The Problem of Original Antigenic Sin

by Gertrud U. Rey Once the innate immune system senses a never-seen-before pathogen as new, it engages elements of the adaptive immune response. These adaptive immunity elements coordinate over time to develop a response that protects from re-infection and disease upon a second exposure to the same pathogen. The second exposure will immediately lead to … The Problem of Original Antigenic Sin Read More ยป
Source: virology blog - Category: Virology Authors: Tags: Basic virology Gertrud Rey adaptive immunity antigenic imprinting antigenic seniority back-boosting H1N1 immunological imprinting influenza virus innate immunity negative interference original antigenic sin pandemic primary addic Source Type: blogs