Natriuretic Peptides as a Prognostic Marker for Delirium in Cardiac Surgery-A Pilot Study.
Conclusions: We found a positive correlation between delirium and preoperative plasma levels of ANP and NT-proCNP. A well-powered and prospective study might identify NPs as biomarkers indicating the risk of delirium and postoperative cognitive decline in patients at risk for postoperative delirium. PMID: 32471143 [PubMed - as supplied by publisher] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 27, 2020 Category: Universities & Medical Training Authors: Saller T, Peterss S, Scheiermann P, Eser-Valeri D, Ehler J, Bruegger D, Chappell D, Kofler O, Hagl C, Hofmann-Kiefer K Tags: Medicina (Kaunas) Source Type: research

Reasons for and Facilitating Factors of Medical Malpractice Complaints. What Can Be Done to Prevent Them?
Conclusions. Regarding the dysfunctions in the doctor-patient relationship frequently claimed by patients, the authors concluded that doctors need special undergraduate training and periodic updating during their practice for them to be able to adequately address the challenges of interacting with their patients. PMID: 32471166 [PubMed - as supplied by publisher] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 27, 2020 Category: Universities & Medical Training Authors: Hanganu B, Iorga M, Muraru ID, Ioan BG Tags: Medicina (Kaunas) Source Type: research

Effects of Cesarean Section and Vaginal Delivery on Abdominal Muscles and Fasciae.
Abstract Background and objectives: Possible disorders after delivery may interfere with the quality of life. The aim of this study was to ascertain whether abdominal muscles and fasciae differ in women depending on whether they experienced transverse cesarean section (CS) or vaginal delivery (VA) in comparison with healthy nulliparous (NU). Materials and methods: The thicknesses of abdominal muscles and fasciae were evaluated by ultrasound in 13 CS, 10 VA, and 13 NU women (we examined rectus abdominis (RA); external oblique (EO); internal oblique (IO); transversus abdominis (TrA); total abdominal muscles (TAM = E...
Source: Medicina (Kaunas) - May 27, 2020 Category: Universities & Medical Training Authors: Fan C, Guidolin D, Ragazzo S, Fede C, Pirri C, Gaudreault N, Porzionato A, Macchi V, De Caro R, Stecco C Tags: Medicina (Kaunas) Source Type: research

Proactive COVID-19 Infection Prevention Measures in a Hyperbaric Oxygen Therapy Center.
Abstract Since the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China in December 2019 and its subsequent global spread, Taiwan has been combatting this pandemic. COVID-19 is caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). As SARS-CoV-2 can be transmitted through droplets and aerosols, we cannot ignore the risk of transmission during hyperbaric oxygen therapy (HBOT). Our hyperbaric oxygen therapy center prioritizes preventing the spread of COVID-19 and maintaining operation for the patients during the pandemic. The aim of this article is to share the protoc...
Source: Medicina (Kaunas) - May 27, 2020 Category: Universities & Medical Training Authors: Lo JJ, Wang SC, Lee HY, Lee SS, Lee HC, Hung CT, Huang SH Tags: Medicina (Kaunas) Source Type: research

Incidence of Severe Chronic Neutropenia in South Korea and Related Clinical Manifestations: A National Health Insurance Database Study.
CONCLUSIONS: This nationwide population-based epidemiological study showed that incidence of SCN is higher in pediatrics and middle-aged women. As progression to hematologic malignancy was significantly higher in the age of in 45-49 year olds, careful follow-up is necessary in this group. However, since this study lacks the molecular information, these finding need to be interpreted with great caution. PMID: 32471206 [PubMed - as supplied by publisher] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 27, 2020 Category: Universities & Medical Training Authors: Lee N, Lee BC Tags: Medicina (Kaunas) Source Type: research

Relationship between Implant Length and Implant Stability of Single-Implant Restorations: A 12-Month Follow-Up Clinical Study.
Abstract Background and Objectives: Implant stability in vivo is contingent on multiple factors, such as bone structure, instrument positioning and implant surface modifications, implant diameter, and implant length. Resonance-frequency analysis is considered a non-invasive, reliable, predictable, and objective method by which to evaluate implant stability, due to its correlation with bone-to-implant contact. The purpose of this study was to evaluate the effect of implant length on the primary and secondary stability of single-implant crown rehabilitations, as measured by resonance-frequency analysis at different ...
Source: Medicina (Kaunas) - May 27, 2020 Category: Universities & Medical Training Authors: Aragoneses JM, Aragoneses J, Brugal VA, Gomez M, Suarez A Tags: Medicina (Kaunas) Source Type: research

