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Acute Developmental Toxicity of Panax notoginseng in Zebrafish Larvae
ConclusionThis report uncovers the developmental toxicity of dPN, suggesting potential risk of its clinical application in children. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - January 27, 2022 Category: Internal Medicine Source Type: research

Total Ginsenoside Extract from Panax ginseng Enhances Neural Stem Cell Proliferation and Neuronal Differentiation by Inactivating GSK-3 β
ConclusionTG promoted NSC proliferation and neuronal differentiation by inactivating GSK-3 β. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - January 27, 2022 Category: Internal Medicine Source Type: research

Attenuation of Oxidative Stress-Induced Cell Apoptosis and Pyroptosis in RSC96 Cells by Salvianolic Acid B
ConclusionSal B may protect RSC96 cells against HG-induced cellular injury via the inhibition of apoptosis and pyroptosis activated by ROS. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - January 27, 2022 Category: Internal Medicine Source Type: research

Anti-anger Effects of Herbal Medicine: A Mini-Review of Rat Studies
ConclusionsThis review found the frequent methods to establish an anger model, and major mechanisms of anti-anger effects of HMs. Interestingly, some Liver qi-smoothing herbs have been frequently used to investigate the anti-anger effects of HM. These findings provide insight into the role and relevance of HMs in the field of anger management. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - January 27, 2022 Category: Internal Medicine Source Type: research

Enhancement of Swimming Endurance by Herbal Supplement M3P
ConclusionM3P supplementation may improve swimming endurance accompanied by increasing hepatic glycogen content and serum cortisol level without major toxicity. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - January 20, 2022 Category: Internal Medicine Source Type: research

Effect of Wrist-Ankle Acupuncture on Postoperative Analgesia after Total Knee Arthroplasty
ConclusionsWAA could alleviate post-TKA pain, improve knee joint function, and reduce the sufentanil consumption within 48 h of PCA pump. WAA is a safe and effective treatment in the perioperative analgesic management for TKA. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - January 19, 2022 Category: Internal Medicine Source Type: research

Efficacy and Safety of Mulberry Twig Alkaloids Tablet for Treatment of Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled Multicenter Clinical Study
ConclusionSZ-A are effective and safe for treatment of type 2 diabetes. The protocol was registered inhttp://www.chictr.org.cn/showproj.aspx?proj=60117 (ChiCTR2000038550) (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - January 19, 2022 Category: Internal Medicine Source Type: research

Correlation between Characteristics of Coronary Plaque and Chinese Medicine Syndromes of Coronary Heart Disease: A Cross-Sectional Study Analysed by Intravascular Ultrasound
ConclusionsCoronary plaque characteristics were correlated with different CM syndromes. Patients with PBS were associated with a higher degree of calcified plaque and severe coronary artery stenosis, indicating poor clinical prognosis but with a low probability of acute coronary events. In contrast, the degree of calcified plaque in patients with BSS remained relatively low, and plaque was more vulnerable, resulting in the possibility of the occurrence of acute coronary events remaining high. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - January 19, 2022 Category: Internal Medicine Source Type: research

Andrographolide Inhibits Proliferation and Promotes Apoptosis in Bladder Cancer Cells by Interfering with NF- κB and PI3K/AKT Signaling In Vitro and In Vivo
ConclusionsAndrographolide inhibits proliferation and promotes apoptosis in bladder cancer cells by interfering with NF- κB and PI3K/AKT signalingin vitro andin vivo. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - January 19, 2022 Category: Internal Medicine Source Type: research

Medication Rule Analysis of the Diagnosis and Treatment Programs of Chinese Medicine for the Prevention and Treatment of COVID-19 in China
ConclusionsCM for COVID-19 prevention mainly focuses on improving human immunity; for treatment, prescription focuses on clearing the lungs and removing dampness. Prescriptions vary with regions, perhaps due to climatic and environmental differences, which help clinicians to quickly make CM plans and treat patients according to clinical status, further minimizing resource wastage. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - January 13, 2022 Category: Internal Medicine Source Type: research

New Proposals for Application of Terahertz Imaging Technique in Chinese Medicine
AbstractThe rapid development of terahertz technology promotes the realization of various terahertz imaging systems. Terahertz technology features terahertz waves as good non-invasive illumination sources due to their high spectral resolution, penetration and safety. The terahertz imaging technique (TIT) has gradually been extended from the biomedical field to the field of Chinese medicine (CM), and it has become a powerful tool for seeking scientific evidence for CM theories with the use of modern science and technology. This paper reviews the current application of TITs in the field of CM research, and most importantly o...
Source: Chinese Journal of Integrative Medicine - January 13, 2022 Category: Internal Medicine Source Type: research

A Network Pharmacology-Based Study on Antidepressant Effect of Salicornia europaea L. Extract with Experimental Support in Chronic Unpredictable Mild Stress Model Mice
ConclusionThe SE extract may have an antidepressant effect, which appeared to regulate Nrf2-ARE pathway and increased levels of DA and CORT in the hippocampus and cortex. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - January 13, 2022 Category: Internal Medicine Source Type: research

Protective Effect of Shenfu Injection ( 参附注射液) on Vascular Endothelial Damage in a Porcine Model of Hemorrhagic Shock
ConclusionSFI attenuated endothelial injury in the porcine model of HS by inhibiting cell apoptosis, suppressing the formation of proinflammatory cytokines, and reducing endothelial activation. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - January 13, 2022 Category: Internal Medicine Source Type: research

Treatment Progress in Diminished Ovarian Reserve: Western and Chinese Medicine
AbstractDiminished ovarian reserve (DOR), generally defined as a decreased number or quality of oocytes, has a significant impact on quality of life and fertility in women. In recent years, the incidence of DOR has been increasing and the ages of patients are younger. The search for an effective DOR treatment has emerged as one of the preeminent research topics in reproductive health. An effective DOR therapy would improve ovarian function, fertility, and quality of life in patients. In this review we evaluated DOR treatment progress both in Western medicine and Chinese medicine, and elucidated the characteristics of each ...
Source: Chinese Journal of Integrative Medicine - January 11, 2022 Category: Internal Medicine Source Type: research

Schisandrin B Inhibits NLRP3 Inflammasome Pathway and Attenuates Early Brain Injury in Rats of Subarachnoid Hemorrhage
ConclusionSch B attenuated SAH-induced EBI, which might be associated with the inhibition of neuroinflammation, neuronal apoptosis, and the NLRP3 inflammatory signaling pathway. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - January 11, 2022 Category: Internal Medicine Source Type: research