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Cancer Screening Awareness and Practice in a Middle Income Country; A Systematic Review from Ira
Conclusion: Low awareness and suboptimal use of screening tests in Iran calls for effective programs to enhance intention and compliance to screening, improving the patient-physician communication, identifying barriers for screening and providing tailored public awareness and screening programs. PMID: 29281865 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Comparative Diagnostic Performance of Ultrasonography and 99mTc-Sestamibi Scintigraphy for Parathyroid Adenoma in Primary Hyperparathyroidism; Systematic Review and Meta- Analysis
Authors: Nafisi Moghadam R, Amlelshahbaz AP, Namiranian N, Sobhan-Ardekani M, Emami-Meybodi M, Dehghan A, Rahmanian M, Razavi-Ratki SK Abstract Objective: Ultrasonography (US) and parathyroid scintigraphy (PS) with 99mTc-MIBI are common methods for preoperative localization of parathyroid adenomas but there discrepancies exist with regard to diagnostic accuracy. The aim of the study was to compare PS and US for localization of parathyroid adenoma with a systematic review and meta-analysis of the literature. Methods: Pub Med, Scopus (EMbase), Web of Science and the reference lists of all included studies were search...
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Breast Cancer Risk From Modifiable and Non-Modifiable Risk Factors among Women in Southeast Asia: A Meta-Analysis
Conclusion: This analysis confirmed associations between both modifiable risk factors (parity, body mass index and use of oral contraceptives) and non-modifiable risk factors (family history of breast cancer, age and menopausal status) with breast cancer. PMID: 29281867 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Positive Effects of Cognitive Behavioral Therapy on Depression, Anxiety and Stress of Family Caregivers of Patients with Prostate Cancer: A Randomized Clinical Trial
Conclusion: Because of the positive impact of this intervention, its implementation in clinical care by nurses is recommended. PMID: 29281868 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Pattern of Pediatric Oncology Cases in the Western Region of Nepal
The objective of this study was to establish the pattern of childhood cancers in the Western region of Nepal. We reviewed cases receiving external radiotherapy with both palliative and curative intent between 28th September 2010 and 30th September 2015 at the Department of Radiotherapy and Oncology, Manipal Teaching Hospital affiliated with Manipal College of Medical Sciences, Pokhara, Nepal. Of the total of 1217 cases, 2.71% involved children. The gender distribution showed a male preponderance (M:F= 1.35:1). The patients’ mean age was 11.4 years (range 2 - 14 years). Considering the caste, Brahmins and Gurungs cons...
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Knowledge, Attitudes, Preventive Practices and Screening Intention about Colorectal Cancer and the Related Factors among Residents in Guangzhou, China
Conclusion: These results suggested that the priority may be laid on improving the conversion from knowledge to practice to implement screening program in Guangzhou, while efforts should also be made to improve public awareness about CRC. PMID: 29281875 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Concentration- Dependent Effects of Curcumin on 5-Fluorouracil Efficacy in Bladder Cancer Cells
Conclusion: Our findings suggest a crucial role of Cur concentration in regulating chemotherapeutic agent-induced cytotoxicity. Further investigations are needed to understand the precise mechanisms of action of Cur and determine appropriate doses with combination therapy for clinical application against human cancers. PMID: 29281876 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Cellular and Molecular Changes in MNU-Induced Breast Tumours Injected with PF4 or bFGF
Conclusion: ER and PR receptor expression shows consistent responses when tumour angiogenesis is manipulated either positively or negatively. Our study adds to current understanding that not only do we need to target hormonal receptors, as presently practiced, but we also need to target endothelial receptors to successfully treat breast cancer. PMID: 29281877 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Risk Factors for Invasive Fungal Infection among Thai Oncologic Patients with Febrile Neutropenia and Cutaneous Presentation: A 5-Year Retrospective Study in Southern Thailand
Conclusions: There are a variety of cutaneous manifestations in FNP, of which the most common were cutaneous nodular skin lesions in the lower extremities. The most frequent infection was fungal in patients under 40 who had developed skin lesions after FNP. PMID: 29286213 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Lack of Associations between TLR9 and MYD88 Gene Polymorphisms and Risk of Chronic Lymphocytic Leukemia
Conclusion: Our preliminary data suggest that polymorphisms in the TLR9 and MYD88 genes may not contribute to CLL susceptibility. To the best of our knowledge, this study is the first dealing with TLR9 and MYD88 gene polymorphisms in CLL patients. Further studies with larger sample size should be conducted to validate these results in the Egyptian population. PMID: 29286214 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Inter- and Intra-Observer Variability in Diagnosis of Oral Dysplasia
Conclusion: Our study provides evidence that the existing systems for grading dysplasia are not competent to rule out subjectivity. There is a need for a classification system that can overcome this drawback. PMID: 29286215 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Phosphorylated Akt Protein at Ser473 Enables HeLa Cells to Tolerate Nutrient-Deprived Conditions
Conclusion: Results of the present study provide evidence that Akt activation may be implicated in the tolerance of HeLa cells for nutrient starvation and may help to suggest new therapeutic strategies designed to prevent austerity of cervical cancer cells through inhibition of Akt activation. PMID: 29286216 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Knowledge and Perceptions about Cancer Treatment-associated Infertility among Young Patients at a Tertiary Care Hospital in Pakistan
In this study we assessed knowledge and perceptions among young cancer patients regarding the topic of cancer and infertility related to different treatment options. Material and Methods: This cross-sectional study was conducted on young cancer patients in the Clinical Oncology Department, JPMC, Karachi, from January to August 2013. Patients were requested to fill in questionnaires. Comparisons between gender and age groups were performed using the Student’s t test and Pearson’s Chi-squared. Significance was concluded with a two tailed p-value less than 0.05. Results: The survey included 368 cancer patients, 19...