Autoimmune Thyroid Disease is Associated with a Lower Prevalence of Diabetic Retinopathy in Patients with Type 1 Diabetic Mellitus.
Conclusions: Patients with DM1 and AITD were metabolically better balanced, as evidenced by a significantly lower SBP, percentage of HbA1c and TG, as well as significantly higher HDL-cholesterol in this group. Patients with DM1 and AITD were significantly less likely to have NPDR than the control group. PMID: 32466561 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 26, 2020 Category: Universities & Medical Training Authors: Stefanowicz-Rutkowska MM, Matuszewski W, Bandurska-Stankiewicz EM Tags: Medicina (Kaunas) Source Type: research

Stress in the Volunteer Caregiver: Human-Centric Technology Can Support Both Caregivers and People with Dementia.
Conclusion: Since professional caregivers have access to technological resources that our home-based caregivers lack, one might logically conclude that we should transfer technology used by professionals to those with dementia. However, great caution needs to be in place before we take that step. Successful technology should address the human experience as home-based caregivers try to use new technologies. Human-centric technology addresses the needs of both people with dementia and the home-based caregiver. PMID: 32466618 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 26, 2020 Category: Universities & Medical Training Authors: Huelat B, Pochron ST Tags: Medicina (Kaunas) Source Type: research

Submuscular and Pre-Pectoral ADM Assisted Immediate Breast Reconstruction: A Literature Review.
Conclusions: Several authors have recently reported positive results. Nevertheless, an increased complications' rate has been reported by other authors. Higher cost compared to not-ADM-assisted breast reconstruction is another concern. PMID: 32466619 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 26, 2020 Category: Universities & Medical Training Authors: Cuomo R Tags: Medicina (Kaunas) Source Type: research

Phacoemulsification Induced Changes of Choroidal Thickness in Eyes with Age-Related Macular Degeneration.
Conclusion: Uneventful phacoemulsification may induce changes in the posterior eye segment. An increase in CT and FRT was observed in both groups one month after the surgery. However, three months after surgery, CT changes were different in both groups, while FRT decreased in both groups. CT changes negatively associated with age in the No-AMD group and with AL in the AMD eyes. These postoperative changes in the choroid and retina may not only lead to the late-onset pseudophakic cystoid macular edema but also to progression of AMD. PMID: 32455884 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 22, 2020 Category: Universities & Medical Training Authors: Gudauskienė G, Povilaitytė I, Šepetauskienė E, Žaliūnienė D Tags: Medicina (Kaunas) Source Type: research

The Diagnostic-Therapeutic Care Pathway in Psoriasis: Towards ISO 9001:2015 Certification.
Conclusions: In qualifying for and achieving the ISO Quality Management System (QMS) certification we were heartened to realize that our basic methodology and approach were fit for purpose. The implementation of the ISO QMS helped us to reorganize our priorities by placing the patient at the center of the process and raising awareness that Pso is not just a skin disease. PMID: 32455972 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 22, 2020 Category: Universities & Medical Training Authors: Veronese F, Graziola F, Cammarata E, Andreassi M, Mazzoletti V, Taglietti C, Navarra G, Savoia P, Tiberio R Tags: Medicina (Kaunas) Source Type: research

Sclerotherapy of Vascular Malformations in the Oral Cavity-Minimizing Postoperative Morbidity.
The objective of this study was to assess the efficacy and morbidity of sclerotherapy for the treatment of VMs in the oral and perioral area. Special attention was given to factors that may contribute to minimizing postoperative morbidity. Data from 25 patients (32 lesions) with oral VMs submitted to sclerotherapy with monoethanolamine oleate (EAO) were included. A structured form was used to collect data. An arbitrary score was determined to evaluate postoperative morbidity. Each of the following signs or symptoms received one point: pain, swelling, hematoma, ulceration, erythema, transient numbness, and transient itching...
Source: Medicina (Kaunas) - May 22, 2020 Category: Universities & Medical Training Authors: Zeevi I, Chaushu G, Alterman M, Chaushu L Tags: Medicina (Kaunas) Source Type: research

Role of a Brief Intensive Observation Area with a Dedicated Team of Doctors in the Management of Acute Heart Failure Patients: A Retrospective Observational Study.
Conclusions: Data from our study show that a dedicated area of the ER, such as the OBI, has progressively allowed a change in the treatment path of the patient, where the aim is no longer to admit the patient for processing but to treat the patient first and then, if necessary, admit or refer. This has resulted in very good feedback on patient stabilization and has resulted in a better management of beds, reduced admission rates, and reduced use of high intensity care beds. PMID: 32455837 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 21, 2020 Category: Universities & Medical Training Authors: Savioli G, Ceresa IF, Manzoni F, Ricevuti G, Bressan MA, Oddone E Tags: Medicina (Kaunas) Source Type: research

