Educational Interventions for Cervical Cancer Screening Behavior of Women: A Systematic Review
Conclusions: Our results showed that the different interventions and health behavior change frameworks provide an effective base for cervical cancer prevention. Heath providers can chose educational methods based on the particular client situations. PMID: 29693331 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Association of BRCA1 Promoter Methylation with Breast Cancer in Asia: A Meta- Analysis
Authors: Nindrea RD, Harahap WA, Aryandono T, Lazuardi L Abstract Objective: The aim of this study was to determine the degree of association of BRCA1 promoter methylation with breast cancer in Asia. Methods: The study sample for the present meta-analysis was provided by published research articles on associations of BRCA1 promoter methylation with breast cancer in Asia accessed through databases on PubMed, ProQuest and EBSCO published between 1997 and November 2017. Pooled odds ratios (OR) were calculated with fixed and random-effect models. Data were processed using Review Manager 5.3 (RevMan 5.3). Results: Of a ...
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Patient Reported Weight Loss Predicts Recurrence Rate in Renal Cell Cancer Cases after Nephrectomy
This study included all patients with RCC who underwent nephrectomy from 2004 to 2013 at our centre. Recurrence-free survival (RFS) was calculated from the date of surgery to date of recurrence or death. The Cox regression model was applied to identify significant prognostic factors. Results: Overall a total of 292 patients were included. Median age was 50 years (range 19-84 years), with a male:female ratio of 3:1. Radical and partial nephrectomy were performed for 276 (94.5%) and 16 (5.5%) patients, respectively. Clear cell was most common histological subtype (71.2%) and T1, T2, T3 and T4 stages accounted for 89 (30.5%),...
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Preoperative Monocyte Count as a Mirror of Tumor Characteristics and Likelihood of Recurrence in Endometrial Carcinoma Cases
Authors: Modares Gilani M, Kazemi Z, Zamani N, Shahrami H, Ghahghaei-Nezamabadi A, Sheikham S Abstract Background: Recently preoperative hematologic parameters have attracted attention for their capacity to predict tumor characteristics and recurrence. Considering the established role of tumor-associated macrophages (TAM) in the tumor microenvironment, we evaluated the role of the preoperative monocyte count as a surrogate for TAM. Methods: We retrospectively reviewed 166 patients with histopathologically proven endometrial cancers from January 2011 to March 2015 and assessed any association of preoperative monocyt...
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Serum CXCL12, but not CXCR4, Is Associated with Head and Neck Squamous Cell Carcinomas
Conclusion: For the first time, our findings demonstrate a significant association between serum CXCL12 but not CXCR4 levels and HNSCCs. PMID: 29693336 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Impact of Mesenchymal Stem Cells and Vitamin D on Transforming Growth Factor Beta Signaling Pathway in Hepatocellular Carcinoma in Rats
Authors: Saad El-Din S, Fouad H, Rashed LA, Mahfouz S, Hussein RE Abstract Background: Transforming growth factor-beta (TGF-β) signaling is recognized as being critical for carcinogenesis. Vitamin D has proved to exert numerous tumor suppressive effects. Effects of bone marrow derived mesenchymal stem cells (BM-MSCs) on tumor progression are still controversial. The present study was conducted to evaluate the effects of BM-MSCs and vitamin D on TGF-β signaling in an experimental hepatocellular carcinoma (HCC) model in rats. Materials and Methods: The study was conducted on fifty female white albino rats d...
