Circular RNA hsa_circ_0094976 modulates GPR155 to inhibit gastric adenocarcinoma malignant characteristics by targeting miR-223-3p
CONCLUSION: We disclosed that circ_0094976 could act as a sponge of miR-223-3p to regulate the expression of GPR155, and further restrain the development of GA, which may provide new insight into the therapy of GA.PMID:38678850 | DOI:10.1016/j.prp.2024.155325 (Source: Cell Research)
Source: Cell Research - April 28, 2024 Category: Cytology Authors: Li Liu Xuefeng Li Lingli Song Yuhan Yang Binxian Li Source Type: research
Biological functions of Circular RNA_LARP4/ Upstream frameshift 1 in development of gastric cancer
This study aimed to identify the role of circular RNA_LARP4 in GC. We performed real-time quantitative polymerase chain reaction (RT-qPCR) in 46 paired GC patients and GC cell lines to detect the expression of circular RNA_LARP4. Moreover, the role of circular RNA_LARP4 in GC proliferation was identified through proliferation assay and colony formation assay, while the role of circular RNA_LARP4 in GC metastasis was measured through scratch wound assay and transwell assay. Furthermore, the potential targets of circular RNA_LARP4 were predicted through bioinformatics methods and further identified by western blot assay and ...
Source: Mol Biol Cell - April 28, 2024 Category: Molecular Biology Authors: Jing Zhang Yaqing Yang Xuzheng Song Kuo Xing Yu Chen Source Type: research
Prognostic factors and significance of postoperative adjuvant chemotherapy in patients with advanced gastric cancer undergoing neoadjuvant chemotherapy followed by gastrectomy
ConclusionsypN status and postoperative adjuvant chemotherapy were independent prognostic factors in gastric cancer patients who underwent NAC followed by curative gastrectomy. It is important to maintain the patient ’s condition during NAC and the perioperative period so that they can receive postoperative adjuvant chemotherapy. (Source: Surgery Today)
Source: Surgery Today - April 28, 2024 Category: Surgery Source Type: research
Cancers, Vol. 16, Pages 1721: Textbook Neoadjuvant Outcome & mdash;Novel Composite Measure of Oncological Outcomes among Gastric Cancer Patients Undergoing Multimodal Treatment
Cancers, Vol. 16, Pages 1721: Textbook Neoadjuvant Outcome—Novel Composite Measure of Oncological Outcomes among Gastric Cancer Patients Undergoing Multimodal Treatment
Cancers doi: 10.3390/cancers16091721
Authors:
Zuzanna Pelc
Katarzyna Sędłak
Magdalena Leśniewska
Katarzyna Mielniczek
Katarzyna Chawrylak
Magdalena Skórzewska
Tomasz Ciszewski
Joanna Czechowska
Agata Kiszczyńska
Bas P. L. Wijnhoven
Johanna W. Van Van Sandick
Ines Gockel
Suzanne S. Gisbertz
Guillaume Piessen
Clarisse Eveno
Maria Bencivenga
Giovanni De Manzoni
Gian Luca Baiocchi
Paolo Morgagni
Riccardo ...
Source: Cancers - April 28, 2024 Category: Cancer & Oncology Authors: Zuzanna Pelc Katarzyna S ędłak Magdalena Le śniewska Katarzyna Mielniczek Katarzyna Chawrylak Magdalena Sk órzewska Tomasz Ciszewski Joanna Czechowska Agata Kiszczy ńska Bas P. L. Wijnhoven Johanna W. Van Van Sandick Ines Gockel Suzanne S. Gisbertz G Tags: Review Source Type: research
Beyond Tumors: Gastric Syphilis Emulating a Gastric Neoplasia
We present the case of a 35-year-old male with a first-degree family history of gastric cancer (his father was diagnosed at the age of 45), who was presumed to have gastric cancer himself when evaluating the features of his upper endoscopy performed after hematemesis. Surprisingly, no cancer cells were found in the biopsies. Thanks to a different diagnostic suspicion subsequent to performing a full clinical history, a more favorable diagnosis was reached: gastric syphilis.PMID:38674276 | PMC:PMC11052094 | DOI:10.3390/medicina60040629 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Claudia Guerrero Mu ñoz Andres Casta ñeda Agredo Maria Jose Romero Valle Andr és Mauricio Silva Silva Marta Le ón Del Campo Claudia Azpirtarte S ánchez Marta Dom ínguez Fraga Manuel Vicente Mil án Pilo Benjamin Arturo Polo Lorduy Agustina Gonz ále Source Type: research
Beyond Tumors: Gastric Syphilis Emulating a Gastric Neoplasia
We present the case of a 35-year-old male with a first-degree family history of gastric cancer (his father was diagnosed at the age of 45), who was presumed to have gastric cancer himself when evaluating the features of his upper endoscopy performed after hematemesis. Surprisingly, no cancer cells were found in the biopsies. Thanks to a different diagnostic suspicion subsequent to performing a full clinical history, a more favorable diagnosis was reached: gastric syphilis.PMID:38674276 | PMC:PMC11052094 | DOI:10.3390/medicina60040629 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Claudia Guerrero Mu ñoz Andres Casta ñeda Agredo Maria Jose Romero Valle Andr és Mauricio Silva Silva Marta Le ón Del Campo Claudia Azpirtarte S ánchez Marta Dom ínguez Fraga Manuel Vicente Mil án Pilo Benjamin Arturo Polo Lorduy Agustina Gonz ále Source Type: research
