Clinical Trial Will Test if Vaccine Can Prevent, Delay Cancer Recurrence
Researchers hope the vaccine they soon will begin testing in humans will prevent or delay the recurrence of some cancers. Patients with pleural mesothelioma will be among the first to receive the H1299 lysate vaccine with an Iscomatrix adjuvant. The vaccine is a form of immunotherapy designed to trigger the body's immune system into preventing new cancer growth. The National Institutes of Health(NIH) will begin conducting the three-year trial in September. It’s designed for patients whom recently completed standard treatments, including surgery, chemotherapy or radiation, and whom have little or no residual disease a...
Source: Asbestos and Mesothelioma News - August 20, 2014 Category: Environmental Health Authors: Tim Povtak Tags: Research & Clinical Trials Source Type: news

Biomarker Panel Could Improve Detection of Esophageal CancerBiomarker Panel Could Improve Detection of Esophageal Cancer
A new 4-protein biomarker panel could improve detection of esophageal cancer, and might help guide treatment. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - August 14, 2014 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Is UK obesity fuelling an increase in 10 cancers?
Conclusion This large UK cohort study of more than 5 million people has found that, although there was variation in the effect of BMI on different cancers, a higher BMI was associated with increased risk of several cancers. Overall, the researchers estimated that a 1kg/m² population-wide increase in BMI would result in 3,790 additional people in the UK each year developing uterus, gallbladder, kidney, cervix, thyroid, leukaemia, liver, colon, ovarian or postmenopausal breast cancer. However, not all of the identified links were completely clear, with some showing a clearer linear association between increasing BMI an...
Source: NHS News Feed - August 14, 2014 Category: Consumer Health News Tags: Obesity Cancer Source Type: news

Daily aspirin 'reduces cancer risk', study finds
Conclusion While the findings on aspirin and cancer show promise, it is not clear that the results are reliable from the methods reportedly used to compile this review. This is because it included studies of varying design and quality, with much of the evidence coming from observational studies, which, while useful, cannot be totally relied on to test the effectiveness of healthcare interventions. It's not clear how the studies included in the review were chosen and whether others on the same topic were excluded. It is also not clear whether or not this was a systematic review, where studies are rigorously appraised for ...
Source: NHS News Feed - August 6, 2014 Category: Consumer Health News Tags: Cancer Medication Source Type: news

Daily aspirin 'cuts cancer deaths'
An analysis suggests taking a small dose of aspirin every day can prevent deaths from bowel, stomach and oesophageal cancers. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - August 6, 2014 Category: Consumer Health News Source Type: news

Scientific review finds aspirin significantly cuts cancer rates
LONDON (Reuters) - Taking a small daily dose of aspirin can significantly reduce the risk of developing - or dying from - bowel, stomach and oesophageal cancer, according to a large review of scientific studies. (Source: Reuters: Health)
Source: Reuters: Health - August 6, 2014 Category: Consumer Health News Tags: healthNews Source Type: news

Aspirin: Scientists believe cancer prevention benefits outweigh harms
(Queen Mary, University of London) New research from Queen Mary University of London reveals taking aspirin can significantly reduce the risk of developing -- and dying from -- the major cancers of the digestive tract, i.e. bowel, stomach and esophageal cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 5, 2014 Category: Cancer & Oncology Source Type: news

Well: Statins Tied to Lower Risk of Barrett’s Esophagus
Cholesterol-lowering statin drugs are associated with a lower risk of Barrett’s esophagus, a precancerous condition that can sometimes lead to esophageal cancer, a new study has found. (Source: NYT Health)
Source: NYT Health - July 28, 2014 Category: Consumer Health News Authors: By NICHOLAS BAKALAR Tags: Esophageal Cancer Body medicine and health Statins (Cholesterol-Lowering Drugs) Featured Source Type: news

Well: Statins Tied to Lower Risk of Barrett’s Esophagus
Cholesterol-lowering statin drugs are associated with a lower risk of Barrett’s esophagus, a precancerous condition that can sometimes lead to esophageal cancer, a new study has found. (Source: NYT)
Source: NYT - July 28, 2014 Category: Nutrition Authors: By NICHOLAS BAKALAR Tags: Esophageal Cancer Body medicine and health Statins (Cholesterol-Lowering Drugs) Featured Source Type: news

