Studies find growing evidence linking weight, physical activity, neuroplasticity and depression
Being overweight can cause depression — and exercise is an antidote, dual studies confirm (Runner’s World): A large-scale study from the University of Exeter has found ‘robust evidence’ that being overweight hikes up your risk of developing depression – but as fresh evidence confirms, logging your morning miles is one of the most effective ways to fight back. Exercise jolts your brain into action, and not just because of the endorphin high … ‘Obesity and depression are both major global health challenges, and our study provides the most robust evidence to date that higher BMI caus...
Source: SharpBrains - October 18, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health body mass index Brain-Plasticity depression depressive disorders generalized anxiety disorder metabolic health neuroplasticity obesity Physical-activity Physical-Exercise Transcranial-Magnetic-Stimulation Source Type: blogs

Six guidelines to navigate the Aduhelm controversy and (hopefully) help patients with Mild Cognitive Impairment and early-stage Alzheimer ’s Disease
The approval of a controversial new drug for Alzheimer’s disease, Aduhelm, is shining a spotlight on mild cognitive impairment — problems with memory, attention, language or other cognitive tasks that exceed changes expected with normal aging. After initially indicating that Aduhelm could be prescribed to anyone with dementia, the Food and Drug Administration now specifies that the prescription drug be given to individuals with mild cognitive impairment or early-stage Alzheimer’s, the groups in which the medication was studied. Yet this narrower recommendation raises questions. What does a diagnosis of mi...
Source: SharpBrains - October 13, 2021 Category: Neuroscience Authors: Kaiser Health News Tags: Brain/ Mental Health Aduhelm Alzheimer’s Disease attention-problems brain bleeding brain swelling cognitive problems dementia dementia specialists early-stage Alzheimer’s Food and Drug Administration language problems memory pr Source Type: blogs

Dr. Judith Beck on the future of cognitive therapy and psychotherapy
Dr. Awais Aftab: What do you think the future of psychotherapy is? What would you like it to be? Dr. Judith Beck: A number of years ago, a colleague asked my dad whether he expected cognitive therapy to eventually dominate the field of psychotherapy. He responded, “I hope good therapy eventually dominates the field of psychotherapy. Just good therapy.” My father has always said, and I agree, that if significant research demonstrates greater support for the theoretical framework and treatment of a different psychotherapy, then that psychotherapy should supplant CBT. So far that has not happened. To the contrary,...
Source: SharpBrains - October 11, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health cognitive-behavioral-therapy cognitive-therapy computer-assisted therapy Judith-Beck Psychiatric Times Psychotherapy therapists Source Type: blogs

The Federal Trade Commission (FTC) hardens data security rules for health apps and devices
FTC says it will fine digital health companies that don’t disclose data breaches (mobihealthnews): With data breaches on the rise, the FTC is looking to make health apps more accountable for telling patients when their data has been exposed. The FTC released a new statement specifying that all health apps that capture sensitive patient information notify users, the commission itself and in some cases the media when a security breach has compromised identifiable health data. If the company fails to do so it could face a fine of $43,792 per day of violation. The ruling is actually more than ten years old, but according...
Source: SharpBrains - October 7, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation data breaches devices digital health FTC health apps Health Breach Notification Rule health data personal health records security breach Source Type: blogs

Study: Personalized, closed-loop neuromodulation can (one day) become a “pacemaker for the brain”
This study points the way to a new paradigm that is desperately needed in psychiatry,” said Andrew Krystal, PhD, professor of psychiatry and member of the UCSF Weill Institute for Neurosciences. “We’ve developed a precision-medicine approach that has successfully managed our patient’s treatment-resistant depression by identifying and modulating the circuit in her brain that’s uniquely associated with her symptoms.” Previous clinical trials have shown limited success for treating depression with traditional deep brain stimulation (DBS), in part because most devices can only deliver consta...
Source: SharpBrains - October 5, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation biomarker brain circuit brain patterns brain stimulation closed-loop therapy deep-brain-stimulation neural biomarker neuromodulation neuropsychiatric pacemaker for the brain precision me Source Type: blogs

Welcome to the Ultimate Neuroscience Lab: Your Smartphone
Welcome to a new edition of SharpBrains’ e‑newsletter, featuring this time six scientific reports and industry resources plus a fun illusion. #1. Top 10 Mental Health Innovations to Watch: Special SciAm/ WEF report Hoping you enjoy the great series over at Scientific American and especially #7, titled Welcome to the Ultimate Neuroscience Lab: Your Smartphone, by Emory neuroethicist Karen Rommelfanger and our very own Álvaro Fernández Ibáñez. #2. Five thoughts to think about when thinking about the speed of thought The time it takes for all thoughts to occur is ultimately shaped by the ch...
Source: SharpBrains - September 30, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation adhd Aduhelm brain-teaser cognitive cognitive complaints dementia emotion regulation lifelong mental health lifelong-brain-health myelination Neurons neuroscience lab quick brain tea Source Type: blogs

