Study finds that cognitive activity in old age may delay the onset of dementia by 5 years
Conclusion: A cognitively active lifestyle in old age may delay the onset of dementia in AD by as much as 5 years. The Study in Context: Build Your Cognitive Reserve: An Interview with Dr. Yaakov Stern New studies reinforce Education and Cognitive Reserve –instead of drugs targeting beta amyloid– as most promising avenue to prolong cognitive health and reduce dementia risk The post Study finds that cognitive activity in old age may delay the onset of dementia by 5 years appeared first on SharpBrains. (Source: SharpBrains)
Source: SharpBrains - July 20, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Education & Lifelong Learning activities Alzheimers brain changes cognitive activity cognitive-reserve cognitively stimulating cognitively stimulating activities dementia dementia onset lifestyle neuropathologi Source Type: blogs

UK report identifies opportunities and gaps for digital tech to improve, not harm, mental health
We describe the technologies contributing to the solutions as well as specific implementations, and the benefits they bring to citizens and the mental health care workforce. There are major opportunities in adult social care for the improvement of care using technology, from both a workforce and citizen perspective. Mental healthcare sits between health and care and there are substantial opportunities to deploy technology to improve mental health … Targeted support and intervention is needed to grow the sector to provide an adequate range of companies to suit the needs of individuals, care is not one size fits all a...
Source: SharpBrains - July 19, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation Future Care Capital government improve mental health mental health services Mental Health Tech Source Type: blogs

Promote brain plasticity and keep your mind at ease by taking your daily “exercise pill”
This article was originally published on The Conversation. News in Context: Can you grow your hippocampus? Yes. Here’s how, and why it matters To harness neuroplasticity, start with enthusiasm Three ways to protect your mental health during –and after– COVID-19 Exploring the human brain and how it responds to stress (1/3) The post Promote brain plasticity and keep your mind at ease by taking your daily “exercise pill” appeared first on SharpBrains. (Source: SharpBrains)
Source: SharpBrains - July 14, 2021 Category: Neuroscience Authors: The Conversation Tags: Brain/ Mental Health Education & Lifelong Learning anxiety BDNF brain-cells Brain-Plasticity cognitive-performance exercise exercise pill hippocampus memory function neurobiology Neurons neuroplasticity neuroscientist neurotr Source Type: blogs

Becoming better mind-wanderers to boost problem-solving and mood
In this study, researchers used electroencephalogram technology to see what happens in our brains when we are engaged in different types of mind-wandering. To do that, they had people perform a mundane, repetitive task and interrupted them occasionally to see what they were thinking about, while continuously monitoring their brain activity. Some participants reported thoughts that Kam calls “constrained,” involving things like ruminating over a fight with a spouse or thinking about how to manage a work problem. While these thoughts were not related to the task at hand, they were still somewhat focused. Others r...
Source: SharpBrains - July 12, 2021 Category: Neuroscience Authors: Greater Good Science Center Tags: Education & Lifelong Learning brain-activity cognitive cognitive-abilities cognitive-skills creativity daydreaming electroencephalogram mind-wandering nature neural marker problem-solving productivity Source Type: blogs

Study shows promising results of EEG-based brain training in helping adults with ADHD
Conclusions: A single-session of alpha down-regulation NFB was able to reverse the abnormal neurocognitive signatures of adult ADHD during a Go/NoGo task. Significance: The study demonstrates for the first time the beneficial neurobehavioral effect of a single NFB session in adult ADHD, and reinforces the notion that ERPs could serve as useful diagnostic/prognostic markers of executive dysfunction. The Study in Context: Meta-analysis finds sustained benefits of neurofeedback for kids with ADHD What are cognitive abilities and how to boost them? Study shows why children with ADHD should be reevaluated each year: Atte...
Source: SharpBrains - July 8, 2021 Category: Neuroscience Authors: SharpBrains Tags: Attention & ADD/ADHD Brain/ Mental Health Peak Performance Technology & Innovation adulthood attention deficit hyperactivity disorder brain training brain training for adhd clinical clinical neurophysiology EEG electroencephalogram Source Type: blogs

The neuroscience behind why our brains will need time to adjust to ‘un-social distancing’
This article was originally published on The Conversation. News in Context: Can you grow your hippocampus? Yes. Here’s how, and why it matters Three ways to protect your mental health during –and after– COVID-19 Exploring the human brain and how it responds to stress (1/3) Brain teaser: What do you see first, people or other animals? Three quick brain teaser games to test your perceptual and cognitive skills The post The neuroscience behind why our brains will need time to adjust to ‘un-social distancing’ appeared first on SharpBrains. (Source: SharpBrains)
Source: SharpBrains - July 6, 2021 Category: Neuroscience Authors: The Conversation Tags: Education & Lifelong Learning anxiety brain-teaser cognitive-function cognitive-skills COVID-19 hippocampus mental health neuroscience social distancing social homeostasis social memory Stress Source Type: blogs

