Better Together: How Cross-Agency Data Sharing Can Improve the Care Continuum for People Living with HIV/AIDS
Georgia has leveraged an existing data use agreement (DUA) to gather data across agencies and is using that data to target key improvements to improve rates of virologic suppression in HIV-infected, Medicaid beneficiaries. (Source: PHPartners.org)
Source: PHPartners.org - October 31, 2017 Category: International Medicine & Public Health Source Type: news

Single-tablet Switch Option Effective in Virologically Suppressed HIV Single-tablet Switch Option Effective in Virologically Suppressed HIV
A new single-tablet regimen (STR) that includes the protease inhibitor (PI) darunavir, cobicistat, emtricitabine, and tenofovir alafenamide maintains viral suppression in adults infected with HIV-1, according to results from the EMERALD phase 3 noninferiority trial.Reuters Health Information (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - October 20, 2017 Category: Infectious Diseases Tags: HIV/AIDS News Source Type: news

Glecaprevir-Pibrentasvir Effective in Patients With HCV, CKD Glecaprevir-Pibrentasvir Effective in Patients With HCV, CKD
Glecaprevir-pibrentasvir produced high sustained virologic response rates regardless of the underlying HCV genotype in patients with severe chronic kidney disease and HCV infection, a study found.Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 16, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Sustained Response with HCV Combo Drug in CKD
(MedPage Today) -- Patients with both diseases had virologic response and no failure (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - October 12, 2017 Category: Gastroenterology Source Type: news

Investigational Flu Drug a Near Match for Oseltamivir
(MedPage Today) -- Clinical outcomes'identical'but virology different (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - October 8, 2017 Category: Primary Care Source Type: news

Broadly neutralizing antibodies to prevent HIV-1
(Source: ScienceNOW)
Source: ScienceNOW - October 5, 2017 Category: Science Authors: Cohen, M. S., Corey, L. Tags: Immunology, Medicine, Diseases, Virology perspective Source Type: news

Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques
The development of an effective AIDS vaccine has been challenging because of viral genetic diversity and the difficulty of generating broadly neutralizing antibodies (bnAbs). We engineered trispecific antibodies (Abs) that allow a single molecule to interact with three independent HIV-1 envelope determinants: the CD4 binding site, the membrane-proximal external region (MPER), and the V1V2 glycan site. Trispecific Abs exhibited higher potency and breadth than any previously described single bnAb, showed pharmacokinetics similar to those of human bnAbs, and conferred complete immunity against a mixture of simian-human immuno...
Source: ScienceNOW - October 5, 2017 Category: Science Authors: Xu, L., Pegu, A., Rao, E., Doria-Rose, N., Beninga, J., McKee, K., Lord, D. M., Wei, R. R., Deng, G., Louder, M., Schmidt, S. D., Mankoff, Z., Wu, L., Asokan, M., Beil, C., Lange, C., Leuschner, W. D., Kruip, J., Sendak, R., Do Kwon, Y., Zhou, T., Chen, X Tags: Immunology, Medicine, Diseases, Virology r-articles Source Type: news

Male hormones may promote infection by virus that causes Kaposi's sarcoma
(PLOS) Male hormones may facilitate infection with a virus that can cause a type of cancer known as Kaposi's sarcoma. This finding, published in PLOS Pathogens by Ke Lan's group of the State Key Laboratory of Virology, Wuhan University, China, could help explain why men have an increased risk of developing Kaposi's sarcoma. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 28, 2017 Category: Infectious Diseases Source Type: news

Why is the flu vaccine so mediocre?
(Source: ScienceNOW)
Source: ScienceNOW - September 21, 2017 Category: Science Authors: Cohen, J. Tags: Immunology, Medicine, Diseases, Pharmacology, Toxicology, Virology In Depth Source Type: news

