Log in to search using one of your social media accounts:

 

Influenza Pandemics of 1918 and 2009Influenza Pandemics of 1918 and 2009
Studying the similar features of the 1918 and 2009 influenza pandemics may provide better control of influenza pandemics in the future. Future Virology (Source: Medscape PublicHealth Headlines)
Source: Medscape PublicHealth Headlines - April 29, 2013 Category: Primary Care Tags: Infectious Diseases Journal Article Source Type: news

Oral Regimen Sustains Hepatitis C Viral Response to 24 WeeksOral Regimen Sustains Hepatitis C Viral Response to 24 Weeks
A regimen of 3 oral direct-acting antiviral drugs plus ribavirin produced sustained virologic responses above 90% in a broad range of patients infected with hepatitis C. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 25, 2013 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Simeprevir Administered Once Daily Demonstrates Sustained Virologic Response In Genotype 1 Chronic Hepatitis C Patients, Studies Find
Janssen R&D Ireland (Janssen) have announced primary efficacy and safety results from two global Phase 3 studies demonstrating that use of the investigational protease inhibitor simeprevir (TMC435) led to sustained virologic response 12 weeks after the end of treatment (SVR12) in 80 and 81 percent, respectively, of treatment-naïve genotype 1 chronic hepatitis C adult patients with compensated liver disease, including all stages of liver fibrosis, when administered once daily with pegylated interferon and ribavirin... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 25, 2013 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

Vesicular Stomatitis Virus Kills Melanoma In Animal Model, Spares Normal Cells
Researchers from Yale University School of Medicine have demonstrated that vesicular stomatitis virus (VSV) is highly competent at finding, infecting, and killing human melanoma cells, both in vitro and in animal models, while having little propensity to infect non-cancerous cells. "If it works as well in humans, this could confer a substantial benefit on patients afflicted with this deadly disease," says Anthony van den Pol, a researcher on the study. The research was published online ahead of print in the Journal of Virology... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 25, 2013 Category: Consumer Health News Tags: Melanoma / Skin Cancer Source Type: news

Food and Environmental Virology adds society affiliation
(Springer) Springer's journal Food and Environmental Virology is now the official publication of the International Society for Food and Environmental Virology. The new affiliation takes effect immediately. The journal, founded in 2009 by Springer, was accepted in January 2013 by Medline®, the U.S. National Library of Medicine's bibliographic database. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 23, 2013 Category: Global & Universal Source Type: news

Antibody Treatment For HIV
Data on SEEK's Novel Immunotherapy for HIV Published in Virology Journal SEEK, a privately-owned UK drug discovery group, announces that pre-clinical results on its HIV immunotherapy have been published in the peer-reviewed journal Virology Journal. SEEK's HIV immunotherapy triggers the immune system's cellular and antibody responses to selectively identify and kill HIV infected cells. The most exciting aspect of this therapy is that it directs the immune system towards short highly conserved regions of proteins produced by most circulating HIV strains... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 18, 2013 Category: Consumer Health News Tags: HIV / AIDS Source Type: news

New Resource: Jawetz, Melnick, & Adelberg’s Medical Microbiology, 26e Jawetz, Melnick, & Adelberg’s Medical Microbiology, 26e introduces you to basic clinical microbiology through the fields of bacteriology, virology, mycology, and parasitology.
(Source: AccessMedicine Updates)
Source: AccessMedicine Updates - April 14, 2013 Category: Internal Medicine Source Type: news

Study Finds Bird Virus Promising For Prostate Cancer Treatment
A study at the Virginia-Maryland Regional College of Veterinary Medicine has identified a chicken-killing virus as a promising treatment for prostate cancer in humans. Researchers have discovered that a genetically engineered Newcastle disease virus, which harms chickens but not humans, kills prostate cancer cells of all kinds, including hormone-resistant cancer cells. The work of Dr. Elankumaran Subbiah, associate professor of virology in the Department of Biomedical Sciences and Pathobiology, along with Dr... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 11, 2013 Category: Consumer Health News Tags: Prostate / Prostate Cancer Source Type: news

Rethinking The Mechanism Underlying The Well-Documented Efficacy Of Hepatitis A Vaccine
Viruses have historically been classified into one of two types - those with an outer lipid-containing envelope and those without an envelope. For the first time, researchers at the University of North Carolina have discovered that hepatitis A virus, a common cause of enterically-transmitted hepatitis, takes on characteristics of both virus types depending on whether it is in a host or in the environment. "The whole universe of virology is divided into two types of viruses - viruses that are enveloped and viruses that are not enveloped... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 8, 2013 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

