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Neuroprotective effects of Moringa oleifera : Bio-guided GC-MS identification of active compounds in diabetic neuropathic pain model
ConclusionsThe observed insulin secretagogue, alpha-glucosidase inhibition, hypoglycemic and antioxidant potentials might be responsible for MO and BSL antinociception and neuroprotective mechanism. MO and BSL have shown good glycemic-control and powerful neuroprotective properties which might serve as potential lead-compounds for further analysis. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - December 12, 2017 Category: Internal Medicine Source Type: research

Electroacupuncture stimulation of language-implicated acupoint Tongli (HT 5) in healthy subjects: An fMRI evaluation study
AbstractObjectiveTo explore brain activations associated with electroacupuncture simulation at Tongli (HT 5) and its comparison with brain activations during picture-naming task.MethodsTwenty healthy subjects were enrolled in this study. Half of them received electroacupuncture stimulation at HT 5 (ACUP group) and the other half of them received stimulation at a nonmeridian sham acupoint (SHAM group). All subjects performed picture-naming task. Each subject finished two runs of functional magnetic resonance imaging examinations in one session and picture-naming task was performed before electroacupuncture stimulation. Subj...
Source: Chinese Journal of Integrative Medicine - December 11, 2017 Category: Internal Medicine Source Type: research

Salvianolate reduces glucose metabolism disorders in dimethylnitrosamine-induced cirrhotic rats
AbstractObjectiveTo evaluate the preventive effect of salvianolate (Sal B) on glucose metabolism disorders of dimethylnitrosamine (DMN)-induced cirrhotic rats.MethodsFifty-five Wistar rats were randomly divided into a control group (n=10) and a cirrhotic group (n=45) according to a random number table. Liver cirrhosis was induced by intraperitoneal administration of DMN. The cirrhotic rats were divided into model, Sal B and metformin groups (n=15), respectively. Rats in the model group were given saline, two treatment groups were given Sal B (50 mg/kg), metformin (150 mg/kg) respectively for 28 consecutive days, while rats...
Source: Chinese Journal of Integrative Medicine - December 5, 2017 Category: Internal Medicine Source Type: research

Moxibustion therapy in traditional Mongolian medicine
AbstractFrom the medical history of traditional Eastern Asian and Tibetan medicine, the origin and development of moxibustion seems to be closely related to Mongolia. To explore the current clinical practice of moxibustion in Mongolia, we visited a teaching hospital, the Traditional Medical Science, Technology and Production Corporation of Mongolia, in February 2014. Many types of moxibustion are found to be used, and various modalities and methods are practiced based on the principles of traditional Mongolian medicine. In particular, Mongolian drug moxibustion, which uses small butter-warmed bags packed with powdered arom...
Source: Chinese Journal of Integrative Medicine - December 5, 2017 Category: Internal Medicine Source Type: research

Improving the level and quality of ethics review in Chinese medicine and integrative medicine
AbstractThree features of ethics review in Chinese medicine (CM) and integrative medicine (IM) were put forward in this paper. It is consistent with the principles of ethical review in Western medicine; it has to be compliant with the laws of CM and IM; emphasis should be laid on the review of clinical practice facts and experience. Three problems were pointed out. The characteristics of CM and IM are not distinctive enough, operation procedures need to be refined and effectiveness remains to be improved. Based on the mentioned above, seven measures were proposed to improve the level and quality of ethics review in CM and ...
Source: Chinese Journal of Integrative Medicine - December 5, 2017 Category: Internal Medicine Source Type: research

Systematic reviews/meta-analyses of integrative medicine in Chinese need regulation and monitoring urgently and some suggestions for its solutions
AbstractWith the introduction and development of evidence-based medicine in China, it has been spread rapidly in the area of integrative medicine (IM) and has become a new unique discipline. During almost 20 years, as one of the most important parts of evidence-based IM, systematic review (SR)/meta-analysis (MA) of IM have shown a good development momentum in the aspects of quantity, depth, breadth and influence, but also face the harsh situation of the uncontrolled quantity and quality, especially for SRs in Chinese. Therefore, how to supervise and standardize this area effectively becomes a problem to be solved. Based on...
Source: Chinese Journal of Integrative Medicine - December 5, 2017 Category: Internal Medicine Source Type: research

