Trial By Error: Guardian Columnist George Monbiot Calls Out the GET/CBT Charlatans and the Fraudulent PACE Trial
By David Tuller, DrPH In a blistering take-down published on Tuesday, Guardian columnist George Monbiot indicted Professor Sir Simon Wessely, Professor Michael Sharpe and the rest of the GET/CBT ideological brigades for their decades-long promotion of discredited theories about and bogus research into the cluster of illnesses now being called ME/CFS. Those theories and research … Trial By Error: Guardian Columnist George Monbiot Calls Out the GET/CBT Charlatans and the Fraudulent PACE Trial Read More » (Source: virology blog)
Source: virology blog - March 14, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized Guardian monbiot PACE Sharpe Wessely Source Type: blogs
Trial By Error: Letter to BMJ Seeking Correction in Study of Long Covid Physical-and-Mental Rehabilitation Program
By David Tuller, DrPH Last month, The BMJ published a study of a rehab intervention for Long Covid in which the authors made claims that were not borne out by the data. The study was called “Clinical effectiveness of an online supervised group physical and mental health rehabilitation programme for adults with post-covid-19 condition (REGAIN … Trial By Error: Letter to BMJ Seeking Correction in Study of Long Covid Physical-and-Mental Rehabilitation Program Read More » (Source: virology blog)
Source: virology blog - March 11, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized BMJ Long Covid mcgregor warwick Source Type: blogs
Trial By Error: Will MAGENTA ’ s Null Results Finally End Professor Crawley ’ s Long ‘ Reign of Error ’ ?
By David Tuller, DrPH For years, Professor Esther Crawley, the University of Bristol’s methodologically and ethically challenged ME/CFS investigator, has hoovered up millions of pounds from public and private funders to support her misbegotten research. She achieved this success as a grant magnet despite abundant and easily available evidence that she was violating core principles … Trial By Error: Will MAGENTA’s Null Results Finally End Professor Crawley’s Long ‘Reign of Error’? Read More » (Source: virology blog)
Source: virology blog - March 10, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized Bristol Crawley GET MAGENTA Source Type: blogs
Dogma Does Not Belong in Science
by Gertrud U. Rey According to established scientific dogma, infection of cells with HIV-1 leads to delivery of the viral capsid into the cell cytoplasm, followed by “uncoating” of the capsid to release the single-stranded RNA genome. A viral-encoded enzyme called reverse transcriptase then catalyzes the conversion of the viral RNA into a single strand … Dogma Does Not Belong in Science Read More » (Source: virology blog)
Source: virology blog - March 7, 2024 Category: Virology Authors: Gertrud U. Rey Tags: Uncategorized Source Type: blogs
Trial By Error: An Interview with Neuroscientist Michael VanElzakker about the Just-Published and Long-Awaited NIH Study
By David Tuller, DrPH So, okay…The big enchilada from the US National Institutes of Health’s seven-year, $8-million, under-recruited and over-hyped study—”Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome”–was published last week in Nature Communications. It would be fair to describe the ensuing public debate over this massive text-and-data dump as spirited. (NIH press release here; … Trial By Error: An Interview with Neuroscientist Michael VanElzakker about the Just-Published and Long-Awaited NIH Study Read More » (Source: virology blog)
Source: virology blog - February 28, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized effort preference NIH vanElzakker Source Type: blogs
Trial By Error: New Long Covid Exercise-and-Therapy Study Claims Success Despite Clinically Insignificant Findings
By David Tuller, DrPH A new study of an online group physical and psychological rehabilitation program for Long Covid confirms once again that people given an intervention purporting to help them are more likely to tell investigators that they feel better than those given nothing of the kind. People, this is not a surprising result! … Trial By Error: New Long Covid Exercise-and-Therapy Study Claims Success Despite Clinically Insignificant Findings Read More » (Source: virology blog)
Source: virology blog - February 20, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized Source Type: blogs
Trial By Error: Sarah Boothby Discusses Second Pre-Inquest Hearing into Death of Daughter Maeve from ME Complications
By David Tuller, DrPH Maeve Boothby O’Neill died of complications from ME in Exeter, England, in October, 2021, after three admissions to the local hospital. (I wrote about Maeve’s life and death last year for Codastory.com.) Since then, the family has been waiting for an inquest to be held into the circumstances of her death … Trial By Error: Sarah Boothby Discusses Second Pre-Inquest Hearing into Death of Daughter Maeve from ME Complications Read More » (Source: virology blog)
Source: virology blog - February 15, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized death inquest Maeve Boothby O'Neill Source Type: blogs
Trial By Error: Leading FND Site Confirms Criticisms on Prevalence Outlined in Our Letter to Neurology Journal