Target Meeting's 2nd World Virology & Microbiology Online Conference Held On April 16-18, 2013: Join For Free
A Free Virtual Virology & Microbiology Conference at Targetmeeting.com featuring 60 live presentations (12 sessions) from academic and industry experts around the world. Computer and internet connection are required. Do not need any special equipment or software. All the attendees just connect to the online conference's server to participate in real time with their distinguished counterparts from across the globe. They can participate from their home or office depending on their convenience, which will save them the trouble of traveling and in utilizing their time optimally... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 3, 2013 Category: Consumer Health News Tags: Conferences Source Type: news

Newly Designed Vaccine Blocks H5 Avian Influenza In Animal Models
Until now most experimental vaccines against the highly lethal H5N1 avian influenza virus have lacked effectiveness. But a new vaccine has proven highly effective against the virus when tested in both mice and ferrets. It is also effective against the H9 subtype of avian influenza. The research is published online ahead of print in the Journal of Virology. The strength of the new vaccine is that it uses attenuated, rather than "killed" virus. (Killed viruses are broken apart with chemicals or heat, and they are used because they are safer than attenuated viruses... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 27, 2013 Category: Consumer Health News Tags: Bird Flu / Avian Flu Source Type: news

Cleverly designed vaccine blocks H5 avian influenza in models
(American Society for Microbiology) Until now, most experimental vaccines against the highly lethal H5N1 avian influenza virus have lacked effectiveness. But a new vaccine has proven highly effective against the virus when tested in both mice and ferrets. It is also effective against the H9 subtype of avian influenza. The research is published online ahead of print in the Journal of Virology. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 25, 2013 Category: Global & Universal Source Type: news

41 E-Books New on JEFFLINE
Scott Library added these 41 e-books in February and March to the growing collection: Age-related Macular Degeneration Bennett’s Cardiac Arrhythmias Breast Imaging Cell Physiology Sourcebook Chestnut’s Obstetric Anesthesia Choosing the Correct Radiologic Test Coté and Lerman’s a Practice of Anesthesia for Infants and Children Creative Solutions to Enhance Nursing Quality CT and MRI of the Whole Body Cytology: Diagnostic Principles and Clinical Correlates Drugs for the Heart Emergency Medicine: PreTest Self-Assessment and Review Emergency Ultrasound Exercise Prescription for Medical Conditions Fast...
Source: What's New on JEFFLINE - March 24, 2013 Category: Databases & Libraries Authors: Gary Kaplan Tags: All News Clinicians Researchers Students Teaching Faculty Source Type: news

Epstein-Barr Virus and AutoimmunityEpstein-Barr Virus and Autoimmunity
What is the role of Epstein-Barr Virus in the pathogenesis of MS and SLE? Future Virology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 15, 2013 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news

More Options for Treatment-Experienced HIV+ PatientsMore Options for Treatment-Experienced HIV+ Patients
Dr. Paul Sax reviews 3 presentations from CROI 2013 looking at new options for treatment-experienced patients with virologic failure. Medscape HIV/AIDS (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 14, 2013 Category: Consumer Health News Tags: HIV/AIDS Commentary Source Type: news

Community-based HIV-prevention efforts can boost testing, help reduce new infections
In Africa and Thailand, communities that worked together on HIV-prevention efforts saw not only a rise in HIV screening but a drop in new infections, according to a new study presented this week at the Conference on Retroviruses and Opportunistic Infections in Atlanta.   The U.S. National Institute of Mental Health's Project Accept — a trial conducted by the HIV Prevention Trials Network to test a combination of social, behavioral and structural HIV-prevention interventions — demonstrated that a series of community efforts was able to boost the number of people tested for...
Source: UCLA Newsroom: Health Sciences - March 5, 2013 Category: Universities & Medical Training Source Type: news

MSF Research Points to Ways to Expand Viral Load Testing for HIV in Developing Countries
Malawi 2011 © Nabila Kram An MSF staff member uses a SAMBA tool for rapid viral load monitoring. ATLANTA, MARCH 5, 2013—At the 20th Conference on Retroviruses and Opportunistic Infections (CROI) in Atlanta, the international medical humanitarian organization Doctors Without Borders/Médecins Sans Frontières (MSF) will present data today on strategies to reduce the costs and complexity of rolling out routine viral load monitoring in developing countries. Access to routine viral load monitoring will become increasingly important as WHO updates its HIV treatment guidelines and millions more peop...
Source: MSF News - March 5, 2013 Category: Global & Universal Source Type: news

