic value in predicting the biological behavior of gastric cancer. In fact, incidence of p53 gene was associated with the lower rate of survival, and the expression of HER-2/neu was associated with higher probability of developing the intestinal type of stomach adenocarcinoma and ulcerative macroscopic view. PMID: 32592354 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

The Ominous beginning" Perceptions of Smokeless Tobacco Initiation among the Paniya Tribes of Wayanad: A qualitative Study.
CONCLUSION: Targeted strategies for effective tobacco control can be developed through an understanding of the socio-cultural factors leading to initiation of smokeless tobacco use among disadvantaged communities. PMID: 32592355 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Associations of the -238(G/A) and -308(G/A) TNF- α Promoter Polymorphisms and TNF-α Serum Levels with the Susceptibility to Gastric Precancerous Lesions and Gastric Cancer Related to Helicobacter pylori Infection in a Moroccan Population.
CONCLUSION: The TNF-α -308 A allele has a promotive effect for GC progression, whereas the TNF-α -238 A allele has a protective function against GC progression. High levels of TNF-α seemed to be associated with the aggressiveness of gastric lesions. TNF-α gene polymorphisms and TNF-α serum levels might be helpful to select those patients who are at high risk for GC. PMID: 32592356 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Sentinel Node Biopsy in Early Breast Cancer Patients with Palpable Axillary Node.
In this study, the mean age of the patients was 49 years, 85% had invasive ductal carcinoma  in their pathology reports, 77% were ER/PR positive, 30% HER2 positive and 9.8% triple negative and 69% had KI6714% (p
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Glutathione S-transferase Polymorphisms in Head and Neck Squamous Cell Carcinoma Treated with Chemotherapy and/or Radiotherapy.
CONCLUSION: The GST polymorphisms combination showed an increased risk for carcinogenesis, and studies with larger casuistry can contribute to the clarification of the role in individual patient differences for the response to chemotherapy and/or radiotherapy and identify biomarkers of susceptibility. PMID: 32592358 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Gastric Cancer in Aktobe Region of Western Kazakhstan from 2009 to 2018: Incidence Rates, Trends, and Five-Year Survival.
Authors: Balmagambetova SK, Bekmukhambetov YZ, Tulyaeva AB, Iztleuov YM, Smagulova GA, Koyshybaev AK, Urazayev ON, Djussembekov ST, Begunov VV, Kokhreidze I Abstract OBJECTIVE: to assess the current state of gastric cancer (GC) incidence and its five-year survival across Aktobe region of western Kazakhstan from 2009 to 2018 by presenting key indicators and analyzing the most significant features. METHODS: Rough incidence rates (per 100,000) and average annual percent changes (aAPCs) were estimated for each age group at diagnosis with respect to gender, ethnicity, residence, the disease stages, tumor subsite, an...
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Conflict of Interest: Are Iranian Breast Cancer Specialists Prone to it?
CONCLUSION: This study indicated that physicians in the field of breast cancer were at the risk of COI. Even within the medical field, there is not sufficient trust in the proper functioning of doctors in dealing with COI situations.. PMID: 32592360 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Dosimetric Validation of Digital Megavolt Imager for Flattening Filter Free Beams in the Pre-Treatment Quality Assurance of Stereotactic Body Radiation Therapy for Liver Metastases.
Authors: Subramani V, Rathakrishnan M, N AN, S SC, Venkatraman M Abstract AIM: The aim is to evaluate the use of digital megavolt imager (DMI) aS1200 in portal dosimetry with flattening filter free (FFF) beams. MATERIALS AND METHODS: Dosimetric properties of DMI is characterized at 6MV FFF beams for signal saturation, dose linearity, dependency on dose-rate and source-detector distance (SDD), signal lag (ghosting), and back scatter.  Portal dosimetry is done for twenty volumetric modulated arc therapy (VMAT) based stereotactic body radiotherapy (SBRT) plans for the treatment of liver metastases and the res...
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Health Promoting Lifestyle and its Relationship with Self-Efficacy in Iranian Mastectomized Women.
Authors: Hamed Bieyabanie M, Mirghafourvand M Abstract INTRODUCTION: Lifestyle modification has an important role in long-term health of breast cancer patients. As a result, this study aimed to identify the health-promoting lifestyle and its subdomains in mastectomized women and its relationship with self-efficacy. MATERIALS AND METHODS: This cross-sectional study investigated 100 mastectomized women in Tabriz-Iran, 2018. The participants were selected using the convenience sampling method. Data was collected using a sociodemographic questionnaire, the Health Promoting Lifestyle Profile II (HPLP-II), and the Ge...
