The Role of Immune Aging in Neurodegenerative Conditions
The research community has come to see chronic inflammation and other age-related immune system dysfunctions as an important aspect of neurodegenerative conditions. Inflammation in the short term is necessary for defense against pathogens and regeneration following injury. Unresolved, constant inflammation is harmful to tissue structure and function, however, changing cell behavior for the worse. In brain tissue, the effects of inflammatory signaling on the behavior of innate immune cells called microglia appears particularly important. Neurogenerative conditions are characterized by activated microglia. These microglia ar...
Source: Fight Aging! - April 23, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
What The Decade Of Your Birth Reveals About Your Brain Size (M)
The decade you were born in may shape not just your life, but your brain size and dementia risk. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - April 23, 2024 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Neuroscience subscribers-only Source Type: blogs
Dementia
Clinical psychologist John Gartnerpulls out his Ph.D. to tell the world what ought to be obvious. Donald J. Trump has fairly advanced and rapidly progressing dementia. Believe me, I know what dementia looks like and I don ' t need a degree in psychology to tell you, but for some inexplicable reason the world wants to turn a blind eye. The New York Times ran at least one story every day for a couple of months (maybe a slight exaggeration, but also maybe not) telling us that Joe Biden is old, and the next day that he ' s still old, and the next day that he ' s still old . . . Every time he forgot a name or got a date w...
Source: Stayin' Alive - April 23, 2024 Category: American Health Source Type: blogs
Weekly Roundup – April 20, 2024
Welcome to our Healthcare IT Today Weekly Roundup. Each week, we’ll be providing a look back at the articles we posted and why they’re important to the healthcare IT community. We hope this gives you a chance to catch up on anything you may have missed during the week.
The Impact of the Technology Driving the Evolution of Healthcare at Home. Our latest question for the Healthcare IT Today community focused on the impact of care at home. Key value propositions included risk assessment, chronic condition management, and support for mental health. Read more…
A Look at the Hospital Room of the Future at Tampa General...
Source: EMR and HIPAA - April 20, 2024 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Healthcare IT Today Weekly Roundup Source Type: blogs
The Vitamin Deficiency Linked to Moodiness, Lack Of Motivation And Tiredness
The vitamin may have a direct effect on the brain and has also been linked to Parkinson's disease and dementia. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - April 18, 2024 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Mental Health Nutrition Source Type: blogs
Immortal Puppy Also Has Remote Monitoring Capabilities
Tombot’s AI-powered robotic puppy companion is more than just an emotional support animal, through an array of sensors it can also remotely monitor patients. The company is planning to have a beta version available soon with full production later in 2024.
There were many impressive technologies and digital solutions on display at #ViVE2024, but by far the more impressive (and cutest) was the one from a company called Tombot. They have an interactive, fully automated, emotional support animal that addresses the behavioral and psychological needs of patients with Dementia.
Healthcare IT Today got a preview of their robot f...
Source: EMR and HIPAA - April 15, 2024 Category: Information Technology Authors: Colin Hung Tags: Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System Telemedicine and Remote Monitoring Dementia emotional support Remote Patient Monitoring robot dog RPM support animal Tom Stevens Tombot Source Type: blogs
Fight Aging! Newsletter, April 15th 2024
In conclusion, although several clinical trials targeting SnCs are ongoing, various questions about the biology of SnCs remain open, resulting in a gap between molecular and cellular data. Concerning the need, initiatives such as SenNet aiming to create openly accessible atlases of SnCs should contribute enormously to the area. Advances in understanding the subcellular structure, the heterogeneity, and the dynamics of SnCs require the integration of molecular and cellular techniques with data analysis packages to evaluate high throughput evidence from microscopy and flow cytometry. It is also necessary to develop new equip...
Source: Fight Aging! - April 14, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Weekly Roundup – April 13, 2024
Welcome to our Healthcare IT Today Weekly Roundup. Each week, we’ll be providing a look back at the articles we posted and why they’re important to the healthcare IT community. We hope this gives you a chance to catch up on anything you may have missed during the week.
Exploring the Intersection of Patients and AI at OpenNotes Lab. Liz Salmi and Dr. Chethan Sarabu talked to Colin Hung about applying OpenNotes’ expertise in research, advocacy, and innovation to studying many aspects of AI, including algorithmic bias, generative AI, and ambient clinical voice. Read more…
Connecting Healthcare Clouds and Simpl...