HIV baby 'cured' through early treatment in US
Virologist Dr Deborah Persaud explains how a little girl from the US who was born with HIV has been cured after very early treatment. (Source: Telegraph Health)
Source: Telegraph Health - March 4, 2013 Category: Consumer Health News Tags: HIV baby cured Mississippi United States virologist doctors AIDS treatment baby with HIV cured infection drugs Source Type: news

H5N1 Infection Of Mammals Enabled By Mutation Altering Stability Of Surface Molecule In Acid
A single mutation in the H5N1 avian influenza virus that affects the pH at which the hemagglutinin surface protein is activated simultaneously reduces its capacity to infect ducks and enhances its capacity to grow in mice according to research published ahead of print in the Journal of Virology. "Knowing the factors and markers that govern the efficient growth of a virus in one host species, tissue, or cell culture versus another is of fundamental importance in viral infectious disease," says Charles J. Russell of St. Jude Children's Research Hospital, Memphis, TN, an author on the study... (Source: Health News f...
Source: Health News from Medical News Today - March 4, 2013 Category: Consumer Health News Tags: Bird Flu / Avian Flu Source Type: news

Merck scientist Daria Hazuda presents Bernard Fields Lecture at 20th Conference on Retroviruses and Opportunistic Infections (CROI)
(Cohn & Wolfe) Merck is announcing its worldwide head of Antiviral Basic Research and internationally renowned scientist, Daria Hazuda, Ph.D., presented the annual Bernard Fields Lecture at the opening session of the 20th Conference on Retroviruses and Opportunistic Infections (CROI 2013) in Atlanta. The annual lecture features a basic scientist who has made important and timely contributions to virology. Dr. Hazuda’s lecture, titled 'Antiretroviral Drug Discovery: HIV-1 Integrase Inhibitors and Beyond' will be available on the CROI website. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 4, 2013 Category: Global & Universal Source Type: news

Mutation altering stability of surface molecule in acid enables H5N1 infection of mammals
(American Society for Microbiology) A single mutation in the H5N1 avian influenza virus that affects the pH at which the hemagglutinin surface protein is activated simultaneously reduces its capacity to infect ducks and enhances its capacity to grow in mice according to research published ahead of print today in the Journal of Virology. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 28, 2013 Category: Global & Universal Source Type: news

Promising Viral Treatment For Prostate Cancer Without Unpleasant Side Effects
A recombinant Newcastle disease virus kills all kinds of prostate cancer cells, including hormone resistant cells, but leaves normal cells unscathed, according to a paper published online ahead of print in the Journal of Virology. A treatment for prostate cancer based on this virus would avoid the adverse side effects typically associated with hormonal treatment for prostate cancer, as well as those associated with cancer chemotherapies generally, says corresponding author Subbiah Elankumaran of Virginia Polytechnic Institute, Blacksburg... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 27, 2013 Category: Consumer Health News Tags: Prostate / Prostate Cancer Source Type: news

Molecular POC Diagnosis of Lower Respiratory InfectionsMolecular POC Diagnosis of Lower Respiratory Infections
Implementing molecular point-of-care testing for lower respiratory infections may enhance quality of care, but is it worth the cost? Future Virology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 27, 2013 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news

New Compounds Will Lead To A New Generation Of Anti-Influenza Drugs That The Virus' Strains Can't Adapt To
Simon Fraser University virologist Masahiro Niikura and his doctoral student Nicole Bance are among an international group of scientists that has discovered a new class of molecular compounds capable of killing the influenza virus. Working on the premise that too much of a good thing can be a killer, the scientists have advanced previous researchers' methods of manipulating an enzyme that is key to how influenza replicates and spreads... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 25, 2013 Category: Consumer Health News Tags: Flu / Cold / SARS Source Type: news

Virus shows promise as prostate cancer treatment
(American Society for Microbiology) A recombinant Newcastle disease virus kills all kinds of prostate cancer cells, including hormone resistant cells, but leaves normal cells unscathed, according to a paper published online ahead of print in the Journal of Virology. A treatment for prostate cancer based on this virus would avoid the adverse side effects typically associated with hormonal treatment for prostate cancer, as well as those associated with cancer chemotherapies generally. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 25, 2013 Category: Global & Universal Source Type: news