By David Tuller, DrPH In two recent posts, here and here, I wrote about our letter on inflated prevalence claims for functional neurological disorder (FND) and about the response from the authors of the study we criticized. The 2021 article in NeuroImage: Clinical, “Neuroimaging in functional neurological disorder: state of the field and research agenda,” asserted … Trial By Error: Leading FND Site Confirms Criticisms on Prevalence Outlined in Our Letter to Neurology Journal Read More » (Source: virology blog)
Source: virology blog - February 13, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized FND functional neurological disorder Jon Stone neuroImage: clinical Source Type: blogs
Trial By Error: Unconvincing Response to Letter on FND Prevalence Inflation
By David Tuller, DrPH As I wrote in a post the other day, the journal NeuroImage: Clinical has just published a letter from a group I organized about the misrepresentation of findings regarding the prevalence of functional neurological disorder (FND). They have also published a response from the authors of the article we criticized. The … Trial By Error: Unconvincing Response to Letter on FND Prevalence Inflation Read More » (Source: virology blog)
Source: virology blog - February 12, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized Source Type: blogs
Trial By Error: Finally, Our Letter on Inflated Claims of FND Prevalence Is Published
By David Tuller, DrPH For more than a year, I have been criticizing experts in the field of functional neurological disorder for misrepresenting the findings of a seminal study, in effect tripling the reported prevalence rate of the condition. These untrue claims about the Scottish Neurological Symptoms Study (SNSS)—specifically, that the prevalence of FND among … Trial By Error: Finally, Our Letter on Inflated Claims of FND Prevalence Is Published Read More » (Source: virology blog)
Source: virology blog - February 9, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized conversion disorder FND FND prevalence Source Type: blogs
Let ’ s Talk About Measles
by Gertrud U. Rey Recent news headlines have been featuring multiple outbreaks of measles across the globe, and an announcement from the Centers for Disease Control and Prevention dated January 25, 2024, also reported 23 confirmed cases in the US over the past month. These outbreaks happen every few years and are usually triggered by … Let’s Talk About Measles Read More » (Source: virology blog)
Source: virology blog - February 1, 2024 Category: Virology Authors: Gertrud U. Rey Tags: Basic virology Gertrud Rey basic reproductive number contagious herd immunity herd immunity threshold immune measles measles virus mmr vaccine outbreak R0 transmissibility transmissible vaccination Source Type: blogs
Trial By Error: Yet Another Meta-Analysis Purporting to Prove that CBT Is Effective for “ Chronic Fatigue Syndrome ”
By David Tuller, DrPH I just wrote about how PACE was favorably cited in an article in Nature Reviews Cardiology. Last month, that piece of crap was also included as part of yet another meta-analysis that mushed together the findings from a load of bad papers and concluded that, collectively, they prove something or other. … Trial By Error: Yet Another Meta-Analysis Purporting to Prove that CBT Is Effective for “Chronic Fatigue Syndrome” Read More » (Source: virology blog)
Source: virology blog - January 31, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized CBT meta-analysis Source Type: blogs
Trial By Error: Yet Another ME-Related Death
By David Tuller, DrPH It has been a season of loss. Two weeks ago, I posted an obituary for the much-loved ME patient advocate Beth Mazur, who co-founded #MEAction and suffered with the disease for years. Last October, I posted tributes to Celine Corsius from her parents and brother; Celine died by euthanasia under Dutch … Trial By Error: Yet Another ME-Related Death Read More » (Source: virology blog)
Source: virology blog - January 30, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized Beth mazur Celine Corsius death euthanasia Lauren Source Type: blogs
Trial By Error: Debate Over Recent Citation of Arguably Fraudulent PACE Trial
By David Tuller, DrPH Having a discussion about the PACE trial with someone who still maintains it was a well-conducted study is like debating the 2020 election with a Trumper who insists that Biden lost. These two distinct groups exhibit the same remarkable inability or willful refusal to understand and accept reality, whether it involves … Trial By Error: Debate Over Recent Citation of Arguably Fraudulent PACE Trial Read More » (Source: virology blog)
Source: virology blog - January 28, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized cardiology Eric Topol Long Covid nature PACE PEM Source Type: blogs
Trial By Error: Interview with Dr Rob W üst about New Study of Muscle Abnormalities in Long Covid
By David Tuller, DrPH In early January, Nature Communications published a Dutch study called “Muscle abnormalities worsen after post-exertional malaise in long COVID.” The study caused a buzz among patients, clinicians, and other researchers and generated extensive news coverage. Called. (I wrote a blog post about it here.) The investigators identified significant biological differences after … Trial By Error: Interview with Dr Rob Wüst about New Study of Muscle Abnormalities in Long Covid Read More » (Source: virology blog)
Source: virology blog - January 26, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized Long Covid muscles post-exertional malaise Wust Source Type: blogs
