Log in to search using one of your social media accounts:

 

Cerebrotendinous Xanthomatosis with Nodular-hypertrophy of the Lumbosacral Roots.
Authors: Hashimoto T, Sennari Y, Okada K, Adachi H PMID: 29321402 [PubMed - as supplied by publisher] (Source: Internal Medicine)
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

A Patient with a Massive Single Cardiac Metastasis of Lung Adenocarcinoma, Diagnosed via a Biopsy: A Case Report.
Authors: Oyakawa T, Muraoka N, Iida K, Kusuhara M, Naito T Abstract A patient with a history of lung adenocarcinoma was admitted because of palpitation. Transthoracic echocardiogram revealed a mass (74×42 mm) in the right ventricle. Computed tomography showed a tumor lesion in the right ventricular cavity but no other distant metastasis. Coronary angiography revealed well-developed small branches to the tumor. After right heart catheterization, a pathological analysis of a tumor biopsy demonstrated adenocarcinoma. We diagnosed the patient with right ventricular metastasis of lung cancer. With large cardiac me...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

A Clinicopathological Analysis of Six Autopsy Cases of Sudden Unexpected Death Due to Infectious Aortitis in Patients with Aortic Tears.
Discussion We demonstrated that sudden unexpected death caused by infectious aortitis rarely occurred in hospitalized patients, even in the recovery phase of the preceding infectious disease. We therefore recommend that clinicians pay attention to infectious aortitis in patients with infectious disease, particularly elderly patients with atherosclerotic disease, even those who are in the improvement phase. Highlights Unexpected sudden death by infectious aortitis in the recovery phase of antecedent infection. PMID: 29321404 [PubMed - as supplied by publisher] (Source: Internal Medicine)
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Reversible Parkinsonism and Multiple Cerebral Infarctions after Pulmonary Endarterectomy in a Patient with Antiphospholipid Syndrome.
Authors: Okano M, Nakayama K, Tamada N, Shinkura Y, Yanaka KI, Onishi H, Tanaka H, Shinke T, Tanaka H, Okita Y, Emoto N, Hirata KI Abstract Antiphospholipid syndrome (APS) is a cause of chronic thromboembolic pulmonary hypertension (CTEPH) and it is associated with an increased risk of postoperative neurological complications. We experienced a case of reversible parkinsonism after pulmonary endarterectomy (PEA) and subsequent multiple cerebral infarctions under standard anticoagulation therapy in a patient with CTEPH associated with APS. Strict management using a combination of antiplatelet and anticoagulation ther...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

An Acute Case of Granulomatous Amoebic Encephalitis-Balamuthia Mandrillaris Infection.
Authors: Takei K, Toyoshima M, Nakamura M, Sato M, Shimizu H, Inoue C, Shimizu Y, Yagita K Abstract A 74-year-old woman who exhibited drowsiness was referred to our hospital. Enhanced head magnetic resonance imaging (MRI) revealed multiple ring-enhancing lesions and lesions showing partial mild hemorrhaging. The patient gradually progressed to a comatose condition with notable brain deterioration of unknown cause on follow-up MRI. On day nine, the patient inexplicably died, although brain herniation was suspected. Autopsy and histopathology revealed numerous amoebic trophozoites in the perivascular spaces and withi...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Vertebral Osteomyelitis Caused by Helicobacter cinaedi Identified Using Broad-range Polymerase Chain Reaction with Sequencing of the Biopsied Specimen.
Authors: Hase R, Hirooka T, Itabashi T, Endo Y, Otsuka Y Abstract A 65-year-old man presented with gradually exacerbating low back pain. Magnetic resonance imaging revealed vertebral osteomyelitis in the Th11-L2 vertebral bodies and discs. The patient showed negative findings on conventional cultures. Direct broad-range polymerase chain reaction (PCR) with sequencing of the biopsied specimen had the highest similarity to the 16S rRNA gene of Helicobacter cinaedi. This case suggests that direct broad-range PCR with sequencing should be considered when conventional cultures cannot identify the causative organism of v...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