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Diagnostic delay for head and neck cancer in South India: A Mixed-methods Study.
CONCLUSIONS: The diagnostic delay was considerable. Measures to enhance symptom appraisal by improving health literacy, opportunistic screening, and strengthening the referral system would decrease diagnostic delay. PMID: 32592363 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Characteristics and Impact of HPV-Associated p16 Expression on Head and Neck Squamous Cell Carcinoma in Thai Patients.
CONCLUSIONS: In comparison to the results from the Western countries, the prevalence of HPV-related HNSCC in Thai patients was less, and differences in some characteristics were observed. Nevertheless, improvement in OS, DFS and LRFS were observed in p16-positive patients. Our analyses suggested that p16 status is also a strong prognostic marker for HNSCC patients in Thailand. PMID: 32592364 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Clinical Potentials of miR-576-3p, miR-613, NDRG2 and YKL40 in Colorectal Cancer Patients.
Authors: Eldaly MN, Metwally FM, Shousha WG, El-Saiid AS, Ramadan SS Abstract INTRODUCTION: Colorectal cancer (CRC) is the most common type of gastrointestinal tract cancers. This investigation aim was to assess the expression of miR-576-3p and miR-613 in CRC patients in addition to NDRG2 and YKL40 serum levels determination to decide their diagnostic and prognostic significance. METHODS: Sixty early diagnosed CRC patients prior to any treatment in addition to twelve healthy subjects were enrolled in this study. Blood samples were taken from subjects and allowed for clotting and centrifugation, then the collect...
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Predictors of the Onset of Type 1 Diabetes Obtained from Real-World Data Analysis in Cancer Patients Treated with Immune Checkpoint Inhibitors.
This study used data extracted from the Japan Adverse Drug Event Report (JADER) database to assess risk factors associated with serious side effects of irAE, type 1 diabetes (T1DM). The analysis targets were nivolumab, atezolizumab, durvalumab, and pembrolizumab, and the study period was from July 2014 to June 2019. Analysis of Japanese population data confirmed that being women and having melanoma were risk factors for developing ICI-related T1DM. Analysis using this database in combination with information on ICI-related T1DM provides information and guidelines that will help in the safer treatment of ICI in the future. ...
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Intake of Common Alcoholic and Non-Alcoholic Beverages and Breast Cancer Risk among Japanese Women: Findings from the Japan Collaborative Cohort Study.
This study investigated the association between intake of common alcoholic and non-alcoholic beverages and breast cancer risk among Japanese women. This study included 33,396 Japanese women aged 40-79 years from 24 areas in Japan from the Collaborative Cohort study. During the follow-up period (≥20 years), 245 incidents or mortal breast cancers were documented. Multivariable logistic regression analysis was performed to assess the independent association between breast cancer risk and the intake of Japanese green tea, coffee, and alcohol. Japanese green tea was the most commonly consumed non-alcoholic beverage (81.6% of...
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Synergistic Effect of Benzethonium Chloride Combined with Endoxan against Hepatocellular Carcinoma in Rats through Targeting Apoptosis Signaling Pathway.
Authors: Abozaid OAR, Moawed FSM, Farrag MA, Kawara RSM Abstract Combination therapy has been the trendy of care, particularly in cancer remedy, since it is a rational approach to increase response and tolerability and to diminish resistance. Hence, there is a growing interest in combining anticancer drugs to maximizing efficacy with minimum systemic toxicity through the delivery of lower drug doses. Therefore, in the present study, the value of combination between benzethonium chloride (benzo) and endoxan (endo) as anti-tumor drug sensitization of hepatocellular carcinoma HCC treatment were detected both in vitro ...
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Neoadjuvant FOLFIRINOX followed by Chemoradiotherapy for Middle and Lower Rectal Cancer.
CONCLUSION: Neoadjuvant FOLFIRINOX followed by CRT for middle and lower rectal cancer is feasible, tolerable with satisfactory sphincter preservation rate. . PMID: 32592369 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Driving to Childhood Cancer Hub Hospitals: A Study on Hospital Accessibility in Japan.