Protective effects of traditional Tibetan medicine Zuo-Mu-A Decoction ( 佐木阿汤) on the blood parameters and myocardium of high altitude polycythemia model rats
AbstractObjectiveTo explore the protective effects of Tibetan medicine Zuo-Mu-A Decoction ( 佐木阿汤, ZMAD) on the blood parameters and myocardium of high altitude polycythemia (HAPC) model rats.MethodsForty male Wistar rats were randomly divided into 4 groups by a random number table, including the normal, model,Rhodiola rosea L. (RRL) and ZMAD groups (10 in each group). Every group was raised in Lhasa to create a HAPC model except the normal group. After modeling, rats in the RRL and the ZMAD groups were administered intragastrically with RRL (20 mL/kg) and ZMAD (7.5 mL/kg) once a day for 2 months, respectively; for ...
Source: Chinese Journal of Integrative Medicine - December 1, 2017 Category: Internal Medicine Source Type: research

Is acupuncture actually not effective for polycystic ovary syndrome?
AbstractIn recent years, acupuncture has been applied to treat more and more patients suffering from polycystic ovary syndrome (PCOS). On June 27, 2017 a paper titled “Effect of acupuncture and clomiphene in Chinese women with polycystic ovary syndrome: a randomized clinical trial” was published inJournal of the American Medical Association (JAMA). The results did not support acupuncture as an effective therapy for improving the live births in PCOS. The aim of this article was to analyze the therapeutic regimen and design of the clinical trial. The primary outcome and the conclusion of the paper were discussed ...
Source: Chinese Journal of Integrative Medicine - December 1, 2017 Category: Internal Medicine Source Type: research

Reporting characteristics of case reports of acupuncture therapy with CARE guidelines
ConclusionsThe reporting quality of case reports of acupuncture therapy is rather low. The reason might be a lack of awareness among authors and the poor dissemination of information regarding CARE guidelines in China. More evaluation studies are needed to promote and improve adherence to CARE guidelines. Moreover, an extended version of CARE guidelines should be developed for cases reports of special interventions such as acupuncture or adverse events caused by interventions. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - November 28, 2017 Category: Internal Medicine Source Type: research

Modified Xiaochaihu decoction ( 加味小柴胡汤) promotes collagen degradation and inhibits pancreatic fibrosis in chronic pancreatitis rats
AbstractObjectiveTo investigate the effect of Modified Xiaochaihu Decoction (MXD, 加味小柴胡汤) on collagen degradation in rats with chronic pancreatitis (CP).MethodsRats were injected dibutyltin dichloride (DBTC, 7 mg/kg of body weight) into the right caudal vein to induce CP model. Thirty heallhy male Wistar rats were randomly divided into three groups by a random number table: the control, the model and the treatment groups. Rats of treatment group were administered MXD (10 g/kg of body weight) orally once daily starting from the day post-model establishment. Pancreatic tissues were harvested after 28-day feeding ...
Source: Chinese Journal of Integrative Medicine - November 28, 2017 Category: Internal Medicine Source Type: research

Sodium Tanshinone II A sulfonate injection as adjuvant treatment for unstable angina pectoris: A meta-analysis of 17 randomized controlled trials
AbstractObjectiveTo systematically evaluate the effectiveness and safety of Sodium Tanshinone II A Sulfonate Injection (STS) as one adjuvant therapy for treating unstable angina pectoris (UAP).MethodsRandomized controlled trials (RCTs) of UAP treated by STS were searched in the China National Knowledge Infrastructure Database (CNKI), VIP Database for Chinese Technical Periodicals (VIP), Wanfang Database, the Chinese Biomedical Literature Database (CBM), Web of Science, the Cochrane Library, Embase, and PubMed, which from inception to January, 2016. The Cochrane Risk Assessment Tool was used to evaluate the methodological q...
Source: Chinese Journal of Integrative Medicine - November 28, 2017 Category: Internal Medicine Source Type: research