The Factors Affecting the Non-dipper Pattern in Japanese Patients with Severe Obstructive Sleep Apnea.
This study aimed to clarify the triggers of the non-dipper pattern in nocturnal BP in Japanese patients with severe OSA (the apnea-hypopnea index ≥30/h). Methods Of 541 patients with OSA diagnosed using polysomnography (PSG) and ambulatory BP monitoring (ABPM), 163 patients
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Pulmonary Embolism Caused by Intravenous Leiomyosarcoma of the Lower Limb.
We report the long-term survival of a patient with PE due to a leiomyosarcoma in the deep vein. A 71-year-old woman complained of dyspnea and swelling of the left lower limb. Computed tomography revealed filling defects in the pulmonary arteries and deep vein. She was diagnosed with PE caused by venous thrombosis and treated with anticoagulant therapy. Her symptoms were prolonged, and D-dimer tests remained negative. Biopsy of the substance in the deep vein revealed leiomyosarcoma. The possibility of PE caused by extravascular or intravascular tumors should be considered when a patient is negative for D-dimer. PMID: 29...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Successful Management of Pregnancy in a Patient with Systemic Lupus Erythematosus-associated Pulmonary Arterial Hypertension.
Authors: Kawabe A, Nakano K, Aiko Y, Aramaki S, Onoue T, Okura D, Tanaka Y Abstract Pregnancy in women with systemic lupus erythematosus (SLE)-associated pulmonary arterial hypertension (PAH) remains a high risk. We successfully managed a pregnancy in a patient with SLE-PAH. A 31-year-old pregnant woman with SLE-PAH had worsening PAH and SLE flare-up during pregnancy and a sudden increase in pulmonary arterial pressure after delivery. SLE-PAH was controlled by continuous intravenous epoprostenol and inhaled nitric oxide therapy combined with high-dose corticosteroids under close hemodynamic monitoring. Women with S...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Cough Headache Presenting with Reversible Cerebral Vasoconstriction Syndrome: A Case Report.
Authors: Kato Y, Hayashi T, Sano H, Kato R, Tanahashi N, Takao M Abstract Cough headache can be a primary benign condition or secondary to underlying etiologies. We herein describe a case of a 52-year-old woman with cough headache that presented as reversible cerebral vasoconstriction syndrome (RCVS). Some cases of RCVS are caused by an aberrant sympathetic response to activities that cause an intracranial pressure surge. Therefore, cough headache should be recognized as a possible presentation of RCVS, even without thunderclap headache or neurological deficits. PMID: 29321411 [PubMed - as supplied by publisher...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

The Successful Treatment of Sodium Polystyrene Sulfonate-induced Enteritis Diagnosed by Small Bowel Endoscopy.
Authors: Okayama K, Hirata Y, Kumai D, Yamamoto Y, Kojima Y, Kanno T, Ikeuchi H, Mochizuki H, Takada H, Sobue S Abstract Sodium polystyrene sulfonate (SPS: Kayexalate®) is an ion-exchange resin used to treat hyperkalemia in patients with chronic kidney disease. It is known that this resin sometimes causes colonic necrosis and perforation, but there are few reports about small bowel necrosis associated with SPS. We herein report the case of a patient who developed SPS-induced small bowel necrosis, which was diagnosed based on the examination of a small bowel endoscopic biopsy specimen. The SPS-induced small bowe...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Remission of Refractory Ascites and Discontinuation of Hemodialysis after Additional Rituximab to Long-term Glucocorticoid Therapy in a Patient with TAFRO Syndrome.
We reported a 50-year-old woman with TAFRO syndrome diagnosed 2 years after the initial symptoms of a fever, fatigue, epigastric pain, edema, ascites, lymphadenopathy, thrombocytopenia and renal insufficiency. The patient showed refractory ascites and required hemodialysis under corticosteroid mono-therapy for suspected immune-mediated disease but was successfully treated with additive rituximab, resulting in improvement in her laboratory data, the withdrawal of hemodialysis and the disappearance of ascites. This case underscores the therapeutic utility of rituximab in patients with corticosteroid-resistant TAFRO syndrome,...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

