A Novel Oncogenic RET Fusion Variant in NSCLC: RELCH-RET
J Thorac Oncol. 2021 Oct;16(10):e95. doi: 10.1016/j.jtho.2020.12.018.NO ABSTRACTPMID:34561049 | DOI:10.1016/j.jtho.2020.12.018 (Source: Ann Oncol)
Source: Ann Oncol - September 25, 2021 Category: Cancer & Oncology Authors: Scott P Myrand Source Type: research

ASO Author Reflections: Positive Sentinel Lymph Node in Breast Cancer Surgery
Ann Surg Oncol. 2021 Sep 24. doi: 10.1245/s10434-021-10836-y. Online ahead of print.NO ABSTRACTPMID:34561776 | DOI:10.1245/s10434-021-10836-y (Source: Ann Oncol)
Source: Ann Oncol - September 25, 2021 Category: Cancer & Oncology Authors: Eduardo Camargo Millen Francisco Pimentel Cavalcante Source Type: research

ASO Author Reflections: Adjuvant Therapy for Stage III Melanoma With or Without Completion Lymph Node Dissection
Ann Surg Oncol. 2021 Sep 24. doi: 10.1245/s10434-021-10838-w. Online ahead of print.NO ABSTRACTPMID:34561777 | DOI:10.1245/s10434-021-10838-w (Source: Ann Oncol)
Source: Ann Oncol - September 25, 2021 Category: Cancer & Oncology Authors: Robert J Torphy Martin D McCarter Ana L Gleisner Source Type: research

Invited Editorial: Does Side Really Matter? Survival Analysis Among Patients with Right- Versus Left-Sided Colon Cancer: A Propensity Score-Adjusted Analysis
Ann Surg Oncol. 2021 Sep 24. doi: 10.1245/s10434-020-09522-2. Online ahead of print.NO ABSTRACTPMID:34561778 | DOI:10.1245/s10434-020-09522-2 (Source: Ann Oncol)
Source: Ann Oncol - September 25, 2021 Category: Cancer & Oncology Authors: Austin J Livingston Christina E Bailey Source Type: research

Correction to: Patient-Reported Outcomes of Video-Assisted Thoracoscopic Surgery Versus Thoracotomy for Locally Advanced Lung Cancer: A Longitudinal Cohort Study
Ann Surg Oncol. 2021 Sep 24. doi: 10.1245/s10434-021-10798-1. Online ahead of print.NO ABSTRACTPMID:34561779 | DOI:10.1245/s10434-021-10798-1 (Source: Ann Oncol)
Source: Ann Oncol - September 25, 2021 Category: Cancer & Oncology Authors: Xing Wei Hongfan Yu Wei Dai Yunfei Mu Yaqin Wang Jia Liao Lin Peng Yongtao Han Qiang Li Qiuling Shi Source Type: research

Consolidation nivolumab and ipilimumab versus observation in limited-disease small cell lung cancer after chemo-radiotherapy - Results from the randomised phase II ETOP/IFCT 4-12 STIMULI trial
CONCLUSIONS: The STIMULI trial did not meet its primary endpoint of improving PFS with nivolumab-ipilimumab consolidation after chemo-radiotherapy in LD-SCLC. A short period on active treatment related to toxicity and treatment discontinuation likely affected the efficacy results.PMID:34562610 | DOI:10.1016/j.annonc.2021.09.011 (Source: Ann Oncol)
Source: Ann Oncol - September 25, 2021 Category: Cancer & Oncology Authors: S Peters J-L Pujol U Dafni M D ómine S Popat M Reck J Andrade A Becker D Moro-Sibilot A Curioni-Fontecedro O Molinier K Nackaerts A Insa Moll á R Gervais G L ópez Vivanco J Madelaine J Mazieres M Faehling F Griesinger M Majem J L Gonz ález Larriba M P Source Type: research

Harmful cytokines in cancer immunology and immunotherapy: biomarkers and targets?
Ann Oncol. 2021 Sep 21:S0923-7534(21)04489-6. doi: 10.1016/j.annonc.2021.09.010. Online ahead of print.NO ABSTRACTPMID:34560240 | DOI:10.1016/j.annonc.2021.09.010 (Source: Ann Oncol)
Source: Ann Oncol - September 24, 2021 Category: Cancer & Oncology Authors: Ignacio Melero Nicola Normanno Source Type: research

The ESMO-EURACAN-GENTURIS-ERNPaedCan Clinical Practice Guidelines for bone sarcomas - the challenges of the fight against rare cancers
Ann Oncol. 2021 Sep 21:S0923-7534(21)04492-6. doi: 10.1016/j.annonc.2021.09.013. Online ahead of print.NO ABSTRACTPMID:34560241 | DOI:10.1016/j.annonc.2021.09.013 (Source: Ann Oncol)
Source: Ann Oncol - September 24, 2021 Category: Cancer & Oncology Authors: D Andreou Source Type: research

