On Brain Awareness Week, mental health innovation, tDCS, biofeedback, psychedelics, and more
Welcome to a new edition of SharpBrains’ e‑newsletter, starting with some ideas to get in the mood for Brain Awareness Week next month (March 15–21st). May BAW 2021 be a hundred times more upbeat than last year’s… #1. Seven brain teasers and a neuroplasticity podcast to celebrate Brain Awareness Week 2021 #2. Imagine what this capability may mean just a few years from now. Should/ will Google alert Gmail users about their (future) cognitive status? Study: Artificial intelligence program identifies linguistic markers that predict, with 70% accuracy, who gets Alzheimer’s Disease years la...
Source: SharpBrains - February 26, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health SharpBrains Monthly eNewsletter Technology & Innovation behavioral biofeedback Brain Teasers cognitive Halo Neuroscience Humanest Care Koa Health mental healthcare Mightier Modern Health neuroplasticity psy Source Type: blogs

Four trends accelerating mental health innovation in the COVID/ post-COVID era
The money behind mental health: How the pandemic increased innovation, investment in behavioral health care (Fierce Healthcare): Earlier this month, Modern Health marked a milestone few companies ever reach: unicorn status. With the help of its latest $74 million funding round, the startup, which serves as a mental health benefits platform for employers, topped a $1 billion valuation. … And while Modern Health was already attracting plenty of interest before the pandemic, CEO Alyson Watson said her company is among those in the behavioral health space that have seen what can only be described as a seismic shift acro...
Source: SharpBrains - February 24, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation Behavioral Health COVID-19 digital behavioral health employers mental health benefits mental health innovation Modern Health Source Type: blogs

Growing research points to expanding adoption of online cognitive behavioral therapies, both guided and unguided
We are seeing a number of fascinating meta-analyses comparing the value of A) face-to-face vs. Internet-based cognitive behavioral therapies and B) guided vs unguided internet-based cognitive behavioral therapy, especially in the case of depression. Here you have a couple great examples, suggesting a growing adoption in the near future of web-based, and increasingly personalized, interventions. A) A comparison of electronically-delivered and face to face cognitive behavioural therapies in depressive disorders: A systematic review and meta-analysis (Eclinical Medicine). From the Abstract: Background: Cognitive behavioural ...
Source: SharpBrains - February 22, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation CBT cognitive behavioral therapies depression eCBT Internet-based cognitive behavioral therapies Source Type: blogs

Neuromodulation developer Halo Neuroscience closes its doors; Flow Neuroscience acquires assets
Flow acquires brain stimulation technology developer Halo (Medical Device Network): Flow Neuroscience has acquired the assets of brain stimulation technology developer Halo Neuroscience to advance its research into depression and other mental health disorder treatments. The financial details of the deal have not been disclosed. Using Halo’s research in neuromodulation field, Flow Neuroscience plans to enhance its current medically certified tDCS headset for depression … A form of neuromodulation, tDCS uses constant, low direct current delivered via electrodes on the head. In July 2019, Flow announced that it r...
Source: SharpBrains - February 19, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Peak Performance Technology & Innovation brain stimulation depression Flow Neuroscience Halo Neuroscience headset neuromodulation tDCS Transcranial-direct-current-stimulation Source Type: blogs

Seven brain teasers and a neuroplasticity podcast to celebrate Brain Awareness Week 2021
Brain Awareness Week 2021 takes place next month. Why not start celebrating now by challenging our minds and discussing the latest about lifelong neuroplasticity? Here’s a selection of seven stimulating brain teasers that readers enjoyed the most in 2020: Please consider Linda’s job prospects Explore your perceptual biases Think outside the box with a few fun riddles Complete these proverbs and exercise your memory and reasoning Where do words go? Test your stress level if you dare… Which way is the bus heading? And here’s the podcast where Eric White interviews our very own Alvaro Fernandez...
Source: SharpBrains - February 17, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain Teasers Brain/ Mental Health Education & Lifelong Learning brain-awareness-week Lifelong Neuroplasticity podcast Source Type: blogs

Digital mental health start-up Koa Health raises €30M to accelerate growth in Europe and the US
Mental healthcare startup Koa Health closes €30M Series A funding to expand its international footprint (Silicon Canals): In a recent development, Barcelona-based digital mental healthcare provider, Koa Health, has announced it closed an oversubscribed €30M Series A funding round … The company had raised the funds back in October 2020 and had also announced its spin-out from Alpha, Telefónica’s startup factory. The raised capital will be used to boost Koa Health’s growth and expand its international footprint including the US. Oliver Harrison, CEO of Koa Health says, “We know ...
Source: SharpBrains - February 16, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation Alpha digital mental health Koa Health mental healthcare Oliver Harrison startup Telefónica Source Type: blogs

