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Huangqin Decoction Delays Progress of Colitis-Associated Carcinogenesis by Regulating Nrf2/HO-1 Antioxidant Signal Pathway in Mice
ConclusionHQD may regulate the expression of Nrf2 and HO-1 in colon tissue, reduce the expression of MDA and increase the expression of SOD in serum, thus delaying the progress of CAC in AOM/DSS mice. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 12, 2023 Category: Internal Medicine Source Type: research

Schisandrin B Protects against Ischemic Brain Damage by Regulating PI3K/AKT Signaling in Rats
ConclusionsSch B reduced apoptosis, inflammatory response, and oxidative stress of MCAO rats by modulating the PI3K/AKT pathway. Sch B had a potential for treating cerebral ischemia. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - June 26, 2023 Category: Internal Medicine Source Type: research

Baicalin Antagonizes Prostate Cancer Stemness via Inhibiting Notch1/NF- κB Signaling Pathway
ConclusionMechanistically, baicalin exhibited a potential therapeutic effect on PCa via inhibiting the Notch1/NF- κB signaling pathway and its mediated cancer stemness. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - June 26, 2023 Category: Internal Medicine Source Type: research

Flavonoid Myricetin as Potent Anticancer Agent: A Possibility towards Development of Potential Anticancer Nutraceuticals
AbstractGood nutrition plays a crucial role in maintaining a balanced lifestyle. The beneficial effects of nutrition have been found to counteract nutritional disturbances with the expanded use of nutraceuticals to treat and manage cardiovascular diseases, cancer, and other developmental defects over the last decade. Flavonoids are found abundantly in plant-derived foods such as fruits, vegetables, tea, cocoa, and wine. Fruits and vegetables contain phytochemicals like flavonoids, phenolics, alkaloids, saponins, and terpenoids. Flavonoids can act as anti-inflammatory, anti-allergic, anti-microbial (antibacterial, antifunga...
Source: Chinese Journal of Integrative Medicine - June 21, 2023 Category: Internal Medicine Source Type: research

Effectiveness of Acupoint Application in Patients with Pharyngeal Pain: Evidence from CHUNBO, A Prospective Real-World Study
ConclusionsAcupoint application in patients with pharyngeal pain resulted in improved effective rate and shortened duration, especially children aged 3 –6 years old, and those with tonsil diseases. Acupoint of RN 22, RN 8 and DU 14,Natrii sulfas, Radix et Rhizoma Rhei, andHerba Ephedrae were the most commonly used herbs in the treatment of pharyngeal pain. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - June 21, 2023 Category: Internal Medicine Source Type: research

Polysaccharide of Alocasia cucullata Exerts Antitumor Effect by Regulating Bcl-2, Caspase-3 and ERK1/2 Expressions during Long-Time Administration
ConclusionsLong-time administration of PAC can significantly inhibit viability and promote apoptosis of tumor cells, and had obvious antitumor effect in tumor-bearing mice. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - June 21, 2023 Category: Internal Medicine Source Type: research

Yinlai Decoction Protects Microstructure of Colon and Regulates Serum Level of D-Lactic Acid in Pneumonia Mice Fed with High-Calorie and High-Protein Diet
ConclusionsYD can protect function of intestinal mucosa by improving the tissue morphology of intestinal mucosa and maintaining integrity of cell connections and microvilli structure, thereby reducing permeability of intestinal mucosa to regulate the serum levels of DLA in mice. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - June 21, 2023 Category: Internal Medicine Source Type: research

Naringin Inhibits Colorectal Carcinogenesis by Inhibiting Viability of Colorectal Cancer Cells
ConclusionNaringin inhibited colorectal carcinogenesis by inhibiting viability of CRC cells. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - June 21, 2023 Category: Internal Medicine Source Type: research

Comparison of Effects of Liuzijue Exercise and Conventional Respiratory Training on Patients after Cardiac Surgery: A Randomized Controlled Trial
ConclusionsLE is safe and feasible for improving pulmonary function, respiratory muscle strength, the ability to complete activities of daily living and for relieving anxiety of patients after cardiac surgery (Registration No. ChiCTR2200062964). (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - May 27, 2023 Category: Internal Medicine Source Type: research

Total Glucosides of Paeony Regulate Immune Imbalance Mediated by Dermal Mesenchymal Stem Cells in Psoriasis Mice
ConclusionTGP may exert a good therapeutic effect on psoriasis by regulating the immune imbalance of DMSCs. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - May 25, 2023 Category: Internal Medicine Source Type: research

Intelligent Chinese Medicine: A New Direction Approach for Integrative Medicine in Diagnosis and Treatment of Cardiovascular Diseases
In this study, we explored the role of AI in CM in the diagnosis and treatment of CVDs, and discussed application of AI in assessing the effect of CM on CVDs. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - May 24, 2023 Category: Internal Medicine Source Type: research

Efficacy and Safety of Huashi Baidu Granules in Treating Patients with SARS-CoV-2 Omicron Variant: A Single-Center Retrospective Cohort Study
ConclusionHSBD treatment significantly shortened the negative conversion time of nuclear acid, the length of hospitalization, and the time of the first nucleic acid negative conversion in patients infected with SARS-COV-2 Omicron variant (Trial registry No. ChiCTR2200060472). (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - May 24, 2023 Category: Internal Medicine Source Type: research

UPLC-Q-TOF/MS-Based Serum Metabolomics Reveals Potential Anti-tumor Mechanism of Banxia Xiexin Decoction in Colorectal Cancer Mice
ConclusionBXD exerts partial protective effects on AOM/DSS-induced CRC by reducing inflammation, protecting organism immunity ability, and regulating amino acid metabolism. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - May 24, 2023 Category: Internal Medicine Source Type: research

Efficacy of Biejiajian Pill on Intestinal Microbiota in Patients with Hepatitis B Cirrhosis/Liver Fibrosis: A Randomized Double-Blind Controlled Trial
ConclusionBJJP had a certain regulatory effect on intestinal microbiota of patients with hepatitis B cirrhosis/liver fibrosis (ChiCTR1800016801). (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - May 24, 2023 Category: Internal Medicine Source Type: research

Comparing Arsenic-Containing Qinghuang Powder and Low-Intensity Chemotherapy in Elderly Patients with Acute Myeloid Leukemia
ConclusionsQHP and LIC had similar survival rates in eAML patients, but QHP had a lower myelosuppression incidence. Hence, QHP can be an alternative for eAML patients who do not tolerate LIC. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - May 24, 2023 Category: Internal Medicine Source Type: research