Chinese Journal of Integrative Medicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Effects of Total Saponins from Dioscorea Nipponica Makino on Monosodium Urate-Induced M1-Polarized Macrophages through Arachidonic Acid Signaling Pathway: An in vitro Study
ConclusionTSDN has an anti-inflammation effect on gouty arthritis in anin vitro model by regulating arachidonic acid signaling pathway. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 12, 2022 Category: Internal Medicine Source Type: research

A Data Mining-Based Study on Medication Rules of Chinese Herbs to Treat Heart Failure with Preserved Ejection Fraction
ConclusionsHFPEF is the syndrome of root vacuity and tip repletion, and its core pathogenesis is “deficiency”, “stasis”, and “water”, with “deficiency” being the most principal, which is closely related to Xin (heart), Fei (Lung), and Pi (Spleen). The treatment of this disease occurs by improving qi, warming yang, activating blood and inducing diuresis.Astragali Radix (Huangqi) withSalviae Miltiorrhizae Radix Et Rhizoma (Danshen) is the basic combination of herbs applied. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 12, 2022 Category: Internal Medicine Source Type: research

Prevention of Deep Vein Thrombosis by Panax Notoginseng Saponins Combined with Low-Molecular-Weight Heparin in Surgical Patients
ConclusionCombined application of PNS and LMWH can effectively reduce the incidence of DVT among surgical inpatients compared with LMWH monotherapy, without increased risk of bleeding. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 12, 2022 Category: Internal Medicine Source Type: research

Mining Therapeutic Efficacy from Treasure Chest of Biodiversity and Chemodiversity: Pharmacophylogeny of Ranunculales Medicinal Plants
AbstractRanunculales, comprising of 7 families that are rich in medicinal species frequently utilized by traditional medicine and ethnomedicine, represents a treasure chest of biodiversity and chemodiversity. The phylogenetically related species often have similar chemical profile, which makes them often possess similar therapeutic spectrum. This has been validated by both ethnomedicinal experiences and pharmacological investigations. This paper summarizes molecular phylogeny, chemical constituents, and therapeutic applications of Ranunculales, i.e., a pharmacophylogeny study of this representative medicinal order. The phy...
Source: Chinese Journal of Integrative Medicine - July 9, 2022 Category: Internal Medicine Source Type: research

Progress in Mechanism of Astragalus membranaceus and Its Chemical Constituents on Multiple Sclerosis
AbstractThe primary chemical components ofAstragalus membranaceus include polysaccharides, saponins, flavonoids, and amino acids. Recent studies have shown thatAstragalus membranaceus has multiple functions, including improving immune function and exerting antioxidative, anti-radiation, anti-tumor, antibacterial, antiviral, and hormone-like effects.Astragalus membranaceus and its extracts are widely used in clinical practice because they have obvious therapeutic effects against various autoimmune diseases and relatively less adverse reaction. Multiple sclerosis (MS) is an autoimmune disease of central nervous system (CNS),...
Source: Chinese Journal of Integrative Medicine - July 9, 2022 Category: Internal Medicine Source Type: research

Casticin Attenuates Stemness in Cervical Cancer Stem-Like Cells by Regulating Activity and Expression of DNMT1
ConclusionCAS effectively inhibits stemness in CCSLCs through suppression of DNMT1 activation, suggesting that CAS acts as a promising preventive and therapeutic candidate in cervical cancer. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 9, 2022 Category: Internal Medicine Source Type: research

Therapeutic Properties of Flavonoids in Treatment of Cancer through Autophagic Modulation: A Systematic Review
AbstractCancers have high morbidity and mortality rates worldwide. Current anticancer therapies have demonstrated specific signaling pathways as a target in the involvement of carcinogenesis. Autophagy is a quality control system for proteins and plays a fundamental role in cancer carcinogenesis, exerting an anticarcinogenic role in normal cells and can inhibit the transformation of malignant cells. Therefore, drugs aimed at autophagy can function as antitumor agents. Flavonoids are a class of polyphenolic secondary metabolites commonly found in plants and, consequently, consumed in diets. In this review, the systematic se...
Source: Chinese Journal of Integrative Medicine - July 9, 2022 Category: Internal Medicine Source Type: research

Protective Mechanism of Electroacupuncture on Peripheral Neurotoxicity Induced by Oxaliplatin in Rats
ConclusionEA may be a potential alternative therapy for OIPN, and its mechanism may be mainly mediated by restoring the Nrf2/HO-1 signaling pathway. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 7, 2022 Category: Internal Medicine Source Type: research

Echinacoside Alleviates Cognitive Impairment in Cerebral Ischemia Rats through α 7nAChR-Induced Autophagy
ConclusionECH treatment helped improve cognitive impairment by attenuating neurological damage and enhancing autophagy in MCAO rats. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 7, 2022 Category: Internal Medicine Source Type: research

Resveratrol Modulates Bone Mineral Density and Bone Mineral Content in A Rat Model of Male Hypogonadism
ConclusionRes could ameliorate bone loss induced by male hypogonadism, possible via restoration of the normal balance between RANK and OPG. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 7, 2022 Category: Internal Medicine Source Type: research

Acupoint Autohemotherapy Attenuates Atopic Dermatitis Lesions by Regulating Th1/Th2 Balance in DNCB-Induced BALB/c Mice
ConclusionA-AHT showed significant effectiveness on the AD model mice, through regulating Th1/Th2 immune responses. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 1, 2022 Category: Internal Medicine Source Type: research

Efficacy and Safety of Lianhua Qingwen for Patients with COVID-19: A Systematic Review and Meta-Analysis
ConclusionsLHQW was more suitable for treating COVID-19 patients with obvious expectoration, shortness of breath and muscle soreness. LHQW had advantages in treating COVID-19 with no obvious exacerbation. (PROSPERO No. CRD42021235937) (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 1, 2022 Category: Internal Medicine Source Type: research

Ruyi Zhenbao Pills for Patients with Motor and Sensory Dysfunction after Stroke: A Double-Blinded, Randomized Placebo-Controlled Clinical Trial
ConclusionRZPs improved limb motor, balance, and sensory functions of stroke patients during recovery period with good safety. (Trial registration No. NCT04029701) (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - June 20, 2022 Category: Internal Medicine Source Type: research

Analysis of Chinese Medical Syndrome Features of Ischemic Stroke Based on Similarity of Symptoms Subgroup
ConclusionsThere were 7 main symptom similarity-based subgroups in ischemic stroke patients, and their specific characteristics were obvious. The main syndromes were wind phlegm pattern and hyperactivity of Gan yang pattern. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - June 20, 2022 Category: Internal Medicine Source Type: research

Evidence-Based Dampness-Heat ZHENG (Syndrome) in Cancer: Current Progress toward Establishing Relevant Animal Model with Pancreatic Tumor
This study aims to provide comprehensive insight that can be used for the establishment of a future standardizedZHENG-based cancer animal model. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - June 20, 2022 Category: Internal Medicine Source Type: research