TWiV 666: A far-UVC light bulb went off for David Brenner
David Brenner joins TWiV to explain how far-UVC lights could provide protection from SARS-CoV-2 and other airborne viruses in public places, solutions to face mask fogging, transmission during airplane flights, and listener questions. Click arrow to playDownload TWiV 666 (78 MB .mp3, 129 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv (Source: virology blog)
Source: virology blog - September 25, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology airborne inactivation airplane transmission coronavirus COVID-19 face mask far-UVC fogging pandemic SARS-CoV-2 UV light vaccine viral viruses Source Type: blogs

TWiV 665: This half-week in coronavirology
Daniel Griffin provides a clinical report on COVID-19, superspreading potential of SARS-CoV-2 in Hong Kong, structure of virion glycoprotein of a commmon cold coronavirus reveals changes driven by prolonged circulation in humans, and listener email. Click arrow to playDownload TWiV 665 (106 MB .mp3, 177 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv (Source: virology blog)
Source: virology blog - September 21, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology coronavirus COVID-19 evolution hemagglutinin-esterase HKU1 OC43 pandemic SARS-CoV-2 superspreader viral viruses Source Type: blogs

Trial By Error: More CBT Research from Sir Simon and Professor Chalder, Part 2
By David Tuller, DrPH And now Professor Sir Simon Wessely has popped up again to present more misinformation in a paper produced along with his longtime King’s College London colleague, Professor Trudie Chalder. I wrote about this paper last month, when it appeared in a pre-print version after having been accepted for publication by the […] (Source: virology blog)
Source: virology blog - September 21, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized Source Type: blogs

Superspreaders of SARS-CoV-2
A super spreader is an individual who is more likely to infect others compared with a typical patient (pictured). An example is the doctor who treated early SARS-CoV patients in China, traveled to a hotel in Hong Kong, and infected 10 others who then went on bring the virus to multiple countries. Superspreaders of SARS-CoV-2 […] (Source: virology blog)
Source: virology blog - September 18, 2020 Category: Virology Authors: Vincent Racaniello Tags: Uncategorized COVID-19 dispersion factor pandemic R0 reproduction index SARS-CoV-2 superspreader transmission viral virology virus viruses Source Type: blogs

TWiV 664: TWiV is for the dogs
On this mid-week edition, does it matter that SARS-CoV-2 is mutating, seasonal coronavirus immunity is short-lived, another bogus claim that the virus was produced in a laboratory (it came from Nature), and answers to listener questions. Click arrow to playDownload TWiV 664 (73 MB .mp3, 122 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv (Source: virology blog)
Source: virology blog - September 17, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology common cold coronavirus COVID-19 D614G immunity mutation pandemic reinfection SARS-CoV-2 viral viruses Source Type: blogs

The AstraZeneca/Oxford University Phase 3 COVID-19 Vaccine Trial – Why Was It Paused?
by Helen Stillwell Recently, a Phase 3 trial investigating a COVID-19 vaccine (AZD1222) being developed by AstraZeneca and the University of Oxford was put on hold in the US following a report of an adverse event in a study participant in the U.K. (Feuerstein 2020). One of the predominant vaccine candidates against SARS-CoV-2, AZD1222 is […] (Source: virology blog)
Source: virology blog - September 17, 2020 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Helen Stilwell Information AstraZenca ChAdOx1 COVID-19 Oxford University pandemic SARS-CoV-2 transverse myelitis vaccine viral virus viruses Source Type: blogs

Trial By Error: A Short Talk for UK Docs and Researchers
By David Tuller, DrPH This morning (Wednesday) I gave an informal online talk about the piece of crap known as the PACE trial to a small group of UK doctors, researchers and others. The group had been pulled together by Paul Garner, a physician and professor of infectious diseases at Liverpool School of Tropical Medicine. […] (Source: virology blog)
Source: virology blog - September 17, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized Source Type: blogs

