Potential new therapy takes aim at a lethal esophageal cancer's glutamine addiction
(Medical University of South Carolina) Medical University of South Carolina investigators have exploited a metabolic quirk of certain cancers known as glutamine addiction to identify a potential new therapy for esophageal cancer. After characterizing the pathway involved in cancer progression, they tested a new combination treatment in both cells and animal models, with promising results. The next step is to secure funding to bring the new combination regimen to clinical trial. Their findings are reported in Nature Communications. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 20, 2019 Category: International Medicine & Public Health Source Type: news

Cancer Research UK: Less chemotherapy better for older patients with some advanced cancers
(Cancer Research UK) Less chemotherapy is as effective at controlling disease for elderly or frail patients with advanced cancer of the stomach or oesophagus (food pipe), and leads to fewer side effects such as diarrhoea and lethargy. These are the results of a Cancer Research UK funded study, presented prior to the ASCO conference today (Wednesday). (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - May 15, 2019 Category: International Medicine & Public Health Source Type: news

New Radiotherapy Can Double Two-Year Survival for Mesothelioma
A novel radiotherapy regimen can double the chances of surviving two or more years with pleural mesothelioma, according to Dr. Marco Trovo at University Hospital of Udine in Italy. Trovo is the lead author of a study involving 108 patients treated for malignant mesothelioma between 2014 and 2018 at the National Cancer Institute in Aviano, Italy. He presented the findings this week at the annual European Society for Therapeutic Radiology and Oncology convention in Milan. “Radiotherapy has evolved dramatically in the last few years, so we wanted to see if it could now be used to prevent cancer from spreading to nearby ...
Source: Asbestos and Mesothelioma News - May 14, 2019 Category: Environmental Health Authors: Matt Mauney Source Type: news

EPA Ignored Advice from Staff Experts When Issuing New Asbestos Rule
More than a dozen senior officials and experts at the Environmental Protection Agency urged the EPA to ban asbestos outright, a new report shows. Two internal memos obtained by the Asbestos Disease Awareness Organization and shared with the New York Times reveal the EPA’s own scientists and lawyers advised the agency to issue a complete ban of asbestos instead of the recent regulations that only restricted its domestic use. In the memos, dated Aug. 10, 2018, EPA staff members wrote that the agency “should seek to ban all new uses of asbestos because the extreme harm from this chemical substance outweighs any ...
Source: Asbestos and Mesothelioma News - May 8, 2019 Category: Environmental Health Authors: Matt Mauney Source Type: news

New model improves staging and risk predictions for esophageal cancer patients
(American Association for Thoracic Surgery) A new nomogram for assessing metastatic risk in esophageal cancer patients shows promise for more accurate risk-stratification, which is particularly relevant for stage T2 patients. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 6, 2019 Category: Cancer & Oncology Source Type: news

Mauritian medical herbs possess antitumor properties
(Far Eastern Federal University) Far Eastern Federal University (FEFU) scientists teamed up with colleagues from the UK and Mauritius and experimentally demonstrated that extracts of the endemic (i.e. growing only on this island) medicinal herb leaves Acalypha integrifolia, Eugenia tinifolia, and Labourdonnaisia glauca stop the proliferation of esophageal squamous carcinoma cells, ones of the most deadly cancer type worldwide. A related article is published in the Acta Naturae journal. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 22, 2019 Category: Cancer & Oncology Source Type: news

New UCLA center focusing on disorders of the esophagus to be named for Robert G. Kardashian
TheDavid Geffen School of Medicine at UCLA has established a center for holistic, patient-centered treatment, research and education related to disorders of the esophagus.The new center is named in memory of Robert G. Kardashian, a prominent Los Angeles attorney who died of esophageal cancer in 2003. Kardashian ’s family will launch fundraising efforts to provide resources for the center’s key initiatives and activities.TheRobert G. Kardashian Center for Esophageal Health, which is based in the UCLA Vatche and Tamar Manoukian Division of Digestive Diseases, combines UCLA Health ’s collective expertise in ...
Source: UCLA Newsroom: Health Sciences - April 18, 2019 Category: Universities & Medical Training Source Type: news

