Log in to search using one of your social media accounts:

 

In Mouse Models, New Agent Inhibits HCV Replication
Treatments against hepatitis C virus have only been partially successful. A major problem is that antivirals generate drug resistance. Now Seong-Wook Lee of Dankook University, Yongin, Republic of Korea and his collaborators have developed agents that bind to the business end of a critical protein, disabling it so successfully that no resistance has arisen. The research is published in the June 2013 issue of the Journal of Virology. The target protein for the new agents is the NS5B replicase protein, which is the central catalytic enzyme in HCV replication... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 3, 2013 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

Protection Against Post-Influenza Bacterial Superinfection Offered By Interleukin-22
Researchers from the Pasteur Institute, Lille, France have shown in a mouse model that interleukin-22 protects against bacterial superinfections that can arise following influenza. Their research is published in the June 2013 issue of the Journal of Virology. Influenza A viral infection can lead to primary pneumonia and, later on, to serious complications including secondary bacterial pneumonia and sepsis. Post-influenza bacterial superinfections that occur during seasonal epidemics and pandemics are of great concern to human health and impose a considerable socio-economic burden... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 3, 2013 Category: Consumer Health News Tags: Flu / Cold / SARS Source Type: news

No Benefit Of Double Dose Antiviral Drug For Severe Influenza
Findings have major implications for stockpiling drugs during pandemics, say experts There are no virological or clinical benefits of giving double doses of the antiviral drug oseltamivir (Tamiflu) to patients admitted to hospital with severe influenza, finds a large study from South East Asia published on bmj.com today. This is the first study to examine the effectiveness of higher doses of oseltamivir in cases of hospitalized severe human influenza (seasonal, pandemic and bird flu strains)... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 31, 2013 Category: Consumer Health News Tags: Flu / Cold / SARS Source Type: news

New agent inhibits HCV replication in mouse models -- No resistance seen
(American Society for Microbiology) Treatments against hepatitis C virus have only been partially successful. A major problem is that antivirals generate drug resistance. Now Seong-Wook Lee of Dankook University, Yongin, Republic of Korea and his collaborators have developed agents that bind to the business end of a critical protein, disabling it so successfully that no resistance has arisen. The research is published in the June 2013 issue of the Journal of Virology. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 30, 2013 Category: Global & Universal Source Type: news

Interleukin-22 protects against post-influenza bacterial superinfection
(American Society for Microbiology) Researchers from the Pasteur Institute, Lille, France have shown in a mouse model that interleukin-22 protects against bacterial superinfections that can arise following influenza. Their research is published in the June 2013 issue of the Journal of Virology. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 30, 2013 Category: Global & Universal Source Type: news

Double dose of antiviral drug offers no added benefit in severe influenza
(Wellcome Trust) Giving double doses of the antiviral drug oseltamivir, or Tamiflu, offers no clinical or virological advantages over a standard dose for patients admitted to hospital with severe influenza infection, according to a randomized trial published today and funded by the Wellcome Trust, US National Institute of Allergy and Infectious Diseases and the Singapore National Medical Research Council. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - May 30, 2013 Category: Infectious Diseases Source Type: news

Drug Resistance To Tamiflu Confirmed For H7N9 Virus
Resistance to treatment with Tamiflu (oseltamivir) and similar drugs in people who have the H7N9 flu virus has now been confirmed, according to new research published in The Lancet. Described as one of the most detailed virological studies of the H7N9 virus to date, the study was led by Dr Zhenghong Yuang of the Shanghai Public Health Clinical Centre and School of Basic Medical Sciences, Shanghai Medical College of Fudan University, China, and Dr Malik Peiris, of the University of Hong Kong, China... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 29, 2013 Category: Consumer Health News Tags: Flu / Cold / SARS Source Type: news