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Sirt1 Gene Expression and Gastric Epithelial Cells Tumor Stage in Patients with Helicobacter pylori Infection
In this study, sirt1 and sirt2 genes expression in gastric cancers was surveyed with reference to H. pylori status. Methods: Stomach biopsies were collected from 50 gastric cancer patients, 25 H. pylori-positive and 25 H. pylori-negative as determined by the urea rapid test. Tumor grade was determined by a pathologist. After total RNA extraction from gastric cancer biopsy samples and cDNA synthesis, sirt1 and sirt2 genes expression levels were determined by Real Time PCR and ΔΔCT methods. Results: There was no statistically significant link between H. pylori infection and sirt1 (P
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Clausenidin Induces Caspase 8-Dependent Apoptosis and Suppresses Production of VEGF in Liver Cancer Cells
Authors: Waziri PM, Abdullah R, Rosli R, Omar AR, Abdul AB, Kassim NK, Malami I, Etti IC, Sani JM, Mohd Lila MA, Abdullah JFF Abstract Clausena excavata Burm f. is used by traditional healers to treat cancer patients in South East Asia. The use of the plant and its compounds is based on Asian folklore with little or no scientific evidence supporting the therapeutic efficacy The current study aimed to determine the effect of pure clausenidin isolated from C. excavata on caspase-8-induced cell death as well as angiogenesis in the HepG2 hepatocellular carcinoma cell line. Caspase-8 and extrinsic death receptor protein...
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Detection of a 4-bp Insertion/deletion Polymorphism within the Promoter of EGLN2 Using Mismatch PCR-RFLP and Its Association with Susceptibility to Breast Cancer
Authors: Hashemi M, Danesh H, Bizhani F, Sattarifard H, Hashemi SM, Bahari G Abstract It has been shown that a 4-bp insertion/deletion (ins/del) polymorphism of EGLN2 influences the risk of several cancers. However, to date, no study has inspected the impact of the 4-bp ins/del polymorphism on breast cancer (BC) risk. A case-control study, including 134 breast cancer patients and 154 healthy women, was here conducted to examine the possible association between EGLN2 4-bp ins/del polymorphism and BC risk in a southeast Iranian population. A mismatched polymerase chain reaction-restriction fragment length polymorphis...
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Screening and Identification of Peptides Specifically Targeted to Gastric Cancer Cells from a Phage Display Peptide Library
Conclusion: Selection and characterization of individual clones may give us specifically binding peptides, but more importantly, data extracted from eluted phage clones may be used to design theoretical peptides with better binding properties than even experimentally selected ones. Both peptides, experimental and designed, may be potential candidates to be developed as useful diagnostic or therapeutic ligand molecules in gastric cancer research. PMID: 29693344 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Comparative Cost-Effectiveness Analysis of Two Different Two-Dose Human Papillomavirus Vaccines in Malaysia
Conclusions: In Malaysia, the use of AS04-HPV-16/18v, in addition to screening, was modelled to be dominant over 4vHPVv, with greater estimated CC benefits and lower costs. PMID: 29693347 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Contrast-Enhanced Perfusion MR Imaging to Differentiate Between Recurrent/Residual Brain Neoplasms and Radiation Necrosis
Conclusion: DSC MR perfusion is a promising technique in differentiating recurrent brain tumors from radiation necrosis as it has acceptable spatial resolution and can be routinely performed in the same settings after conventional MRI. PMID: 29693348 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Effecst of Patho- Biological Factors on the Survival of Recurrent Breast Cancer Cases
Conclusion: The results of this study enhance our knowledge of effects of different factors on survival of patients after breast cancer recurrence. Thus, they may be used to inform treatment choice. PMID: 29693352 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Proliferative Index (Ki67) for Prediction in Breast Duct Carcinomas
Authors: Ahmed ST, Ahmed AM, Musa DH, Sulayvani FK, Al-Khyatt M, Pity IS Abstract Background and objectives: To date, many tumor markers have been used to predict prognosis and therapeutic response in patients with breast cancer. The well established and routinely applied tumor markers are the estrogen-receptor, progesterone-receptor and Her2/neu-receptor. In the current study, we aimed to highlight any association of the proliferation index (Ki67) in breast infiltrative duct carcinoma with the tumor grade, tumor size and nodal status in addition to hormone receptor status. Tissue sections were stained immunohistoc...