Systematic review calls for early targeted interventions to help babies and toddlers with cerebral palsy harness time window with maximum brain plasticity
Early targeted intervention ‘critical’ for improving outcomes in cerebral palsy (Healio): Early intervention for children with or at high risk for cerebral palsy should begin “as soon as possible” in order to build on “a critical developmental time,” according to results of a systematic review published in JAMA Pediatrics. Researchers conducted the review to develop clinical guidelines for early intervention among children at high risk for cerebral palsy (CP) and their families … the researchers searched six databases for “the best available evidence” regarding early i...
Source: SharpBrains - July 2, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Education & Lifelong Learning Attention-Deficit autism spectrum disorder Brain-Plasticity Cerebral palsy cognitive-skills disabilities early intervention intellectual disability language impairment Neurodevelopm Source Type: blogs

Update on the aducanumab (Aduhelm) saga, retirement, financial advice, cognitive health, excessive worrying, neurotech, and more
Welcome to a new edition of SharpBrains’ e‑newsletter, providing this time a summary of the saga around the FDA approval of aducanumab (Aduhelm) as a supposed treatment for Alzheimer’s Disease, plus a range of timely research findings and resources for lifelong brain health. First, below are some key reads to navigate “probably the worst drug approval decision in recent U.S. history” — Dr. Aaron Kesselheim, the Professor of Medicine at Harvard Medical School who resigned rom the FDA Advisory Committee in protest. #1. Growing backlash against the FDA approval of unpro...
Source: SharpBrains - June 30, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Education & Lifelong Learning SharpBrains Monthly eNewsletter Technology & Innovation aducanumab Aduhelm Alzheimers-disease anti-amyloid drug Biogen Brain Teasers brain-teaser cognitive decline cognitive-exerci Source Type: blogs

The explosion of mental health apps raises substantial opportunities –and tough questions
In the eyes of the tech industry, mental health treatment is an area ripe for disruption. In any given year, 1 in 5 adults in the U.S. experience a form of mental illness, according to federal estimates. And research indicates only about half of them receive treatment in a system that is understaffed and ill distributed to meet demand. For tech startups looking to cash in on unmet need, that translates into more than 50 million potential customers. Venture capital firms invested more than $2.4 billion in digital behavioral health apps in 2020 — more than twice the amount invested in 2019 — touting support or tr...
Source: SharpBrains - June 28, 2021 Category: Neuroscience Authors: Kaiser Health News Tags: Brain/ Mental Health Technology & Innovation anxiety BetterHelp brain-illness Brightside cerebral depression digital behavioral health FDA Food and Drug Administration Ginger health apps mental illness mental-health-treatment Source Type: blogs

Health payers –including Medicare and Point32Health–to question Aduhelm pricing and its “reasonable and necessary” use
State’s Second-Largest Health Insurer Slams Biogen For Costly Alzheimer’s Drug (The Boston Globe): The state’s second-biggest health insurer is threatening to limit or not cover Biogen’s new Alzheimer’s drug, accusing the Cambridge biotech of putting “excessive corporate profits” ahead of patients by charging $56,000 a year for the controversial treatment. Michael Sherman, chief medical officer for Point32Health, the insurance company formed by the recent merger of Tufts Health Plan and Harvard Pilgrim Health Care, said Biogen should cut the cost of the drug called Aduhelm by a fac...
Source: SharpBrains - June 24, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Aduhelm Alzheimer's drug amyloid PET scans Biogen Centers for Medicare and Medicaid Services clinical efficacy Point32Health Source Type: blogs

Prescription software firm Pear Therapeutics to go public via $1.6 billion SPAC deal, harnessing 3 FDA-authorized products and 14 candidates
Pear Therapeutics to Go Public in Roughly $1.6 Billion SPAC Deal (The Wall Street Journal): Medical technology company Pear Therapeutics Inc. has agreed to go public by merging with a blank-check company with ties to the Pritzker Vlock Family Office, betting on the growing role of prescription digital therapeutics. The proposed merger would give the combined company a pro forma equity value of about $1.6 billion. Boston-based Pear Therapeutics is merging with Thimble Point Acquisition Corp. in a deal that’s expected to close in the second half of the year, subject to Thimble Point shareholder approval. Investors that...
Source: SharpBrains - June 23, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation digital therapeutics FDA Food and Drug Administration Neuberger Berman Group patient retention PEAR Pear Holdings Corp Pear Therapeutics prescription digital therapeutics prescription soft Source Type: blogs

Can the controversial FDA approval of Aduhelm backfire and delay the discovery of actual Alzheimer ’s treatments? (Yes, it can)
This article was originally published on The Conversation. News in Context: US Senator Joe Manchin calls for a new FDA Commissioner to replace current (acting) one who “has repeatedly ignored public health concerns and shown a dereliction of duty” over opioids and aducanumab First, do no harm? Six reasons to approach anti-amyloid drug Aduhelm cautiously, if at all Growing backlash against the FDA approval of unproven Alzheimer’s treatment Aduhelm, by Biogen A critical appraisal of amyloid-B-targeting therapies for Alzheimer disease   The post Can the controversial FDA approval of Aduhelm ...
Source: SharpBrains - June 21, 2021 Category: Neuroscience Authors: The Conversation Tags: Brain/ Mental Health aducanumab Aduhelm Alzheimer's biomarkers Alzheimer's drug Alzheimers-disease amyloid Biogen clinical-trials FDA FDA drug approval process tau Source Type: blogs