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Seroepidemiological Study of Hepatitis B, C and HIV among Blood Donors in Kerman
Conclusion: Blood-borne viral infections in people with low education levels were more common. The prevalence in Kerman province was low as compared to previous studies carried out in other regions of Iran. Application of standard operating procedures, with updated equipment, as well as planning for the use of molecular methods are necessary for the Iranian Blood Transfusion Organization, to monitor blood-transmitted infections. PMID: 29286218 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Aloe-Emodin Influence on the Lysosomal Compartment of Hela Cells
Conclusion: The results indicate that aloeemodin can activate lysosomal pathway-dependent apoptosis in HeLa cells. PMID: 29286219 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

The Correlates of Kidney Dysfunction – Tumour Nephrectomy Database (CKD-TUNED) Study: Protocol for a Prospective Observational Study
Conclusion: It is anticipated that this study will have the potential to identify risk factors for adverse renal functional outcomes following tumour nephrectomy, which can be used in the development of predictive models with clinical utility, and in turn improve patient outcomes. PMID: 29286220 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Prognostic Significance of Indicators of Systemic Inflammatory Responses in Glioblastoma Patients
Conclusion: The present findings confirm that NLR based on peripheral blood counts prior to treatment can be used as a prognostic factor in patients with glioblastoma. Since tumour aggression increases and survival decreases as the NLR value rises, choice of treatment modality is facilitated for glioblastoma patients. PMID: 29286221 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

BRCA1 Promoter Methylation and Expression - Associations with ER+, PR+ and HER2+ Subtypes of Breast Carcinoma
Authors: Kumar M, Sahu RK, Goyal A, Sharma S, Kaur N, Mehrotra R, Singh UR, Hedau S Abstract Introduction: Considering the increasing trend in incidence rates, morbidity and mortality of breast cancer, there is an urgent need to identify and validate new biomarkers for early detection and better management. The purpose of the study was to investigate BRCA1 protein expression and promoter methylation of the BRCA1 gene and their association with molecular subtypes based on estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) positivity. Materials and Methods: A total ...
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Astrocyte Elevated Gene 1 (AEG-1): A Promising Candidate for Molecular Targeted Therapy in Oral Squamous Cell Carcinomas
Conclusion: The current results support some role of AEG-1 in genesis of oral squamous cell carcinomas. PMID: 29286223 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Utility of 5-Methylcytosine Immunohistochemical Staining to Assess Global DNA Methylation and Its Prognostic Impact in MDS Patients
Conclusion: Immunostaining with anti-5-MC antibody with BM Bx samples is a simple and cost effective technique to detect global methylation, a powerful tool to predict overall survival in patients with MDS. PMID: 29286224 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Comparison of Salivary Antioxidants in Children with Primary Tooth Abscesses before and after Treatment in Comparison with Healthy Subjects
Conclusion: Under the conditions of this study the total antioxidant capacity of saliva was not compromised in children with abscessed teeth. PMID: 29286225 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Almost Complete Lack of Human Cytomegalovirus and Human papillomaviruses Genome in Benign and Malignant Breast Lesions in Shiraz, Southwest of Iran
Conclusion: The results of this study indicated no relationship between HCMV or HPV infection with breast cancer development. Whether investigations in larger populations with longer follow-up might demonstrate any role remains unclear. PMID: 29286226 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Quality of Life Determinants in Breast Cancer Patients in Central Rural India
Conclusions: The present study demonstrated a moderate QOL in women with breast cancer in rural India. Young age, lack of education and being without a partner were negatively related to QOL, and employment as casual and industrial workers, high monthly family income and higher self-efficacy were positively associated with QOL. A comprehensive public health initiative is required, including social, financial and environmental support, that can provide better QOL for breast cancer survivors. PMID: 29286227 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Effects of Damnacanthal and Nordamnacanthal on Proliferation, Apoptosis, and Migration of Oral Squamous Cell Carcinoma Cells
The objectives of this study were to evaluate cytotoxicity, morphological changes, cell death mode (apoptosis/necrosis), and cell migration induced by DAM and NDAM on the most common type of oral cancer, oral squamous cell carcinoma (OSCC)cells. Anti-proliferative effects of these compounds against OSCC cell lines were determined by MTT assay. The mode of cell death was analysed by phase contrast and fluorescent microscopy as well as flow cytometry. In addition, cell migration was assessed. The results showed that DAM and NDAM exerted cytotoxicity against OSCC cells with IC50 values of 1.9 to>30 μg/ml after 72 h trea...