Hepatitis E: Virology, Epidemiology, Presentation and Therapy Hepatitis E: Virology, Epidemiology, Presentation and Therapy
What is our current understanding of the molecular biology of hepatitis E? Review diagnostic and therapeutic strategies and examine future directions for clinical research in this overview.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 17, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Where has all the Zika gone?
(Source: ScienceNOW)
Source: ScienceNOW - August 17, 2017 Category: Science Authors: Cohen, J. Tags: Epidemiology, Virology In Depth Source Type: news

On the trail of yellow fever
(Source: ScienceNOW)
Source: ScienceNOW - August 17, 2017 Category: Science Authors: Kean, S. Tags: Epidemiology, Pharmacology, Toxicology, Virology Feature Source Type: news

Newly Approved Hepatitis C Drug Has High Response Rates (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM Nearly all patients with chronic hepatitis C virus (HCV) infection treated with glecaprevir-pibrentasvir achieved sustained virologic response after 12 weeks … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - August 16, 2017 Category: Primary Care Source Type: news

Einstein Researchers Awarded Three NIH Grants Totaling $12 Million to Fight Virulent Viruses
August 11, 2017—BRONX, NY—The NIH has awarded Einstein researchers three grants totaling more than $12 million to protect against three deadly viruses—Ebola, Marburg and hantavirus. Research collaborations betweenKartik Chandran, Ph.D., professor of microbiology& immunology and the Harold and Muriel Block Faculty Scholar in Virology, andJonathan Lai, Ph.D., associate professor of biochemistry, have led to novel approaches for developing vaccines and treatments. (Source: Einstein News)
Source: Einstein News - August 11, 2017 Category: Universities & Medical Training Source Type: news

Einstein researchers awarded 3 NIH grants totaling $12 million to fight virulent viruses
(Albert Einstein College of Medicine) The NIH has awarded Einstein researchers three grants totaling more than $12 million to protect against three deadly viruses -- Ebola, Marburg and hantavirus. Research collaborations between Kartik Chandran, Ph.D., professor of microbiology& immunology and the Harold and Muriel Block Faculty Scholar in Virology, and Jonathan Lai, Ph.D. associate professor of biochemistry, have led to novel approaches for developing vaccines and treatments. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 11, 2017 Category: International Medicine & Public Health Source Type: news

Study Tracks Gender Ratios at Conferences
While men make up the majority of invited speakers at four major virology conferences, recent trends demonstrate a greater inclusion of women. (Source: The Scientist)
Source: The Scientist - July 31, 2017 Category: Science Tags: Daily News,News & Opinion,The Scientist Source Type: news

Should we be worried about hepatitis E?
(Stellenbosch University) Hepatitis E gets little press compared to its better-known cousins A, B and C, but Stellenbosch University virologists say we should wake up to how transmission of this virus is changing. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 27, 2017 Category: Infectious Diseases Source Type: news

Disease sleuths unmask deadly encephalitis culprit
(Source: ScienceNOW)
Source: ScienceNOW - July 27, 2017 Category: Science Authors: Pulla, P. Tags: Asia/Pacific News, Epidemiology, Medicine, Diseases, Virology In Depth Source Type: news

Zika rewrites maternal immunization ethics
(Source: ScienceNOW)
Source: ScienceNOW - July 20, 2017 Category: Science Authors: Cohen, J. Tags: Medicine, Diseases, Pharmacology, Toxicology, Science and Policy, Virology In Depth Source Type: news

Labmade smallpox is possible, study shows
(Source: ScienceNOW)
Source: ScienceNOW - July 13, 2017 Category: Science Authors: Kupferschmidt, K. Tags: Pharmacology, Toxicology, Science and Policy, Virology In Depth Source Type: news

New York City rats provide a gift to virologists
(Source: ScienceNOW)
Source: ScienceNOW - July 13, 2017 Category: Science Authors: Kiberstis, P. A. Tags: Immunology, Microbiology twis Source Type: news

Virological Testing for Early Infant HIV Diagnosis Virological Testing for Early Infant HIV Diagnosis
How accurate are virological assays for the diagnosis of HIV infection in infants?JAIDS: Journal of Acquired Immune Deficiency Syndromes (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 12, 2017 Category: Consumer Health News Tags: HIV/AIDS Journal Article Source Type: news