US Senator Joe Manchin calls for a new FDA Commissioner to replace current (acting) one who “has repeatedly ignored public health concerns and shown a dereliction of duty” over opioids and aducanumab
Key Democrat Manchin Bashes FDA Leader on Alzheimer’s Approval (Bloomberg): Senator Joe Manchin, a moderate Democrat considered a crucial vote within the party’s slim Senate majority, said Janet Woodcock, the temporary head of the Food and Drug Administration, should be quickly replaced with a permanent leader. Manchin blasted an FDA decision to approve the controversial Alzheimer’s therapy Aduhelm despite conflicting evidence that the Biogen Inc. drug works and an overwhelmingly negative vote against the therapy by agency advisers. The FDA ruling led three members of that panel to quit in protest…...
Source: SharpBrains - June 18, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health aducanumab Aduhelm Alzheimer's treatments Alzheimer’s therapy Alzheimers-disease Biogen FDA Food and Drug Administration Joe Manchin opioids OxyContin public-health Source Type: blogs

Ten days left to submit proposals to the Wellcome Trust for Workplace Mental Health 2021
Dear Colleagues, Wellcome are delighted to announce the launch of our Workplace Mental Health 2021 Request for Proposals. Businesses all over the world are increasingly thinking about how they can most effectively support the mental health of their staff, even more so in light of the Covid-19 pandemic. However, despite growing interest and investment in workplace mental health, we still have so much to learn about what works. In 2020, we asked ten global research teams to review the evidence behind a sample of promising approaches for preventing anxiety and depression in the workplace, focusing on younger workers. The rese...
Source: SharpBrains - June 17, 2021 Category: Neuroscience Authors: Wellcome Trust Tags: Brain/ Mental Health Peak Performance preventing anxiety preventing depression Wellcome Trust workplace workplace mental health Source Type: blogs

First, do no harm? Six reasons to approach anti-amyloid drug Aduhelm cautiously, if at all
6 ways the FDA’s approval of Aduhelm does more harm than good (STAT News): Like many people, I was shocked when the Food and Drug Administration ignored the advice of its neurological drugs advisory panel and broadly approved Biogen’s new drug, Aduhelm, even for populations never included in the clinical trials to assess the drug. I am not a casual bystander to this controversial decision. I am a physician who has been treating people with Alzheimer’s since 1982; an early researcher into the biology of amyloid, the brain protein that Aduhelm targets; someone with a strong personal family history of dement...
Source: SharpBrains - June 16, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Aduhelm amyloid anti-amyloid dementia FDA Food and Drug Administration neurological drugs Source Type: blogs

Growing backlash against the FDA approval of unproven Alzheimer ’s treatment Aduhelm, by Biogen
ICER Issues Statement on the FDA’s Approval of Aducanumab for Alzheimer’s Disease (Institute for Clinical and Economic Review): The Institute for Clinical and Economic Review (ICER) believes that the FDA, in approving aducanumab (Aduhelm™, Biogen) for the treatment of Alzheimer’s disease, has failed in its responsibility to protect patients and families from unproven treatments with known harms. Our review of the evidence was concordant with that of many independent experts: current evidence is insufficient to demonstrate that aducanumab benefits patients. The avenue forward has seemed clear: anothe...
Source: SharpBrains - June 14, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health aducanumab Aduhelm Alzheimer’s Disease Alzheimer’s disease treatment amyloid amyloid plaques amyloid-related imaging abnormalities ARIA Biogen brain swelling clinical benefit FDA ICER Janet Woodcock N Source Type: blogs

Study in China finds that retirement may accelerate cognitive decline, even for those with stable income
This article was originally published on The Conversation. The Study: Pension Benefits, Early Retirement and Human Capital Depreciation in Late Adulthood (Papers, arXiv.org) Abstract: Historically, economists have mainly focused on human capital accumulation and considerably less so on the causes and consequences of human capital depreciation in late adulthood. Studying human capital depreciation over the life cycle has powerful economic consequences for decision-making in old age. Using data from the introduction of a retirement program in China, we examine how the introduction of a retirement program influences ind...
Source: SharpBrains - June 10, 2021 Category: Neuroscience Authors: The Conversation Tags: Brain/ Mental Health Education & Lifelong Learning aging China cognition cognitive decline cognitive-abilities cognitive-functioning cognitive-skills dementia developing countries mental retirement middle-income countries neuropl Source Type: blogs

DARPA-funded nonsurgical neurotechnologies push the frontier of brain-machine interfaces
This article will first overview the DARPA program and the basics of these three programs. Then, a look at the common electronics technologies that are being used in biotechnology at Rice University. Keep reading excellent article HERE, over at All About Circuits. About DARPA’s N3 program: Six paths to the nonsurgical future of brain-machine interfaces (DARPA): Back in 2019, DARPA awarded funding to six organizations to support the Next-Generation Nonsurgical Neurotechnology (N3) program, first announced in March 2018. Battelle Memorial Institute, Carnegie Mellon University, Johns Hopkins University Applied Phys...
Source: SharpBrains - June 9, 2021 Category: Neuroscience Authors: SharpBrains Tags: Peak Performance Technology & Innovation BCI brain brain-to-brain communication cognitive-skills DARPA human-machine interfacing neural-activity neuroplasticity Next-Generation Nonsurgical Neurotechnology noninvasive neurotechnologie Source Type: blogs

