Study: Higher mental wellbeing (in 2016) seen to lower healthcare costs (in 2017)
Conclusions: Estimated reductions in costs related to mental well-being add to what is already known about potential savings related to the prevention of mental illness. It does so by illustrating the savings that could be made by moving from lower to higher levels of mental well-being both within and beyond the clinical range. Our estimates pertain to costs associated with those health-related outcomes that were included in the study, but excluding other social and economic outcomes and benefits. They cover immediate cost estimates (costs generated the year following mental well-being measurement) and not those that could...
Source: SharpBrains - May 7, 2021 Category: Neuroscience Authors: The Conversation Tags: Brain/ Mental Health continuum mental health promotion mental wellbeing mindfulness self care Source Type: blogs

Cumulus Neuroscience raises $8.3M to develop EEG-based wireless ‘Fitbit for the brain’
Belfast-based Cumulus raises €6.9m for its ‘Fitbit for the brain’ (The Irish Times): … Formerly known as BrainWaveBank, the company has developed a wireless electroencephalogram (EEG) headset and proprietary software platform that use advanced analytics and machine learning to measure cognitive fitness. “This funding will allow us to build on the ground-breaking advances we have made in remote, frequent monitoring of brain activity and cognitive function in the home, in partnership with leading developers of digital biomarkers,” said Mr Cunningham, the company’s chief executive. &l...
Source: SharpBrains - May 5, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation Alzheimer’s Disease BrainWaveBank clinical-trials CNS CNS therapies cognitive-fitness Cumulus Neuroscience dementia Dementia Discovery Fund digital biomarkers EEG electroencephalogra Source Type: blogs

Reading Our Minds: New book issues strong call to action to modernize psychiatry
The Rise of Big Data Psychiatry (The Wall Street Journal): As a physician, I need to figure out three things when a new patient walks into my office: what their life is typically like, what has changed that made them seek treatment and what I can do to help them. It’s a complex problem, and most fields of medicine approach it by taking measurements. If I were a cardiologist evaluating a patient’s chest pain, for instance, I would speak with the patient, but then I would listen to their heart and measure their pulse and blood pressure. I might order an electrocardiogram or a cardiac stress test, tools that weren...
Source: SharpBrains - May 4, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation big data Big Data Psychiatry clinical decision tools machine-learning neural networks neurotechnologies Neurotechnology suicidal thoughts Twitter Source Type: blogs

On centenarians, memory, Mars, tDCS, ADHD, digital health, beautiful brains, and more
Hendrikje van Andel Schipper (1890–2005) Welcome to a new edition of SharpBrains’ e‑newsletter, featuring ten timely resources and research findings for lifelong brain and mental fitness. #1. Let’s start with a fascinating story and study 🙂 Study with 330 centenarians finds that cognitive decline is not inevitable … (Henne Holstege, PhD, assistant professor at Amsterdam University Medical Center) said her interest in researching aging and cognitive health was inspired by the “fascinating” story of Hendrikje van Andel Schipper, who died at age 115 in 2005 “completely cogn...
Source: SharpBrains - April 30, 2021 Category: Neuroscience Authors: SharpBrains Tags: Attention & ADD/ADHD Brain/ Mental Health Education & Lifelong Learning Technology & Innovation ADHD-Treatment aging Alzheimer’s astronauts beautiful brains brain health centenarians cognitive decline cognitive-function cogniti Source Type: blogs

Let ’s welcome Mental Health Month (May) by appreciating our beautiful brains
Self Reflected was created over two years by a team that included neuroscientists, engineers, physicists, and students, and is a hyperdetailed representation of 500,000 neurons in a sagittal slice. Credit: Greg Dunn and Brian Edwards. Between Thought and Expression (Cerebrum): Greg Dunn was on his way to a Ph.D. in neuroscience at the University of Pennsylvania when he realized that bringing the brain’s beauty to life was a more suitable role for him than lab work. He started in ink, inspired by Chinese, Japanese, and Korean paintings and the similarities he found in the microscopic world of neurons and the macroscop...
Source: SharpBrains - April 28, 2021 Category: Neuroscience Authors: SharpBrains Tags: Education & Lifelong Learning beauty Mental Health Month Microetchings neuro art neuroimaging Neurons neuroscience Neurotechnology Source Type: blogs

Ohio joins Indiana and Kentucky in funding Pear Therapeutics ’ digital addiction treatments
Ohio is third state to fund Pear’s digital therapeutics to tackle addiction (pharmaforum): The company has been pushing for more reimbursement of its three marketed DTx products in the US following a first FDA approval in 2017. Pear said that the Ohio Department of Mental Health and Addiction Services (OhioMHAS) and RecoveryOhio are providing access to Pear’s FDA-approved DTx reSET and reSET‑O, for treatment of substance use disorder and opioid use disorders, respectively. Funding is provided by the State Opioid Response (SOR) 2.0 grant, administered by OhioMHAS, and part of the US Department of Health and Hu...
Source: SharpBrains - April 26, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation addiction cognitive-behavioral-therapy digital therapeutics FDA Indiana Kentucky Ohio opioid use disorder Pear Therapeutics prescription digital therapeutics reSET reSET-O substance Source Type: blogs

