Diving for Data
Discussion around this is definitely part of the public discourse now but this is going to turn slowly like an ocean liner as incentives become more aligned.“The reimbursement of volume-based agreements is such a complex calculation to unwind, and people acknowledge that it is sensible but a hard thing to do. It takes a lot to move people off tried-and-true, low-risk ways of measuring the performance of a drug.Related Content: Rid Yourself Of Dirty DataTalking The Same LanguageNavigating the ChaosSeeking the Holy Grail of RWEThe Naked Truth About Outcomes-Based PricingPrimary Event: Value Summit USA 2018Pr ...
Source: EyeForPharma - October 16, 2018 Category: Pharmaceuticals Authors: Andrew Stone Source Type: news

Space Oddities: Changing Microbiomes in the Final Frontier
(MedPage Today) -- A virologist-turned-astronaut's most interesting research may be outside the lab (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - October 4, 2018 Category: American Health Source Type: news

Janssen Reports Switching to SYMTUZA ™ Results in Maintained High Virologic Suppression and No Resistance Development up to 96-Weeks in Virologically Suppressed Adults with HIV-1
(Source: Johnson and Johnson)
Source: Johnson and Johnson - October 3, 2018 Category: Pharmaceuticals Source Type: news

Combination therapy targets latent reservoir of HIV
(Beth Israel Deaconess Medical Center) In a new study, Dan H. Barouch, MD, PhD, Director of the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center, and colleagues demonstrate that administering broadly neutralizing antibodies (bNAb) designed to target HIV in combination with agents that stimulate the innate immune system delayed viral rebound following discontinuation of ART in monkeys. The findings suggest that this two-pronged approach represents a potential strategy for targeting the viral reservoir. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - October 3, 2018 Category: Infectious Diseases Source Type: news

David A. Leib Named Chair of the Dept. of Microbiology & Immunology at the Geisel School of Medicine at Dartmouth
David A. Leib, PhD, has been named the Chair of the Department of Microbiology and Immunology at Dartmouth’s Geisel School of Medicine. Since joining Dartmouth in 2009, Leib has built a successful research program focusing on discovery and elucidation of new vaccines and therapeutics for neonatal herpesvirus infections. In addition to his research efforts, Leib also teaches undergraduate and graduate courses in virology at Dartmouth. (Source: News at Dartmouth Medical School)
Source: News at Dartmouth Medical School - September 19, 2018 Category: Hospital Management Authors: Derik Hertel Tags: Insider News Press Release Research chair David Leib faculty appointment Home-feature Microbiology and Immunology Source Type: news

Deadly disease monkeypox infects 10% of people who come into contact with sufferers
EXCLUSIVE A professor of virology at Brown University warned hospital staff are most at risk. Public Health England has confirmed a man has been diagnosed with the condition. (Source: the Mail online | Health)
Source: the Mail online | Health - September 10, 2018 Category: Consumer Health News Source Type: news

South Africa:SA Branch Chief At Us Centres for Disease Control Appears in Cape Town Court
[Daily Maverick] Zimbabwe-born US citizen, virologist and South African branch chief at the US Centres for Disease Control and Prevention, Dr Alfred Bere. (Photo from a social media profile) (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - September 4, 2018 Category: African Health Source Type: news

Inovio launches Ph1 study of Hep C vaccine
Inovio Pharmaceuticals (NSDQ:INO) and its partner, GeneOne Life Science (KSE:011000), said today that the companies have dosed the first patient in a Phase I study designed to test a preventive vaccine against hepatitis C infection. The companies plan to recruit 24 study participants to evaluate Inovio’s GLS-6150 candidate. Participants will include people who have a sustained virologic response following treatment for Hep. C, as well as healthy controls. They are slated to receive one of two doses of vaccine, administered intra-dermally and followed by electroporation with Inovio’s Cellectra device. Get t...
Source: Mass Device - September 4, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Clinical Trials Drug-Device Combinations Pharmaceuticals Wall Street Beat Inovio Pharmaceuticals Source Type: news

The reemergence of yellow fever
(Source: ScienceNOW)
Source: ScienceNOW - August 30, 2018 Category: Science Authors: Barrett, A. D. T. Tags: Virology perspective Source Type: news

