Association between IL-18 -607 C/A Polymorphism and the Risk of Prostate Cancer: A Meta-Analysis of Case-Control Studies.
CONCLUSION: This meta-analysis has shown that IL-18-607 C/A polymorphism contributes to a decreased risk of prostate cancer risk in the Asian population but an increasedrisk in the Caucasian population. PMID: 31244277 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Comparison of Qualitative (Time Intensity Curve Analysis), Semi-Quantitative, and Quantitative Multi-Phase 3T DCEMRI Parameters as Predictors of Malignancy in Adnexal.
CONCLUSION: We concluded that a Type I TICconfirms a benign lesion, and a type III TIC confirms the malignancy and further evaluation is not recommended forthese lesions. So complementary quantitative analysis is only recommended for adnexal masses with type II TICs. PMID: 31244278 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Opinions of the Urban Women on Pap test: Evidence from Bangladesh.
Authors: Mustari S, Hossain B, Diah NM, Kar S Abstract Each year, many countries from developed world publishes reports on early cancer detection; which is absolutelyabsent in most developing countries like Bangladesh.Very limited evidence is found on the role and acceptance of Paptest among the women of Bangladesh in determining cervical cancer. More research and updates are needed relating Paptest in early detection of cervical cancer. Thus the purpose of this study is set to assess the opinions of Bangladeshiurbanwomentowardsthe Pap test. A questionnaire-based survey of 400 Bangladeshi urban women was evaluated ...
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Contribution of Genetic Polymorphisms of Inflammation Response Genes on Sporadic Colorectal Cancer Predisposition Risk in Malaysian Patients - A Case Control Study.
Conclusion: We observed an association between variant allele and genotypes of IL-8-251 T>A and TNF-α-308G>A polymorphisms and CRC susceptibility risk in Malaysian patients. These two SNPs in inflammatory responsegenes which undoubtedly contribute to individual risks to CRC susceptibility may be considered as potential geneticpredisposition factors for CRC in Malaysian population. PMID: 31244280 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Expression of miR-9 and miR-200c, ZEB1, ZEB2 and E-cadherin in Non-Small Cell Lung Cancers in Iran.
In this study, expression levels of miR-200cand miR-9, ZEB-1, ZEB-2 and E-cadherin were assessed in 30 non-small cell lung cancers (NSCLCs) by real-timeqPCR. MiR-9 was down-regulated significantly in tumor tissues compared to normal adjacent tissues, while there wasno significant change in expression level of miR-200c. On the other hand, ZEB1 demonstrated significant increaseand ZEB2a decrease at the mRNA level. These results indicate roles for miR-9 and ZEB1 in genesis of lung cancer,although clinico-pathological associations were not evident. Further studies are necessary to assess implications fortreatment of lung cance...
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

MicroRNA Isolation by Trizol-Based Method and Its Stability in Stored Serum and cDNA Derivatives.
In conclusion, the Trizol-basedmethod is efficient as well as economical to use for quantification of circulating miRNAs. In addition, we proposedthat the storage of miRNA-derived cDNAs may be an alternative choice to avoid the stability effect. PMID: 31244282 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Relative Expression of OCT4, SOX2 and NANOG in Oral Squamous Cell Carcinoma Versus Adjacent Non- Tumor Tissue.
CONCLUSION: Based on the present data, decreased expression of SOX2 is correlated with carcinogenesisin the oral cavity and development of OSCC. PMID: 31244283 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Differential Profile of BRCA1 vs. BRCA2 Mutated Families: A Characterization of the Main Differences and Similarities in Patients.
Authors: Fernandes GC, Felicio PS, Michelli RAD, Coelho AS, Scapulatempo-Neto C, Palmero EI Abstract The identification of families at-risk for hereditary breast cancer (BC) is important because affected individualspresent a much higher cancer risk than the general population. The aim of this study was to identify the most importantfactors associated with the presence of a pathogenic BRCA1/BRCA2 mutation. Family history (FH), histopathologicaland immunohistochemical characteristics were compared among BC women with pathogenic BRCA1/BRCA2 variants;VUSs in BRCA1/BRCA2; BRCA1/BRCA2 WT and sporadic BC. The most signifi...
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Effect of the Walking Exercise Program on Cancer-Related Fatigue in Patients with Acute Myeloid Leukemia Undergoing Chemotherapy.