Gastrointestinal stromal tumours: ESMO-EURACAN-GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up
Ann Oncol. 2021 Sep 14:S0923-7534(21)04480-X. doi: 10.1016/j.annonc.2021.09.005. Online ahead of print.NO ABSTRACTPMID:34560242 | DOI:10.1016/j.annonc.2021.09.005 (Source: Ann Oncol)
Source: Ann Oncol - September 24, 2021 Category: Cancer & Oncology Authors: P G Casali J Y Blay N Abecassis J Bajpai S Bauer R Biagini S Bielack S Bonvalot I Boukovinas J V M G Bovee K Boye T Brodowicz A Buonadonna E De Álava A P Dei Tos X G Del Muro A Dufresne M Eriksson A Fedenko V Ferraresi A Ferrari A M Frezza S Gasperoni H Source Type: research

ASO Visual Abstract: Development of a Prognostic Nomogram and Nomogram Software Application Tool to Predict Overall Survival and Disease-Free Survival After Curative-Intent Gastrectomy for Gastric Cancer
Ann Surg Oncol. 2021 Sep 22. doi: 10.1245/s10434-021-10853-x. Online ahead of print.NO ABSTRACTPMID:34553302 | DOI:10.1245/s10434-021-10853-x (Source: Ann Oncol)
Source: Ann Oncol - September 23, 2021 Category: Cancer & Oncology Authors: Gaya Spolverato Giulia Capelli Giulia Lorenzoni Dario Gregori Malcolm H Squires George A Poultsides Ryan C Fields Mark P Bloomston Sharon M Weber Konstantinos I Votanopoulos Alexandra W Acher Linda X Jin William G Hawkins Carl R Schmidt David A Kooby Davi Source Type: research

ASO Author Reflections: Imaging Predictors of High-Grade Dysplasia or Malignancy in Branch Duct Type Intraductal Papillary Mucinous Neoplasms of the Pancreas: A Systematic Review and Meta-Analysis
Ann Surg Oncol. 2021 Sep 22. doi: 10.1245/s10434-021-10746-z. Online ahead of print.NO ABSTRACTPMID:34553303 | DOI:10.1245/s10434-021-10746-z (Source: Ann Oncol)
Source: Ann Oncol - September 23, 2021 Category: Cancer & Oncology Authors: Wenjing Zhao Yupei Zhao Source Type: research

Prognosis Associated With Luminal and Basal Subtypes of Metastatic Prostate Cancer
JAMA Oncol. 2021 Sep 23. doi: 10.1001/jamaoncol.2021.3987. Online ahead of print.ABSTRACTIMPORTANCE: Luminal and basal subtypes of primary prostate cancer have been shown to be molecularly distinct and clinically important in predicting response to therapy. These subtypes have not been described in metastatic prostate cancer.OBJECTIVES: To identify clinical and molecular correlates of luminal and basal subtypes in metastatic castration-resistant prostate cancer (mCRPC) and investigate differences in survival, particularly after treatment with androgen-signaling inhibitors (ASIs).DESIGN, SETTING, AND PARTICIPANTS: In this c...
Source: Ann Oncol - September 23, 2021 Category: Cancer & Oncology Authors: Rahul Aggarwal Nicholas R Rydzewski Li Zhang Adam Foye Won Kim Kyle T Helzer Hamza Bakhtiar S Laura Chang Marc D Perry Martin Gleave Robert E Reiter Jiaoti Huang Christopher P Evans Joshi J Alumkal Joshua M Lang Menggang Yu David A Quigley Martin Sj östr Source Type: research

Atypical Lobular Hyperplasia and Classic Lobular Carcinoma In Situ Can Be Safely Managed Without Surgical Excision
CONCLUSION: Non-surgical management of pure LN is safe, and the likelihood of requiring subsequent surgical excision or repeat CNB during follow-up is low. These data provide reassurance that routine excision of pure LN in the setting of radiologic-pathologic concordance is not required.PMID:34554341 | DOI:10.1245/s10434-021-10827-z (Source: Ann Oncol)
Source: Ann Oncol - September 23, 2021 Category: Cancer & Oncology Authors: Alison Laws Fisher Katlin Faina Nakhlis Sona A Chikarmane Stuart J Schnitt Tari A King Source Type: research

Incremental Spending Associated with Low-Value Treatments in Older Women with Breast Cancer
Ann Surg Oncol. 2021 Sep 23. doi: 10.1245/s10434-021-10807-3. Online ahead of print.ABSTRACTBACKGROUND: In most women ≥ 70 years old with hormone-receptor-positive breast cancer, axillary staging and adjuvant radiotherapy provide no survival advantage over surgery and hormone therapy alone. Despite recommendations for their omission, sentinel lymph node biopsy (SLNB) and adjuvant radiotherapy rates remain high. While treatment side effects are well documented, less is known about the incremental spending associated with SLNB and adjuvant radiotherapy.METHODS: Using a statewide multipayer claims registry, we examined spe...
Source: Ann Oncol - September 23, 2021 Category: Cancer & Oncology Authors: Brooke C Bredbeck Alison S Baskin Ton Wang Brandy R Sinco Nicholas L Berlin Sarah P Shubeck Nicole M Mott Rachel A Greenup Hari Nathan Tasha M Hughes Lesly A Dossett Source Type: research