Liver-Fibrosis Regression Seen After Hepatitis C Cure Liver-Fibrosis Regression Seen After Hepatitis C Cure
Liver fibrosis regresses in some patients with chronic hepatitis C infection who achieve a sustained virological response (SVR) to oral direct-acting antivirals (DAA), according to a retrospective study.Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - August 29, 2018 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Impact of SVR on Risk of T2DM Among HCV Patients in the US Impact of SVR on Risk of T2DM Among HCV Patients in the US
Does achieving sustained virologic response lower the risk for development of type 2 diabetes mellitus in patients with hepatitis C?Journal of Viral Hepatitis (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 28, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Ebola death toll in the Democratic Republic of Congo jumps to 55
Virologists have already warned the situation in the east of the country is ‘hard to control’ because the cases are in a conflict zone, roamed by armed militias. (Source: the Mail online | Health)
Source: the Mail online | Health - August 21, 2018 Category: Consumer Health News Source Type: news

The US Domestic Influenza Virologic Surveillance Landscape The US Domestic Influenza Virologic Surveillance Landscape
The development of a process map characterizing the landscape of US influenza virologic surveillance may help improve pandemic planning and response efforts.Emerging Infectious Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 15, 2018 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news

UC Davis researchers find quiet viruses alter body's response to vaccines, pathogens
(University of California - Davis Health System) UC Davis researchers have shown that low levels of cytomegalovirus (CMV) have a significant impact on microbe and immune cell populations and how the immune system responds to the influenza vaccine. The study was published in the Journal of Virology. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 3, 2018 Category: International Medicine & Public Health Source Type: news

Nigeria:Plateau Virology Research Centre Gets Rare International Accreditation
[This Day] Jos -The Plateau State Human Virology Research Centre (PLASVIREC) laboratory has gotten international accreditation from the International Standards Organisation (ISO) in recognition of its standard medical laboratory science practices and procedures. PLASVIREC was initiated for the implementation of HIV surveillance, research, testing, and prevention activities in Nigeria, as well as Early Infant Diagnosis, molecular techniques, clinical trials, cohort studies and provision of technical support/training. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 2, 2018 Category: African Health Source Type: news

'Ending AIDS movement falters worldwide
(Source: ScienceNOW)
Source: ScienceNOW - August 2, 2018 Category: Science Authors: Cohen, J. Tags: Epidemiology, Medicine, Diseases, Virology In Depth Source Type: news

Active substance raises hopes of curing hepatitis E
(Ruhr-University Bochum) An international team of researchers has now found a possible active substance against the virus in the naturally occurring substance silvestrol. The substance inhibited the replication of pathogens both in cell culture and in the mouse model. The researchers led by Dr Daniel Todt and Prof Dr Eike Steinmann from the Department of Medical and Molecular Virology at Ruhr-Universit ä t Bochum (RUB) reported in the journal " Antiviral Research " on 23 July 2018. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 1, 2018 Category: International Medicine & Public Health Source Type: news

Benefits of early antiretroviral therapy in HIV-infected children
(Institut Pasteur) The initial findings of the ANRS CLEAC study coordinated by Pierre Frange (H ô pital Necker -- AP-HP), help define the immunological and virological benefits of early antiretroviral therapy in HIV-infected children living in France. The results of this study will be presented by Florence Buseyne (Oncogenic Virus Epidemiology& Pathophysiology Team -- Institut Pasteur) this Wednesday, July 25 at the 22nd International AIDS Conference (AIDS 2018) being held in Amsterdam from July 23 to 26, 2018. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 25, 2018 Category: Biology Source Type: news

Congo rapidly curtails Ebola
(Source: ScienceNOW)
Source: ScienceNOW - July 19, 2018 Category: Science Authors: Cohen, J. Tags: Epidemiology, Medicine, Diseases, Virology In Depth Source Type: news

FDA Approves Symtuza for Treatment of HIV FDA Approves Symtuza for Treatment of HIV
The FDA has approved the first protease inhibitor-based single-tablet regimen for the treatment of HIV-1 infection in treatment-naive and certain virologically suppressed adult patients.FDA Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 18, 2018 Category: Consumer Health News Tags: HIV/AIDS News Alert Source Type: news