Survey finds concerns AND hope to address growing mental health needs due to the covid pandemic
This study provides proof-of-concept of the viability for researchers and private companies to work collaboratively toward a common good. Digital services providers reported a diverse range of mental health concerns. A recurring observation is that demand for digital mental health support has risen, and that the nature of this demand has also changed since COVID-19, with an apparent increased presentation of anxiety and loneliness. News in Context: Three ways to protect your mental health during –and after– COVID-19 The landscape of digital mental health apps: huge unmet needs, quality concerns, app stores as...
Source: SharpBrains - February 11, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation anxiety COVID-19 digital health digital mental health Humanest Care loneliness mental health apps Mental Health Tsunami mental healthcare ORCHA Source Type: blogs

Can biofeedback-based videogames help children better manage stress? Magellan Health and Mightier secure $2 million NIMH grant to investigate
This study’s goal is to validate that digital tools like Mightier can improve health outcomes, lower the cost of care and increase access to mental healthcare” said Matthew Miller, senior vice president, behavioral health, Magellan Healthcare. About the grant: The research is supported by the National Institute Of Mental Health of the National Institutes of Health under Award Number R44MH124574. The NIMH supports scientists, clinicians, and research personnel at universities, medical schools, hospitals, small businesses, and other institutions via grants, contracts, and cooperative agreements. Researchers at NI...
Source: SharpBrains - February 10, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation Behavioral Health biofeedback biofeedback video game heart rate-monitor Magellan Health mental health disorders Mightier NIMH regulate stress video-games videogame wearable Source Type: blogs

The landscape of digital mental health apps: huge unmet needs, quality concerns, app stores asked to ensure transparency
Addressing the mental health crisis (Pharma Field): Each day we find out more about the mental health effects of the pandemic. Early on, the Office for National Statistics found that one in five Britons reported symptoms of depression, compared with one in 10 before. And, according to a recent study led by the University of Nottingham and King’s College London, stress, anxiety and depression were all significantly higher in participants compared with ‘population norms’, with 64% of the participants reporting symptoms of depression and 57% reporting symptoms of anxiety. … Through simple force of nec...
Source: SharpBrains - February 5, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation advertising standards cognitive behavioural therapy consumer protection digital health digital health applications digital mental health digital mental health interventions digital therapeutic Source Type: blogs

Next: Psychedelic-assisted psychotherapy?
How ecstasy and psilocybin are shaking up psychiatry (Nature): … The Imperial study was one of a spate of clinical trials launched over the past few years using illicit psychedelic drugs such as psilocybin, lysergic acid diethylamide (LSD) and MDMA (3,4‑methylenedioxymethamphetamine, also known as molly or ecstasy) to treat mental-health disorders, generally with the close guidance of a psychiatrist or psychotherapist. The idea has been around for decades — or centuries in some cultures — but the momentum has picked up drastically over the past few years as investors and scientists have begun to champi...
Source: SharpBrains - February 4, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Books lysergic acid diethylamide MDMA mental health disorders psilocybin psychedelic psychiatrist psychotherapist Psychotherapy Source Type: blogs

Study: Artificial intelligence program identifies linguistic markers that predict, with 70% accuracy, who gets Alzheimer ’s Disease years later
Fig. 3. Cookie-theft picture description task (CTT) examples from the Framingham Heart Study, including an unimpaired sample (a), an impaired sample (b), and an even more impaired sample showing significant misspellings and minimal grammatic complexity ©. Credit: Eyigoz et al (2020) Alzheimer’s Prediction May Be Found in Writing Tests (The New York Times): … the researchers looked at a group of 80 men and women in their 80s — half had Alzheimer’s and the others did not. But, seven and a half years earlier, all had been cognitively normal. The men and women were participants in the Framingham H...
Source: SharpBrains - February 3, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation Alzheimers-disease artificial intelligence biomarker clinical-diagnosis cognitive decline Cognitive-tests cognitively dementia Framingham Heart Study impairment linguistic analysis MCI Source Type: blogs

The latest on brain health, neurotechnology, artificial intelligence and “never stop wondering”
Welcome to a new edition of SharpBrains’ e‑newsletter, featuring a life well lived, the latest news on brain health and innovation, and some brain teasers in honor of International Brain Teaser Month. #1. Thank you, Sharon. We won’t. “Never stop wondering” — Sharon Begley, science journalist, RIP #2. Write injuries in sand, kindnesses in ____________. Milk the cow, but do not pull off the ___________. Enjoy these 5 US and 7 international proverbs to test your cognitive skills. #3. Beware the snakes as you tease your mind with this optical illusion. #4. The blood-brain barrier is hopefully ha...
Source: SharpBrains - January 29, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation artificial intelligence brain health Brain Teasers brain-teaser cognitive neurocognitive Neurotechnology Source Type: blogs

If you ’re a fruit fly, tease your mind with this optical illusion. Humans welcome too.
This study shows how illusions can provide insight into visual processing mechanisms and principles across phyla. More fun illusions and brain teasers: Three quick brain teaser games to test your perceptual and cognitive skills Test your Brain with these 10 Visual Illusions Top 25 fun Brain Teasers and Puzzles 12 fun riddles to welcome a sharp new year What are cognitive abilities and how to boost them? The post If you’re a fruit fly, tease your mind with this optical illusion. Humans welcome too. first appeared on SharpBrains. (Source: SharpBrains)
Source: SharpBrains - January 26, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain Teasers cognitive cognitive-skills optical illusion optical-illusions perception rotating snake illusion visual-perception Source Type: blogs