Actual Nutrition and Dietary Supplementation in Lithuanian Elite Athletes.
Conclusions: Athletes consume insufficient carbohydrates, vitamin D, calcium, polyunsaturated fatty acids, omega-3 and omega-6 fatty acids and too much fat, saturated fatty acids, cholesterol, and they use proteins irrationally. Sport nutritionists should also focus on the risk of malnutrition for female athletes. Nutritional supplements partially offset macronutrient and micronutrient deficiency. Nevertheless, the effect of food supplements on the body composition of athletes is too small compared to the normal diet. Athletes ought to prioritize the formation of eating habits and only then use supplements. PMID: 3244...
Source: Medicina (Kaunas) - May 20, 2020 Category: Universities & Medical Training Authors: Baranauskas M, Jablonskienė V, Abaravičius JA, Stukas R Tags: Medicina (Kaunas) Source Type: research

The Role of Laparoscopic Ultrasonography in the Evaluation of Suspected Choledocholithiasis. A Single-Center Experience.
Abstract Background and objectives: Opinions differ regarding the optimal diagnostic methods for patients with suspected choledocholithiasis. The aim of this study was to assess the diagnostic accuracy of laparoscopic ultrasonography (LUS) and compare it to pre-operative magnetic resonance cholangio-pancreatography (MRCP); Materials and Methods: In all patients with suspected choledocholithiasis LUS was performed during laparoscopic cholecystectomy to evaluate biliary stones. According to availability, part of the patients had pre-operative MRCP. Data for diagnostic accuracy and main outcomes were collected prospe...
Source: Medicina (Kaunas) - May 20, 2020 Category: Universities & Medical Training Authors: Atstupens K, Mukans M, Plaudis H, Pupelis G Tags: Medicina (Kaunas) Source Type: research

Relationship between Vitamin Deficiencies and Co-Occurring Symptoms in Autism Spectrum Disorder.
Abstract Recently, connections have been made between feeding and eating problems and autism spectrum disorder (ASD) and between autism pathophysiology and diet issues. These could explain some of the mechanisms which have not yet been discovered or are not sufficiently characterized. Moreover, there is an increased awareness for micronutrients in ASD due to the presence of gastrointestinal (GI) problems that can be related to feeding issues. For example, levels of vitamins B1, B6, B12, A and D are often reported to be low in ASD children. Thus, in the present mini review we focused on describing the impact of som...
Source: Medicina (Kaunas) - May 20, 2020 Category: Universities & Medical Training Authors: Robea MA, Luca AC, Ciobica A Tags: Medicina (Kaunas) Source Type: research

Are Force Enhancement after Stretch and Muscle Fatigue Due to Effects of Elevated Inorganic Phosphate and Low Calcium on Cross Bridge Kinetics?
Conclusions: This suggests that in fatigue, there is an accumulation of attached but low-force cross bridges that cannot be the result of the combined action of reduced Ca2+ or increased Pi alone, but is probably due to a combination of factors that change during fatigue. PMID: 32443826 [PubMed - as supplied by publisher] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 20, 2020 Category: Universities & Medical Training Authors: Degens H, Jones DA Tags: Medicina (Kaunas) Source Type: research

COVID-19 Pandemic and Telephone Triage before Attending Medical Office: Problem or Opportunity?
Abstract During the COVID-19 emergency, the medical operating protocols have been largely modified for reducing any type of contamination risk, for working in a safe way and for making the patient feel in a safe environment. Telemedicine, smart phones and apps could represent important devices for the community, in order to prevent virus trasmission and to perform quick diagnosis and management at medical offices. This manuscript could be useful for clinicians with regard to the current state of the effectiveness of the telephone triage in this COVID-19 epidemic period. Therefore, it could be an important starting...
Source: Medicina (Kaunas) - May 20, 2020 Category: Universities & Medical Training Authors: Cervino G, Oteri G Tags: Medicina (Kaunas) Source Type: research

Pleomorphic Adenoma of External Auditory Canal: Case Report of First Endoscopic Resection and Literature Review.
Abstract Ceruminous pleomorphic adenoma is a very rare, mostly benign tumor originating from the ceruminal glands in the external auditory canal. Histologically, it is a mixed tumor with epithelial and stromal parts of different proportions, and is recognized today by the World Health Organization (WHO) as a ceruminous adenoma. Similar to the pleomorphic adenoma of salivary glands, recurrence or malignant degeneration with cellular atypia and metastasis can occur on rare occasions. Here, we describe an 87-year old female patient with a growing spherical mass in the right external auditory canal. After exclusive en...
Source: Medicina (Kaunas) - May 20, 2020 Category: Universities & Medical Training Authors: Beckmann S, Dettmer MS, Caversaccio MD, Giger R, Anschuetz L Tags: Medicina (Kaunas) Source Type: research