Fixed-Dose Bictegravir-Emtricitabine-Tenofovir Maintains Virologic Suppression in HIV Fixed-Dose Bictegravir-Emtricitabine-Tenofovir Maintains Virologic Suppression in HIV
Fixed-dose bictegravir-emtricitabine-tenofovir (Biktarvy) maintains virologic suppression in adults with HIV-1 who are switched from dolutegravir-abacavir-lamivudine or from boosted protease inhibitor-based regimens, according to results from two noninferiority trials.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 13, 2018 Category: Consumer Health News Tags: HIV/AIDS News Source Type: news

Thermo Scientific Krios Cryo-TEM instrument installed at the Institut Pasteur
(Institut Pasteur) The Institut Pasteur officially unveiled its new Thermo Scientific Krios Cryo-TEM electron microscope at an event in Paris, France, on July 12, 2018. The availability of one of the most powerful microscopes in the world in the center of Paris will allow structural biologists to extend their research in areas such as immunology, bacteriology, virology, parasitology and neuroscience.By acquiring the Krios Cryo-TEM system, the Institut Pasteur is offering its scientists a closer look at life. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 13, 2018 Category: International Medicine & Public Health Source Type: news

Polio outbreaks in the DRC threaten eradication effort
(Source: ScienceNOW)
Source: ScienceNOW - July 5, 2018 Category: Science Authors: Roberts, L. Tags: Epidemiology, Medicine, Diseases, Virology In Depth Source Type: news

Nigeria:Why Nigeria Cannot Start Producing Vaccines Now - Professor of Virology
[Premium Times] Oyewale Tomori is a professor of virology, educational administrator and former vice chancellor. He is a fellow of the Academy of Science of Nigeria, fellow of the College of Veterinary Surgeons of Nigeria and fellow of the Royal College of Pathologists of the United Kingdom. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - July 3, 2018 Category: African Health Source Type: news

Nigeria:Healthcare Experts Canvass Blood Donation to Save Lives
[Guardian] Abuja, Damaturu, Lagos -As Nigeria joins in marking World Blood Donor Day, the Institute of Human Virology, Nigeria (IHVN) has implored people to donate voluntarily to save lives. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - June 14, 2018 Category: African Health Source Type: news

Ebola outbreak in the DRC that has 'killed 25 people' has the 'potential for rapid expansion'
Dr Derek Gatherer, a virologist from Lancaster University, warns the fresh outbreak - which began in Bikoro - is ‘reminiscent’ of the 2014 Ebola pandemic, which decimated West Africa. (Source: the Mail online | Health)
Source: the Mail online | Health - May 31, 2018 Category: Consumer Health News Source Type: news

Nipah virus - India
On 19 May 2018, three deaths due to Nipah virus infection were reported in Kozhikode District, Kerala State, India. The three deaths occurred in a family cluster and a fourth death was subsequently reported in a health care worker who was involved in treatment of the family in the local hospital. Laboratory testing of throat swabs, urine and blood samples collected from four suspected patients has been conducted by the National Institute of Virology in Pune; three of the four reported deaths were confirmed positive for Nipah virus (NiV) by real-time polymerase chain reaction (RT-PCR) and IgM Elisa for NiV. (Source: WHO Disease Outbreaks)
Source: WHO Disease Outbreaks - May 31, 2018 Category: Infectious Diseases Tags: news Source Type: news

Liver Stiffness, Steatosis in HCV Patients With SVR on DAAs Liver Stiffness, Steatosis in HCV Patients With SVR on DAAs
This study evaluated changes in liver stiffness and steatosis in patients with HCV who received direct-acting anti-viral therapy and achieved sustained virological response.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 29, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

400-million-year-old evolutionary arms race helps researchers understand HIV
(University of Western Ontario) Researchers at Western University were interested in the origin of a gene that encodes for protein, HERC5, shown to potently inhibit HIV. In a new study published in the Journal of Virology, Stephen Barr, Ph.D., assistant professor at Western's Schulich School of Medicine& Dentistry, shows that the gene first emerged in fish over 400 million years ago and has been involved in an evolutionary arms race with viruses ever since. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 24, 2018 Category: International Medicine & Public Health Source Type: news