New UCLA center focusing on disorders of the esophagus to be named for Robert Kardashian
TheDavid Geffen School of Medicine at UCLA has established a center for holistic, patient-centered treatment, research and education related to disorders of the esophagus.The new center is named in memory of Robert G. Kardashian, a prominent Los Angeles attorney who died of esophageal cancer in 2003. Kardashian ’s family will launch fundraising efforts to provide resources for the center’s key initiatives and activities.TheRobert G. Kardashian Center for Esophageal Health, which is based in the UCLA Vatche and Tamar Manoukian Division of Digestive Diseases, combines UCLA Health ’s collective expertise in ...
Source: UCLA Newsroom: Health Sciences - April 17, 2019 Category: Universities & Medical Training Source Type: news

City of Hope scientists are using combination immunotherapy to treat advanced cancers
(City of Hope) City of Hope physician-scientists recently opened two clinical trials to investigate a combination of cytokines and immunotherapy that may be able to transform nearly-impossible-to-treat cancer into a disease that can be corralled into remission. Daneng Li, M.D., is treating patients with advanced liver (hepatocellular) cancer, while Joseph Chao, M.D., is treating patients with advanced stomach and esophageal cancer (gastric and gastroesophageal junction adenocarcinoma). (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 8, 2019 Category: Cancer & Oncology Source Type: news

Combo of virotherapy and radiotherapy shows early promise in patients with esophageal cancer
(American Association for Cancer Research) The experimental oncolytic adenovirus telomelysin (OBP-301) in combination with radiotherapy was safe and showed early clinical efficacy in vulnerable patients with esophageal cancer, according to results from a phase I clinical trial presented at the AACR Annual Meeting 2019, March 29-April 3. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 2, 2019 Category: Cancer & Oncology Source Type: news

Drinking scalding-hot tea may increase esophagus cancer risk
(Reuters Health) - Tea drinkers who love a scalding-hot cup of the beverage may want to let it cool down a bit to avoid an increased risk of esophagus cancer, a new study suggests. (Source: Reuters: Health)
Source: Reuters: Health - March 29, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

Medical News Today: Hot tea may raise esophageal cancer risk
A new, large prospective study suggests that people who regularly drink very hot tea may raise their risk of developing esophageal cancer. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 22, 2019 Category: Consumer Health News Tags: Head and Neck Cancer Source Type: news

Can Drinking Very Hot Tea Raise Your Risk Of Esophageal Cancer?
A study showed that drinking tea above this temperature was associated with higher esophageal cancer rates. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - March 21, 2019 Category: Pharmaceuticals Authors: Bruce Y. Lee, Contributor Source Type: news

Drinking hot tea and the risk of esophageal cancer
New research suggests you may want to avoid drinking your tea scalding hot (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - March 21, 2019 Category: Consumer Health News Source Type: news

Hot Tea May Boost Esophageal Cancer Risk
Title: Hot Tea May Boost Esophageal Cancer RiskCategory: Health NewsCreated: 3/21/2019 12:00:00 AMLast Editorial Review: 3/21/2019 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - March 21, 2019 Category: Cancer & Oncology Source Type: news

Scalding Hot Tea May Boost Esophageal Cancer Risk
A previous study linked hot tea with esophageal cancer, but this new one is the first to pinpoint a specific temperature, according to the researchers. (Source: WebMD Health)
Source: WebMD Health - March 20, 2019 Category: Consumer Health News Source Type: news

Hot tea linked to increased risk of esophageal cancer
People who like hot tea may want to wait until it gets cooler before taking that first sip. (Source: Health News - UPI.com)
Source: Health News - UPI.com - March 20, 2019 Category: Consumer Health News Source Type: news