Analysis of Multiple Risk Factors for Seronegative Rate of Anti-Tick-Borne Encephalitis Virus Immunization in Human Serum.
Conclusions: This study demonstrates that the vaccination schedule should be reevaluated. The extension of the interval of booster immunization is risky and all subjects should be surrounded by care consisting of more frequent monitoring of serum antibodies by personalized schedule to adjust the frequency of subsequent doses of booster vaccination. PMID: 32443896 [PubMed - as supplied by publisher] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 20, 2020 Category: Universities & Medical Training Authors: Janik M, Płaczkowska S, Woźniak M, Bil-Lula I Tags: Medicina (Kaunas) Source Type: research

Inherited Risk Factors of Thromboembolic Events in Patients with Primary Nephrotic Syndrome.
Conclusions. These findings suggest that genetic testing for inherited thrombophilia in NS could play an important role in detecting high-risk patients that warrant prophylactic anticoagulation. PMID: 32438633 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 19, 2020 Category: Universities & Medical Training Authors: Ismail G, Obrișcă B, Jurubiță R, Andronesi A, Sorohan B, Hârza M Tags: Medicina (Kaunas) Source Type: research

Artificial Neural Network and Cox Regression Models for Predicting Mortality after Hip Fracture Surgery: A Population-Based Comparison.
This study purposed to validate the accuracy of an artificial neural network (ANN) model for predicting the mortality after hip fracture surgery during the study period, and to compare performance indices between the ANN model and a Cox regression model. A total of 10,534 hip fracture surgery patients during 1996-2010 were recruited in the study. Three datasets were used: a training dataset (n = 7,374) was used for model development, a testing dataset (n = 1,580) was used for internal validation, and a validation dataset (1580) was used for external validation. Global sensitivity analysis also was performed to evaluate the...
Source: Medicina (Kaunas) - May 19, 2020 Category: Universities & Medical Training Authors: Chen CY, Chen YF, Chen HY, Hung CT, Shi HY Tags: Medicina (Kaunas) Source Type: research

Determination of Referential Rates for Optical Coherence Tomography and Optical Coherence Tomography Angiography Flow Deficits in the Macular Choriocapillaris in Ophthalmologically Healthy Children.
Conclusions: The thinnest RNFL layers were on the temporal and nasal sides. FD% values in the C1, C2.5, and R1.5 sectors were similar between the 3 × 3-mm and 6 × 6-mm scans. The negative moderate correlations between AxL and FD% were found in all C1, C2.5, C5, R1.5, and R2.5 sectors of the 6 × 6-mm scans. Further prospective studies are needed to determine more accurate normative references for children's OCT parameters. PMID: 32429361 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 16, 2020 Category: Universities & Medical Training Authors: Bakstytė V, Šniurevičiūtė L, Šimienė E, Skruodytė J, Janulevičienė I Tags: Medicina (Kaunas) Source Type: research

Clinical Characteristics of Mitochondrial DNA Copy Number in Osteonecrosis of the Femoral Head.
Conclusions: in this study, we demonstrated that mtDNA-CN might be a significant marker for predicting clinical characteristics in ONFH. PMID: 32429397 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 16, 2020 Category: Universities & Medical Training Authors: Lee SW, Lee KJ, Kim BS, Kwon HJ, Lee JH Tags: Medicina (Kaunas) Source Type: research

Herbal Preparations of Medical Cannabis: A Vademecum for Prescribing Doctors.
Rio A Abstract Cannabis has been used for centuries for therapeutic purposes. In the last century, the plant was demonized due to its high abuse liability and supposedly insufficient health benefits. However, recent decriminalization policies and new scientific evidence have increased the interest in cannabis therapeutic potential of cannabis and paved the way for the release of marketing authorizations for cannabis-based products. Although several synthetic and standardized products are currently available on the market, patients' preferences lean towards herbal preparations, because they are easy to handle and s...
Source: Medicina (Kaunas) - May 15, 2020 Category: Universities & Medical Training Authors: Brunetti P, Pichini S, Pacifici R, Busardò FP, Del Rio A Tags: Medicina (Kaunas) Source Type: research

