Personalized digital simulation ‑assisted acetabular component implantation in revision hip arthroplasty
Exp Ther Med. 2024 Mar 4;27(5):180. doi: 10.3892/etm.2024.12468. eCollection 2024 May.ABSTRACTThe number of artificial total hip revision arthroplasties is increasing yearly in China, and >50% of these cases have acetabular defects. Accurately locating and quantifying the bone defect is one of the current challenges of this surgery. Thus, the objective of the present study was to simulate acetabular implantation with the aid of Mimics 17.0 software (Materialise NV) in patients with loosened acetabular prosthesis, to evaluate the 'ideal acetabular center' and the 'actual acetabular center' to guide the choice of prosthes...
Source: Experimental and Therapeutic Medicine - March 22, 2024 Category: General Medicine Authors: Hong-Da Lao Da Liu Bin Cheng Shu-Ling Liu Feng Shuang Hao Li Lei Li Jiang-Jun Zhou Source Type: research

Mesenchymal stem cells derived from CHIR99021 and TGF ‑β induction remained on the colicomentum and improved cardiac function of a rat model of acute myocardium infarction
In conclusion, the CHIR99021 and TGF-β combined induction was a rapid and effective method to obtain MSC-like cells from hiPSCs and multiple high dose intraperitoneal injections of hiPSC-derived MSCs were safe and effective at restoring cardiac function in an AMI rat model.PMID:38515646 | PMC:PMC10952379 | DOI:10.3892/etm.2024.12470 (Source: Experimental and Therapeutic Medicine)
Source: Experimental and Therapeutic Medicine - March 22, 2024 Category: General Medicine Authors: Yusen Zhang Yanmin Zhang Azhen Hu Fanhua Meng Peng Cui Tianshi Li Guanghui Cui Source Type: research

Early postnatal moderate catch ‑up growth in rats with nutritional intrauterine growth restriction preserves pulmonary vascular and cognitive function in adulthood
Exp Ther Med. 2024 Mar 5;27(5):183. doi: 10.3892/etm.2024.12471. eCollection 2024 May.ABSTRACTIntrauterine growth restriction (IUGR) with rapid postnatal catch-up growth is strongly associated with pulmonary vascular dysfunction in adulthood, whereas IUGR with delayed growth in early postnatal life results in long-term brain deficits. In the present study, it was hypothesized that IUGR with early moderate catch-up growth may alleviate pulmonary vascular remodeling in adulthood without affecting memory function. An IUGR model was established by restricting maternal nutrition during pregnancy. Different growth patterns were ...
Source: Experimental and Therapeutic Medicine - March 22, 2024 Category: General Medicine Authors: Lixia Ye Yajie Huang Kewei Chen Chengcheng Hang Yuhan Ying Lu Zu Xiaofei Luo Lizhong Du Source Type: research

Timely use of Bakri intrauterine balloon tamponade contributes to the effectiveness in controlling severe postpartum hemorrhage
In conclusion, placenta accrete may be the leading cause of SPPH. Bakri IUBT is an effective and safe measure for SPPH. Pre-IUBT intervention may be predictive of Bakri's success. The timely use of IUBT during labor may mitigate the impact of risk factors identified on PPH.PMID:38515648 | PMC:PMC10952343 | DOI:10.3892/etm.2024.12465 (Source: Experimental and Therapeutic Medicine)
Source: Experimental and Therapeutic Medicine - March 22, 2024 Category: General Medicine Authors: Yaping Hu Lingjie Cui Chong Zhang Feifei Chen Source Type: research

[Retracted] MicroRNA ‑454‑3p inhibits cervical cancer cell invasion and migration by targeting c‑Met
Exp Ther Med. 2024 Mar 4;27(5):179. doi: 10.3892/etm.2024.12467. eCollection 2024 May.ABSTRACT[This retracts the article DOI: 10.3892/etm.2018.5714.].PMID:38515649 | PMC:PMC10952372 | DOI:10.3892/etm.2024.12467 (Source: Experimental and Therapeutic Medicine)
Source: Experimental and Therapeutic Medicine - March 22, 2024 Category: General Medicine Authors: Yan Guo Min Tao Min Jiang Source Type: research