The Platelet Count can Predict In-hospital Death in HIV-negative Smear-positive Pulmonary Tuberculosis Inpatients.
Authors: Goto H, Horita N, Tashiro K, Nagai K, Yamamoto M, Sato T, Hara Y, Nagakura H, Shibata Y, Watanabe H, Nakashima K, Ushio R, Nagashima A, Ikeda M, Narita A, Sasaki K, Kobayashi N, Kudo M, Kaneko T Abstract Introduction This retrospective cohort study investigated whether the three components of the blood cell count have prognostic implications in HIV-negative Japanese adult inpatients with smear-positive pulmonary tuberculosis. Methods We reviewed patients who were treated by the isoniazid, rifampicin, pyrazinamide, and ethambutol regimen or by the isoniazid, rifampicin, and ethambutol regimen. The associati...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Cerebral Toxoplasmosis Diagnosed by Nested-Polymerase Chain Reaction in a Patient with Rheumatoid Arthritis.
Authors: Matsuura J, Fujii A, Mizuta I, Norose K, Mizuno T Abstract A 65-year-old woman with rheumatoid arthritis (RA) visited our hospital because of right facial sensory hypoesthesia. Cerebral toxoplasmosis was suspected on brain magnetic resonance imaging. We discontinued methotrexate for RA and started a sulfamethoxazole/trimethoprim (ST) mixture. Although ST treatment was interrupted because of adverse reactions, her prognosis was favorable. The Toxoplasma 18S rDNA gene was detected by nested-polymerase chain reaction (PCR) from blood and cerebrospinal fluid. Detecting the Toxoplasma 18S rDNA gene by nested-PC...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Simultaneous Nontraumatic Spinal and Intracranial Subdural Hematoma.
Authors: Wada Y, Kitano T, Uemura J, Yagita Y PMID: 29321416 [PubMed - as supplied by publisher] (Source: Internal Medicine)
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Peripheral Ulcerative Keratitis Associated with Granulomatosis with Polyangiitis Emerging Despite Cyclophosphamide, Successfully Treated with Rituximab.
Authors: Fujita Y, Fukui S, Endo Y, Tsuji S, Takatani A, Shimizu T, Umeda M, Nishino A, Koga T, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Ueki R, Uematsu M, Ishida K, Abe K, Kawakami A Abstract A 67-year-old Japanese man was diagnosed with granulomatosis with polyangiitis based on the presence of right maxillary sinusitis, proteinase 3 antineutrophil cytoplasmic antibody positivity, and right scleritis. A conjunctival biopsy specimen showed neutrophil-predominant infiltration around the vessels without granuloma. Because there was a risk of blindness, pulsed methylprednisolone and intrav...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Optimal Medications and Appropriate Implantable Cardioverter-defibrillator Shocks in Aborted Sudden Cardiac Death Due to Coronary Spasm.
Authors: Sueda S, Kohno H Abstract Background Life-threatening ventricular arrhythmias are recognized in patients with coronary spastic angina. Implantable cardioverter-defibrillators (ICDs) are effective in patients with structural heart disease and ventricular fibrillation. However, the optimal medication for patients with aborted sudden cardiac death (SCD) due to coronary artery spasm after the implantation of ICD remains controversial. Methods We investigated the medications and the numbers of appropriate ICD shocks in 137 patients with a history of aborted SCD due to coronary spasm. Results Appropriate ICD sho...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Useful Predictive Factors for Bacteremia among Outpatients with Pyelonephritis.
Conclusion Bacteremia should be considered in pyelonephritis patients with rapidly assessable factors in outpatient clinic. In particular, a model including a urinary nitrite test has the potential to aid in the prediction of bacteremia. PMID: 29321419 [PubMed - as supplied by publisher] (Source: Internal Medicine)
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Validity of the Pre-endoscopic Scoring Systems for the Prediction of the Failure of Endoscopic Hemostasis in Bleeding Gastroduodenal Peptic Ulcers.
Conclusion The GBS was the most useful scoring system for the prediction of failure of endoscopic hemostasis in patients with bleeding gastroduodenal peptic ulcers. The GBS was also useful in identifying the patients who did not require surgery or interventional radiology. PMID: 29321420 [PubMed - as supplied by publisher] (Source: Internal Medicine)
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