RCT: nevirapine vs. efavirenz for patients co-infected with HIV and tuberculosis
Source: Lancet Infectious Diseases Area: News Nevirapine and efavirenz are widely used as antiretroviral therapy in countries with high incidence of HIV and tuberculosis co-infection but both drugs interact with antituberculosis drugs. The authors of a study, published online in Lancet Infectious Diseases, compared the efficacy and safety of a nevirapine-based antiretroviral therapy (started at full dose) with an efavirenz-based regimen in co-infected patients receiving antituberculosis medication.   The study was a multicentre, open-label, non-inferiority trial conducted at three health centres in Mozambique. Pa...
Source: NeLM - News - February 22, 2013 Category: Drugs & Pharmacology Source Type: news

Influenza study: Meet virus' new enemy
(Simon Fraser University) Simon Fraser University virologist Masahiro Niikura and his doctoral student Nicole Bance are among an international group of scientists that has discovered a new class of molecular compounds capable of killing the influenza virus. Working on the premise that too much of a good thing can be a killer, the scientists have advanced previous researchers' methods of manipulating an enzyme that is key to how influenza replicates and spreads. Science Express has published the work. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 21, 2013 Category: Global & Universal Source Type: news

Horizon scanning: Phase III (FUSION) results for sofosbuvir in chronic hepatitis C
Source: BioSpace Area: News Gilead Sciences has announced topline results from the phase III FUSION study evaluating sofosbuvir plus ribavirin (RBV) in treatment-experienced patients with genotype 2 or 3 chronic hepatitis C virus (HCV) infection who failed prior interferon-based treatment.   In the FUSION study, patients were randomised to either a 12-week (n=103) or 16-week (n=98) course of sofosbuvir 400 mg once daily plus RBV (1,000 or 1,200 mg/day). The primary efficacy endpoint was superiority compared to a predefined historic control sustained virological response (SVR) rate of 25%.   The followin...
Source: NeLM - News - February 20, 2013 Category: Drugs & Pharmacology Source Type: news

Virology researcher awarded nearly $2 million to study chronic hepatitis E
(Virginia Tech) A Virginia-Maryland Regional College of Veterinary Medicine scientist has been awarded nearly $2 million from the National Institutes of Health to better understand chronic hepatitis E virus by focusing on patients with chronic infections. The project seeks to develop a chronic hepatitis E model to study how and why the disease progresses into chronicity and its possible medical prevention and treatment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 19, 2013 Category: Global & Universal Source Type: news

Hepatitis C drug has two modes of action
CHICAGO, Feb. 18 (UPI) -- U.S. and French mathematical modelers, clinicians and molecular virologists say the anti-viral daclatasvir has two modes of action against hepatitis C virus. (Source: Health News - UPI.com)
Source: Health News - UPI.com - February 19, 2013 Category: Consumer Health News Source Type: news

Published Work On Respiratory Syncytial Virus In Children From Le Bonheur Children's Hospital
Studies at Le Bonheur are advancing our understanding of how viruses, including RSV, replicate in humans, mutate to avoid the immune response and can be effectively treated. John DeVincenzo, MD, medical director of Molecular Diagnostics and Virology Laboratories at Le Bonheur, and professor of Pediatrics and Microbiology, Immunology, and Molecular Biology at The University of Tennessee Health Science Center, has recently published three papers on this topic. DeVincenzo's lab is one of only two of its kind in the United States... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 18, 2013 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

New study on Hepatitis C drug treatment in vivo and in vitro
(Loyola University Health System) An interdisciplinary effort by mathematical modelers, clinicians and virologists has revealed that daclatasvir has two main modes of action against HCV and also yields a more accurate new estimate of the HCV half-life. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - February 18, 2013 Category: Global & Universal Source Type: news

Microbes team up to boost plants' stress tolerance
(Penn State) While most farmers consider viruses and fungi potential threats to their crops, these microbes can help wild plants adapt to extreme conditions, according to a Penn State virologist. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - February 17, 2013 Category: Biology Source Type: news

Development of SARS Vaccines and Therapeutics Still NeededDevelopment of SARS Vaccines and Therapeutics Still Needed
The development of vaccines and therapeutics for the prevention and treatment of SARS is still an urgent issue that needs to be addressed. Future Virology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 13, 2013 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news

Seed-borne plant virus diseases(Sastry)
(Source: Springer Biomedical Sciences titles)
Source: Springer Biomedical Sciences titles - February 12, 2013 Category: Biomedical Science Tags: Virology Source Type: news