Study helps compare risks of treatments for early esophageal cancer
(Northwestern Memorial Hospital) A new study, published in the July 2014 issue of the Journal of the National Cancer Institute by Northwestern Medicine researchers, sheds new light on the risks associated with the growing popularity of endoscopic resection in the treatment of localized, early-stage esophageal cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 28, 2014 Category: Cancer & Oncology Source Type: news

Ganymed closes patient enrolment in Phase II FAST trial for gastroesophageal cancer
Germany-based Ganymed Pharmaceuticals has completed patient enrolment in its Phase II first-line treatment of patients with CLDN18.2-positive advanced adenocarcinomas of the stomach, the esophagus or the gastroesophageal junction (FAST) clinical tria… (Source: Drug Development Technology)
Source: Drug Development Technology - July 24, 2014 Category: Pharmaceuticals Source Type: news

CNIO scientists discover that pluripotency factor NANOG is also active in adult organisms
(Centro Nacional de Investigaciones Oncologicas (CNIO)) Scientists from the Spanish National Cancer Research Center (CNIO) have discovered that NANOG, an essential gene for embryonic stem cells, also regulates cell division in stratified epithelia in adult organisms. According to the conclusions of the study, published in the journal Nature Communications, this factor could also play a role in the formation of tumors derived from stratified epithelia of the esophagus and skin. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 9, 2014 Category: Global & Universal Source Type: news

'Surgery Remains Cornerstone' for Early Esophageal Cancer'Surgery Remains Cornerstone' for Early Esophageal Cancer
Negative results from a phase 3 trial of early-stage esophageal cancer call into question the role of preoperative chemoradiation, although previous trials have shown a benefit. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 3, 2014 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

ESMO: Erbitux No Help in Esophageal Ca (CME/CE)
(MedPage Today) -- Survival in esophageal cancer did not improve with the addition of cetuximab (Erbitux) to conventional chemoradiation, results of a randomized trial showed. The study was among several notable reports from the European Society for Medical Oncology World Congress on Gastrointestinal Cancer. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - July 2, 2014 Category: Primary Care Source Type: news

Mucositis – Prevention and Treatments for...
Chemotherapy-induced mucositis is the inflammation of your mucous membranes, which are tissues that line your digestive system – all the way from your mouth, esophagus, stomach, intestines, rectum to your anus. (Source: About.com Breast Cancer)
Source: About.com Breast Cancer - June 26, 2014 Category: Cancer & Oncology Authors: breastcancer.guide at about.com Tags: health Source Type: news

Highlights from the June issue of GIE: Gastrointestinal Endoscopy
(American Society for Gastrointestinal Endoscopy) The June issue of GIE: Gastrointestinal Endoscopy, the monthly peer-reviewed scientific journal of the American Society for Gastrointestinal Endoscopy, features a study reporting that the annual incidence rate of esophageal cancer among patients with Barrett's esophagus with low-grade dysplasia is 0.54 percent; a study showing that metabolic syndrome and smoking heighten concerns regarding colorectal cancer screening in men with these risk factors; and a new ASGE guideline on endoscopy in patients with lower gastrointestinal bleeding. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 23, 2014 Category: Global & Universal Source Type: news

PET/MRI holds its own for esophageal cancer staging
The benefits of PET/MRI may be expanding to esophageal cancer, according to (more) (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - June 2, 2014 Category: Radiology Source Type: news

Barrett Esophagus: Symptoms and Endoscopic FeaturesBarrett Esophagus: Symptoms and Endoscopic Features
Are all patients with Barrett esophagus at an increased risk for esophageal cancer? This new study looks at what symptoms and endoscopic features can tell the clinician. The American Journal of Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 15, 2014 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Autophagic activation with Nimotuzumab enhances chemo-radiosensitivity
(Society for Experimental Biology and Medicine) Nimotuzumab, a humanized IgG1 isotype monoclonal antibody targeting epidermal growth factor receptor (EGFR), enhanced the sensitivity of esophageal squamous cell carcinoma cells with high expression of EGFR to chemo-radiotherapy, due to autophagic activation mediated by this agent. It was concluded that autophagic activation mediated by nimotuzumab could promote autophagic cell death and produce additive antitumor effects. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 13, 2014 Category: Global & Universal Source Type: news

