Early gastric cancer accompanying Gastritis cystica profunda with a Giant cyst
Intern Med. 2024 Apr 23. doi: 10.2169/internalmedicine.3460-24. Online ahead of print.NO ABSTRACTPMID:38658339 | DOI:10.2169/internalmedicine.3460-24 (Source: Internal Medicine)
Source: Internal Medicine - April 24, 2024 Category: Internal Medicine Authors: Hironao Matsumoto Takeshi Yamashina Masaaki Shimatani Source Type: research
Identification of Key lncRNAs Associated with Immune Infiltration and Prognosis in Gastric Cancer
In this study, we systematically analyzed lncRNA and miRNA transcriptomic profiles of GC based on bioinformatics methods and experimental validation. An lncRNA-miRNA interaction network related to GC was constructed, and the nine crucial lncRNAs were identified. These 9 lncRNAs were found to be associated with the prognosis of GC patients by Cox proportional hazards regression analysis. Among them, the expression of lncRNA SNHG14 can affect the survival of GC patients as a potential prognostic marker. Moreover, it was shown that SNHG14 was involved in immune-related pathways and significantly correlated with immune cell in...
Source: Biochemical Genetics - April 24, 2024 Category: Genetics & Stem Cells Authors: Wen Jin Jianchao Jia Yangming Si Jianli Liu Hanshuang Li Hao Zhu Zhouying Wu Yongchun Zuo Lan Yu Source Type: research
Early gastric cancer accompanying Gastritis cystica profunda with a Giant cyst
Intern Med. 2024 Apr 23. doi: 10.2169/internalmedicine.3460-24. Online ahead of print.NO ABSTRACTPMID:38658339 | DOI:10.2169/internalmedicine.3460-24 (Source: Internal Medicine)
Source: Internal Medicine - April 24, 2024 Category: Internal Medicine Authors: Hironao Matsumoto Takeshi Yamashina Masaaki Shimatani Source Type: research
Integrated multi-omics analysis and machine learning identify hub genes and potential mechanisms of resistance to immunotherapy in gastric cancer
CONCLUSIONS: The results unveil an association between CDH6, EGFLAM, and RASGRF2 and the immunotherapeutic response in gastric cancer. These genes hold potential as predictive biomarkers for gastric cancer immunotherapy resistance and prognostic assessment.PMID:38656888 | DOI:10.18632/aging.205760 (Source: Aging)
Source: Aging - April 24, 2024 Category: Biomedical Science Authors: Jinsong Wang Jia Feng Xinyi Chen Yiming Weng Tong Wang Jiayan Wei Yujie Zhan Min Peng Source Type: research
Corrigendum to "HSF1, in association with MORC2, downregulates ArgBP2 via the PRC2 family in gastric cancer cells" [Biochim. Biophys. Acta. Mol. Basis. Dis. 2018 Apr;1864(4 Pt A):1104-1114/PMID: 29339121]
Biochim Biophys Acta Mol Basis Dis. 2024 Apr 23:167199. doi: 10.1016/j.bbadis.2024.167199. Online ahead of print.NO ABSTRACTPMID:38658217 | DOI:10.1016/j.bbadis.2024.167199 (Source: Biochimica et Biophysica Acta)
Source: Biochimica et Biophysica Acta - April 24, 2024 Category: Biochemistry Authors: Yuxin Tong Yan Li Hui Gu Chunyu Wang Funan Liu Yangguang Shao Feng Li Source Type: research
Early gastric cancer accompanying Gastritis cystica profunda with a Giant cyst
Intern Med. 2024 Apr 23. doi: 10.2169/internalmedicine.3460-24. Online ahead of print.NO ABSTRACTPMID:38658339 | DOI:10.2169/internalmedicine.3460-24 (Source: Internal Medicine)
Source: Internal Medicine - April 24, 2024 Category: Internal Medicine Authors: Hironao Matsumoto Takeshi Yamashina Masaaki Shimatani Source Type: research
Identification of Key lncRNAs Associated with Immune Infiltration and Prognosis in Gastric Cancer
In this study, we systematically analyzed lncRNA and miRNA transcriptomic profiles of GC based on bioinformatics methods and experimental validation. An lncRNA-miRNA interaction network related to GC was constructed, and the nine crucial lncRNAs were identified. These 9 lncRNAs were found to be associated with the prognosis of GC patients by Cox proportional hazards regression analysis. Among them, the expression of lncRNA SNHG14 can affect the survival of GC patients as a potential prognostic marker. Moreover, it was shown that SNHG14 was involved in immune-related pathways and significantly correlated with immune cell in...