A call to arms against the other retrovirus
(Source: ScienceNOW)
Source: ScienceNOW - May 24, 2018 Category: Science Authors: Kupferschmidt, K. Tags: Epidemiology, Medicine, Diseases, Virology In Depth Source Type: news

Vaccine trial launched to stop Ebola
(Source: ScienceNOW)
Source: ScienceNOW - May 17, 2018 Category: Science Authors: Cohen, J. Tags: Epidemiology, Medicine, Diseases, Virology In Depth Source Type: news

Next-generation diagnostics with CRISPR
(Source: ScienceNOW)
Source: ScienceNOW - April 26, 2018 Category: Science Authors: Chertow, D. S. Tags: Virology perspective Source Type: news

Nigeria:No Lassa Fever Vaccine Anywhere in the World - Virologist
[Guardian] Enugu -A Virologist, Prof Simeon Magaji Agwale, yesterday, insisted that there is no certified vaccine for the treatment of Lassa Fever anywhere in the world, stressing that Nigeria was best suited to develop vaccines for the cure of the disease for the rest of the world. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - April 14, 2018 Category: African Health Source Type: news

Hepatitis C Symptoms Can Persist After Cure (CME/CE)
(MedPage Today) -- Cryoglobulins observed 2 years after sustained virologic response (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - April 13, 2018 Category: Gastroenterology Source Type: news

Sustained virological response to oral hepatitis C virus treatment associated with reduced mortality in an Italian cohort
(European Association for the Study of the Liver) A large-scale, real-world data on the course of liver disease after clearance of HCV with direct-acting antiviral agents show reduced risk of death at all stages of disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 13, 2018 Category: International Medicine & Public Health Source Type: news

Screening for hepatocellular carcinoma in patients with hepatitis C-related cirrhosis achieving sustained virological response is likely to be cost effective
(European Association for the Study of the Liver) A Canadian study suggests that biannual or annual ultrasound screening for HCC is likely to be cost effective after a sustained virological response in those with hepatitis C-related cirrhosis, but not in those with advanced fibrosis without cirrhosis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 12, 2018 Category: Cancer & Oncology Source Type: news

Vaginal Delivery OK With Well Controlled HIV, Study Confirms Vaginal Delivery OK With Well Controlled HIV, Study Confirms
Most women living with HIV can achieve good virological control and deliver their children vaginally, according to a study of national data from Finland.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 10, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

A delicate balance
(Source: ScienceNOW)
Source: ScienceNOW - April 5, 2018 Category: Science Authors: Broadfoot, M. Tags: Development, Immunology, Virology Feature Source Type: news

New coronavirus emerges from bats in China, devastates young swine
(NIH/National Institute of Allergy and Infectious Diseases) A newly identified coronavirus that killed nearly 25,000 piglets in 2016-17 in China emerged from horseshoe bats near the origin of the severe acute respiratory syndrome coronavirus (SARS-CoV), which emerged in 2002 in the same bat species. The new virus, called swine acute diarrhea syndrome coronavirus (SADS-CoV), doesn't appear to infect people, unlike SARS-CoV. The NIAID-funded work was a collaboration among scientists from EcoHealth Alliance, Duke-NUS Medical School, Wuhan Institute of Virology and other organizations. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 4, 2018 Category: Infectious Diseases Source Type: news

New CDC Director Named
Dr. Robert Redfield has been named the new director for the U.S. Centers for Disease Control and Prevention (CDC) by Secretary of Health and Human Services Alex Azar. The position does not require Senate confirmation. The announcement came on March 21, 2018, a couple of months after former CDC Director Brenda Fitzgerald resigned from the position because of her myriad conflicts of interest arising from her failure to divest from investments in tobacco and healthcare companies. Redfield, a virologist and professor at the University of Maryland School of Medicine, has an extensive background in HIV/AIDS research. He manages...
Source: Public Policy Reports - April 2, 2018 Category: Biology Authors: AIBS Source Type: news

Janssen Announces Positive CHMP Opinion for JULUCATM ▼ (dolutegravir/rilpivirine)
If approved, stable, virologically suppressed adults living with HIV-1 could have the option to switch to a single-pill, two-drug regimen (Source: Johnson and Johnson)
Source: Johnson and Johnson - March 23, 2018 Category: Pharmaceuticals Source Type: news