The 9 Types of Short- and Long-Term Side...
Radiation therapy is frequently used with or without chemotherapy and surgery for the treatment of lung cancer. Short-term side effects such as skin irritation, fatigue, and inflammation of the esophagus can occur. Long-term side effects including radiation pneumonitis, pulmonary fibrosis, and secondary cancers should be discussed with your radiation oncologist. (Source: About.com Lung Cancer)
Source: About.com Lung Cancer - May 13, 2014 Category: Cancer & Oncology Tags: health Source Type: news

Gene discovery sparks hope for new throat cancer treatment
A NEWLY discovered gene linked to oesophageal cancer holds the promise of new treatments for the notoriously difficult-to-fight disease (Source: Daily Express - Health)
Source: Daily Express - Health - May 9, 2014 Category: Consumer Health News Source Type: news

Researchers present findings on promising biomarker for esophageal cancer
(University Hospitals Case Medical Center) A new biomarker for esophageal cancer shows promise in improving screening for this deadly disease and its precursor, Barrett's esophagus. Amitabh Chak, M.D., of University Hospitals Case Medical Center's Seidman Cancer Center and Case Western Reserve University School of Medicine, presented findings today at Digestive Disease Week in Chicago in a research forum titled 'Aberrant Vimentin Methylation in Esophageal Brushings: A Biomarker for Detecting Barrett's Esophagus and Esophageal Adenocarcinoma.' (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 5, 2014 Category: Cancer & Oncology Source Type: news

PPIs in Barrett EsophagusPPIs in Barrett Esophagus
Is the long-term use of PPIs associated with an increased or decreased risk of adenocarcinoma or high-grade dysplasia in patients with Barrett esophagus? Alimentary Pharmacology & Therapeutics (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - May 2, 2014 Category: Gastroenterology Tags: Gastroenterology Journal Article Source Type: news

Smoking, Drinking Combo Raises Odds for Esophageal Cancer
Title: Smoking, Drinking Combo Raises Odds for Esophageal CancerCategory: Health NewsCreated: 4/25/2014 12:35:00 PMLast Editorial Review: 4/28/2014 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - April 28, 2014 Category: Cancer & Oncology Source Type: news

Smoking, Drinking Combo Raises Odds for Esophageal Cancer
Study found having both unhealthy habits doubled risk of malignancy compared to having just one (Source: Cancercompass News: Other Cancer)
Source: Cancercompass News: Other Cancer - April 26, 2014 Category: Cancer & Oncology Source Type: news

Smoking, Drinking Combo Raises Odds for Esophageal Cancer
Study found having both unhealthy habits doubled risk of malignancy compared to having just one (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - April 26, 2014 Category: Cancer & Oncology Authors: webmaster at doctorslounge.com Tags: Oncology, Preventive Medicine, News, Source Type: news

Smoking, Drinking Combo Raises Odds for Esophageal Cancer
Study found having both unhealthy habits doubled risk of malignancy compared to having just one Source: HealthDay Related MedlinePlus Pages: Alcohol, Esophageal Cancer, Smoking (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - April 25, 2014 Category: Consumer Health News Source Type: news

Combination of Alcohol and Tobacco Increases Risk of Esophageal Cancer
Source: American College of Gastroenterology Related MedlinePlus Page: Esophageal Cancer (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - April 25, 2014 Category: Consumer Health News Source Type: news

FDA approves Cyramza for stomach cancer
The U.S. Food and Drug Administration today approved Cyramza (ramucirumab) to treat patients with advanced stomach cancer or gastroesophageal junction adenocarcinoma, a form of cancer located in the region where the esophagus joins the stomach. (Source: Food and Drug Administration)
Source: Food and Drug Administration - April 21, 2014 Category: American Health Source Type: news

Malawi: Malawi Tops Oesophageal Cancer List in Africa
[Malawi News Agency]Blantyre -A General Surgeon at Queen Elizabeth Central Hospital (QECH), Dr Luwano Kalongolera has said it is a known fact that in Africa, Malawi stands the highest ranking country facing oesophageal cancer (also known as cancer of the oesophagus). (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - April 18, 2014 Category: African Health Source Type: news