A Fatal Case of Super-super Obesity (BMI > 80) in a Patient with a Necrotic Soft Tissue Infection.
A Fatal Case of Super-super Obesity (BMI>80) in a Patient with a Necrotic Soft Tissue Infection. Intern Med. 2018 Jan 11;: Authors: Yoshizawa T, Ishikawa K, Nagasawa H, Takeuchi I, Jitsuiki K, Omori K, Ohsaka H, Yanagawa Y Abstract A 35-year-old man (height, 169 cm; body weight,240 kg; BMI, 84) visited the Department of Dermatology due to left leg pain and swelling. Focused enhanced computed tomography (CT) of the left leg ruled out complications of deep venous thrombosis. Surgical exploration of the left leg resulted in a diagnosis of necrotic soft tissue infection, but amputation was ruled out due...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Progressive Restrictive Ventilatory Impairment in Idiopathic Diffuse Pulmonary Ossification.
Authors: Matsuo H, Handa T, Tsuchiya M, Kubo T, Yoshizawa A, Nakayama Y, Shiga S, Hitomi T, Adachi S, Date H, Hirai T, Ichiyama S Abstract Diffuse pulmonary ossification (DPO) is a rare disease characterized by metaplastic bone formation in the lung. There are few reports with a long-term follow-up of this disease. We herein report a 47-year-old man diagnosed with idiopathic DPO at 30 years of age. The patient's vital capacity was normal until 36 years of age (3.39 L, 82.4% predicted), but it was severely decreased when he visited the hospital again at 47 years of age due to cough and dyspnea (1.98 L, 44.6% predict...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Constrictive Pericarditis as a Long-term Undetermined Etiology of Ascites and Edema.
We present the case of a 69-year-old woman with a 7-year history of leg edema and a 2-year history of ascites who was initially diagnosed with cryptogenic liver cirrhosis and was finally diagnosed with CP. PMID: 29321423 [PubMed - as supplied by publisher] (Source: Internal Medicine)
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

A Case of Anti-MuSK Antibody-positive Myasthenia Gravis Successfully Treated With Outpatient Periodic Weekly Blood Purification Therapy.
Authors: Deguchi K, Matsuzono K, Nakano Y, Kono S, Sato K, Deguchi S, Tanabe K, Hishikawa N, Ota Y, Yamashita T, Ohta K, Motomura M, Abe K Abstract A 37-year-old man with anti-muscle-specific tyrosine kinase (MuSK) antibody-positive myasthenia gravis (MG) presented with subacute progressive dysphagia and muscle weakness of the neck and bilateral upper extremities. Conventional immune-suppressive treatments and high-dose intravenous immunoglobulin were ineffective. He then displayed repeated exacerbations and remissions over the course of two years, despite two to four sessions of plasma exchange (PE) every two mont...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Elevation of Plasmin- α2-plasmin Inhibitor Complexes in Patients with AL Amyloidosis.
Elevation of Plasmin-α2-plasmin Inhibitor Complexes in Patients with AL Amyloidosis. Intern Med. 2018 Jan 11;: Authors: Miyazaki K, Suzuki K PMID: 29321425 [PubMed - as supplied by publisher] (Source: Internal Medicine)
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Percutaneous Coronary Intervention for a Patient with Left Main Coronary Compression Syndrome.
Authors: Ikegami R, Ozaki K, Ozawa T, Hirono S, Ito M, Minamino T Abstract Left main coronary compression syndrome rarely occurs in patients with severe pulmonary hypertension. A 65-year-old woman with severe pulmonary hypertension due to an atrial septal defect suffered from angina on effort. Cardiac computed-tomography and coronary angiography revealed considerable stenosis of the left main coronary artery (LMA) caused by compression between the dilated main pulmonary artery trunk and the sinus of valsalva. Stenting of the LMA under intravascular ultrasound imaging was effective for the treatment of angina. We he...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Cardiac Sarcoidosis Concomitant with Large-vessel Aortitis Detected by 18F-fluorodeoxyglucose Positron Emission Tomography.
Authors: Higuchi Y, Kimoto Y, Tanoue R, Tokunou T, Tomonari K, Maeda T, Horiuchi T Abstract We herein report a case of concurrent cardiac sarcoidosis and large-vessel aortitis detected by 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) and followed up during immunosuppressive therapy. After high-dose prednisolone administration (1 mg/kg), serial FDG-PET showed that almost all of the abnormal FDG uptake in the heart and extracardiac region, including the abdominal to bilateral iliac arteries, had been disappeared. During the tapering of prednisolone, additive methotrexate therapy was needed to treat th...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Synchronous Occurrence of Mycosis Fungoides, Diffuse Large B cell Lymphoma and Acute Myeloid Leukemia: A Report of Two Cases.
Authors: Miyatake J, Inoue H, Serizawa K, Morita Y, Espinoza JL, Tanaka H, Shimada T, Tatsumi Y, Ashida T, Matsumura I Abstract Patients with mycosis fungoides (MF), the most common subtype of primary cutaneous T-cell lymphoma, have an increased risk of developing secondary malignancies. We herein report two rare cases of MF concurring with diffuse large B cell lymphoma (B lymphoid lineage) and acute myeloid leukemia (myeloid lineage) in two otherwise healthy elderly patients. Potential etiologic factors, including the impact of the therapy-associated inflammatory response on the development of secondary tumors in ...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Early Combination Therapy with Corticosteroid and Nucleoside Analogue Induces Rapid Resolution of Inflammation in Acute Liver Failure Due to Transient Hepatitis B Virus Infection.
We examined the clinical and biochemical features of 19 patients with HBV-ALF who were treated in the early stage of the disease between 2000 and 2015. Results Fourteen patients received CS and NA (CS + NA group) and 5 received NA monotherapy (NA group). Eleven patients (58%) survived and 8 (42%) died. The survival rates in the CS + NA and NA groups were 64% and 40%, respectively (p=0.60). The mean ALT levels declined significantly at week 2 in both groups. The mean PT activities improved significantly at weeks 1 and 2 in the CS + NA group (p
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