This study aimed to investigate theeffect of the walking exercise program on CRF in patients with AML undergoing chemotherapy. METHODS: In thisquasi-experimental study with a pre- and post-test design, 50 patients with AML undergoing chemotherapy wereselected using a convenience sampling method at a teaching hospital in an urban area of Iran. The intervention includeddaily 30 minutes of planned walking for ten days. Data was collected using a demographic data form and the BriefFatigue Inventory, which were filled out before the intervention, and on the fifth and tenth days of the intervention.Findings: Statistically si...
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Metformin Modulates Cyclin D1 and P53 Expression to Inhibit Cell Proliferation and to Induce Apoptosis in Cervical Cancer Cell Lines.
Authors: Yudhani RD, Astuti I, Mustofa M, Indarto D, Muthmainah M Abstract BACKGROUND: Cervical cancer is one of the most prevalent gynecological cancers worldwide and contributes in highmortality of Indonesian women. The efficacy of chemotherapy as a standart therapy for cervical cancer decreases becauseit frequenly rises adverse effects. Recent studies have found that metformin has a potential anticancer effect mostlythrough reduction of cyclin expression and activation of Activated Adenosine Monophosphate Kinase (AMPK). Thisstudy aimed to investigate the effect of metfomin on expression of cyclin D1 and p53 and ...
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Over-Expression of Cyclooxygenase-2 in Colorectal Cancer Patients.
Authors: Negi RR, Rana SV, Gupta V, Gupta R, Chadha VD, Prasad KK, Dhawan DK Abstract BACKGROUND: Colorectal carcinoma (CRC) is the most common neoplasm of the gastrointestinal tract. COX-2plays an important role in CRC development and is a key target for the regression of colorectal tumorigenesis by nonsteroidalanti-inflammatory drugs. The present study was conducted to examine the relationship of the levels of COX-2in CRC patients with the clinico-pathological parameters and also to assess its usefulness as a potential biomarker fordiagnosis of CRC. METHODS: Prior to surgery, 30 CRC patients were enrolled and...
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Establishment and Characterization of a New Triple Negative Breast Cancer Cell Line from an Iranian Breast Cancer Tissue.
In this study Pari-Institute for Cancer Research (Pari-ICR) was derived from the primary breast tumorof a 36-years old patient with invasive ductal carcinoma. We characterized the cell line by examining morphology,expression of different markers, and functional profile. Immunocytochemistry showed that this cell line does not expressestrogen and progesterone receptors as well as human epidermal growth factor receptor 2 (HER2). Pari-ICR cell lineexpresses high levels of Vimentin, Ezrin, and S100 but does not express EpCAM, Cytokeratin19, Pan-cytokeratin,Nestin, and Desmin. Its doubling time of Pari-ICR was about 22h and was ...
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Overview of the Mutational Landscape in Primary Myelofibrosis and Advances in Novel Therapeutics.
Authors: Gilani JA, Ashfaq MA, Mansoor AE, Abdul Jabbar A, Siddiqui T, Khan M Abstract Primary Myelofibrosis is a BCR-ABL negative myeloproliferative neoplasm with a variety of hematologicalpresentations, including thrombosis, bleeding diathesis and marrow fibrosis. It is estimated to have an incidence of1.5 per 100,000 people each year. Although JAK2 or MPL mutations are seen in PMF, several other mutations haverecently been documented, including mutations in CALR, epigenetic regulators like TET, ASXL1, and 13q deletions.The identification of these mutations has improved the ability to develop novel treatment opti...
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Retrospective Analysis of Cancer Care Performance and Survival Outcome for Nasopharyngeal Carcinoma at a leading Cancer Treatment Centre in Malaysia 2008-2012.
CONCLUSION: SJMC is among the firsthospitals in Malaysia to embark on routine measurement of the performance of its cancer care services and its resultsare comparable to any leading centers in developed countries. PMID: 31244290 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Smoking Perceptions and Practice among Nursing Students in Kabupaten Kupang, Indonesia.
