Sex Differences in Insomnia and Circadian Rhythm Disorders: A Systematic Review
Medicina (Kaunas). 2024 Mar 13;60(3):474. doi: 10.3390/medicina60030474.ABSTRACTInsomnia and circadian rhythm disorders are increasingly common in modern society and lead to significant challenges for people's health and well-being. Some studies suggests that men and women differ in neurohormonal secretion, biological processes, and brain morphology. Thus, such differences may affect the etiology, manifestation, and course of sleep disorders, including insomnia and circadian rhythm. This systematic review aims to synthesize the existing literature on sex differences in insomnia and circadian rhythm disorders. PubMed, MEDLI...
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Evelina Paj ėdienė Vilt ė Urbonavičiūtė Vita Ramanauskait ė Lukas Strazdauskas Ambra Stefani Source Type: research

Environmental Exposure to Pesticides and the Risk of Child Neurodevelopmental Disorders
Conclusions: The areas with the highest greenhouse concentration had higher incidences of neurodevelopmental disorders, particularly in boys, and lower age of referral. Chromosomal abnormalities were prevalent for prenatal diagnoses, gestational age below thirty-two weeks for perinatal diagnoses, and brain damage for postnatal diagnoses. Future studies should analyze the connection between pesticide exposure and neurodevelopmental disorders using spatial point pattern analysis.PMID:38541201 | PMC:PMC10972353 | DOI:10.3390/medicina60030475 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Rocio Parr ón-Carrillo Bruno Jos é Nievas-Soriano Tesif ón Parrón-Carreño David Lozano-Paniagua Rub én Trigueros Source Type: research

The Role of Continuous Glucose Monitoring in Detecting Early Dysglycemia and Clinical Outcomes in Patients with Cystic Fibrosis
Medicina (Kaunas). 2024 Mar 14;60(3):477. doi: 10.3390/medicina60030477.ABSTRACTCystic fibrosis-related diabetes (CFRD) is the most common comorbidity in patients with cystic fibrosis (CF). CFRD has been correlated with important clinical outcomes, including poor nutrition, reduced pulmonary function, and earlier mortality. However, clinical decline due to abnormalities of blood glucose (dysglycemia) begins early in CF, before the diagnosis of CFRD by the gold-standard oral glucose tolerance test (OGTT). Continuous glucose monitoring (CGM) has been validated in patients with CF and has been recognized as a valuable tool in...
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Lora Stanka Kirigin Bilo š Velimir Altabas Andrea Vuki ć Dugac Maja Bareti ć Source Type: research

Primary Thyroid Lymphoma: A Retrospective-Observational Study in a Single Institutional Center
Conclusions: PTL represents a diagnosis that needs to be taken into account, especially in women with a history of Hashimoto autoimmune thyroiditis, presenting a cervical tumor with progressive growth. PTL is a lymphoid neoplasia with favorable outcome, with relatively long survival if it is diagnosed at younger ages.PMID:38541203 | PMC:PMC10971821 | DOI:10.3390/medicina60030476 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Octavia Vita Alis Dema Robert Barna Remus Cornea Dan Brebu Mihaela Vlad Oana Popa Ioana Muntean Diana Szilagyi Mihaela Iacob Maria Iordache Marioara Cornianu Dorela Codruta Lazureanu Source Type: research

Relationship between < em > XPA < /em > , < em > XPB/ERCC3 < /em > , < em > XPF/ERCC4 < /em > , and < em > XPG/ERCC5 < /em > Polymorphisms and the Susceptibility to Head and Neck Carcinoma: A Systematic Review, Meta-Analysis, and Trial Sequential Analysis
Conclusions: The analysis identified two polymorphisms, rs17655 and rs751402, as being significantly associated with the risk of HNC. The study underscored the influence of various factors, such as the type of cancer, ethnicity, source of control, and sample size on these associations.PMID:38541204 | PMC:PMC10972270 | DOI:10.3390/medicina60030478 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Mohammad Moslem Imani Masoumeh Basamtabar Sattar Akbari Edris Sadeghi Masoud Sadeghi Source Type: research

Exposure to Environmental Pesticides and the Risk of Autism Spectrum Disorders: A Population-Based Case-Control Study
Conclusions: Overall, this research suggests a connection between heightened environmental pesticide exposure due to increased agricultural use and autism.PMID:38541205 | PMC:PMC10972278 | DOI:10.3390/medicina60030479 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Pablo Rom án Cristofer Ruiz-Gonz ález Lola Rueda-Ruzafa Diana Cardona Mar Requena Raquel Alarc ón Source Type: research

Exercise May Increase Oxidative Stress in the Sciatic Nerve in Streptozotocin-Induced Diabetic Rats
Conclusions: Exercise may prevent DPN in rats with DM, possibly through nonantioxidant mechanisms.PMID:38541206 | PMC:PMC10972209 | DOI:10.3390/medicina60030480 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Koji Nonaka Junichi Akiyama Satsuki Une Source Type: research