New-onset Takayasu's Arteritis as Acute Myocardial Infarction.
Authors: Ishiyama Y, Eguchi K, Yokota K, Ikemoto T, Kario K Abstract We herein report the case of a 25-year-old Japanese woman with left-main-trunk acute myocardial infarction (LMT-AMI). She had cardiogenic shock, so emergency percutaneous intervention was performed. Intravascular ultrasound of LMT-AMI showed that the three-layered structure of the intima, tunica media, and adventitia was not clearly visible, and the vessel was concentrically thickened; unstable plaque and calcification were not seen. AMI is rarely seen in young women, but Takayasu's arteritis is one major cause. If a young woman complaining of typ...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Self-reported Slower Eating is Associated with a Lower Salt Intake: A Population-based Cross-sectional Study.
Conclusion Our results suggest that reducing eating rates may be an effective strategy for reducing dietary salt intake as well as preventing obesity. PMID: 29321431 [PubMed - as supplied by publisher] (Source: Internal Medicine)
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Acute-onset Autoimmune Hepatitis in a Young Woman with Type 1 Diabetes Mellitus.
Authors: Takai S, Inoue J, Kogure T, Kakazu E, Ninomiya M, Iwata T, Umetsu T, Nakamura T, Sano A, Shimosegawa T Abstract Autoimmune hepatitis (AIH) and type 1 diabetes mellitus (T1DM) are thought to be induced by autoimmunity, but their coexistence has rarely been reported. We herein report a case in which a patient with T1DM developed acute-onset AIH. A 26-year-old woman, who had been diagnosed with T1DM in childhood, was transferred to our hospital because of acute liver failure of unknown etiology. The administration of corticosteroids including steroid pulse therapy was effective. Based on the histological find...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