Debate: What is the role of financial advisors and platforms in detecting and addressing cognitive decline among older clients?
Baby Boomers’ Biggest Financial Risk: Cognitive Decline (The Wall Street Journal): For baby boomers who manage their own nest eggs, a risk is looming that has nothing to do with stock prices or interest rates. The risk is cognitive decline, which can rob them of their judgment, often without much warning. One big mistake—or a series of smaller ones—can go unnoticed by loved ones, and potentially ravage a lifetime of hard-earned savings. To mitigate these risks, there are things baby boomers and others can do now to prepare for any problems. In addition, big do-it-yourself investing and trading venues like...
Source: SharpBrains - June 7, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Education & Lifelong Learning baby-boomers Charles Schwab cognitive Cognitive Aging cognitive decline Cognitive-impairment Fidelity Investments Money retirement Vanguard Group Source Type: blogs

Brain teasers en espa ñol: ¿cuál es el número que falta en el cuarto triángulo?
(Same brain teaser in English here) Es viernes y quizás algunos necesitemos un pequeño empujón cognitivo para abordar el fin de semana… Aquí va un breve desafío matemático: ¿Qué número que falta en el cuarto triángulo? Aviso a tod@s esos sharp brains: Sí, puede haber más de una respuesta … pero asegúrate de que tu solución funciona bien en todos los triángulos! _______________ Solución El número de arriba menos el número de abajo a la izquierda, multiplicado por el número de ...
Source: SharpBrains - June 4, 2021 Category: Neuroscience Authors: Caroline Latham Tags: Brain Teasers En Español acertijos brain teaser for adults brain teasers for kids brain teasers for teens brain-teaser cognitivo desafío matemático ejercicio cognitivo triángulo Source Type: blogs

Don ’t worry, be happy: How excessive worrying may influence the rate of neurodegeneration
Worrying and the Aging Brain (Dana Foundation): Over the past decade, scientists and clinicians have noted a significant association between common mental health conditions and accelerated brain aging—the changes to brain structure, physiology, and function that are thought to lead to later cognitive decline. Both depression and anxiety disorders, for example, are strongly correlated with the development of dementias including Alzheimer’s disease later in life, yet it has been unclear why. Neuroscientists and gerontologists around the globe have diligently worked to investigate which particular symptoms might c...
Source: SharpBrains - June 3, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health anxiety anxiety-disorders brain-age brain-aging brain-structure cognitive decline dementia depression neurodegeneration worry Source Type: blogs

Eye-tracking pioneer Smart Eye acquires MIT spin-off Affectiva to augment driver monitoring systems and more
Emotion-detection software start-up Affectiva acquired for $73.5M (TechCrunch): Smart Eye, the publicly traded Swedish company that supplies driver monitoring systems for a dozen automakers, has acquired emotion-detection software startup Affectiva for $73.5 million in a cash-and-stock deal. Affectiva, which spun out of the MIT Media Lab in 2009, has developed software that can detect and understand human emotion, which Smart Eye is keen to combine with its own AI-based eye-tracking technology. The companies’ founders see an opportunity to expand beyond driver monitoring systems — tech that is often used in con...
Source: SharpBrains - June 1, 2021 Category: Neuroscience Authors: SharpBrains Tags: Peak Performance Technology & Innovation Affectiva driver monitoring emotional state eye-tracking Human-Factors interior sensing MIT MIT-Media-Lab neurotechnologies Neurotechnology Smart Eye Source Type: blogs

On building better brains at any age, treating Depression vs. Dementia, emerging neurotechnologies, psychedelics, and more
Welcome to a new edition of SharpBrains’ e‑newsletter, featuring eleven new research findings and innovative resources for lifelong cognitive and brain health. #1. Debate: Are depression and dementia two sides of the same coin? And, if they are, how to best approach treatment? #2. Either way, the earlier the better, but it’s never too late: New book outlines the five lifestyle pillars to “build a better brain at any age” #3. “If I were a cardiologist evaluating a patient’s chest pain, for instance, I would speak with the patient, but then I would listen to their heart and measure ...
Source: SharpBrains - May 28, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Education & Lifelong Learning Technology & Innovation brain health cognitive cognitive healthcare cognitive--disorders cognitive-health Cumulus Neuroscience dementia depression neurotechnologies psychedelics Source Type: blogs

Akili Interactive Labs raises $160M in equity and debt to transform cognitive healthcare via prescription videogame treatments
Akili raises $110m to build its digital therapeutics pipeline (pharmaforum): EndeavorRx became the first and so far only approved prescription video game treatment in the US when it was cleared by the FDA last year to treat attention-deficit hyperactivity disorder (ADHD), and has also been given a green light in Europe. It is also being tested for other indications including fuzzy thinking in COVID-19 survivors, a condition sometimes known as ‘brain fog’. The new funding, which is accompanied by a $50 million loan facility, is earmarked for the continued rollout of the app as well as Akili’s pipeline of p...
Source: SharpBrains - May 26, 2021 Category: Neuroscience Authors: SharpBrains Tags: Attention & ADD/ADHD Brain/ Mental Health Technology & Innovation Akili Akili Inter­ac­tive Labs attention deficit hyperactivity disorder cognitive healthcare cognitive--disorders digital therapeutics EndeavorRx FDA Neuberger Berma Source Type: blogs