Beyond Tumors: Gastric Syphilis Emulating a Gastric Neoplasia
We present the case of a 35-year-old male with a first-degree family history of gastric cancer (his father was diagnosed at the age of 45), who was presumed to have gastric cancer himself when evaluating the features of his upper endoscopy performed after hematemesis. Surprisingly, no cancer cells were found in the biopsies. Thanks to a different diagnostic suspicion subsequent to performing a full clinical history, a more favorable diagnosis was reached: gastric syphilis.PMID:38674276 | PMC:PMC11052094 | DOI:10.3390/medicina60040629 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Claudia Guerrero Mu ñoz Andres Casta ñeda Agredo Maria Jose Romero Valle Andr és Mauricio Silva Silva Marta Le ón Del Campo Claudia Azpirtarte S ánchez Marta Dom ínguez Fraga Manuel Vicente Mil án Pilo Benjamin Arturo Polo Lorduy Agustina Gonz ále Source Type: research
Beyond Tumors: Gastric Syphilis Emulating a Gastric Neoplasia
We present the case of a 35-year-old male with a first-degree family history of gastric cancer (his father was diagnosed at the age of 45), who was presumed to have gastric cancer himself when evaluating the features of his upper endoscopy performed after hematemesis. Surprisingly, no cancer cells were found in the biopsies. Thanks to a different diagnostic suspicion subsequent to performing a full clinical history, a more favorable diagnosis was reached: gastric syphilis.PMID:38674276 | PMC:PMC11052094 | DOI:10.3390/medicina60040629 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Claudia Guerrero Mu ñoz Andres Casta ñeda Agredo Maria Jose Romero Valle Andr és Mauricio Silva Silva Marta Le ón Del Campo Claudia Azpirtarte S ánchez Marta Dom ínguez Fraga Manuel Vicente Mil án Pilo Benjamin Arturo Polo Lorduy Agustina Gonz ále Source Type: research
Beyond Tumors: Gastric Syphilis Emulating a Gastric Neoplasia
We present the case of a 35-year-old male with a first-degree family history of gastric cancer (his father was diagnosed at the age of 45), who was presumed to have gastric cancer himself when evaluating the features of his upper endoscopy performed after hematemesis. Surprisingly, no cancer cells were found in the biopsies. Thanks to a different diagnostic suspicion subsequent to performing a full clinical history, a more favorable diagnosis was reached: gastric syphilis.PMID:38674276 | PMC:PMC11052094 | DOI:10.3390/medicina60040629 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Claudia Guerrero Mu ñoz Andres Casta ñeda Agredo Maria Jose Romero Valle Andr és Mauricio Silva Silva Marta Le ón Del Campo Claudia Azpirtarte S ánchez Marta Dom ínguez Fraga Manuel Vicente Mil án Pilo Benjamin Arturo Polo Lorduy Agustina Gonz ále Source Type: research
Beyond Tumors: Gastric Syphilis Emulating a Gastric Neoplasia
We present the case of a 35-year-old male with a first-degree family history of gastric cancer (his father was diagnosed at the age of 45), who was presumed to have gastric cancer himself when evaluating the features of his upper endoscopy performed after hematemesis. Surprisingly, no cancer cells were found in the biopsies. Thanks to a different diagnostic suspicion subsequent to performing a full clinical history, a more favorable diagnosis was reached: gastric syphilis.PMID:38674276 | PMC:PMC11052094 | DOI:10.3390/medicina60040629 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Claudia Guerrero Mu ñoz Andres Casta ñeda Agredo Maria Jose Romero Valle Andr és Mauricio Silva Silva Marta Le ón Del Campo Claudia Azpirtarte S ánchez Marta Dom ínguez Fraga Manuel Vicente Mil án Pilo Benjamin Arturo Polo Lorduy Agustina Gonz ále Source Type: research
Revolutionizing Gastric Cancer Prevention: Novel Insights on Gastric Mucosal Inflammation-Cancer Transformation and Chinese Medicine
AbstractThe progression from gastric mucosal inflammation to cancer signifies a pivotal event in the trajectory of gastric cancer (GC) development. Chinese medicine (CM) exhibits unique advantages and holds significant promise in inhibiting carcinogenesis of the gastric mucosa. This review intricately examines the critical pathological events during the transition from gastric mucosal inflammation-cancer transformation (GMICT), with a particular focus on pathological evolution mechanisms of spasmolytic polypeptide-expressing metaplasia (SPEM). Moreover, it investigates the pioneering applications and advancements of CM in ...
