Curcumin Inhibits the PPAR δ-p-Akt-GLUT1 Pathway and Ameliorates the Antiproliferative Effects of Doxorubicin in MDA-MB-231 Cells
CONCLUSION: Our study demonstrates that regulation of GLUT1 by curcumin via the PPARδ/Akt signaling improves the efficacy of doxorubicin by promoting its growth inhibitory effects in MDA-MB-231 cells.PMID:38546086 | DOI:10.31557/APJCP.2024.25.3.1035 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Padmamalini Thulasiraman Marie Foret Renu Pandit Kathleen McAlister Source Type: research

Diagnostic Performance of Epithelial Cell Adhesion Molecule for Early Detection of Hepatocellular Carcinoma Among HCV High-Risk Patients
CONCLUSION: EpCAM-HCC score could replace AFP during screening of HCV patients and early detection of HCC.PMID:38546087 | DOI:10.31557/APJCP.2024.25.3.1045 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Rania Nasser Mahdi Al Haddad Mohamed M El-Kassas Fateheya M Metwally Hatem A El-Mezayen Aml El-Sharkawy Source Type: research

Geospatial Patterns of Non-Melanoma Skin Cancer in Relation to Climate Changes in Iran
CONCLUSION: The detection rate of skin cancer increases from north to south and from west to east.PMID:38546088 | DOI:10.31557/APJCP.2024.25.3.1053 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Michael Aryan Kya Source Type: research

In vitro Evaluation of Anti-Cancer Potential of Different Solvent Extracts Derived from Clerodendrum Infortunatum Linn against Cervical Cancer
CONCLUSION: Notably, Clerodendrum infortunatum exhibited the ability to initiate early apoptosis, halt the cell cycle at the S and G2M phases, and diminish levels of reactive oxygen species significantly. The gene expression analysis revealed an influence on the BCL-2 gene. To sum up, this research underscores the encouraging cytotoxic and antioxidant attributes of Clerodendrum infortunatum, implying its potential for cervical cancer treatment.PMID:38546089 | DOI:10.31557/APJCP.2024.25.3.1065 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Jayshree V Changade Harsha Thanvi Chandrashekhar Raut Manasi Chavan Prachi Prasad Vaibhav S Ladke Source Type: research

Prediction and Diagnosis of Breast Cancer Using Machine and Modern Deep Learning Models
CONCLUSION: Among the most commonly used classifier models, CN2 rule and GB performed better than other models. However, MLP from deep learning produced the greatest overall performance.PMID:38546090 | DOI:10.31557/APJCP.2024.25.3.1077 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Seeta Devi Ruchika Kaul Ghanekar Jayshree Ashok Pande Dipali Dumbre Ranjana Chavan Harshita Gupta Source Type: research

The Relationship between Religious Well-Being, Existential Well-Being, Fear of Progression and Quality of Life in Patients with Cancer: The Mediating Role of Hope
CONCLUSION: A significant positive relationship between hope and quality of life, as well as religious well-being and hope, suggests the influential effects of hope and religious well-being on improving quality of life in patients with cancer. Negative relationships between fear of progression and hope conclude that managing fear of progression may be an important factor in increasing hope and improving quality of life in patients with cancer.PMID:38546091 | DOI:10.31557/APJCP.2024.25.3.1087 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Hamid Sharif Nia Rebecca H Lehto Bahar Farhadi Long She Amir Hossein Goudarzian Fatemeh Khoshnavay Fomani Mobin Mohamadinezhad Source Type: research

Enhancing Women's Quality of Life: Exploring the Impact of Mastectomy with and without Breast Reconstruction among Breast Cancer Survivors in Iraq
CONCLUSION: Contrary to the anticipated benefits of BR, our findings suggest that women who underwent the procedure reported a lower QoL compared to those who did not. The outcomes highlight the discrepancy between expected and actual benefits of BR, suggesting a pressing need for comprehensive rehabilitation programs. These programs should aim to enhance the QoL for post-mastectomy patients and provide in-depth counseling to align expectations with the potential realities of BR.PMID:38546092 | DOI:10.31557/APJCP.2024.25.3.1097 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Bassam Abdul Rasool Hassan Ali Haider Mohammed Abeer Abdulhameed Ahmed Alya A Al Zobair Abdulrasool M Wayyes Haidar Kadhim Al-Jawadi Ahmed Zuhair Abdulhameed Alsammarraie Musaab Kadhim Alabboodi Jin Xin Jiang Source Type: research

From Smoke to Vapor: Understanding the Auditory Consequence from Traditional Smoking to Vaping
Asian Pac J Cancer Prev. 2024 Mar 1;25(3):719-721. doi: 10.31557/APJCP.2024.25.3.719.NO ABSTRACTPMID:38546052 | DOI:10.31557/APJCP.2024.25.3.719 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Rahul Anand Gargi Sarode Namrata Sengupta Sachin Sarode Source Type: research

