Chinese Journal of Integrative Medicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Pien Tze Huang Inhibits Migration and Invasion of Hepatocellular Carcinoma Cells by Repressing PDGFRB/YAP/CCN2 Axis Activity
ConclusionPZH restrained migration, invasion and epithelial-mesenchymal transition of HCC cells through repressing PDGFRB/YAP/CCN2 axis. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - August 10, 2022 Category: Internal Medicine Source Type: research

Cistanche Deserticola for Regulation of Bone Metabolism: Therapeutic Potential and Molecular Mechanisms on Postmenopausal Osteoporosis
AbstractOsteoporosis is a generalized disease of bone that leads to a loss of bone density and bone mass, destruction of bone microstructure, increased brittleness and therefore fracture. At present, the main treatment of Western medicine is drug therapy such as bisphosphonates, calcitriol, vitamin D, etc. However, long-term use of these drugs may bring some adverse reactions. Chinese herbal medicineCistanche deserticola could regulate bone metabolism by promoting osteoblast activity and inhibiting osteoclast activity with low toxicity and adverse reactions. Therefore,Cistanche deserticola has attracted increasing attentio...
Source: Chinese Journal of Integrative Medicine - August 5, 2022 Category: Internal Medicine Source Type: research

Cidan Capsule in Combination with Adjuvant Transarterial Chemoembolization Reduces Recurrence Rate after Curative Resection of Hepatocellular Carcinoma: A Multicenter, Randomized Controlled Trial
ConclusionsCidan Capsule in combination with TACE can reduce the incidence of early recurrence in HCC patients at high-risk of recurrence after radical hepatectomy and may be an appropriate option in postoperative anti-recurrence treatment. (Registration No. NCT 02253511) (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - August 1, 2022 Category: Internal Medicine Source Type: research

Head Acupuncture Plus Schuell ’s Language Rehabilitation for Post-Stroke Aphasia: A Systematic Review and Meta-Analysis of 32 Randomized Controlled Trials
ConclusionHA plus SLR was significantly associated with better language ability and higher effective rate for patients with post-stroke aphasia, and HA should be operated cautiously especially during acupuncture at eye and neck. (Registration No. CRD42020154475) (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 31, 2022 Category: Internal Medicine Source Type: research

Anti-inflammatory Effects of Ampelopsis Japonica Root on Contact Dermatitis in Mice
ConclusionA. japonica may be a new therapeutic agent with the potential to reduce or replace corticosteroids and its mechanisms are closely related to regulation of TNF- α production. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 31, 2022 Category: Internal Medicine Source Type: research

Transcutaneous Electrical Acupoint Stimulation Improves Postoperative Cognitive Function in Senior Patients Undergoing Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Trial
ConclusionApplication of TEAS in senior patients after VATS could reduce incidence of POCD and improve postoperative cognitive function. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 31, 2022 Category: Internal Medicine Source Type: research

Oral Arsenic-Containing Qinghuang Powder: A Potential Drug for Myelodysplastic Syndromes
AbstractQinghuang Powder (QHP), an oral arsenic, has become an effective drug in the treatment of myelodysplastic syndromes (MDS) in Xiyuan Hospital, China Academy of Chinese Medical Sciences for many years, and the action mechanism of the compound or active ingredient As2S2 of QHP has been elucidated. Considering the relatively safety, chemotherapy-free and convenient oral profile, QHP is widely used in the clinical treatment for MDS patients, especially for elderly patients. In this review, the authors document the efficacy and safety of oral arsenic-containing compound QHP in the treatment of MDS, with a special focus o...
Source: Chinese Journal of Integrative Medicine - July 31, 2022 Category: Internal Medicine Source Type: research

Baicalein Attenuates Severe Polymicrobial Sepsis via Alleviating Immune Dysfunction of T Lymphocytes and Inflammation
ConclusionBaicalein may be an effective immunomodulator that attenuates overwhelming inflammatory responses in severe abdominal sepsis. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 31, 2022 Category: Internal Medicine Source Type: research

