Trial By Error: Does Functional Neurology Disorder Account for a Third of Outpatient Neurology Consults?
By David Tuller, DrPH Functional neurological disorder, or FND, is the new-ish name for the hoary Freudian construct known as conversion disorder. For decades, psychiatrists informed patients that they were “converting” their emotional distress and anxieties into physical symptoms like tremors, seizures, sensory and cognitive deficits, a halting gait, or other physical dysfunctions. The impossibility […] (Source: virology blog)
Source: virology blog - June 16, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized FND functional neurological disorder Source Type: blogs
Trial By Error: A Reprise of an Earlier Blog Post About Godwin ’ s Law on Nazi Analogies and Simon Wessely
By David Tuller, DrPH In a new book, Fiona Fox, the head of the London-based Science Media Centre, has compared critics of the GET/CBT ideological brigades and the PACE trial to Nazis, as I noted recently on Virology Blog. In response to her unfortunate reference to the Holocaust in this context, some on social media […] (Source: virology blog)
Source: virology blog - June 7, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized Fiona Fox godwin's law mike godwin nazis science media centre Source Type: blogs
TWiV 906: Long COVID, giant viruses, and smallish pox
TWiV reviews human monkeypox infections, evidence for human Mimivrus infections, and incidence of long COVID in post-vaccine SARS-CoV-2 infections. (Source: virology blog)
Source: virology blog - June 5, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology Source Type: blogs
Trial By Error: Science Media Centre Chief Fiona Fox Compares ME/CFS Patient Advocates to Nazis
By David Tuller, DrPH I have called the PACE trial of graded exercise therapy (GET) and cognitive behavior therapy (CBT) for ME/CFS “a piece of crap.” As I have indicated over the years, I think the trial is an example of serious research misconduct. (Whether it meets legal definitions of “fraud” is beyond my professional […] (Source: virology blog)
Source: virology blog - June 4, 2022 Category: Virology Authors: David Tuller Tags: David Tuller ME/CFS Fiona Fox science media centre Source Type: blogs
Trial By Error: Science Media Centre Chief Compares Patient Advocates to Nazis
By David Tuller, DrPH I have called the PACE trial of graded exercise therapy (GET) and cognitive behavior therapy (CBT) for ME/CFS “a piece of crap.” As I have indicated over the years, I think the trial is an example of serious research misconduct. (Whether it meets legal definitions of “fraud” is beyond my professional […] (Source: virology blog)
Source: virology blog - June 4, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized Fiona Fox science media centre Source Type: blogs
TWiV 905: COVID-19 clinical update #117 with Dr. Daniel Griffin
In COVID-19 clinical update #117, Dr. Griffin discusses duration of virus shedding, association between pre-exposure to steroids and infection outcome, post-infection subtypes, rehabilitation for post-acute infection, Tixagevimab/Cilgavimab for infection prevention, antibody prophylaxis and vaccination in kidney transplant recipients, remdesivir and bebtelovimab fact sheets for providers, the updated guidelines on treatment with Famotidine, Paxlovid rebound symptom characterizations, antigen test positivity duration, viral dynamics of variants and isolation, association of inflammation in CS fluid, and transmission dynami...