Trial By Error: UK Docs Speak Up on Long-Covid; Mayo Shifts Gears (a Little)
By David Tuller, DrPH Doctors in UK urge caution on long-Covid exercise advice Despite BMJ’s current dereliction of key editorial oversight responsibilities, it has provided a forum for members of the medical community with Covid-19 and post-Covid symptoms to express their strong views. The reference to current dereliction of key editorial responsibilities involves a case […] (Source: virology blog)
Source: virology blog - September 16, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized BMJ long-covid mayo clinic paul garner Source Type: blogs

TWiV 663: The joy of vax
Daniel Griffin provides a clinical report on COVID-19, including vaccines, Alan summarizes a vaccine webinar on the most advanced US trials, a nidovirus from snapping turtles, longevity of memory B cells in recovered patients, and listener email. The British people can face any misfortune with fortitude & buoyancy as long as they are convinced that […] (Source: virology blog)
Source: virology blog - September 15, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antibody clinical trial coronavirus COVID-19 EUA memory B cell nidovirus pandemic plasmablast SARS-CoV-2 snapping turtle vaccine viral viruses Source Type: blogs

Longevity of SARS-CoV-2 memory B cells
Immunity conferred by influenza virus vaccine is short-lived. After immunization with inactivated influenza virus vaccine, serum antibody levels peak within a few months and then decline rapidly. This decline was recently shown to be caused by loss of bone marrow plasma cells, a major source of serum antibodies. Results of a recent study partially address […] (Source: virology blog)
Source: virology blog - September 11, 2020 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information antibody B cell bone marrow plasma cell COVID-19 influenza vaccine memory B cell pandemic plasmablast SARS-CoV-2 viral virus viruses Source Type: blogs

Trial By Error: Some Stuff about Long-Covid, BMJ and ME
By David Tuller, DrPH It is clear that there will be much grappling going forward over the similarities and differences between long-Covid and ME (or CFS, or ME/CFS, or whatever this illness or cluster of illnesses is being called). The two entities overlap in some ways, but no one should conflate them. We are past […] (Source: virology blog)
Source: virology blog - September 11, 2020 Category: Virology Authors: David Tuller Tags: David Tuller ME/CFS BMJ Crawley Lightning Process long-covid Source Type: blogs

TWiV 661: SWAG with Ralph Baric
Ralph Baric returns to TWiV to provide an update on the COVID-19 resurgence in the US, monoclonal antibodies, antiviral drugs, vaccines, immunity and reinfection, reopening schools, and what will happen this fall. Click arrow to playDownload TWiV 661 (70 MB .mp3, 116 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv (Source: virology blog)
Source: virology blog - September 10, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antiviral drug COVID-19 diagnostic test lateral flow assay monoclonal antibody pandemic reinfection SARS-CoV-2 transverse myelitis vaccine virus viruses Source Type: blogs

TWiV 660: In case of emergency finish the trial
Daniel Griffin provides a clinical report on COVID-19, then we discuss decline of virus-specific bone marrow B cells within a year after influenza vaccination, the push to release SARS-CoV-2 vaccines before completion of phase 3 trials, and absence of evidence for infectious virus in aerosols. Click arrow to playDownload TWiV 660 (95 MB .mp3, 159 min)Subscribe […] (Source: virology blog)
Source: virology blog - September 10, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology aerosol transmission bone marrow B cells clinical trial coronavirus COVID-19 diagnostic tests influenza vaccine pandemic SARS-CoV-2 viral viruses Source Type: blogs

TWiV 659: Sloppy coronavirus immunity with Christian Drosten
Christian Drosten returns to TWiV to provide an update on the COVID-19 situation in Germany, and general thoughts on testing, immunity, vaccines, therapeutics, epidemiology, reopening schools, and what will happen this fall. Click arrow to playDownload TWiV 659 (72 MB .mp3, 120 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv (Source: virology blog)
Source: virology blog - September 10, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology coronavirus COVID-19 epidemiology face mask immunity pandemic reinfection SARS-CoV-2 shedding testing transmission vaccine viral viruses Source Type: blogs