Meranzin Hydrate Improves Depression-Like Behaviors and Hypomotility via Ghrelin and Neurocircuitry
ConclusionsMH accounts for part of AP effects of parent formula CSP in acute FS rats, mainly via ghrelin-related shared regulation coupled to BOLD signals in brain areas. This novel functionally connection of HTB following acute stress, treatment, and regulation highlights anti-depression unified theory. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 26, 2022 Category: Internal Medicine Source Type: research

Quality Evaluation and Reporting Specification for Real-World Studies of Traditional Chinese Medicine
AbstractIn recent years, the real-world studies (RWS) have attracted extensive attention, and the real-world evidence (RWE) has been accepted to support the drug development in China and abroad. However, there is still a lack of standards for the evaluation of the quality of RWE. It is necessary to formulate a quality evaluation and reporting specification for RWE especially in traditional Chinese medicine (TCM). To this end, under the guidance of China Association of Chinese Medicine, the Quality Evaluation and Reporting Specification for Real-World Evidence of Traditional Chinese Medicine (QUERST) Group, including 24 exp...
Source: Chinese Journal of Integrative Medicine - July 18, 2022 Category: Internal Medicine Source Type: research

Shexiang Baoxin Pill Regulates Intimal Hyperplasia, Migration, and Apoptosis after Platelet-Derived Growth Factor-BB-Stimulation of Vascular Smooth Muscle Cells via miR-451
ConclusionSXBXW regulated proliferation, migration and apoptosis via activation of miR-451 through ATF2, p53 and Ywhaz in PDGF-BB-stimulated VSMCs. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 15, 2022 Category: Internal Medicine Source Type: research

Efficacy and Safety of Bushen Huoxue Formula in Patients with Discogenic Low-Back Pain: A Double-Blind, Randomized, Placebo-Controlled Trial
ConclusionBSXHF combined with lumbar traction can significantly improve the clinical symptoms including pain intensity, functionality, muscle tone, and lumbar spine mobility in DLBP patients. (Registration No. ChiCTR1900027777). (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 15, 2022 Category: Internal Medicine Source Type: research

Involvement of Interleukin-1 β/Insulin-Like Growth Factor 1 in Ameliorating Effects of Electroacupuncture on Myocardial Fibrosis Induced by Essential Hypertension
ConclusionEA at bilateral PC 6 could ameliorate cardiac fibrosis in SHRs, which might be mediated by regulation of 1L-1 β/IGF-1-TGF- β 1-MMP9 pathway. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 15, 2022 Category: Internal Medicine Source Type: research

Shenmai Injection Improves Hypertensive Heart Failure by Inhibiting Myocardial Fibrosis via TGF- β 1/Smad Pathway Regulation
ConclusionMyocardial fibrosis is the main pathological manifestation of hypertensive heart failure, and Shenmai Injection could inhibit myocardial fibrosis and effectively improve heart failure by regulating TGF- β 1/Smad signaling pathway. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - July 15, 2022 Category: Internal Medicine Source Type: research

Indian Traditional Treatments for Psoriasis: A Critical Appraisal of Available Evidence Supporting Efficacy
AbstractPsoriasis is an immune-mediated chronic inflammatory skin disease with multifactorial etiology. Although many drugs are available in biomedicine for the treatment of psoriasis, these therapies are aimed at controlling the disease rather than a complete cure. In India, traditional systems of medicines like Ayurveda, Unani, Siddha, and homeopathy are practised for psoriasis. This review examines data from 17 selected studies supporting the clinical efficacy of medical management approaches from these systems using outcome indicators employed in clinical practice and research for psoriasis. All studies reported good i...
Source: Chinese Journal of Integrative Medicine - July 12, 2022 Category: Internal Medicine Source Type: research