Newly identified natural protein blocks HIV, other deadly viruses
A team of UCLA-led researchers has identified a protein with broad virus-fighting properties that potentially could be used as a weapon against deadly human pathogenic viruses such as HIV, Ebola, Rift Valley Fever, Nipah and others designated "priority pathogens" for national biosecurity purposes by the National Institute of Allergy and Infectious Disease.   In a study published in the January issue of the journal Immunity, the researchers describe the novel antiviral property of the protein, cholesterol-25-hydroxylase (CH25H), an enzyme that converts cholesterol to an oxysterol called 25-hydroxycholesterol ...
Source: UCLA Newsroom: Health Sciences - February 11, 2013 Category: Universities & Medical Training Source Type: news

Social media may prove useful in prevention of HIV, STDs, study shows
This study helps direct us toward that goal by suggesting that participants will use social media to learn about HIV prevention and that those who talk about HIV prevention over social networking groups are not just talking about it — they are acting on their words by getting an HIV test."   The study also demonstrates that social networking can be a useful tool for collecting and analyzing data, added Young, who is a member of the Center for HIV Identification, Prevention and Treatment Services (CHIPTS) at UCLA.   "Having one platform that allows multiple types of data collection and an...
Source: UCLA Newsroom: Health Sciences - February 6, 2013 Category: Universities & Medical Training Source Type: news

Horizon scanning: Phase III results for sofosbuvir in chronic hepatitis C
Source: BioSpace Area: News BioSpace has reported on the results of two Phase III studies of the investigative antiviral sofosbuvir in combination with ribavirin (FISSION) and in combination with ribavirin and pegylated interferon (NEUTRINO) in the first-line treatment of patients with chronic hepatitis C virus (HCV) infection.   In the FISSION study, treatment-naïve patients with HCV genotype 2 or 3 were randomised to receive either 12 weeks of sofosbuvir (400mg once daily) plus ribavirin (1,000 or 1,200 mg/day) (n=256) or standard of care with 24 weeks of pegylated interferon alfa-2a (peg-IFN; 180 mcg/wee...
Source: NeLM - News - February 5, 2013 Category: Drugs & Pharmacology Source Type: news

Switch From Epzicom to Truvada Maintains HIV Suppression: StudySwitch From Epzicom to Truvada Maintains HIV Suppression: Study
Virologic suppression was maintained when HIV patients switched from lamivudine/abacavir (ABC/3TC) to emtricitibine/tenofovir (FTC/TDF) in the pharma-funded SWIFT study. Reuters Health Information (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - February 4, 2013 Category: Infectious Diseases Tags: HIV/AIDS News Source Type: news

U.S. virologists intentionally engineer super-deadly pandemic flu virus
Two American researchers whose efforts to deliberately re-engineer the H5N1 avian flu virus to be more virulent and deadly to humans are now asking that a government-advised moratorium on their controversial research be lifted. According to TIME, the duo alleges that... (Source: NaturalNews.com)
Source: NaturalNews.com - January 31, 2013 Category: Consumer Health News Source Type: news

Disclosure of Maternal HIV Status to ChildrenDisclosure of Maternal HIV Status to Children
When and how should HIV infected mothers disclose their HIV-status to their non-infected children? Future Virology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 30, 2013 Category: Consumer Health News Tags: HIV/AIDS Journal Article Source Type: news

Low Vitamin D Levels and HIV-Hepatitis C TherapyLow Vitamin D Levels and HIV-Hepatitis C Therapy
Low vitamin D levels may impair virologic response to PEGIFN + RBV therapy in HIV-hepatitis C patients. AIDS (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 28, 2013 Category: Consumer Health News Tags: HIV/AIDS Journal Article Source Type: news

Man flu: an enigma wrapped in a damp towel | Stuart Jeffries
I'm not sure that research focusing on the preoptic nucleus will settle things – it's really a matter for the psychology of illnessIt's a truth universally acknowledged that men are pathetic. Around this time of year, the man in your life will get the merest sniffle and retire to bed until the middle of next month. He'll take all the toilet rolls, the box set of Game of Thrones and a punchably pitiful look that says, like some Vietnam vet, "You weren't there, man. You wouldn't understand." He'll also take his mobile phone, for reasons that will become clear in a moment.Meanwhile, you will continue heroicall...
Source: Guardian Unlimited Science - January 25, 2013 Category: Science Authors: Stuart Jeffries Tags: Comment Infectious diseases Health guardian.co.uk Medical research Microbiology Society Flu Gender Science Comment is free Source Type: news