FDA releases first Artificial Intelligence (AI) regulatory plan to promote responsible digital health innovation
FDA Releases Artificial Intelligence/Machine Learning Action Plan (FDA press release): Today, the U.S. Food and Drug Administration released the agency’s first Artificial Intelligence/Machine Learning (AI/ML)-Based Software as a Medical Device (SaMD) Action Plan. This action plan describes a multi-pronged approach to advance the Agency’s oversight of AI/ML-based medical software … The AI/ML-Based Software as a Medical Device Action Plan outlines five actions that the FDA intends to take, including: Further developing the proposed regulatory framework, including through issuance of draft guidance on a pr...
Source: SharpBrains - January 25, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation artificial intelligence digital health digital health innovation FDA Food and Drug Administration machine-learning regulatory framework software Source Type: blogs

Study: Wearable sensors and machine learning may well (one day) help detect a broad range of epileptic seizures
Conclusion: Automatic epileptic seizure detection using machine learning and wearables data is feasible. Preliminary results show better-than-chance seizure detection across a broad range of epileptic seizures. Future improvements may consider clinical chrono-epileptological variables, such as seizure duration, semiology, and etiology or syndrome, and alternative data balancing, pre- and post-processing, fusion and ensemble learning methods. Thus, while findings suggest feasibility, performance following future adjustments may improve further. News in Context: Special Issue: Seizure detection and mobile health devices in...
Source: SharpBrains - January 22, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation acceptability deep learning EEG epilepsy mHealth seizure detection wearables Source Type: blogs

“Never stop wondering” — Sharon Begley, science journalist, RIP
This article was adapted by arrangement with Hudson Street Press, a member of Penguin Group (USA) Inc., from The Emotional Life of Your Brain: How Its Unique Patterns Affect the Way You Think, Feel, and Live–and How You Can Change Them by Richard J. Davidson, Ph.D., and Sharon Begley. Copyright by Richard J. Davidson, Ph.D., and Sharon Begley.The post “Never stop wondering” — Sharon Begley, science journalist, RIP first appeared on SharpBrains. (Source: SharpBrains)
Source: SharpBrains - January 21, 2021 Category: Neuroscience Authors: Alvaro Fernandez Tags: Education & Lifelong Learning books on brain brain-functions Courtney Nobile emotional style Emotions neuroplasticity relationships Resiliency Richard-Davidson Sharon-Begley Source Type: blogs

Can COVID-19 coronavirus “invade” human brain tissue? (Quick answer: evidence so far is mixed)
Brain scans show lower part of a COVID-19 patient’s brain stem, postmortem. Arrows point to light and dark spots suggesting blood vessel damage, without signs of infection by the coronavirus that causes COVID-19. Credit: National Institute of Neurological Disorders and Stroke, NIH Taking a Closer Look at COVID-19’s Effects on the Brain (NIH Director’s blog): While primarily a respiratory disease, COVID-19 can also lead to neurological problems. The first of these symptoms might be the loss of smell and taste, while some people also may later battle headaches, debilitating fatigue, and trouble thinking cle...
Source: SharpBrains - January 19, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health brain fog brain tissue brainstem COVID-19 human-brain neurological neurological problems Neurons NIH Source Type: blogs

Neuroimaging, big data and mental health: A survey of the land
This figure shows how different brain networks function together; the lines measuring the strength of communication among various networks. By using such displays, we can evaluate what is called the human functional connectome—and also how mental illness is disrupted. [Figure courtesy of Vince Calhoun] Mental and degenerative disorders are among the most costly and common causes of disability in society today. Because the brain is the most complex organ in the human body, diagnosing and treating problems when things go wrong poses enormous challenges. Even before the 1990s was designated the Decade of the Brain, the ...
Source: SharpBrains - January 15, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation artificial intelligence brain-machine interface degenerative disorders neuroimaging psychiatry virtual-reality Source Type: blogs

Neurostimulation device GammaSense by Cognito Therapeutics secures FDA Breakthrough Device Designation to explore Alzheimer ’s Disease applications
Credit: The Picower Institute @ MIT Cognito Therapeutics nets FDA breakthrough label for light, sound therapy for Alzheimer’s disease (Fierce Biotech): Using specific frequencies of flashing lights and sounds to stimulate the brain’s electrical activity, Cognito Therapeutics believes it can help treat Alzheimer’s disease by energizing neurons and reactivating the immune system. Described as similar to a strobe light, but much faster, Cognito’s GammaSense stimulation system is built into a pair of opaque glasses worn with a set of headphones. The daily treatment has shown positive effects in mice, w...
Source: SharpBrains - January 14, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation amyloid plaques breakthrough device breakthrough therapy cognitive-symptoms Cognito Therapeutics digital therapeutics FDA GammaSense hippocampus neurodegenerative-diseases neuromodulatio Source Type: blogs

