New Textbook Chapter on Pressure Injuries & Chronic Wounds
I am thrilled that my chapter entitled Pressure Injury and Chronic Wounds was just published in a major new reference work. The textbook is entitled Geriatric Medicine: A Person Centered Evidence Based Approach and is available on Springerlink. My chapter is illustrated by photos taken over years in practice, and illustrations that demonstrate pressure injury staging and aging skin. This chapter is part of a large multidisciplinary reference work with over 70 peer-reviewed chapters designed to present a comprehensive and state-of-the-art update that incorporates existing literature with clinical experience.  Geriatric med...
Source: Jeffrey M. Levine MD | Geriatric Specialist | Wound Care | Pressure Ulcers - November 5, 2023 Category: Geriatrics Authors: Jeffrey M Levine Tags: Featured Medical Articles Geriatric Medicine Long-Term Care Pressure Injuries & Wound Care Publications aging skin bedsore bedsores decubiti decubitus ulcer elder abuse end-of-life care eschar geriatrics gerontology Healthcar Source Type: blogs

Fight Aging! Newsletter, November 6th 2023
This study aimed to gather valuable insights from pharmaceutical experts and healthcare practitioners regarding the potential and challenges of translating senolytic drugs for treatment of vascular aging-related disorders. This study employed a qualitative approach by conducting in-depth interviews with healthcare practitioners and pharmaceutical experts. Participants were selected through purposeful sampling. Thematic analysis was used to identify themes from the interview transcripts. A total of six individuals were interviewed, with three being pharmaceutical experts and the remaining three healthcare practitioners. ...
Source: Fight Aging! - November 5, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Vitamin-Like Deficiency Linked To Alzheimer ’ s Disease
Inadequate daily intake of this vitamin-like compound can lead to an enlarged heart, liver damage, weight gain as well as Alzheimer’s disease. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - November 4, 2023 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Dementia Source Type: blogs

2 Portions Of This Food Halves Risk Of Memory Loss
Any variety may well have the beneficial effect as they all contain an antioxidant called ergothioneine. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - November 3, 2023 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Dementia Source Type: blogs

The Alzheimer ’s Early Warning Sign Most People Don ’ t Know
Damage to the brain can occur 15 to 20 years before the clinical symptoms appear. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - November 2, 2023 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Dementia Source Type: blogs

The Vitamin Deficiency That Triples Dementia Risk
Memory problems are one of the key symptoms of dementia. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - October 30, 2023 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Dementia Source Type: blogs

Gingivitis Bacteria Causes Harms in the Heart, Impairing Already Poor Recovery from Heart Attack
Inflammatory periodontal disease is caused by a specific bacterial species. The bacteria can use damaged gums to enter the bloodstream. It is thought that its ability to provoke inflammation can then contribute to cardiovascular disease and dementia, though the size of the effect is up for debate. Along these lines, researchers here show that periodontal bacteria can worsen the consequences of a heart attack, impairing the already limited ability of the heart to regenerate and restore function following injury. Heart attacks occur when blood flow in the coronary arteries is blocked, resulting in an inadequate supp...
Source: Fight Aging! - October 30, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, October 30th 2023
In conclusion, reported adherence to a healthy lifestyle is associated with reduced risk of all-cause and cause-specific mortality. Adherence to all four lifestyle factors resulted in the strongest protection. « Back to Top (Source: Fight Aging!)
Source: Fight Aging! - October 29, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Study: Playing board games like Chess, Mahjong, Go, helps slow cognitive decline as we age (but with clear differences in neurobiology and function)
Conclusions: Traditional board games may slow global cognitive decline and improve the quality of life in elderly subjects. Different games have varying impacts on specific cognitive domains, possibly mediated by functional and biological factors. The Study in Context: Study: For better memory and thinking skills at age 70 (and beyond), play cards and board games from age 11 How learning changes your brain Solving the Brain Fitness Puzzle Is the Key to Self-Empowered Aging The post Study: Playing board games like Chess, Mahjong, Go, helps slow cognitive decline as we age (but with clear differences in neurobio...
Source: SharpBrains - October 25, 2023 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Education & Lifelong Learning aging Alzheimer’s Disease BDNF chess cognition cognitive decline Cognitive-impairment dementia Go Mahjong neurobiology primary prevention recreational games secondary preve Source Type: blogs

Sex Differences in Cholinergic Neurons in the Context of Alzheimer's Disease
Why are most Alzheimer's disease patients women? The longer female life expectancy is not enough to explain all of this difference, so researchers investigate the underlying biochemical differences between sexes in search of an explanation. The goal is to use this difference in outcomes to identify mechanisms that are important to disease progression in all humans. One might look at a recent paper on microglial biochemistry, for example, and compare with this examination of the activity of cholinergic neurons. It is worth noting that the two are linked, with cholinergic neurons likely regulating microglial behavior to some...
Source: Fight Aging! - October 24, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The #1 Avoidable Risk Factor For Early-Onset Dementia
The damage done by this risk factor was particularly striking for early-onset dementia: that which occurs before 65-years-old. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - October 21, 2023 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Alcohol Dementia Source Type: blogs

Questions grow about the validity and usefulness of direct-to-consumer blood tests for Alzheimer ’s Disease
For the first time, people worried about their risk of Alzheimer’s disease can go online, order a blood test, and receive results in the privacy of their homes. This might seem appealing on the surface, but the development has Alzheimer’s researchers and clinicians up in arms. The Quest Diagnostics blood test, AD-Detect, measures elevated levels of amyloid-beta proteins, a signature characteristic of Alzheimer’s. Introduced in late July, the test is targeted primarily at people 50 and older who suspect their memory and thinking might be impaired and people with a family history of Alzheimer’s or genetic risks for t...
Source: SharpBrains - October 19, 2023 Category: Neuroscience Authors: Judith Graham at Kaiser Health News Tags: Brain/ Mental Health AD-Detect Alzheimer’s Alzheimer’s biomarker amyloid-beta proteins brain health brain pathology cognitive cognitive-symptoms mini-strokes neurology neuropsychologist Quest Diagnostics sleep apnea Source Type: blogs

Towards Inhibition of α-Synuclein Aggregation
We report that αS1-25 inhibits lipid-induced αS aggregation in a dose-dependent manner. αS1-25 functions by binding to lipids to prevent αS binding, with both αS and peptide requiring lipid for inhibition to occur. These findings present a potential mechanistic route for the treatment or prevention of PD. (Source: Fight Aging!)
Source: Fight Aging! - October 18, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

More Evidence for Impaired Hearing to Contribute to Cognitive Decline
In conclusion, cochlear implant use seems to boost cognitive trajectories in the first years after implantation. However, long-term prevention of dementia seems to need far more than restoration of hearing loss. (Source: Fight Aging!)
Source: Fight Aging! - October 16, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Fight Aging! Newsletter, October 16th 2023
In conclusion, a number of studies have shown that CD4+ Treg cells are crucial in the maintenance of peripheral tolerance and have an important role in the control of atherosclerosis-related inflammation. Therefore, Treg cells are a promising target of major research efforts focused on immune-modulating therapies against atherosclerosis. Developing anti-atherosclerotic Treg-based therapies faces challenges. However, rapid progress in genetic, epigenetic, and molecular aspects of cellular immunology gives hope for a fast-track solution. « Back to Top Delivering Senolytic Nanoparticles to Atheroscle...
Source: Fight Aging! - October 15, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs