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Statin Use and Liver Cancer Risk: A Meta-Epidemiological Study of Retrospective Cohort Studies by the Types of Constructed Cohort
CONCLUSION: The lack of statistical significance in NPo supports the argument that the conclusions of existing systematic reviews on RSC have low validity. It is necessary to conduct a subgroup meta-analysis of the NPo, NPa, and HPa proposed in this study when conducting a systematic review of RSCs, which will evaluate various outcomes of a specific drug intake with time-varying exposure.PMID:38546060 | DOI:10.31557/APJCP.2024.25.3.777 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Jong-Myon Bae Source Type: research

Risk-Stratified Breast Cancer Screening in Malaysia: Challenges and Opportunities
CONCLUSION AND RECOMMENDATION: Identifying a valid and appropriate risk model tailored to the population profile and needs of Malaysian women and conducting a pilot project of risk-stratified screening, guided by implementation science would provide lessons and insights for policymakers, health service managers, and public and primary health care professionals. The results of these activities would increase the likelihood that decisions and plans would lead to the successful implementation in Malaysia of a sustainable and effective breast cancer screening strategy that incorporates a patient-sensitive, risk-stratified appr...
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Mila Nu Nu Htay Tin Tin Su Michael Donnelly Source Type: research

Evidence of Knowledge, Attitude, and Practice Regarding Human Papilloma Virus Vaccination at the Community Level in India: A Systematic Review and Meta-analysis
CONCLUSION: The knowledge, attitude, and coverage of the HPV vaccine were low in India. It suggests effective strategies to improve knowledge and attitudes towards HPV vaccination in India.PMID:38546062 | DOI:10.31557/APJCP.2024.25.3.793 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Debkumar Pal Bimal Kumar Sahoo Manish Taywade Shampa Maji Source Type: research

Meta-Analysis of Incidence and Mortality of Firefighter Cancer: An Update on Emerging Science
CONCLUSIONS: The findings underscore the global cancer burden among firefighters, and indicate that geographically stratifying studies afford a more nuanced risk perspective. Further research should investigate why US firefighters exhibit higher cancer mortality rates compared to international counterparts.PMID:38546063 | DOI:10.31557/APJCP.2024.25.3.801 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Sara A Jahnke Nattinee Jitnarin Christopher K Haddock Christopher Kaipust Walker S Carlos Poston Brittany S Hollerbach Carolyn Crisp Brittni Naylor Metoyer Source Type: research

Human Papillomavirus Vaccine Awareness and Acceptability for Primary Prevention of Cervical Cancer in Pakistan: A Cross-Sectional Study
CONCLUSION: It is important to address the knowledge gaps existing in the community about HPV vaccine acceptability and barriers against it for the successful rollout of the HPV vaccination program in Pakistan. Mass awareness campaigns about HPV, HPV vaccine, and cervical cancer are needed to increase the acceptability of HPV vaccine among public at the time of reintroducing HPV vaccine.PMID:38546064 | DOI:10.31557/APJCP.2024.25.3.813 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Uzma Shamsi Fahad Zahid Ali Bin Abdul Jabbar Muhammad Daniyal Musharraf Fatima Gauhar Inaara Akbar Maryam Sherwani Waiz Kamran Bhatti Etisham Ul Haq Chaudhary Subhan Sadiq Ayesha Niaz Shaikh Fareeha Shaikh Source Type: research

Prevalence of BK and JC Polyomaviruses among Patients with Breast Cancer
DISCUSSION: The findings of the current investigation demonstrate that there was an absence of JC virus detection in the breast biopsy. Additionally, a small fraction of patients diagnosed with ductal carcinoma exhibited a low prevalence of genotype IV polyomavirus BK at a rate of 2%. However, in order to gain a more comprehensive understanding of the incidence of BKV and JCV in breast cancer, a substantial number of breast samples must undergo investigation.PMID:38546065 | DOI:10.31557/APJCP.2024.25.3.821 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Zohreh Alipour Gholam Abbas Kaydani Manoochehr Makvandi Mahsa Javadi Abdolhosein Talaeizadeh Source Type: research

Impact of Genetic Polymorphisms in NF- ĸB2 and TRAF3 Genes on Response to Bortezomib-Based Therapy in Multiple Myeloma Patients
CONCLUSION: The study findings underscore a significant association between genetic polymorphisms and treatment response outcomes, suggesting their utility in prognostic determinations and clinical outcomes prediction in multiple myeloma patients.PMID:38546066 | DOI:10.31557/APJCP.2024.25.3.829 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Nidhi Sood Abdoul Hamide Biswajit Dubashi Yadav Nisha Jayanthi Mathaiyan A K Munirajan Prasanth Ganesn Smita Kayal Source Type: research