Imaging Features for Predicting High-Grade Dysplasia or Malignancy in Branch Duct Type Intraductal Papillary Mucinous Neoplasm of the Pancreas: A Systematic Review and Meta-Analysis
CONCLUSIONS: The aforementioned imaging features could aid in predicting HGD/malignancy of BD-IPMN. Furthermore, enhanced solid component/MN and an MPD diameter of 10 mm or greater were the most important predictors of HGD/malignancy in BD-IPMN and should be considered as indications for surgery.PMID:34554343 | DOI:10.1245/s10434-021-10662-2 (Source: Ann Oncol)
Source: Ann Oncol - September 23, 2021 Category: Cancer & Oncology Authors: Wenjing Zhao Shanglong Liu Lin Cong Yupei Zhao Source Type: research

Reply to T. Shimoi et al and Y. Shimanuki et al
J Clin Oncol. 2021 Sep 23:JCO2101905. doi: 10.1200/JCO.21.01905. Online ahead of print.NO ABSTRACTPMID:34554848 | DOI:10.1200/JCO.21.01905 (Source: Ann Oncol)
Source: Ann Oncol - September 23, 2021 Category: Cancer & Oncology Authors: Ingrid A Mayer Fengmin Zhao Carlos L Arteaga William F Symmans Ben H Park Brian L Burnette Amye J Tevaarwerk Sofia F Garcia Karen L Smith Della F Makower Margaret Block Kimberly A Morley Chirag R Jani Craig Mescher Shabana J Dewani Bernard Tawfik Lisa E F Source Type: research

Toxicity Index, Patient-Reported Outcomes, and Early Discontinuation of Endocrine Therapy for Breast Cancer Risk Reduction in NRG Oncology/NSABP B-35
J Clin Oncol. 2021 Sep 23:JCO2100910. doi: 10.1200/JCO.21.00910. Online ahead of print.ABSTRACT[Figure: see text].PMID:34554865 | DOI:10.1200/JCO.21.00910 (Source: Ann Oncol)
Source: Ann Oncol - September 23, 2021 Category: Cancer & Oncology Authors: N Lynn Henry Sungjin Kim Ron D Hays Marcio A Diniz Michael Luu Reena S Cecchini Greg Yothers Andr é Rogatko Patricia A Ganz Source Type: research

Impact of the methylation classifier and ancillary methods on CNS tumor diagnostics
CONCLUSIONS: This work assesses the impact of a methylation classifier and additional methods in a consultative practice by defining the proportions with concordant vs. change in diagnosis in a set of diagnostically challenging CNS tumors. We address approaches to low-confidence scores and confounding issues of low tumor purity.PMID:34555175 | DOI:10.1093/neuonc/noab227 (Source: Ann Oncol)
Source: Ann Oncol - September 23, 2021 Category: Cancer & Oncology Authors: Zhichao Wu Zied Abdullaev Drew Pratt Hye-Jung Chung Shannon Skarshaug Valerie Zgonc Candice Perry Svetlana Pack Lola Saidkhodjaeva Sushma Nagaraj Manoj Tyagi Vineela Gangalapudi Kristin Valdez Rust Turakulov Liqiang Xi Mark Raffeld Antonios Papanicolau-Se Source Type: research

Hesitancy around low dose CT screening for lung cancer
Ann Oncol. 2021 Sep 20:S0923-7534(21)04487-2. doi: 10.1016/j.annonc.2021.09.008. Online ahead of print.ABSTRACTLung cancer is the leading cause of cancer death worldwide. The absence of symptoms in early stage (I/II) disease, when curative treatment is possible, results in greater than 70% of cases being diagnosed at late stage (III/IV), when treatment is rarely curative. This contributes greatly to lung cancer's poor prognosis which sees only 16.2% of individuals diagnosed with the disease alive at 5 years. Early detection is key to improving lung cancer survival outcomes. As a result, there has been longstanding interest...
Source: Ann Oncol - September 23, 2021 Category: Cancer & Oncology Authors: J L Dickson C Horst A Nair S Tisi R Prendecki S M Janes Source Type: research