Artificial Intelligence (AI)-enabled chatbot Wysa raises $5.5M to broaden access to mental health support
Conclusions: Although bonds are often presumed to be the exclusive domain of human therapeutic relationships, our findings challenge the notion that digital therapeutics are incapable of establishing a therapeutic bond with users. Future research might investigate the role of bonds as mediators of clinical outcomes, since boosting the engagement and efficacy of digital therapeutics could have major public health benefits. News in Context: Consumer Reports finds unclear, questionable privacy practices and policies among popular mental health apps Teladoc Health, having acquired Livongo and myStrength, launches integrated ...
Source: SharpBrains - May 24, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation cognitive restructuring cognitive-behavioral-therapy digital therapeutics mental health benefits mental health platform mental healthcare mindfulness W Health Ventures Wysa Source Type: blogs

Debate: Are depression and dementia two sides of the same coin? And, if they are, how to best approach treatment?
This article was originally published on The Conversation. News in Context: Report: 35% of worldwide dementia cases could be prevented by modifying these 9 modifiable risk factors Repetitive negative thinking may increase (or perhaps be caused by) cognitive decline and Alzheimer’s pathology Study: Hearing aids may help older adults delay dementia, depression, anxiety, and falls The post Debate: Are depression and dementia two sides of the same coin? And, if they are, how to best approach treatment? appeared first on SharpBrains. (Source: SharpBrains)
Source: SharpBrains - May 21, 2021 Category: Neuroscience Authors: The Conversation Tags: Brain/ Mental Health Alzheimers-disease antidepressants cognition cognitive decline Cognitive-impairment coronavirus COVID-19 dementia depression hippocampus memory Source Type: blogs

Teladoc Health, having acquired Livongo and myStrength, launches integrated mental health service for the workplace
Teladoc builds out mental healthcare services with myStrength Complete (MobiHealthNews): Virtual care giant Teladoc is building out its behavioral health services through its latest program, myStrength Complete. The new offering is designed to give users a single integrated mental healthcare experience. It combines the app-based models of care from myStrength with Teladoc’s on-demand therapists and psychiatrists … The myStrength platform uses evidence-based clinical models such as cognitive behavioral therapy, positive psychology and mindfulness to help treat behavioral health conditions such as depression, an...
Source: SharpBrains - May 19, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation anxiety cognitive-behavioral-therapy depression digital mental health employers health plans insomnia Livongo mental health service mindfulness myStrength Complete Positive-Psychology Source Type: blogs

Study finds MDMA-assisted therapy to be safe and highly effective to treat severe PTSD
We report the findings of a randomized, double-blind, placebo-controlled, multi-site phase 3 clinical trial (NCT03537014) to test the efficacy and safety of 3,4‑methylenedioxymethamphetamine (MDMA)-assisted therapy for the treatment of patients with severe PTSD, including those with common comorbidities such as dissociation, depression, a history of alcohol and substance use disorders, and childhood trauma. After psychiatric medication washout, participants (n=90) were randomized 1:1 to receive manualized therapy with MDMA or with placebo, combined with three preparatory and nine integrative therapy sessions … The...
Source: SharpBrains - May 18, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Clinical-Trial Ecstasy MDMA MDMA-assisted therapy methylenedioxymethamphetamine Molly post-traumatic-stress-disorder psychedelics Psychotherapy PTSD severe PTSD Source Type: blogs

New book outlines the five lifestyle pillars to “build a better brain at any age”
Like many people over 60, I sometimes lose my keys or forget the names of favorite films. When I do, it makes me wonder: Is this the beginning of cognitive decline? Or, worse, am I fated to follow in the footsteps of my mother, who died of Lewy-body dementia in her 70s? According to neurosurgeon Sanjay Gupta, CNN medical correspondent and author of the new book Keep Sharp: Building a Better Brain at Any Age, the answer is no. Forgetfulness is normal at all ages, and your genes don’t doom you to dementia. What’s important is taking care of your brain in the best way possible, he argues. “You can affect you...
Source: SharpBrains - May 14, 2021 Category: Neuroscience Authors: Greater Good Science Center Tags: Brain/ Mental Health Education & Lifelong Learning brain health brain resiliency Brain-Fitness cognitive decline cognitive strengths cognitive-abilities cognitive-capacities cognitive-reserve dementia exercise forgetfulness keep Source Type: blogs

Comprehensive research review identifies most promising interventions to boost workplace mental health
This report summarises what we at Wellcome have learned from our first commission on promising approaches for addressing workplace mental health. It also sets out why businesses and researchers need to work together to take a more scientific approach to supporting mental health at work. What’s inside: findings from ten research projects that looked at the evidence behind promising approaches for supporting workplace mental health suggested actions businesses can take, based on this evidence reflections on gaps in the evidence and why it’s important for businesses and scientists to work together to understand w...
Source: SharpBrains - May 12, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health anxiety depression Flexible working mindfulness sitting Wellcome workplace workplace mental health Source Type: blogs

Study: Social media and general tech engagement not found to “fry” teenagers’ brains
Little to no increase in association between adolescents’ mental health problems and digital tech (Science Daily): With the explosion in digital entertainment options over the past several decades and the more recent restrictions on outdoor and in-person social activities, parents may worry that excessive engagement with digital technology could have long-term effects on their children’s mental health. A new study published in the journal Clinical Psychological Science, however, found little evidence for an increased association between adolescents’ technology engagement and mental health problems over th...
Source: SharpBrains - May 10, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation adolescents depression digital technology mental health problems smartphones social-media Source Type: blogs