Study: Self-guided sleep app Sleepio, combined with standard care for depression and anxiety, delivers better outcomes than standard care alone
Conclusions: Significant clinical benefit was associated with the introduction of an evidence-based digital sleep intervention alongside other mental health interventions for depression and anxiety. Widespread deployment was achieved with immediate availability, minimal additional clinical time or staff training. This approach provides a feasible and highly scalable model for improving mental health outcomes in clinical services. The Study in Context: The FDA clears Somryst, Pear’s digital therapeutic to treat chronic insomnia CVS Health: Cognitive behavioral therapy (CBT) apps may help you more than sleeping pills...
Source: SharpBrains - September 27, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation anxiety app Behaviour Research and Therapy Big Health cognitive behavioural therapy depression digital CBT digital cognitive behavioural therapy digital health insomnia insomnia DTx me Source Type: blogs

Quick brain teaser: What do you see? And, can you unsee it?
Please describe what you see up there. What about below, as the full scene appears? Once you have seen the face, can you unsee it and focus on the birds? Tough, right? Try counting them, that may help 🙂 More fun illusions and brain teasers: Where’s the baby? Test your brain and mind with these nine classic optical Illusions Top 25 fun Brain Teasers and Puzzles The post Quick brain teaser: What do you see? And, can you unsee it? appeared first on SharpBrains. (Source: SharpBrains)
Source: SharpBrains - September 23, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain Teasers brain teasers for adults brain teasers for teens brain-teaser illusion mind puzzles mind-teaser Source Type: blogs

Five thoughts to think about when thinking about the speed of thought
This article was originally published on The Conversation. News in Context: Award-winning image shows neuroimaging progress in a century Neuroplasticity as seen by one of its earliest scientist proponents: Neuroscience pioneer Santiago Ramón y Cajal Can you grow your hippocampus? Yes. Here’s how, and why it matters The post Five thoughts to think about when thinking about the speed of thought appeared first on SharpBrains. (Source: SharpBrains)
Source: SharpBrains - September 21, 2021 Category: Neuroscience Authors: The Conversation Tags: Brain/ Mental Health Education & Lifelong Learning cognitive electroencephalography functional magnetic resonance imaging movement myelination Neurons perception reaction-time speed of thought thinking thoughts Source Type: blogs

Study finds ADHD is associated with dementia
We examined the extent to which attention-deficit/hyperactivity disorder (ADHD), a neurodevelopmental disorder, is linked with Alzheimer’s disease (AD) and any dementia, neurodegenerative diseases, across generations… Results: Among relatives of 2,132,929 index persons, 3042 parents, 171,732 grandparents, and 1369 uncles/aunts had a diagnosis of AD. Parents of individuals with ADHD had an increased risk of AD (hazard ratio 1.55, 95% confidence interval 1.26–1.89). The associations attenuated but remained elevated in grandparents and uncles/aunts. The association for early-onset AD was stronger than late-...
Source: SharpBrains - September 16, 2021 Category: Neuroscience Authors: SharpBrains Tags: Attention & ADD/ADHD Brain/ Mental Health Alzheimers-disease attention-deficit/hyperactivity disorder cognitive cognitive decline cognitive-abilities dementia neurodegenerative-diseases Neurodevelopmental Source Type: blogs

Top 10 Mental Health Innovations to Watch: Special SciAm/ WEF report
Credit: Adobe The World Economic Forum’s Global Future Council on Mental Health, comprising some of the foremost leaders in mental health, technology, informatics, business, public policy and advocacy is publishing its selections for the Top 10 Innovations in Mental Health. The initiative is in partnership with Scientific American, which is publishing articles by these leaders on its website. Dr. Murali Doraiswamy, Council co-chair and professor of psychiatry at Duke University School of Medicine notes that “the council sifted through more than 60 nominations to pick novel solutions with the highest near-term p...
Source: SharpBrains - September 14, 2021 Category: Neuroscience Authors: World Economic Forum Tags: Brain/ Mental Health Technology & Innovation Analytics curricula esketamine Innovations physiological signals psychedelics scientific-american smartphones World Economic Forum Source Type: blogs

On uncertainty, stress, emotion regulation, and carpe diem
Rosaleda at Parque del Oeste in Madrid, Spain Ever since it began, the pandemic has been a crash course in uncertainty. Safe behaviors, school openings, vaccination timelines, the job market, new variants—these have all seemed to change on a weekly basis, threatening our sense of security and stability. Uncertainty is stressful and perhaps even harmful to our health, research suggests, and it can drive us to cling to our social groups to the exclusion of others. But a new study has uncovered a surprising upside to feeling uncertain: It might drive us to appreciate the little things in life. In one experiment, researc...
Source: SharpBrains - September 9, 2021 Category: Neuroscience Authors: Greater Good Science Center Tags: Brain/ Mental Health Education & Lifelong Learning emotion regulation Gratitude pandemic savoring Stress uncertainty Source Type: blogs

Study: Fewer than 1% of geriatric patients with cognitive complaints met Aduhelm research trial criteria. What can we expect about its real-world safety?
Biogen’s Aduhelm label far exceeds clinical trial population, study says. That could bring real-world surprises (Fierce Pharma): While the chatter surrounding Biogen’s controversial Alzheimer’s med Aduhelm has largely been centered on a pivotal Medicare reimbursement decision as of late, analysts are pointing to one new study that suggests there may be “room for surprises” when it comes to the treatment’s safety. In a note to clients on Wednesday, RBC Capital Markets analysts highlighted a recent study that applied Biogen’s publicly disclosed clinical trial inclusion criteria for A...
Source: SharpBrains - September 7, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health aducanumab Aduhelm Alzheimer's med American Geriatrics Society Biogen cognitive cognitive complaints FDA Medicare reimbursement undetected side effects Source Type: blogs