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Metagenomics of Microbial Communities in Gallbladder Bile from Patients with Gallbladder Cancer or Cholelithiasis
Authors: Tsuchiya Y, Loza E, Villa-Gomez G, Trujillo CC, Baez S, Asai T, Ikoma T, Endoh K, Nakamura K Abstract Salmonella typhi and Helicobacter infections have been shown to increase risk of gallbladder cancer (GBC), but findings have been inconsistent. Other bacterial infections may also be associated with GBC. However, information on microbial pathogens in gallbladder bile of GBC patients is scarce. We aimed to investigate the microbial communities in gallbladder bile of patients with GBC and cholelithiasis (CL). Seven GBC patients and 30 CL patients were enrolled in this study. Genomic DNA was extracted from bi...
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Identification of Key Candidate Genes and Pathways in Endometrial Cancer by Integrated Bioinformatical Analysis
Authors: Liu L, Chen F, Xiu A, Du B, Ai H, Xie W Abstract Endometrial Cancer is the most common female genital tract malignancy, its pathogenesis is complex, not yet fully described. To identify key genes of Endometrial Cancer we downloaded the gene chip GSE17025 from the Gene Expression Omnibus database. Differentially expressed genes (DEGs) were identified through the GEO2R analysis tool. Functional and pathway enrichment analysis were performed for DEGs using DAVID database. The network of protein–protein-interaction (PPI) was established by STRING website and visualized by Cytoscape. Then, functional and ...
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Synergistic Growth Inhibitory Effects of Chrysin and Metformin Combination on Breast Cancer Cells through hTERT and Cyclin D1 Suppression
Conclusion: The conmbination of metformin and chrysin suppressing hTERT and cyclin D1 gene expression might offer an appropriate approach for breast cancer therapy. PMID: 29693804 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

The Impact of Perceived Barriers on Self-Efficacy for HPV Preventive Behavior
Conclusion: This study showed the importance of considering perceived barriers of HPV preventive behavior related to self-efficacy. However, different from HBM, modifying factors, such as knowledge, perceived susceptibility, and individual demographics were not related to self-efficacy. Based on these findings, future research should investigate self-efficacy and HPV preventive behavior among individuals who do not participate in HPV preventive behavior. PMID: 29693957 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Psychometric Properties of the Farsi Version of “Spiritual Needs Questionnaire” for Cancer Patients in Iran: A Methodological Study
Conclusion: The modified Farsi version of the SpNQ shows good psychometric properties for patients and can be used to investigate the spiritual needs of Iranian cancer patients. PMID: 29693961 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Determinants of Breast Cancer Screening by Mammography in Women Referred to Health Centers of Urmia, Iran
This study was aimed to evaluate breast cancer screening determinants in women referred to health centers of Urmia for mammography in 2017. Materials and Methods: In this descriptive-analytic cross-sectional study, 348 women referred to health centers of Urmia were selected using multistage sampling. Data were collected using a standard questionnaire for mammography screening determinants, with a checklist including demographic characteristics, family, social and economic factors and midwifery background. Analysis was with SPSS software version 20for descriptive and inferential statistic tests, P
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Quality of Life of Nepalese Women Post Mastectomy
Conclusion: Based on the study findings, counseling, and a structured educational programme is recommended to improve the QOL of women after a mastectomy. PMID: 29693969 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Expression of CDK6 in Oral Squamous Cell Carcinomas
Conclusion: Overexpression of CDK6 observed in OSCC points to a role for this protein in oral carcinogenesis. PMID: 29693970 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Assessing Breast Cancer Risk with an Artificial Neural Network
Conclusion: ANN has potential applications as a decision-support tool to help underperforming practitioners to improve the positive predictive value of biopsy recommendations. PMID: 29693975 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Evaluation of Osteopontin as a Biomarker in Hepatocellular Carcinomas in Egyptian Patients with Chronic HCV Cirrhosis
Conclusion: Serum OPN is highly suggested to be a professional candidate for HCC early diagnosis, with a diagnostic ability and accuracy equal or higher than for AFP. PMID: 29693976 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Diagnostic Yield of Transbronchial Biopsy in Comparison to High Resolution Computerized Tomography in Sarcoidosis Cases
This study aimed to evaluate the diagnostic yield of fiberoptic bronchoscopic (FOB) transbronchial biopsy and its relation with quantitative findings of high resolution computerized tomography (HRCT). A total of 83 patients, 19 males and 64 females with a mean age of 45.1 years diagnosed with sarcoidosis with complete records of high resolution computerized tomography were retrospectively recruited during the time period from Feb 2005 to Jan 2015. High resolution computerized tomography scans were retrospectively assessed in random order by an experienced observer without knowledge of the bronchoscopic results or lung func...