Could FeNO Predict Asthma in Patients with House Dust Mites Allergic Rhinitis?
Abstract Background and Objectives: The evolution of allergic rhinitis to asthma is a part of "atopic march". The aim of this study was to analyze possible predictive markers for asthma occurrence in patients with allergic rhinitis to house dust mites (HDM). Materials and Methods: Fifty-eight patients with persistent allergic rhinitis (PAR) were included. The clinical, biological evaluation and fractionated exhaled nitric oxide (FeNO) measurement were performed at enrolment. The patients were clinically evaluated after one year to determine asthma occurrence. Results: The severity of rhinitis symptoms, l...
Source: Medicina (Kaunas) - May 14, 2020 Category: Universities & Medical Training Authors: Muntean IA, Bocsan IC, Vesa S, Miron N, Nedelea I, Buzoianu AD, Deleanu D Tags: Medicina (Kaunas) Source Type: research

Serum Potassium Levels at Hospital Discharge and One-Year Mortality among Hospitalized Patients.
Conclusion: The association between discharge serum potassium and one-year mortality after hospital discharge had a U-shaped distribution and was independent of admission serum potassium. Favorable survival outcomes occurred when discharge serum potassium was strictly within the range of 4.0-4.4 mEq/L. PMID: 32423140 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 14, 2020 Category: Universities & Medical Training Authors: Thongprayoon C, Cheungpasitporn W, Thirunavukkarasu S, Petnak T, Chewcharat A, Bathini T, Vallabhajosyula S, Mao MA, Erickson SB Tags: Medicina (Kaunas) Source Type: research

Should Autism Spectrum Conditions Be Characterised in a More Positive Way in Our Modern World?
Abstract In a special issue that focuses on complex presentations related to Autism, we ask the question in this editorial whether an Autism Spectrum Condition without complexity is a disorder, or whether it represents human diversity? Much research into Autism Spectrum Conditions (ASCs) over the years has focused on comparisons between neuro-typical people and people with Autism Spectrum Conditions. These comparisons have tended to draw attention to 'deficits' in cognitive abilities and descriptions of behaviours that are characterised as unwanted. Not surprisingly, this is reflected in the classification systems...
Source: Medicina (Kaunas) - May 13, 2020 Category: Universities & Medical Training Authors: Wright B, Spikins P, Pearson H Tags: Medicina (Kaunas) Source Type: research

Effects of Khat on Surface Roughness and Color of Feldspathic and Zirconia Porcelain Materials under Simulated Oral Cavity Conditions.
Conclusion: KH significantly affected both surface parameter and color of glazed or polished porcelain materials and natural teeth. PMID: 32414190 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 13, 2020 Category: Universities & Medical Training Authors: Moaleem MMA, AlSanosy R, Ahmari NMA, Shariff M, Alshadidi AA, Alhazmi HA, Khalid A Tags: Medicina (Kaunas) Source Type: research

Hypersensitivity Reactions to Monoclonal Antibodies in Children.
Abstract Biologic drugs are widely used in pediatric medicine. Monoclonal antibodies (mAbs) in particular are a therapeutic option for rheumatic, autoinflammatory and oncologic diseases. Adverse drug reactions and hypersensitivity reactions (HSR) to mAbs may occur in children. Clinical presentation of HSRs to mAbs can be classified according to phenotypes in infusion-related reactions, cytokine release syndrome, both alpha type reactions and type I (IgE/non-IgE), type III, and type IV reactions, all beta-type reactions. The aim of this review is to focus on HSRs associated with the most frequent mAbs in childhood,...
Source: Medicina (Kaunas) - May 12, 2020 Category: Universities & Medical Training Authors: Mori F, Saretta F, Bianchi A, Crisafulli G, Caimmi S, Liotti L, Bottau P, Franceschini F, Paglialunga C, Ricci G, Santoro A, Caffarelli C Tags: Medicina (Kaunas) Source Type: research

Value of Routine Flexible Sigmoidoscopy and Potential Predictive Factors for Colonic Ischemia after Open Ruptured Abdominal Aortic Aneurysm Repair.
Conclusions: flexible sigmoidoscopy can identify patients being at higher risk of mortality after open rAAA repair. The postoperative lactate and hemoglobin were found to be independent risk factors for the development of CI after open rAAA repair. Further larger studies are warranted to demonstrate these findings. PMID: 32403234 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 11, 2020 Category: Universities & Medical Training Authors: Urbonavicius S, Feuerhake IL, Srinanthalogen R, Urbonavicius M, Baltrunas T, Grøndal NF, Randsbæk F Tags: Medicina (Kaunas) Source Type: research

