Chinese Journal of Integrative Medicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Network Pharmacology and Experimental Validation to Explore Mechanism of Tetrahydropalmatine on Acute Myocardial Ischemia
ConclusionsTHP could improve cardiac function and alleviate myocardial injury in AMI. The underlying mechanism may be inhibition of inflammation, the improvement of energy metabolism and the regulation of hormones. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - August 22, 2023 Category: Internal Medicine Source Type: research

Inflammatory and Immunomodulatory Effects of Tripterygium wilfordii Multiglycoside in Mouse Models of Psoriasis Keratinocytes
ConclusionsTGW improved psoriasis-like inflammation by inhibiting KCs proliferation, as well as the associated immune cells and cytokine expression. It inhibited IL-17 secretion from γ δ T cells, which improved the immune-inflammatory microenvironment of psoriasis. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - August 19, 2023 Category: Internal Medicine Source Type: research

Immunoregulatory and Anti-cancer Activities of Combination Treatment of Novel Four-Herb Formula and Doxorubicin in 4T1-Breast Cancer Bearing Mice
ConclusionThe above results provide evidence for evaluating the immune regulating mechanisms of 4HF in breast cancer and support its clinical significance in its potential as an adjunctive therapeutic agent or immune supplement. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - August 18, 2023 Category: Internal Medicine Source Type: research

Effectiveness of Zhenqi Buxue Oral Liquid Combined with Progesterone for Treatment of Oligomenorrhea and Hypomenorrhea with Qi-Blood and Kidney (Shen) Essence Deficiency: A Randomized Controlled Trial
ConclusionsThe combination of ZQ and PG, or ZQ only had better effects on reducing TCMSS scores compared with PG, and COM showed the higher total effective rate compared with monotherapy. Besides, COM could effectively improve menstrual blood loss and quality of life. ZQ combined with PG may be an effective and safe option for oligomenorrhea and hypomenorrhea patients with qi-blood and Shen essence deficiency. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - August 18, 2023 Category: Internal Medicine Source Type: research

Danhong Injection Up-regulates miR-125b in Endothelial Exosomes and Attenuates Apoptosis in Post-Infarction Myocardium
ConclusionDHI and DHI-induced exosomes inhibited apoptosis, promoted the miR-125b expression level, and regulated the p53 apoptotic pathway in post-infarction myocardium. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - August 18, 2023 Category: Internal Medicine Source Type: research

Application and Effectiveness of Chinese Medicine in Regulating Immune Checkpoint Pathways
In this study, we analyzed the modulation and mechanisms of immune checkpoint molecules associated with different coinhibitory and costimulatory molecules, and reviewed the immune functions of related molecules and CM studies in treating autoimmune diseases and tumors. By summarizing the characteristics and research value of CM in regulating immune checkpoint molecules, this review aims to provide a useful reference for future studies in this field. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - August 15, 2023 Category: Internal Medicine Source Type: research

Placebo Response among Different Types of Sham Acupuncture for Low Back Pain: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
ConclusionsSham acupuncture is associated with a large placebo response in pain intensity among patients with LBP. Researchers should also be aware that the types of sham acupuncture applied may potentially impact the evaluation of the efficacy of acupuncture. Nonetheless, considering the nature of placebo response, the effect of other contextual factors cannot be ruled out in this study. (PROSPERO registration No. CRD42022304416) (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - August 15, 2023 Category: Internal Medicine Source Type: research

Acupuncture for Patients with Chronic Spontaneous Urticaria: A Randomized, Sham-Controlled Pilot Trial
ConclusionsActive acupuncture had a better improvement trend in alleviating symptoms, improving quality of life and regulating the mood of anxiety and depression in patients with CSU than sham acupuncture. (Registration Nos. AMCTR-ICR-18000190 and ChiCTR2100054776) (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - August 10, 2023 Category: Internal Medicine Source Type: research

Polypeptide from Moschus Suppresses Lipopolysaccharide-Induced Inflammation by Inhibiting NF- κ B-ROS/NLRP3 Pathway
ConclusionPPM could attenuate LPS-induced inflammation by inhibiting the NF- κB-ROS/NLRP3 pathway, and may be a novel potential candidate drug for treating inflammation and inflammation-related diseases. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - August 5, 2023 Category: Internal Medicine Source Type: research

Organic Integration of Traditional Chinese and Western Medicines —Future of Clinical Practice Guidelines of Integrated Traditional Chinese and Western Medicines
AbstractThe transformation and implementation of clinical practice guidelines for integrated traditional Chinese medicine (TCM) and Western medicine (WM) is crucial to the adoption of medical science and technological findings and is an important way for TCM to be made available to the world. First, clinical practice guidelines (CPGs) of TCM and WM integration in recent years was analyzed to clarify the current situation and problems in the existing guidelines according to the following four perspectives: (1) perspective of TCM and WM integration in guidelines, (2) diagnosis Using integrated TCM and WM, (3) integration of ...
Source: Chinese Journal of Integrative Medicine - August 2, 2023 Category: Internal Medicine Source Type: research

Guanxin V Relieves Ventricular Remodeling by Inhibiting Inflammation: Implication from Virtual Screening, Systematic Pharmacology, Molecular Docking, and Experimental Validation
ConclusionGuanxin V relieves ventricular remodeling by regulating inflammation, which provides new ideas for the anti-ventricular remodeling mechanism of Guanxin V. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - August 2, 2023 Category: Internal Medicine Source Type: research

Reyanning Mixture on Asymptomatic or Mild SARS-CoV-2 Infection in Children and Adolescents: A Randomized Controlled Trial
ConclusionAdding RYN to standard care may be a safe and effective treatment for children with asymptomatic and mild SARS-CoV-2 infection. (Registration No. ChiCTR2200060292) (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 31, 2023 Category: Internal Medicine Source Type: research

Effects of Acupotomy on Immobilization-Induced Gastrocnemius Contracture and Fibrosis in Rats via Wnt/ β-Catenin Signaling
ConclusionImprovements in motor function, muscle contractures, and muscle fibrosis induced by acupotomy correlates with the inhibition of Wnt/ β-catenin signaling pathway. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 12, 2023 Category: Internal Medicine Source Type: research

Bloodletting Acupuncture at Jing-Well Points on Hand Induced Autophagy to Alleviate Brain Injury in Acute Altitude Hypoxic Rats by Activating PINK1/Parkin Pathway
ConclusionBAJP was an effective treatment for AHH-induced brain injury, and the mechanism might be through reducing hippocampal tissue injury via increasing the PINK1/Parkin pathway and enhancement of mitochondrial autophagy. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 12, 2023 Category: Internal Medicine Source Type: research

Anti-oxidant and Anti-inflammatory Effects of Ethanol Extract from Polygala sibirica L. var megalopha Fr. on Lipopolysaccharide-Stimulated RAW264.7 Cells
ConclusionEEP inhibited inflammatory responses in activated macrophages through blocking MAPK/NF- κ B pathway and protected against oxidative stress. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 12, 2023 Category: Internal Medicine Source Type: research