Sustained Response to Direct-acting HCV Antivirals Tied to Lower HCC Risk Sustained Response to Direct-acting HCV Antivirals Tied to Lower HCC Risk
A sustained virologic response to direct-acting antiviral treatment of hepatitis C (HCV) is associated with a “ considerable ” reduction in the risk of hepatocellular carcinoma (HCC), researchers say.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 3, 2017 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Sequential Sterilization of Simple Effluent Biowaste Streams
The AutoFlow SINK was designed for small laboratory applications such as research, virology, vaccines, and genetically modified organisms (GMO) in contract research organisations (CMO), hospitals, clinics, isolation units, and mobile laboratories. (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - June 24, 2017 Category: Pharmaceuticals Source Type: news

By far, men garner most coveted speaking slots at virology meetings
(University of Wisconsin-Madison) In their recent study, published in the Journal of Virology, the University of Wisconsin-Madison researchers examined 35 years worth of invited speaker rosters from four prominent virology meetings, including the American Society for Virology, which is hosting its annual meeting in Madison, Wisconsin starting June 24, 2017. They found that men were overwhelmingly represented. For example, between 1982 and 2017, 77 percent of the speakers at ASV's annual meetings were male. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 23, 2017 Category: Biology Source Type: news

Hologic Announces FDA Clearance of Aptima(R) Assay to Detect Herpes Simplex Virus 1 and 2
Aptima HSV 1 & 2 Assay Now Available Alongside Women's Health, Virology Menu on the Fully Automated Panther System MARLBOROUGH, Mass. , June 20, 2017 -- (Healthcare Sales & Marketing Network) -- Hologic, Inc. (Nasdaq: HOLX) announced today that it has ... Diagnostics, FDA Hologic, Aptima, Herpes Simplex Virus, Panther (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - June 20, 2017 Category: Pharmaceuticals Source Type: news

Antiviral therapy is effective in fighting hepatitis C | Letters
The Cochrane analysis casting doubt on this life-saving therapy is flawed and may deter patients from seeking it, say clinicians and scientistsWe are clinicians and scientists who have studied and treated patients with chronic hepatitis C virus infection over many years and patient groups that represent those affected by hepatitis C. We write in response to your article on the effectiveness of antiviral therapy (Hepatitis ‘wonder drug’ may be clinically ineffective, say experts, 9 June). The Cochrane review that you highlight analysed clinical trials, which are by nature short term, where the sole purpose was t...
Source: Guardian Unlimited Science - June 13, 2017 Category: Science Authors: Letters Tags: Hepatitis C Health Pharmaceuticals industry Medical research Drugs Business Science UK news Society Source Type: news

Efficacy and Safety After Switching From TDF to TAF in HIV Efficacy and Safety After Switching From TDF to TAF in HIV
What benefits might tenofovir alafenamide offer virologically suppressed HIV patients over tenofovir disoproxil fumarate?JAIDS: Journal of Acquired Immune Deficiency Syndromes (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 12, 2017 Category: Consumer Health News Tags: HIV/AIDS Journal Article Source Type: news

Tulane researchers help find possible explanation for unparalleled spread of Ebola virus
(Tulane University) The world may be closer to knowing why Ebola spreads so easily thanks to a team of researchers from Tulane University and other leading institutions who discovered a new biological activity in a small protein from the deadly virus. The team's findings were recently published in the Journal of Virology. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 6, 2017 Category: Infectious Diseases Source Type: news

When DAA Treatment for Hepatitis C Fails, 3-Drug Regimen " Highly Effective " (FREE)
By Kelly Young Edited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, DFASAM The combination of sofosbuvir, velpatasvir, and voxilaprevir is effective for hepatitis C in patients with virologic failure after direct-acting antiviral agent (DAA) treatment, according to two phase 3, industry-funded trials in the … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - June 1, 2017 Category: Primary Care Source Type: news