Shape your environment, shape your mind
One of the biggest contributors to our happiness is something we barely pay attention to: the voice inside our own heads. As psychologist Ethan Kross describes in his new book Chatter, that voice is constantly analyzing the situations we’re in, reflecting on the past and future, and telling us who we are. While sometimes friendly and optimistic—it’s OK, everything’s going to work out!—it can also be critical and downbeat. Our inner voice can berate us for mistakes or decide our life is ruined. It can ruminate on negative emotions and experiences, dredging them up without any kind of constructi...
Source: SharpBrains - April 23, 2021 Category: Neuroscience Authors: Greater Good Science Center Tags: Education & Lifelong Learning book brain calmer mind chatter clutter declutter environment Ethan Kross feelings nature rumination thoughts Source Type: blogs

Next in NASA ’s path to Mars: Overcoming astronauts’ cognitive and mental health challenges
– Illustration by Zoë Van Dijk Space Between the Ears (Cerebrum): A few short months ago, news programs around the globe showed NASA engineers and scientists celebrating as a robot named Perseverance successfully landed on the surface of Mars. The mission: capture and share images and audio that have never been seen or heard before. As impressed as most observers were of this major milestone, many couldn’t help but wonder when we might be ready to someday send humans. While it seems the stuff of science fiction and almost inconceivable, the answer—according to recent NASA planning—is before the...
Source: SharpBrains - April 21, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Peak Performance Artemis astronauts brain-function brain-teaser cognitive cognitive-performance Gateway MaRS mental capacities mental health challenges NASA spaceflight Stress stressors Source Type: blogs

Study: Depression affects visual perception … making it more accurate
The brightness of Figures A and B is exactly the same, but they are perceived differently due to a difference in the background. This illusion was perceived similarly by the patients and healthy control subjects. The contrast of Figures C and D is exactly the same as well, but the perception of this illusion was weaker among the depressed patients than the control subjects. (Salmela et al, J. Psychiatry Neurosci, 2021) Depression affects visual perception (press release by University of Helsinki): Researchers specialised in psychiatry and psychology at the University of Helsinki investigated the effects of depression on vi...
Source: SharpBrains - April 19, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Education & Lifelong Learning behavioural tests Cerebral Cortex cortical processing depression electrophysiology perception tests psychiatry Psychology visual-perception Source Type: blogs

Emerging applications of transcranial Direct Current Stimulation (tDCS): e ‑sports skills training, cognitive enhancement in older adults
10 Minutes of Electrical Stimulation During Gaming Helps Improve e‑Sports Skills (Technology Networks): Researchers at Lero, the Science Foundation Ireland Research Centre for Software and University of Limerick (UL), have found video gamers can significantly improve their esport skills by training for just 10 minutes a day. The research team at Lero’s Esports Science Research Lab (ESRL) at UL also found novice gamers benefited most when they wore a custom headset delivering transcranial Direct Current Stimulation (tDCS) for 20 minutes before training sessions. Participants wore a custom headset (HALO Neuroscience&...
Source: SharpBrains - April 16, 2021 Category: Neuroscience Authors: SharpBrains Tags: Peak Performance Technology & Innovation cognitive-enhancement cognitive-performance Cognitive-Training e-sports electrical stimulation Gaming Halo Neuroscience healthy older adults Lero tDCS Transcranial-direct-current-stimulation Source Type: blogs

Does ADHD treatment enable long-term academic success? (Yes, especially when pharmacological and non-pharma treatments are combined)
Academic difficulties are one of the most important adverse consequences of ADHD, and they frequently contribute to parents’ decision to seek treatment for their child. Whether treatment consistently yields a positive impact on long-term academic success is thus an important issue; however, the answer to this question has been somewhat controversial. A study published recently in the Journal of Attention Disorders, Long-term outcomes of ADHD: Academic achievement and academic performance, represents the most comprehensive effort to date to identify and synthesize research related to this important question. The Study...
Source: SharpBrains - April 14, 2021 Category: Neuroscience Authors: Dr. David Rabiner Tags: Attention & ADD/ADHD Brain/ Mental Health academic difficulties AD/HD-treatments long-term academic success non-pharmacological Source Type: blogs

Study with 330 centenarians finds that cognitive decline is not inevitable
Hendrikje van Andel Schipper (1890–2005) Age-Related Cognitive Decline May Not Be Inevitable (WebMD): It is often assumed that a decrease in memory and brain function are inevitable parts of aging, but a new study of centenarians suggests otherwise. Investigators found that despite the presence of neurological issues generally associated with Alzheimer’s disease (AD), many centenarians maintained high levels of cognitive performance. (Henne Holstege, PhD, assistant professor at Amsterdam University Medical Center) said her interest in researching aging and cognitive health was inspired by the “fascinating...
Source: SharpBrains - April 13, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Education & Lifelong Learning aging assessments brain resilience brain-reserve centenarians cognitive decline cognitive resilience cognitive trajectories cognitive-performance cognitive-reserve Mini-Mental Stat Source Type: blogs

