Fighting Viruses with Viruses
by Gertrud U. Rey Errors during viral replication can give rise to shortened and/or rearranged genomic sequences known as “defective viral genomes” (DVGs). Because DVGs often lack critical elements needed for replication and formation of new viral particles, virions containing DVGs can only complete a replication cycle if they co-infect a cell together with respective […] (Source: virology blog)
Source: virology blog - May 5, 2022 Category: Virology Authors: Gertrud U. Rey Tags: Basic virology Gertrud Rey antiviral Chikungunya virus defective viral genomes dengue virus DVGs mosquitoes zika virus Source Type: blogs

TWiV 896: Memory B cells, the way we were
TWiV explains a study of how climate change is predicted to increase cross-species viral transmission risk, and increased memory B cell potency and breadth after a SARS-CoV-2 mRNA vaccine boost. Hosts: Vincent Racaniello, Dickson Despommier, and Amy Rosenfeld Click arrow to playDownload TWiV 896 (65 MB .mp3, 108 min)Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at […] (Source: virology blog)
Source: virology blog - May 1, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antibody climate change COVID-19 memory B cell pandemic SARS-CoV-2 variant of concern viral virus viruses zoonosis Source Type: blogs

TWiV 895: COVID-19 clinical update #112 with Dr. Daniel Griffin
In COVID-19 clinical update #112, Dr. Griffin reviews seroprevalence of infection-induced antibodies, Moderna filing for vaccine authorization in young children, public health impact of vaccines in US, FDA approval of first treatment for young children, phase 2 data for Sabizabulin, and post infection inflammation. (Source: virology blog)
Source: virology blog - April 30, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antiviral coronavirus COVID-19 delta inflammation Long Covid monoclonal antibody Omicron pandemic SARS-CoV-2 vaccine vaccine booster variant of concern viruses Source Type: blogs

TWiV 894: Dinner with the TMPRSS family
TWiV explains what is known about cases of acute, severe hepatitis of unknown origin in children, and discovery of an inhibitor of TMPRSS2 protease that blocks SARS-CoV-2 infection. (Source: virology blog)
Source: virology blog - April 29, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology adenovirus antiviral drug coronavirus COVID-19 hepatitis pandemic peptidomimetic SARS-CoV-2 Tmprss2 viruses Source Type: blogs

Trial By Error: Now a Scottish Long Covid Study Fails to Mention the Risk of Post-Exertional Malaise
By David Tuller, DrPH *April is crowdfunding month at UC Berkeley. If you like my work, consider making a tax-deductible donation to Berkeley’s School of Public Health to support the Trial By Error project: https://crowdfund.berkeley.edu/project/31347 And here’s another major trial designed by investigators who think that an exercise program might be the optimal strategy for treating […] (Source: virology blog)
Source: virology blog - April 23, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized exercise glasgow Long Covid Source Type: blogs