CONCLUSION: This study suggests that smokingprevalence among nursing students is high. Despite most of the students having good smoking-related knowledge andhaving supportive attitudes towards providing smoking cessation services, high smoking prevalence is known to be animpediment to being effective in delivering cessation services. Personal smoking behaviour among nurses needs to beaddressed to encourage critical nursing-led smoking cessation interventions. PMID: 31244291 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Five-Year Overall Survival of Interval Breast Cancers is Better than Non- Interval Cancers from Korean Breast Cancer Registry.
CONCLUSION: ICs occurred unequally in specific provinceand relatively high-educated women in Korea. They were also diagnosed with early-stage breast cancer with a favorablerecurrence risk, and their outcome was better than those of patients with other breast cancers in breast cancer screening. PMID: 31244292 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Post-Operative Concurrent Chemoradiation for Patients with Non-Squamous Cell Carcinoma of Head and Neck: A Retrospective Cohort of the Uncommon Cancers.
CONCLUSION: Post-operative CCRT was associated with better survival inhigh-risk patients with resectable non-metastatic HNnSCCA comparing with post-operative RT alone. Post-operativeCCRT might be considered as a treatment option for these patients. PMID: 31244293 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Family Caregivers' Involvement in Caring with Cancer and their Quality of Life.
Authors: Kilic ST, Oz F Abstract BACKGROUND: Cancer is a chronic disease and a major health problem. It affects both patients and their familycaregivers multidimensionally. The family caregivers may be affected by not only the disease process but also hospitalpolicies, economic difficulties, accessibility and communication of health care service and can be in need of help.This process may affect their quality of life. However, there have not been enough studies on quality of life of familycaregivers of patients with cancer in Turkish culture. Therefore, this study aimed to evaluate the quality of life offamily care...
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Apoptotic Resistance of Metastatic Tumor Cells in Triple Negative Breast Cancer: Roles of Death Receptor-5.
Conclusion: These findings provided important insights regarding the molecular mechanism of apoptosis resistance ofmetastatic tumor cells and can be used for designing a targeted therapeutic strategies in combat with metastatic TNBC. PMID: 31244295 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Identification of FLT3 and NPM1 Mutations in Patients with Acute Myeloid Leukaemia.
CONCLUSION: The optimized in-house PCR assays for thedetection of FLT3-ITD, FLT3-D835 and NPM1 mutations in AML patients were robust, less labour intensive and costeffective. These assays can be used as diagnostic tools for mutation detection in AML patients since identification ofthese mutations are important for prognostication and optimization of patient care. PMID: 31244296 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

The Effect of the Family-Centered Empowerment Model (FCEM) on the Care Burden of the Parents of Children Diagnosed with Cancer.
This study aims todetermine the effect of the Family-Centered Empowerment Model (FCEM) on the care burden of the parents of children,diagnosed with cancer. METHODS: This quasi-experimental study was conducted with 78 parents, having children withcancer. The FCEM was implemented in the intervention group in four stages, namely perceived a threat, self-efficacy,educational participation, and evaluation during four sessions of 20-40 minutes. The control group only received theusual care. The burden of care of the control and intervention groups were measured one month after filling out theinitial questionnaire, and one mo...
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Assessment of the Gail Model in Estimating the Risk of Breast Cancer: Effect of Cancer Worry and Risk in Healthy Women.
CONCLUSION: We identified certain risk factors for breast cancer in our study populationand Gail model is a reliable and useful breast cancer risk prediction model for clinical decision-making. This studycontributes to the body of evidence in order to facilitate early detection and better plan for possible malignancies inTurkish population. PMID: 31244298 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Clinicopathologic Features of Colorectal Polyps in Shahid Beheshti University of Medical Sciences (SBMU).
This study was designed to report epidemiologic findings of polyps in Iranian patients, and predict histology of polyp regarding to demographic and colonoscopic findings. BACKGROUND: Classification of colorectal polyps had been revised in the past two decades and there is a need for polyp categorization in the Iranian Health System. PATIENTS AND METHODS: In this retrospective study, the medical records of patients with colonoscopic diagnosis of polyp in pathology departments of SBMU affiliated teaching hospitals were reviewed. Patient's slides evaluated and demographics findings were assessed. The anatomical locati...
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Smoking History Decreases Survival in Patients with Squamous Cell Carcinoma of the Mouth: A Retrospective Study with 15 Years of Follow-up.