Source: virology blog - June 4, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antiviral coronavirus COVID-19 delta inflammation Long Covid monoclonal antibody Omicron pandemic SARS-CoV-2 vaccine vaccine booster variant of concern viruses Source Type: blogs
Herd Immunity and this Pandemic
by Gertrud U. Rey Herd immunity occurs when a large enough percentage of the population has acquired either natural or vaccine-induced immunity against an infectious disease, thereby indirectly protecting a minority of non-immune individuals who are dispersed throughout the population. During this pandemic, many prominent scientists have stated that it is impossible to achieve herd […] (Source: virology blog)
Source: virology blog - June 2, 2022 Category: Virology Authors: Gertrud U. Rey Tags: Basic virology Gertrud Rey antibody disease herd immunity infection neutralizing antibody pandemic sterilizing immunity transmission vaccine Source Type: blogs
Trial By Error: Deja Vu All Over Again with Proposed Lightning Process Study in Norway
By David Tuller, DrPH It’s déjà vu all over again in Norway with the Lightning Process (LP). Earlier this month, a national research ethics authority, NEM, postponed a decision on a proposed LP trial until at least June. The trial has already been approved by a regional committee. The NEM had been expected to decide […] (Source: virology blog)
Source: virology blog - May 31, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized Lightning Process Live Landmark norway phil parker Source Type: blogs
TWiV 904: 50 years of reverse transcriptase
Vincent travels to Cold Spring Harbor Laboratory to speak with David Baltimore, John Coffin, and Harold Varmus about the discovery in 1970 of retroviral reverse transcriptase and its impact on life sciences research. (Source: virology blog)
Source: virology blog - May 29, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology reverse transcriptase rna tumor virus viral viruses Source Type: blogs
Richard R Ernst Lecture 2022 – Vincent Racaniello
It was my great honor to be selected as the Richard R Ernst Lecturer for 2022. The aim of the Richard R. Ernst Lecture is to strengthen the relationship and understanding between the sciences, society, and politics and to raise awareness for the questions and challenges our global society is facing today and will face in the future. (Source: virology blog)
Source: virology blog - May 28, 2022 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information COVID-19 pandemic public discourse Richard R Ernst science science communication viral virus viruses Source Type: blogs
TWiV Special: Monkeypox clinical update with Dr. Daniel Griffin
In this special episode, Dr. Griffin answers questions about the recent cases of monkeypox including their origin, clinical presentation, diagnosis, treatment, and overall risk. (Source: virology blog)
Source: virology blog - May 27, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology monkeypox smallpox vaccine viral virus viruses zoonosis Source Type: blogs
Trial By Error: An Innumerate Response from Chalder to Hughes-Tuller Comments on Bogus Data Analysis
By David Tuller, DrPH Last year, King College London’s professor of cognitive behaviour therapy, Trudie Chalder, published another one of her extremely incompetent papers. This one is so statistically challenged as to be truly mind-boggling, even by Professor Chalder’s extremely low standards. A team of purportedly expert researchers has mangled descriptions of their own data […] (Source: virology blog)
Source: virology blog - May 26, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized Source Type: blogs
Trial By Error: Speaker at CDC Event Promotes CBT and “ Very Gradual ” GET
By David Tuller, DrPH The US Centers for Disease Control and Prevention has a long history of missteps when it comes to the illness or cluster of illnesses currently called ME/CFS—as anyone who has read Osler’s Web knows. In the more recent past—2017–the agency dropped its unfortunate endorsement of the discredited GET/CBT treatment approach but […] (Source: virology blog)
Source: virology blog - May 23, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized CDC Gluckman MSD Manual Up-to-Date Source Type: blogs
TWiV 902: Autoantibodies drive severe COVID-19
TWiV reviews recent cases of monkeypox, presence of SARS-CoV-2 RNA but not infectious virus in feces, and the association of autoantibodies to interferons with severe COVID-19. (Source: virology blog)
Source: virology blog - May 22, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology autoantibodies coronavirus COVID-19 feces interferon monkeypox pandemic SARS-CoV-2 smallpox viral viruses Source Type: blogs
TWiV 901: COVID-19 clinical update #115 with Dr. Daniel Griffin
In COVID-19 clinical update #115, Dr. Griffin reviews cross-variant immunity without vaccination, EUA for boosters in 5-11 year olds, B.1.1.529 attack rate, scent dogs, Omicron and pets, Paxlovid, Veklury, Fluvoxamine, antigen positivity after isolation, inflammasome activation and severe disease, and GI persistence and fecal shedding. (Source: virology blog)
Source: virology blog - May 21, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antiviral coronavirus COVID-19 delta inflammation Long Covid monoclonal antibody Omicron pandemic SARS-CoV-2 vaccine vaccine booster variant of concern viruses Source Type: blogs