IL-21 Signals Important For Antibody-Producing Cells And T Helper Cells That Support Them
Scientists at Emory Vaccine Center have shown that an immune regulatory molecule called IL-21 is needed for long-lasting antibody responses in mice against viral infections. The results are published in the Journal of Virology. "Our findings highlight how IL-21 could be important in the development of antiviral vaccines," says research associate Ata Ur Rasheed Mohammed, PhD, the first author of the paper. The senior author is Rafi Ahmed, PhD, director of the Emory Vaccine Center and a Georgia Research Alliance Eminent Scholar... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 28, 2013 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Computer Model Predicts When Viruses Become Infectious
A new computer model could help scientists predict when a particular strain of avian influenza might become infectious from bird to human, according to a report to be published in the International Journal Data Mining and Bioinformatics. Chuang Ma of the University of Arizona, Tucson, and colleagues at the Huazhong University of Science and Technology, Wuhan and the Wuhan Institute of Virology, explain that since 1997 several strains of avian influenza A virus (AIV), commonly known as "bird flu" have infected people directly from their natural bird hosts leading to numerous deaths... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 23, 2013 Category: Consumer Health News Tags: Bird Flu / Avian Flu Source Type: news

Adverse Events Common With Triple Therapy in HCV CirrhosisAdverse Events Common With Triple Therapy in HCV Cirrhosis
In cirrhotic patients, triple-therapy against hepatitis C virus (HCV) produces a high virological response rate, but at the cost of a high rate of serious adverse events, French researchers say. Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 22, 2013 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Evidence of host adaptation of avian-origin influenza A virus
This study will be published on Science China Life Sciences 2013, No.6. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 15, 2013 Category: Global & Universal Source Type: news

Robert Webster, Ph.D., presented with National Foundation for Infectious Diseases award
Virologist Robert G. Webster, Ph.D., of St. Jude Children’s Research Hospital, is the recipient of the Charles Mérieux Award from the National Foundation for Infectious Diseases (NFID). (Source: St. Jude Children's Research Hospital)
Source: St. Jude Children's Research Hospital - May 14, 2013 Category: Pediatrics Source Type: news

Mosquito Survey Identifies Reservoir Of Disease
A large scale, five year study of mosquitoes from different ecological regions in Kenya, including savannah grassland, semi-arid Acacia thorn bushes, and mangrove swamps, found a reservoir of viruses carried by mosquitoes (arboviruses) that are responsible for human and animal diseases. This research, published in BioMed Central's open access journal Virology Journal, highlights the need for continued surveillance in order to monitor the risk of disease outbreaks... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 10, 2013 Category: Consumer Health News Tags: Tropical Diseases Source Type: news

Faldaprevir Early Hepatitis C Treatment Success, Viral CureFaldaprevir Early Hepatitis C Treatment Success, Viral Cure
The protease inhibitor combined with interferon and ribavirin achieved virologic cure in up to 80% of patients. Many were able to stop all treatment at 24 weeks. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 8, 2013 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Tamil Nadu to set up Virology labs
Tamil Nadu government would soon set up Molecular Virology Laboratories in Medical College Hospitals in Chennai, Madurai, Coimbatore and Tirunelveli. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - May 8, 2013 Category: Pharmaceuticals Source Type: news

Poultry trade 'may be spreading bird flu'
Poultry workers moving to and from wet markets and farms may be responsible for the spread of the deadly H7N9 virus in China, says a virologist who's working with the World Health Organization to investigate the outbreak. (Source: WDSU.com - Health)
Source: WDSU.com - Health - May 6, 2013 Category: Consumer Health News Source Type: news

New bird flu strain requires vigilance researchers warn
Conclusion This is important research tracking the origins of the new H7N9 bird flu virus, which gives some clues about how it might behave in the future. Scientists are particularly concerned that a future mutation could mean it is transmitted between humans, which increases the risk of a pandemic (an epidemic of infection across countries or continents). For travellers to China and other countries affected by bird flu, it's important to observe the following precautions: avoid visiting live animal markets and poultry farms avoid contact with surfaces that are contaminated with animal faeces don't eat or handle u...
Source: NHS News Feed - May 2, 2013 Category: Consumer Health News Tags: Genetics/stem cells Medical practice Source Type: news

Nigeria: Tomori Tasks President Jonathan On Polio Eradication
[Vanguard]As Nigeria battles rejection of polio vaccination in the North, renowned Virologist, Professor Oyewale Tomori has alleged that Nigerian leaders are yet to show enough commitment needed to attain the global eradication deadline by 2018. (Source: AllAfrica News: Polio)
Source: AllAfrica News: Polio - April 30, 2013 Category: Infectious Diseases Source Type: news