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Association between Helicobacter pylori Infection and Cardiovascular Risk Factors among Patients in the Northern Part of Afghanistan: a Cross-Sectional Study in Andkhoy City
Conclusions: Our study indicated that H. pylori infection was significantly associated with DM and elevated BMI levels in patients from an outpatient clinic in Andkhoy, Afghanistan. More aggressive measures, including DM, obesity control, and H. pylori eradication are needed. PMID: 29693980 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 27, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Alcohol Consumption and Sexual Risk Behaviour among Jamaican Adolescents
Conclusion: Lifetime, past one year and past one month alcohol consumption among the students were not risk factors for sexual risk behavior (non-condom use) among Jamaican adolescents. PMID: 29681143 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 25, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

A School-Based Study of the Influence of Students ’ Relationship with Teachers on Their Cigarette Smoking Behaviour in Jamaican
Conclusion: Students’ relationship with their teachers has a strong influence on cigarette smoking. Students with very good relationship with teachers were significantly less likely to report smoking cigarette in the past month. PMID: 29681144 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 25, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Does Risk Perception Affect Alcohol Consumption among Secondary School Students in Jamaica?
Conclusion: Risk perception of the harmfulness of alcohol significantly affects alcohol use among secondary school students in Jamaica. Males, 12 years or younger, who had good relationship with mothers, were significantly less likely to use alcohol in past month PMID: 29681145 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 25, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Single Parent Family Structure as a Predictor of Alcohol Use among Secondary School Students: Evidence from Jamaica
Conclusion: Family structure is an independent predictor of alcohol use among high school students in Jamaica. Being from single-parent families, married-parent and common- law parent families were significantly associated with increased likelihood for lifetime alcohol use. PMID: 29681146 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 25, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Are Adolescents likely to Start Smoking Early if Their Parents are Smokers? A Study of Jamaican High School Students
Conclusion: Parental smoking cigarette smoking status was not a predictor of early age of cigarette smoking initiation among Jamaican adolescents. PMID: 29682917 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 25, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

A Population-based Analysis of the Influence of Religious Affiliation on Alcohol Consumption among Jamaicans
Conclusion: Being of Christian religion was significantly, positively associated with past year and past month alcohol consumption. Male gender and being employed were also risk factors for lifetime alcohol consumption. PMID: 29682918 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 25, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Risk Factors Associated with Frequent Alcohol Binge Drinking among Jamaicans: Does Gender Matter?
Conclusion: Risk factors for frequent binge drinking differed by gender; being employed was a risk factor for males while having primary (or lower) education was a risk factor for females. PMID: 29682919 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 25, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Investigating the Role of Alcohol in Behavioural Problems at School among Secondary School Students in Barbados
Conclusion: Neither past year nor past month alcohol consumption by students was associated with frequent behavioural problems at school. Students who were younger than 17 years, and who had a relationship with their teachers that was not very bad were significantly less likely to engage in frequent behavioural problems. PMID: 29682920 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 25, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Alcohol Drinking among Primary School Children in Trinidad and Tobago: Prevalence and Associated Risk Factors
Conclusion: Being a male student, not living with father, and father attaining either primary or secondary education level were significantly associated with increased likelihood for lifetime alcohol use. However, children between 8 – 11 years were less likely to consume alcohol. PMID: 29682921 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 25, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Parental Alcohol Drinking Habit as a Predictor of Alcohol Use among Secondary School Students in Barbados
Conclusion: Having fathers who drink only on weekend, sometimes during the week and every day were significantly positively associated with alcohol use in the past month. Having mothers who drink only on special occasion was a risk factor for past year and past month alcohol use. However, having mothers who drin PMID: 29682922 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 25, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Ecballium Elaterium for Gastrointestinal Cancer
Authors: Mazokopakis EE PMID: 29579786 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 29, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Significant SNPs Related to Telomere Length and Hepatocellular Carcinoma Risk in Chronic Hepatitis B Carriers
Authors: Mohamadkhani A, Pourasgari M, Poustchi H Abstract Chronic hepatitis B virus (HBV) infection increases the risk of developing cirrhosis and hepatocellular carcinoma (HCC) with suspected interactions between virus replication and host immune responses. A number of reports have suggested that telomerase function may be involved in chronic hepatitis B (CHB) pathogenesis, but positive or negative associations with HCC risk remain for discussion. Mean telomere length is an indicator of biological aging and it has been reported that reduction in NBV carriers compared to normal individuals. In somatic cells, telom...