The new frontier in neurocognitive monitoring and dementia screening: the Apple Watch
Biogen to Launch Pioneering Study to Develop Digital Biomarkers of Cognitive Health Using Apple Watch and iPhone (press release): Biogen Inc. (Nasdaq: BIIB) today announced a new virtual research study, in collaboration with Apple, to investigate the role Apple Watch and iPhone could play in monitoring cognitive performance and screening for decline in cognitive health including mild cognitive impairment (MCI). The multi-year, observational research study will be launched later in 2021 and will enroll participants including young and aging adults with a range of cognitive performance. Driven by the powerful technology in A...
Source: SharpBrains - January 12, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation Apple Biogen cognitive-health detect cognitive impairment detect dementia digital biomarkers iPhone MCI memory-loss mild-cognitive-impairment neurocognitive neuroscience werables Source Type: blogs

Fun brain teaser to test your cognitive skills during International Brain Teaser Month
Memory relies mostly on the temporal lobes (see green area) and also the frontal lobes (red), so those are the areas that will get some good neuronal activation when readers raised in the US try to remember the missing words in the American proverbs below. Now, if you were raised outside the US and are not familiar with those proverbs you will have to use your reasoning skills more than your memory skills — In that case, frontal lobe activation will be wider and more intense. Conversely, if you were raised in the US you will find the international proverbs below to be more challenging. You will not be able to remembe...
Source: SharpBrains - January 8, 2021 Category: Neuroscience Authors: Dr. Pascale Michelon Tags: Brain Teasers brain puzzles for adults Brain-games brain-puzzles brain-teaser-puzzles cognitive-exercise frontal-lobes improve-memory International Brain Teaser Month logic-puzzle logical-skills mind-teasers proverbs puzzle games Source Type: blogs

Machine learning study finds standardized brain scan biomarker to detect depression with 66% accuracy
New Study Brings Biomarkers For Depression Closer To The Clinic (Forbes): Scientists have been studying biological signs of depression in the brain, looking for markers that could be used to identify the disorder. A team of scientists recently developed a technique using machine learning that can identify whether a given patient’s brain scan shows one of depression’s neural signatures… Clinicians currently diagnose major depressive disorder, commonly called depression, based on a patient’s reported symptoms, like changes in mood, activity enjoyment, appetite or sleeping, for example. But people wit...
Source: SharpBrains - January 6, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation brain markers brain-scan clinical applicability depression EEG machine-learning neural signature neural signatures neuroscience Source Type: blogs

Tip: To manage stress, sleep better. To sleep better, keep a good routine and manage stress.
Disrupted routines and worries about coronavirus have made it harder for us to sleep this year. For example, reports suggest there was a 15% increase in prescriptions for sleep medication prescriptions at the beginning of the pandemic in the U.S., and a 37% increase in insomnia in China. Importantly, if you’ve been feeling out of sorts over the past few months, the lack of sleep could be partly to blame. According to new research conducted before the pandemic, sleep deprivation dampens our enthusiasm about positive events, and makes it harder to find the silver linings when we’re under stress. In the paper, pub...
Source: SharpBrains - January 4, 2021 Category: Neuroscience Authors: Greater Good Science Center Tags: Brain/ Mental Health emotionally Emotions improving sleep insomnia psychologically Stress Source Type: blogs

Here ’s a toast to a Healthy, Happy & Meaningful New Year!
“Thinking about you” — classic Mafalda by Joaquín Salvador Lavado Tejón, known as Quino, who left us in 2020 to explore future endeavors And, if you’re looking for New Year Resolutions, here you can find some inspiration and ideas…  1. To harness neuroplasticity, start with enthusiasm 2. How learning changes your brain 3. What you should know about neuroplasticity and dance 4. Three ways to protect your mental health during –and after– COVID-19 5. Can you grow your hippocampus? Yes. Here’s how, and why it matters 6. Five reasons the future of bra...
Source: SharpBrains - December 31, 2020 Category: Neuroscience Authors: SharpBrains Tags: Education & Lifelong Learning Brain-Fitness cognitive-abilities hippocampus neuroplasticity New-Year-Resolutions Source Type: blogs

Update: Understanding Brain Health via Cosmological Health, and vice versa
LEFT: SECTION OF CEREBELLUM, WITH MAGNIFICATION FACTOR 40X, OBTAINED WITH ELECTRON MICROSCOPY (DR. E. ZUNARELLI, UNIVERSITY HOSPITAL OF MODENA); RIGHT: SECTION OF A COSMOLOGICAL SIMULATION, WITH AN EXTENSION OF 300 MILLION LIGHT-YEARS ON EACH SIDE (VAZZA ET AL. 2019 A&A). CREDIT: UNIVERSITY OF BOLOGNA Welcome to a new edition of SharpBrains’ e‑newsletter, featuring fascinating findings, books and resources for lifelong brain health. #1. “The human brain (section; left image above) functions thanks to its wide neuronal network that is deemed to contain approximately 69 billion neurons. On the other hand, t...
Source: SharpBrains - December 29, 2020 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health SharpBrains Monthly eNewsletter Technology & Innovation adhd ADHD-Treatment Books brain health brain-reserve Calm Click Therapeutics cognitive cognitive problems digital therapeutics Neurons neuroplasticity Source Type: blogs