Clinical study on Yishen Qufeng Shengshi Recipe ( 益肾祛风胜湿方) for glomerular proteinuria patients: A randomized controlled trial
AbstractObjectiveTo explore the therapeutic effect of Yishen Qufeng Shengshi Recipe ( 益肾祛风胜湿方, YQSR) in patients with glomerular proteinuria.MethodsA total of 145 patients with glomerular proteinuria were selected and randomly assigned to the treatment group (108 cases) and the control group (37 cases) according to a random number table in a ratio of 3:1. All patients received conventional and symptomatic treatment. In addition, patients in the treatment and control groups were given YQSR (200 mL, twice per day, orally) and losartan (50 mg/d orally), respectively for 6 months. The 24-h urine protein quantity,...
Source: Chinese Journal of Integrative Medicine - November 17, 2017 Category: Internal Medicine Source Type: research

Radial pulse and electrocardiography modulation by mild thermal stresses applied to feet: An exploratory study with randomized, crossover design
AbstractObjectiveTo investigate the changes in radial pulse induced by thermal stresses (TSs).MethodsSixty subjects were enrolled. Using an open-label, 2 ×2 crossover randomization design, both feet of each subject were immersed in 15 °C water for cold stress (CS) and in 40 °C water for heat stress (HS) for 5 min each. Radial pulse, respiration and electrocardiogram (ECG) signals were recorded before, during and immediately after the TSs.ResultsThe analysis of heart rate variability revealed that CS increased the low-frequency (LF) and high-frequency (HF) components (P
Source: Chinese Journal of Integrative Medicine - November 17, 2017 Category: Internal Medicine Source Type: research

Effects of Ligustrazine on Airway Inflammation in A Mouse Model of Neutrophilic Asthma
AbstractObjectiveTo investigate the effects of ligustrazine (LTZ) on airway inflammation in a mouse model of neutrophilic asthma (NA).MethodsForty healthy C57BL/6 female mice were randomly divided into 4 groups using a random number table, including the normal control, NA, LTZ and dexamethasone (DXM) groups, with 10 rats in each group. The NA mice model was established by the method of ovalbumin combined with lipopolysaccharide sensitization. At 0.5 h before each challenge, LTZ and DXM groups were intraperitoneally injected with LTZ (80 mg/kg) or DXM (0.5 mg/kg) for 14 d, respectively, while the other two groups were given...
Source: Chinese Journal of Integrative Medicine - October 30, 2017 Category: Internal Medicine Source Type: research

Expression of PYCARD Gene Transcript Variant mRNA in Peripheral Blood Mononuclear Cells of Primary Gout Patients with Different Chinese Medicine Syndromes
AbstractObjectiveTo study the expression level and role of apoptosis-associated speck-like protein containing a caspase recruitment domain (PYCARD) gene transcript variant mRNA in peripheral blood mononuclear cells (PBMCs) of primary gout (PG) patients with different Chinese medicine (CM) syndromes.MethodsThe expressions of PYCARD gene transcript variant mRNA and interleukin-1 β (IL-1β) mRNA in PBMCs were investigated in 96 PG patients with acute phase (APPG, 44 cases) and non-acute phase (NAPPG, 52 cases) and 30 healthy controls (HCs) by reverse transcription-polymerase chain reaction (PCR) and/or realtime quant...
Source: Chinese Journal of Integrative Medicine - October 30, 2017 Category: Internal Medicine Source Type: research

Acupuncture treatment for idiopathic trigeminal neuralgia: A longitudinal case-control double blinded study
AbstractObjectiveTo evaluate the treatment effect of acupuncture on patients with idiopathic trigeminal neuralgia (ITN) by case-control longitudinal blinded study.MethodsSixty ITN patients and 30 healthy subjects were included. The ITN patients were randomly assigned to acupuncture group (15 cases), sham-acupuncture group (15 cases) and carbamazepine group (30 cases), respectively. Clinical orofacial evaluation (including pain intensity and medication doses), research diagnostic criteria for temporomandibular disorders (RDC/TMD) and Helkimo indexes (for functional evaluation of the masticatory system), and quantitative sen...
Source: Chinese Journal of Integrative Medicine - October 27, 2017 Category: Internal Medicine Source Type: research