Impact of preoperative carbohydrate loading on postoperative course and morbidity in debulking surgery for epithelial ovarian cancer
In conclusion, based on the results of the present study, postoperative course and morbidity seemed to be unaffected by carbohydrate loading in patients undergoing debulking surgery for EOC.PMID:38515650 | PMC:PMC10952341 | DOI:10.3892/etm.2024.12469 (Source: Experimental and Therapeutic Medicine)
Source: Experimental and Therapeutic Medicine - March 22, 2024 Category: General Medicine Authors: Tayfun Toptas Isin Ureyen Alper Kahraman Mustafa Gokkaya Necim Yalcin Aysun Alci Merve Cakir Kole Selim Kandemi R Mehmet Goksu Nedim Akgul Selen Dogan Source Type: research

Anlotinib plus tislelizumab for recurrent metastatic pancreas ductal adenocarcinoma with germline BRCA2 mutation: A case report
In conclusion, the combination of tislelizumab and anlotinib may offer a viable therapeutic option for recurrent metastatic BRCA2-mutated PDAC.PMID:38515651 | PMC:PMC10952340 | DOI:10.3892/etm.2024.12466 (Source: Experimental and Therapeutic Medicine)
Source: Experimental and Therapeutic Medicine - March 22, 2024 Category: General Medicine Authors: Sujuan Peng Hongxiang Huang Xie Zhu Jinhong Chen Xinjing Ding Fen Wang Li Chen Zhihui Lu Source Type: research

Personalized digital simulation ‑assisted acetabular component implantation in revision hip arthroplasty
Exp Ther Med. 2024 Mar 4;27(5):180. doi: 10.3892/etm.2024.12468. eCollection 2024 May.ABSTRACTThe number of artificial total hip revision arthroplasties is increasing yearly in China, and >50% of these cases have acetabular defects. Accurately locating and quantifying the bone defect is one of the current challenges of this surgery. Thus, the objective of the present study was to simulate acetabular implantation with the aid of Mimics 17.0 software (Materialise NV) in patients with loosened acetabular prosthesis, to evaluate the 'ideal acetabular center' and the 'actual acetabular center' to guide the choice of prosthes...
Source: Experimental and Therapeutic Medicine - March 22, 2024 Category: General Medicine Authors: Hong-Da Lao Da Liu Bin Cheng Shu-Ling Liu Feng Shuang Hao Li Lei Li Jiang-Jun Zhou Source Type: research

Mesenchymal stem cells derived from CHIR99021 and TGF ‑β induction remained on the colicomentum and improved cardiac function of a rat model of acute myocardium infarction
In conclusion, the CHIR99021 and TGF-β combined induction was a rapid and effective method to obtain MSC-like cells from hiPSCs and multiple high dose intraperitoneal injections of hiPSC-derived MSCs were safe and effective at restoring cardiac function in an AMI rat model.PMID:38515646 | PMC:PMC10952379 | DOI:10.3892/etm.2024.12470 (Source: Experimental and Therapeutic Medicine)
Source: Experimental and Therapeutic Medicine - March 22, 2024 Category: General Medicine Authors: Yusen Zhang Yanmin Zhang Azhen Hu Fanhua Meng Peng Cui Tianshi Li Guanghui Cui Source Type: research

Early postnatal moderate catch ‑up growth in rats with nutritional intrauterine growth restriction preserves pulmonary vascular and cognitive function in adulthood
Exp Ther Med. 2024 Mar 5;27(5):183. doi: 10.3892/etm.2024.12471. eCollection 2024 May.ABSTRACTIntrauterine growth restriction (IUGR) with rapid postnatal catch-up growth is strongly associated with pulmonary vascular dysfunction in adulthood, whereas IUGR with delayed growth in early postnatal life results in long-term brain deficits. In the present study, it was hypothesized that IUGR with early moderate catch-up growth may alleviate pulmonary vascular remodeling in adulthood without affecting memory function. An IUGR model was established by restricting maternal nutrition during pregnancy. Different growth patterns were ...
Source: Experimental and Therapeutic Medicine - March 22, 2024 Category: General Medicine Authors: Lixia Ye Yajie Huang Kewei Chen Chengcheng Hang Yuhan Ying Lu Zu Xiaofei Luo Lizhong Du Source Type: research