The Route Matters
by Gertrud U. Rey Intramuscular injection of a vaccine antigen typically induces a systemic (serum) immune response that involves the action of IgM and IgG antibodies. IgM antibodies appear first and typically bind very strongly to antigens, to the extent that they often cross-react with other, non-specific antigens. IgG antibodies arise later, are a lot more […] (Source: virology blog)
Source: virology blog - September 3, 2020 Category: Virology Authors: Trudy Rey Tags: Gertrud Rey adenovirus-vectored vaccine antibodies IgA IgG IgM infection intramuscular intranasal mucosal immunity SARS-CoV-2 spike protein sterilizing immunity T cells transmission Source Type: blogs

Trial By Error: What Is the Dynamic Neural Retraining System?
By David Tuller, DrPH The Lightning Process, which I have covered extensively, isn’t the only program out there making big assertions about its impact on how the brain functions. These assertions piggyback on the emerging science of neuroplasticity and related concepts and involve the brain’s capacity to generate new neural pathways when it adapts to […] (Source: virology blog)
Source: virology blog - September 3, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized Lightning Process Source Type: blogs

TWiV 658: Everyone needs a H.E.A.R.T.
Daniel Griffin provides a clinical report on COVID-19, then we discuss CDC softening testing guidelines, Moderna vaccine phase I results in older people, Abbott’s $5 rapid antigen test, and reinfection with a distinct SARS-CoV-2 isolate, followed by listener email. Click arrow to playDownload TWiV 658 (85 MB .mp3, 141 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes […] (Source: virology blog)
Source: virology blog - August 31, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antigen test coronavirus COVID-19 diagnostic test lateral flow assay mRNA pandemic PCR SARS-CoV-2 vaccine viral viruses Source Type: blogs

SARS-CoV-2 reinfection: What does it mean?
Not only the popular press but even some of my distinguished science colleagues are claiming that the recent report of reinfection of a COVID-19 patient is the end of the world. Nothing could be farther from the truth. First, the facts. The patient is a healthy Hong Kong male who was diagnosed by PCR with […] (Source: virology blog)
Source: virology blog - August 28, 2020 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Commentary Information antibody common cold coronavirus COVID-19 immunity pandemic reinfection SARS-CoV-2 T cells viral viruses Source Type: blogs

TWiV 657: Shane Crotty on SARS-CoV-2 immunity
Immunologist Shane Crotty joins TWiV to discuss the antibody and T cell responses to infection with SARS-CoV-2, followed by answers to listener questions. (Source: virology blog)
Source: virology blog - August 27, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antibody b cells COVID-19 immune memory immunology pandemic peptide SARS-CoV-2 T cells vaccine viral virus viruses Source Type: blogs

Trial By Error: The Lightning Process Strikes Again
By David Tuller, DrPH The Lightning Process was founded more than two decades ago by Phil Parker, a British Tarot reader and specialist in auras and spiritual guides. The LP, as it is often called, could be described as “a neuro-physiological training programme based on self-coaching, concepts from Positive Psychology, Osteopathy and Neuro Linguistic Programming,” […] (Source: virology blog)
Source: virology blog - August 27, 2020 Category: Virology Authors: David Tuller Tags: David Tuller ME/CFS Crawley Lightning Process norway phil parker Source Type: blogs

TWiV 655: Minority health with Robert Fullilove
Sociomedical scientist Robert Fullilove joins TWiV to discuss disparities in minority health; FDA announces an EUA on Yale’s SalivaDirect, protection of the upper and respiratory tract of mice after intranasal inoculation with an adenovirus-vectored SARS-CoV-2 spike gene, and listener questions. (Source: virology blog)
Source: virology blog - August 21, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology adenovirus coronavirus COVID-19 HIV/AIDS minority health mucosal immunity pandemic SalivaDirect SARS-CoV-2 vaccine viral viruses Source Type: blogs

Pandemics and anthropogenic environmental change
All human viruses have their origin in a virus that crossed from a different animal species. The encounters that lead to these spillovers are driven by explosive human population growth and incredible change occurring in all ecosystems brought about by human occupation of almost every corner of the planet. The extent to which land-use change […] (Source: virology blog)
Source: virology blog - August 21, 2020 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information anthropogenic bat COVID-19 ecology pandemic SARS-CoV-2 spillover viral virus viruses zoonotic disease Source Type: blogs