Authors: Colares N, Souza Rodrigues DF, Freitas MO, Dantas TS, Cunha MDPSS, Sousa FB, Barros Silva PG Abstract BACKGROUND: The purpose of this study was to evaluate the influence of smoking history on the clinical-pathological,sociodemographic and prognostic characteristics of patients with oral squamous cell carcinoma (SCC).Materials and Methods: A retrospective cohort study was carried out with the records of 136 smokers with SCC and68 nonsmokers with oral SCC who were diagnosed and treated at Haroldo Juaçaba Hospital (2000-2014). Data onpatient sex, age, race, education level, tumor location, tumor size, ...
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Diagnostic Value of Diffusion Weighted Magnetic Resonance Imaging in Evaluation of Metastatic Neck Lymph Nodes in Head and Neck Cancer: A Sample of Iranian Patient.
Authors: Alamolhoda F, Faeghi F, Bakhshandeh M, Ahmadi A, Sanei Taheri M, Aabbasi S Abstract OBJECTIVE: To evaluate the diagnostic value of DWI in assessment of metastatic neck lymph node in a sample ofIranian patients with Head and Neck cancer. METHODS: 25 patients with 80 neck lymph nodes were analyzed using 1.5 TMRI. DWI was performed with b values of 0 and 1,000 s/mm2. Short axis diameter and ADC values (min, max and mean)were calculated for metastatic and non-metastatic neck LNs and results were compared with histopathological findings.The optimal ADC thresholds were analyzed using receiver coefficient cha...
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Health Insurance and Colorectal Cancer Survival in Khon Kaen, Thailand.
CONCLUSION: The survival ofcolorectal cancer patients in the Universal Coverage Scheme was likely to be poorer than in the Civil Servant MedicalBenefit Scheme. This indicates an urgent need for a national program for colorectal cancer screening in the generalpopulation and access to health insurance. PMID: 31244302 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Eating Habits and Preferences of Polish Women Undergoing Treatment for Breast Cancer.
CONCLUSION: The demonstrated dietary mistakesindicate that actions aiming to promote benefits of undertaking behaviour beneficial for health should also be carriedout among women with breast cancer diagnosis after the completion of treatment. PMID: 31244303 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Progression of Precancerous Cervical Lesion Predicted by p16 Protein Immunohistochemistry in Rajavithi Hospital.
CONCLUSION: Overexpression of p16 protein has the prognostic significance of SIL. Using p16-IHC may help stratify patients aslow-risk and high-risk groups to progression/recurrence CIN2+. PMID: 31244304 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

A Cross-sectional Study of Knowledge, Attitude and Barriers to Colorectal Cancer Screening among Cancer Survivors.
Authors: Huang Y, Soon YY, Ngo LP, Dina Ee YH, Tai BC, Wong HC, Lee SC Abstract INTRODUCTION: Understanding behaviour of cancer survivors is imperative as they are at risk of recurrence or second cancers. Colorectal cancer (CRC) is one of the most common cancers globally. We aim to determine the uptake rate, barriers and predictors of CRC screening among cancer survivors. METHODS: Within a public hospital in Singapore, 150 non-CRC survivors were enrolled. Questionnaire on knowledge, screening behaviour, motivators and barriers towards CRC screening was administered. RESULTS: Majority were survivors of breas...
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Factors Associated with Breast Cancer Awareness in Thai Women.
Conclusion: Despite lower knowledge of breast cancer risk factors and no evidence of better knowledge of signs andsymptoms, we found rural Thai women had considerably better breast cancer awareness behavior. This may be due tothese women's lower levels of perceived barriers to breast cancer screening services. Indeed this suggests, at least inThai women, that interventions aimed at lowering perceived barriers rather than enhancing disease knowledge maybe more successful in engaging women with breast cancer screening services and increasing breast self-examination. PMID: 31244306 [PubMed - in process] (Source: Asian Pac...
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Significance of Serum Adiponectin and Insulin Resistance Levels in Diagnosis of Egyptian Patients with Chronic Liver Disease and HCC.
Conclusion: Insulin Resistance is significantly associated with the development of HCC. Serumlevel of Adiponectin may guard against HCC development among patients with chronic liver disease. PMID: 31244307 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Association of Matrix Metalloproteinase1-1607 1G > 2G Polymorphism and Lung Cancer Risk: An Update by Meta-Analysis.