Final 3 weeks to nominate teachers for the $1M Global Teacher Prize 2021
Dear friends, We hope you are doing well. There is now less than one month to go until applications and nominations close for the Global Teacher Prize, and we wanted to ask you to help us spread the word. We are now starting the seventh cycle of this prize, which continues to highlight the important work of extraordinary teachers around the world. Now more than ever, it is important they are recognised for their contribution and have a seat at the table when decisions are made on education. Teachers applying for the Global Teacher Prize will be assessed on teaching practices, how they innovate to address local challenges, ...
Source: SharpBrains - April 8, 2021 Category: Neuroscience Authors: The Varkey Foundation Tags: Education & Lifelong Learning Global Teacher Prize Lifelong-learning teachers Varkey Foundation Source Type: blogs

From digital therapeutics to personalized mental health solutions: Pear Therapeutics expands platform via partnerships with Empatica, etectRx, KeyWise, and Winterlight
Pear Therapeutics Expands Platform with Digital Biomarkers, Machine Learning Algorithms and Sensor-Based Technologies (press release): Pear Therapeutics, Inc. announced today that it has entered into agreements with multiple technology companies, including Empatica Inc., etectRx, Inc., and KeyWise, Inc. The new technologies complement the voice-based biomarkers previously licensed from Winterlight Labs. These new agreements bolster Pear’s Prescription Digital Therapeutics (PDT) platform, by adding to its library of digital biomarkers, machine learning algorithms, sensor-based technologies, and digital therapeutics. T...
Source: SharpBrains - April 7, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation digital biomarkers digital therapeutics Empatica etectRx KeyWise Pear Therapeutics WinterLight Labs Source Type: blogs

Neuroscientist Lisa Genova, author of the beautiful novel Still Alice, releases non-fiction book on Memory
A Neuroscientist’s Poignant Study of How We Forget Most Things in Life (The New Yorker): Any study of memory is, in the main, a study of its frailty. In “Remember,” an engrossing survey of the latest research, Lisa Genova explains that a healthy brain quickly forgets most of what passes into conscious awareness. The fragments of experience that do get encoded into long-term memory are then subject to “creative editing.” To remember an event is to reimagine it; in the reimagining, we inadvertently introduce new information, often colored by our current emotional state. A dream, a suggestion, an...
Source: SharpBrains - April 5, 2021 Category: Neuroscience Authors: SharpBrains Tags: Education & Lifelong Learning book healthy-brain long-term-memory neuroscientist non-fiction book remember Source Type: blogs

On Awe, Wonder, Biofeedback, CBSM, Virtual Reality, Privacy, Being Wrong, and more
Welcome to a new edition of SharpBrains’ e‑newsletter, this time featuring eleven timely resources and research findings for lifelong brain health and mental well-being. #1. “Awe is the feeling we experience when encountering vast things that we don’t understand. Around the world and in culturally varying ways, studies show, we experience awe in response to others’ kindness and courage, nature, music, religious or spiritual practice, the visual and dramatic arts, and epiphany … It leads us to share, collaborate, and wonder. In experiences of awe, people often speak as if they have found the...
Source: SharpBrains - March 31, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Education & Lifelong Learning Peak Performance Technology & Innovation Applied Neuroscience AppliedVR awe biofeedback Blue Note Therapeutics CBSM consumer-reports digital health Happify Health heart-rate-vari Source Type: blogs

Growing research supports Heart Rate Variability (HRV) biofeedback training to lower stress and anxiety, increase sports performance
Conclusions: HRV biofeedback training is associated with a large reduction in self-reported stress and anxiety. Although more well-controlled studies are needed, this intervention offers a promising approach for treating stress and anxiety with wearable devices. Effect of Heart Rate Variability Biofeedback on Sport Performance, a Systematic Review (Applied Psychophysiology and Biofeedback ) Abstract: Aim is to determine if the training with heart rate variability biofeedback allows to improve performance in athletes of different disciplines. Methods such as database search … All studies had a small sample size (ra...
Source: SharpBrains - March 29, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Peak Performance Technology & Innovation ambulatory monitoring anxiety athletic performance athletic training biofeedback biofeedback training exercise heart-rate-variability HRV lower anxiety lower stress Source Type: blogs

To prevent “cognitive entrenchment,” think like a scientist and be wrong often
In a rapidly changing world, it’s important to be able to adapt and change rather than stubbornly adhering to old ideas and opinions. This was one of the lessons of 2020, a year that forced us to question many of our assumptions about what behaviors are safe, how work and school can be conducted, and how we connect with others. “In a changing world, you have to be willing and able to change your mind. Otherwise, your expertise can fail, your opinions get out of date, and your ideas fall flat,” says organizational psychologist Adam Grant, author of the new book Think Again: The Power of Knowing What You Do...
Source: SharpBrains - March 25, 2021 Category: Neuroscience Authors: Greater Good Science Center Tags: Education & Lifelong Learning Adam Grant book cognitive cognitive entrenchment knowing Think Again Source Type: blogs

