Experimental and Therapeutic Medicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

An asymptomatic male individual carrying a 5.72 Mb de novo deletion in 8p23.2 ‑p23.3: A case report
Exp Ther Med. 2024 Apr 3;27(6):241. doi: 10.3892/etm.2024.12529. eCollection 2024 Jun.ABSTRACTNumerous rearrangements in the 8p23 chromosomal region have been reported; included in these rearrangements are isolated deletions in this area. Such deletions are associated with a wide range of phenotypic characteristics, including motor impairment, epilepsy, intellectual disability, cardiac defects and seizures. The present study describes the case of a 30-year-old asymptomatic man that carries a de novo deletion in 8p23.2-p23.3. Molecular karyotyping indicated that the detected deletion involves genes that are in the critical ...
Source: Experimental and Therapeutic Medicine - April 25, 2024 Category: General Medicine Authors: Christina Keramida Ioannis Papoulidis Efterpi Pappa Thomas Liehr Konstantinos Kalmantis Angeliki Gerede Efterpi Pavlidou Michael Bjorn Petersen Emmanouil Manolakos Source Type: research

Erratum: [Corrigendum] Downregulated caveolin ‑1 expression serves a potential role in coronary artery spasm by inducing nitric oxide production in vitro 
Exp Ther Med. 2024 Apr 10;27(6):247. doi: 10.3892/etm.2024.12535. eCollection 2024 Jun.ABSTRACT[This corrects the article DOI: 10.3892/etm.2018.6646.].PMID:38660522 | PMC:PMC11040280 | DOI:10.3892/etm.2024.12535 (Source: Experimental and Therapeutic Medicine)
Source: Experimental and Therapeutic Medicine - April 25, 2024 Category: General Medicine Authors: Xingmei Cao Zhishuai Ye Mingyu Jin Shuai Yan Xiantao Song Rongchong Huang Source Type: research

Evaluation of the efficacy of silymarin and dexmedetomidine on kidney and lung tissue in the treatment of sepsis in rats with cecal perforation
Exp Ther Med. 2024 Apr 3;27(6):242. doi: 10.3892/etm.2024.12530. eCollection 2024 Jun.ABSTRACTSepsis is a systemic inflammatory response syndrome that develops in the host against microorganisms. This response develops away from the primary infection site and results in end-organ damage. The present study aimed to investigate the protective and therapeutic effects on lung and kidney tissue of silymarin (S) and dexmedetomidine (DEX) applied 1 h before and after sepsis induced by the cecal ligation and puncture (CLP) method in rats. A total of 62 rats was randomly divided into eight groups: i) Control (n=6); ii) cecal perfor...
Source: Experimental and Therapeutic Medicine - April 24, 2024 Category: General Medicine Authors: Aydin Yavuz Ay şegül Küçük Aydan İremnur Ergörün Ali Do ğan Dursun Zeynep Yi ğman Metin Alkan Mustafa Arslan Source Type: research

Acute myocardial infarction due to spontaneous coronary artery dissection in a young male with systemic lupus erythematosus: A case report
Exp Ther Med. 2024 Apr 9;27(6):246. doi: 10.3892/etm.2024.12534. eCollection 2024 Jun.ABSTRACTSystemic lupus erythematosus (SLE) is an autoimmune disease which typically presents in young women. Patients with SLE exhibit features of accelerated atherosclerosis. Here, the present study reported a rare case of acute myocardial infarction (AMI) in a male patient diagnosed with SLE. A 29-year-old male with no cardiovascular history was diagnosed with AMI and underwent coronary angiography, which showed a long-extended spiral-shaped dissection of the right coronary artery (RCA). The patient's autoimmune panel tested positive fo...
Source: Experimental and Therapeutic Medicine - April 24, 2024 Category: General Medicine Authors: Yunyi Li Quan Zhou Xiao Meng Source Type: research

Erratum: [Corrigendum] Macleaya cordata extracts exert antiviral effects in newborn mice with rotavirus ‑induced diarrhea via inhibiting the JAK2/STAT3 signaling pathway
Exp Ther Med. 2024 Apr 4;27(6):243. doi: 10.3892/etm.2024.12531. eCollection 2024 Jun.ABSTRACT[This corrects the article DOI: 10.3892/etm.2020.8766.].PMID:38655038 | PMC:PMC11036352 | DOI:10.3892/etm.2024.12531 (Source: Experimental and Therapeutic Medicine)
Source: Experimental and Therapeutic Medicine - April 24, 2024 Category: General Medicine Authors: Chunmao Jiang Haifeng Yang Xiaolan Chen Shulei Qiu Caihong Wu Bin Zhang Liqin Jin Source Type: research

An observational study of symmetrical VSD occluder for transcatheter closure of ruptured sinus of Valsalva aneurysm
In conclusion, the TCC of RSVA with the China made symmetrical VSD occluder is safe and effective.PMID:38655039 | PMC:PMC11036356 | DOI:10.3892/etm.2024.12532 (Source: Experimental and Therapeutic Medicine)
Source: Experimental and Therapeutic Medicine - April 24, 2024 Category: General Medicine Authors: Wei Chen Tongbin Li Xiaolin Lei Haitao Liu Source Type: research

[Retracted] MicroRNA ‑338‑3p suppresses cell proliferation, migration and invasion in human malignant melanoma by targeting MACC1
Exp Ther Med. 2024 Apr 8;27(6):245. doi: 10.3892/etm.2024.12533. eCollection 2024 Jun.ABSTRACT[This retracts the article DOI: 10.3892/etm.2019.7644.].PMID:38655040 | PMC:PMC11036350 | DOI:10.3892/etm.2024.12533 (Source: Experimental and Therapeutic Medicine)
Source: Experimental and Therapeutic Medicine - April 24, 2024 Category: General Medicine Authors: Chunhua Zhang Hui Li Junling Wang Jibei Zhang Xiaoqian Hou Source Type: research

Effect of 23 ‑hydroxybetulinic acid on lung adenocarcinoma and its mechanism of action
In conclusion, Pulsatilla compounds were indicated to inhibit the viability and proliferation of lung adenocarcinoma H1299 cells, and the mechanism of action was related to PPAR-γ, the PPAR signaling pathway and mitochondrial ROS. The present study provides novel insight to further explore the treatment of lung adenocarcinoma.PMID:38633355 | PMC:PMC11019653 | DOI:10.3892/etm.2024.12527 (Source: Experimental and Therapeutic Medicine)
Source: Experimental and Therapeutic Medicine - April 18, 2024 Category: General Medicine Authors: Boyu Tan Xiaoxu Lan Yifan Zhang Pai Liu Qiyao Jin Zhiqiang Wang Zhidong Liang Wei Song Ye Xuan Yunxiao Sun Youjie Li Source Type: research

[Retracted] The AMPK ‑mTOR axis requires increased MALAT1 expression for promoting granulosa cell proliferation in endometriosis
Exp Ther Med. 2024 Apr 2;27(6):240. doi: 10.3892/etm.2024.12528. eCollection 2024 Jun.ABSTRACT[This retracts the article DOI: 10.3892/etm.2020.9453.].PMID:38633356 | PMC:PMC11019655 | DOI:10.3892/etm.2024.12528 (Source: Experimental and Therapeutic Medicine)
Source: Experimental and Therapeutic Medicine - April 18, 2024 Category: General Medicine Authors: Xuejie Liu Ping Zhang Yanmin Li Na Zhao Haiyan Han Source Type: research