Timely use of Bakri intrauterine balloon tamponade contributes to the effectiveness in controlling severe postpartum hemorrhage
In conclusion, placenta accrete may be the leading cause of SPPH. Bakri IUBT is an effective and safe measure for SPPH. Pre-IUBT intervention may be predictive of Bakri's success. The timely use of IUBT during labor may mitigate the impact of risk factors identified on PPH.PMID:38515648 | PMC:PMC10952343 | DOI:10.3892/etm.2024.12465 (Source: Experimental and Therapeutic Medicine)
Source: Experimental and Therapeutic Medicine - March 22, 2024 Category: General Medicine Authors: Yaping Hu Lingjie Cui Chong Zhang Feifei Chen Source Type: research

[Retracted] MicroRNA ‑454‑3p inhibits cervical cancer cell invasion and migration by targeting c‑Met
Exp Ther Med. 2024 Mar 4;27(5):179. doi: 10.3892/etm.2024.12467. eCollection 2024 May.ABSTRACT[This retracts the article DOI: 10.3892/etm.2018.5714.].PMID:38515649 | PMC:PMC10952372 | DOI:10.3892/etm.2024.12467 (Source: Experimental and Therapeutic Medicine)
Source: Experimental and Therapeutic Medicine - March 22, 2024 Category: General Medicine Authors: Yan Guo Min Tao Min Jiang Source Type: research

Impact of preoperative carbohydrate loading on postoperative course and morbidity in debulking surgery for epithelial ovarian cancer
In conclusion, based on the results of the present study, postoperative course and morbidity seemed to be unaffected by carbohydrate loading in patients undergoing debulking surgery for EOC.PMID:38515650 | PMC:PMC10952341 | DOI:10.3892/etm.2024.12469 (Source: Experimental and Therapeutic Medicine)
Source: Experimental and Therapeutic Medicine - March 22, 2024 Category: General Medicine Authors: Tayfun Toptas Isin Ureyen Alper Kahraman Mustafa Gokkaya Necim Yalcin Aysun Alci Merve Cakir Kole Selim Kandemi R Mehmet Goksu Nedim Akgul Selen Dogan Source Type: research

Anlotinib plus tislelizumab for recurrent metastatic pancreas ductal adenocarcinoma with germline BRCA2 mutation: A case report
In conclusion, the combination of tislelizumab and anlotinib may offer a viable therapeutic option for recurrent metastatic BRCA2-mutated PDAC.PMID:38515651 | PMC:PMC10952340 | DOI:10.3892/etm.2024.12466 (Source: Experimental and Therapeutic Medicine)
Source: Experimental and Therapeutic Medicine - March 22, 2024 Category: General Medicine Authors: Sujuan Peng Hongxiang Huang Xie Zhu Jinhong Chen Xinjing Ding Fen Wang Li Chen Zhihui Lu Source Type: research

Personalized digital simulation ‑assisted acetabular component implantation in revision hip arthroplasty
Exp Ther Med. 2024 Mar 4;27(5):180. doi: 10.3892/etm.2024.12468. eCollection 2024 May.ABSTRACTThe number of artificial total hip revision arthroplasties is increasing yearly in China, and >50% of these cases have acetabular defects. Accurately locating and quantifying the bone defect is one of the current challenges of this surgery. Thus, the objective of the present study was to simulate acetabular implantation with the aid of Mimics 17.0 software (Materialise NV) in patients with loosened acetabular prosthesis, to evaluate the 'ideal acetabular center' and the 'actual acetabular center' to guide the choice of prosthes...
Source: Experimental and Therapeutic Medicine - March 22, 2024 Category: General Medicine Authors: Hong-Da Lao Da Liu Bin Cheng Shu-Ling Liu Feng Shuang Hao Li Lei Li Jiang-Jun Zhou Source Type: research