Trial By Error: Interview with Dr Rob W üst about New Study of Muscle Abnormalities in Long Covid
By David Tuller, DrPH In early January, Nature Communications published a Dutch study called “Muscle abnormalities worsen after post-exertional malaise in long COVID.” The study caused a buzz among patients, clinicians, and other researchers and generated extensive news coverage. Called. (I wrote a blog post about it here.) The investigators identified significant biological differences after … Trial By Error: Interview with Dr Rob Wüst about New Study of Muscle Abnormalities in Long Covid Read More » (Source: virology blog)
Source: virology blog - January 26, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized Long Covid muscles post-exertional malaise Wust Source Type: blogs
Trial By Error: Reporter Betsy Ladyzhets on Last Week ’ s US Senate Hearing
By David Tuller, DrPH Last Thursday (January 18th), the Senate Committee on Health, Education, Labor, & Pensions held a hearing called “Addressing Long COVID: Advancing Research and Improving Patient Care.” The bipartisan panel included senators who are also physicians and as well as Democrat Tim Kaine of Virginia, who has been open about his own … Trial By Error: Reporter Betsy Ladyzhets on Last Week’s US Senate Hearing Read More » (Source: virology blog)
Source: virology blog - January 24, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized Ladyzhets Long Covid Senate sick times tim kaine Source Type: blogs
Trial By Error: Obituary for Beth Mazur
By Brian Vastag Beth Anne Mazur, a fierce but unassuming advocate for people with a devastating — and devastatingly neglected — chronic illness, died on Dec. 21, 2023, in the mountains above Santa Fe, N.M. She was 47 years old. Beth leaves behind a wide circle of dear friends; many partners in patient advocacy; a … Trial By Error: Obituary for Beth Mazur Read More » (Source: virology blog)
Source: virology blog - January 12, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized Beth mazur Brian Vastag MEAction obituary Source Type: blogs
Trial By Error: Study Finds “ Elevated Brain Injury Markers and Reduced Grey Matter Volume ” a Year After Hospitalization for COVID-19
By David Tuller, DrPH A British study of neurological sequelae in patients many months after hospitalization for COVID-19 has found that “post acute cognitive deficits…were associated with elevated brain injury markers in serum and reduced grey matter volume,” according to a pre-print posted earlier this week. (A pre-print is a paper that has not yet … Trial By Error: Study Finds “Elevated Brain Injury Markers and Reduced Grey Matter Volume” a Year After Hospitalization for COVID-19 Read More » (Source: virology blog)
Source: virology blog - January 12, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized covid-cns FND Long Covid neurology Source Type: blogs
Trial By Error: Dutch Study Links PEM in Long Covid to Biological Abnormalities
By David Tuller, DrPH A new study in Nature Communications, called “Muscle abnormalities worsen after post-exertional malaise in long COVID,” caused a stir after it was published last week. The investigators identified significant biological differences after an exercise challenge between long Covid (LC) patients with post-exertional malaise (PEM) and matched healthy controls who had recovered … Trial By Error: Dutch Study Links PEM in Long Covid to Biological Abnormalities Read More » (Source: virology blog)
Source: virology blog - January 10, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized Source Type: blogs
Trial By Error: An Interview with Journalist Ed Yong
By David Tuller, DrPH In the early months of the coronavirus pandemic, journalist Ed Yong played a key role in alerting the public to the wave of people suffering prolonged symptoms after an acute bout of COVID-19—the phenomenon that has come to be called long Covid. Yong, who won a Pulitzer Prize for his coronavirus … Trial By Error: An Interview with Journalist Ed Yong Read More » (Source: virology blog)
Source: virology blog - January 4, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized Ed Yong Long Covid The Atlantic Source Type: blogs
The Problem of Original Antigenic Sin
by Gertrud U. Rey Once the innate immune system senses a never-seen-before pathogen as new, it engages elements of the adaptive immune response. These adaptive immunity elements coordinate over time to develop a response that protects from re-infection and disease upon a second exposure to the same pathogen. The second exposure will immediately lead to … The Problem of Original Antigenic Sin Read More » (Source: virology blog)
Source: virology blog - January 4, 2024 Category: Virology Authors: Gertrud U. Rey Tags: Basic virology Gertrud Rey adaptive immunity antigenic imprinting antigenic seniority back-boosting H1N1 immunological imprinting influenza virus innate immunity negative interference original antigenic sin pandemic primary addic Source Type: blogs
Trial By Error: Update on NICE Response to “ Anomalies ” Paper; Higher ME/CFS Population Estimates in CDC Survey
