Mechanical ventilation in older adults with dementia: opportunities to promote goal-concordant care
CONCLUSION: Future efforts to promote goal-concordant care surrounding mechanical ventilation use for people living with dementia should involve identifying barriers to goal-concordant care in pre-hospital settings, assessing the timeliness of in-hospital GOCD, and developing strategies for in-the-moment crisis communication across settings.PMID:38685288 | DOI:10.1016/j.jpainsymman.2024.04.021 (Source: Pain Physician)
Source: Pain Physician - April 30, 2024 Category: Anesthesiology Authors: Lauren R Pollack Jamie T Nomitch Lois Downey Sudiptho R Paul May J Reed Alison M Uyeda Whitney A Kiker Danae G Dotolo Elizabeth Dzeng Robert Y Lee Ruth A Engelberg Erin K Kross Source Type: research

Experimental laboratory models as tools for understanding modifiable dementia risk
Alzheimers Dement. 2024 Apr 30. doi: 10.1002/alz.13834. Online ahead of print.ABSTRACTExperimental laboratory research has an important role to play in dementia prevention. Mechanisms underlying modifiable risk factors for dementia are promising targets for dementia prevention but are difficult to investigate in human populations due to technological constraints and confounds. Therefore, controlled laboratory experiments in models such as transgenic rodents, invertebrates and in vitro cultured cells are increasingly used to investigate dementia risk factors and test strategies which target them to prevent dementia. This re...
Source: The Journal of Alzheimers Association - April 30, 2024 Category: Psychiatry Authors: Duncan Sinclair Alison J Canty Jenna M Ziebell Adele Woodhouse Jessica M Collins Sharn Perry Eddy Roccati Maneesh Kuruvilla Jacqueline Leung Rachel Atkinson James C Vickers Anthony L Cook Anna E King Source Type: research

Quality Improvement Project to Increase Well-Being for Dementia Residents
The aim of this project was to implement a program to reduce the use of antipsychotic drugs and to decrease the number of avoidable transfers to inpatient psychiatric hospitals (IPHs) while enhancing the care of long-term care (LTC) residents with living with dementia. (Source: Journal of the American Medical Directors Association)
Source: Journal of the American Medical Directors Association - April 30, 2024 Category: Health Management Authors: Angela Norman, Emile Snyder, Brooke Knapp Source Type: research

Implementing a Fall Prevention Program in a Dementia Care Unit
The purpose of this project was to reduce falls and fall-related injuries at a long-term care facility by fostering a safe environment. This project evaluated the feasibility and impact of staff education and hourly purposeful rounding on fall rates in the dementia care unit of a long-term care facility. (Source: Journal of the American Medical Directors Association)
Source: Journal of the American Medical Directors Association - April 30, 2024 Category: Health Management Authors: Angela N. Jennings, Letha M. Joseph Source Type: research

Treat or Not to Treat: Ethical Dilemma on Acute DVT
We present a case of such an ethical dilemma between a physician and family regarding a patient with severe dementia and an acute lower extremity DVT. (Source: Journal of the American Medical Directors Association)
Source: Journal of the American Medical Directors Association - April 30, 2024 Category: Health Management Authors: Ishani Patel, Amanda Lathia Source Type: research

Case of Creutzfeldt-Jakob: How barriers to diagnosis delay essential care
Creutzfeldt-Jakob Disease (CJD) is a fatal, rapidly-progressive dementia, caused by prion proteins. Changes in personality, mood, and motor function, are common in association with CJD. Often a diagnostic challenge, it relies on the clinical exam, EEG, and CSF findings. Therapy is centered around early, high-quality supportive care. (Source: Journal of the American Medical Directors Association)
Source: Journal of the American Medical Directors Association - April 30, 2024 Category: Health Management Authors: Mohammad Khandwala, Lea Buda, Kerry Sheets, Lawrence J. Kerzner Source Type: research

Considerations of Care in Dementia of Schizophrenia
With an aging population, there is increasing number of persons with schizophrenia and dementia in the post-acute and long-term care settings. By eighty years of age, the prevalence of dementia diagnoses is 70.2% in persons with schizophrenia, compared to 11.3% in persons without. This high rate posits unique care considerations in the post-acute and long-term care settings. These include balancing medication management for mood and behavior stability while minimizing adverse side effects such as tardive dyskinesia and metabolic syndrome, and optimizing non-pharmacological interventions to enhance quality of life and safet...
Source: Journal of the American Medical Directors Association - April 30, 2024 Category: Health Management Authors: Sara Shu, Paul Takahashi Source Type: research

Dementia and Neurosyphilis, Are We Honoring the Patient ’s Wishes?
Dementia (major neurocognitive disorder) is characterized by a decline in cognition severe enough to interfere with daily function and independence Syphilis is a chronic infection caused by treponema pallidum. Syphilis progresses into four stages if left untreated: primary, secondary, latent and tertiary. Tertiary syphilis is seen 1-30 years after primary infection. This inflammatory disease progresses as neurosyphilis or gummatous syphilis. Cerebrospinal fluid, meninges and vascular structures are involved in the early stages of neurosyphilis, while in the late stage; cerebral tissue and spinal cord are affected. (Source:...
Source: Journal of the American Medical Directors Association - April 30, 2024 Category: Health Management Authors: Rodrigo A. Mojica, Vinita Shastri Source Type: research