A Case of CV2/CRMP5-antibody-related Paraneoplastic Optic Neuropathy Associated with Small-cell Lung Cancer.
Authors: Nakajima M, Uchibori A, Ogawa Y, Miyazaki T, Ichikawa Y, Kaneko K, Takahashi T, Nakashima I, Shiraishi H, Motomura M, Chiba A Abstract A 61-year-old woman who had smoked for 40 years developed subacute dizziness, ataxic gait, opsoclonus, and right visual impairment. She had right optic disc swelling and optic nerve gadolinium enhancement on magnetic resonance imaging. She had small-cell lung cancer (SCLC), with CV2/collapsin response mediator protein (CRMP) 5 and HuD antibodies in her serum and cerebrospinal fluid. She was diagnosed with paraneoplastic optic neuropathy (PON) accompanied by paraneoplastic o...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Tricuspid and Mitral Valve Regurgitation with Bi-fascicular Block Following a Horse Kick.
Authors: Kokubun T, Oikawa M, Ichijo Y, Matsumoto Y, Yokokawa T, Nakazato K, Sato Y, Takase S, Shinjo H, Yokoyama H, Suzuki H, Saitoh SI, Takeishi Y Abstract A 40-year-old man was transferred to our hospital following an isolated horse kick injury to the anterior chest wall. The case showed bi-fascicular block, severe tricuspid valve regurgitation due to ruptured chordae tendineae of the anterior leaflet, moderate mitral valve regurgitation due to prolapse of mitral anterior leaflet, and hypokinetic motion of the inferior septal wall. Both tricuspid and mitral insufficiency were completely repaired by a surgical op...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Chronic Expanding Hematoma on the Chest Wall after Mastectomy.
Authors: Ookura R, Sakai G, Nishida N PMID: 29321435 [PubMed - as supplied by publisher] (Source: Internal Medicine)
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Necrotizing Sarcoid Granulomatosis with Natural Resolution after a Surgical Lung Biopsy.
Authors: Shibata T, Takahashi K, Uchida M, Yamasaki F, Kawashima M, Sueoka-Aragane N Abstract Necrotizing sarcoid granulomatosis (NSG) is a rare disease that is diagnosed based on pathological findings. We herein report the case of a 27-year-old man who had multiple nodular shadows in bilateral lung fields on chest radiography and elevated levels of C-reactive protein (CRP). The pathological evaluation of a lung biopsy specimen showed the infiltration of lymphocytes, granulomas with necrosis and granulomatous angiitis. He was therefore diagnosed with NSG. He has been followed without treatment, as his fever and CRP...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Esophageal Granular Cell Tumors Can Be Differentiated from Leiomyomas Using Endoscopic Ultrasonography.
Conclusion The echogenicity of granular cell tumors was similar to that of the submucosal layer, and it was significantly higher than that of leiomyomas. Endoscopic ultrasonography images facilitate the accurate identification of esophageal granular cell tumors. PMID: 29321437 [PubMed - as supplied by publisher] (Source: Internal Medicine)
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Vogt-Koyanagi-Harada Disease Associated with Influenza A Virus Infection: A Case Report.
Authors: Yoshino N, Kawamura A, Ishii A, Yoshida K, Watanabe T, Yamashita T, Fukuchi T, Toyoda F, Kakehashi A, Sugawara H Abstract We herein report a case of a 31-year-old Japanese man who simultaneously had a positive influenza A virus antigen test result and Vogt-Koyanagi-Harada disease (VKHD), demonstrated by both diffuse multiple early hyperfluorescent points on fluorescein fundus photography and serous retinal detachments on optical coherence tomography. He had meningitis. It was difficult to determine whether the main cause of meningitis was influenza A or VKHD. After initial treatment with peramivir for infl...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

The Association of Bite Instability and Comorbidities in Elderly People.
Conclusion Bite instability was independently associated with a decreased prevalence of hypertension or increased prevalence of diabetes mellitus and low levels of instrumental ADL in the elderly. PMID: 29321439 [PubMed - as supplied by publisher] (Source: Internal Medicine)
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

An Overview of Kidney Disease Following Hematopoietic Cell Transplantation.
Authors: Ando M Abstract Hematopoietic stem cell transplantation (SCT) recipients are exposed to a large amount of anti-cancer drugs, immunosuppressors, and irradiation during the peri-SCT period. Thus, they have to overcome serious adverse events related to unavoidable but toxic procedures, including organ disorders. In particular, acute kidney injury (AKI) is one of the most critical complications, because it influences the mortality of patients. A few patients who survive AKI may develop nephrotic syndrome, and precedent AKI is also closely associated with chronic and progressive loss of the renal function in po...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Diabetes Mellitus Prevents an Improvement in the Serum Albumin Level During Interferon-free Sofosbuvir-based Therapy for Chronic Hepatitis C Patients: A Multi-institutional Joint Study.
Conclusion Interferon-free SOF-based therapy significantly improved the serum albumin in the low-albumin group patients with chronic HCV infection. However, the improvement in the serum albumin level was significantly lower in the diabetic patients than in the non-diabetic patients. PMID: 29321441 [PubMed - as supplied by publisher] (Source: Internal Medicine)
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Acquired von Willebrand Syndrome Due to Aortic Valve Stenosis in a Case with Antiphospholipid Antibody.
Authors: Tanaka H, Nagai Y, Kuwabara C, Shimizu R, Umeki A, Yamamoto T Abstract Acquired von Willebrand syndrome (AVWS) is a bleeding disorder caused by an acquired deficiency of von Willebrand factor (vWF). Some patients with AVWS show a low bleeding tendency and are diagnosed by the presence of a mild prolongation of activated partial thromboplastin time (APTT) preoperatively. Another cause of APTT prolongation is the presence of antiphospholipid antibody (aPL). We experienced a case of AVWS due to aortic valve stenosis in a patient with aPL in whom aortic valve replacement surgery was successful with vWF replace...
Source: Internal Medicine - January 13, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Prolonged Dry Cough without Pulmonary Changes on Radiological Imaging.
Authors: Kondo T, Ohira Y, Uehara T, Noda K, Tsukamoto T, Ikusaka M Abstract A 16-year-old boy who was a non-smoker presented with a prolonged severe dry cough and malaise of 3 months in duration. Despite an increase in the patient's inflammatory marker levels, no respiratory lesions were radiologically or serologically detected. We suspected that the cough reflex pathway had been stimulated by large vessel vasculitis (a non-respiratory inflammatory condition) and diagnosed the patient with Takayasu arteritis. While inflammation of either the ascending pharyngeal or pulmonary artery have been reported to cause coug...
Source: Internal Medicine - December 28, 2017 Category: Internal Medicine Tags: Intern Med Source Type: research