TWiV 654: TWiVering with excitement
Daniel Griffin provides a clinical report on COVID-19 and the convalescent plasma trial, then we answer listener questions about the Russian vaccine, choir practice, face masks (wear them!), Mina testing, transmission, and much more. Click arrow to playDownload TWiV 654 (93 MB .mp3, 156 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv (Source: virology blog)
Source: virology blog - August 18, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology convalescent plasma coronavirus COVID-19 droplet transmission face mask Mina antigen test SARS-CoV-2 viral viruses Source Type: blogs

Trial By Error: FITNET-NHS Falls Short in Recruitment Drive
By David Tuller, DrPH Professor Esther Crawley, Bristol University’s methodologically and ethically challenged pediatrician and star researcher, has weighed in with an interim analysis of FITNET-NHS, her trial of online cognitive behavior therapy for adolescents with what she calls CFS/ME. Poor Professor Crawley! Despite her ambitious goal of enrolling a whopping 734 participants, early recruitment […] (Source: virology blog)
Source: virology blog - August 18, 2020 Category: Virology Authors: David Tuller Tags: David Tuller ME/CFS Esther Crawley FITNET Netherlands online CBT Source Type: blogs

TWiV 653: Back to school with COVID-19
Alfonso, Ken, Mary and Janet join TWiV to explain their modeling of school reopening strategies during the SARS-CoV-2 pandemic. Click arrow to playDownload TWiV 653 (34 MB .mp3, 56 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv (Source: virology blog)
Source: virology blog - August 14, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology COVID-19 mathematical model pandemic SARS-CoV-2 school reopening transmission viral virus viruses Source Type: blogs

The future of SARS-CoV-2
What does the future hold for SARS-CoV-2? Will it remain in its current configuration, with 20% of infections causing serious damage? Will everyone on Earth need to be vaccinated regularly to prevent infection? Allow me to indulge in some speculation and suggest that SARS-CoV-2 will eventually become the fifth common cold coronavirus (CoV). There are […] (Source: virology blog)
Source: virology blog - August 14, 2020 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Commentary Information COVID-19 evolution pandemic SARS-CoV-2 selection transmission vaccine viral virulence virus viruses Source Type: blogs

TWiV 652: The rules of contagion with Adam Kucharski
Epidemiologist Adam Kucharski joins TWiV to discuss SARS-CoV-2, including R0, incubation period, herd immunity, asymptomatic infection, superspreaders, children as drivers of pandemics, and how this one will end. Click arrow to playDownload TWiV 652 (69 MB .mp3, 114 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv (Source: virology blog)
Source: virology blog - August 13, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology coronavirus COVID-19 epidemiology incubation period R0 reproductive index SARS-CoV-2 superspreader transmission viral viruses Source Type: blogs

Trial By Error: More CBT Research from Sir Simon and Professor Chalder
By David Tuller, DrPH (*Thanks to the the very informed discussion–and discussants–on the Science For ME forum for alerting me to this study and its many problems!) In 2011, Professor Trudie Chalder declared at a press conference for the high-profile PACE trial that twice as many chronic fatigue syndrome patients who received cognitive behavior therapy […] (Source: virology blog)
Source: virology blog - August 12, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized CBT chalder PACE Wessely Source Type: blogs

TWiN 9: COVID-19 neurology with Genna Waldman
Columbia University Chief Neurology Resident Genna Waldman joins TWiN to explains how her department prepared for COVID-19, and the neurological symptoms associated with the disease. Click arrow to playDownload TWiN 009  (40 MB .mp3, 67 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Show notes at microbe.tv/twin (Source: virology blog)
Source: virology blog - August 12, 2020 Category: Virology Authors: Vincent Racaniello Tags: Uncategorized cognitive defect coma COVID-19 hypoxia neurobiology neuroinvasion neurological symptoms neurology neuropathology neuroscience pandemic SARS-CoV-2 stroke thrombosis Source Type: blogs