Study: Higher mental wellbeing (in 2016) seen to lower healthcare costs (in 2017)
Conclusions: Estimated reductions in costs related to mental well-being add to what is already known about potential savings related to the prevention of mental illness. It does so by illustrating the savings that could be made by moving from lower to higher levels of mental well-being both within and beyond the clinical range. Our estimates pertain to costs associated with those health-related outcomes that were included in the study, but excluding other social and economic outcomes and benefits. They cover immediate cost estimates (costs generated the year following mental well-being measurement) and not those that could...
Source: SharpBrains - May 7, 2021 Category: Neuroscience Authors: The Conversation Tags: Brain/ Mental Health continuum mental health promotion mental wellbeing mindfulness self care Source Type: blogs

Cumulus Neuroscience raises $8.3M to develop EEG-based wireless ‘Fitbit for the brain’
Belfast-based Cumulus raises €6.9m for its ‘Fitbit for the brain’ (The Irish Times): … Formerly known as BrainWaveBank, the company has developed a wireless electroencephalogram (EEG) headset and proprietary software platform that use advanced analytics and machine learning to measure cognitive fitness. “This funding will allow us to build on the ground-breaking advances we have made in remote, frequent monitoring of brain activity and cognitive function in the home, in partnership with leading developers of digital biomarkers,” said Mr Cunningham, the company’s chief executive. &l...
Source: SharpBrains - May 5, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation Alzheimer’s Disease BrainWaveBank clinical-trials CNS CNS therapies cognitive-fitness Cumulus Neuroscience dementia Dementia Discovery Fund digital biomarkers EEG electroencephalogra Source Type: blogs

Reading Our Minds: New book issues strong call to action to modernize psychiatry
The Rise of Big Data Psychiatry (The Wall Street Journal): As a physician, I need to figure out three things when a new patient walks into my office: what their life is typically like, what has changed that made them seek treatment and what I can do to help them. It’s a complex problem, and most fields of medicine approach it by taking measurements. If I were a cardiologist evaluating a patient’s chest pain, for instance, I would speak with the patient, but then I would listen to their heart and measure their pulse and blood pressure. I might order an electrocardiogram or a cardiac stress test, tools that weren...
Source: SharpBrains - May 4, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation big data Big Data Psychiatry clinical decision tools machine-learning neural networks neurotechnologies Neurotechnology suicidal thoughts Twitter Source Type: blogs

On centenarians, memory, Mars, tDCS, ADHD, digital health, beautiful brains, and more
Hendrikje van Andel Schipper (1890–2005) Welcome to a new edition of SharpBrains’ e‑newsletter, featuring ten timely resources and research findings for lifelong brain and mental fitness. #1. Let’s start with a fascinating story and study 🙂 Study with 330 centenarians finds that cognitive decline is not inevitable … (Henne Holstege, PhD, assistant professor at Amsterdam University Medical Center) said her interest in researching aging and cognitive health was inspired by the “fascinating” story of Hendrikje van Andel Schipper, who died at age 115 in 2005 “completely cogn...
Source: SharpBrains - April 30, 2021 Category: Neuroscience Authors: SharpBrains Tags: Attention & ADD/ADHD Brain/ Mental Health Education & Lifelong Learning Technology & Innovation ADHD-Treatment aging Alzheimer’s astronauts beautiful brains brain health centenarians cognitive decline cognitive-function cogniti Source Type: blogs

Let ’s welcome Mental Health Month (May) by appreciating our beautiful brains
Self Reflected was created over two years by a team that included neuroscientists, engineers, physicists, and students, and is a hyperdetailed representation of 500,000 neurons in a sagittal slice. Credit: Greg Dunn and Brian Edwards. Between Thought and Expression (Cerebrum): Greg Dunn was on his way to a Ph.D. in neuroscience at the University of Pennsylvania when he realized that bringing the brain’s beauty to life was a more suitable role for him than lab work. He started in ink, inspired by Chinese, Japanese, and Korean paintings and the similarities he found in the microscopic world of neurons and the macroscop...
Source: SharpBrains - April 28, 2021 Category: Neuroscience Authors: SharpBrains Tags: Education & Lifelong Learning beauty Mental Health Month Microetchings neuro art neuroimaging Neurons neuroscience Neurotechnology Source Type: blogs

Ohio joins Indiana and Kentucky in funding Pear Therapeutics ’ digital addiction treatments
Ohio is third state to fund Pear’s digital therapeutics to tackle addiction (pharmaforum): The company has been pushing for more reimbursement of its three marketed DTx products in the US following a first FDA approval in 2017. Pear said that the Ohio Department of Mental Health and Addiction Services (OhioMHAS) and RecoveryOhio are providing access to Pear’s FDA-approved DTx reSET and reSET‑O, for treatment of substance use disorder and opioid use disorders, respectively. Funding is provided by the State Opioid Response (SOR) 2.0 grant, administered by OhioMHAS, and part of the US Department of Health and Hu...
Source: SharpBrains - April 26, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation addiction cognitive-behavioral-therapy digital therapeutics FDA Indiana Kentucky Ohio opioid use disorder Pear Therapeutics prescription digital therapeutics reSET reSET-O substance Source Type: blogs