Source: Biochemical Genetics - April 24, 2024 Category: Genetics & Stem Cells Authors: Wen Jin Jianchao Jia Yangming Si Jianli Liu Hanshuang Li Hao Zhu Zhouying Wu Yongchun Zuo Lan Yu Source Type: research
Reactivating Hippo by Drug Compounds to Suppress Gastric Cancer and Enhance Chemotherapy Sensitivity
J Biol Chem. 2024 Apr 22:107311. doi: 10.1016/j.jbc.2024.107311. Online ahead of print.ABSTRACTThe Hippo signaling pathway plays an essential role in organ size control and tumorigenesis. Loss of Hippo signal and hyper-activation of the downstream oncogenic YAP signaling are commonly observed in various types of cancers. We previously identified STRN3-containing PP2A phosphatase as a negative regulator of MST1/2 kinases (i.e. Hippo) in gastric cancer (GC), opening the possibility of selectively targeting the PP2Aa-STRN3-MST1/2 axis to recover Hippo signaling against cancer. Here, we further discovered 1) disulfiram (DSF), ...
Source: Cancer Control - April 24, 2024 Category: Cancer & Oncology Authors: Zhifa Cao Yu Hou Zhangting Zhao Hui Zhang Luyang Tian Yiming Zhang Chao Dong Fenghua Guo Lijie Tan Yi Han Wenjia Wang Shi Jiao Yang Tang Liwei An Zhaocai Zhou Source Type: research
Integrated multi-omics analysis and machine learning identify hub genes and potential mechanisms of resistance to immunotherapy in gastric cancer
CONCLUSIONS: The results unveil an association between CDH6, EGFLAM, and RASGRF2 and the immunotherapeutic response in gastric cancer. These genes hold potential as predictive biomarkers for gastric cancer immunotherapy resistance and prognostic assessment.PMID:38656888 | DOI:10.18632/aging.205760 (Source: Aging)
Source: Aging - April 24, 2024 Category: Biomedical Science Authors: Jinsong Wang Jia Feng Xinyi Chen Yiming Weng Tong Wang Jiayan Wei Yujie Zhan Min Peng Source Type: research
UBE2L3 expression in human gastric cancer and its clinical significance
CONCLUSIONS: The findings of our study demonstrate the significant involvement of UBE2L3 in the pathogenesis and advancement of gastric cancer, suggesting its potential as a therapeutic target.PMID:38656363 | DOI:10.1007/s00432-024-05669-7 (Source: Cell Research)
Source: Cell Research - April 24, 2024 Category: Cytology Authors: Xiaoxia Zhang Yujie Wei Fanqi Wu Mei Li Cong Han Chengdong Huo Zhi Li Futian Tang Wenting He Yang Zhao Yumin Li Source Type: research
Modified Q-type purse-string suture duodenal stump embedding method for laparoscopic gastrectomy for gastric cancer
This study introduced the modified Q-type purse-string suture duodenal stump embedding method, a convenient way to strengthen the duodenum, and compared it to the conventional one to assess its efficacy and sa... (Source: BMC Surgery)
Source: BMC Surgery - April 24, 2024 Category: Surgery Authors: Longhe Sun, Wei Wang, Jiajie Zhou, Lili Ji, Shuai Zhao, Yayan Fu, Ruiqi Li, Jie Wang, Chunhua Qian, Qiannan Sun and Daorong Wang Tags: Research Source Type: research
UBE2L3 expression in human gastric cancer and its clinical significance
ConclusionsThe findings of our study demonstrate the significant involvement of UBE2L3 in the pathogenesis and advancement of gastric cancer, suggesting its potential as a therapeutic target. (Source: Journal of Cancer Research and Clinical Oncology)
Source: Journal of Cancer Research and Clinical Oncology - April 24, 2024 Category: Cancer & Oncology Source Type: research
