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Ginsenoside Rg1 Reduces Cardiotoxicity While Increases Cardiotonic Effect of Aconitine in vitro
ConclusionRg1 inhibited the cardiotoxicity and enhanced the cardiotonic effect of AC via regulating the ion channels pathway of [Na+], [K+], and [Ca2+]. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - June 20, 2022 Category: Internal Medicine Source Type: research

Evaluation of Renal Impairment in Patients with Diabetic Kidney Disease by Integrated Chinese and Western Medicine
ConclusionsMale, course of diabetes>60 months, anemia, hyperuricemia, massive proteinuria, atherosclerosis, and blood deficiency syndrome might indicate more severe degree of renal function damage in patients with DKD. (Registration No. NCT03865914) (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - June 9, 2022 Category: Internal Medicine Source Type: research

Buyang Huanwu Decoction Ameliorates Damage of Erectile Tissue and Function Following Bilateral Cavernous Nerve Injury
ConclusionsBHD can improve ED of rats with BCNI, which is related to inhibiting fibrosis, apoptosis, and oxidative stress of CC. The ROS/JNK/c-Jun signaling pathway may play an important role in the process. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - June 9, 2022 Category: Internal Medicine Source Type: research

Efficacy of Qizi Yusi Pill on Pregnancy Outcomes in Women of Advanced Reproductive Age: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial
ConclusionsQYP can enhance ovarian reserve capacity and ovarian response, and possibly promote endometrial receptivity. QYP effectively improves cumulative pregnancy rates in older patients ( ⩾35 years) undergoing IVF-ET. (Registration No. ChiCTR1800014427) (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - June 1, 2022 Category: Internal Medicine Source Type: research

Kang-Ai Injection Inhibits Gastric Cancer Cells Proliferation through IL-6/STAT3 Pathway
ConclusionKAI exerted an anti-proliferative function by inhibiting IL-6/STAT3 signaling pathway followed by the induction of G1 phase arrest in gastric cancer cells. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - May 25, 2022 Category: Internal Medicine Source Type: research

Danlou Tablet Improves Chronic Intermittent Hypoxia-Induced Dyslipidemia and Arteriosclerosis by HIF-1 α-Angptl4 mRNA Signaling Pathway
ConclusionDLT had positive effects in improving dyslipidemia and arteriosclerosis by inhibiting Angptl4 protein level through HIF-1 α-Angptl4 mRNA signaling pathway. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - May 25, 2022 Category: Internal Medicine Source Type: research

Active Components Formulation Developed from Fuzheng Huayu Recipe for Anti-Liver Fibrosis
ConclusionACF exerts a satisfactory effect against experimental liver fibrosis and attenuates sinusoidal capillarization, which warrant a further research and development for herbal components formulation on liver fibrosis. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - May 25, 2022 Category: Internal Medicine Source Type: research

A Breakthrough Point in Integrative Medical Research: Challenge of Treating Overlapping Symptoms in Functional Gastrointestinal Disorders
This article discusses the current status of diagnosis and treatment of FGIDs, the advantages and characteristics of CM treatment, and how integrated medicine can make a breakthrough in FGIDs diagnosis and treatment. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - May 25, 2022 Category: Internal Medicine Source Type: research

Molecular Mechanism of Polysaccharides Extracted from Chinese Medicine Targeting Gut Microbiota for Promoting Health
AbstractThe accumulating evidence revealed that gut microbiota plays an important role in pathological process of disease including obesity, type 2 diabetes mellitus, heart failure, and non-alcoholic fatty liver disease. Polysaccharides extracted from Chinese medicine (CM) can not only alleviate pathological status but also promote health by anti-inflammatory, regulating immunity, lowering blood glucose and lipids, anti-cancer, and anti-oxidation. The alterations of gut microbiota composition and metabolism pathways are the potential mechanisms of CM polysaccharides treatment. In addition, they exert functions through gut-...
Source: Chinese Journal of Integrative Medicine - May 18, 2022 Category: Internal Medicine Source Type: research

Chinese Medicine Meets Conventional Medicine in Targeting COVID-19 Pathophysiology, Complications and Comorbidities
ConclusionThe coordinated actions of each NHCC-recommended CM against a few targets of the major COVID-19 pathophysiology, complications and comorbidities, partly have common mechanisms with the conventional medicines. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - May 18, 2022 Category: Internal Medicine Source Type: research

Efficacy of Wen-Luo-Tong on Peripheral Neuropathy Induced by Chemotherapy or Target Therapy: A Randomized, Double-Blinded, Placebo-Controlled Trial
ConclusionWLT local administration was significantly effective in the treatment of patients with PN induced by chemotherapy or target therapy. (Trial registration No. ChiCTR1900023862) (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - May 18, 2022 Category: Internal Medicine Source Type: research

Transcutaneous Electrical Acupoint Stimulation Improving Postoperative Cognitive Function in Senior Patients Undergoing Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Trial
ConclusionApplication of TEAS in senior patients after VATS could reduce incidence of POCD and improve postoperative cognitive function. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - May 11, 2022 Category: Internal Medicine Source Type: research

Reduning Injection versus Neuraminidase Inhibitors in the Treatment of Influenza: A Systematic Review and Meta-Analysis
ConclusionsThis study provided low or very low evidence indicating Reduning Injection may be effective in the treatment of influenza and might be safe. Further rigorously designed studies are needed to confirm the effectiveness and safety of Reduning Injection and support it as a recommendation for influenza. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - May 4, 2022 Category: Internal Medicine Source Type: research

Patients with Metastatic Colorectal Cancer after Failure of Second-Line Treatment May Benefit from Low-Dose Apatinib and S-1 Combined with Jianpi Bushen Jiedu Decoction
ConclusionsPatients with mCRC after failure of the second or above lines of treatment may potentially benefit from the treatment of low-dose apatinib and S-1 combined with JBJD because of its similar effect as the standard dose of target therapy and relatively better safety. (Registration No. ChiCTR1900022673) (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - May 4, 2022 Category: Internal Medicine Source Type: research

Electroacupuncture in Treatment of Acute Gastrointestinal Injury in Patients with Severe Traumatic Brain Injury: A Multicenter Randomized Controlled Trial
ConclusionEarly EA can improve gastrointestinal function and clinical prognosis in patients with severe TBI complicated by AGI. (Registration No. ChiCTR2000032276) (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - May 4, 2022 Category: Internal Medicine Source Type: research