Association of Matrix Metalloproteinase1-1607 1G>2G Polymorphism and Lung Cancer Risk: An Update by Meta-Analysis. Asian Pac J Cancer Prev. 2019 Jun 01;20(6):1841-1847 Authors: Ma Y, Yang X, Xie YP, Yi C, Zhao F, Huang Y Abstract OBJECTIVE: The association between matrix metalloproteinase1 (MMP1)-1607 1G>2G polymorphism and lung cancerrisk is still inconclusive and inconsistent. We conducted a meta-analysis to estimate the potential relationship betweenMMP1-1607 1G>2G polymorphism and lung cancer risk. METHODS: The comprehensive searches of the PubMed, Webof Science, Medline, CBM, CNKI, We...
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Role of TMPRSS4 Modulation in Breast Cancer Cell Proliferation.
CONCLUSION: TMPRSS4 plays important roles in cancer progression and may beconsidered as a good therapeutic target for cancer gene therapy especially breast cancer. PMID: 31244309 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Difficult Access and Poor Productivity: Mammography Screening in Brazil.
CONCLUSION: These results suggest that the difficulty of the Brazilian population in accessing breast cancer screening through theSUS is not associated with the number of machines available or with the geographical location of the equipment butrather with the insufficient number of mammograms performed. PMID: 31244310 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Information Needs Assessment among Parents of Children with Cancer.
Authors: Motlagh ME, Mirzaei-Alavijeh M, Hosseini SN Abstract BACKGROUND: Parents of children with leukemia should be receiving an extensive amount of information about thecare of their child; the aim of this study was to determine the parents' information needs of children with leukemia.Methods: A cross-sectional study design was used to describe medical, physical, mental and lifestyle informationneeds among parents of children with leukemia. 209 parents of children diagnosed with leukemia in the west of Iran,during winter 2018, voluntarily participated in individual interviews. Data were analyzed by SPSS version ...
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Social Workers in Pediatric Oncology: A Qualitative Study in Iranian Context.
CONCLUSION: In addition to explaining the social workers' experiences andrelated factors, the results emphasize the importance of taking care of service providers to prevent them becomingstressed and exhausted. It is also important to protect patients from the consequences of stressed and exhausted careproviders so further research is recommended to develop specific intervention. PMID: 31244312 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Effect of Pretreatment Platelet Parameters on Survival in Limited Disease Small Cell Lung Cancer.
This study consisted of patients who received CCRT due to LD-SCLC in the oncology clinic between 1997-2017.Examined platelet parameters included total platelet count (TPC), mean platelet volume, platelet distribution width,and platelet-lymphocyte ratio. The cut-off value for TPC was determined as 306x109/U (sensitivity: 62%, specificity:75.5%), where patients below or equal to this level was classified as Group I, and those above as Group II. RESULTS: Thestudy included 90 patients whose mean age was 59 years (range: 42-83) and male ratio was 80.0% (n=72). Nearthree-fourths of patients (74.4%) were at clinical stage III...
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Classification of Skin Disease using Ensemble Data Mining Techniques.
CONCLUSION: The ensemble method used on Dermatology datasets give better performance as compared todifferent classifier algorithms. Ensemble method gives more accurate and effective skin disease prediction. PMID: 31244314 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Low Expression of MicroRNA335-5p Is Associated with Malignant Behavior of Gallbladder Cancer: A Clinicopathological Study.
Authors: Fatima N, Srivastava AN, Nigam J, Raza ST, Rizvi S, Siddiqui Z, Kumar V Abstract BACKGROUND: MicroRNAs (miRNAs) are non-coding RNAs that regulate multiple cellular processes during cancerprogression, identified to be involved in tumorgenesis of several cancers including cancers of digestive system. Howeverits role in gallbladder inflammatory disease (GID) and gallbladder cancer (GBC) has not been well documented.The present study was aimed to investigate the clinical significance of hsa-miRNA-335-5p (miR-335) in GBC andGID. SUBJECTS AND METHODS: This prospective case control study, conducted from July ...
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Awareness about Breast Cancer and Breast Self-Examination among Female Students at the University of Sharjah: A Cross-Sectional Study.
CONCLUSIONS: Although mostparticipants were aware of breast cancer, knowledge about risk factors and warning signs/symptoms was relativelypoor. Knowledge about performing BSE was particularly low. This highlights the importance of increasing awarenessabout breast cancer and BSE among young women in the UAE. PMID: 31244316 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Clinical Features of Breast Cancer Patients with Human T-Cell Lymphotropic Virus Type-1 Infection.