On cognitive reframing and biases, stress, mental health tech, Aduhelm backlash, Britney Spears, and more
Welcome to a new edition of SharpBrains’ e‑newsletter, featuring this time nine scientific reports and industry developments to help promote lifelong brain and mental health. #1. To lower stress levels and improve problem-solving, practice cognitive reframing instead of venting “… venting likely doesn’t soothe anger as much as augment it. That’s because encouraging people to act out their anger makes them relive it in their bodies, strengthening the neural pathways for anger and making it easier to get angry the next time around. Studies on venting anger (without effective feedback), whethe...
Source: SharpBrains - August 31, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Education & Lifelong Learning Alzheimer's drug Alzheimers-disease anger Behavioral Health beta-amyloid Biogen Brain Teasers brain-teaser Britney Spears cognitive cognitive biases cognitive reframing cogniti Source Type: blogs

Study examines common cognitive biases (have you tried this brain teaser?) and ways to mitigate them
Pic: Getty Images A fascinating new study, Tversky and Kahneman’s Cognitive Illusions: Who Can Solve Them, and Why?, probes into the cognitive “heuristics and biases” researched by Daniel Kahneman and Amos Tversky since the late 1960s. If you have never encountered the “Linda brain teaser” before, please give it a try: Linda is 31 years old, single, outspoken, and very bright. She majored in philosophy. As a student, she was deeply concerned with issues of discrimination and social justice, and also participated in anti-nuclear demonstrations. Which statement is more probable? (a) Linda is a b...
Source: SharpBrains - August 30, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain Teasers Brain/ Mental Health adults Bayesian reasoning brain-teaser cognitive cognitive biases cognitive illusion cognitive illusions cognitive-abilities cognitive-ability cognitive-bias free-brain-teasers Linda problem l Source Type: blogs

Headspace and Ginger merge to expand and scale up digital mental health
Headspace and Ginger are merging to form Headspace Health (TechCrunch): Meditation app Headspace this morning announced plans to merge with on-demand mental health service Ginger. Barring unforeseen regulatory roadblocks, the two companies will combine to form Headspace Health. The new organization would sport a combined value of $3 billion and a headcount of more than 800. The merger comes during accelerated usage of both parties, as a seemingly endless pandemic has put a strain on mental health across the globe and many have turned to virtual solutions to address the growing problem. … Ginger announced a $50 ...
Source: SharpBrains - August 25, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation Behavioral Health Calm Ginger Headspace Headspace Health meditation app mindfulness neurotechnologies on-demand mental healthcare psychiatry therapy Source Type: blogs

How to read, understand and write great medical research
These excellent tips are kindly shared by RK Sharma and HL Ogle, two medical students at the University of Exeter, aiming to clear up many of the inaccurate assumptions of how difficult publishing is and provide a clear guide for students to begin their own writing journeys. #1. Find your why: Evidence-based medicine means that these are vital skills, and it has long been thought that the habits should be learned from early on. #2. Play to your strengths and be realistic: A little bit of thought and planning at this stage will create a much friendlier introduction to research. Take a little time to reflect and think about ...
Source: SharpBrains - August 23, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health evidence-based-medicine how to read and understand how to remember what you read medical research read research tips Source Type: blogs

To lower stress levels (ours and others ’), practice cognitive reframing instead of venting
We all get upset from time to time—some of us more than others. Whether we’re sad about the loss of a loved one, angry at friends or family, or fearful about the state of the world, it often feels good to let it all out. That’s because sharing our emotions reduces our stress while making us feel closer to others we share with and providing a sense of belonging. When we open up our inner selves and people respond with sympathy, we feel seen, understood, and supported. But “sharing” covers a lot of different modes of communication. Are some healthier than others, over the long run? Science sugge...
Source: SharpBrains - August 19, 2021 Category: Neuroscience Authors: Greater Good Science Center Tags: Education & Lifelong Learning cognitive needs cognitive reframing emotional needs Emotions human-brain neural pathways Stress venting Source Type: blogs

Veterans Affairs won ’t cover Biogen’s new “Alzheimer’s drug” given concerns over safety and lack of evidence
VA Health System Won’t Cover Biogen’s Alzheimer’s Drug (The Wall Street Journal): The Department of Veterans Affairs won’t cover Biogen Inc.’s new Alzheimer’s drug, the latest rebuke of the controversial treatment since it was approved earlier this summer. The VA decided not add the drug, called Aduhelm, to its formulary list of available medicines because of the drug’s risk of causing serious side effects and a lack of evidence that it improves cognitive function, an agency spokeswoman said. The VA provides medical benefits to more than nine million veterans, and is the largest in...
Source: SharpBrains - August 16, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health aducanumab Aduhelm Alzheimer's drug Alzheimers-disease betaamyloid plaques Biogen cognitive-function FDA Formulary Healthcare-System improves cognitive function mild dementia mild-cognitive-impairment neuro Source Type: blogs