CONCLUSIONS: Although feasibility is ultimately dependent on each patient's condition and situation, child cancer patients on average can likely complete hospital visits from home and return within a single day. However, this is likely not the case for children who live at considerable distances from hub hospitals. We found regional differences in travel times and distances, depending on whether a given block contained multiple hub hospitals. PMID: 32592370 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Effect of Hip Prosthesis on Photon Beam Characteristics in Radiological Physics.
CONCLUSION: The perturbation index varied from 0.05 to 0.22 for the measured energies and gave an idea to the planner to assess the behavior of the prosthesis. This range is applicable for both type of implants and for all clinical field-sizes. The attenuation caused by the prosthesis was significant and this effect should be considered in the treatment planning calculations. PMID: 32592371 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Microarray Analysis of Gene Expression Involved in Butyrate-Resistant Colorectal Carcinoma HCT116 Cells.
CONCLUSION: Our findings shed light on the transcriptomic profiles of chemoresistant CRC cells. This data should be useful for further study to provide guidelines for clinical prognosis to determine the guidelines for CRC treatment, especially in patients with chemoresistance and designing novel anti-neoplastic agents. PMID: 32592372 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

MiRNA-7 Replacement Effect on Proliferation and Tarceva-Sensitivity in U373-MG Cell Line.
Authors: Alamdari-Palangi V, Karami Z, Karami H, Baazm M Abstract BACKGROUND: Deregulation of the EGFR signaling pathway activity has been shown to can be effective in resistance to EGFR-TKIs, such as Tarceva (erlotinib), in glioblastoma cells. In addition, reports have shown that the reduction of miRNA-7 expression levels is associated with an increase in the expression of EGFR. Here, we evaluated the effect of miRNA-7 on EGFR expression and sensitivity of the U373-MG glioblastoma to erlotinib. METHODS: The effect of miRNA-7 on EGFR expression was examined using RT-qPCR and western blotting. Trypan blue and MT...
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Prophylactic Chemotherapy with Methotrexate Leucovorin in High-Risk Hydatidiform Mole.
CONCLUSION: This study concludes that prophylactic chemotherapy with MTX and leucovorin may be capable of reducing GTN, which supports the prescription of MTX in high-risk mole, especially in countries with limited resources. The toxicity of methotrexate can be reduced with the addition of leucovorin.. PMID: 32592374 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Age-Period-Cohort Analysis of the Sex Differences in Cancer Mortality Rates in Japan from 1995 to 2015.
CONCLUSION: The sex differences in cancer mortality rates were decreasing in the more recent born generations in Japan. If this trend continues, there will be a minimal difference in the morality rates in the following generations.. PMID: 32592375 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Methylene Blue Absorption in Sentinel Lymph Node Biopsy for Early Breast Cancer after Neoadjuvant Chemotherapy.
In this study, the researchers used methylene blue only and wished to evaluate the methylene blue absorption of the SLNB procedure on early-stage breast-cancer patients after neoadjuvant chemotherapy (NAC). MATERIALS AND METHODS: The method used was the historical cohort study conducted from 2016-2019 in Indonesia. Samples were collected from 117 patients of stage I and II breast cancer with clinically negative axillary lymph nodes, who were then grouped into post-NAC and no-NAC (control group), in which SLNB procedures were conducted on the two groups by using single-method methylene blue. The results of methylene blu...
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Hsp90 Inhibitor; NVP-AUY922 in Combination with Doxorubicin Induces Apoptosis and Downregulates VEGF in MCF-7 Breast Cancer Cell Line.
Authors: Mohammadian M, Feizollahzadeh S, Mahmoudi R, Toofani Milani A, Rezapour-Firouzi S, Karimi Douna B Abstract OBJECTIVE: Breast cancer is one of the most prevalent malignancies and leading causes of females' mortality worldwide. Because of resistance to various treatment options, new treatments based on molecular targeting has introduced as noticeable strategies in cancer treatment. In this regard, heat shock protein 90 (Hsp90) inhibitors are proposed as effective anticancer drugs. The goal of the study was to utilize a combination of the doxorubicin (DOX) and NVP-AUY 922 on the MCF-7 breast cancer model to i...
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Mortality from Selected Cancers among Brazilian Mechanics.
CONCLUSION: Results of our study suggest a positive association between mechanic occupation and some specific cancers.. PMID: 32592378 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Risk Scoring System based on lncRNA Expression for Predicting Survival in Hepatocellular Carcinoma with Cirrhosis.