Effects of active cancer treatment on safety and immunogenicity of COVID-19 mRNA-BNT162b2 vaccine: Preliminary results from the prospective observational Vax-On study
Ann Oncol. 2021 Sep 20:S0923-7534(21)04488-4. doi: 10.1016/j.annonc.2021.09.009. Online ahead of print.NO ABSTRACTPMID:34555502 | PMC:PMC8452134 | DOI:10.1016/j.annonc.2021.09.009 (Source: Ann Oncol)
Source: Ann Oncol - September 23, 2021 Category: Cancer & Oncology Authors: F Nelli A Fabbri A Onorato D Giannarelli M A Silvestri J R Giron Berrios A Virtuoso E Marrucci C Signorelli M G Chilelli F Primi M Schirripa M Mazzotta E M Ruggeri Source Type: research

ASO Visual Abstract: Development of a Prognostic Nomogram and Nomogram Software Application Tool to Predict Overall Survival and Disease-Free Survival After Curative-Intent Gastrectomy for Gastric Cancer
Ann Surg Oncol. 2021 Sep 22. doi: 10.1245/s10434-021-10853-x. Online ahead of print.NO ABSTRACTPMID:34553302 | DOI:10.1245/s10434-021-10853-x (Source: Ann Oncol)
Source: Ann Oncol - September 23, 2021 Category: Cancer & Oncology Authors: Gaya Spolverato Giulia Capelli Giulia Lorenzoni Dario Gregori Malcolm H Squires George A Poultsides Ryan C Fields Mark P Bloomston Sharon M Weber Konstantinos I Votanopoulos Alexandra W Acher Linda X Jin William G Hawkins Carl R Schmidt David A Kooby Davi Source Type: research

ASO Author Reflections: Imaging Predictors of High-Grade Dysplasia or Malignancy in Branch Duct Type Intraductal Papillary Mucinous Neoplasms of the Pancreas: A Systematic Review and Meta-Analysis
Ann Surg Oncol. 2021 Sep 22. doi: 10.1245/s10434-021-10746-z. Online ahead of print.NO ABSTRACTPMID:34553303 | DOI:10.1245/s10434-021-10746-z (Source: Ann Oncol)
Source: Ann Oncol - September 23, 2021 Category: Cancer & Oncology Authors: Wenjing Zhao Yupei Zhao Source Type: research

Prognosis Associated With Luminal and Basal Subtypes of Metastatic Prostate Cancer
JAMA Oncol. 2021 Sep 23. doi: 10.1001/jamaoncol.2021.3987. Online ahead of print.ABSTRACTIMPORTANCE: Luminal and basal subtypes of primary prostate cancer have been shown to be molecularly distinct and clinically important in predicting response to therapy. These subtypes have not been described in metastatic prostate cancer.OBJECTIVES: To identify clinical and molecular correlates of luminal and basal subtypes in metastatic castration-resistant prostate cancer (mCRPC) and investigate differences in survival, particularly after treatment with androgen-signaling inhibitors (ASIs).DESIGN, SETTING, AND PARTICIPANTS: In this c...
Source: Ann Oncol - September 23, 2021 Category: Cancer & Oncology Authors: Rahul Aggarwal Nicholas R Rydzewski Li Zhang Adam Foye Won Kim Kyle T Helzer Hamza Bakhtiar S Laura Chang Marc D Perry Martin Gleave Robert E Reiter Jiaoti Huang Christopher P Evans Joshi J Alumkal Joshua M Lang Menggang Yu David A Quigley Martin Sj östr Source Type: research

Atypical Lobular Hyperplasia and Classic Lobular Carcinoma In Situ Can Be Safely Managed Without Surgical Excision
CONCLUSION: Non-surgical management of pure LN is safe, and the likelihood of requiring subsequent surgical excision or repeat CNB during follow-up is low. These data provide reassurance that routine excision of pure LN in the setting of radiologic-pathologic concordance is not required.PMID:34554341 | DOI:10.1245/s10434-021-10827-z (Source: Ann Oncol)
Source: Ann Oncol - September 23, 2021 Category: Cancer & Oncology Authors: Alison Laws Fisher Katlin Faina Nakhlis Sona A Chikarmane Stuart J Schnitt Tari A King Source Type: research

Incremental Spending Associated with Low-Value Treatments in Older Women with Breast Cancer
Ann Surg Oncol. 2021 Sep 23. doi: 10.1245/s10434-021-10807-3. Online ahead of print.ABSTRACTBACKGROUND: In most women ≥ 70 years old with hormone-receptor-positive breast cancer, axillary staging and adjuvant radiotherapy provide no survival advantage over surgery and hormone therapy alone. Despite recommendations for their omission, sentinel lymph node biopsy (SLNB) and adjuvant radiotherapy rates remain high. While treatment side effects are well documented, less is known about the incremental spending associated with SLNB and adjuvant radiotherapy.METHODS: Using a statewide multipayer claims registry, we examined spe...
Source: Ann Oncol - September 23, 2021 Category: Cancer & Oncology Authors: Brooke C Bredbeck Alison S Baskin Ton Wang Brandy R Sinco Nicholas L Berlin Sarah P Shubeck Nicole M Mott Rachel A Greenup Hari Nathan Tasha M Hughes Lesly A Dossett Source Type: research