Patient feedback for acupuncture practice improvement: A survey from Mayo Clinic
ConclusionsWe used patient feedback to assess the acupuncture practice in a complementary and integrative medicine program. Most patients referred for the acupuncture consult appeared to be satisfied with the current level of practice. These findings were used to establish a quality improvement plan that may be implemented to improve patient satisfaction with the acupuncture practice. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - October 27, 2017 Category: Internal Medicine Source Type: research

Scutellaria barbata D. Don inhibits colorectal cancer growth via suppression of Wnt/ β-catenin signaling pathway
AbstractObjectiveTo investigate the effect of the ethanol extract of Scutellaria barbata D. Don (EESB) on colorectal cancer (CRC) growth and Wnt/ β-catenin signaling pathwayin vivo andin vitro.MethodsIn vivo experiment, CRC xenograft mouse model was constructed with injection of HT-29 cells. Following xenograft implantation, twenty mice were randomly divided into EESB-treated group (n=10) and control group (n=10) by a random number table, and were given with intra-gastric administration of 2 g/kg EESB or saline, 5 days a week for 16 days, respectively. At the end of experiment, tumors were removed and weighed by elect...
Source: Chinese Journal of Integrative Medicine - October 27, 2017 Category: Internal Medicine Source Type: research

Mast cell-derived exosomes at the stimulated acupoints activating the neuro-immune regulation
AbstractExosomes are cell-derived vesicles that take part in intercellular signaling. Research has shown that acupuncture is closely related to affecting the functions of the mast cells in the local region of the acupoint, and stimulating the afferent nerve. Mast cells have a connection with the conduction within the meridians, and play an important role in immuno-regulation. The ‘synapse-like’ connection between the mast cells and nerve endings is the basis for the exchange of information between these two tissues. Exosome mediates mast exchange of information between mast cells and the nerves, starting the pr...
Source: Chinese Journal of Integrative Medicine - October 27, 2017 Category: Internal Medicine Source Type: research

Nitric oxide signaling molecules in acupoints: Toward mechanisms of acupuncture
AbstractRecent clinical trial studies have demonstrated that the effects of acupuncture on pain improvement are small and no difference between acupoints and non-points. Whether acupuncture needles must be inserted in specific points depends on whether acupoint specificity exists that is still not resolved, and is now urgent. Previous anatomical studies have demonstrated that acupoints exist higher number of nerve fibers/trunks, blood vessels, hair follicles, and sweat glands as well as density of the gap junction. Recent evidence shows that nitric oxide (NO) level is elevated in the acupoints/ meridians and is associated ...
Source: Chinese Journal of Integrative Medicine - October 27, 2017 Category: Internal Medicine Source Type: research

Pivotal factors concerned in design of acupuncture clinical research: From two articles in JAMA
AbstractTwo randomized controlled trials of acupuncture concerning polycystic ovary syndrome (PCOS) and stress urinary incontinence (SUI) were published simultaneously in the 24th issue, 2017 ofThe Journal of the American Medical Association (JAMA). A trial involving PCOS indicated that active acupuncture did not increase live birth compared with sham acupuncture; meanwhile, another trial referring to SUI showed that electroacupuncture resulted in less urine leakage compared with sham electroacupuncture. With an eye to the negative and positive results of acupuncture, three pivotal factors should be contemplated: (1) prope...
Source: Chinese Journal of Integrative Medicine - October 27, 2017 Category: Internal Medicine Source Type: research

