Moving forward with dementia: an explorative cross-country qualitative study into post-diagnostic experiences
CONCLUSION: Across countries, formal support and support from friends and family are crucial for people with dementia and caregivers to come to terms with dementia and maintain carer wellbeing to ultimately live well with dementia.PMID:38656033 | DOI:10.1080/13607863.2024.2342968 (Source: Aging and Mental Health)
Source: Aging and Mental Health - April 24, 2024 Category: Geriatrics Authors: Maud Hevink Iris Linden Marjolein de Vugt Henry Brodaty Lee-Fay Low Lyn Phillipson Yun-Hee Jeon Meredith Gresham Shelly Doucet Alison Luke Isabelle Vedel Carrie McAiney Dorota Szcze śniak Maria B łaszkiewicz Joanna Rymaszewska Frans Verhey Claire Wolfs Source Type: research

< em > Ginkgo biloba < /em > and Its Chemical Components in the Management of Alzheimer's Disease
Am J Chin Med. 2024 Apr 24:1-42. doi: 10.1142/S0192415X24500277. Online ahead of print.ABSTRACTThe pathogenesis of Alzheimer's disease (AD), a degenerative disease of the central nervous system, remains unclear. The main manifestations of AD include cognitive and behavioral disorders, neuropsychiatric symptoms, neuroinflammation, amyloid plaques, and neurofibrillary tangles. However, current drugs for AD once the dementia stage has been reached only treat symptoms and do not delay progression, and the research and development of targeted drugs for AD have reached a bottleneck. Thus, other treatment options are needed. Bioa...
Source: The American Journal of Chinese Medicine - April 24, 2024 Category: Complementary Medicine Authors: Yong Peng Quan Chen Ya-Hui Xue Hong Jin Shu Liu Miao-Qiao Du Shun-Yu Yao Source Type: research

Adaptive immune changes associate with clinical progression of Alzheimer's disease
CONCLUSIONS: Our findings illustrate significant peripheral immune alterations associated with both early and late clinical stages of AD, emphasizing the necessity for further investigation into how these changes influence underlying brain pathology.PMID:38658964 | DOI:10.1186/s13024-024-00726-8 (Source: Atherosclerosis)
Source: Atherosclerosis - April 24, 2024 Category: Cardiology Authors: Lynn van Olst Alwin Kamermans Sem Halters Susanne M A van der Pol Ernesto Rodriguez Inge M W Verberk Sanne G S Verberk Danielle W R Wessels Carla Rodriguez-Mogeda Jan Verhoeff Dorine Wouters Jan Van den Bossche Juan J Garcia-Vallejo Afina W Lemstra Maarte Source Type: research

Communicating visit information to family caregivers: How does method matter? A national survey
This study sought to determine whether mode of receiving clinic visit information (speaking with the patient, attending the visit, or using an after-visit summary [AVS]) was associated with changes in caregiver burden, caregiver preparedness, and the positive aspects of caregiving.METHODS: Cross-sectional web-based survey of a national sample of adult family caregivers. Multiple linear regression models determined associations between communication modes and caregivers' burden, preparedness, and positive aspects of caregiving, adjusting for sociodemographic covariates.RESULTS: Respondents (N = 340) were mostly male (58%), ...
Source: Palliative and Supportive Care - April 24, 2024 Category: Palliative Care Authors: Reed W R Bratches Noah Z Freundlich J Nicholas Odom A James O'Malley Paul J Barr Source Type: research

Adaptive immune changes associate with clinical progression of Alzheimer ’s disease
Alzheimer ’s disease (AD) is the most frequent cause of dementia. Recent evidence suggests the involvement of peripheral immune cells in the disease, but the underlying mechanisms remain unclear. (Source: Molecular Neurodegeneration)
Source: Molecular Neurodegeneration - April 24, 2024 Category: Neurology Authors: Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodriguez, Inge M. W. Verberk, Sanne G. S. Verberk, Danielle W. R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff, Dorine Wouters, Jan Van den Bossche, Juan J. Garcia-Vallejo, Tags: Research article Source Type: research

Adherence to Online Interventions for Family Caregivers of People with Dementia: A Meta-analysis and Systematic Review
With the rapid increase in the proportion of people with dementia, the number of family caregivers providing unpaid care and support is also growing worldwide. Family caregivers are an essential pillars of dementia management efforts, as they reduce the economic cost of care and play an important role in supporting the quality of life in people with dementia [2]. While caregiving can provide a sense of fulfilment, the burden of caregiving can also cause significant psychological challenges [3]. (Source: The American Journal of Geriatric Psychiatry)
Source: The American Journal of Geriatric Psychiatry - April 24, 2024 Category: Geriatrics Authors: Golnaz L. Atefi, Wei Qi Koh, Gianna Kohl, Mohammad Seydavi, Joshua K. Swift, Mehdi Akbari, Marjolein E. deVugt Tags: Clinical Review Article Source Type: research