AppliedVR raises $29M to help make virtual reality the standard of care for treating chronic pain
AppliedVR Raises $29 Million for Immersive Headsets (LA Business Journal): Century City-based AppliedVR, Inc. announced March 23 that it has raised $29 million in Series A funding that will be used to continue development of an immersive headset to help patients with chronic pain. … The company is building a headset called EaseVRx that will display immersive environments like campfires, mountains and other animated nature scenes to help patients dealing with chronic pain, including fibromyalgia and chronic intractable lower back pain… AppliedVR Chief Executive and co-founder Matthew Stoudt said that the ...
Source: SharpBrains - March 24, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation AppliedVR chronic pain cognitive behavioral therapies FDA fibromyalgia headset mindfulness exercises pain treatment virtual-reality Source Type: blogs

Tip for digital health start-ups: To navigate regulatory gray areas, “engage early and engage often” with the FDA
FDA’s enforcement discretion for digital health is more ambiguous than ever in 2021 (MobiHealthNews): The digital health ecosystem has swelled to encompass a broad range of products over the years. On one end of the spectrum is software-as-medical-devices (SaMD) and prescription digital therapeutics, product categories for which a comprehensive regulatory strategy and engagement with the FDA are mandatory. On the other are wellness apps and other low-risk digital tools that likely spend more time worrying about oversight from the Federal Trade Commission than the health regulator. However, a growing number of compani...
Source: SharpBrains - March 22, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation 510(k) clearance artificial intelligence digital health enforcement discretion FDA Federal Trade Commission SaMD software-as-medical-devices wellness apps Source Type: blogs

Innovation in COVID times: Otsuka and Click Therapeutics announce fully virtual clinical trial, leveraging Verily ’s Project Baseline
Otsuka launches pivotal trial of digital therapeutics for depression (MedCity News): Otsuka Pharmaceutical is launching a virtual study to see if digital therapeutics can reduce depression symptoms. It’s the next step in a partnership between the Tokyo-based drugmaker and Click Therapeutics, a digital health startup that is developing programs for smoking cessation, depression and insomnia. They plan to enroll up to 540 patients in a randomized, controlled trial that will test the digital therapeutic’s efficacy in patients that are taking antidepressants. The remote trial will be conducted using Verily’s ...
Source: SharpBrains - March 19, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation Alphabet antidepressants Click Therapeutics COVID-19 depression digital health Otsuka Project Baseline Verily Source Type: blogs

Happify Health raises $73M to deepen partnerships with pharmaceutical companies and insurance payers
Happify Health raises $73M to expand its digital therapeutic care delivery capabilities (MobiHealth News): Founded in 2012, Happify is best known for digital programs that provided automated self-guided support across various areas of mental health and wellness, such as stress management for employees or health plan members. Should the user need additional support, the platform can also facilitate a referral to third-party coaching, therapy, telemedicine or other available resources. In more recent years the platform has expanded to address more than a dozen other chronic conditions, such as heart health and psoriasis, tha...
Source: SharpBrains - March 17, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation artificial intelligence digital therapeutic solutions digital therapeutics Happify Happify Health mental-wellness pharmaceutical stress-management Source Type: blogs

Five brain teasers to celebrate Brain Awareness Week 2021
Brain Awareness Week 2021 just started. Let’s celebrate by challenging our minds with a few fun brain teasers and illusions 🙂 Here’s a selection of five stimulating brain teasers that readers enjoyed the most so far in 2021: Where’s the baby? And a couple other surprising illusions Please complete these proverbs to exercise your brain in familiar and novel ways Can you connect these pairs of words? Ready to test your stress level? Which way is the bus heading? About Brain Awareness Week: Every March, Brain Awareness Week (BAW) unites the efforts of partner organizations worldwide in a celebratio...
Source: SharpBrains - March 16, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain Teasers brain-awareness-week cognitive-skills illusions Source Type: blogs

How Wonder and Awe help us transcend self, regulate stress, and improve well-being
What is awe? We have all experienced it, even if we didn’t know what to call it. Whether we’re overlooking a beautiful view after a challenging hike or watching a new leaf grow on the plant we’ve been nurturing in lockdown, the feeling we get in that moment—amazed, inspired, transported—is what researchers call awe. In his new book, Awestruck, psychologist Jonah Paquette explains the process underlying the experience of awe and uncovers both its complexity and its value to our well-being. Walking readers through various scientific findings, he shows that awe helps improve our relationships, de...
Source: SharpBrains - March 10, 2021 Category: Neuroscience Authors: Greater Good Science Center Tags: Education & Lifelong Learning awe Awestruck be happier book decrease stress Jonah Paquette positive emotions stress-levels Source Type: blogs

Blue Note Therapeutics raises $26M to help treat cancer-related distress via cognitive behavioral stress management (CBSM)
Blue Note Therapeutics Raises $26.25 Million in Series A Financing (press release): Blue Note Therapeutics, Inc., today announced the closing of a Series A financing round of $26.25 million. Proceeds will allow the company to scale the organization and fund near-term clinical trials of its lead prescription digital therapeutic (PDT), which will potentially improve the treatment of cancer. The capital will also support the development of Blue Note’s pipeline assets. The Series A financing was led by JAZZ Venture Partners and joined by Summer VC. Blue Note Therapeutics is dedicated to serving patients suffering from ca...
Source: SharpBrains - March 9, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation anxiety Blue Note Therapeutics cancer-related distress cancer-treatment depression digital therapeutic Jazz Venture Partners medical devices prescription digital therapeutic psychosocial n Source Type: blogs