Bat patrol
(Source: ScienceNOW)
Source: ScienceNOW - June 1, 2017 Category: Science Authors: Kupferschmidt, K. Tags: Epidemiology, Virology Feature Source Type: news

Sequential Batch Sterilization of Simple Biowaste Streams
The AutoFlow SB is designed for laboratory applications such as research, virology, vaccine, and genetically modified organisms (GMO) in contract manufacturing organisation (CMO), forensic, hospitals, clinics, isolation units, and mobile laboratories … (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - May 31, 2017 Category: Pharmaceuticals Source Type: news

Refractory HCV Responds Well to Three-Drug Combo Refractory HCV Responds Well to Three-Drug Combo
Sofosbuvir-velpatasvir-voxilaprevir therapy resulted in a 98% sustained virologic response in patients with refractory HCV vs 90% for a two-drug regimen of sofosbuvir-velpatasvir.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 31, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

HIV: A therapeutic advance for resource-limited settings
(ANRS) ANRS 12286 MOBIDIP, a clinical trial running in parallel in three countries in sub-Saharan Africa, shows that dual therapy with lamivudine and a boosted protease inhibitor is effective as second-line treatment in patients infected by HIV with multiple mutations. Such treatment deescalation will reduce costs, side effects, and the need for virological monitoring of patients. The results of this study are published in The Lancet HIV. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - May 29, 2017 Category: Infectious Diseases Source Type: news

Nigeria: Nigeria Not Prepared for Another Ebola Outbreak - Tomori
[Guardian] Contrary to assertion by the Nigeria Centre for Disease Control (NCDC) that the country is better prepared for another possible outbreak of Ebola Virus Disease (EVD) now than in 2014, a virologist, Prof. Oyewale Tomori, said Nigeria is not prepared for another outbreak. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - May 26, 2017 Category: African Health Source Type: news

Virologic Monitoring of Poliovirus Type 2 after Oral Poliovirus Vaccine Type 2 Withdrawal in April 2016 — Worldwide, 2016–2017
(Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - May 25, 2017 Category: American Health Source Type: news

Continuous Flow Sterilization of Simple Biowaste Streams
PRI Bio's AutoFlow is designed for applications in biologics, virology, vaccine, genetically modified organism (GMO), and contract manufacturing organization (CMO) pilot plant research labs through large-scale manufacturing facilities. (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - May 25, 2017 Category: Pharmaceuticals Source Type: news

New Ebola outbreak rings alarm bells early
(Source: ScienceNOW)
Source: ScienceNOW - May 25, 2017 Category: Science Authors: Cohen, J. Tags: Epidemiology, Immunology, Pharmacology, Toxicology, Virology In Depth Source Type: news

FGCU virologists publish study that finds Zika invaded Florida multiple times in 2016
(Florida Gulf Coast University) A new study by an international group of scientists reveals that the Zika virus outbreak in Florida wasn't a single virus introduction but rather at least four separate introductions from the Caribbean and Central America that each led to local chains of transmission. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - May 24, 2017 Category: Infectious Diseases Source Type: news

Influenza Pandemic Preparedness and Response in Ambulatory Settings
Joint Commission. 05/04/2017 This online course covers how to effectively respond in the face of a pandemic, and how to develop an influenza pandemic preparedness and response plan following a four-step guide. It discusses how to differentiate the virologic, epidemiologic, and clinical features of pandemic influenza from seasonal influenza; and how laboratory testing and diagnosis, patient management and treatment, and team training are essential. (Text) Site requires free registration. (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - May 15, 2017 Category: International Medicine & Public Health Authors: The U.S. National Library of Medicine Source Type: news

Martin Allday obituary
My friend and colleague Martin Allday, who has died aged 66 of cancer, was a professor atImperial College London with an international reputation as a molecular virologist.His field was the biology of theEpstein-Barr virus and his research revealed completely new insights into its link with cancer. The question that fascinated him and that he researched for 30 years was how this extremely common, generally harmless virus caused the disease.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - May 8, 2017 Category: Science Authors: Dorothy Crawford Tags: Medical research Science Cancer Imperial College London Source Type: news