Three favorite 2020 books on parenting and mental health
For a lot of families, parenting has never been harder than it was this year. Many have been struggling for months trying to provide child care and schooling at home while simultaneously working either alongside their children or as essential workers in the community, if they haven’t already lost their jobs. The theme that emerges across our favorite parenting books of the year is how important connection and communication are. These 2020 books offer science-based practical tips and sample scripts to help you communicate better with your children, build closer relationships, and set them up for happiness and resilien...
Source: SharpBrains - December 28, 2020 Category: Neuroscience Authors: Greater Good Science Center Tags: Brain/ Mental Health Education & Lifelong Learning anxiety Books brains confidence emotional competence optimism Parenting wired Source Type: blogs

Happy Holidays, Merry Christmas, Feliz Navidad!
– Celebrating the holidays in MiamiThe post Happy Holidays, Merry Christmas, Feliz Navidad! first appeared on SharpBrains. (Source: SharpBrains)
Source: SharpBrains - December 24, 2020 Category: Neuroscience Authors: SharpBrains Tags: Uncategorized Source Type: blogs

On becoming a psychotherapy pioneer and bestselling writer: A fantastic memoir by, and window into, the unique mind of Irvin D. Yalom
If you’re interested in the life of the mind, here you have an awesome window into a unique mind — a profound memoir by bestselling writer and psychotherapy pioneer Irvin D. Yalom. It was published back in 2017 but, like good wine, it has aged well and is more relevant today than ever. Irvin D. Yalom, MD, is an emeritus professor of psychiatry at Stanford University and a psychiatrist in private practice in San Francisco. He is the author of many books, including Love’s Executioner, The Theory and Practice in Group Psychotherapy, and When Nietzsche Wept. He lives with his wife in Palo Alto, California. De...
Source: SharpBrains - December 23, 2020 Category: Neuroscience Authors: Alvaro Fernandez Tags: Education & Lifelong Learning book Irvin D. Yalom memoir mind psychiatry Psychotherapy Source Type: blogs

Buyer beware: The story of a pricey and “credentialled” program to end Alzheimer’s Disease
When her husband was diagnosed with early-stage Alzheimer’s disease in 2015, Elizabeth Pan was devastated by the lack of options to slow his inevitable decline. But she was encouraged when she discovered the work of a UCLA neurologist, Dr. Dale Bredesen, who offered a comprehensive lifestyle management program to halt or even reverse cognitive decline in patients like her husband. After decades of research, Bredesen had concluded that more than 36 drivers of Alzheimer’s cumulatively contribute to the loss of mental acuity. They range from chronic conditions like heart disease and diabetes to vitamin and hormo...
Source: SharpBrains - December 22, 2020 Category: Neuroscience Authors: Kaiser Health News Tags: Brain/ Mental Health aging Alzheimer’s Disease cognitive decline Dale Bredesen dementia end Alzheimer's Disease nutritional supplements Source Type: blogs

Survey of 2500 families finds what ADHD treatments seem to work/ not work as applied in the real world
Credit: CDC Vital Signs While carefully controlled clinical trials are essential for establishing scientific support for different ADHD treatments, it is also important to examine how parents feel about the treatments they actually select for their child. How parents feel about ADHD treatments they have tried for their child provides an important complement to published clinical trials data, and can also help guide parents’ treatment choices. Results from a survey conducted by ADDitude Magazine of nearly 2500 parents provides helpful data on this question. In this survey, parents were asked about how helpful the...
Source: SharpBrains - December 17, 2020 Category: Neuroscience Authors: Dr. David Rabiner Tags: Attention & ADD/ADHD AD/HD-treatments ADHD coaching alternative ADHD treatments behavior-therapy brain training cognitive-abilities diet exercise medication mindfulness-meditation minerals Neurofeedback parents prescription p Source Type: blogs

Calm raises $75 million, expands into corporate mental health and wellness
Calm Meditation App Hits $2 Billion Value With Lightspeed, Goldman Backing (Bloomberg News): Calm, maker of a meditation, sleep and relaxation app, doubled its valuation to $2 billion after raising capital from existing backers including Lightspeed Venture Partners, TPG and Insight Partners. “With companies now taking mental well-being at work seriously, there’s so much opportunity, and we raised capital to be able to put the foot down on the gas even more,” co-founder and co-Chief Executive Officer Alex Tew said in an interview with Bloomberg … Calm says it has more than 100 million downloads and ...
Source: SharpBrains - December 15, 2020 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation Calm Insight Partners Lightspeed Venture Partners mckinsey meditation app mental well being mental-wellness relaxation app TPG valuation work workforce Source Type: blogs