Neurotech start-up Paradromics raises $20M to address brain-related disorders via next-gen brain-computer interfaces
Neuralink Competitor Raises $20 Million for Brain Implants (Bloomberg): A competitor to Elon Musk’s Neuralink said it raised $20 million, enough to get it on track to introduce a new generation of powerful and tiny electrodes to the human brain. Paradromics Inc., founded in 2015 about a year ahead of Neuralink, is building brain-computer interfaces that could help people with disorders ranging from paralysis to speech impediments. “Once you start to realize that the best way to describe the brain is through data, you start to reframe a lot of classically hard-to-treat conditions,” said Matt Angle, chief e...
Source: SharpBrains - August 11, 2021 Category: Neuroscience Authors: SharpBrains Tags: Technology & Innovation brain implants brain-machine interface brain-related disorders BrainGate DARPA electrodes healthcare microelectronics Neuralink neuroscience Paradromics Prime Movers Lab Source Type: blogs

Debunking four myths about decision-making capacity to keep Britney Spears and others safe
This article was originally published on The Conversation. News in Context: What are cognitive abilities and how to boost them? Think twice before taking Aderall for cognitive enhancement: It may actually impair working memory and other cognitive abilities Study in China finds that retirement may accelerate cognitive decline, even for those with stable income The post Debunking four myths about decision-making capacity to keep Britney Spears and others safe appeared first on SharpBrains. (Source: SharpBrains)
Source: SharpBrains - August 9, 2021 Category: Neuroscience Authors: The Conversation Tags: Brain/ Mental Health Britney Spears conservatorship decision-making capacity ethics medication psychiatric psychiatric disorders Psychotherapy psychotic states schizophrenia Source Type: blogs

Alzheimer ’s & Dementia researchers challenge FDA ’s approval of Aduhelm given lack of evidence for beta-amyloid as a marker
Doctors Blast Biogen Alzheimer Approval as ‘Regulatory Failure’ (Bloomberg): Top researchers who advised the U.S. Food and Drug Administration on Biogen Inc.’s Alzheimer’s drug blasted the agency for approving it, calling the decision a “regulatory failure” that is “at odds with the evidence.” The New England Journal of Medicine opinion piece, signed by seven members of an advisory panel that opposed clearing Biogen’s Aduhelm, is another sign of persistent furor over the agency’s decision … The new commentary is signed by them and four other panel members, ...
Source: SharpBrains - August 5, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Aduhelm Alzheimer's drug Alzheimers-treatment beta-amyloid Biogen cognitive FDA approval surrogate Source Type: blogs

Integrating music, movement and stroke rehabilitation, MedRhythms raises $25M to develop and commercialize digital therapeutic
MedRhythms raises 25m to get patients back in tune after a stroke (TechCrunch): MedRhythms secured $25 million in Series B funding to advance its digital therapy platform aimed at measuring and improving someone’s ability to walk after they have experienced a neurologic injury or disease … Company co-founder and CEO Brian Harris was a neurologic music fellow at Spaulding Rehabilitation Hospital in Boston, treating people with stroke and brain deficits with music. He began getting questions from patients and families on how they could access similar care outside of the hospital. Not seeing a suitable alter...
Source: SharpBrains - August 2, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation brain deficits breakthrough device chronic stroke walking deficits digital therapeutics digital therapy platform electrophysiological entrainment neural circuitry neurologic disorders neur Source Type: blogs

Update: Promote brain plasticity by taking your daily exercise pill — physical and cognitive
By lordzg/ shutterstock.com Welcome to a new edition of SharpBrains’ e‑newsletter, featuring nine scientific reports and industry developments to help promote lifelong brain health. #1. A must-read, and must-practice: Promote brain plasticity and keep your mind at ease by taking your daily “exercise pill” #2. If cognitive stimulation came in a pill it’d be worth a quadrillion, give or take a few trillions: Study finds that cognitive activity in old age may delay the onset of dementia by 5 years #3. “A young child with low cognitive control is also more likely to develop anxiety later on in c...
Source: SharpBrains - July 30, 2021 Category: Neuroscience Authors: Alvaro Fernandez Tags: Brain/ Mental Health Education & Lifelong Learning SharpBrains Monthly eNewsletter Technology & Innovation Brain Teasers Brain-games Brain-Plasticity cognitive-control cognitive-stimulation EEG eMindful mindfulness apps neuroscienc Source Type: blogs

Evidence-based, employer-focused meditation program eMindful acquired by digital behavioral change firm Wondr Health
Riverside completes add-on investment to Wondr Health Platform (Private Equity Wire): The Riverside Company, a global private investor focused on the smaller end of the middle market, has invested in eMindful, a provider of evidence-based, mindfulness programmes for everyday life and chronic conditions. The investment is an add-on to Riverside’s Wondr Health (formerly Naturally Slim), a digital behavioral change company focused on weight management and preventing chronic disease within the employer-sponsored space. This partnership builds on the clinical expertise and outcomes of the Wondr and eMindful offerings, cre...
Source: SharpBrains - July 28, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation behavioral change behaviour change digital behavioral change disease management program eMindful employer meditation apps mindfulness Naturally Slim Riverside Company Wondr Health Source Type: blogs

AI-powered Woebot raises $90M to scale up digital self-therapy platform
‘Digital therapist’ Woebot perks up with $90M for AI-powered mental health platform (FierceBiotech): In news sure to excite even the most melancholy of artificial intelligence-powered chatbots, mental health platform Woebot has closed its series B funding round with a whopping $90 million. The funds will go toward building out Woebot’s AI technology and digital therapeutics, as well as the teams responsible for the development and commercialization of the platform. Woebot’s technology centers around the eponymous “digital therapist,” which uses conversational AI software to form therapeu...
Source: SharpBrains - July 26, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Peak Performance Technology & Innovation artificial intelligence chatbot cognitive behavior therapy dialectical behavior therapy digital self-therapy digital therapeutics interpersonal psychotherapy mental health c Source Type: blogs