Source: Asian Pacific Journal of Cancer Prevention - March 29, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Risk Factors for Gastric Cancer: A Systematic Review
Conclusion: Several environmental and genetic factors are involved in the development of gastric cancer. Regarding the role of changes in ‘diet and lifestyle’, considering appropriate nutrition and improving the level of education and awareness of people is vital for early diagnosis and timely treatment of this disease, especially in people with a family history and genetic predisposition. PMID: 29579788 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 29, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Risk Factors for Cholangiocarcinoma in Thailand: A Systematic Review and Meta-Analysis
Conclusion: There are unique risk factors of cholangiocarcinoma in Thailand, including age, Opisthorchis viverrini infection, eating raw cyprinoid fish, family history of cancer, liquor consumption, and taking praziquantel. PMID: 29579789 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 29, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Osteopontin b and c Splice isoforms in Leukemias and Solid Tumors: Angiogenesis Alongside Chemoresistance
Authors: Mirzaei A, Mohammadi S, Ghaffari SH, Yaghmaie M, Vaezi M, Alimoghaddam K, Ghavamzadeh A Abstract Osteopontin (OPN) is a glycoprotein involved in regulation of various influences on tumor progression, such as cellular proliferation, apoptosis, angiogenesis, and metastasis. Vascular endothelial growth factor (VEGF) is a secreted molecule supporting angiogenesis in various cancers through activation of the PI3K/AKT/ERK1/2 pathway. OPN and VEGF have a number of isoforms with various activities. In spite of the well-defined association between OPN and VEGF isoform expression and cure rate for solid tumors, ther...
Source: Asian Pacific Journal of Cancer Prevention - March 29, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Knowledge, Attitudes and Practices Regarding Breast Cancer amongst Lebanese Females in Beirut
This study aimed to assess the level of breast cancer knowledge, attitudes and screening practices in Lebanese females, and identify their socio-demographic determinants as well as barriers to mammography use. Methods: This cross-sectional study was conducted with 371 Lebanese females residing in Beirut aged 18-65 with no history of breast cancer. The questionnaire applied was adapted from Stager and Champion. The overall knowledge score was determined with sections on general knowledge, curability, symptoms, and screening; the overall attitude score concerned attitudes towards breast cancer, screening, and barriers; and t...
Source: Asian Pacific Journal of Cancer Prevention - March 29, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Effects of an Educational Program for Prostate Cancer Prevention on knowledge and PSA Testing in Men Over 50 Years old in Community Areas of Shiraz in 2016
Authors: Molazem Z, Ebadi M, Khademian M, Zare R Abstract Background and Objectives: Prostate cancer was reported to be the second cause of cancer death in men in 2013. Studies have shown that those with higher knowledge levels are much more likely to undergo prostate cancer screening. The present study was aimed to determinate the effect of an educational program for prostate cancer prevention on knowledge and prostate-specific antigen (PSA) testing in men over 50 years old in community areas of Shiraz. Methods: This clinical trial was conducted among 93 men over 50 years old who were randomly divided into an inte...