CONCLUSION: Risk scoring systems based on lncRNAs can effectively predict OS of HCC patients with cirrhosis. The system should be further developed and validated in larger, preferably multi-site patient populations.. PMID: 32592379 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

The Prognosis of Hepatocellular Carcinoma Treated with Sorafenib in Combination with TACE.
CONCLUSION: With an array of therapeutic options currently available, it is important to determine the efficacy of different multimodal strategies, such as sorafenib combined TACE, for patients with unresectable HCC. PMID: 32592380 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Randomized Pilot Study of 20 Gy in 5 Fractions versus 27 Gy in 3 Fractions Radiotherapy for Treating Painful Bone Metastases: A Single Institution Experience.
CONCLUSION: SBRT and standard fractionation radiation therapy had equal effectiveness for pain relief, when the assessment was done after three months of radiation therapy. Interestingly, SBRT had a better immediate pain relief. . PMID: 32592381 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Effect of a Pedometer-based Exercise Program on Cancer Related Fatigue and Quality of Life amongst Patients with Breast Cancer Receiving Chemotherapy.
CONCLUSION: A 7-week pedometer-based exercise program improved functional capacity, quality of life and percentage of skeletal mass and also shows to have prevented deterioration in fatigue levels in patients with breast cancer receiving chemotherapy. PMID: 32592382 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Investigation of the Effect of Zebularine in Comparison to and in Combination with Trichostatin A on p21Cip1/Waf1/ Sdi1, p27Kip1, p57Kip2, DNA Methyltransferases and Histone Deacetylases in Colon Cancer LS 180 Cell Line.
CONCLUSION: The zebularine and TSA can reactivate the CIP/KIP family through inhibition of DNMTs and HDACs genes activity.. PMID: 32592383 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Serum Folate Levels and Lung Cancer Risk: A Meta- Epidemiological Study of Population-based Case-Control Studies.
CONCLUSION: Higher foliate levels can decrease lung cancer risk in men and former smokers. Especially, the protective effect was highest in former smokers compared in non-smokers and current smokers. Based on these facts, folate fortification programs to reduce lung cancer risk would be focused on former smokers in men. And some epidemiological studies are needed to provide a hypothesis to explain the sex differences in the association between folate and lung cancer risk. PMID: 32592384 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Factors Associated with Time Intervals for Diagnosis of Colorectal Cancer: A Hospital Based Study in Khon Kaen, Thailand.
CONCLUSIONS: The results showed the occupation, first health care visit, distance and cost were factors associated with TID. Improving the facilities at the secondary healthcare units for diagnosing CRC would be likely to help to reduce the  wasted time in the  healthcare system. PMID: 32592385 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Hemato- Oncology Care in COVID-19 Pandemic: Crisis within a Crisis.
Authors: Seth T, Shankar A, Roy S, Saini D PMID: 32458618 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - May 28, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Coffee Consumption and Colon Cancer Risk: A Meta- Epidemiological Study of Asian Cohort Studies.
CONCLUSIONS: The results suggest that coffee consumption is not associated with the risk of colon cancer in Asian men and women. The findings of this study are consistent with the results of two systematic reviews conducted under the same hypothesis and selection criteria. Additional epidemiological studies are needed for the inflection of colon cancer risk as the dose of coffee increases and the difference in the protective effect by sex. PMID: 32458619 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - May 28, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Alternation of β-catenin and CD44s Immunoexpression in Different Histopathological Grades of Oral Squamous Cell Carcinoma.
CONCLUSION: Expression of β-catenin and CD44s alter in different histopathological grades of OSCC. It seems that more rate of aberrant cytoplasmic and/nuclear expression and less membranous expression of β-catenin can lead to significantly lower degree of cell differentiation in OSCC. . PMID: 32458620 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - May 28, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Indocyanine Green Fluorescence Versus Blue Dye or Radioisotope Regarding Detection Rate of Sentinel Lymph Node Biopsy and Nodes Removed in Breast Cancer: A Systematic Review and Meta-Analysis.
CONCLUSION: ICG-SLNB could be an additional or an alternative method for axillary node mapping in breast cancer.. PMID: 32458621 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - May 28, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Association of IL-12B rs3212227 and IL-6 rs1800795 Polymorphisms with Susceptibility to Cervical Cancer: A Systematic Review and Meta-Analysis.
CONCLUSIONS: Our pooled data revealed that the IL-12B rs3212227 and IL-6 rs1800795 polymorphisms may be used to identify individuals at high risk of cervical cancer in Asian women.. PMID: 32458622 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - May 28, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research