Synchronous Multiple Breast Cancers-Do We Need to Reshape Staging?
Conclusions: For synchronous breast tumors, the current Tumor-Node-Metastasis (TNM) staging system ignores not only the histopathological and immunohistochemical characteristics of the secondary foci, but also their size. When secondary lesions are more aggressive or their cumulative mass is significantly bigger than that of the index tumor, the treatment plan should be adapted accordingly. We believe that information obtained from examining secondary foci in synchronous breast cancer and assessment of the cumulative tumoral mass should be reflected in the final staging and definitive treatment. The clinical benefit of sta...
Source: Medicina (Kaunas) - May 11, 2020 Category: Universities & Medical Training Authors: Onisâi M, Dumitru A, Iordan I, Aliuș C, Teodor O, Alexandru A, Gheorghiță D, Antoniac I, Nica A, Mihăilescu AA, Grădinaru S Tags: Medicina (Kaunas) Source Type: research

Use of Glycated Hemoglobin (A1c) as a Biomarker for Vascular Risk in Type 2 Diabetes: Its Relationship with Matrix Metalloproteinases-2, -9 and the Metabolism of Collagen IV and Elastin.
Conclusions: A set of three tested markers (MMP-2, MMP-9, and AEAbs IgA) showed that vascular damages from preceding long-term hyperglycemia begin to dominate at HbA1c values ≥7.5%, which is the likely cut-point to predict increased vascular risk. PMID: 32403389 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 11, 2020 Category: Universities & Medical Training Authors: Kostov K, Blazhev A Tags: Medicina (Kaunas) Source Type: research

Stroke, Dementia, and Atrial Fibrillation: From Pathophysiologic Association to Pharmacological Implications.
Abstract The impact of stroke and dementia on disability and death is a major contemporary health issue [...]. PMID: 32397581 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 10, 2020 Category: Universities & Medical Training Authors: Russo V, Vio R, Proietti R Tags: Medicina (Kaunas) Source Type: research

Acute Effects of a Single Football Training or Match on Passive Hip Rotation Range of Motion in Semi-Professional Football Players: A Pilot Study.
CONCLUSIONS: Despite the small sample size of the present study, the findings indicate that a single football activity leads to significant changes in hip rotation ROM in players with restricted bilateral hip external-rotation ROM. However, these changes did not reach reference cut-off scores. PMID: 32397596 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 10, 2020 Category: Universities & Medical Training Authors: De-la-Cruz-Torres B, Abuín-Porras V, Blanco-Morales M, de-la-Cueva-Reguera M, Calvo-Lobo C, López-López D, Romero-Morales C Tags: Medicina (Kaunas) Source Type: research

Interdisciplinary Approach to the Temporomandibular Joint Osteoarthritis-Review of the Literature.
Conclusions: Osteoarthritis is an inflammatory, age-related, chronic and progressive degenerative joint disease. Magnetic resonance imaging (MRI) and cone-beam computed tomography (CBCT), together with clinical symptoms, play significant roles in TMJOA diagnosis. Current MRI techniques seem to be clinically useful for assessment of bony changes in temporomandibular joint (TMJ) disorders. Treatment of TMJOA requires a complex, interdisciplinary approach. TMJOA treatment includes the cooperation of physiotherapists, rheumatologists, gnathologists, orthodontists and quite often also maxillofacial surgeons and prosthodontists....
Source: Medicina (Kaunas) - May 9, 2020 Category: Universities & Medical Training Authors: Derwich M, Mitus-Kenig M, Pawlowska E Tags: Medicina (Kaunas) Source Type: research

Reasons for Breastfeeding Cessation in the First Year after Childbirth in Lithuania: A Prospective Cohort Study.
Abstract Objectives: to identify the main reasons of breastfeeding cessation in Lithuania and if there is a link between the length of maternity leave and breastfeeding cessation. Methods: a prospective questionnaire study was conducted in a tertiary hospital from 2016 to 2017. The sample size included 449 women. Results: a total of 41% (n = 123) of respondents weaned off by 6 months after birth, and 57.8% (n = 173) between 6 months and 1 year. During the first few days after delivery, mothers did not breastfeed their infants mainly due to shortage of milk (n = 10; 40%) or separation from their baby due to infant ...
Source: Medicina (Kaunas) - May 9, 2020 Category: Universities & Medical Training Authors: Zitkute V, Snieckuviene V, Zakareviciene J, Pestenyte A, Jakaite V, Ramasauskaite D Tags: Medicina (Kaunas) Source Type: research