Drinking Very Hot Tea Almost Doubles Risk Of Cancer, New Study Says
This study, published Wednesday in the International Journal of Cancer, was the first to pinpoint a specific temperature, according to the authors. Esophageal cancer is the eighth most common cancer in the world and is often fatal, killing approximately 400,000 people every year, according to the International Agency for Research on Cancer. It is usually caused by repeated injury to the esophagus due to smoke, alcohol, acid reflux and — maybe — hot liquids. The esophagus is a long tube through which swallowed food and liquids travel to reach the stomach. The American Cancer Society estimates that 13,750 new cas...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - March 20, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News tea Source Type: news

Drinking very hot tea almost doubles risk of cancer, new study says
Many people start their day with a cup of tea. But those who drink it piping hot could be increasing their risk of esophageal cancer, according to a new study. (Source: CNN.com - Health)
Source: CNN.com - Health - March 20, 2019 Category: Consumer Health News Source Type: news

Drinking hot tea or coffee could more than DOUBLE the risk of developing cancer of the oesophagus
The study looked at the drinking habits of 50,045 people who lived in north-eastern Iran. People in the UK and US typically drink beverages below 60°C. (Source: the Mail online | Health)
Source: the Mail online | Health - March 20, 2019 Category: Consumer Health News Source Type: news

Drinking hot tea linked with elevated risk of esophageal cancer
(Wiley) Previous studies have revealed a link between hot tea drinking and risk of esophageal cancer, but until now, no study has examined this association using prospectively and objectively measured tea drinking temperature. A new International Journal of Cancer study achieved this by following 50,045 individuals aged 40 to 75 years for a median of 10 years. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 20, 2019 Category: International Medicine & Public Health Source Type: news

Adenocarcinoma, High - Grade Dysplasia Up With Barrett Esophagus
But Barrett esophagus length has decreased, as has prevalence of low - grade dysplasia on endoscopy (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - March 18, 2019 Category: Cancer & Oncology Tags: Gastroenterology, Oncology, Pathology, Journal, Source Type: news

Adenocarcinoma, High-Grade Dysplasia Up With Barrett Esophagus
MONDAY, March 18, 2019 -- The prevalence of high-grade dysplasia (HGD) and esophageal adenocarcinoma (EAC) has significantly increased since 1995 in patients with Barrett esophagus (BE), according to a study published in the February issue of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 18, 2019 Category: Pharmaceuticals Source Type: news

44-Gene Assay Predicts Response, Survival in Esophageal Cancer (CME/CE)
(MedPage Today) -- DNA-damaging immune response in tumors correlates with neoadjuvant therapy efficacy, will aid personalized treatment (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - March 15, 2019 Category: Gastroenterology Source Type: news

Current Treatment of Esophageal Cancer and Promising Clinical Trials Underway
Dr. Ku discusses considerations in the treatment of esophageal cancer, current treatments, and the emerging role of immunotherapy. (Source: CancerNetwork)
Source: CancerNetwork - March 13, 2019 Category: Cancer & Oncology Authors: Geoffrey Y. Ku, MD Source Type: news

Assay Predicts Response, Survival in Esophageal Cancer
(MedPage Today) -- Tumor positivity to DNA-damaging neoadjuvant therapy could hone patient treatment (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - March 12, 2019 Category: Gastroenterology Source Type: news

Newly identified drug targets could open door for esophageal cancer therapeutics
(Case Western Reserve University) Blocking two molecular pathways that send signals inside cancer cells could stave off esophageal adenocarcinoma (EAC), the most common esophageal malignancy in the United States, according to new research out of Case Western Reserve University School of Medicine. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 27, 2019 Category: Cancer & Oncology Source Type: news

Video: Esophagectomy
Esophagectomy is surgery to remove your esophagus. It's used to treat Barrett's esophagus and esophageal cancer. (Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - February 27, 2019 Category: Consumer Health News Source Type: news