Source: Asian Pacific Journal of Cancer Prevention - March 29, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Comparative Evaluation of a 6MV Flattened Beam and a Flattening Filter Free Beam for Carcinoma of Cervix – IMRT Planning Study
Conclusions: 6MV flattened and flattening filter free photon beams produce comparable plans by IMRT . FFF beams allow time efficient treatment delivery and may help reduce the risk of secondary malignances in carcinoma cervix cases. PMID: 29580032 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 29, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Evaluation the Anti-Cancer Effect of PEGylated Nano-Niosomal Gingerol, on Breast Cancer Cell lines (T47D), In-Vitro
Conclusion: The results showed that IC50 of the formulation of PEGylated nanoniosomal Gingerol is less than the standard drug. It seems, the cause of this phenomenon is due to the effect of Polyethylene glycol, in more stability and slower drug release, in the formulation of PEGylated niosome. Also, Polyethylene glycol makes increase in the drug dealing and its greater influence with the target cell. In this study, more than 76% of the Gingerol drug in PEGylated nanoniosomal formulation were enclose. Also, we could reduce the amount of drug release, as much as possible. PMID: 29580033 [PubMed - in process] (Source: Asi...
Source: Asian Pacific Journal of Cancer Prevention - March 29, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Risk Factors, Biomarkers, Etiology, Outcome and Prognosis of Ischemic Stroke in Cancer Patients
Authors: Sorgun MH, Kuzu M, Ozer IS, Yilmaz V, Ulukan C, Cotur Levent H, Tezcan S, Rzayev S, Rawandi A, Bakırarar B, Isikay CT Abstract Introduction: Cerebrovascular disease is the second most common complication in individuals with tumours. The aim of this study was to investigate risk factors, biomarkers, etiology and prognosis of ischemic stroke in cancer patients (ISCPs). Methods: The medical records of 619 consecutive patients who were admitted with acute ischemic stroke from January 2012 to November 2014 were retrospectively evaluated. The patients were divided into two groups (group 1, patients with an acti...
Source: Asian Pacific Journal of Cancer Prevention - March 29, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Fluorescence in Situ Hybridization (FISH) for Differential Diagnosis of Soft Tissue Sarcomas
Conclusion: FISH is a useful adjunct in the diagnostic assessment of different types of soft tissue sarcomas. It is easy to set up, is relatively inexpensive and has the ability to diagnose sarcomas with great accuracy, especially in cases which can not be accurately classified even after thorough histological and immunohistochemical evaluation. It may play a very important role in the accurate diagnosis and correct management of patients. PMID: 29580035 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 29, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Analysis of the Expression of Surface Receptors on NK Cells and NKG2D on Immunocytes in Peripheral Blood of Patients with Nasopharyngeal Carcinoma
Authors: Xu Y, Zhou R, Huang C, Zhang M, Li J, Zong J, Qiu S, Lin S, Chen H, Ye Y, Pan J Abstract Background: The aberrant expression of surface receptors on immunocytes may represent potential markers of tumor escape for nasopharyngeal carcinoma (NPC). The aim of this study was to investigate the expression of representative receptors on natural killer (NK) cells and NK group 2, member D (NKG2D) on immunocytes in the peripheral blood of patients with NPC. Methods: Patients (n = 64) with NPC prior to initiation of treatment were defined as the study group. Healthy volunteers (n = 31) served as the control group. Th...
Source: Asian Pacific Journal of Cancer Prevention - March 29, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Epigenetic Downregulation and Growth Inhibition of IGFBP7 in Gastric Cancer
Conclusion: Our data suggest that IGFBP7 functions as a tumor suppressor in gastric cancer via an epigenetic pathway. PMID: 29580038 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 29, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Impact of Parents and Peers Smoking on Tobacco Consumption Behavior of University Students
Conclusions: Peers had a stronger impact than parents and both parents and peers had greater influence on males than on females. Interestingly, almost 80% of the smoking students did not have smoking parents or peers, which leaves the question unanswered of why they started smoking in the first place. Actions at a societal level should be taken into consideration to prevent smoking and thus help create a non-smoking generation. PMID: 29580039 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 29, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research