Antiretroviral regimen associated with less virological failure among HIV-infected children
(The JAMA Network Journals) Elizabeth D. Lowenthal, M.D., M.S.C.E., of the University of Pennsylvania Perelman School of Medicine and Children's Hospital of Philadelphia, and colleagues conducted a study to determine whether there was a difference in time to virological failure between HIV-infected children initiating nevirapine vs. efavirenz-based antiretroviral treatment in Botswana. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 30, 2013 Category: Global & Universal Source Type: news

Influenza Pandemics of 1918 and 2009Influenza Pandemics of 1918 and 2009
Studying the similar features of the 1918 and 2009 influenza pandemics may provide better control of influenza pandemics in the future. Future Virology (Source: Medscape PublicHealth Headlines)
Source: Medscape PublicHealth Headlines - April 29, 2013 Category: Primary Care Tags: Infectious Diseases Journal Article Source Type: news

Oral Regimen Sustains Hepatitis C Viral Response to 24 WeeksOral Regimen Sustains Hepatitis C Viral Response to 24 Weeks
A regimen of 3 oral direct-acting antiviral drugs plus ribavirin produced sustained virologic responses above 90% in a broad range of patients infected with hepatitis C. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 25, 2013 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Simeprevir Administered Once Daily Demonstrates Sustained Virologic Response In Genotype 1 Chronic Hepatitis C Patients, Studies Find
Janssen R&D Ireland (Janssen) have announced primary efficacy and safety results from two global Phase 3 studies demonstrating that use of the investigational protease inhibitor simeprevir (TMC435) led to sustained virologic response 12 weeks after the end of treatment (SVR12) in 80 and 81 percent, respectively, of treatment-naïve genotype 1 chronic hepatitis C adult patients with compensated liver disease, including all stages of liver fibrosis, when administered once daily with pegylated interferon and ribavirin... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 25, 2013 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

Vesicular Stomatitis Virus Kills Melanoma In Animal Model, Spares Normal Cells
Researchers from Yale University School of Medicine have demonstrated that vesicular stomatitis virus (VSV) is highly competent at finding, infecting, and killing human melanoma cells, both in vitro and in animal models, while having little propensity to infect non-cancerous cells. "If it works as well in humans, this could confer a substantial benefit on patients afflicted with this deadly disease," says Anthony van den Pol, a researcher on the study. The research was published online ahead of print in the Journal of Virology... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 25, 2013 Category: Consumer Health News Tags: Melanoma / Skin Cancer Source Type: news

Food and Environmental Virology adds society affiliation
(Springer) Springer's journal Food and Environmental Virology is now the official publication of the International Society for Food and Environmental Virology. The new affiliation takes effect immediately. The journal, founded in 2009 by Springer, was accepted in January 2013 by Medline®, the U.S. National Library of Medicine's bibliographic database. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 23, 2013 Category: Global & Universal Source Type: news

Antibody Treatment For HIV
Data on SEEK's Novel Immunotherapy for HIV Published in Virology Journal SEEK, a privately-owned UK drug discovery group, announces that pre-clinical results on its HIV immunotherapy have been published in the peer-reviewed journal Virology Journal. SEEK's HIV immunotherapy triggers the immune system's cellular and antibody responses to selectively identify and kill HIV infected cells. The most exciting aspect of this therapy is that it directs the immune system towards short highly conserved regions of proteins produced by most circulating HIV strains... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 18, 2013 Category: Consumer Health News Tags: HIV / AIDS Source Type: news

New Resource: Jawetz, Melnick, & Adelberg’s Medical Microbiology, 26e Jawetz, Melnick, & Adelberg’s Medical Microbiology, 26e introduces you to basic clinical microbiology through the fields of bacteriology, virology, mycology, and parasitology.
(Source: AccessMedicine Updates)
Source: AccessMedicine Updates - April 14, 2013 Category: Internal Medicine Source Type: news

Study Finds Bird Virus Promising For Prostate Cancer Treatment
A study at the Virginia-Maryland Regional College of Veterinary Medicine has identified a chicken-killing virus as a promising treatment for prostate cancer in humans. Researchers have discovered that a genetically engineered Newcastle disease virus, which harms chickens but not humans, kills prostate cancer cells of all kinds, including hormone-resistant cancer cells. The work of Dr. Elankumaran Subbiah, associate professor of virology in the Department of Biomedical Sciences and Pathobiology, along with Dr... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 11, 2013 Category: Consumer Health News Tags: Prostate / Prostate Cancer Source Type: news