A Comparative Analysis on the Potential Anticancer Properties of Tetrahydrocannabinol, Cannabidiol, and Tetrahydrocannabivarin Compounds Through In Silico Approach
CONCLUSION: Overall, in silico predictions of the three cannabinoid compounds revealed that they are good candidates for oral drug formulation. Among the three cannabinoids, THCV is an excellent anticancer aspirant for future chemotherapy with the most favorable results in drug-likeness and ADMET analysis, pharmacological properties evaluation, and cytotoxicity assessment results. Further study on bioevaluation of compounds is needed to elucidate their potential pharmacological activities.PMID:38546067 | DOI:10.31557/APJCP.2024.25.3.839 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Angelica A Gallardo Mikaela Rose Gutierrez Lyka Alexandrea J Gomez Patricia Arielle O Delos Reyes Sophia Allison A Dones Maria Mikaela U Dumbrique Heather Eena Lim Maria Isabel H Liquido Mary Margaret L Macawile Ella Denese Anne B Maglaqui Angelica Mae G Source Type: research

High P16INK4A Expression, Keratinizing Features, and Surgical Margin-Free Status are Associated with Improved Survival in Patients with Oral Squamous Cell Carcinomas
CONCLUSION: P16INK4A positive staining, early stages, negative cervical lymph node infiltration, and free-surgical margins are associated with better prognosis in OSCC patients. The study emphasizes the importance of early detection and the potential use of p16INK4A and other clinical variables to stratify OSCC patients with high risks of recurrence and worse overall survivals.PMID:38546068 | DOI:10.31557/APJCP.2024.25.3.857 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Sumadi Lukman Anwar Ery Kus Dwianingsih Setyani Puji Lestari William Sugandhi Roby Cahyono Gizza Dandy Pradana Source Type: research

Exploring Gender Disparities in Factors Influencing Colorectal Cancer Screening Compliance in Singapore
CONCLUSION: Low compliance with CRC screening was observed in Singapore. Targeted interventions should address gender-specific factors and highlight CRC screening guidelines as a crucial component of cancer education for entire screening eligible population in order to improve CRC screening compliance.PMID:38546069 | DOI:10.31557/APJCP.2024.25.3.867 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Qing Huang Li Ying Tan Source Type: research

Determinants of Quit Attempts and Short-Term Abstinence among Smokeless Tobacco Users in India: Global Adult Tobacco Survey, 2016-17
CONCLUSION: Quit advice by healthcare providers is an influential determinant of a quit attempt, and this intervention needs to be scaled up. The media messages and warning labels were effective among those who considered quitting after noticing them. Cessation methods can help prolong the abstinence from smokeless tobacco, but the reach of cessation methods is limited.PMID:38546070 | DOI:10.31557/APJCP.2024.25.3.875 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Nilesh C Gawde Zahiruddin Quazi Syed Source Type: research

Identification of Hub Genes and Potential Pathogenesis in Gastric Cancer Based on Integrated Gene Expression Profile Analysis
CONCLUSION: SPP1, INHBA, MMP7, THBS2, and FAP were identified as prospective biomarkers and therapeutic targets for GC that might be utilized for prognostic evaluation and scheme selection.PMID:38546071 | DOI:10.31557/APJCP.2024.25.3.885 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Hung Luu Truong Thanh Tien-Manh Hoang Hieu Hoang Van Source Type: research

Integrative Bioinformatics Analysis Reveals Potential Target Genes and PTEN Signaling in Breast Cancer and Effect of Zingiber officinale (Ginger) and Allium sativum (Garlic) extract on It
CONCLUSION: Taken together, we introduce a number of novel promising diagnostic biomarkers for breast cancer. The use of garlic and ginger in the treatment of cancer can be useful. This action is probably through the antioxidant mechanism, and regulation of the expression of cancer related genes such as PTEN.PMID:38546072 | DOI:10.31557/APJCP.2024.25.3.893 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Katayoon Sheybatzadeh Seyed Ali Asghar Moshtaghie Kahin Shahanipour Fereshteh Golab Source Type: research

Exploring the Role and Prognostic Value of TMEM208 in Head and Neck Squamous Cell Carcinoma
CONCLUSION: In conclusion, TMEM208 holds promise as a prognostic indicator for HNSCC and is closely related to ICI treatment.PMID:38546073 | DOI:10.31557/APJCP.2024.25.3.909 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Jing Yang Tao Song Source Type: research

Cytotoxicity and Apoptosis Studies of Brucein D against T24 Bladder Cancer Cells
CONCLUSION: BrD has shown a cytotoxic effect against T24 bladder cancer cells. Hence, it is a promising natural compound for the management of bladder cancer by induction of apoptosis through activation of the intrinsic pathway, with low toxicity to normal cells.PMID:38546074 | DOI:10.31557/APJCP.2024.25.3.921 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Pandu Ishaq Nandana Haerani Rasyid Prihantono Prihantono Ika Yustisia Lukman Hakim Agussalim Bukhari Eka Sunarwidhi Prasedya Source Type: research