Imaging Features for Predicting High-Grade Dysplasia or Malignancy in Branch Duct Type Intraductal Papillary Mucinous Neoplasm of the Pancreas: A Systematic Review and Meta-Analysis
CONCLUSIONS: The aforementioned imaging features could aid in predicting HGD/malignancy of BD-IPMN. Furthermore, enhanced solid component/MN and an MPD diameter of 10 mm or greater were the most important predictors of HGD/malignancy in BD-IPMN and should be considered as indications for surgery.PMID:34554343 | DOI:10.1245/s10434-021-10662-2 (Source: Ann Oncol)
Source: Ann Oncol - September 23, 2021 Category: Cancer & Oncology Authors: Wenjing Zhao Shanglong Liu Lin Cong Yupei Zhao Source Type: research

Reply to T. Shimoi et al and Y. Shimanuki et al
J Clin Oncol. 2021 Sep 23:JCO2101905. doi: 10.1200/JCO.21.01905. Online ahead of print.NO ABSTRACTPMID:34554848 | DOI:10.1200/JCO.21.01905 (Source: Ann Oncol)
Source: Ann Oncol - September 23, 2021 Category: Cancer & Oncology Authors: Ingrid A Mayer Fengmin Zhao Carlos L Arteaga William F Symmans Ben H Park Brian L Burnette Amye J Tevaarwerk Sofia F Garcia Karen L Smith Della F Makower Margaret Block Kimberly A Morley Chirag R Jani Craig Mescher Shabana J Dewani Bernard Tawfik Lisa E F Source Type: research

Toxicity Index, Patient-Reported Outcomes, and Early Discontinuation of Endocrine Therapy for Breast Cancer Risk Reduction in NRG Oncology/NSABP B-35
J Clin Oncol. 2021 Sep 23:JCO2100910. doi: 10.1200/JCO.21.00910. Online ahead of print.ABSTRACT[Figure: see text].PMID:34554865 | DOI:10.1200/JCO.21.00910 (Source: Ann Oncol)
Source: Ann Oncol - September 23, 2021 Category: Cancer & Oncology Authors: N Lynn Henry Sungjin Kim Ron D Hays Marcio A Diniz Michael Luu Reena S Cecchini Greg Yothers Andr é Rogatko Patricia A Ganz Source Type: research

Impact of the methylation classifier and ancillary methods on CNS tumor diagnostics
CONCLUSIONS: This work assesses the impact of a methylation classifier and additional methods in a consultative practice by defining the proportions with concordant vs. change in diagnosis in a set of diagnostically challenging CNS tumors. We address approaches to low-confidence scores and confounding issues of low tumor purity.PMID:34555175 | DOI:10.1093/neuonc/noab227 (Source: Ann Oncol)
Source: Ann Oncol - September 23, 2021 Category: Cancer & Oncology Authors: Zhichao Wu Zied Abdullaev Drew Pratt Hye-Jung Chung Shannon Skarshaug Valerie Zgonc Candice Perry Svetlana Pack Lola Saidkhodjaeva Sushma Nagaraj Manoj Tyagi Vineela Gangalapudi Kristin Valdez Rust Turakulov Liqiang Xi Mark Raffeld Antonios Papanicolau-Se Source Type: research

Hesitancy around low dose CT screening for lung cancer
Ann Oncol. 2021 Sep 20:S0923-7534(21)04487-2. doi: 10.1016/j.annonc.2021.09.008. Online ahead of print.ABSTRACTLung cancer is the leading cause of cancer death worldwide. The absence of symptoms in early stage (I/II) disease, when curative treatment is possible, results in greater than 70% of cases being diagnosed at late stage (III/IV), when treatment is rarely curative. This contributes greatly to lung cancer's poor prognosis which sees only 16.2% of individuals diagnosed with the disease alive at 5 years. Early detection is key to improving lung cancer survival outcomes. As a result, there has been longstanding interest...
Source: Ann Oncol - September 23, 2021 Category: Cancer & Oncology Authors: J L Dickson C Horst A Nair S Tisi R Prendecki S M Janes Source Type: research

Effects of active cancer treatment on safety and immunogenicity of COVID-19 mRNA-BNT162b2 vaccine: Preliminary results from the prospective observational Vax-On study
Ann Oncol. 2021 Sep 20:S0923-7534(21)04488-4. doi: 10.1016/j.annonc.2021.09.009. Online ahead of print.NO ABSTRACTPMID:34555502 | PMC:PMC8452134 | DOI:10.1016/j.annonc.2021.09.009 (Source: Ann Oncol)
Source: Ann Oncol - September 23, 2021 Category: Cancer & Oncology Authors: F Nelli A Fabbri A Onorato D Giannarelli M A Silvestri J R Giron Berrios A Virtuoso E Marrucci C Signorelli M G Chilelli F Primi M Schirripa M Mazzotta E M Ruggeri Source Type: research