Consumer Reports finds unclear, questionable privacy practices and policies among popular mental health apps
Conclusion: Mental health apps show many of the same patterns we see elsewhere in data-collecting apps. However, the sensitivity of the data they collect means the privacy practices and policies are even more important—especially during a pandemic where people are relying on these services in greater numbers for the first time. Our evaluation shows how there are multiple ways to evaluate how thoughtfully mental health apps handle user data collection, management, and sharing to third parties. We call for all apps to improve on the recommendations highlighted in Section 5—adhere to platform guidelines, institute...
Source: SharpBrains - March 4, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation 7 Cups BetterHelp consumer-reports ethics mental health apps MindDoc (formerly known as Moodpath) Neurotechnology privacy Sanity & Self Talkspace Wysa Youper Source Type: blogs

How Pixar ’s “Soul” met the Science of Awe
Five years ago, I (Dacher) received a call from Pixar writer and director Pete Docter to talk about his new film. The last time I said yes to such a request, I served as a scientific consultant for his film Inside Out. So, I was intrigued. Before my visit, Pete offered a brief sketch of the film. The main character, Joe, is a middle-aged jazz pianist in a rut as a middle school band teacher in Queens. Just before his breakthrough show with a famous quartet, he falls into a manhole and dies, entering into another realm of consciousness. There he encounters “The Great Beyond”—but escapes to a pre-life realm...
Source: SharpBrains - March 2, 2021 Category: Neuroscience Authors: Greater Good Science Center Tags: Education & Lifelong Learning art awe connection creativity mental states Pixar purpose science soul Source Type: blogs

On Brain Awareness Week, mental health innovation, tDCS, biofeedback, psychedelics, and more
Welcome to a new edition of SharpBrains’ e‑newsletter, starting with some ideas to get in the mood for Brain Awareness Week next month (March 15–21st). May BAW 2021 be a hundred times more upbeat than last year’s… #1. Seven brain teasers and a neuroplasticity podcast to celebrate Brain Awareness Week 2021 #2. Imagine what this capability may mean just a few years from now. Should/ will Google alert Gmail users about their (future) cognitive status? Study: Artificial intelligence program identifies linguistic markers that predict, with 70% accuracy, who gets Alzheimer’s Disease years la...
Source: SharpBrains - February 26, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health SharpBrains Monthly eNewsletter Technology & Innovation behavioral biofeedback Brain Teasers cognitive Halo Neuroscience Humanest Care Koa Health mental healthcare Mightier Modern Health neuroplasticity psy Source Type: blogs

Four trends accelerating mental health innovation in the COVID/ post-COVID era
The money behind mental health: How the pandemic increased innovation, investment in behavioral health care (Fierce Healthcare): Earlier this month, Modern Health marked a milestone few companies ever reach: unicorn status. With the help of its latest $74 million funding round, the startup, which serves as a mental health benefits platform for employers, topped a $1 billion valuation. … And while Modern Health was already attracting plenty of interest before the pandemic, CEO Alyson Watson said her company is among those in the behavioral health space that have seen what can only be described as a seismic shift acro...
Source: SharpBrains - February 24, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation Behavioral Health COVID-19 digital behavioral health employers mental health benefits mental health innovation Modern Health Source Type: blogs

Growing research points to expanding adoption of online cognitive behavioral therapies, both guided and unguided
We are seeing a number of fascinating meta-analyses comparing the value of A) face-to-face vs. Internet-based cognitive behavioral therapies and B) guided vs unguided internet-based cognitive behavioral therapy, especially in the case of depression. Here you have a couple great examples, suggesting a growing adoption in the near future of web-based, and increasingly personalized, interventions. A) A comparison of electronically-delivered and face to face cognitive behavioural therapies in depressive disorders: A systematic review and meta-analysis (Eclinical Medicine). From the Abstract: Background: Cognitive behavioural ...
Source: SharpBrains - February 22, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation CBT cognitive behavioral therapies depression eCBT Internet-based cognitive behavioral therapies Source Type: blogs

Neuromodulation developer Halo Neuroscience closes its doors; Flow Neuroscience acquires assets
Flow acquires brain stimulation technology developer Halo (Medical Device Network): Flow Neuroscience has acquired the assets of brain stimulation technology developer Halo Neuroscience to advance its research into depression and other mental health disorder treatments. The financial details of the deal have not been disclosed. Using Halo’s research in neuromodulation field, Flow Neuroscience plans to enhance its current medically certified tDCS headset for depression … A form of neuromodulation, tDCS uses constant, low direct current delivered via electrodes on the head. In July 2019, Flow announced that it r...
Source: SharpBrains - February 19, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Peak Performance Technology & Innovation brain stimulation depression Flow Neuroscience Halo Neuroscience headset neuromodulation tDCS Transcranial-direct-current-stimulation Source Type: blogs