Assessing the Effect of Enzymatic Debridement on the Scar Quality in Partial-Thickness Burns to Deep Dermal Burns of the Hand: A Long-Term Evaluation
Conclusions: In summary, it can be concluded that the objective skin quality following enzymatic debridement is comparable to that of healthy skin after 12 months and subjectively fares better than that after tangential excision. This confirms the superiority of enzymatic debridement in the treatment of deep dermal burns of the hand and solidifies its position as the gold standard.PMID:38541207 | PMC:PMC10972138 | DOI:10.3390/medicina60030481 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Wolfram Heitzmann Alexandra Schulz Paul Christian Fuchs Jennifer Lynn Schiefer Source Type: research

PD-L1 Expression and Tumour Microenvironment Patterns in Resected Non-Small-Cell Lung Cancer
Conclusions: This study results revealed that rates of PD-L1 expression correlated among three scoring methods (TPS, IC, and CPS). Moreover, PD-L1 expression was significantly associated with smoking intensity, squamous histology, and tumour-infiltrating immune cells.PMID:38541208 | PMC:PMC10972066 | DOI:10.3390/medicina60030482 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Giedr ė Gurevičienė Jurgita Matulion ė Lina Po škienė Skaidrius Miliauskas Marius Žemaitis Source Type: research

Evaluating the Clinical Utility of Brachial Plexus Block for Reducing Opioid Exposure in Pediatric Elbow Fracture Surgery: A Retrospective Cohort Study
Conclusions: SCB application in pediatric patients who underwent elbow fracture surgery significantly reduced opioid exposure and had a high success rate when performed using ultrasound guidance by an expert. Furthermore, the complication risk and surgical delay were minimal.PMID:38541209 | PMC:PMC10971820 | DOI:10.3390/medicina60030483 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Kunhyung Bae Yeon Ju Kim Hyo Won Lim Michael Seougcheol Kang Ha-Jung Kim Won Uk Koh Young-Jin Ro Jooyeon Cho Hwa Jung Kim Soo-Sung Park Yoon Hae Kwak Hyungtae Kim Source Type: research

Arthroscopic Medialization Partial Repair with Biologic Interposition Tuberoplasty for Large to Massive Irreparable Rotator Cuff Tear
Medicina (Kaunas). 2024 Mar 14;60(3):484. doi: 10.3390/medicina60030484.ABSTRACTAn irreparable rotator cuff tear is a challenging condition to treat, and various treatment modalities are being introduced. Medialization in the partial repair method has the limitation of exposing the tuberosity, while tension-free biologic interposition tuberoplasty using acellular dermal matrix has the limitation of exposing the humeral head. The authors believe that by combining these two techniques, it is possible to complement each other's limitations. Therefore, they propose a surgical method that combines medialization and biologic int...
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Jae-Wook Jung Joong-Bae Seo Jun-Yeul Lee Jae-Sung Yoo Source Type: research

The Association between Red Blood Cell Distribution Width and Mortality Risk after Hip Fracture: A Meta-Analysis
Conclusions: Greater RDW values at admission or before surgery were associated with a higher risk of short-term and long-term mortality following hip fractures. Because RDW can be easily measured using a routine blood test at a low cost, this parameter is promising as an indicator of mortality in elderly patients with hip fractures.PMID:38541211 | PMC:PMC10972257 | DOI:10.3390/medicina60030485 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Bao Tu Thai Nguyen Duy Nguyen Anh Tran Tan Thanh Nguyen Yi-Jie Kuo Yu-Pin Chen Source Type: research

MicroRNA Expression in Endometrial Cancer: Current Knowledge and Therapeutic Implications
Conclusions: Although their epigenetic regulation remains unknown, these upregulated molecules derived from EVs are feasible markers for the early detection of endometrial cancer. The modulation of these miRNA molecules should be assessed during different treatments or if recurrence develops in response to a targeted treatment modality.PMID:38541212 | PMC:PMC10972089 | DOI:10.3390/medicina60030486 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Irene Iavarone Rossella Molitierno Pietro Fumiento Maria Giovanna Vastarella Stefania Napolitano Maria Teresa Vietri Pasquale De Franciscis Carlo Ronsini Source Type: research

Dilatation and Curettage after Uterine Artery Embolization versus Methotrexate Injection for the Treatment of Cesarean Scar Pregnancy: A Single-Center Experience
Conclusions: In our experience, administration of MTX is not recommended as the primary treatment or pre-treatment. Dilatation and curettage after uterine artery embolization are better than methotrexate injection for the treatment of cesarean scar pregnancy in a single-institution series in terms of complete recovery and length of hospital stay.PMID:38541213 | PMC:PMC10971887 | DOI:10.3390/medicina60030487 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Basilio Pecorino Giuseppe Scibilia Bianca Mignosa Maria Cristina Teodoro Benito Chiofalo Paolo Scollo Source Type: research

Social Inhibition and Depressive Symptoms among Couples with Children with Autism Spectrum Disorder: The Mediating Role of Perceived Family Support
Conclusions: In line with related studies, social inhibition was associated with depressive symptoms. At the same time, perceived family support could be a mediator of depression. Gender differences in emotional expression, influenced by cultural norms and distinct role expectations within the family context, may elucidate why only wives' perceived family support could impact husbands' depressive symptoms. These results underscore the potential importance of interventions aimed at addressing social inhibition and enhancing perceived family support to alleviate depressive symptoms in this population. Additionally, encouragi...
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Ting Pan Tinakon Wongpakaran Nahathai Wongpakaran Bijing He Danny Wedding Source Type: research