Siesta and Risk for Ischemic Stroke: Results from a Case-Control Study.
Conclusions: Siesta was associated with a reduced risk for the occurrence of ischemic stroke. Large prospective longitudinal studies should be conducted to verify the protective effect of siesta on stroke. PMID: 32392748 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 7, 2020 Category: Universities & Medical Training Authors: Mohammad Y Tags: Medicina (Kaunas) Source Type: research

Resolution of Fetal Hydrops Dependent on Sustained Fetal Supraventricular Tachycardia after Digoxin Therapy.
We present a special case of fetal supraventricular tachycardia detected at 34 weeks gestation. Fetal hydrops was noted on ultrasound upon admission. Normal fetal heart rate was maintained for three weeks by maternal administration of digoxin. A live infant was delivered via caesarian section at 37 weeks gestation. This clinical case demonstrated that pharmacological treatment can be effective and helps to prolong pregnancy safely. PMID: 32392830 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 7, 2020 Category: Universities & Medical Training Authors: Maciuleviciute A, Semenaite M, Gintautas V, Maciuleviciene R, Puodziukynas A, Savukyne E Tags: Medicina (Kaunas) Source Type: research

Sarcoma as Second Cancer in a Childhood Cancer Survivor: Case Report, Large Population Analysis and Literature Review.
We present a 9-year-old male who survived embryonal hepatoblastoma diagnosed at 22 months of age. At 4.5 years of age, he presented with a non-metastatic primitive neuroectodermal tumor (PNET) of the left submandibular area. He has no evidence of recurrence of either cancer for 51 months after finishing all chemotherapy and radiotherapy. We used the Surveillance, Epidemiology, and End Results (SEER) database to identify the current rate of second sarcomas in pediatric cancer survivors. Our literature review and large population analysis emphasize the impact of sarcoma as a second malignancy and provide help to physicians c...
Source: Medicina (Kaunas) - May 7, 2020 Category: Universities & Medical Training Authors: Nguyen TH, Makena MR, Yavvari S, Kaur M, Pham T, Urias E, Panapitiya N, Al-Rahawan MM Tags: Medicina (Kaunas) Source Type: research

Influence of a Foot Insole for a Down Syndrome Patient with a Flat Foot: A Case Study.
Conclusions: As the angle of the knee joint decreased during the gait, it was considered that the stability of the knee joint improved by inserting the insole. In particular, there was a large difference in the tibial internal rotation angle when the insole was inserted. It is thus hypothesized that the insole contributes to the rotational stability of the knee joint. This study suggests that knee stability may improve and that gait becomes more stable when a Down syndrome patient with a flat foot wears an insole. PMID: 32384597 [PubMed - as supplied by publisher] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 6, 2020 Category: Universities & Medical Training Authors: Endo Y, Kanai Y, Yozu A, Kobayashi Y, Fukaya T, Mutsuzaki H Tags: Medicina (Kaunas) Source Type: research

Effects of 12 Weeks of Resistance Training on Cardiovascular Risk Factors in School Adolescents.
al AC Abstract Background and objectives: The practice of physical exercise, especially resistance exercise, is important for the treatment and/or prevention of cardiovascular risk factors in adult individuals. However, there are few studies on its effects on adolescent individuals. Therefore, the aim of the present study was to evaluate the effects of applying a 12-week resistance training program on cardiovascular risk factors in adolescents. Materials and Methods: Thus, 122 adolescents aged 13-16 years of both genders participated in the study from school in the city of Lagarto, Sergipe (SE), Brazil, divided in...
Source: Medicina (Kaunas) - May 6, 2020 Category: Universities & Medical Training Authors: Rosa Santos LD, Araujo SS, Vieira EFDS, Estevam CDS, Santos JLD, Wichi RB, Lima FB, Carvalho CRO, Aidar FJ, Marçal AC Tags: Medicina (Kaunas) Source Type: research

An investigation into Video Game Addiction in Pre-Adolescents and Adolescents: A Cross-Sectional Study.
CONCLUSION: Males are pathological gamblers more so than females and spend more time playing video games. An increase in Daily game frequency or Daily gaming time implicates an increase in video game addictions, while an increase in Education level, which generally corresponds to a greater age, implicates a decrease in game addiction. Finally, we observed that the correlations obtained between the Polythetic Partial GAS score with the independent variables such as Age, Gender, Education level, Daily gaming time (hours), and Daily game frequency were analogous to the significant correlations obtained with the Monothetic GAS...
Source: Medicina (Kaunas) - May 6, 2020 Category: Universities & Medical Training Authors: Esposito MR, Serra N, Guillari A, Simeone S, Sarracino F, Continisio GI, Rea T Tags: Medicina (Kaunas) Source Type: research