To be, or not to be: The calculated politics of acupuncture in JAMA
This article summarizes the acupuncturerelated clinical trials published over the last 20 years in JAMA, and addresses what seems to be a fundamental ambivalence in Western medical journals regarding the scientific validity of acupuncture/CM. As yet there has been no consensus on the role of acupuncture in healthcare in Western countries. This is hardly surprising, considering the conflicting evidence found in published studies. Skepticism regarding acupuncture/CM is largely grounded in the fact that an accurate model for assessing the true clinical effects of acupuncture has yet to be created. This article discusses some ...
Source: Chinese Journal of Integrative Medicine - October 27, 2017 Category: Internal Medicine Source Type: research

A summary and evaluation of current evidence for myocardial infarction with Chinese medicine
ConclusionsSufficient evidence supported the use of CM as an adjuvant to Western medicine for preventing and treating MI. The choice of drug use varies with disease stage and treatment objective. However, the quality of the evidence body remains to be enhanced. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - October 27, 2017 Category: Internal Medicine Source Type: research

Comparison on anticoagulation and antiplatelet aggregation effects of puerarin with heparin sodium and tirofiban hydrochloride: an in Vitro study
AbstractObjectiveTo detect the anticoagulation and antiplatelet effects of different concentrations of puerarin, heparin sodium and tirofiban hydrochloride on the blood samples of healthy volunteers by Sonoclot coagulation and platelet function analyzer.MethodsPeripheral blood samples were extracted from 20 healthy volunteers, followed by adding different concentrations of puerarin, heparin sodium and tirofiban hydrochloride. Samples were detected for activated clotting time (ACT), clot rate (CR) and platelet function (PF) by Sonoclot coagulation and platelet function analyzer instrument.ResultsFor puerarin and heparin sod...
Source: Chinese Journal of Integrative Medicine - October 25, 2017 Category: Internal Medicine Source Type: research

Different survival benefits of Chinese medicine for pancreatic cancer: How to choose?
ConclusionsIntervention of CM contributes to the different survival benefits for PC in different stages. Multimodality treatment might be a promising strategy for PC patients in early stage. While, in advanced stage, CM might be an alternative candidate for PC patients. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - October 24, 2017 Category: Internal Medicine Source Type: research

Effect of modified Wuzi Yanzong Pill ( 五子衍宗丸) on Tip60-mediated apoptosis in testis of male rats after microwave radiation
AbstractObjectiveTo investigate the effect of a modified Wuzi Yanzong Pill ( 五子衍宗丸, WZYZP) on the male rats' testis after microwave radiation, as well as its potential mechanism.MethodsForty-five male rats were randomly assigned to three groups: the control group, the radiation group, and the WZYZP group. The rats in the radiation group and WZYZP group were exposed to microwave radiation for 15 min once, while the rats in the control group were not exposed to any radiation. The rats in the WZYZP group were given a modified of WZYZP by gavage daily for 7 days. Apoptosis in the testis was evaluated using terminal-d...
Source: Chinese Journal of Integrative Medicine - October 24, 2017 Category: Internal Medicine Source Type: research

Characteristics of American scholars ’ research on Chinese medical classics and their contributions
AbstractChinese medical classics are important carriers for the inheritance, innovation and development of academic thoughts of Chinese medicine (CM), containing rich thoughts on diagnosis and treatment as well as therapeutic principles of CM. The international exchange of CM has a very long history. With the development of society, Western scholars in modern times are deepening their researches on Chinese medical classics. This would provide a new way for promoting CM in Western countries to investigate researches made by famed American scholars and their academic viewpoints. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - October 24, 2017 Category: Internal Medicine Source Type: research

Shenyi Capsule ( 参一胶囊) plus chemotherapy versus chemotherapy for non-small cell lung cancer: A systematic review of overlapping meta-analyses
ConclusionsBased on the best available evidence, treatment effect of SC plus chemotherapy was better than chemotherapy and did not increase side effects. Therefore, SC plus chemotherapy may be superior to chemotherapy for treating NSCLC. However, due to some limitations, SC plus chemotherapy should be cautiously considered, and further high-quality meta-analyses are needed. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - October 18, 2017 Category: Internal Medicine Source Type: research

