Fusobacterium nucleatum carcinogenesis and drug delivery interventions

This article presents a comprehensive review of microbial communities especially F. nucleatum in tumor tissue, exploring their roles and underlying mechanisms in tumor development, treatment, and prevention. When the tumor-associated F. nucleatum is killed, the host immune response is activated to recognize tumor cells. Bacteria epitopes restricted by the host antigens, can be identified for future anti-bacteria/tumor vaccine development.PMID:38643839 | DOI:10.1016/j.addr.2024.115319
Source: Advanced Drug Delivery Reviews - Category: Drugs & Pharmacology Authors: Source Type: research