Seven brain teasers and a neuroplasticity podcast to celebrate Brain Awareness Week 2021
Brain Awareness Week 2021 takes place next month. Why not start celebrating now by challenging our minds and discussing the latest about lifelong neuroplasticity? Here’s a selection of seven stimulating brain teasers that readers enjoyed the most in 2020: Please consider Linda’s job prospects Explore your perceptual biases Think outside the box with a few fun riddles Complete these proverbs and exercise your memory and reasoning Where do words go? Test your stress level if you dare… Which way is the bus heading? And here’s the podcast where Eric White interviews our very own Alvaro Fernandez...
Source: SharpBrains - February 17, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain Teasers Brain/ Mental Health Education & Lifelong Learning brain-awareness-week Lifelong Neuroplasticity podcast Source Type: blogs

Digital mental health start-up Koa Health raises €30M to accelerate growth in Europe and the US
Mental healthcare startup Koa Health closes €30M Series A funding to expand its international footprint (Silicon Canals): In a recent development, Barcelona-based digital mental healthcare provider, Koa Health, has announced it closed an oversubscribed €30M Series A funding round … The company had raised the funds back in October 2020 and had also announced its spin-out from Alpha, Telefónica’s startup factory. The raised capital will be used to boost Koa Health’s growth and expand its international footprint including the US. Oliver Harrison, CEO of Koa Health says, “We know ...
Source: SharpBrains - February 16, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation Alpha digital mental health Koa Health mental healthcare Oliver Harrison startup Telefónica Source Type: blogs

Survey finds concerns AND hope to address growing mental health needs due to the covid pandemic
This study provides proof-of-concept of the viability for researchers and private companies to work collaboratively toward a common good. Digital services providers reported a diverse range of mental health concerns. A recurring observation is that demand for digital mental health support has risen, and that the nature of this demand has also changed since COVID-19, with an apparent increased presentation of anxiety and loneliness. News in Context: Three ways to protect your mental health during –and after– COVID-19 The landscape of digital mental health apps: huge unmet needs, quality concerns, app stores as...
Source: SharpBrains - February 11, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation anxiety COVID-19 digital health digital mental health Humanest Care loneliness mental health apps Mental Health Tsunami mental healthcare ORCHA Source Type: blogs

Can biofeedback-based videogames help children better manage stress? Magellan Health and Mightier secure $2 million NIMH grant to investigate
This study’s goal is to validate that digital tools like Mightier can improve health outcomes, lower the cost of care and increase access to mental healthcare” said Matthew Miller, senior vice president, behavioral health, Magellan Healthcare. About the grant: The research is supported by the National Institute Of Mental Health of the National Institutes of Health under Award Number R44MH124574. The NIMH supports scientists, clinicians, and research personnel at universities, medical schools, hospitals, small businesses, and other institutions via grants, contracts, and cooperative agreements. Researchers at NI...
Source: SharpBrains - February 10, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation Behavioral Health biofeedback biofeedback video game heart rate-monitor Magellan Health mental health disorders Mightier NIMH regulate stress video-games videogame wearable Source Type: blogs

The landscape of digital mental health apps: huge unmet needs, quality concerns, app stores asked to ensure transparency
Addressing the mental health crisis (Pharma Field): Each day we find out more about the mental health effects of the pandemic. Early on, the Office for National Statistics found that one in five Britons reported symptoms of depression, compared with one in 10 before. And, according to a recent study led by the University of Nottingham and King’s College London, stress, anxiety and depression were all significantly higher in participants compared with ‘population norms’, with 64% of the participants reporting symptoms of depression and 57% reporting symptoms of anxiety. … Through simple force of nec...
Source: SharpBrains - February 5, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation advertising standards cognitive behavioural therapy consumer protection digital health digital health applications digital mental health digital mental health interventions digital therapeutic Source Type: blogs

Next: Psychedelic-assisted psychotherapy?
How ecstasy and psilocybin are shaking up psychiatry (Nature): … The Imperial study was one of a spate of clinical trials launched over the past few years using illicit psychedelic drugs such as psilocybin, lysergic acid diethylamide (LSD) and MDMA (3,4‑methylenedioxymethamphetamine, also known as molly or ecstasy) to treat mental-health disorders, generally with the close guidance of a psychiatrist or psychotherapist. The idea has been around for decades — or centuries in some cultures — but the momentum has picked up drastically over the past few years as investors and scientists have begun to champi...
Source: SharpBrains - February 4, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Books lysergic acid diethylamide MDMA mental health disorders psilocybin psychedelic psychiatrist psychotherapist Psychotherapy Source Type: blogs