Patient-reported outcome changes at the end of life in recurrent platinum-resistant ovarian cancer: An NRG oncology/GOG study
Gynecol Oncol. 2021 Sep 18:S0090-8258(21)01326-3. doi: 10.1016/j.ygyno.2021.08.028. Online ahead of print.ABSTRACTOBJECTIVES: In a prospective study of platinum-resistant ovarian cancer patients, we examined whether the Disease-related Symptoms-Physical (DRS--P) scale of the NCCN/FACT-Ovarian Cancer Symptom Index-18 (NFOSI-18) is responsive to clinical change in patients estimated by their provider to survive at least six months.METHODS: The NFOSI-18, and other FACT measures, was collected at study entry and 3 and 6 months post-enrollment. Measures were compared for those who died or dropped off study prior to 3 months or ...
Source: Ann Oncol - September 22, 2021 Category: Cancer & Oncology Authors: Lari Wenzel Helen Q Huang David Cella Chelsea O McKinney Michael A Zevon Jason A LaChance Joan L Walker Ritu Salani Susan C Modesitt Robert T Morris William H Bradley Matthew P Boente Vivian E von Gruenigen Source Type: research

ASO Visual Abstract: PET Imaging and Rate of Pathologic Complete Response in Esophageal Squamous Cell Carcinoma
Ann Surg Oncol. 2021 Sep 21. doi: 10.1245/s10434-021-10691-x. Online ahead of print.NO ABSTRACTPMID:34549361 | DOI:10.1245/s10434-021-10691-x (Source: Ann Oncol)
Source: Ann Oncol - September 22, 2021 Category: Cancer & Oncology Authors: M Hart Squires Nicole Gower Jennifer H Benbow Erin E Donahue Casey E Bohl Roshan S Prabhu Joshua S Hill Jonathan C Salo Source Type: research

Predictors of Postoperative Liver Decompensation Events After Resection in Patients with Cirrhosis and Hepatocellular Carcinoma: A Population-Based Study
CONCLUSIONS: Among patients with cirrhosis undergoing resection for HCC, patient and disease-related factors are associated with POLDEs and POLDE-free survival. These factors can be used both to inform clinical practice and to advance the development of preoperative prognostic tools, which may lead to improved outcomes for this population.PMID:34549362 | DOI:10.1245/s10434-021-10801-9 (Source: Ann Oncol)
Source: Ann Oncol - September 22, 2021 Category: Cancer & Oncology Authors: Zuhaib M Mir Maya Djerboua Sulaiman Nanji Jennifer A Flemming Patti A Groome Source Type: research

Anatomic Resection for Hepatocellular Carcinoma: Prognostic Impact Assessed from Recurrence Treatment
This study aimed to evaluate the clinical advantages of AR for primary HCC by using propensity score-matching and by assessing treatment strategies for recurrence after surgery.METHODS: The study reviewed data of patients who underwent AR or non-anatomic resection (NAR) for solitary HCC (≤ 5 cm) in two institutions between 2004 and 2017. Surgical outcomes were compared between the two groups in a propensity score-adjusted cohort. The time-to-interventional failure (TIF), defined as the elapsed time from resection to unresectable/unablatable recurrence, also was evaluated.RESULTS: The inclusion criteria were met by 250 p...
Source: Ann Oncol - September 22, 2021 Category: Cancer & Oncology Authors: Masaaki Minagawa Yoshihiro Mise Kiyohiko Omichi Hirofumi Ichida Tomoya Mizuno Ryuji Yoshioka Hiroshi Imamura Naotake Yanagisawa Yosuke Inoue Yu Takahashi Akio Saiura Source Type: research

ASO Visual Abstract: Robotic Surgery in Pediatric Oncology-Lessons Learned from the First 100 Tumors: A Nationwide Experience
Ann Surg Oncol. 2021 Sep 21. doi: 10.1245/s10434-021-10850-0. Online ahead of print.NO ABSTRACTPMID:34549364 | DOI:10.1245/s10434-021-10850-0 (Source: Ann Oncol)
Source: Ann Oncol - September 22, 2021 Category: Cancer & Oncology Authors: Thomas Blanc Pierre Meignan Nicolas Vinit Quentin Ballouhey Luca Pio Carmen Capito Caroline Harte Fabrizio Vatta Louise Galmiche-Rolland V éronique Minard Daniel Orbach Laureline Berteloot C écile Muller Jules Kohaut Aline Broch Karim Braik Aur élien B Source Type: research

ASO Author Reflections: Incomplete Cytoreduction Prediction Model for Pseudomyxoma Peritonei
Ann Surg Oncol. 2021 Sep 21. doi: 10.1245/s10434-021-10817-1. Online ahead of print.NO ABSTRACTPMID:34549365 | DOI:10.1245/s10434-021-10817-1 (Source: Ann Oncol)
Source: Ann Oncol - September 22, 2021 Category: Cancer & Oncology Authors: Mingjian Bai Hongbin Xu Man Zhang Source Type: research