Racemose Hemangioma of the Bronchial Artery.
Authors: Osawa H, Okauchi S, Satoh H PMID: 29279467 [PubMed - as supplied by publisher] (Source: Internal Medicine)
Source: Internal Medicine - December 28, 2017 Category: Internal Medicine Tags: Intern Med Source Type: research

Extending Carotid Artery Thrombus Associated with Thrombocytosis.
Authors: Kato Y, Nagamine Y, Hayashi T, Takao M PMID: 29279468 [PubMed - as supplied by publisher] (Source: Internal Medicine)
Source: Internal Medicine - December 28, 2017 Category: Internal Medicine Tags: Intern Med Source Type: research

A Giant Gastrointestinal Stromal Tumor with Cystic Morphology.
Authors: Harada K, Matsueda K, Toyokawa T PMID: 29279469 [PubMed - as supplied by publisher] (Source: Internal Medicine)
Source: Internal Medicine - December 28, 2017 Category: Internal Medicine Tags: Intern Med Source Type: research

Glycogen Hepatopathy: An Under-recognized Hepatic Complication of Uncontrolled Type 1 Diabetes Mellitus.
Authors: Sumida Y, Yoneda M PMID: 29279470 [PubMed - as supplied by publisher] (Source: Internal Medicine)
Source: Internal Medicine - December 28, 2017 Category: Internal Medicine Tags: Intern Med Source Type: research

Extracardiac Tumor From Duodenal Primary Gastrointestinal Stromal Tumor.
Authors: Miyazaki S, Ogimoto A, Matsukage S, Ohshima K PMID: 29279471 [PubMed - as supplied by publisher] (Source: Internal Medicine)
Source: Internal Medicine - December 28, 2017 Category: Internal Medicine Tags: Intern Med Source Type: research

Infective Endarteritis due to Staphylococcus capitis.
Authors: Yamamoto K, Ohmagari N PMID: 29279472 [PubMed - as supplied by publisher] (Source: Internal Medicine)
Source: Internal Medicine - December 28, 2017 Category: Internal Medicine Tags: Intern Med Source Type: research

False Elevation of the Blood Tacrolimus Concentration, as Assessed by an Affinity Column-mediated Immunoassay (ACMIA), Led to Acute T Cell-Mediated Rejection after Kidney Transplantation: A Case Report.
We report the case of a 25-year-old man who underwent kidney transplantation whose tacrolimus concentrations, as measured by an affinity column-mediated immunoassay, were falsely elevated. As we reduced the dose of tacrolimus, the recipient developed T cell-mediated rejection. Using the same blood samples, an enzyme-multiplied immunoassay technique showed that the patient's levels of tacrolimus were extremely low. A further examination indicated that the false increase in the tacrolimus concentration was likely due to an unknown interfering substance. We administered methylprednisolone and antithymocyte-globulin. The patie...
Source: Internal Medicine - December 28, 2017 Category: Internal Medicine Tags: Intern Med Source Type: research

Invasive Candida Infection with Ureteral Obstruction.
Authors: Tomoda Y, Kihara Y, Kouzuma R, Tanaka K PMID: 29279474 [PubMed - as supplied by publisher] (Source: Internal Medicine)
Source: Internal Medicine - December 28, 2017 Category: Internal Medicine Tags: Intern Med Source Type: research