Rethinking The Mechanism Underlying The Well-Documented Efficacy Of Hepatitis A Vaccine
Viruses have historically been classified into one of two types - those with an outer lipid-containing envelope and those without an envelope. For the first time, researchers at the University of North Carolina have discovered that hepatitis A virus, a common cause of enterically-transmitted hepatitis, takes on characteristics of both virus types depending on whether it is in a host or in the environment. "The whole universe of virology is divided into two types of viruses - viruses that are enveloped and viruses that are not enveloped... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 8, 2013 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

Target Meeting's 2nd World Virology & Microbiology Online Conference Held On April 16-18, 2013: Join For Free
A Free Virtual Virology & Microbiology Conference at Targetmeeting.com featuring 60 live presentations (12 sessions) from academic and industry experts around the world. Computer and internet connection are required. Do not need any special equipment or software. All the attendees just connect to the online conference's server to participate in real time with their distinguished counterparts from across the globe. They can participate from their home or office depending on their convenience, which will save them the trouble of traveling and in utilizing their time optimally... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 3, 2013 Category: Consumer Health News Tags: Conferences Source Type: news

Newly Designed Vaccine Blocks H5 Avian Influenza In Animal Models
Until now most experimental vaccines against the highly lethal H5N1 avian influenza virus have lacked effectiveness. But a new vaccine has proven highly effective against the virus when tested in both mice and ferrets. It is also effective against the H9 subtype of avian influenza. The research is published online ahead of print in the Journal of Virology. The strength of the new vaccine is that it uses attenuated, rather than "killed" virus. (Killed viruses are broken apart with chemicals or heat, and they are used because they are safer than attenuated viruses... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 27, 2013 Category: Consumer Health News Tags: Bird Flu / Avian Flu Source Type: news

Cleverly designed vaccine blocks H5 avian influenza in models
(American Society for Microbiology) Until now, most experimental vaccines against the highly lethal H5N1 avian influenza virus have lacked effectiveness. But a new vaccine has proven highly effective against the virus when tested in both mice and ferrets. It is also effective against the H9 subtype of avian influenza. The research is published online ahead of print in the Journal of Virology. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 25, 2013 Category: Global & Universal Source Type: news

41 E-Books New on JEFFLINE
Scott Library added these 41 e-books in February and March to the growing collection: Age-related Macular Degeneration Bennett’s Cardiac Arrhythmias Breast Imaging Cell Physiology Sourcebook Chestnut’s Obstetric Anesthesia Choosing the Correct Radiologic Test Coté and Lerman’s a Practice of Anesthesia for Infants and Children Creative Solutions to Enhance Nursing Quality CT and MRI of the Whole Body Cytology: Diagnostic Principles and Clinical Correlates Drugs for the Heart Emergency Medicine: PreTest Self-Assessment and Review Emergency Ultrasound Exercise Prescription for Medical Conditions Fast...
Source: What's New on JEFFLINE - March 24, 2013 Category: Databases & Libraries Authors: Gary Kaplan Tags: All News Clinicians Researchers Students Teaching Faculty Source Type: news

Epstein-Barr Virus and AutoimmunityEpstein-Barr Virus and Autoimmunity
What is the role of Epstein-Barr Virus in the pathogenesis of MS and SLE? Future Virology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 15, 2013 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news

More Options for Treatment-Experienced HIV+ PatientsMore Options for Treatment-Experienced HIV+ Patients
Dr. Paul Sax reviews 3 presentations from CROI 2013 looking at new options for treatment-experienced patients with virologic failure. Medscape HIV/AIDS (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 14, 2013 Category: Consumer Health News Tags: HIV/AIDS Commentary Source Type: news

Community-based HIV-prevention efforts can boost testing, help reduce new infections
In Africa and Thailand, communities that worked together on HIV-prevention efforts saw not only a rise in HIV screening but a drop in new infections, according to a new study presented this week at the Conference on Retroviruses and Opportunistic Infections in Atlanta.   The U.S. National Institute of Mental Health's Project Accept — a trial conducted by the HIV Prevention Trials Network to test a combination of social, behavioral and structural HIV-prevention interventions — demonstrated that a series of community efforts was able to boost the number of people tested for...
Source: UCLA Newsroom: Health Sciences - March 5, 2013 Category: Universities & Medical Training Source Type: news