ASO Author Reflections: Improving Quality of Life for Patients With Malignant Bowel Obstructions: A Role for Transesophageal Gastrostomy Tubes
Ann Surg Oncol. 2021 Sep 22. doi: 10.1245/s10434-021-10816-2. Online ahead of print.NO ABSTRACTPMID:34550477 | DOI:10.1245/s10434-021-10816-2 (Source: Ann Oncol)
Source: Ann Oncol - September 22, 2021 Category: Cancer & Oncology Authors: Clara Zhu Young K Hong Source Type: research

Early Diagnosis of Anastomotic Leakage After Gastric Cancer Surgery Via Analysis of Inflammatory Factors in Abdominal Drainage
CONCLUSIONS: Our study suggests that AL can be early diagnosed after gastric cancer surgery by measuring drainage IFs.PMID:34550478 | DOI:10.1245/s10434-021-10763-y (Source: Ann Oncol)
Source: Ann Oncol - September 22, 2021 Category: Cancer & Oncology Authors: Jinyao Shi Zhouqiao Wu Xiaolong Wu Fei Shan Yan Zhang Xiangji Ying Ziyu Li Jiafu Ji Source Type: research

Estimating Surgical Outcomes for Hepatocellular Carcinoma
Ann Surg Oncol. 2021 Sep 22. doi: 10.1245/s10434-021-10832-2. Online ahead of print.NO ABSTRACTPMID:34550479 | DOI:10.1245/s10434-021-10832-2 (Source: Ann Oncol)
Source: Ann Oncol - September 22, 2021 Category: Cancer & Oncology Authors: Curtis J Wray Source Type: research

ASO Visual Abstract: Omission of Right Hemicolectomy  May be Safe for Some Appendiceal Goblet Cell Adenocarcinomas-A Survival Analysis of the National Cancer Database
Ann Surg Oncol. 2021 Sep 22. doi: 10.1245/s10434-021-10256-y. Online ahead of print.NO ABSTRACTPMID:34550480 | DOI:10.1245/s10434-021-10256-y (Source: Ann Oncol)
Source: Ann Oncol - September 22, 2021 Category: Cancer & Oncology Authors: Stacy J Kowalsky Ibrahim Nassour Samer AlMasri Alessandro Paniccia Amer H Zureikat Haroon A Choudry James F Pingpank Source Type: research

Outcomes of Fertility Preservation Consults for Women at Risk for Primary Ovarian Insufficiency Due to History of Cancer Treatment or Mosaic Turner Syndrome
We report consult/treatment outcomes for 21 cancer survivors and 3 mosaic Turner syndrome (TS) patients (mean age 21.6 at consult, 3 with POI). Ten AYAs (9 survivors, 1 mosaic TS) attempted ovarian stimulation; 4 cancelled for poor response. Of completed cycles, mean 3.8 mature oocytes were retrieved, with mean anti-Müllerian hormone 0.653 ng/mL. Ovarian stimulation for mosaic TS AYA and survivors is possible, even with diminished ovarian reserve. Further study is needed to establish guidelines for patient selection, treatment timing, and stimulation protocols.PMID:34550775 | DOI:10.1089/jayao.2021.0115 (Source: Ann Oncol)
Source: Ann Oncol - September 22, 2021 Category: Cancer & Oncology Authors: Nicole D Ulrich Nicholas Raja Erin Ellman Molly B Moravek Source Type: research

Patient-reported outcome changes at the end of life in recurrent platinum-resistant ovarian cancer: An NRG oncology/GOG study
Gynecol Oncol. 2021 Sep 18:S0090-8258(21)01326-3. doi: 10.1016/j.ygyno.2021.08.028. Online ahead of print.ABSTRACTOBJECTIVES: In a prospective study of platinum-resistant ovarian cancer patients, we examined whether the Disease-related Symptoms-Physical (DRS--P) scale of the NCCN/FACT-Ovarian Cancer Symptom Index-18 (NFOSI-18) is responsive to clinical change in patients estimated by their provider to survive at least six months.METHODS: The NFOSI-18, and other FACT measures, was collected at study entry and 3 and 6 months post-enrollment. Measures were compared for those who died or dropped off study prior to 3 months or ...
Source: Ann Oncol - September 22, 2021 Category: Cancer & Oncology Authors: Lari Wenzel Helen Q Huang David Cella Chelsea O McKinney Michael A Zevon Jason A LaChance Joan L Walker Ritu Salani Susan C Modesitt Robert T Morris William H Bradley Matthew P Boente Vivian E von Gruenigen Source Type: research