CONCLUSIONS: HTLV-1-positive patients were significantly olderthan HTLV-1-negative patients. It was supposed to be due to the fact that the HTLV-1 infection rate is decreasing. Anyeffect of HTLV-1 infection on breast cancer progression appears to be negligibly small. PMID: 31244317 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

The Relationship of Health Beliefs on the Stage of Mammography Behavior Adoption amongst Women in Kuantan, Pahang.
CONCLUSION: Women inthe action stage are more likely to progress towards maintenance stage as they perceived breast cancer as a disease thatleads to death and that mammogram screening is beneficial in detecting the disease at an early stage. However, womenin the pre-contemplation, relapse and contemplation stage are found unlikely to move towards the maintenance stageas they perceived their risk of getting breast cancer is low. PMID: 31244318 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Association of Glutathione-S-Transferases M1 and T1 Deletional Variants with Development of Oral Squamous Cell Carcinoma: A Study in the South-East of Iran.
CONCLUSION: Null genotypes polymorphisms were more common in OSCC than healthyindividuals. GSTT1 null genotype may be an important genetic factor in the progression of OSCC. PMID: 31244319 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Assessment of Circulating miRNA-17 and miRNA-222 Expression Profiles as Non-Invasive Biomarkers in Egyptian Patients with Non-Small-Cell Lung Cancer.
CONCLUSION: MiRNA-17 and miRNA-222 can be considered as non-invasive biomarkers for detectionof early lung carcinogenesis and metastasis in patients with NSCLC, hence providing a basis for the development ofnovel therapeutic approaches. PMID: 31244320 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Combination of Statins and NSAIDs as a Potential Novel Addition to the Limited Anti-Breast Cancer Weaponry: A True Synergistic Model
Authors: Talaiezadeh A, Papan AM, Nazari P, Mousavi Ghanavati SP, Ramazani A PMID: 31127876 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - May 29, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Micronucleus Assay of Buccal Mucosa Cells in Hairdressers: The Importance of Occupational Exposure
Authors: Ribeiro DA PMID: 31127878 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - May 29, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

No Association between Merkel Cell Polymavirus Infection and Keratoacanthoma in Korean Patients
Conclusions: This supports that KA and MCPyV are not related to each other and MCVyP is not a major factor in the pathogenesis of KA. PMID: 31127879 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - May 29, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Histopathological Patterns and Characteristics of Abnormal Cervical Smear in Madinah Region of Saudi Arabia
This study is the first published research study addressing the screening of cervical cancer in Madinah region of KSA. Aim: To evaluate the abnormal cytological entities detected by cervical Pap smear in Madinah region of KSA and to compare the results with other national and international studies. Methods: This retrospective case-control study was conducted in the Departments of Obstetrics and Gynecology, and Histopathology at the Maternity and Children Hospital (MCH), Madinah, KSA from January 2013 to December 2015. Results: Of the 1594 cases reviewed, only 38 cases (2.4%) had epithelial cell abnormalities. High grade sq...
Source: Asian Pacific Journal of Cancer Prevention - May 29, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

A Review on Dietary Intervention in Obesity Associated Colon Cancer
Conclusion: There are many factors that lead to obesity-associated colon cancer and the mechanisms behind it is still undergoing intensive research. This review aims to scrutinize research as well as reviews that have been previously reported on obesity associated colorectal cancer and the beneficial effects of including antioxidants-rich foods such as vegetables and fruits in the diet to reduce the risk of obesity associated colorectal cancer. PMID: 31127882 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - May 29, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Association of Dietary Intake Ratio of n-3/n-6 Polyunsaturated Fatty Acids with Breast Cancer Risk in Western and Asian Countries: A Meta-Analysis
Conclusion: This analysis confirmed association of dietary intake ratio of n-3/n-6 PUFAs with breast cancer risk in Western and Asian countries. Higher dietary intake ratio is associated with lower risk of breast cancer in Asian countries rather than Western countries. This study suggests increasing dietary intake ratio n-3/n-6 PUFAs will provide benefit for breast cancer prevention. PMID: 31127884 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - May 29, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research