Trial By Error: Recent Posts on Dutch Stuff from Simon McGrath and Lou Corsius
By David Tuller, DrPH Last week I wrote about the questionable decision by Dutch health funders to support a new research project from Professor Hans Knoop, a high-profile member of the CBT/GET ideological brigades. Although full details were not available, the project appeared to presume that post-Covid syndrome patients could benefit from cognitive restructuring designed […] (Source: virology blog)
Source: virology blog - August 11, 2020 Category: Virology Authors: David Tuller Tags: David Tuller ME/CFS corsius Knoop mcgrath Netherlands Source Type: blogs

TWiV 651: FDA rules with Denise Esposito
Daniel Griffin provides a clinical report on COVID-19, then former FDA Chief of Staff to the Commissioner Denise Esposito joins us to explain the challenges in approving vaccines, antiviral drugs, and diagnostic tests during a pandemic, followed by answers to listener questions. Click arrow to playDownload TWiV 651 (98 MB .mp3, 164 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become […] (Source: virology blog)
Source: virology blog - August 9, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antiviral drug clinical trials coronavirus COVID-19 diagnostic test emergency use authorization EUA FDA pandemic SARS-CoV-2 test validation vaccine viruses Source Type: blogs

Trial By Error: And Now – No Surprise – CBT for Post-Covid Fatigue
By David Tuller, DrPH Old habits die hard. So do bad ideas. Especially when these old habits and bad ideas have formed the basis for prominent academic and medical careers in the UK and the Netherlands. In the UK, Professor Trudie Chalder of King’s College London has advised patients with prolonged fatigue after an acute […] (Source: virology blog)
Source: virology blog - August 8, 2020 Category: Virology Authors: David Tuller Tags: David Tuller ME/CFS Source Type: blogs

TWiV 650: Virology is infinite
In this mid-week episode of Earth’s Virology Podcast, we analyze SARS-CoV-2 transmission among youths at a summer camp, adaptation to mice by passage, the importance of T cells for recovery from COVID-19, and listener questions. Click arrow to playDownload TWiV 650 (73 MB .mp3, 122 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv (Source: virology blog)
Source: virology blog - August 7, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology childhood transmission coronavirus COVID-19 mouse model opening schools pandemic pneumonia SARS-CoV-2 T cells viral virusesl Source Type: blogs

How to End this Pandemic
by Gertrud U. Rey As of today, SARS-CoV-2 has infected 18.7 million people and caused 700,000 deaths worldwide. The most realistic way to quickly curb the spread of the virus would require daily identification and isolation of individuals who are contagious, a process that is hampered by cumbersome sampling and testing methods with slow turnaround […] (Source: virology blog)
Source: virology blog - August 7, 2020 Category: Virology Authors: Vincent Racaniello Tags: Gertrud Rey coronavirus COVID-19 Michael Mina pandemic rapid antigen test saliva SARS-CoV-2 viral virology viruses Source Type: blogs

Trial By Error: From UK ’ s National Health Service, “ Your COVID Recovery ”
By David Tuller, DrPH In the UK, the National Health Service has launched a website called “Your COVID Recovery,” part of its strategy for coping with the after-effects of the coronavirus pandemic. This effort is geared toward “supporting your recovery after COVID-19.” In other words, it appears to be targeting the “long-haulers,” as those experiencing […] (Source: virology blog)
Source: virology blog - August 5, 2020 Category: Virology Authors: David Tuller Tags: David Tuller ME/CFS National Health Service post-covid syndrome Source Type: blogs

TWiV 649: Ohio State viral
Vincent visits Ohio State University (March 2020) and speaks with Shan-Lu, David, Amanda, Mark, Matt, Chris, and Qiuhong about their careers and their work on retroviruses, hepatitis C virus, coronaviruses, paramyxoviruses, and environmental viruses. Click arrow to playDownload TWiV 650 (63 MB .mp3, 105 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv (Source: virology blog)
Source: virology blog - August 4, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology coronavirus COVID-19 hepatitis C virus HTLV pandemic plant viruses retrovirus SARS-CoV-2 viral viroids Source Type: blogs