Cognitive Health of Nonagenarians in Southern Italy: A Descriptive Analysis from a Cross-Sectional, Home-Based Pilot Study of Exceptional Longevity (Cilento Initiative on Aging Outcomes Or CIAO).
Conclusion: In the Cilento Region of Southern Italy, NCs seemed to have good cognitive status when compared to younger cohabitants aging 50-65 years without significant differences in oxidative stress markers or APOE genotype. These results might be related to optimal adherence to the Mediterranean diet, although other lifestyle factors and positive personality traits may also contribute to their healthy aging. Further studies on a larger population should be performed to confirm the results of this pilot study. PMID: 32380778 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - May 5, 2020 Category: Universities & Medical Training Authors: Pizza V, Antonini P, Marino R, D'Arena G, Lucibello SG, Rizzo M, Brenner DA, Jeste DV, Somma SD Tags: Medicina (Kaunas) Source Type: research

Diffusion-Weighted Magnetic Resonance Imaging as a Noninvasive Parameter for Differentiating Benign and Malignant Intraperitoneal Collections.
Abstract Background and Objective: The imaging differentiation of benign from malignant intraperitoneal collections (IPCs) relies on the tumoral morphological modifications of the peritoneum, which are not always advocating for malignancy. We aimed to assess ascitic fluid with the apparent diffusion coefficient (ADC) to determine non-invasive, stand-alone, differentiation criteria for benign and malignant intraperitoneal effusions. Materials and Methods: Sixty-one patients with known IPCs who underwent magnetic resonance examinations for reasons such as tumor staging, undetermined abdominal mass and disease follow...
Source: Medicina (Kaunas) - May 1, 2020 Category: Universities & Medical Training Authors: Ștefan PA, Csutak C, Lebovici A, Rusu GM, Mihu CM Tags: Medicina (Kaunas) Source Type: research

Management of Hypothyroidism in Patients with Acute Myocardial Infarction.
Conclusion: A history of hypothyroidism and the degree of TSH elevation seem to guide the management of hypothyroidism in patients with AMI. The clinical effect of correcting hypothyroidism in this setting requires further evaluation. PMID: 32353935 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 28, 2020 Category: Universities & Medical Training Authors: Eagan D, Spencer-Bonilla G, Maraka S, Aggarwal M, Singh Ospina N Tags: Medicina (Kaunas) Source Type: research

Evaluation of TP-E Interval and TP-E/QT Ratio in Panic Disorder.
This study aimed to evaluate ventricular repolarization parameters in patients with panic disorder. Materials and Methods: In total, 40 patients with panic disorder, diagnosed using the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria, were included in the study group. The control group comprised of 50 age- and sex-matched healthy individuals. A standard 12 lead electrocardiogram was recorded on all participants, and heart rate, QT interval, QRS duration, Tp-e interval, and Tp-e/QT ratio were measured. Results: QRS durations and QT intervals were similar in the study and control groups. Compared to th...
Source: Medicina (Kaunas) - April 28, 2020 Category: Universities & Medical Training Authors: Afsin A, Asoğlu R, Orum MH, Cicekci E Tags: Medicina (Kaunas) Source Type: research

Open-Healing Socket Preservation with a Novel Dense Polytetrafluoroethylene (dPTFE) Membrane: A Retrospective Clinical Study.
Conclusions: The use of the examined new dPTFE membrane consistently led to the preservation of hard tissue in the extraction sites. PMID: 32354120 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 28, 2020 Category: Universities & Medical Training Authors: Zafiropoulos GG, Kačarević ZP, Qasim SSB, Trajkovski B Tags: Medicina (Kaunas) Source Type: research

Assessment of the Relationship between Selected Factors and Stress-Coping Strategies in Handcyclists-A Preliminary Study.
Conclusions: Highly educated cyclists with short-lasting disability, damage to the lower spine section or amputations tend to cope better with stress than other study participants. PMID: 32349214 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2020 Category: Universities & Medical Training Authors: Turoń-Skrzypińska A, Pawlukowska W, Szylińska A, Tomska N, Mikołajczyk-Kocięcka A, Ptak M, Dutkiewicz G, Rotter I Tags: Medicina (Kaunas) Source Type: research

BRCA1 and BRCA2 Gene Mutations and Lung Cancer Sisk: A Meta-Analysis.
Conclusion: With the limitation of the retrospective study design and severe heterogeneity, these results inform clinicians and relevant families that BRCA1 and BRCA2 mutation carriers have no increased risk of lung cancer. PMID: 32349445 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2020 Category: Universities & Medical Training Authors: Lee YC, Lee YC, Li CY, Lee YL, Chen BL Tags: Medicina (Kaunas) Source Type: research