Effect of 23 ‑hydroxybetulinic acid on lung adenocarcinoma and its mechanism of action

In conclusion, Pulsatilla compounds were indicated to inhibit the viability and proliferation of lung adenocarcinoma H1299 cells, and the mechanism of action was related to PPAR-γ, the PPAR signaling pathway and mitochondrial ROS. The present study provides novel insight to further explore the treatment of lung adenocarcinoma.PMID:38633355 | PMC:PMC11019653 | DOI:10.3892/etm.2024.12527

Source: Experimental and Therapeutic Medicine - April 18, 2024 Category: General Medicine Authors: Boyu Tan Xiaoxu Lan Yifan Zhang Pai Liu Qiyao Jin Zhiqiang Wang Zhidong Liang Wei Song Ye Xuan Yunxiao Sun Youjie Li Source Type: research