Source: Chinese Journal of Integrative Medicine - April 27, 2024 Category: Internal Medicine Source Type: research
Cancers, Vol. 16, Pages 1707: Utility of Clinical Next Generation Sequencing Tests in KIT/PDGFRA/SDH Wild-Type Gastrointestinal Stromal Tumors
Conclusions: Triple-negative GISTs comprise a diverse cohort with different driver mutations. Compared to KIT/PDGFRA-mutant GIST, limited benefit was observed with imatinib in triple-negative GIST. In depth molecular profiling can be helpful in identifying driver mutations and guiding therapy. (Source: Cancers)
Source: Cancers - April 27, 2024 Category: Cancer & Oncology Authors: Ryan A. Denu Cissimol P. Joseph Elizabeth S. Urquiola Precious S. Byrd Richard K. Yang Ravin Ratan Maria Alejandra Zarzour Anthony P. Conley Dejka M. Araujo Vinod Ravi Elise F. Nassif Haddad Michael S. Nakazawa Shreyaskumar Patel Wei-Lien Wang Alexander J Tags: Article Source Type: research
Pathological Complete Response Achieved with XELOX Chemotherapy, HIPEC, and Anti-PD-1 Immunotherapy in Stage IV Gastric Adenocarcinoma with Peritoneal Metastasis: A Case Report and Review of the Literature
ConclusionThe conversion therapy protocol combined with HIPEC, XELOX chemotherapy, and anti-PD-1 therapy and our scientific, accurate, full-course management strategy may be propagable for potentially curing patients with advanced GC with PM. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - April 27, 2024 Category: Cancer & Oncology Source Type: research
Cancers, Vol. 16, Pages 1708: Prognosis and Treatment of Gastric Cancer: A 2024 Update
l Samasca
Due to the high death rate associated with gastric cancer, a great deal of research has been conducted on this disease. The goal of this paper was to start a trimestral review of 2024 for the year that had just started. The scientific literature from 1 January 2024 was chosen with consideration of the the guidelines of the European Society of Medical Oncology (ESMO), which are updated with new findings but not systematically reviewed annually. We used the search term “gastric cancer” to find the most current publications in the PubMed database related to the prognosis and treatment...
Source: Cancers - April 27, 2024 Category: Cancer & Oncology Authors: Claudia Burz Vlad Pop Ciprian Silaghi Iulia Lupan Gabriel Samasca Tags: Review Source Type: research
Cancers, Vol. 16, Pages 1706: Dissecting the Puzzling Roles of FAM46C: A Multifaceted Pan-Cancer Tumour Suppressor with Increasing Clinical Relevance
Manfrini
FAM46C is a well-established tumour suppressor with a role that is not completely defined or universally accepted. Although FAM46C expression is down-modulated in several tumours, significant mutations in the FAM46C gene are only found in multiple myeloma (MM). Consequently, its tumour suppressor activity has primarily been studied in the MM context. However, emerging evidence suggests that FAM46C is involved also in other cancer types, namely colorectal, prostate and gastric cancer and squamous cell and hepatocellular carcinoma, where FAM46C expression was found to be significantly reduced in tumoural versus...
Source: Cancers - April 27, 2024 Category: Cancer & Oncology Authors: Giancarlo Lai Federica De Grossi Ilaria Catusi Elisa Pesce Nicola Manfrini Tags: Review Source Type: research