Anti-human immunodeficiency virus-1 activities of pratensein and pratensein glycoside from Alhaji maurorum and its parasite Cuscuta kotchiana
ConclusionThe pratensein glycoside inhibits HIV-1 replication in host cells more than pratensein and both extracts are potent inhibitors of HIV-1 entry. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - October 18, 2017 Category: Internal Medicine Source Type: research

Pattern classification of enterovirus 71-associated hand, foot, and mouth disease in chinese medicine: A retrospective study in 433 cases
ConclusionsLCA on reported symptoms and signs in a retrospective study allowed different subgroups with meaningful clinical correlates to be defifined. These fifindings provide evidence for targeted prevention and treatment interventions. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - October 17, 2017 Category: Internal Medicine Source Type: research

In silico system pharmacology for the potential bioactive ingredients contained in Xingnaojing Injection ( 醒脑静注射液) and Its material basis for sepsis treatment
ConclusionsThe uncovered mechanism may offer a superior insight for understanding the theory of the Chinese herbal medicine for combating sepsis. Moreover, the potential inhibitors for the sepsis-related targets may provide a good source to find new lead compounds against sepsis disease. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - October 17, 2017 Category: Internal Medicine Source Type: research

Acupuncture alters pro-inflammatory cytokines in the plasma of maternally separated rat pups
AbstractObjectiveTo investigate the potential alleviating effects of acupuncture on maternal separation (MS)-induced changes in plasma pro-inflammatory cytokine levels of rat pups.MethodsOn postnatal day 15, rat pups were randomly assigned to 4 groups (n=6 per group) using a random number table: normal, MS, MS with acupuncture stimulation at Shenmen (HT 7) acupoint (MS+HT 7), and MS with acupuncture stimulation at Chengshan (BL 57) acupoint (MS+BL 57) groups. Rat pups in the normal group were housed with their mothers under standard conditions; those in the MS, MS+HT 7 and MS+BL 57 groups were maternally separated and indi...
Source: Chinese Journal of Integrative Medicine - October 6, 2017 Category: Internal Medicine Source Type: research

Review of Anemone raddeana Rhizome and its pharmacological effects
AbstractThe chemical compositions ofAnemone raddeana Rhizome, a kind of traditional Chinese medicine, were reviewed, along with its bioactivity and pharmacological properties and method improvements of extracting and detecting triterpenoid saponins.A. raddeana Rhizome is used to treat neuralgia and rheumatism, and is rich in triterpenoid saponins, most of which are pentacyclic, with oleanane as the nucleus. So far, 37 triterpenoid saponins have been determined from the herb. Its reported bioactivity and pharmacological properties have been described as anticancerous, antimicrobial, anti-inflammatory, analgesic, antipyretic...
Source: Chinese Journal of Integrative Medicine - October 6, 2017 Category: Internal Medicine Source Type: research

Review on antioxidants and evaluation procedures
AbstractAntioxidants are the substances that are capable of counteracting the damaging effects of the physiological process of oxidation occur in animal tissues. These may be nutrients (vitamins and minerals) as well as enzymes (proteins) in our body that assist in chemical reactions. They are believed to play a role in preventing the development of chronic diseases like cancer, diabetes, heart disease, stroke, Alzheimer's disease, rheumatoid arthritis, and cataracts etc. The present review article emphasizes on the various aspects of oxidants and antioxidants viz. definition, types, causes, mechanism, functions, adverse e...
Source: Chinese Journal of Integrative Medicine - October 6, 2017 Category: Internal Medicine Source Type: research

Effects of electroacupuncture on metabolic changes in motor cortex and striatum of 6-hydroxydopamine-induced Parkinsonian rats
ConclusionsEA treatment is able to normalize the metabolic balance in the primary motor cortex and striatum of PD rats, which may contribute to its therapeutic effect on motor deficits. The striatal Glx/Cr ratio may serve as a potential indicator of PD and a therapeutic target of EA treatment. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - October 6, 2017 Category: Internal Medicine Source Type: research