Read, Play, Train: 3 Resolutions and 36 Gift Ideas for a Happier & Healthier 2021
Dear reader, We’d like to share something special. As we start to celebrate the holidays and welcome a much needed new year, we asked our team and trusted advisors to compile a list of gift (and self-gift) ideas to help us stay sane and healthy in months ahead, prioritizing three habits which have been shown to promote brain health, resilience and positive neuroplasticity: Read: Here’s a selection of 12 fascinating books to add healthy novelty, variety and challenge to our reading lives — and therefore to our brains and minds Play: Here are 12 creative and (mostly) collaborative board games. A peaceful up...
Source: SharpBrains - December 14, 2020 Category: Neuroscience Authors: Alvaro Fernandez Tags: Brain/ Mental Health Education & Lifelong Learning brain health gift ideas neuroplasticity New-Year-Resolutions Source Type: blogs

Pear Therapeutics raises $80M; finds cost savings of $2,150 per patient with opioid use disorder
Pear Therapeutics raises $80M in push for reimbursement (MedCity News): Pear Therapeutics raised $80 million in funding, which it plans to use as part of a push for coverage of its digital therapeutics. The Boston-based company has three FDA-cleared products, including digital therapeutics for substance use disorder, opioid use disorder, and most recently, insomnia. SoftBank’s Vision Fund 2 led the series D funding round. Several of Pear’s existing investors, including Novartis, also participated. The startup develops software tools to be used either in tandem with or instead of medication … Pear ha...
Source: SharpBrains - December 11, 2020 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation cost savings digital therapeutics neurobehavioral therapy opioid use disorder Pear Therapeutics reSET-O SoftBank Source Type: blogs

Reminder: Promoting Brain Health for Life, December 15 –16th
We need a new approach to promote Brain Health for Life: instead of trying to treat diseases, we need to educate and empower the public at large to adopt lifelong healthy lifestyles. In parallel, we need to better understand brain resilience and its mechanisms to design interventions that promote it and delay the onset of clinical manifestations of disease, and the consequent disability. With this 2‑day event we aim to engage relevant stakeholders and grow the leaders of tomorrow by analyzing modifiable lifestyles as nutrition, sleep, exercise, social or psychological factors, among others, and to help promote brain resi...
Source: SharpBrains - December 9, 2020 Category: Neuroscience Authors: Institut Guttmann Tags: Brain/ Mental Health Technology & Innovation brain health brain resilience brain-reserve EIT European Institute of Innovation & Technology Source Type: blogs

Understanding Brain Health via Cosmological Health, and vice versa
Discussion: “We have presented a detailed comparison between the neuronal network and the cosmic web, two of the most fascinating and complex networks in Nature, with the goal of assessing the level of similarity between these two physical systems in an objective way…Together with the rest of the analysis presented in this work, such similarities are meant to motivate the development of more powerful and discriminating algorithms to pinpoint analogies and differences of these fascinating systems, almost at the conceivable extremes of spatial scales in the Universe.” The Study in Context: Understand you...
Source: SharpBrains - December 8, 2020 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health brain health galaxies human-brain morphology network analysis Neurons neuroscience Universe Source Type: blogs

Click Therapeutics raises $30 million in debt to advance commercialization of smoking cessation app Clickotine
Click Therapeutics Secures $30M in Growth Capital from K2 HealthVentures to Expand Operations (press release): Click Therapeutics, Inc. (“Click”), a leader in Digital Therapeutics solutions as prescription medical treatments, today announced $30 million in debt financing from K2 HealthVentures (K2HV), a healthcare-focused specialty finance company, to accelerate commercialization of its leading smoking cessation solution, Clickotine, and to advance its pipeline of clinically-validated digital therapeutics… Click Therapeutics has recently announced the achievement of key corporate milestones, including se...
Source: SharpBrains - December 4, 2020 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation Click Therapeutics Clickotine digital therapeutics K2 HealthVentures medical treatments neurotechnologies non-invasive neurotechnologies prescription Source Type: blogs

Indian teacher Ranjitsinh Disale wins annual $1M Global Teacher Prize; shares half with 9 finalists
Top teacher wins $1m and gives half away (BBC News): Mr Disale, who teaches in the Zilla Parishad Primary School, in the drought-prone village of Paritewadi, in the western Indian state of Maharashtra, was named the world’s most exceptional teacher, ahead of 12,000 other nominations … He also provides online science lessons for pupils in 83 countries and runs an international project building connections between young people in conflict zones. “The Covid pandemic has dealt a severe blow to education systems around the world… but it is the contribution of teachers during these difficult time...
Source: SharpBrains - December 3, 2020 Category: Neuroscience Authors: SharpBrains Tags: Education & Lifelong Learning Global Teacher Prize Ranjitsinh Disale Source Type: blogs

Questionable “Alzheimer’s blood test” goes on sale prior to FDA approval
First blood test to help diagnose Alzheimer’s goes on sale (NBC News): A company has started selling the first blood test to help diagnose Alzheimer’s disease, a leap for the field that could make it much easier for people to learn whether they have dementia. It also raises concern about the accuracy and impact of such life-altering news. Independent experts are leery because key test results have not been published and the test has not been approved by the U.S. Food and Drug Administration — it’s being sold under more general rules for commercial labs. The test is not intended for general screening...
Source: SharpBrains - December 1, 2020 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Alzheimer's blood test Alzheimer’s Disease amyloid amyloid buildup amyloid hypothesis blood-test dementia FDA Food and Drug Administration Source Type: blogs