Study: Artificial intelligence program identifies linguistic markers that predict, with 70% accuracy, who gets Alzheimer ’s Disease years later
Fig. 3. Cookie-theft picture description task (CTT) examples from the Framingham Heart Study, including an unimpaired sample (a), an impaired sample (b), and an even more impaired sample showing significant misspellings and minimal grammatic complexity ©. Credit: Eyigoz et al (2020) Alzheimer’s Prediction May Be Found in Writing Tests (The New York Times): … the researchers looked at a group of 80 men and women in their 80s — half had Alzheimer’s and the others did not. But, seven and a half years earlier, all had been cognitively normal. The men and women were participants in the Framingham H...
Source: SharpBrains - February 3, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation Alzheimers-disease artificial intelligence biomarker clinical-diagnosis cognitive decline Cognitive-tests cognitively dementia Framingham Heart Study impairment linguistic analysis MCI Source Type: blogs

The latest on brain health, neurotechnology, artificial intelligence and “never stop wondering”
Welcome to a new edition of SharpBrains’ e‑newsletter, featuring a life well lived, the latest news on brain health and innovation, and some brain teasers in honor of International Brain Teaser Month. #1. Thank you, Sharon. We won’t. “Never stop wondering” — Sharon Begley, science journalist, RIP #2. Write injuries in sand, kindnesses in ____________. Milk the cow, but do not pull off the ___________. Enjoy these 5 US and 7 international proverbs to test your cognitive skills. #3. Beware the snakes as you tease your mind with this optical illusion. #4. The blood-brain barrier is hopefully ha...
Source: SharpBrains - January 29, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation artificial intelligence brain health Brain Teasers brain-teaser cognitive neurocognitive Neurotechnology Source Type: blogs

If you ’re a fruit fly, tease your mind with this optical illusion. Humans welcome too.
This study shows how illusions can provide insight into visual processing mechanisms and principles across phyla. More fun illusions and brain teasers: Three quick brain teaser games to test your perceptual and cognitive skills Test your Brain with these 10 Visual Illusions Top 25 fun Brain Teasers and Puzzles 12 fun riddles to welcome a sharp new year What are cognitive abilities and how to boost them? The post If you’re a fruit fly, tease your mind with this optical illusion. Humans welcome too. first appeared on SharpBrains. (Source: SharpBrains)
Source: SharpBrains - January 26, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain Teasers cognitive cognitive-skills optical illusion optical-illusions perception rotating snake illusion visual-perception Source Type: blogs

FDA releases first Artificial Intelligence (AI) regulatory plan to promote responsible digital health innovation
FDA Releases Artificial Intelligence/Machine Learning Action Plan (FDA press release): Today, the U.S. Food and Drug Administration released the agency’s first Artificial Intelligence/Machine Learning (AI/ML)-Based Software as a Medical Device (SaMD) Action Plan. This action plan describes a multi-pronged approach to advance the Agency’s oversight of AI/ML-based medical software … The AI/ML-Based Software as a Medical Device Action Plan outlines five actions that the FDA intends to take, including: Further developing the proposed regulatory framework, including through issuance of draft guidance on a pr...
Source: SharpBrains - January 25, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation artificial intelligence digital health digital health innovation FDA Food and Drug Administration machine-learning regulatory framework software Source Type: blogs

Study: Wearable sensors and machine learning may well (one day) help detect a broad range of epileptic seizures
Conclusion: Automatic epileptic seizure detection using machine learning and wearables data is feasible. Preliminary results show better-than-chance seizure detection across a broad range of epileptic seizures. Future improvements may consider clinical chrono-epileptological variables, such as seizure duration, semiology, and etiology or syndrome, and alternative data balancing, pre- and post-processing, fusion and ensemble learning methods. Thus, while findings suggest feasibility, performance following future adjustments may improve further. News in Context: Special Issue: Seizure detection and mobile health devices in...
Source: SharpBrains - January 22, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation acceptability deep learning EEG epilepsy mHealth seizure detection wearables Source Type: blogs

“Never stop wondering” — Sharon Begley, science journalist, RIP
This article was adapted by arrangement with Hudson Street Press, a member of Penguin Group (USA) Inc., from The Emotional Life of Your Brain: How Its Unique Patterns Affect the Way You Think, Feel, and Live–and How You Can Change Them by Richard J. Davidson, Ph.D., and Sharon Begley. Copyright by Richard J. Davidson, Ph.D., and Sharon Begley.The post “Never stop wondering” — Sharon Begley, science journalist, RIP first appeared on SharpBrains. (Source: SharpBrains)
Source: SharpBrains - January 21, 2021 Category: Neuroscience Authors: Alvaro Fernandez Tags: Education & Lifelong Learning books on brain brain-functions Courtney Nobile emotional style Emotions neuroplasticity relationships Resiliency Richard-Davidson Sharon-Begley Source Type: blogs

Can COVID-19 coronavirus “invade” human brain tissue? (Quick answer: evidence so far is mixed)
Brain scans show lower part of a COVID-19 patient’s brain stem, postmortem. Arrows point to light and dark spots suggesting blood vessel damage, without signs of infection by the coronavirus that causes COVID-19. Credit: National Institute of Neurological Disorders and Stroke, NIH Taking a Closer Look at COVID-19’s Effects on the Brain (NIH Director’s blog): While primarily a respiratory disease, COVID-19 can also lead to neurological problems. The first of these symptoms might be the loss of smell and taste, while some people also may later battle headaches, debilitating fatigue, and trouble thinking cle...
Source: SharpBrains - January 19, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health brain fog brain tissue brainstem COVID-19 human-brain neurological neurological problems Neurons NIH Source Type: blogs