Gene Variation Predicts Recovery in Decompensated Hep C Gene Variation Predicts Recovery in Decompensated Hep C
Genetic differences that are associated with recovery in patients with hepatitis C and decompensated cirrhosis who achieve a sustained virologic response could someday guide liver transplantation.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 7, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Generic Direct-Acting Antivirals Effective in Hep C Generic Direct-Acting Antivirals Effective in Hep C
Patients with hepatitis C experience a sustained virologic response with generic direct-acting antivirals, a new study shows, but availability remains an issue.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 2, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Multiclass HCV Resistance to DAA Failure Multiclass HCV Resistance to DAA Failure
This study aimed to define the pattern of clinically relevant resistance-associated substitutions associated with real-life DAA virological failures.Liver International (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - May 2, 2017 Category: Transplant Surgery Tags: Gastroenterology Journal Article Source Type: news

Combo Drug Beats Tough-to-Treat HCV Genotype 3 (CME/CE)
(MedPage Today) -- Anti-viral led to sustained virological response in 95% of trial patients (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - April 24, 2017 Category: Gastroenterology Source Type: news

Pitavastatin an Option for High LDL-C With Antiretrovirals for HIV Pitavastatin an Option for High LDL-C With Antiretrovirals for HIV
It seemed more potent against LDL than pravastatin in a small trial; other statins may interfere with some anti-HIV drugs. Virologic failure or serious adverse events weren't seen with either statin.Heartwire from Medscape (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - April 24, 2017 Category: Cardiology Tags: Cardiology News Source Type: news

Meet the Scientists Running for Office
Science doesn’t have opinions — and it’s not especially interested in any that you’ve got either. Science does have hypotheses, and it does have data and it does run a whole lot of experiments to get still more data. And then it has results. You may or may not like the results, but if the work has been done right, you don’t get to deny them. In an era in which facts must wrestle with “alternative facts,” that is a memo that fewer and fewer elected officials seem to have gotten — or at least they haven’t read it. For every researcher studying childhood development who c...
Source: TIME: Top Science and Health Stories - April 22, 2017 Category: Science Authors: Jeffrey Kluger Tags: Uncategorized Source Type: news

Merck Announces New Phase 2 Data on Investigational Triple Combination Therapy MK-3682B for Chronic Hepatitis C
Dateline City: KENILWORTH, N.J. Findings Presented at The International Liver Congress ™ 2017 Show High Rates of Sustained Virologic Response (SVR12) in Genotype 1 Patients for Whom Direct-Acting Antiviral Therapy Had Previously FailedKENILWORTH, N.J.--(BUSINESS WIRE)--Merck (NYSE: MRK), known as MSD outside of the United States and Canada, today announced the first sustained virologic response1 (SVR) results 12 weeks after completion of therapy (SVR12, considered virologic cure) fromC-SURGE, an ongoing, open label Phase 2 clinical trial evaluating MK-3682B [uprifosbuvir (MK-3682)2/grazoprevir3...
Source: Merck.com - Research and Development News - April 22, 2017 Category: Pharmaceuticals Tags: Research and Development News Corporate News Latest News #Merck #MRK $MRK Hepatitis C MSD NYSE:MRK Source Type: news

Henrietta Lacks' Cells Are Still Helping Protect Women From Cervical Cancer
When Henrietta Lacks was being treated for cervical cancer more than 60 years ago, her cells were taken for medical research without her consent. This ethical controversy became the subject of a 2010 best-selling book, Rebecca Skloot’s The Immortal Life Of Henrietta Lacks, and now an HBO movie of the same name starring Oprah Winfrey. Despite radiation therapy and surgery, Lacks died from the cancer in 1951. But her cells, known to scientists as HeLa cells, have played a role in many scientific advancements ― and have helped protect other young women from the cervical cancer that took Lacks’ lif...
Source: Healthy Living - The Huffington Post - April 21, 2017 Category: Consumer Health News Source Type: news