Targeting Certain Lymph Nodes Could Change Mesothelioma Treatment
Thoracic surgeon Dr. Joseph Friedberg at the University of Maryland School of Medicine has identified previously underutilized lymph nodes that could change the way pleural mesothelioma is diagnosed, staged and treated. Friedberg is the head of the Division of Thoracic surgery at Maryland and director of the Mesothelioma and Thoracic Oncology Treatment and Research Center. The findings are based upon the posterior intercostal lymph nodes — a part of the lymphatic system between the ribs near the spine — in 56 mesothelioma patients who were part of a recent clinical trial. Friedberg detailed the groundbreaking f...
Source: Asbestos and Mesothelioma News - February 26, 2019 Category: Environmental Health Authors: Matt Mauney Source Type: news

Results of early endoscopic exam critical for assessment of Barrett's patients
(American Society for Gastrointestinal Endoscopy) A new study indicates that both high-grade abnormal cellular changes (dysplasia) and esophageal adenocarcinoma (a form of cancer) have increased in the last 25 years among people with a digestive condition known as Barrett's esophagus. The study report, Increasing prevalence of high-grade dysplasia and adenocarcinoma on index endoscopy in Barrett's esophagus over the past 2 decades, is published in the February issue of GIE: Gastrointestinal Endoscopy, the peer-reviewed journal of the American Society for Gastrointestinal Endoscopy (ASGE). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 14, 2019 Category: International Medicine & Public Health Source Type: news

Why lemons are a cheap but effective way to maintain good oral hygiene
(Natural News) Maintaining good oral hygiene does not need expensive mouthwash or toothpaste. Instead, use lemons. Lemons and other citrus fruits have been associated with many health benefits, such as a lowered risk for gastrointestinal and esophageal cancer, and cardiovascular diseases. In a recent study, it was also revealed that the extract of the rind... (Source: NaturalNews.com)
Source: NaturalNews.com - February 12, 2019 Category: Consumer Health News Source Type: news

Father of two dies from cancer after doctors missed throat tumour
Ryan Greenan, from Wester Hailes in Edinburgh, was just 35 when he died last month because of oesophageal cancer which spread to his lungs and liver before he was finally diagnosed. (Source: the Mail online | Health)
Source: the Mail online | Health - February 5, 2019 Category: Consumer Health News Source Type: news

Father of two dies from cancer after doctors missed brain tumour
Ryan Greenan, from Wester Hailes in Edinburgh, was just 35 when he died last month because of oesophageal cancer which spread to his lungs and liver before he was finally diagnosed. (Source: the Mail online | Health)
Source: the Mail online | Health - February 4, 2019 Category: Consumer Health News Source Type: news

Mapping oesophageal cancer genes leads to new drug targets
(Cancer Research UK) Mutations that cause oesophageal adenocarcinoma (OAC) have been mapped in unprecedented detail -- unveiling that more than half could be targeted by drugs currently in trials for other cancer types. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - February 4, 2019 Category: Biology Source Type: news

Medical News Today: What is a benign esophageal stricture?
A benign esophageal stricture is a gradual narrowing of the esophagus that has no medical links to cancer. Learn more about the condition here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 1, 2019 Category: Consumer Health News Tags: Ear, Nose and Throat Source Type: news

New Device Finds Patients at Risk for Esophageal Cancer New Device Finds Patients at Risk for Esophageal Cancer
A novel esophageal sampling device identifies patients at risk for esophageal cancer without standard endoscopy.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 29, 2019 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Cancer warning - do you have this feeling in your throat while eating? Hidden tumour signs
CANCER symptoms vary depending on which part o the body is affected by a tumour. You could be at risk of deadly tumour signs if you have this feeling in your throat while swallowing your food. Symptoms of oesophageal cancer revealed. (Source: Daily Express - Health)
Source: Daily Express - Health - January 24, 2019 Category: Consumer Health News Source Type: news