Source: EMR and HIPAA - April 13, 2024 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Healthcare IT Today Weekly Roundup Source Type: blogs
Dump Punts
Apparently realizing that they were caught on the horns, as it were, the dumpsters handlers wrote a statement for him in which he tried to split the baby by saying that abortion policy should be left entirely up to the states. Presumably he agreed to this although his dementia is too far advanced for him to have written the statement.The whole issue has never been anything but opportunism for him. He proclaimed himself to be a strong supporter of abortion rights until he decided to run for president as a Republican, and then he had a very difficult time articulating exactly what he thought about the entire question until t...
Source: Stayin' Alive - April 8, 2024 Category: American Health Source Type: blogs
Linus Health Acquires Aural Analytics
Purchase Expands Linus Health’s Cognitive Assessment Capabilities
Linus Health, a digital health company enabling early detection of Alzheimer’s and other dementias, today announced it has acquired Aural Analytics, a leader in clinical-grade speech analytics. The deal includes Aural Analytics’ assets, including its technology and intellectual property.
With the acquisition of Aural Analytics, Linus Health, the leader in multimodal cognitive assessments, has added clinical-grade speech analytics to its platform. This allows Linus Health to further enable researchers and clinicians to identify cognitive impairment and ...
Source: EMR and HIPAA - April 8, 2024 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Alvaro Pascual-Leone Aural Analytics David Bates Digital Cognition Technologies Health IT Acquisitions Healthcare M&A Kinesis Health Technologies Linus Health Source Type: blogs
Dysfunction of the Glymphatic System Correlates with Faster Progression of Alzheimer's Disease
The glymphatic system is one of the pathways for drainage of cerebrospinal fluid from the brain to the body. This drainage is necessary to remove metabolic waste from the brain, and there is good evidence for reduced outflow of cerebrospinal fluid to lead to the development of neurodegenerative conditions. The work here adds to this body of evidence, showing that impaired flow of cerebrospinal fluid through the glymphatic system correlates with later severity of Alzheimer's disease.
The glymphatic system is an essential fluid-clearance system in the brain. The highly organized cerebrospinal fluid (CSF) transport s...
Source: Fight Aging! - April 8, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, April 8th 2024
In this study, we tested a stem cell secretome product, which contains extracellular vesicles and growth factors, cytoskeletal remodeling factors, and immunomodulatory factors. We examined the effects of 4 weeks of 2×/week unilateral intramuscular secretome injections (quadriceps) in ambulatory aged male C57BL/6 mice (22-24 months) compared to saline-injected aged-matched controls.
Secretome delivery substantially increased whole-body lean mass and decreased fat mass, corresponding to higher myofiber cross-sectional area and smaller adipocyte size, respectively. Secretome-treated mice also had greater whole-bod...
Source: Fight Aging! - April 7, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Skin Biopsy as an Approach to Diagnose Parkinson's Disease
Researchers here demonstrate that the presence of phosphorylated α-synuclein in a skin biopsy is a good indicator of the presence of Parkinson's disease and other synucleinopathies. A skin biopsy is a more invasive procedure than most people want to undergo, but a greater ability to diagnose progressive diseases in their early stages will nonetheless tend to encourage the development of a greater ability to manage, treat, and avoid the later stages.
Affecting an estimated 2.5 million people in the United States, the synucleinopathies include Parkinson's disease (PD), dementia with Lewy bodies (DLB), multiple syst...
Source: Fight Aging! - April 5, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Transient Pockets of Hypoxia in the Mammalian Brain
Evidence suggests that the mammalian brain is operating at the very edge of its capacity, supplied with just enough oxygen and nutrients to barely get by. That exercise produces measurable short-term gains in cognitive function, while blood flow is increased, is one point in favor of this view. Another is provided here, in which researchers note that it is entirely normal to observe transient areas of hypoxia in the brain at rest, and that the occurrence of these regions is diminished by the increased blood flow of exercise. It is an open question as to what to do with this finding: we can imagine future technologies that ...
Source: Fight Aging! - April 5, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Does Herpes Simplex Virus cause Alzheimer ’ s Disease?
by Gertrud U. Rey Alzheimer’s Disease (AD) is a neurodegenerative disorder and the most common form of dementia. Although its exact cause is unclear, an increasing body of evidence suggests that an infection with herpes simplex virus (HSV) may contribute to onset of AD later in life. Both types of HSV (HSV-1 and HSV-2) infect … Does Herpes Simplex Virus cause Alzheimer’s Disease? Read More » (Source: virology blog)
Source: virology blog - April 4, 2024 Category: Virology Authors: Gertrud U. Rey Tags: Basic virology Gertrud Rey alzheimer's disease amyloid beta amyloid plaque APOE-ɛ4 association causation cognitive defect cognitive function correlation dementia herpes simplex virus herpes simplex virus 1 herpesvirus mechan Source Type: blogs