Cerfolio Leads the Charge for Robotics in Thoracic Surgery
Just a few years ago, renowned thoracic surgeon Robert Cerfolio, M.D., was one of the biggest robotic surgery skeptics, discounting the notion that a computer-controlled system could perform a precise operation in the chest better than he could as absurd. He is now its biggest proponent — taking a 180-degree turn. Cerfolio, the chief of thoracic surgery for the University of Alabama at Birmingham Health Care System, has performed more robotic thoracic operations using the da Vinci Surgical System in the past four years than anyone in the world. Robotic surgery involves tiny instruments attached to a robot remotely...
Source: Asbestos and Mesothelioma News - April 15, 2014 Category: Environmental Health Authors: Tim Povtak Tags: Treatment & Doctors Source Type: news

Is frequent mouthwash use linked to oral cancer?
Conclusion This multicentre study conducted across nine European countries has many strengths, including its large sample size. Most importantly, it adjusted for smoking and alcohol consumption, which are well-established risk factors for these cancers and could otherwise influence the association between oral health and dental hygiene and these cancers. The researchers also adjusted for other potential risk factors, such as socioeconomic status and how much fruit and vegetables people ate. However, there are some potential limitations. Although the researchers have made every effort to adjust for these confounders, as th...
Source: NHS News Feed - April 4, 2014 Category: Consumer Health News Tags: Cancer Source Type: news

FOLFOX: More Convenient for Esophageal Cancer?FOLFOX: More Convenient for Esophageal Cancer?
Final results of a phase 2/3 trial that pitted FOLFOX against chemoradiotherapy with fluorouracil and cisplatin for inoperable esophageal cancer show that FOLFOX is a more convenient choice. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - April 2, 2014 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Scientists discover a number of novel genetic defects which cause oesophageal cancer
(National University of Singapore) A team of scientists from the Cancer Science Institute of Singapore at the National University of Singapore and National University Cancer Institute Singapore, and their collaborators from the Cedars-Sinai Medical Centre, UCLA School of Medicine, demonstrated that a number of novel genetic defects are able to induce oesophageal cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 31, 2014 Category: Cancer & Oncology Source Type: news

Can Dental Hygiene Have an Impact on Lung Cancer?
We are learning more and more about chronic inflammation, and how it may lead to the development of cancer. This can be seen directly in some cancers in which cancer develops from local inflammation. Examples include HPV leading to cervical cancer and chronic esophageal reflux leading to esophageal cancer. But inflammation in one region of the body may also lead to the development of cancer in another region of the body....Read Full Post (Source: About.com Lung Cancer)
Source: About.com Lung Cancer - March 31, 2014 Category: Cancer & Oncology Source Type: news

Covidien's Barrx ablation system stems progression of esophagus disease, study says
Covidien's Barrx RF ablation system bests watchful waiting in helping to curb the progression of Barrett's esophagus, a condition that can lead to esophageal cancer. CovidienNews Well, Clinical Trials, Ablation, Endoscopic / Arthroscopicread more (Source: Mass Device)
Source: Mass Device - March 26, 2014 Category: Medical Equipment Authors: Arezu Sarvestani Source Type: news

Treatment helps reduce risk of esophagus disorder progressing to cancer
Among patients with the condition known as Barrett esophagus, treatment of abnormal cells with radiofrequency ablation (use of heat applied through an endoscope to destroy cells) resulted in a reduced risk of this condition progressing to cancer, according to a study in JAMA. In the last 3 decades, the incidence of esophageal cancer has increased more rapidly that other cancers in the Western world. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 26, 2014 Category: Consumer Health News Tags: GastroIntestinal / Gastroenterology Source Type: news

Treatment May Prevent Esophagus Condition From Progressing to Cancer
Title: Treatment May Prevent Esophagus Condition From Progressing to CancerCategory: Health NewsCreated: 3/25/2014 4:36:00 PMLast Editorial Review: 3/26/2014 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - March 26, 2014 Category: Cancer & Oncology Source Type: news

Treatment May Prevent Esophagus Condition From Progressing to Cancer
In study of patients with Barrett's esophagus, those who received radio-frequency ablation fared better (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - March 26, 2014 Category: Cancer & Oncology Authors: webmaster at doctorslounge.com Tags: Oncology, Pharmacy, Research, News, Source Type: news