Endoscopic Resection Brings Excitement to Esophageal Cancer Treatment
Cancer Network spoke with Dr. Daniela Molena about the advancements in the treatment of esophageal cancer, including the safety and importance of endoscopic resection for the disease. (Source: CancerNetwork)
Source: CancerNetwork - January 23, 2019 Category: Cancer & Oncology Authors: Daniela Molena, MD Source Type: news

Test for esophageal cancer could save millions of lives
(Johns Hopkins Medicine) Cancer of the esophagus claims more than 400,000 lives around the world each year. With no efficient, reliable method of screening for the disease, by the time symptoms become apparent, it's often too late to save the patient. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 22, 2019 Category: International Medicine & Public Health Source Type: news

Adjuvant Durvalumab Beneficial in Esophageal/GEJ Cancer?
Cancer Network spoke with Dr. Hirva Mamdani about the role and efficacy of adjuvant durvalumab in patients with Esophageal/GEJ Cancer. (Source: CancerNetwork)
Source: CancerNetwork - January 22, 2019 Category: Cancer & Oncology Authors: Hirva Mamdani, MD Source Type: news

New Standard of Care in PD-L1+ Esophageal Cancer? New Standard of Care in PD-L1+ Esophageal Cancer?
Patients with advanced esophageal cancer who have a high level of PD-L1 showed improved survival on poembrolizumab compared to standard chemotherapy.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 21, 2019 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Keytruda Extends OS in Advanced Esophageal Cancer
(MedPage Today) -- Improvement over chemo seen in second-line for PD-L1 expressing tumors (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - January 18, 2019 Category: Gastroenterology Source Type: news

Pembrolizumab Extends OS in Advanced Esophageal Cancer
(MedPage Today) -- Improvement over chemo seen in second-line for PD-L1 expressing tumors (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - January 18, 2019 Category: Gastroenterology Source Type: news

A New Standard of Care for Some Advanced Esophageal Cancer Patients
Pembrolizumab showed promise in the second-line setting for patients with metastatic esophageal cancer and high PD-L1 expression. (Source: CancerNetwork)
Source: CancerNetwork - January 18, 2019 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Mapping residual esophageal tumors -- a glimpse into the future?
(Osaka University) Esophageal cancer is the sixth most common cause of cancer-associated death and continues to have a very poor prognosis. Although tissue samples from esophageal cancer patients are examined after treatment, current methods do not provide a reliable picture of treatment outcome. Researchers at Osaka University developed a typing system based on residual tumor patterns to predict long-term treatment outcomes and design individual treatment protocols for esophageal cancer patients. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 10, 2019 Category: Cancer & Oncology Source Type: news

Less Invasive Surgery Wins in Esophageal Cancer
(MedPage Today) -- Large reduction in major complications at 1 month out (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - January 9, 2019 Category: Gastroenterology Source Type: news

Fewer Complications Found With Hybrid Surgery for Esophageal Cancer
WEDNESDAY, Jan. 9, 2019 -- Hybrid minimally invasive esophagectomy results in lower incidence of intraoperative and postoperative major complications compared with open esophagectomy for esophageal cancer, according to a study published in the Jan.... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 9, 2019 Category: Pharmaceuticals Source Type: news

Breath Test To Detect Multiple Cancers Early Begins Large Trial
(CNN) — A breathalyzer designed to detect multiple cancers early is being tested in the UK. Several illnesses are known to create signature smells from the body, including typhoid fever reported to smell like baked bread and the aroma of acetone, said to be similar to rotten apples, on the breath of diabetics. Recent research has also shown that a person’s breath could also indicate the presence of cancer. To test this theory, Cancer Research UK have launched a two-year trial into a clinical device, called the Breath Biopsy, to find out if exhaled airborne molecules can be useful for cancer detection. (Image cr...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 3, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Cancer CNN Local TV Source Type: news