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Synergistic Effect of Forbesione From Garcinia hanburyi in Combination with 5-Fluorouracil on Cholangiocarcinoma
This study aimed to investigate the synergistic effects of forbesione combined with 5-fluorouracil (5-FU) in hamster cholangiocarcinoma (Ham-1) cells both in vitro and in vivo. The anti-tumor effects of 5-FU combined with forbesione in vitro were determined using the Sulforhodamine B (SRB) assay and the effects in vivo were assessed in transplanted Ham-1 allograph models. Using ethidium bromide/acridine orange (EB/AO) staining, the morphological changes of apoptotic cells was investigated. The expressions of apoptosis-related molecules after combined treatment with forbesione and 5-FU were determined using real-time RT-PCR...
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Low Body Mass Index Is an Independent Predictive Factor after Surgical Resection in Patients with Non-Small Cell Lung Cancer
Authors: Tomita M, Ayabe T, Nakamura K Abstract Background: The effect of body mass index (BMI) on postoperative survival in non-small cell lung cancer (NSCLC) has been controversial. We retrospectively analysed the effect of preoperative BMI on postoperative outcomes of NSCLC surgery. Methods: Consecutive 384 NSCLC patients were enrolled. Patients were subdivided into 3 groups: low BMI group (BMI24.0 kg/m2). The prognostic significance of BMI was examined retrospectively. Results: The 5-year survival of patients with low, normal and high BMI groups were 46.3%, 74.3% and 84.3%, respectively. The low BMI group had a...
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Protein-Protein Interaction Network Analysis for a Biomarker Panel Related to Human Esophageal Adenocarcinoma
Conclusion: The findings indicate nine crucial proteins could form a candidate biomarker panel for EAC. Furthermore, an important cluster with 27 proteins related to the disease was identified. Gene ontology analysis of this cluster showed main related terms to closely correspond with those for colorectal cancer. PMID: 29286604 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Treatment-Related Quality of Life in Nepalese Women with Breast Cancer
Conclusions: As Nepalese women reported decreased quality of life, nurses should provide preventive and supportive services to improve the quality of life of their patients during chemotherapy. PMID: 29286605 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Human Papilloma Virus Genotype Distribution in Cervical lesions in Zanjan, Iran
Conclusion: While HPV infection is the major etiological factor for cervical cancer, presence was relatively low in our survey. In the positive cases, however, HPV18 was the most common in line with many other populations. The fact that types vary among different populations must clearly be taken into account in design of vaccines for our country. PMID: 29286606 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Limited Understanding of Pap Smear Testing among Women, a Barrier to Cervical Cancer Screening in the United Arab Emirates
Authors: AL-Hammadi FA, Al-Tahri F, Al-Ali A, Nair SC, Abdulrahman M Abstract Global data indicate that cervical cancer is the fourth most common cancer among women worldwide. Important factors that affect interventions for early diagnosis of cervical cancer include social beliefs and values and poor knowledge. These may contribute to women’s participation in screening for cervical cancer and have a significant impact on decisions to take preventive action. The present study was conducted with 599 women in the UAE between September 2016 and March 2017. A cross-sectional survey was conducted to determine knowl...