Cervical Cancer Screening Revolution: Advancements with Confocal Endomicroscopy
Asian Pac J Cancer Prev. 2024 Mar 1;25(3):723-724. doi: 10.31557/APJCP.2024.25.3.723.NO ABSTRACTPMID:38546053 | DOI:10.31557/APJCP.2024.25.3.723 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Bhagyashri Rupesh Patil-Takbhate Source Type: research

A Crosstalk between the Receptor Tyrosine Kinase-Like Orphan Receptors ROR1/2 and S1P Signaling Pathways in Lung Cancer
CONCLUSION: These findings demonstrate the reciprocal regulation of both pathways, suggesting that both pathways have an inverse relation i.e, in the absence of one pathway, another pathway may take charge of the other pathway. Therefore, simultaneously targeting both pathways could serve as a potential therapeutic target for lung cancer treatment.PMID:38546054 | DOI:10.31557/APJCP.2024.25.3.725 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Rajeev Nema Ritu Pandey Ashok Kumar Source Type: research

Optimizing Ideal Thickness of Sections for Epidermis in Intra-Operative Frozen Sections
CONCLUSION: While mucosal margins can be obtained at the usual 5-7 microns, the same thickness is not optimal for skin margins intra-operatively. Frozen sections for the skin margins may be set at 10 microns, to save time, minimize artefacts, and for better readability.PMID:38546055 | DOI:10.31557/APJCP.2024.25.3.735 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Kavya Dharmaraj Deepak Pandiar Reshma Poothakulath Krishnan Source Type: research

Investigation of Plasma Cell-Free DNA and MiRNA in Cholangiocarcinoma and Opisthorchiasis Viverrini Patients
CONCLUSION: Elevated plasma concentrations of cfDNA and cf-miRNA could serve as potential diagnostic tools for distinguishing cholangiocarcinoma from other conditions. cf-miRNA was superior to cfDNA in terms of sensitivity.PMID:38546056 | DOI:10.31557/APJCP.2024.25.3.739 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Sattrachai Prasopdee Montinee Pholhelm Siraphatsorn Yusuk Sithichoke Tangphatsornruang Kritiya Butthongkomvong Anthicha Kunjantarachot Teva Phanaksri Jutharat Kulsantiwong Smarn Tesana Veerachai Thitapakorn Source Type: research

Applications of Quantum Dots in Preventive Oncology
Asian Pac J Cancer Prev. 2024 Mar 1;25(3):747-756. doi: 10.31557/APJCP.2024.25.3.747.ABSTRACTQDs are semiconductor nanocrystalline materials with distinct optical and electronic characteristics due to their microscopic size and quantum mechanical properties. They are often composed of materials such as cadmium selenide (CdSe), cadmium telluride (CdTe), or indium phosphide (InP) and are typically in the size range of 2 to 10 nanometers in diameter. These tiny particles are used in various scientific and technological applications. Some key characteristics and applications of quantum dots are size-dependent Optical Propertie...
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Sajib Sarkar Tryambak Pratap Srivastava Om Saswat Sahoo Abhishek Shankar Avdhesh Rai Karthikeyan Pethusamy Ruby Dhar Subhradip Karmakar Source Type: research

Association of COX-2, TNF- α, TLR4, and IKKα With Survival of Patients With Oral Squamous Cell Carcinomas: A Systematic Review
CONCLUSION: COX-2 overexpression may be associated with a poorer prognosis in oral SCC. The insufficiency of studies about TNF-α, TLR4, and IKKα restrained their validation as predictors of prognosis.PMID:38546058 | DOI:10.31557/APJCP.2024.25.3.757 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Fernando Figueiredo Biasin Andre Medeiros Franco Gabriel Campos Louzeiro Karen Cherubini Fernanda Goncalves Salum Source Type: research

Association of the CXCL12 rs1801157 Polymorphism with Breast Cancer Risk: A Meta-Analysis
Asian Pac J Cancer Prev. 2024 Mar 1;25(3):767-776. doi: 10.31557/APJCP.2024.25.3.767.ABSTRACTStudies on the CXCL12 rs1801157 polymorphism show that this polymorphism is involved in development of breast cancer, but its specific relationships or effects are not consistent. The purpose of this meta-analysis was to investigate the association between CXCL12 rs1801157 polymorphism and susceptibility to breast cancer. PubMed, Scopus, Embase, the Cochrane Library, Web of Science, and CNKI were searched for eligible studies through February 01, 2023. A total of ten studies with 2093 cases and 2302 controls were included in this m...
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Abolhasan Alijanpour Ahmadreza Golshan Mohammad Vakili-Ojarood Ahmad Shirinzadeh-Dastgiri Amirhosein Naseri Mojgan Karimi-Zarchi Nazanin Hajizadeh Maedeh Barahman Sepideh Azizi Maryam Aghasipour Sahel Khajehnoori Kazem Aghili Hossein Neamatzadeh Source Type: research