Analysis of herbal medicine prescriptions for patients in an academic Korean medical hospital: A cross sectional study of electronic medical records (2010 –2013)
ConclusionThis study analysis successfully determined the frequency of a variety of herbal medicines, and many restorative herbal medicines were identified and frequently administered. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - October 6, 2017 Category: Internal Medicine Source Type: research

Effect of Jiaotai Pill ( 交泰丸) on intestinal damage in partially sleep deprived rats
AbstractObjectiveTo explore the effect and mechanism of Jiaotai Pill ( 交泰丸, JTW) on intestinal mucosal damage in rats with chronic partial sleep deprivation (PSD).MethodsObesity resistant (OR) rats were selected, and underwent 4 h PSD by being exposed to environmental noise for 4 weeks. During the whole PSD period, JTW and estazolam were orally given to the rats respectively in the treating groups. Plasma concentration of lipopolysaccharide (LPS) which is the marker of gut-origin endotoxemia was examined. Intestinal morphology changes were observed by optical microscopy. The protein expression of occludin (Ocln) in t...
Source: Chinese Journal of Integrative Medicine - October 6, 2017 Category: Internal Medicine Source Type: research

Effect of Shen-Fu Injection ( 参附注射液) on hemodynamics in early volume resuscitation treated septic shock patients
ConclusionSFI significantly improved hemodynamic indices such as CI, GEDI, MAP and HR in early volume resuscitation treated septic shock patients. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - October 6, 2017 Category: Internal Medicine Source Type: research

Recent advances in Chinese medicine for contrast-induced nephropathy
(Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - October 6, 2017 Category: Internal Medicine Source Type: research

Effects of compound Zhebei Granule ( 复方浙贝颗粒) combined with doxorubicin on expression of specific surface antigens in mice with transplanted KG-1a cells
AbstractObjectiveTo investigate the effects of Compound Zhebei Granule ( 复方浙贝颗粒, CZG) combined with doxorubicin hydrochloride (adriamycin, ADM) on specific surface antigens in mice with KG-1a transplanted cells.MethodsA subcutaneous tumor xenograft model was established by injection of the acute myeloid leukemia cell line KG-1a into the axillary flanks of BALB/c-nude mice. Twenty-four tumor bearing mice were divided into 4 groups according to a random number table, including normal saline control group, ADM group, high-dose CZG group, and mid-dose CZG group, with 6 mice in each group. Drug administration occurr...
Source: Chinese Journal of Integrative Medicine - October 6, 2017 Category: Internal Medicine Source Type: research

Contrast-induced nephropathy —time for Western medicine and Chinese medicine to team up
(Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - October 6, 2017 Category: Internal Medicine Source Type: research

Targeting tumor-associated macrophages by anti-tumor Chinese materia medica
AbstractTumor-associated macrophages (TAMs) play a key role in all stages of tumorigenesis and tumor progression. TAMs secrete different kinds of cytokines, chemokines, and enzymes to affect the progression, metastasis, and resistance to therapy depending on their state of reprogramming. Therapeutic benefit in targeting TAMs suggests that macrophages are attractive targets for cancer treatment. Chinese materia medica (CMM) is an important approach for treating cancer in China and in the Asian region. According to the theory of Chinese medicine (CM) and its practice, some prescriptions of CM regulate the body's internal env...
Source: Chinese Journal of Integrative Medicine - October 1, 2017 Category: Internal Medicine Source Type: research

Chemical composition and pharmacological potential of aromatic water from Salix caprea inflorescence
ConclusionsThe aromatic water's composition and its pharmacological evaluations has been reported in our results for this unique and endemic species. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - September 29, 2017 Category: Internal Medicine Source Type: research

Chinese and Indian women ’s experience with alternative medications for menopause related symptoms: A qualitative analysis
ConclusionsChinese and Indian women used alternative medicine in prevention and treatment of menopause-related problems even as they were avoiding HRT because of the fear of side effects. They believed that their supplements were effective, safe and cost-beneficial even with long-term use. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - September 15, 2017 Category: Internal Medicine Source Type: research