Shape your environment, shape your mind
One of the biggest contributors to our happiness is something we barely pay attention to: the voice inside our own heads. As psychologist Ethan Kross describes in his new book Chatter, that voice is constantly analyzing the situations we’re in, reflecting on the past and future, and telling us who we are. While sometimes friendly and optimistic—it’s OK, everything’s going to work out!—it can also be critical and downbeat. Our inner voice can berate us for mistakes or decide our life is ruined. It can ruminate on negative emotions and experiences, dredging them up without any kind of constructi...
Source: SharpBrains - April 23, 2021 Category: Neuroscience Authors: Greater Good Science Center Tags: Education & Lifelong Learning book brain calmer mind chatter clutter declutter environment Ethan Kross feelings nature rumination thoughts Source Type: blogs

Next in NASA ’s path to Mars: Overcoming astronauts’ cognitive and mental health challenges
– Illustration by Zoë Van Dijk Space Between the Ears (Cerebrum): A few short months ago, news programs around the globe showed NASA engineers and scientists celebrating as a robot named Perseverance successfully landed on the surface of Mars. The mission: capture and share images and audio that have never been seen or heard before. As impressed as most observers were of this major milestone, many couldn’t help but wonder when we might be ready to someday send humans. While it seems the stuff of science fiction and almost inconceivable, the answer—according to recent NASA planning—is before the...
Source: SharpBrains - April 21, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Peak Performance Artemis astronauts brain-function brain-teaser cognitive cognitive-performance Gateway MaRS mental capacities mental health challenges NASA spaceflight Stress stressors Source Type: blogs

Study: Depression affects visual perception … making it more accurate
The brightness of Figures A and B is exactly the same, but they are perceived differently due to a difference in the background. This illusion was perceived similarly by the patients and healthy control subjects. The contrast of Figures C and D is exactly the same as well, but the perception of this illusion was weaker among the depressed patients than the control subjects. (Salmela et al, J. Psychiatry Neurosci, 2021) Depression affects visual perception (press release by University of Helsinki): Researchers specialised in psychiatry and psychology at the University of Helsinki investigated the effects of depression on vi...
Source: SharpBrains - April 19, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Education & Lifelong Learning behavioural tests Cerebral Cortex cortical processing depression electrophysiology perception tests psychiatry Psychology visual-perception Source Type: blogs

Emerging applications of transcranial Direct Current Stimulation (tDCS): e ‑sports skills training, cognitive enhancement in older adults
10 Minutes of Electrical Stimulation During Gaming Helps Improve e‑Sports Skills (Technology Networks): Researchers at Lero, the Science Foundation Ireland Research Centre for Software and University of Limerick (UL), have found video gamers can significantly improve their esport skills by training for just 10 minutes a day. The research team at Lero’s Esports Science Research Lab (ESRL) at UL also found novice gamers benefited most when they wore a custom headset delivering transcranial Direct Current Stimulation (tDCS) for 20 minutes before training sessions. Participants wore a custom headset (HALO Neuroscience&...
Source: SharpBrains - April 16, 2021 Category: Neuroscience Authors: SharpBrains Tags: Peak Performance Technology & Innovation cognitive-enhancement cognitive-performance Cognitive-Training e-sports electrical stimulation Gaming Halo Neuroscience healthy older adults Lero tDCS Transcranial-direct-current-stimulation Source Type: blogs

Does ADHD treatment enable long-term academic success? (Yes, especially when pharmacological and non-pharma treatments are combined)
Academic difficulties are one of the most important adverse consequences of ADHD, and they frequently contribute to parents’ decision to seek treatment for their child. Whether treatment consistently yields a positive impact on long-term academic success is thus an important issue; however, the answer to this question has been somewhat controversial. A study published recently in the Journal of Attention Disorders, Long-term outcomes of ADHD: Academic achievement and academic performance, represents the most comprehensive effort to date to identify and synthesize research related to this important question. The Study...
Source: SharpBrains - April 14, 2021 Category: Neuroscience Authors: Dr. David Rabiner Tags: Attention & ADD/ADHD Brain/ Mental Health academic difficulties AD/HD-treatments long-term academic success non-pharmacological Source Type: blogs

Study with 330 centenarians finds that cognitive decline is not inevitable
Hendrikje van Andel Schipper (1890–2005) Age-Related Cognitive Decline May Not Be Inevitable (WebMD): It is often assumed that a decrease in memory and brain function are inevitable parts of aging, but a new study of centenarians suggests otherwise. Investigators found that despite the presence of neurological issues generally associated with Alzheimer’s disease (AD), many centenarians maintained high levels of cognitive performance. (Henne Holstege, PhD, assistant professor at Amsterdam University Medical Center) said her interest in researching aging and cognitive health was inspired by the “fascinating...
Source: SharpBrains - April 13, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Education & Lifelong Learning aging assessments brain resilience brain-reserve centenarians cognitive decline cognitive resilience cognitive trajectories cognitive-performance cognitive-reserve Mini-Mental Stat Source Type: blogs

Final 3 weeks to nominate teachers for the $1M Global Teacher Prize 2021
Dear friends, We hope you are doing well. There is now less than one month to go until applications and nominations close for the Global Teacher Prize, and we wanted to ask you to help us spread the word. We are now starting the seventh cycle of this prize, which continues to highlight the important work of extraordinary teachers around the world. Now more than ever, it is important they are recognised for their contribution and have a seat at the table when decisions are made on education. Teachers applying for the Global Teacher Prize will be assessed on teaching practices, how they innovate to address local challenges, ...
Source: SharpBrains - April 8, 2021 Category: Neuroscience Authors: The Varkey Foundation Tags: Education & Lifelong Learning Global Teacher Prize Lifelong-learning teachers Varkey Foundation Source Type: blogs