Helping young brains fight off anxiety by training and raising cognitive control
This article was originally published by AIM Youth Mental Health, a non-profit dedicated to finding and funding promising youth mental health research that can identify solutions to make a difference in young people’s lives today, which contributed to funding Kate Fitzgerald’s research. Related articles: What are cognitive abilities and how to boost them? Can brain training work? Yes, if it meets these 5 conditions New book on how to practice mindfulness meditation with humor and playfulness Six tips to build resilience and prevent brain-damaging stress The post Helping young brains fight off anxiety by ...
Source: SharpBrains - July 23, 2021 Category: Neuroscience Authors: Greater Good Science Center Tags: Education & Lifelong Learning anxiety brain markers brain training childhood cognitive-behavioral-therapy cognitive-capacities cognitive-control cognitive-skills Cognitive-Training frontal-lobes Kate Fitzgerald Kid Power program Source Type: blogs

Study finds that cognitive activity in old age may delay the onset of dementia by 5 years
Conclusion: A cognitively active lifestyle in old age may delay the onset of dementia in AD by as much as 5 years. The Study in Context: Build Your Cognitive Reserve: An Interview with Dr. Yaakov Stern New studies reinforce Education and Cognitive Reserve –instead of drugs targeting beta amyloid– as most promising avenue to prolong cognitive health and reduce dementia risk The post Study finds that cognitive activity in old age may delay the onset of dementia by 5 years appeared first on SharpBrains. (Source: SharpBrains)
Source: SharpBrains - July 20, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Education & Lifelong Learning activities Alzheimers brain changes cognitive activity cognitive-reserve cognitively stimulating cognitively stimulating activities dementia dementia onset lifestyle neuropathologi Source Type: blogs

UK report identifies opportunities and gaps for digital tech to improve, not harm, mental health
We describe the technologies contributing to the solutions as well as specific implementations, and the benefits they bring to citizens and the mental health care workforce. There are major opportunities in adult social care for the improvement of care using technology, from both a workforce and citizen perspective. Mental healthcare sits between health and care and there are substantial opportunities to deploy technology to improve mental health … Targeted support and intervention is needed to grow the sector to provide an adequate range of companies to suit the needs of individuals, care is not one size fits all a...
Source: SharpBrains - July 19, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation Future Care Capital government improve mental health mental health services Mental Health Tech Source Type: blogs

Promote brain plasticity and keep your mind at ease by taking your daily “exercise pill”
This article was originally published on The Conversation. News in Context: Can you grow your hippocampus? Yes. Here’s how, and why it matters To harness neuroplasticity, start with enthusiasm Three ways to protect your mental health during –and after– COVID-19 Exploring the human brain and how it responds to stress (1/3) The post Promote brain plasticity and keep your mind at ease by taking your daily “exercise pill” appeared first on SharpBrains. (Source: SharpBrains)
Source: SharpBrains - July 14, 2021 Category: Neuroscience Authors: The Conversation Tags: Brain/ Mental Health Education & Lifelong Learning anxiety BDNF brain-cells Brain-Plasticity cognitive-performance exercise exercise pill hippocampus memory function neurobiology Neurons neuroplasticity neuroscientist neurotr Source Type: blogs

Becoming better mind-wanderers to boost problem-solving and mood
In this study, researchers used electroencephalogram technology to see what happens in our brains when we are engaged in different types of mind-wandering. To do that, they had people perform a mundane, repetitive task and interrupted them occasionally to see what they were thinking about, while continuously monitoring their brain activity. Some participants reported thoughts that Kam calls “constrained,” involving things like ruminating over a fight with a spouse or thinking about how to manage a work problem. While these thoughts were not related to the task at hand, they were still somewhat focused. Others r...
Source: SharpBrains - July 12, 2021 Category: Neuroscience Authors: Greater Good Science Center Tags: Education & Lifelong Learning brain-activity cognitive cognitive-abilities cognitive-skills creativity daydreaming electroencephalogram mind-wandering nature neural marker problem-solving productivity Source Type: blogs

Study shows promising results of EEG-based brain training in helping adults with ADHD
Conclusions: A single-session of alpha down-regulation NFB was able to reverse the abnormal neurocognitive signatures of adult ADHD during a Go/NoGo task. Significance: The study demonstrates for the first time the beneficial neurobehavioral effect of a single NFB session in adult ADHD, and reinforces the notion that ERPs could serve as useful diagnostic/prognostic markers of executive dysfunction. The Study in Context: Meta-analysis finds sustained benefits of neurofeedback for kids with ADHD What are cognitive abilities and how to boost them? Study shows why children with ADHD should be reevaluated each year: Atte...
Source: SharpBrains - July 8, 2021 Category: Neuroscience Authors: SharpBrains Tags: Attention & ADD/ADHD Brain/ Mental Health Peak Performance Technology & Innovation adulthood attention deficit hyperactivity disorder brain training brain training for adhd clinical clinical neurophysiology EEG electroencephalogram Source Type: blogs