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Cox Regression and Parametric Models: Comparison of How They Determine Factors Influencing Survival of Patients with Non-Small Cell Lung Carcinoma
Conclusion: The most efficient model was a log-normal model. Implementation of optimal therapies at early stages can improve the survival of patients. PMID: 29286608 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Lung Lesion Detection in CT Scan Images Using the Fuzzy Local Information Cluster Means (FLICM) Automatic Segmentation Algorithm and Back Propagation Network Classification
Authors: Lavanya M, Kannan PM Abstract Lung cancer is a frequently lethal disease often causing death of human beings at an early age because of uncontrolled cell growth in the lung tissues. The diagnostic methods available are less than effective for detection of cancer. Therefore an automatic lesion segmentation method with computed tomography (CT) scans has been developed. However it is very difficult to perform automatic identification and segmentation of lung tumours with good accuracy because of the existence of variation in lesions. This paper describes the application of a robust lesion detection and segmen...
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Cancer Mortality, Early Detection and Treatment among Adult New Zealanders: Changes in Perceptions between 2001 and 2014/5
Conclusion: Internationally, there is little information available about changes in cancer perceptions over time, these findings suggest some changes in perceptions of treatment and awareness of types of cancer with the highest mortality in NZ, which should support timely engagement with early detection and treatment services. PMID: 29286610 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Descriptive Epidemiology of Cancers in Togo from 2009 to 2016
Conclusion: Cancers are frequent in Togo, those of the prostate, breast and cervix being most important with a worse prognosis. Emphasis should be placed on early detection and diagnosis. PMID: 29286611 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Unexpected Lower Expression of Oncoprotein Gankyrin in Drug Resistant ABCG2 Overexpressing Breast Cancer Cell Lines
Conclusion: These findings showed that there may be a relation between down-regulation of Gankyrin and overexpression of ABCG2 but without any clear relationship with MDR1 expression in breast cancer cell lines. PMID: 29286612 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Vitamin D Deficiency Associated with Differentiated Thyroid Carcinoma: A Case- Control Study
Conclusion: A significant association was noted between vitamin D deficiency and differentiated thyroid cancer. Further studies with a prospective design are necessary to further define the roles of this factor. PMID: 29286613 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

TP53 Gene Pro72Arg (rs1042522) Single Nucleotide Polymorphism as Not a Risk Factor for Colorectal Cancer in the Iranian Azari Population
Conclusions: Pro72Arg SNP of TP53 gene may not be involved in the disease pathogenesis in Iranian Azari patients with colorectal cancer. PMID: 29286614 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

EpCAM-based Flow Cytometric Detection of Circulating Tumor Cells in Gallbladder Carcinoma Cases
Conclusion: Detection and quantification of CTCs may serve as a non-invasive biomarker for GBC diagnosis in correlation with radiological studies. PMID: 29286615 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Dosimetric Validation of Volumetric Modulated Arc Therapy with Three 6MV Beam-Matched Linear Accelerators
Conclusion: Our study evaluation of beam matching with treatment planning modeling showed good agreement fior 6 MV beams across all three linear accelerators used in our clinical environment. PMID: 29286616 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Genistein and Trichostatin A Induction of Estrogen Receptor Alpha Gene Expression, Apoptosis and Cell Growth Inhibition in Hepatocellular Carcinoma HepG 2 Cells
Conclusion: GE and TSA can significantly inhibit the growth of HCC cells and play a significant role in apoptosis and reactivation of ERα gene. PMID: 29286617 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Cancer Detection in Microarray Data Using a Modified Cat Swarm Optimization Clustering Approach
Conclusion: The results showed MCSO-HS to outperform HS and CSO with both benchmark datasets. To validate the clustering results, this work was tested with internal and external cluster validation indices. Also this work points to biological validation of clusters with gene ontology in terms of function, process and component. PMID: 29286618 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Comparison of Diagnostic Yield of a FISH Panel Against Conventional Cytogenetic Studies for Hematological Malignancies: A South Indian Referral Laboratory Analysis Of 201 Cases
Conclusions: In conclusion, FISH was found to be advantageous in only a subset of HMs and cannot completely replace CCS. Utilization of the two modalities in conjunction or independently should depend on the indicated HM for an optimal approach to detecting chromosomal aberrations. PMID: 29286619 [PubMed - as supplied by publisher] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - December 31, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

UICC-ARO Symposium at the UICC 2016 World Cancer Congress How Can We Mobilize Action to Realize UHC in Asia?
Authors: Akaza H, Kawahara N, Fukuda T, Horie S, Thabrany H, Nozaki S Abstract The 2016 World Cancer Congress, organised by UICC, was held in Paris in November 2016, under the theme “Mobilizing action – Inspiring Change.” As part of Track 4 presentations on the theme of “Strengthening cancer control: optimizing outcomes of health systems,” UICC-Asian Regional Office (UICC-ARO) held a symposium to discuss the issue of mobilizing action to realize UHC in Asia. Introducing the symposium, Hideyuki Akaza noted that universal health coverage (UHC) is included in the Sustainable Development G...