A qualitative study of informal caregiver perceptions of the benefits of an early dementia diagnosis
Current and former dementia policies in the United Kingdom (UK) recommend diagnosing dementia early, or as close to the onset of symptoms as possible. Informal caregivers play an important role in initiating t... (Source: BMC Health Services Research)
Source: BMC Health Services Research - April 24, 2024 Category: General Medicine Authors: Elyse Couch, Melissa Co, Christopher P. Albertyn, Matthew Prina and Vanessa Lawrence Tags: Research Source Type: research

Understanding the influence of different proxy perspectives in explaining the difference between self-rated and proxy-rated quality of life in people living with dementia: a systematic literature review and meta-analysis
ConclusionDifferent proxy perspectives affect the ratings of QoL, whereby adopting a proxy-proxy QoL perspective has a higher inter-rater gap in comparison with the proxy-patient perspective. (Source: Quality of Life Research)
Source: Quality of Life Research - April 24, 2024 Category: Health Management Source Type: research

Sensors, Vol. 24, Pages 2691: The Impact of Dual-Tasks and Disease Severity on Posture, Gait, and Functional Mobility among People Living with Dementia in Residential Care Facilities: A Pilot Study
Yanbin Dong Gait speed and timed-up-and-go (TUG) predict cognitive decline, falls, and mortality. Dual-tasks may be useful in cognitive screening among people living with dementia (PWD), but more evidence is needed. This cross-sectional study aimed to compare single- and dual-task performance and determine the influence of dementia severity on dual-task performance and interference. Thirty PWD in two residential care facilities (Age: 81.3 &amp;plusmn; 7.1 years; Montreal Cognitive Assessment: 10.4 &amp;plusmn; 6.0 points) completed two trials of single- (feet apart) and dual-task posture (feet apart while cou...
Source: Sensors - April 24, 2024 Category: Biotechnology Authors: Deborah A Jehu Ryan Langston Richard Sams Lufei Young Mark Hamrick Haidong Zhu Yanbin Dong Tags: Article Source Type: research

"I'm not a risk taker": Risk Perceptions of Nursing Home Residents With Dementia
DISCUSSION: Results suggest NH residents with ADRD can express risk surrounding their preferences and should be encouraged to participate in discussions about their health and safety.PMID:38651790 | DOI:10.1097/WAD.0000000000000616 (Source: Alzheimer Disease and Associated Disorders)
Source: Alzheimer Disease and Associated Disorders - April 23, 2024 Category: Psychiatry Authors: Liza L Behrens Hannah L Anderson Kal éi H Kowalchik Jacqueline Mogle Joanne Roman Jones Kimberly Van Haitsma Nancy Hodgson Marie Boltz Source Type: research

Commentary on: physical activity and exercise for mild cognitive impairment and dementia: a collaborative international guideline
In conclusion, there is limited evidence on the beneficial role of physical activity and exercise in preserving cognitive functions in subjects with normal cognition, MCI or dementia. The guidelines support the promotion of physical activity based on the beneficial effects on almost all facets of health.PMID:38652380 | PMC:PMC11039492 | DOI:10.1007/s40520-024-02747-1 (Source: Aging Clinical and Experimental Research)
Source: Aging Clinical and Experimental Research - April 23, 2024 Category: Geriatrics Authors: Nicola Veronese Pinar Soysal Mario Barbagallo Susan D Shenkin Terence J Quinn Source Type: research

"I'm not a risk taker": Risk Perceptions of Nursing Home Residents With Dementia
DISCUSSION: Results suggest NH residents with ADRD can express risk surrounding their preferences and should be encouraged to participate in discussions about their health and safety.PMID:38651790 | DOI:10.1097/WAD.0000000000000616 (Source: Alzheimer Disease and Associated Disorders)
Source: Alzheimer Disease and Associated Disorders - April 23, 2024 Category: Psychiatry Authors: Liza L Behrens Hannah L Anderson Kal éi H Kowalchik Jacqueline Mogle Joanne Roman Jones Kimberly Van Haitsma Nancy Hodgson Marie Boltz Source Type: research

Commentary on: physical activity and exercise for mild cognitive impairment and dementia: a collaborative international guideline
In conclusion, there is limited evidence on the beneficial role of physical activity and exercise in preserving cognitive functions in subjects with normal cognition, MCI or dementia. The guidelines support the promotion of physical activity based on the beneficial effects on almost all facets of health.PMID:38652380 | PMC:PMC11039492 | DOI:10.1007/s40520-024-02747-1 (Source: Aging Clinical and Experimental Research)
Source: Aging Clinical and Experimental Research - April 23, 2024 Category: Geriatrics Authors: Nicola Veronese Pinar Soysal Mario Barbagallo Susan D Shenkin Terence J Quinn Source Type: research