The neuroscience behind why our brains will need time to adjust to ‘un-social distancing’
This article was originally published on The Conversation. News in Context: Can you grow your hippocampus? Yes. Here’s how, and why it matters Three ways to protect your mental health during –and after– COVID-19 Exploring the human brain and how it responds to stress (1/3) Brain teaser: What do you see first, people or other animals? Three quick brain teaser games to test your perceptual and cognitive skills The post The neuroscience behind why our brains will need time to adjust to ‘un-social distancing’ appeared first on SharpBrains. (Source: SharpBrains)
Source: SharpBrains - July 6, 2021 Category: Neuroscience Authors: The Conversation Tags: Education & Lifelong Learning anxiety brain-teaser cognitive-function cognitive-skills COVID-19 hippocampus mental health neuroscience social distancing social homeostasis social memory Stress Source Type: blogs

Systematic review calls for early targeted interventions to help babies and toddlers with cerebral palsy harness time window with maximum brain plasticity
Early targeted intervention ‘critical’ for improving outcomes in cerebral palsy (Healio): Early intervention for children with or at high risk for cerebral palsy should begin “as soon as possible” in order to build on “a critical developmental time,” according to results of a systematic review published in JAMA Pediatrics. Researchers conducted the review to develop clinical guidelines for early intervention among children at high risk for cerebral palsy (CP) and their families … the researchers searched six databases for “the best available evidence” regarding early i...
Source: SharpBrains - July 2, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Education & Lifelong Learning Attention-Deficit autism spectrum disorder Brain-Plasticity Cerebral palsy cognitive-skills disabilities early intervention intellectual disability language impairment Neurodevelopm Source Type: blogs

Update on the aducanumab (Aduhelm) saga, retirement, financial advice, cognitive health, excessive worrying, neurotech, and more
Welcome to a new edition of SharpBrains’ e‑newsletter, providing this time a summary of the saga around the FDA approval of aducanumab (Aduhelm) as a supposed treatment for Alzheimer’s Disease, plus a range of timely research findings and resources for lifelong brain health. First, below are some key reads to navigate “probably the worst drug approval decision in recent U.S. history” — Dr. Aaron Kesselheim, the Professor of Medicine at Harvard Medical School who resigned rom the FDA Advisory Committee in protest. #1. Growing backlash against the FDA approval of unpro...
Source: SharpBrains - June 30, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Education & Lifelong Learning SharpBrains Monthly eNewsletter Technology & Innovation aducanumab Aduhelm Alzheimers-disease anti-amyloid drug Biogen Brain Teasers brain-teaser cognitive decline cognitive-exerci Source Type: blogs

The explosion of mental health apps raises substantial opportunities –and tough questions
In the eyes of the tech industry, mental health treatment is an area ripe for disruption. In any given year, 1 in 5 adults in the U.S. experience a form of mental illness, according to federal estimates. And research indicates only about half of them receive treatment in a system that is understaffed and ill distributed to meet demand. For tech startups looking to cash in on unmet need, that translates into more than 50 million potential customers. Venture capital firms invested more than $2.4 billion in digital behavioral health apps in 2020 — more than twice the amount invested in 2019 — touting support or tr...
Source: SharpBrains - June 28, 2021 Category: Neuroscience Authors: Kaiser Health News Tags: Brain/ Mental Health Technology & Innovation anxiety BetterHelp brain-illness Brightside cerebral depression digital behavioral health FDA Food and Drug Administration Ginger health apps mental illness mental-health-treatment Source Type: blogs

Health payers –including Medicare and Point32Health–to question Aduhelm pricing and its “reasonable and necessary” use
State’s Second-Largest Health Insurer Slams Biogen For Costly Alzheimer’s Drug (The Boston Globe): The state’s second-biggest health insurer is threatening to limit or not cover Biogen’s new Alzheimer’s drug, accusing the Cambridge biotech of putting “excessive corporate profits” ahead of patients by charging $56,000 a year for the controversial treatment. Michael Sherman, chief medical officer for Point32Health, the insurance company formed by the recent merger of Tufts Health Plan and Harvard Pilgrim Health Care, said Biogen should cut the cost of the drug called Aduhelm by a fac...
Source: SharpBrains - June 24, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Aduhelm Alzheimer's drug amyloid PET scans Biogen Centers for Medicare and Medicaid Services clinical efficacy Point32Health Source Type: blogs

Prescription software firm Pear Therapeutics to go public via $1.6 billion SPAC deal, harnessing 3 FDA-authorized products and 14 candidates
Pear Therapeutics to Go Public in Roughly $1.6 Billion SPAC Deal (The Wall Street Journal): Medical technology company Pear Therapeutics Inc. has agreed to go public by merging with a blank-check company with ties to the Pritzker Vlock Family Office, betting on the growing role of prescription digital therapeutics. The proposed merger would give the combined company a pro forma equity value of about $1.6 billion. Boston-based Pear Therapeutics is merging with Thimble Point Acquisition Corp. in a deal that’s expected to close in the second half of the year, subject to Thimble Point shareholder approval. Investors that...
Source: SharpBrains - June 23, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation digital therapeutics FDA Food and Drug Administration Neuberger Berman Group patient retention PEAR Pear Holdings Corp Pear Therapeutics prescription digital therapeutics prescription soft Source Type: blogs