Neuroimaging, big data and mental health: A survey of the land
This figure shows how different brain networks function together; the lines measuring the strength of communication among various networks. By using such displays, we can evaluate what is called the human functional connectome—and also how mental illness is disrupted. [Figure courtesy of Vince Calhoun] Mental and degenerative disorders are among the most costly and common causes of disability in society today. Because the brain is the most complex organ in the human body, diagnosing and treating problems when things go wrong poses enormous challenges. Even before the 1990s was designated the Decade of the Brain, the ...
Source: SharpBrains - January 15, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation artificial intelligence brain-machine interface degenerative disorders neuroimaging psychiatry virtual-reality Source Type: blogs

Neurostimulation device GammaSense by Cognito Therapeutics secures FDA Breakthrough Device Designation to explore Alzheimer ’s Disease applications
Credit: The Picower Institute @ MIT Cognito Therapeutics nets FDA breakthrough label for light, sound therapy for Alzheimer’s disease (Fierce Biotech): Using specific frequencies of flashing lights and sounds to stimulate the brain’s electrical activity, Cognito Therapeutics believes it can help treat Alzheimer’s disease by energizing neurons and reactivating the immune system. Described as similar to a strobe light, but much faster, Cognito’s GammaSense stimulation system is built into a pair of opaque glasses worn with a set of headphones. The daily treatment has shown positive effects in mice, w...
Source: SharpBrains - January 14, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation amyloid plaques breakthrough device breakthrough therapy cognitive-symptoms Cognito Therapeutics digital therapeutics FDA GammaSense hippocampus neurodegenerative-diseases neuromodulatio Source Type: blogs

The new frontier in neurocognitive monitoring and dementia screening: the Apple Watch
Biogen to Launch Pioneering Study to Develop Digital Biomarkers of Cognitive Health Using Apple Watch and iPhone (press release): Biogen Inc. (Nasdaq: BIIB) today announced a new virtual research study, in collaboration with Apple, to investigate the role Apple Watch and iPhone could play in monitoring cognitive performance and screening for decline in cognitive health including mild cognitive impairment (MCI). The multi-year, observational research study will be launched later in 2021 and will enroll participants including young and aging adults with a range of cognitive performance. Driven by the powerful technology in A...
Source: SharpBrains - January 12, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation Apple Biogen cognitive-health detect cognitive impairment detect dementia digital biomarkers iPhone MCI memory-loss mild-cognitive-impairment neurocognitive neuroscience werables Source Type: blogs

Fun brain teaser to test your cognitive skills during International Brain Teaser Month
Memory relies mostly on the temporal lobes (see green area) and also the frontal lobes (red), so those are the areas that will get some good neuronal activation when readers raised in the US try to remember the missing words in the American proverbs below. Now, if you were raised outside the US and are not familiar with those proverbs you will have to use your reasoning skills more than your memory skills — In that case, frontal lobe activation will be wider and more intense. Conversely, if you were raised in the US you will find the international proverbs below to be more challenging. You will not be able to remembe...
Source: SharpBrains - January 8, 2021 Category: Neuroscience Authors: Dr. Pascale Michelon Tags: Brain Teasers brain puzzles for adults Brain-games brain-puzzles brain-teaser-puzzles cognitive-exercise frontal-lobes improve-memory International Brain Teaser Month logic-puzzle logical-skills mind-teasers proverbs puzzle games Source Type: blogs

Machine learning study finds standardized brain scan biomarker to detect depression with 66% accuracy
New Study Brings Biomarkers For Depression Closer To The Clinic (Forbes): Scientists have been studying biological signs of depression in the brain, looking for markers that could be used to identify the disorder. A team of scientists recently developed a technique using machine learning that can identify whether a given patient’s brain scan shows one of depression’s neural signatures… Clinicians currently diagnose major depressive disorder, commonly called depression, based on a patient’s reported symptoms, like changes in mood, activity enjoyment, appetite or sleeping, for example. But people wit...
Source: SharpBrains - January 6, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation brain markers brain-scan clinical applicability depression EEG machine-learning neural signature neural signatures neuroscience Source Type: blogs

Tip: To manage stress, sleep better. To sleep better, keep a good routine and manage stress.
Disrupted routines and worries about coronavirus have made it harder for us to sleep this year. For example, reports suggest there was a 15% increase in prescriptions for sleep medication prescriptions at the beginning of the pandemic in the U.S., and a 37% increase in insomnia in China. Importantly, if you’ve been feeling out of sorts over the past few months, the lack of sleep could be partly to blame. According to new research conducted before the pandemic, sleep deprivation dampens our enthusiasm about positive events, and makes it harder to find the silver linings when we’re under stress. In the paper, pub...
Source: SharpBrains - January 4, 2021 Category: Neuroscience Authors: Greater Good Science Center Tags: Brain/ Mental Health emotionally Emotions improving sleep insomnia psychologically Stress Source Type: blogs