Source: Asian Pacific Journal of Cancer Prevention - November 29, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Clinicopathological Significance of MTA 1 Expression in Patients with Non-Small Cell Lung Cancer: A Meta-Analysis
Authors: Zhu W, Li G, Guo H, Chen H, Xu X, Long J, Zeng C, Wang X Abstract Background: Metastasis associated gene 1(MTA1) is one of the most deregulated molecules in human cancer and leads to cancer progression and metastasis. We performed a meta-analysis to determine the correlations between MTA1 expression and the clinicopathological characteristics of non-small cell lung cancer (NSCLC). Methods: We searched PubMed, Springer, Science Direct, Google Scholar and China National Knowledge Infrastructure (CNKI) for relevant articles. For statistical analyses, we used R3.1.1 software. The fixed or random effects model ...
Source: Asian Pacific Journal of Cancer Prevention - November 29, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Dual Function of Gold Nanoparticles in Synergism with Mitoxantrone and Microwave Hyperthermia Against Melanoma Cells
This study was performed to evaluate any synergetic effects of mitoxantrone (MX) and gold nanoparticles (GNPs) as dual therapeutic approach, along with microwave (MW) hyperthermia for melanoma cancer. Methods: Various tests were performed on the DFW melanoma cell line in the presence of MX and different concentrations of GNPs, with and without MW irradiation. MTT [3-(4,5-dimethylthiazol–2-yl)-2,5-iphenyltetrazolium bromide] assays were conducted to evaluate the effectiveness of the used therapeutic methods in terms of cell survival. Relative lethal synergism (RLS) was calculated as the ratio of cell death following h...
Source: Asian Pacific Journal of Cancer Prevention - November 29, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Anthocyanins from the Fruit of Vitis Coignetiae Pulliat Inhibit TNF-Augmented Cancer Proliferation, Migration, and Invasion in A549 Cells
Conclusion: This study demonstrates that the anthocyanins isolated from fruits of Vitis coignetiae Pulliat inhibit cancer proliferation, cancer migration, and invasion that is involve in cancer-metastasis. This study provides evidence that AIMs might have anti-cancer effects on human lung cancer. PMID: 29172259 [PubMed] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - November 29, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

The Lys469glu/K469E Polymorphism of the Inflammatory Gene Intercellular Adhesion Molecule-1 Lacks any Apparent Role in the Polycystic Ovary Syndrome in Kashmiri Women: A Case Control Study
Conclusion: In conclusion, there was no apparent significant influence of the K469E polymorphism on risk of PCOS, or any clinical or laboratory parameters. PMID: 29172260 [PubMed] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - November 29, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Knowledge of Evidence-Based Cancer Risk Factors Remains Low Among New Zealand Adults: Findings from Two Cross-Sectional Studies, 2001 and 2015
Conclusions: Effective communication of risk information for specific cancers remains a challenge for cancer control. Although some positive changes in awareness over the 14 year period were observed, there remains substantial room for progressing awareness of evidence-based risk factors. PMID: 29172261 [PubMed] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - November 29, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Modulatory Effects of Chemoradiation on Angiogenic Factors and Laminin in Cervical Cancer: Link with Treatment Response
Authors: Sharma M, Khan R, Aggarwal M, Sharma A Abstract Objective: Carcinoma of the uterine cervix is either the first or second most common malignancy in Indian women, depending on the registry. Tumor growth and metastasis primarily are determined by angiogenesis and parameters of the molecular environment including extracellular matrix elements, growth factors and cytokines. Effects of chemo-irradiation on biomarkers like vascular endothelial growth factor (VEGF), angiopoietin-2 (Ang-2) and laminin in patients with carcinoma cervix therefore need to be explored. Methods: Circulatory and mRNA levels of VEGF, Ang-...
Source: Asian Pacific Journal of Cancer Prevention - November 29, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Predicting Intention Perform Breast Self-Examination: Application of the Theory of Reasoned Action
Conclusion: TRA could be a suitable model to predict BSE intentions . Participants who believed that doing BSE regularly is beneficial for early diagnosis of breast cancer and also believed that their significant referents think that doing BSE would significantly detect breast cancer earlier, were more likely to intend to perform BSE regularly. Therefore, the research findings supported the conclusion that promoting the importance of BSE at the community/social level would enhance individuals to perform BSE routinely. PMID: 29172263 [PubMed] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - November 29, 2017 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research