TWiV 648: Life is for learning
Daniel Griffin provides a clinical report on COVID-19, followed by a review of the findings that children shed as much SARS-CoV-2 viral RNA from the respiratory tract as older patients, the lineage giving rise to SARS-CoV-2 has been circulating in bats in China for decades, and answers to listener questions. Click arrow to playDownload TWiV 648 […] (Source: virology blog)
Source: virology blog - August 4, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology bats coronavirus COVID-19 evolution face mask nasopharyngeal shedding pandemic SARS-CoV-2 vaccine viral viruses Wuhan Yunnan Source Type: blogs

Trial By Error: Some Stuff to Read and Watch From Rivka, Natalie & Anil
By David Tuller, DrPH Massachussetts writer Rivka Solomon has had severe ME for many years but still manages to get out there (metaphorically) and organize lots of stuff. A couple of years ago, she arranged a talk for me to give about the PACE trial debacle at a Boston-area hospital. She’s also pulled together a […] (Source: virology blog)
Source: virology blog - August 3, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized anil van der zee Ed markey natalie boulton Rivka solomon Source Type: blogs

Children transmit SARS-CoV-2
Among the mountains of false information being peddled during the current pandemic, one of the most offensive is being used to drive opening of schools in the fall: that children do not transmit SARS-CoV-2. The results of multiple studies have shown that this assertion is incorrect. I’ll review two of them here. One study examined […] (Source: virology blog)
Source: virology blog - July 31, 2020 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Commentary COVID-19 cycle threshold diagnostic testing pandemic PCR SARS-CoV-2 school opening transmission in children viral virus viruses Source Type: blogs

Trial By Error: Disinformation About Treatments for Post-Covid Syndrome
By David Tuller, DrPH Professor Trudie Chalder is a lead investigator of a series of studies of rehabilitative interventions for so-called “medically unexplained symptoms” that have failed to meet expectations but have nevertheless been promoted as demonstrating treatment success. The piece of crap known as the PACE trial is a prime example. Most famously, Professor […] (Source: virology blog)
Source: virology blog - July 28, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized chalder PACE post-covid syndrome Source Type: blogs

TWiV 645: Lions and tigers and zookeepers (oh my)
Daniel Griffin provides a clinical report on COVID-19, followed by a review of the State Department document on the Wuhan BSL-4 laboratory, the report on infection of tigers and lions in the Bronx Zoo, and, answers to listener questions. Click arrow to playDownload TWiV 645 (98 MB .mp3, 163 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes […] (Source: virology blog)
Source: virology blog - July 27, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology Bronx Zoo BSL-4 laboratory coronavirus COVID-19 diagnostic test lion pandemic SARS-CoV-2 tiger viral viruses Wuhan Source Type: blogs

Trial By Error: Columbia Experts Urge BMJ to Retract Problem-Plagued Study
By David Tuller, DrPH On Thursday, Professors Vincent Racaniello and Mady Hornig, both from Columbia University, wrote to BMJ’s research integrity coordinator. I have been corresponding with BMJ, and specifically the research integrity coordinator, about the Norwegian study of cognitive behavior therapy combined with music therapy as a treatment for chronic fatigue in adolescents after […] (Source: virology blog)
Source: virology blog - July 25, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized BMJ CBT mononucleosis music therapy norway Source Type: blogs

Trial By Error: Columbia Experts Urge BMJ to Retract Not-Fully-Reviewed Study
By David Tuller, DrPH On Thursday, Professors Vincent Racaniello and Mady Hornig, both from Columbia University, wrote to BMJ’s research integrity coordinator. I have been corresponding with BMJ, and specifically the research integrity coordinator, about the Norwegian study of cognitive behavior therapy combined with music therapy as a treatment for chronic fatigue in adolescents after […] (Source: virology blog)
Source: virology blog - July 25, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized BMJ CBT mononucleosis music therapy norway Source Type: blogs