By David Tuller, DrPH In July, the Journal of Neurology, Neurosurgery and Psychiatry published a “whine de coeur” called “Anomalies in the review process and interpretation of the evidence in the NICE guideline for chronic fatigue syndrome and myalgic encephalomyelitis.” The lead author was Professor Peter White, lead author of the discredited and arguably fraudulent … Trial By Error: Update on NICE Response to “Anomalies” Paper; Higher ME/CFS Population Estimates in CDC Survey Read More » (Source: virology blog)
Source: virology blog - January 3, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized anomalies CDC JNNP Source Type: blogs
Trial By Error: Disastrous Results for Professor Crawley ’ s Pediatric Online CBT Trial
By David Tuller, DrPH Pediatrician Esther Crawley, Bristol University’s methodologically and factually challenged grant magnet, has released what seem to be the first outcome results from her much-hyped but fatally flawed FITNET-NHS trial—and they are disastrous. The trial, a pediatric study of online CBT based on similar Dutch research that (falsely) claimed to have proven … Trial By Error: Disastrous Results for Professor Crawley’s Pediatric Online CBT Trial Read More » (Source: virology blog)
Source: virology blog - December 30, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized Crawley FITNET-NHS Source Type: blogs
Trial By Error: Julie Rehmeyer on the Heartbreaking Loss of Beth Mazur
By David Tuller, DrPH Beth Mazur was a long-time ME advocate and a co-founder of #MEAction. ME-world was shocked to learn on Friday–two days ago–that she was gone, at the unconscionably young age of 47. At the time, she was visiting New Mexico and Julie Rehmeyer, another patient and advocate. Words often fail at times … Trial By Error: Julie Rehmeyer on the Heartbreaking Loss of Beth Mazur Read More » (Source: virology blog)
Source: virology blog - December 25, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized Source Type: blogs
Trial By Error: Betsy Ladyzhets on New HHS Funding for Long Covid Clinics
By David Tuller, DrPH Investigative journalist Betsy Ladyzhets is a co-founder of The Sick Times, a new online publication covering long Covid and related disorders. Last week, she wrote about a new grant program for long Covid clinics from the U.S. Agency for Healthcare Research and Quality (AHRQ), part of the Department of Health and … Trial By Error: Betsy Ladyzhets on New HHS Funding for Long Covid Clinics Read More » (Source: virology blog)
Source: virology blog - December 23, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized ahrq Ladyzhets long covid clinics sick times Source Type: blogs
Trial By Error: #MEAction ’ s Jaime Seltzer on Recent NIH Gathering
By David Tuller, DrPH Last Tuesday and Wednesday (December 12th and 13th), the US National Institutes of Health–and, specifically, the National Institute of Allergy and Infectious Diseases–held a two-day meeting called “Advancing ME/CFS Research: Identifying Targets for Intervention and Learning from Long COVID.” In 2019, I’d physically attended a similar NIH gathering; this time, I … Trial By Error: #MEAction’s Jaime Seltzer on Recent NIH Gathering Read More » (Source: virology blog)
Source: virology blog - December 18, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized NIH Source Type: blogs
Trial By Error: Update on Our Letter Concerning the Prevalence of Functional Neurological Disorder
By David Tuller, DrPH In August, I submitted a letter to NeuroImage: Clinical concerning inflated rates of prevalence of functional neurological disorder, on behalf of myself and nine colleagues. After the letter went through peer review and a round of revisions, I was informed in early November that it had been accepted, as I noted … Trial By Error: Update on Our Letter Concerning the Prevalence of Functional Neurological Disorder Read More » (Source: virology blog)
Source: virology blog - December 11, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized FND functional neurological disorder neuroImage: clinical Perez prevalence Source Type: blogs
A Satellite Takes a Bite of Phage
by Gertrud U. Rey Satellite viruses lack one or more of the elements needed to replicate, and thus they depend on co-infection with a helper virus that can provide the missing components. In a well-known example of a satellite-helper system, Hepatitis D virus requires the presence of its helper Hepatitis B virus to make copies … A Satellite Takes a Bite of Phage Read More » (Source: virology blog)
Source: virology blog - December 7, 2023 Category: Virology Authors: Gertrud U. Rey Tags: Basic virology Gertrud Rey bacteriophage helper virus phage satellite plaque assay satellite virus satellite-helper system vampire virus Source Type: blogs
Trial By Error: Dutch Survey Respondents Rate GET/CBT as “ the Worst ” Approach, Per New Report
By David Tuller, DrPH A survey of more than 1500 patients in the Netherlands with a diagnosis of ME, CFS or ME/CFS rated graded exercise therapy as “the worst” interventions, according to an article on the site of the ME and Disability Support Group, while “explanation and advice about the importance of lying down to … Trial By Error: Dutch Survey Respondents Rate GET/CBT as “the Worst” Approach, Per New Report Read More » (Source: virology blog)
Source: virology blog - December 6, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized dutch Guidelines Knoop NICE survey Source Type: blogs