MSF Research Points to Ways to Expand Viral Load Testing for HIV in Developing Countries
Malawi 2011 © Nabila Kram An MSF staff member uses a SAMBA tool for rapid viral load monitoring. ATLANTA, MARCH 5, 2013—At the 20th Conference on Retroviruses and Opportunistic Infections (CROI) in Atlanta, the international medical humanitarian organization Doctors Without Borders/Médecins Sans Frontières (MSF) will present data today on strategies to reduce the costs and complexity of rolling out routine viral load monitoring in developing countries. Access to routine viral load monitoring will become increasingly important as WHO updates its HIV treatment guidelines and millions more peop...
Source: MSF News - March 5, 2013 Category: Global & Universal Source Type: news

HIV baby 'cured' through early treatment in US
Virologist Dr Deborah Persaud explains how a little girl from the US who was born with HIV has been cured after very early treatment. (Source: Telegraph Health)
Source: Telegraph Health - March 4, 2013 Category: Consumer Health News Tags: HIV baby cured Mississippi United States virologist doctors AIDS treatment baby with HIV cured infection drugs Source Type: news

H5N1 Infection Of Mammals Enabled By Mutation Altering Stability Of Surface Molecule In Acid
A single mutation in the H5N1 avian influenza virus that affects the pH at which the hemagglutinin surface protein is activated simultaneously reduces its capacity to infect ducks and enhances its capacity to grow in mice according to research published ahead of print in the Journal of Virology. "Knowing the factors and markers that govern the efficient growth of a virus in one host species, tissue, or cell culture versus another is of fundamental importance in viral infectious disease," says Charles J. Russell of St. Jude Children's Research Hospital, Memphis, TN, an author on the study... (Source: Health News f...
Source: Health News from Medical News Today - March 4, 2013 Category: Consumer Health News Tags: Bird Flu / Avian Flu Source Type: news

Merck scientist Daria Hazuda presents Bernard Fields Lecture at 20th Conference on Retroviruses and Opportunistic Infections (CROI)
(Cohn & Wolfe) Merck is announcing its worldwide head of Antiviral Basic Research and internationally renowned scientist, Daria Hazuda, Ph.D., presented the annual Bernard Fields Lecture at the opening session of the 20th Conference on Retroviruses and Opportunistic Infections (CROI 2013) in Atlanta. The annual lecture features a basic scientist who has made important and timely contributions to virology. Dr. Hazuda’s lecture, titled 'Antiretroviral Drug Discovery: HIV-1 Integrase Inhibitors and Beyond' will be available on the CROI website. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 4, 2013 Category: Global & Universal Source Type: news

Mutation altering stability of surface molecule in acid enables H5N1 infection of mammals
(American Society for Microbiology) A single mutation in the H5N1 avian influenza virus that affects the pH at which the hemagglutinin surface protein is activated simultaneously reduces its capacity to infect ducks and enhances its capacity to grow in mice according to research published ahead of print today in the Journal of Virology. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 28, 2013 Category: Global & Universal Source Type: news

Promising Viral Treatment For Prostate Cancer Without Unpleasant Side Effects
A recombinant Newcastle disease virus kills all kinds of prostate cancer cells, including hormone resistant cells, but leaves normal cells unscathed, according to a paper published online ahead of print in the Journal of Virology. A treatment for prostate cancer based on this virus would avoid the adverse side effects typically associated with hormonal treatment for prostate cancer, as well as those associated with cancer chemotherapies generally, says corresponding author Subbiah Elankumaran of Virginia Polytechnic Institute, Blacksburg... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 27, 2013 Category: Consumer Health News Tags: Prostate / Prostate Cancer Source Type: news

Molecular POC Diagnosis of Lower Respiratory InfectionsMolecular POC Diagnosis of Lower Respiratory Infections
Implementing molecular point-of-care testing for lower respiratory infections may enhance quality of care, but is it worth the cost? Future Virology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 27, 2013 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news