Characterization and Comparison Analysis of WHO Monographs on Selected Medicinal Plants and ISO Standards of Chinese Materia Medica
AbstractMedicinal plants or Chinese materia medica (CMM) are now attracting worldwide attention as they have increasingly prominent advantages over chemical drugs in disease treatment and healthcare. Since the 1990s, World Health Organization (WHO) and International Organization for Standardization established the Technical Committee of Traditional Chinese Medicine (ISO/TC 249) have carried out the development of quality standards on medicinal plants or CMMs respectively, and a considerable number of monographs and international standards have been published. Since the two international organizations adhere to different pr...
Source: Chinese Journal of Integrative Medicine - May 4, 2022 Category: Internal Medicine Source Type: research

A Novel Diagnostic and Therapeutic Strategy for Cancer Patients by Integrating Chinese Medicine Syndrome Differentiation and Precision Medicine
AbstractApplying Chinese medicine (CM) is an important strategy for malignant tumor treatment in China. One of the significant characteristics of CM is to treat diseases based on syndrome differentiation. For Western medicine, it is of important clinical significance to formulate guidelines for the diagnosis and treatment of cancer patients based on the characteristics of disease differentiation. In Chinese clinical practice, the combination of disease differentiation and syndrome differentiation is an important feature for cancer treatment in the past. Currently, molecular profiling and genomic analysis-based precision me...
Source: Chinese Journal of Integrative Medicine - May 4, 2022 Category: Internal Medicine Source Type: research

Effectiveness and Safety of Baidu Jieduan Granules for COVID-19: A Retrospective Observational Multicenter Study
ConclusionBDJDG may be effective and safe for treatment of common type COVID-19. (Registration No. ChiCTR2000030836) (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - May 4, 2022 Category: Internal Medicine Source Type: research

Frequently Used Allopathic and Traditional Medicine for COVID-19 Treatment and Feasibility of Their Integration
AbstractTo date, no satisfactory treatment for COVID-19 is available. This review reported few recent updates regarding the drugs (allopathy/traditional medicines) used for the treatment of COVID-19 concerning clinical studies. Content of the article spotlight the contribution of allopathic and Ayurvedic drugs to the scientific basis for utilization as a potential therapy against COVID-19 infection and provide new insights on the integration of allopathy and traditional medicine. It advocated the combination of these two systems of treatment will ascertain their integrations, and there would be a good possibility and scope...
Source: Chinese Journal of Integrative Medicine - May 4, 2022 Category: Internal Medicine Source Type: research

Potential Mechanisms and Effects of Chinese Medicines in Treatment of Diabetic Atherosclerosis by Modulating NLRP3 Inflammasome: A Narrative Review
AbstractNucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) is an intracellular sensor that detects endogenous danger signals and environmental irritants to assemble into the NLRP3 inflammasome. Activation of the NLRP3 inflammasome leads to the secretion of the proinflammatory cytokines interleutkin (IL)-1 β and IL-18 and induces pyroptosis. Recent studies have shown that the NLRP3 inflammasome participates in the initiation and progression of diabetic atherosclerosis through pathological mechanisms such as β-cell dysfunction, insulin resistance, endothelial cell dysfunction, ...
Source: Chinese Journal of Integrative Medicine - May 4, 2022 Category: Internal Medicine Source Type: research

Mechanism of Fuzheng Kang ’ai Formula Regulating Tumor Microenvironment in Non-Small Cell Lung Cancer
ConclusionFZKA could directly bind to CCNA2 and inhibit tumor growth by regulating CCNA2 downstream genes and TME of NSCLC closely related to CCNA2. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - April 30, 2022 Category: Internal Medicine Source Type: research

Effectiveness and Safety of Chinese Medicine at Shenque (CV 8) for Primary Dysmenorrhea: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
ConclusionsNavel therapy appears to be more effective than Western medicine in decreasing menstrual pain and improving overall symptoms of PD. However, these findings need to be confirmed by well-designed clinical trials with adequate sample size (Systematic review registration at PROSPERO, No. CRD42021240350) (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - April 15, 2022 Category: Internal Medicine Source Type: research