The latest on Brain Health and Resilience, plus a few fun Brain Teasers
Welcome to a new edition of SharpBrains’ e‑newsletter, featuring fascinating neuroscience findings and tips, combined with fun brain teasers. #1. To celebrate this quite-challenging Thanksgiving, here are five fun brain teasers that readers have enjoyed the most this year so far. It is always good to learn more about (and appreciate) that most precious resource we all (yes, all) have up there! Five fun brain teasers to thank evolution for our human brains and minds #2. Want more? Ready, Set, Go! A few brain teasers to flex those cognitive muscles #3. “[Breathing techniques] are allowing you to consciousl...
Source: SharpBrains - November 30, 2020 Category: Neuroscience Authors: SharpBrains Tags: Brain Teasers Brain/ Mental Health Education & Lifelong Learning Peak Performance Technology & Innovation anxiety BCI biomarker Breathing cognitive engagement cognitive-reserve disorders doctors EIT European Institute of Innova Source Type: blogs

Five fun brain teasers to thank evolution for our human brains and minds
To celebrate this quite-challenging Thanksgiving, here are five fun brain teasers and games that readers have enjoyed the most this year so far. It is always good to learn more about (and appreciate) that most precious resource we all (yes, all) have up there! #1. First of all, these days it’s always important to test your stress level #2. You say you know the colors? Try the Stroop Test #3. Check out this classic attention experiment #4. What do you know about mental self-rotation? #5. Last but not least, here are ten classic illusions to tease your mind.   Thank you in advance for trying them, enjoying them, a...
Source: SharpBrains - November 25, 2020 Category: Neuroscience Authors: Caroline Latham Tags: Brain Teasers brain games for adults brain teasers for adults brain teasers for teens brain-teaser brain-teaser-games cognitive cognitive-abilities cognitive-ability mind-teasers puzzle games for adults Source Type: blogs

Studies identify key ethical concerns raised by invasive and non-invasive neurotechnologies
Studies outline key ethical questions surrounding brain-computer interface tech (NCSU release): Brain-computer interface (BCI) technologies are no longer hypothetical, yet there are fundamental aspects of the technology that remain unaddressed by both ethicists and policy-makers. Two new papers address these issues by outlining the outstanding ethical issues, offering guidance for addressing those issues, and offering particular insight into the field of BCI tech for cognitive enhancement. “BCI devices can be non-invasive devices that users wear, or they can be invasive devices, which are surgically implanted,”...
Source: SharpBrains - November 23, 2020 Category: Neuroscience Authors: SharpBrains Tags: Peak Performance Technology & Innovation BCI brain-computer interface cognitive cognitive-enhancement ethics Neuroethics Neurotechnology non-invasive neurotechnologies non-invasive neurotechnology Source Type: blogs

Next: Analyzing typing speed, speech and sleep patterns to identify cognitive decline, dementia, Parkinson ’s, and more
AI May Help Identify Patients With Early-Stage Dementia (The Wall Street Journal): Researchers are studying whether artificial-intelligence tools that analyze things like typing speed, sleep patterns and speech can be used to help clinicians better identify patients with early-stage dementia. Huge quantities of data reflecting our ability to think and process information are now widely available, thanks to watches and phones that track movement and heart rate, as well as tablets, computers and virtual assistants such as Amazon Echo that can record the way we type, search the internet and pay bills… The goal of using...
Source: SharpBrains - November 19, 2020 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation artificial intelligence brain signatures cognitive decline digital medicine doctors early-stage dementia machine-learning neurocognitive neurodegenerative disorders sleep-patterns speech Source Type: blogs

New book shares science and techniques to breathe better and promote calmness not anxiety
Scrolling social media, amid frantic election-related posts and news of escalating COVID-19 cases, you may have come across a friend reminding everyone to just breathe. But can just-breathing really make a difference? In his new book Breath: The New Science of a Lost Art, journalist James Nestor argues that modern humans have become pretty bad at this most basic act of living. We breathe through our mouths and into our chests, and we do it way too fast. There’s even a phenomenon called “email apnea,” where multitasking office workers breathe irregularly and shallowly, or even hold their breath, for half a...
Source: SharpBrains - November 17, 2020 Category: Neuroscience Authors: Greater Good Science Center Tags: Education & Lifelong Learning anxiety book Breathing breathing techniques email apnea James Nestor meditation mental health mindfulness parasympathetic pranayama yogic breathing Source Type: blogs

FDA grants clearance for NightWare app designed to reduce PTSD-related nightmares
FDA grants De Novo clearance to prescription Apple Watch app for nightmare disorder (MobiHealth News): The FDA granted Minneapolis-based NightWare a De Novo clearance on Friday for its Apple Watch and iPhone app designed to improve the sleep quality of those experiencing nightmare disorder and nightmares related to PTSD. The digital therapeutic – which received breakthrough designation from the agency last year – uses the Watch’s sensors to track the heart rate and movement of users as they sleep. After establishing a baseline profile for the patient within one or two nights’ sleep, the machine lear...
Source: SharpBrains - November 16, 2020 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation Apple Watch De Novo clearance digital therapeutic FDA heart-rate iPhone app machine-learning nightmares NightWare prescription PTSD sleep quality Source Type: blogs