From digital therapeutics to personalized mental health solutions: Pear Therapeutics expands platform via partnerships with Empatica, etectRx, KeyWise, and Winterlight
Pear Therapeutics Expands Platform with Digital Biomarkers, Machine Learning Algorithms and Sensor-Based Technologies (press release): Pear Therapeutics, Inc. announced today that it has entered into agreements with multiple technology companies, including Empatica Inc., etectRx, Inc., and KeyWise, Inc. The new technologies complement the voice-based biomarkers previously licensed from Winterlight Labs. These new agreements bolster Pear’s Prescription Digital Therapeutics (PDT) platform, by adding to its library of digital biomarkers, machine learning algorithms, sensor-based technologies, and digital therapeutics. T...
Source: SharpBrains - April 7, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation digital biomarkers digital therapeutics Empatica etectRx KeyWise Pear Therapeutics WinterLight Labs Source Type: blogs

Neuroscientist Lisa Genova, author of the beautiful novel Still Alice, releases non-fiction book on Memory
A Neuroscientist’s Poignant Study of How We Forget Most Things in Life (The New Yorker): Any study of memory is, in the main, a study of its frailty. In “Remember,” an engrossing survey of the latest research, Lisa Genova explains that a healthy brain quickly forgets most of what passes into conscious awareness. The fragments of experience that do get encoded into long-term memory are then subject to “creative editing.” To remember an event is to reimagine it; in the reimagining, we inadvertently introduce new information, often colored by our current emotional state. A dream, a suggestion, an...
Source: SharpBrains - April 5, 2021 Category: Neuroscience Authors: SharpBrains Tags: Education & Lifelong Learning book healthy-brain long-term-memory neuroscientist non-fiction book remember Source Type: blogs

On Awe, Wonder, Biofeedback, CBSM, Virtual Reality, Privacy, Being Wrong, and more
Welcome to a new edition of SharpBrains’ e‑newsletter, this time featuring eleven timely resources and research findings for lifelong brain health and mental well-being. #1. “Awe is the feeling we experience when encountering vast things that we don’t understand. Around the world and in culturally varying ways, studies show, we experience awe in response to others’ kindness and courage, nature, music, religious or spiritual practice, the visual and dramatic arts, and epiphany … It leads us to share, collaborate, and wonder. In experiences of awe, people often speak as if they have found the...
Source: SharpBrains - March 31, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Education & Lifelong Learning Peak Performance Technology & Innovation Applied Neuroscience AppliedVR awe biofeedback Blue Note Therapeutics CBSM consumer-reports digital health Happify Health heart-rate-vari Source Type: blogs

Growing research supports Heart Rate Variability (HRV) biofeedback training to lower stress and anxiety, increase sports performance
Conclusions: HRV biofeedback training is associated with a large reduction in self-reported stress and anxiety. Although more well-controlled studies are needed, this intervention offers a promising approach for treating stress and anxiety with wearable devices. Effect of Heart Rate Variability Biofeedback on Sport Performance, a Systematic Review (Applied Psychophysiology and Biofeedback ) Abstract: Aim is to determine if the training with heart rate variability biofeedback allows to improve performance in athletes of different disciplines. Methods such as database search … All studies had a small sample size (ra...
Source: SharpBrains - March 29, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Peak Performance Technology & Innovation ambulatory monitoring anxiety athletic performance athletic training biofeedback biofeedback training exercise heart-rate-variability HRV lower anxiety lower stress Source Type: blogs

To prevent “cognitive entrenchment,” think like a scientist and be wrong often
In a rapidly changing world, it’s important to be able to adapt and change rather than stubbornly adhering to old ideas and opinions. This was one of the lessons of 2020, a year that forced us to question many of our assumptions about what behaviors are safe, how work and school can be conducted, and how we connect with others. “In a changing world, you have to be willing and able to change your mind. Otherwise, your expertise can fail, your opinions get out of date, and your ideas fall flat,” says organizational psychologist Adam Grant, author of the new book Think Again: The Power of Knowing What You Do...
Source: SharpBrains - March 25, 2021 Category: Neuroscience Authors: Greater Good Science Center Tags: Education & Lifelong Learning Adam Grant book cognitive cognitive entrenchment knowing Think Again Source Type: blogs

AppliedVR raises $29M to help make virtual reality the standard of care for treating chronic pain
AppliedVR Raises $29 Million for Immersive Headsets (LA Business Journal): Century City-based AppliedVR, Inc. announced March 23 that it has raised $29 million in Series A funding that will be used to continue development of an immersive headset to help patients with chronic pain. … The company is building a headset called EaseVRx that will display immersive environments like campfires, mountains and other animated nature scenes to help patients dealing with chronic pain, including fibromyalgia and chronic intractable lower back pain… AppliedVR Chief Executive and co-founder Matthew Stoudt said that the ...
Source: SharpBrains - March 24, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation AppliedVR chronic pain cognitive behavioral therapies FDA fibromyalgia headset mindfulness exercises pain treatment virtual-reality Source Type: blogs