AIDS Researcher Robert Redfield Is the New CDC Director. Here ’s Why the Pick Is Controversial
The Trump administration has tapped HIV researcher Dr. Robert Redfield to be the new leader of the U.S. Centers for Disease Control and Prevention (CDC), Redfield will be replacing Dr. Brenda Fitzgerald, who stepped down from CDC director after Politico reported that she had bought shares in a tobacco company after accepting the position. Redfield will not require Senate confirmation. However, reactions to his selection have been mixed. Before joining the CDC, Redfield was a professor at the University of Maryland School of Medicine and the co-founder of the university’s Institute of Human Virology. Over his career, ...
Source: TIME: Health - March 22, 2018 Category: Consumer Health News Authors: Alexandra Sifferlin Tags: Uncategorized CDC CDC Director Dr. Robert Redfield healthytime public health Scientific misconduct Source Type: news

Longtime AIDS researcher Robert Redfield picked to lead CDC
A leading AIDS researcher, who is well respected for his clinical work but has no experience running a governmental public-health agency, was named Wednesday to head the Centers for Disease Control and Prevention. Health and Human Services Secretary Alex Azar said in a statement that the 66-year-old virologist and physicians has “dedicated his entire life […]Related:Former FDA commissioners say right-to-try bills could endanger ‘vulnerable patients’Top candidate to lead CDC is an HIV/AIDS researcher5 interesting findings about U.S. abortions from a new report on the current science (Source: Washing...
Source: Washington Post: To Your Health - March 21, 2018 Category: Consumer Health News Source Type: news

AIDS Researcher Top Candidate to Lead the C.D.C.
The administration is vetting Dr. Robert Redfield, a founder of the University of Maryland ’ s Institute of Human Virology, for C.D.C. chief. (Source: NYT Health)
Source: NYT Health - March 17, 2018 Category: Consumer Health News Authors: SHEILA KAPLAN Tags: Dr. Robert Redfield Appointments and Executive Changes Centers for Disease Control and Prevention University of Maryland Source Type: news

Nigeria hit by unprecedented Lassa fever outbreak
(Source: ScienceNOW)
Source: ScienceNOW - March 15, 2018 Category: Science Authors: Roberts, L. Tags: Epidemiology, Medicine, Diseases, Virology In Depth Source Type: news

Concern as HIV prevention strategy languishes
(Source: ScienceNOW)
Source: ScienceNOW - March 15, 2018 Category: Science Authors: Cohen, J. Tags: Epidemiology, Medicine, Diseases, Virology In Depth Source Type: news

ART: Measuring Tx Adherence by a Hair (CME/CE)
(MedPage Today) -- Antiretroviral levels in hair linked with virologic outcomes (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - March 6, 2018 Category: Infectious Diseases Source Type: news

Nature's strategies: Stealing genes to survive
(Source: ScienceNOW)
Source: ScienceNOW - March 1, 2018 Category: Science Authors: Leslie, M. Tags: Virology Feature Source Type: news

How bats carry viruses without getting sick
(Cell Press) Bats are known to harbor highly pathogenic viruses like Ebola or Marburg and yet they do not show clinical signs of disease. In a paper published in the journal Cell Host& Microbe on February 22, scientists at the Wuhan Institute of Virology in China find that in bats, an antiviral immune pathway called the STING-interferon pathway is dampened, and bats can maintain just enough defense against illness without triggering a heightened immune reaction. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 22, 2018 Category: Infectious Diseases Source Type: news

These Are the Dirtiest Places in Your Hotel Room
You may want to pack some disinfectant wipes the next time you travel. When you stay in a hotel room, you usually expect that staff have cleaned it thoroughly after the last guest stayed there. But this is not always the case, and even regular cleaning can leave travelers open to other people’s germs, experts say. In one 2012 study presented at the general meeting of the American Society of Microbiology, 81% of surfaces sampled had some fecal bacteria. Researchers found that light switches and TV remotes were among the objects most heavily contaminated with bacteria, and toilets and bathroom sinks also had high level...
Source: TIME: Health - February 13, 2018 Category: Consumer Health News Authors: Abigail Abrams Tags: Uncategorized Germs healthytime onetimetravel Source Type: news