Treatment May Prevent Esophagus Condition from Progressing to Cancer
In study of patients with Barrett's esophagus, those who received radio-frequency ablation fared better Source: HealthDay Related MedlinePlus Pages: Cancer, Esophagus Disorders (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - March 25, 2014 Category: Consumer Health News Source Type: news

Treatment helps reduce risk of esophagus disorder progressing to cancer
(The JAMA Network Journals) Among patients with the condition known as Barrett's esophagus, treatment of abnormal cells with radiofrequency ablation (use of heat applied through an endoscope to destroy cells) resulted in a reduced risk of this condition progressing to cancer, according to a study in the March 26 issue of JAMA. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 25, 2014 Category: Cancer & Oncology Source Type: news

Treatment May Prevent Esophagus Condition From Progressing to Cancer
In study of patients with Barrett's esophagus, those who received radio-frequency ablation fared better (Source: Cancercompass News: Other Cancer)
Source: Cancercompass News: Other Cancer - March 25, 2014 Category: Cancer & Oncology Source Type: news

CT perfusion useful for evaluating small esophageal tumors
CT perfusion can be used to evaluate esophageal cancers with small tumor diameters (more) (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - March 19, 2014 Category: Radiology Source Type: news

Smoking 'increases risk of breast cancer in older women by almost a fifth'
Study published in British Journal of Cancer found women who used to smoke were still 7% more at risk of diseaseSmoking increases the risk of breast cancer in older women by almost a fifth, a study has found. The discovery adds to a growing weight of evidence linking exposure to tobacco smoke with the disease.US scientists who tracked the progress of around 186,000 women aged 50 to 71 found that those who smoked were 19% more likely to develop breast cancer than those who had never smoked. Women who once smoked but then kicked the habit were still 7% more at risk.The results held true even after accounting for alcohol cons...
Source: Guardian Unlimited Science - March 19, 2014 Category: Science Tags: The Guardian United States World news Health Smoking Medical research Society Cancer UK news Breast cancer Science Source Type: news

Esophageal Cancer
Title: Esophageal CancerCategory: Diseases and ConditionsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 3/14/2014 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - March 14, 2014 Category: Cancer & Oncology Source Type: news

Role of Human Papillomaviruses in Esophageal CarcinomaRole of Human Papillomaviruses in Esophageal Carcinoma
Studies have shown that HPV increases the risk of esophageal squamous cell carcinoma at least threefold. What impact could vaccines have on prevention? Future Virology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 11, 2014 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news

New AGA/GCF research grant to fund exploration of the development of gastric cancer
(American Gastroenterological Association) The American Gastroenterological Association (AGA) Research Foundation and the Gastric Cancer Foundation are pleased to announce that the first AGA-Gastric Cancer Foundation Research Scholar Award in Gastric and Esophageal Cancer will support Mohamed El-Zaatari, Ph.D., from University of Michigan, as he conducts research into the role of myeloid cells in the transition from chronic inflammation to gastric pre-neoplasia. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 11, 2014 Category: Global & Universal Source Type: news

Alcohol, smoking and obesity fuel 'alarming' global cancer surge
World Health Organisation experts issue timebomb warning and say key is prevention, possibly including tax on sugared drinksA concerted global effort to tackle the causes of cancer linked to lifestyle, such as alcohol abuse, sugar consumption and obesity, has been urged on Monday by the World Health Organisation as it predicted that the number of new cases could soar by 70% to nearly 25 million a year over the next two decades.Half of these cases are preventable, says the UN's public health arm in its World Cancer Report, because they are linked to lifestyle. It is implausible to think we can treat our way out of the disea...
Source: Guardian Unlimited Science - February 4, 2014 Category: Science Authors: Sarah Boseley Tags: The Guardian Obesity News Health Smoking Medical research Society Cancer UK news Alcohol Science Source Type: news

GERD: High-Risk Patients Get Endoscopic Short ShriftGERD: High-Risk Patients Get Endoscopic Short Shrift
Patients with gastroesophageal reflux disease (GERD) who are at highest risk for Barrett esophagus or cancer are less likely to undergo diagnostic endoscopy. Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - January 27, 2014 Category: Gastroenterology Tags: Gastroenterology News Source Type: news