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Shengmai San for Treatment of Cardiotoxicity from Anthracyclines: A Systematic Review and Meta-Analysis
ConclusionShengmai San has a positive effect on the treatment of cardiotoxicity from anthracyclines. However, in the future, it is still necessary to conduct high-quality RCTs to verify its efficacy. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - April 1, 2022 Category: Internal Medicine Source Type: research

Formulation and Interpretation of International Diagnostic Guidelines for Blood-Stasis Syndrome
(Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - April 1, 2022 Category: Internal Medicine Source Type: research

Effect of Shenmai Injection on Long-Term Prognosis of Patients with Chronic Heart Failure: A Multicenter, Large Sample Capacity, Long-Term Follow-Up Retrospective Cohort Study
ConclusionCombination with SMI on the standardized Western medicine treatment can effectively reduce cardiogenic mortality and readmission rate in CHF patients, and thereby improve the long-term prognosis. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - April 1, 2022 Category: Internal Medicine Source Type: research

International Diagnostic Guidelines for Blood-Stasis Syndrome
(Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - April 1, 2022 Category: Internal Medicine Source Type: research

Baicalein Attenuates Severe Polymicrobial Sepsis via lleviating Immune Dysfunction of T Lymphocytes and Inflammation
ConclusionBaicalein may be an effective immunomodulator that attenuates overwhelming inflammatory responses in severe abdominal sepsis. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - March 30, 2022 Category: Internal Medicine Source Type: research

Molecular Mechanism of Electroacupuncture Regulating Cerebral Arterial Contractile Protein in Rats with Cerebral Infarction Based on MLCK Pathway
ConclusionEA intervention can inhibit contraction of cerebral vascular smooth muscle cells and regulate smooth muscle relaxation by regulating MLCK pathway. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - March 27, 2022 Category: Internal Medicine Source Type: research

Yixin Ningshen Tablet Alleviates Comorbidity of Myocardial Infarction and Depression by Enhancing Myocardial Energy Metabolism and Increasing Availability of Monoamine Neurotransmitter
ConclusionsYXNS can relieve MI by enhancing myocardial energy metabolism. Meanwhile, YXNS can alleviate depression by resisting inflammation and increasing availability of monoamine neurotransmitters. It may be used as a potential drug to treat comorbidity of MI and depression. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - March 23, 2022 Category: Internal Medicine Source Type: research

Traditional Uses, Phytochemistry, Pharmacology and Toxicology of Rhizoma phragmitis: A Narrative Review
AbstractRhizoma phragmitis is a common Chinese herbal medicine whose effects are defined as ‘clearing heat and fire, promoting fluid production to quench thirst, eliminating irritability, stopping vomiting, and disinhibiting urine’. During the Novel Coronavirus epidemic in 2020, the Weijing Decoction and Wuye Lugen Decoction, withRhizoma phragmitis as the main herbal component, were included in The Pneumonia Treatment Protocol for Novel Coronavirus Infection (Trial Version 5) due to remarkable antiviral effects. Modern pharmacological studies have shown thatRhizoma phragmitis has antiviral, antioxidative, anti-inflamma...
Source: Chinese Journal of Integrative Medicine - March 23, 2022 Category: Internal Medicine Source Type: research

Inhibitory Effect of Resveratrol on LPS-induced Glomerular Mesangial Cells Proliferation and TGF- β1 Expression via Sphingosine Kinase 1 Pathway
ConclusionRSV inhibited LPS-induced GMCs proliferation and TGF- β1 expression, which may be independent of its hypoglycemic effect on preventing the development of mesangial cell fibrosis and closely related to the direct inhibition of SphK1 pathway. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - March 8, 2022 Category: Internal Medicine Source Type: research

Onset and Recurrence Characteristics of Chinese Patients with Noncardiogenic Ischemic Stroke in Chinese Medicine Hospital
ConclusionsRecurrence in minor and small-artery stroke cannot be ignored. Hypertension, dyslipidemia, abnormal HbA1c, intracranial artery stenosis and carotid plaque were more common in stroke patients. Particularly, phlegm-dampness and blood stasis syndromes, as well as qi deficiency and blood stasis constitutions, were still the main manifestations of stroke. (Trial registration at ClinicalTrials.gov No. NCT03174535) (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - March 8, 2022 Category: Internal Medicine Source Type: research

Protective Roles of Shilajit in Modulating Resistin, Adiponectin, and Cytokines in Rats with Non-alcoholic Fatty Liver Disease
ConclusionThe probable protective role of Shilajit in NAFLD model rats may be via modulating the serum levels of IL-1 β, TNF-α, IL-10, adipokine and resistin, and reducing of HOMA-IR. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - March 8, 2022 Category: Internal Medicine Source Type: research

Treatment of Lung Cancer with Orally Administered Chinese Herbal Medicine: An Evidence Map between 1970 –2020
ConclusionsCHM has staged and therapeutic advantages in treating lung cancer. The overall methodological quality is poor, and the level of evidence requires improvement. It is necessary to carry out large-scale, standardized, and higher-quality research in the superior and weak areas of CHM treatment of lung cancer. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - March 3, 2022 Category: Internal Medicine Source Type: research

Realgar ( α-As4S4) Treats Myelodysplastic Syndromes through Reducing DNA Hypermethylation
AbstractDNA hypermethylation is an epigenetic modification that plays a critical role in the oncogenesis of myelodysplastic syndromes (MDS). Aberrant DNA methylation represses the transcription of promotors of tumor suppressor genes, inducing gene silencing. Realgar ( α-As4S4) is a traditional medicine used for the treatment of various diseases in the ancient time. Realgar was reported to have efficacy for acute promyelocytic leukemia (APL). It has been demonstrated that realgar could efficiently reduce DNA hypermethylation of MDS. This review discusses the mechanisms of realgar on inhibiting DNA hypermethylation of MDS, ...
Source: Chinese Journal of Integrative Medicine - March 1, 2022 Category: Internal Medicine Source Type: research

Effects of Bushen Yiqi Huoxue Decoction in Treatment of Patients with Diminished Ovarian Reserve: A Randomized Controlled Trial
ConclusionsBYHD had a favorable therapeutic effect in patients with DOR by rebalancing hormone levels, promoting ovulation, and repairing the thin endometrium. The combination of tonifying Shen (Kidney), benefiting qi and activating blood circulation may be a promising therapeutic strategy for DOR. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - March 1, 2022 Category: Internal Medicine Source Type: research

Mechanisms of Acupuncture in Improving Alzheimer ’s Disease Caused by Mitochondrial Damage
In conclusion, these findings suggest that AD mitochondrial dysfunction represents a reasonable therapeutic target and acupunct ure could play a significant role in preventing and treating AD. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - March 1, 2022 Category: Internal Medicine Source Type: research