Can the controversial FDA approval of Aduhelm backfire and delay the discovery of actual Alzheimer ’s treatments? (Yes, it can)
This article was originally published on The Conversation. News in Context: US Senator Joe Manchin calls for a new FDA Commissioner to replace current (acting) one who “has repeatedly ignored public health concerns and shown a dereliction of duty” over opioids and aducanumab First, do no harm? Six reasons to approach anti-amyloid drug Aduhelm cautiously, if at all Growing backlash against the FDA approval of unproven Alzheimer’s treatment Aduhelm, by Biogen A critical appraisal of amyloid-B-targeting therapies for Alzheimer disease   The post Can the controversial FDA approval of Aduhelm ...
Source: SharpBrains - June 21, 2021 Category: Neuroscience Authors: The Conversation Tags: Brain/ Mental Health aducanumab Aduhelm Alzheimer's biomarkers Alzheimer's drug Alzheimers-disease amyloid Biogen clinical-trials FDA FDA drug approval process tau Source Type: blogs

US Senator Joe Manchin calls for a new FDA Commissioner to replace current (acting) one who “has repeatedly ignored public health concerns and shown a dereliction of duty” over opioids and aducanumab
Key Democrat Manchin Bashes FDA Leader on Alzheimer’s Approval (Bloomberg): Senator Joe Manchin, a moderate Democrat considered a crucial vote within the party’s slim Senate majority, said Janet Woodcock, the temporary head of the Food and Drug Administration, should be quickly replaced with a permanent leader. Manchin blasted an FDA decision to approve the controversial Alzheimer’s therapy Aduhelm despite conflicting evidence that the Biogen Inc. drug works and an overwhelmingly negative vote against the therapy by agency advisers. The FDA ruling led three members of that panel to quit in protest…...
Source: SharpBrains - June 18, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health aducanumab Aduhelm Alzheimer's treatments Alzheimer’s therapy Alzheimers-disease Biogen FDA Food and Drug Administration Joe Manchin opioids OxyContin public-health Source Type: blogs

Ten days left to submit proposals to the Wellcome Trust for Workplace Mental Health 2021
Dear Colleagues, Wellcome are delighted to announce the launch of our Workplace Mental Health 2021 Request for Proposals. Businesses all over the world are increasingly thinking about how they can most effectively support the mental health of their staff, even more so in light of the Covid-19 pandemic. However, despite growing interest and investment in workplace mental health, we still have so much to learn about what works. In 2020, we asked ten global research teams to review the evidence behind a sample of promising approaches for preventing anxiety and depression in the workplace, focusing on younger workers. The rese...
Source: SharpBrains - June 17, 2021 Category: Neuroscience Authors: Wellcome Trust Tags: Brain/ Mental Health Peak Performance preventing anxiety preventing depression Wellcome Trust workplace workplace mental health Source Type: blogs

First, do no harm? Six reasons to approach anti-amyloid drug Aduhelm cautiously, if at all
6 ways the FDA’s approval of Aduhelm does more harm than good (STAT News): Like many people, I was shocked when the Food and Drug Administration ignored the advice of its neurological drugs advisory panel and broadly approved Biogen’s new drug, Aduhelm, even for populations never included in the clinical trials to assess the drug. I am not a casual bystander to this controversial decision. I am a physician who has been treating people with Alzheimer’s since 1982; an early researcher into the biology of amyloid, the brain protein that Aduhelm targets; someone with a strong personal family history of dement...
Source: SharpBrains - June 16, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Aduhelm amyloid anti-amyloid dementia FDA Food and Drug Administration neurological drugs Source Type: blogs

Growing backlash against the FDA approval of unproven Alzheimer ’s treatment Aduhelm, by Biogen
ICER Issues Statement on the FDA’s Approval of Aducanumab for Alzheimer’s Disease (Institute for Clinical and Economic Review): The Institute for Clinical and Economic Review (ICER) believes that the FDA, in approving aducanumab (Aduhelm™, Biogen) for the treatment of Alzheimer’s disease, has failed in its responsibility to protect patients and families from unproven treatments with known harms. Our review of the evidence was concordant with that of many independent experts: current evidence is insufficient to demonstrate that aducanumab benefits patients. The avenue forward has seemed clear: anothe...
Source: SharpBrains - June 14, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health aducanumab Aduhelm Alzheimer’s Disease Alzheimer’s disease treatment amyloid amyloid plaques amyloid-related imaging abnormalities ARIA Biogen brain swelling clinical benefit FDA ICER Janet Woodcock N Source Type: blogs

Study in China finds that retirement may accelerate cognitive decline, even for those with stable income
This article was originally published on The Conversation. The Study: Pension Benefits, Early Retirement and Human Capital Depreciation in Late Adulthood (Papers, arXiv.org) Abstract: Historically, economists have mainly focused on human capital accumulation and considerably less so on the causes and consequences of human capital depreciation in late adulthood. Studying human capital depreciation over the life cycle has powerful economic consequences for decision-making in old age. Using data from the introduction of a retirement program in China, we examine how the introduction of a retirement program influences ind...
Source: SharpBrains - June 10, 2021 Category: Neuroscience Authors: The Conversation Tags: Brain/ Mental Health Education & Lifelong Learning aging China cognition cognitive decline cognitive-abilities cognitive-functioning cognitive-skills dementia developing countries mental retirement middle-income countries neuropl Source Type: blogs