Preliminary phase I/II results of ChAdOx1 SARS-CoV-2 vaccine
by Gertrud U. Rey On July 20, 2020, Oxford University’s Jenner Institute and the pharmaceutical company AstraZeneca reported preliminary results from phase I/II clinical trials assessing the safety and efficacy of a vaccine candidate against SARS-CoV-2.  The vaccine candidate, named AZD1222 (referred to in the publication as ChAdOx1 nCoV-19), consists of an adenovirus vector with an […] (Source: virology blog)
Source: virology blog - July 23, 2020 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information adenovirus AstraZeneca ChAdOx1 COVID-19 Oxford University pandemic SARS-CoV-2 vaccine viral viruses Source Type: blogs

TWiV 644: Don ’ t let perfect be the enemy of good
In this mid-week edition, identifying flawed research before it becomes dangerous, Michigan governor tells America to mask-up, Pfizer mRNA vaccine gets $1.95 billion from Warp Speed, preliminary phase I/II results of the ChAdOx1 SARS-CoV-2 vaccine, answers to listener questions. Click arrow to playDownload TWiV 644 (69 MB .mp3, 115 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes […] (Source: virology blog)
Source: virology blog - July 23, 2020 Category: Virology Authors: Vincent Racaniello Tags: Uncategorized ChAdOx1 COVID-19 face mask pandemic Pfizer mRNA vaccine SARS-CoV-2 viral virology virus viruses Warp Speed Source Type: blogs

TWiV 643: Bernie Moss, the real Poxdoc
From the NIH campus (recorded February 2019) Vincent and Rich meet with Bernie Moss to hear about his training and his remarkable 50-year-plus career working on poxviruses. Click arrow to playDownload TWiV 643 (67 MB .mp3, 112 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv (Source: virology blog)
Source: virology blog - July 22, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology mRNA capping poxvirus smallpox virus vaccinia virus viral viral vector viruses Source Type: blogs

TWiV 642: Bringin ’ in 50 keys of spike mRNA
Daniel Griffin provides a clinical update on COVID-19, then we discuss phase I preliminary results of the SARS-CoV-2 mRNA vaccine, factors associated with death in 17 million patients, and answer listener questions. (Source: virology blog)
Source: virology blog - July 22, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology comorbidities COVID-19 Moderna mRNA vaccine OpenSafely pandemic SARS-CoV-2 viral virus viruses Source Type: blogs

Trial By Error: Another Letter About BMJ ’ s Music Therapy Study
By David Tuller, DrPH I am still waiting for answers from BMJ about the Norwegian study of cognitive behavior therapy plus music therapy for treatment of chronic fatigue in adolescents after mononucleosis. The study was published in BMJ Paediatrics Open. I have written about it here. This morning I sent the following letter to the […] (Source: virology blog)
Source: virology blog - July 21, 2020 Category: Virology Authors: David Tuller Tags: David Tuller ME/CFS BMJ CBT music therapy norway Source Type: blogs

Trial By Error: No Evidence for CBT and Other “ Conversion Disorder ” Therapies
By David Tuller, DrPH I have recently written critically about the CODES trial of cognitive behavior therapy as a treatment for the phenomena that have long been called “psychogenic non-epileptic seizures” but that some neurologists and psychologists are trying to rebrand as “dissociative seizures.” (Many people understandably find it offensive to be told they have […] (Source: virology blog)
Source: virology blog - July 20, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized Source Type: blogs

TWiV 641: COVID-19 with Dr. Anthony Fauci
Dr. Anthony Fauci joins TWiV to discuss SARS-CoV-2 transmission, testing, immunity, pathogenesis, vaccines, and preparedness. Click arrow to playDownload TWiV 641 (22 MB .mp3, 36 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Dr. Fauci was previously on TWiV 219 Intro music is by Ronald Jenkees (Source: virology blog)
Source: virology blog - July 18, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology COVID-19 immunity pandemic pathogenesis preparedness SARS-CoV-2 transmission vaccines viral virus viruses Source Type: blogs