Debate: How should doctors prescribe exercise to ensure compliance and engagement?
Table 2. Neurobiological benefits of exercise. How to Effectively Prescribe Exercise (Psychiatric Times): Exercise can be a useful tool in managing symptoms of anxiety and depression. Learn how you can integrate exercise prescriptions into your treatment plans. While most of us appreciate its importance, we also recognize that avoidance is exceedingly common. Too often patients hear the word exercise and develop an aversive reaction, as they anticipate that it involves intensive training reserved only for the athletically elite. So how can one simply and effectively counsel a patient on exercise to increase their chances o...
Source: SharpBrains - November 12, 2020 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health anxiety depression exercise neurobiological neuroplasticity Neuropsychology Physical-activity stress and coping. Source Type: blogs

Study: Work in adulthood seen to significantly delay memory decline after age 60, supporting the Cognitive Reserve theory
Conclusions: Women who worked for pay in early adulthood and midlife experienced slower rates of later-life memory decline, regardless of marital and parenthood status, suggesting participation in the paid labor force may protect against later-life memory decline. The Study in Context: Study: High Cognitive Reserve (CR) seen to significantly lower dementia risk even in the presence of high Alzheimer’s Disease (AD) neuropathology Build Your Cognitive Reserve: An Interview with Dr. Yaakov Stern Systematic review finds ten lifestyle factors that clearly impact the probability of developing Alzheimer’s disease (A...
Source: SharpBrains - November 10, 2020 Category: Neuroscience Authors: Alvaro Fernandez Tags: Brain/ Mental Health cognitive cognitive-domains cognitive-reserve cognitive-stimulation memory-decline memory-loss paid work social-engagement working Source Type: blogs

Using Reddit as a population-level “mental health tracker” during the COVID pandemic
Conclusions: By using a broad set of NLP techniques and analyzing a baseline of prepandemic posts, we uncovered patterns of how specific mental health problems manifest in language, identified at-risk users, and revealed the distribution of concerns across Reddit, which could help provide better resources to its millions of users. We then demonstrated that textual analysis is sensitive to uncover mental health complaints as they appear in real time, identifying vulnerable groups and alarming themes during COVID-19, and thus may have utility during the ongoing pandemic and other world-changing events such as elections and p...
Source: SharpBrains - November 9, 2020 Category: Neuroscience Authors: SharpBrains Tags: Technology & Innovation Uncategorized anxiety machine-learning mental health natural language processing pandemic Source Type: blogs

A few brain teasers to flex those cognitive muscles over the weekend
Look around you, wherever you are, and find three green things that may fit in your pockets, and three red objects that are clearly too big to fit. Done? OK, now you have six objects. Go ahead and say their names in alpha­bet­i­cal order. Done? Now name them in reverse alphabetical order. Done? Now count the total number of syllables in those six words. Not easy, right? All these mental operations engage your working memory — think of working memory as your temporary mental workspace where you can hold and integrate several units of information at once. Feel free to practice in different locations &hell...
Source: SharpBrains - November 6, 2020 Category: Neuroscience Authors: Caroline Latham Tags: Brain Teasers adults brain games for adults brain teasers for adults brain teasers for teens brain-teaser brain-teaser-games cognitive cognitive-abilities cognitive-ability mental muscles mind-teasers Source Type: blogs

Alphabet ’s X shares Amber EEG system to expand the quest for mental health biomarkers
Amber’s final EEG prototype: Headset, sensor strip and bioamp Alphabet’s X details Project Amber, a quest for a single biomarker for depression that fell short of its goal (TechCrunch): Alphabet’s X (the Google-owner’s so-called “Moonshot Factory”) published a new blog post today about Project Amber, a project it’s been working on over the past three years — the results of which it’s now making available open source for the rest of the mental health research community to learn from, and hopefully build upon. The X project sought to identify a specific biomarker for depr...
Source: SharpBrains - November 5, 2020 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation Alphabet biomarker depression digital phenotyping EEG electroencephalography machine-learning med-tech mental health research Moonshot Factory open-source predictive Project Amber Source Type: blogs

To call, or to text, that is the (mental well-being) question
Like most people, I’ve been doing a lot of texting with friends and family lately. COVID-19 (and the physical separation it necessitates) has made socializing in person very limited, which means I’ve had to work harder than ever to keep my relationships strong and healthy. But a new study suggests that if that’s my aim, texting may not be enough. To stay close at a time when we all need companionship and support, we’d be better off picking up the phone or setting up a video call—doing something where we can actually hear another person’s voice. In the study, participants imagined having ...
Source: SharpBrains - November 3, 2020 Category: Neuroscience Authors: Greater Good Science Center Tags: Brain/ Mental Health call mental well being text well-being Source Type: blogs