Benefits of Multi-disciplinary Management in a Patient with Mixed Dementia
Vascular and neurodegenerative disorders frequently present as mixed dementia phenotype. The most common type of mixed dementia is Alzheimer ’s Dementia (AD) with vascular dementia. Dementia symptoms can develop at an earlier age when AD and vascular pathologies are both present. AD occurs with the accumulation of amyloid beta into fibrillar plaques and hyperphosphorylated tau into paired helical filament neurofibrillary tangles. Beta- amyloid Positron Emission Tomography (β-PET) can help establish AD diagnosis, as amyloid-beta deposition is a central pathophysiological marker of Alzheimer disease. (Source: Journal of t...
Source: Journal of the American Medical Directors Association - April 30, 2024 Category: Health Management Authors: Jazmine Duran, Arlen Tucker, Nirmala Bangalore Source Type: research

Rehabilitation Intensity and Successful Discharge in Persons with Dementia
Audiology, speech-language therapy, and occupational therapy (OSLA) can address functional deficits of dementia, but we do not know this set of services ’ effect on successful discharge after heart failure hospitalization in persons living with dementia. We hypothesize that increased OSLA time was associated with successful discharge home from skilled nursing facilities (SNFs) in Veterans with dementia (VwD) after heart failure (HF) hospitalizatio n. (Source: Journal of the American Medical Directors Association)
Source: Journal of the American Medical Directors Association - April 30, 2024 Category: Health Management Authors: Thomas A. Bayer, Lan Jiang, Mriganka Singh, Thomas Nubong, Zachary Kunicki, Julia Browne, John McGeary, Catherine Kelso, Wen-Chih Wu, James L. Rudolph Source Type: research

Nursing Home Profit Status and Pain Among Residents with Dementia
Pain is highly prevalent among nursing home (NH) residents with dementia. Estimates suggest 35-80% of NH residents with dementia experience pain and 20% of residents in pain do not receive analgesics. Pain has been identified as a quality indicator used to measure and monitor NH performance. There is growing attention focused on the role of NH ownership profit status in the context of quality and delivery of care. However, there is limited research on the role of profit status in the management of pain among residents with dementia. (Source: Journal of the American Medical Directors Association)
Source: Journal of the American Medical Directors Association - April 30, 2024 Category: Health Management Authors: Sorah Levy, Sarah D. Holmes, Barbara Resnick Source Type: research

Memory Center Care and Behavioral and Psychological Symptoms of Dementia
It is estimated that more than 90% of individuals with dementia experience agitation, aggression, psychosis, sleep or appetite changes, apathy, hallucinations and other Behavioral and Psychological Symptoms of Dementia (BPSD). Severe BPSD symptoms are associated with high levels of patient and caregiver distress, as well as with adverse outcomes and increased use of health care resources. Memory care centers offer structured daily activities using music, arts, cognitive and physical exercise and interactive tablets (iPads) which can help manage BPSD symptoms. (Source: Journal of the American Medical Directors Association)
Source: Journal of the American Medical Directors Association - April 30, 2024 Category: Health Management Authors: Alyssa Alicea, John Naumovski, Nicole Morgan Source Type: research

Examining Meaningful Activity Engagement for Residents in Assisted Living (MAC-4-BSD)
Engagement in meaningful activity is beneficial for residents with dementia and is associated with improved mental health, feelings of social connectedness, and quality of life. Meaningful activity refers to activities that provide meaning and value to the person and are tailored to individualized interests and preferences. There is limited research that explores factors that influence engagement in meaningful activity for residents with dementia in assisted living settings. The purpose of this study was to examine factors associated with engagement in meaningful activity among residents with dementia in assisted living. (...
Source: Journal of the American Medical Directors Association - April 30, 2024 Category: Health Management Authors: Sarah D. Holmes, Susan Scherr, Erin O'Brien, Sorah Levy, Elizabeth Galik, Barbara Resnick Source Type: research

COVID-19 Pandemic and Stroke Care in Patients With Dementia Compared to Other Stroke Patients
The primary objective of this study was to examine the impact of the COVID-19 pandemic on the quality of stroke care for patients with preexisting dementia, compared with patients who had only stroke. The secondary aim was to investigate how the quality of stroke care changed during the pandemic and post-pandemic periods compared with the pre-pandemic period in patients with preexisting dementia. (Source: Journal of the American Medical Directors Association)
Source: Journal of the American Medical Directors Association - April 30, 2024 Category: Health Management Authors: Tamar Abzhandadze, Minh Tuan Hoang, Minjia Mo, Shayan Mostafaei, Pol Grau Jurado, Hong Xu, Kristina Johnell, Mia Von Euler, Maria Eriksdotter, Sara Garcia-Ptacek Tags: Original Study Source Type: research

Oral anticoagulants and cognitive impairment in patients with atrial fibrillation: A systematic review with meta-analysis and trial sequential analysis
This systematic review assesses the likelihood of developing dementia and cognitive impairment in patients with atrial fibrillation (AF) receiving non-vitamin K antagonist oral anticoagulants (NOACs) as opposed to vitamin K antagonists (VKAs). (Source: Thrombosis Research)
Source: Thrombosis Research - April 30, 2024 Category: Hematology Authors: Kun-Han Lee, Jiunn-Tyng Yeh, Meng-Lun Wu, Wan-Yu Yeh, Gregory Y.H. Lip, Chern-En Chiang, Chen-Huan Chen, Hao-Min Cheng Source Type: research