Medical Therapy of Hearing Impairment and Tinnitus with Chinese Medicine: An Overview
AbstractThe current review gives a comprehensive overview of the recent development in Chinese medicine (CM) for treating several kinds of acquired nerve deafness and tinnitus, as well as links the traditional principle to well-established pharmacological mechanisms for future research. To date, about 24 herbal species and 40 related ingredients used in CM to treat hearing loss and tinnitus are reported for the treatment of endocochlear potential, endolymph growth, lowering toxic and provocative substance aggregation, inhibiting sensory cell death, and retaining sensory transfer. However, there are a few herbal species tha...
Source: Chinese Journal of Integrative Medicine - April 13, 2022 Category: Internal Medicine Source Type: research

Efficacy and Safety of Guihuang Formula in Treating Type III Prostatitis Patients with Dampness-Heat and Blood Stasis Syndrome: A Randomized Controlled Trial
ConclusionGHF is effective in treating type III prostatitis patients with dampness-heat and blood stasis syndrome without serious AEs. (Registration No. ChiCTR1900026966) (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - April 13, 2022 Category: Internal Medicine Source Type: research

Acupuncture and Moxibustion Inhibited Intestinal Epithelial-Mesenchymal Transition in Patients with Crohn ’s Disease Induced by TGF- β 1/Smad3/Snail Pathway: A Clinical Trial Study
ConclusionsMoxibustion at 43 °C combined with acupuncture may suppress TGF-β 1/Smad3/Snail pathway-mediated epithelial-mesenchymal transition of intestinal epithelial cells in Crohn’s disease patients by inhibiting the expression levels of TGF-β 1, Tβ R2, Smad3, and Snail. (Registration No. ChiCTR-IIR-16007751) (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - April 13, 2022 Category: Internal Medicine Source Type: research

Effects of Acupuncture on Endometrium and Pregnancy Outcomes in Patients with Polycystic Ovarian Syndrome Undergoing In Vitro Fertilization-Embryo Transfer: A Randomized Clinical Trial
ConclusionAcupuncture can improve the proportion of type A endometrium, regulate the levels of serum E2 and P on the day of hCG injection, and improve the pregnancy rate in patients with PCOS infertility undergoing IVF-ET. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - April 13, 2022 Category: Internal Medicine Source Type: research

Evidence for Anticancer Effects of Chinese Medicine Monomers on Colorectal Cancer
AbstractColorectal cancer is one of the most commonly occurring cancers worldwide. Although clinical reports have indicated the anticancer effects of Chinese herbal medicine, the multiple underlying molecular and biochemical mechanisms of action remain to be fully characterized. Chinese medicine (CM) monomers, which are the active components of CM, serve as the material basis of the functional mechanisms of CM. The aim of this review is to summarize the current experimental evidence fromin vitro, in vivo, and clinical studies for the effects of CM monomers in colorectal cancer prevention and treatment, providing some usefu...
Source: Chinese Journal of Integrative Medicine - April 13, 2022 Category: Internal Medicine Source Type: research

Mechanism of Acupuncture and Moxibustion on Promoting Mucosal Healing in Ulcerative Colitis
This study aims to review the achievements of acupuncture and moxibustion on mucosal healing and analyse the underlying mechanisms. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - April 12, 2022 Category: Internal Medicine Source Type: research

Composite Sophora Colon-Soluble Capsule Ameliorates DSS-Induced Ulcerative Colitis in Mice via Gut Microbiota-Derived Butyric Acid and NCR+ ILC3
ConclusionCSCC may exert a therapeutic effect on UC by improving the gut microbiota, promoting metabolite butyric acid production, and managing the ratio between NCR+ ILC3s and Lti ILC3s. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - April 12, 2022 Category: Internal Medicine Source Type: research

Schisandra chinensis Oil Attenuates Aristolochic Acid I-Induced Nephrotoxicity in vivo and in vitro
ConclusionsSCEO can alleviate AA I-induced kidney damage bothin vivo andin vitro. The protective mechanism may be closely related to the regulation of metabolic enzymes, thereby inhibiting apoptosis and ROS production. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - April 7, 2022 Category: Internal Medicine Source Type: research