Man flu: an enigma wrapped in a damp towel
I'm not sure that research focusing on the preoptic nucleus will settle things – it's really a matter for the psychology of illnessIt's a truth universally acknowledged that men are pathetic. Around this time of year, the man in your life will get the merest sniffle and retire to bed until the middle of next month. He'll take all the toilet rolls, the box set of Game of Thrones and a punchably pitiful look that says, like some Vietnam vet, "You weren't there, man. You wouldn't understand." He'll also take his mobile phone, for reasons that will become clear in a moment.Meanwhile, you will continue heroicall...
Source: Guardian Unlimited Science - January 25, 2013 Category: Science Authors: Stuart Jeffries Tags: Comment Infectious diseases Health guardian.co.uk Medical research Microbiology Society Flu Gender Science Comment is free Source Type: news

IL28B Polymorphisms and Response to Therapy in Chronic HCVIL28B Polymorphisms and Response to Therapy in Chronic HCV
Which biomarkers could potentially help clinicians predict virological responses in patients with chronic hepatitis C? Journal of Viral Hepatitis (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 25, 2013 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Bird flu researchers get green light to continue work on engineered virus
A voluntary moratorium on research involving lab-created versions of the H5N1 bird flu virus has been liftedResearch on lab-engineered strains of the H5N1 bird flu virus is set to restart a year after the scientists voluntarily paused it to allow for an international public debate on the safest way to proceed.Last year, two teams of scientists in the United States and the Netherlands submitted papers for publication in Science and Nature describing how they had engineered the H5N1 bird flu virus – which kills half of the people it infects but cannot naturally transmit from person to person – to spread more easi...
Source: Guardian Unlimited Science - January 23, 2013 Category: Science Authors: Alok Jha Tags: Bird flu Genetics Biology World news Infectious diseases Health guardian.co.uk Medical research Microbiology Society Controversies in science Source Type: news

Systematic review and meta-analysis of clinical use of HIV integrase inhibitors
Source: PLoS One Area: News Integrase inhibitors have swiftly been adopted as part of current antiretroviral regimens. This systematic review and meta-analysis was carried of current evidence regarding the use of these agents in various clinical settings.   A search was conducted of the literature from April 2006 until November 2012, for RCTs and non-RCTs, and cohort studies. A total of 48 unique studies (including 15 abstract-only reports) were included on the use of integrase inhibitors in antiretroviral therapy-naive patients and treatment-experienced patients with either virological failure or switching to in...
Source: NeLM - News - January 17, 2013 Category: Drugs & Pharmacology Source Type: news

Economic savings versus health losses: The cost-effectiveness of generic antiretroviral therapy in the United States
Source: Ann Intern Med Area: News The Annals of Internal Medicine has featured a cost-effectiveness analysis of a 3-pill, generic-based antiretroviral regimen compared with a branded, co-formulated regimen.   U.S. HIV treatment guidelines recommend branded once-daily, 1-pill efavirenz-emtricitabine-tenofovir as first-line antiretroviral therapy (ART). With the anticipated approval of generic efavirenz in the United States, a once-daily, 3-pill alternative (generic efavirenz, generic lamivudine, and tenofovir) will decrease cost but may reduce adherence and virological suppression.   The analysis was base...
Source: NeLM - News - January 16, 2013 Category: Drugs & Pharmacology Source Type: news

Immunological Nonresponse to ART Drugs in HIV InfectionImmunological Nonresponse to ART Drugs in HIV Infection
What is the best approach to treating the immunological nonresponse to ARV drugs in HIV infection? Future Virology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 16, 2013 Category: Consumer Health News Tags: HIV/AIDS Journal Article Source Type: news

Systematic review: Effectiveness of antiviral treatment for hepatitis C virus infection in adults
Source: Ann Intern Med Area: News This systematic review compared the safety and efficacy of various antiviral treatments for chronic hepatitis C virus (HCV) infection in treatment-naive adults. The researchers searched Medline, Cochrane, Embase, Scopus, PsychINFO, and clinical trial registries for English-language randomised controlled trials of antiviral treatments and cohort studies examining associations between sustained virological response (SVR) after therapy and clinical outcomes.   The following findings were noted:   . No trial was identified that evaluated effectiveness of treatment on lo...
Source: NeLM - News - January 15, 2013 Category: Drugs & Pharmacology Source Type: news