Antihypercholesterolemic, antioxidant and renal protective effects of Mengkudu ( Rubiaceae ) fruit in nephropathy-induced albino rats
AbstractObjectiveTo assess the modulatory impact of alcoholic extract of fruit of Mengkudu (AEFM,Morinda citrifolia L., Rubiaceae) on renal oxido-lipidemic stress in hypercholesterolemic albino rats.MethodsTwenty-four male albino rats were randomly divided into four groups with six rats in each group: group I as control, group II fed with hypercholesterolemic diet (HCD) for 45 days (4% cholesterol and 1% cholic acid), Group III rats fed with HCD for 45 days + AEFM (300 mg/kg body weight/day orally) for last 30 days and group IV normal rats fed AEFM alone. The blood was collected using ethylenediamine tetraacetic acid (EDTA...
Source: Chinese Journal of Integrative Medicine - September 15, 2017 Category: Internal Medicine Source Type: research

Dampness-heat accelerates DMBA-induced mammary tumors in rats
AbstractObjectiveTo investigate the impact of dampness-heat (DH) on the development of mammary tumors in 7,12-dimethylbenz(a)anthracene (DMBA)-induced rats.MethodsForty rats were randomly divided into 3 groups in a randomized block design, including the control group (n=13), DMBA group (n=14), and DMBA plus DH group (n=13). Rats in the DMBA group and DMBA plus DH group were intragastrically administrated with DMBA (100 mg/kg) for twice, once per week, while rats in the control group were treated with equivalent volumes of sesame oil. After DMBA administration, rats in the DMBA plus DH group were exposed to a simulated clim...
Source: Chinese Journal of Integrative Medicine - September 15, 2017 Category: Internal Medicine Source Type: research

Salutary potential of ethanolic extract of avocado fruit on anomalous carbohydrate metabolic key enzymes in hepatic and renal tissues of hyperglycaemic albino rats
AbstractObjectiveTo assess the beneficial potential of ethanolic extract of avocado fruit on abnormal carbohydrate metabolic key enzymes in hepatic and renal tissues in streptozotocin (STZ) induced hyperglycemic albino rats.MethodsTwenty-four male albino rats were randomly divided into four groups with six in each group by simple random sampling method. Group 1 as control rats; Group 2 as STZ induced diabetic rats; Group 3 as diabetic rats treated with avocado fruit extract (AFE), 300 mg/kg as aqueous suspension orally for 30 days; Group 4 as diabetic rats treated with gliclazide (5 mg/kg) in aqueous solution orally for 30...
Source: Chinese Journal of Integrative Medicine - September 15, 2017 Category: Internal Medicine Source Type: research

Combination therapy of tacrolimus and Chinese herb medicated bath in children with inverse psoriasis
(Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - September 15, 2017 Category: Internal Medicine Source Type: research

Methological quality of systematic reviews and meta-analyses on acupuncture for stroke: A review of review
ConclusionsImportant methodological flaws were found in Chinese systematic reviews and primary studies. It was necessary to improve the methodological quality and reporting quality of both the systematic reviews published in China and primary studies on acupuncture for stroke. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - September 13, 2017 Category: Internal Medicine Source Type: research

Advantages of Chinese medicine for patients with acquired immunodeficiency syndrome in rural central China
AbstractObjectiveTo analyze the effect of Chinese medicine (CM) on mortality and quality of life (QOL) of acquired immunodeficiency syndrome (AIDS) patients treated with combined antiretroviral therapy (cART).MethodsA random sample of AIDS patients enrolled in the National Chinese Medicine Treatment Trial Program (NCMTP) that met the inclusion criteria was included in this study. NCMTP patients were included as the CM+cART group, and those not in the NCMTP were included as the cART group. Survival from September 2004 to September 2012 was analyzed by retrospective cohort study. QOL was analyzed by cross-sectional study.Res...
Source: Chinese Journal of Integrative Medicine - September 8, 2017 Category: Internal Medicine Source Type: research