DARPA-funded nonsurgical neurotechnologies push the frontier of brain-machine interfaces
This article will first overview the DARPA program and the basics of these three programs. Then, a look at the common electronics technologies that are being used in biotechnology at Rice University. Keep reading excellent article HERE, over at All About Circuits. About DARPA’s N3 program: Six paths to the nonsurgical future of brain-machine interfaces (DARPA): Back in 2019, DARPA awarded funding to six organizations to support the Next-Generation Nonsurgical Neurotechnology (N3) program, first announced in March 2018. Battelle Memorial Institute, Carnegie Mellon University, Johns Hopkins University Applied Phys...
Source: SharpBrains - June 9, 2021 Category: Neuroscience Authors: SharpBrains Tags: Peak Performance Technology & Innovation BCI brain brain-to-brain communication cognitive-skills DARPA human-machine interfacing neural-activity neuroplasticity Next-Generation Nonsurgical Neurotechnology noninvasive neurotechnologie Source Type: blogs

Debate: What is the role of financial advisors and platforms in detecting and addressing cognitive decline among older clients?
Baby Boomers’ Biggest Financial Risk: Cognitive Decline (The Wall Street Journal): For baby boomers who manage their own nest eggs, a risk is looming that has nothing to do with stock prices or interest rates. The risk is cognitive decline, which can rob them of their judgment, often without much warning. One big mistake—or a series of smaller ones—can go unnoticed by loved ones, and potentially ravage a lifetime of hard-earned savings. To mitigate these risks, there are things baby boomers and others can do now to prepare for any problems. In addition, big do-it-yourself investing and trading venues like...
Source: SharpBrains - June 7, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Education & Lifelong Learning baby-boomers Charles Schwab cognitive Cognitive Aging cognitive decline Cognitive-impairment Fidelity Investments Money retirement Vanguard Group Source Type: blogs

Brain teasers en espa ñol: ¿cuál es el número que falta en el cuarto triángulo?
(Same brain teaser in English here) Es viernes y quizás algunos necesitemos un pequeño empujón cognitivo para abordar el fin de semana… Aquí va un breve desafío matemático: ¿Qué número que falta en el cuarto triángulo? Aviso a tod@s esos sharp brains: Sí, puede haber más de una respuesta … pero asegúrate de que tu solución funciona bien en todos los triángulos! _______________ Solución El número de arriba menos el número de abajo a la izquierda, multiplicado por el número de ...
Source: SharpBrains - June 4, 2021 Category: Neuroscience Authors: Caroline Latham Tags: Brain Teasers En Español acertijos brain teaser for adults brain teasers for kids brain teasers for teens brain-teaser cognitivo desafío matemático ejercicio cognitivo triángulo Source Type: blogs

Don ’t worry, be happy: How excessive worrying may influence the rate of neurodegeneration
Worrying and the Aging Brain (Dana Foundation): Over the past decade, scientists and clinicians have noted a significant association between common mental health conditions and accelerated brain aging—the changes to brain structure, physiology, and function that are thought to lead to later cognitive decline. Both depression and anxiety disorders, for example, are strongly correlated with the development of dementias including Alzheimer’s disease later in life, yet it has been unclear why. Neuroscientists and gerontologists around the globe have diligently worked to investigate which particular symptoms might c...
Source: SharpBrains - June 3, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health anxiety anxiety-disorders brain-age brain-aging brain-structure cognitive decline dementia depression neurodegeneration worry Source Type: blogs

Eye-tracking pioneer Smart Eye acquires MIT spin-off Affectiva to augment driver monitoring systems and more
Emotion-detection software start-up Affectiva acquired for $73.5M (TechCrunch): Smart Eye, the publicly traded Swedish company that supplies driver monitoring systems for a dozen automakers, has acquired emotion-detection software startup Affectiva for $73.5 million in a cash-and-stock deal. Affectiva, which spun out of the MIT Media Lab in 2009, has developed software that can detect and understand human emotion, which Smart Eye is keen to combine with its own AI-based eye-tracking technology. The companies’ founders see an opportunity to expand beyond driver monitoring systems — tech that is often used in con...
Source: SharpBrains - June 1, 2021 Category: Neuroscience Authors: SharpBrains Tags: Peak Performance Technology & Innovation Affectiva driver monitoring emotional state eye-tracking Human-Factors interior sensing MIT MIT-Media-Lab neurotechnologies Neurotechnology Smart Eye Source Type: blogs

On building better brains at any age, treating Depression vs. Dementia, emerging neurotechnologies, psychedelics, and more
Welcome to a new edition of SharpBrains’ e‑newsletter, featuring eleven new research findings and innovative resources for lifelong cognitive and brain health. #1. Debate: Are depression and dementia two sides of the same coin? And, if they are, how to best approach treatment? #2. Either way, the earlier the better, but it’s never too late: New book outlines the five lifestyle pillars to “build a better brain at any age” #3. “If I were a cardiologist evaluating a patient’s chest pain, for instance, I would speak with the patient, but then I would listen to their heart and measure ...
Source: SharpBrains - May 28, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Education & Lifelong Learning Technology & Innovation brain health cognitive cognitive healthcare cognitive--disorders cognitive-health Cumulus Neuroscience dementia depression neurotechnologies psychedelics Source Type: blogs