ASO Visual Abstract: PET Imaging and Rate of Pathologic Complete Response in Esophageal Squamous Cell Carcinoma
Ann Surg Oncol. 2021 Sep 21. doi: 10.1245/s10434-021-10691-x. Online ahead of print.NO ABSTRACTPMID:34549361 | DOI:10.1245/s10434-021-10691-x (Source: Ann Oncol)
Source: Ann Oncol - September 22, 2021 Category: Cancer & Oncology Authors: M Hart Squires Nicole Gower Jennifer H Benbow Erin E Donahue Casey E Bohl Roshan S Prabhu Joshua S Hill Jonathan C Salo Source Type: research

Predictors of Postoperative Liver Decompensation Events After Resection in Patients with Cirrhosis and Hepatocellular Carcinoma: A Population-Based Study
CONCLUSIONS: Among patients with cirrhosis undergoing resection for HCC, patient and disease-related factors are associated with POLDEs and POLDE-free survival. These factors can be used both to inform clinical practice and to advance the development of preoperative prognostic tools, which may lead to improved outcomes for this population.PMID:34549362 | DOI:10.1245/s10434-021-10801-9 (Source: Ann Oncol)
Source: Ann Oncol - September 22, 2021 Category: Cancer & Oncology Authors: Zuhaib M Mir Maya Djerboua Sulaiman Nanji Jennifer A Flemming Patti A Groome Source Type: research

Anatomic Resection for Hepatocellular Carcinoma: Prognostic Impact Assessed from Recurrence Treatment
This study aimed to evaluate the clinical advantages of AR for primary HCC by using propensity score-matching and by assessing treatment strategies for recurrence after surgery.METHODS: The study reviewed data of patients who underwent AR or non-anatomic resection (NAR) for solitary HCC (≤ 5 cm) in two institutions between 2004 and 2017. Surgical outcomes were compared between the two groups in a propensity score-adjusted cohort. The time-to-interventional failure (TIF), defined as the elapsed time from resection to unresectable/unablatable recurrence, also was evaluated.RESULTS: The inclusion criteria were met by 250 p...
Source: Ann Oncol - September 22, 2021 Category: Cancer & Oncology Authors: Masaaki Minagawa Yoshihiro Mise Kiyohiko Omichi Hirofumi Ichida Tomoya Mizuno Ryuji Yoshioka Hiroshi Imamura Naotake Yanagisawa Yosuke Inoue Yu Takahashi Akio Saiura Source Type: research

ASO Visual Abstract: Robotic Surgery in Pediatric Oncology-Lessons Learned from the First 100 Tumors: A Nationwide Experience
Ann Surg Oncol. 2021 Sep 21. doi: 10.1245/s10434-021-10850-0. Online ahead of print.NO ABSTRACTPMID:34549364 | DOI:10.1245/s10434-021-10850-0 (Source: Ann Oncol)
Source: Ann Oncol - September 22, 2021 Category: Cancer & Oncology Authors: Thomas Blanc Pierre Meignan Nicolas Vinit Quentin Ballouhey Luca Pio Carmen Capito Caroline Harte Fabrizio Vatta Louise Galmiche-Rolland V éronique Minard Daniel Orbach Laureline Berteloot C écile Muller Jules Kohaut Aline Broch Karim Braik Aur élien B Source Type: research

ASO Author Reflections: Incomplete Cytoreduction Prediction Model for Pseudomyxoma Peritonei
Ann Surg Oncol. 2021 Sep 21. doi: 10.1245/s10434-021-10817-1. Online ahead of print.NO ABSTRACTPMID:34549365 | DOI:10.1245/s10434-021-10817-1 (Source: Ann Oncol)
Source: Ann Oncol - September 22, 2021 Category: Cancer & Oncology Authors: Mingjian Bai Hongbin Xu Man Zhang Source Type: research

ASO Author Reflections: Improving Quality of Life for Patients With Malignant Bowel Obstructions: A Role for Transesophageal Gastrostomy Tubes
Ann Surg Oncol. 2021 Sep 22. doi: 10.1245/s10434-021-10816-2. Online ahead of print.NO ABSTRACTPMID:34550477 | DOI:10.1245/s10434-021-10816-2 (Source: Ann Oncol)
Source: Ann Oncol - September 22, 2021 Category: Cancer & Oncology Authors: Clara Zhu Young K Hong Source Type: research

Early Diagnosis of Anastomotic Leakage After Gastric Cancer Surgery Via Analysis of Inflammatory Factors in Abdominal Drainage
CONCLUSIONS: Our study suggests that AL can be early diagnosed after gastric cancer surgery by measuring drainage IFs.PMID:34550478 | DOI:10.1245/s10434-021-10763-y (Source: Ann Oncol)
Source: Ann Oncol - September 22, 2021 Category: Cancer & Oncology Authors: Jinyao Shi Zhouqiao Wu Xiaolong Wu Fei Shan Yan Zhang Xiangji Ying Ziyu Li Jiafu Ji Source Type: research