COVID-19: Epidemiology, virology, and prevention, UpToDate (Updated 16th February 2023)
Coronaviruses are important human and animal pathogens. At the end of 2019, a novel coronavirus was identified as the cause of a cluster of pneumonia cases in Wuhan, a city in the Hubei Province of China. It rapidly spread, resulting in an epidemic throughout China, followed by a global pandemic. In February 2020, the World Health Organization designated the disease COVID-19, which stands for coronavirus disease 2019 [ 2 External 0 0 0 1 false https://www.uptodate.com/contents/covid-19-epidemiology-virology-and-prevention/abstract/1 true false%>]. The virus that causes COVID-19 is designated severe acute respiratory syndr...
Source: Current Awareness Service for Health (CASH) - March 2, 2023 Category: Consumer Health News Source Type: news

What We Know About the U.S. Intelligence Community ’ s Split on COVID-19 Origins
News that the U.S. Department of Energy made a determination about the origins of COVID-19 has sparked new questions about the U.S. intelligence community’s investigation of the global pandemic that has killed an estimated 6.85 million people. The Energy Department, which runs multiple national laboratories, concluded with a low level of confidence that COVID-19 most likely emerged as a result of a leak from a laboratory in China, the Wall Street Journal reported on Sunday, citing anonymous sources. The Journal reported that the Energy Department’s new determination was classified. Previously, the agency was un...
Source: TIME: Health - February 28, 2023 Category: Consumer Health News Authors: Mini Racker Tags: Uncategorized COVID-19 Explainer National Security Source Type: news

Former commander of Britain's chemical and biological regiment demands action over Covid lab leak
A growing number of experts now believe coronavirus leaked from the Wuhan Institute of Virology, having previously said they were 'undecided'. (Source: the Mail online | Health)
Source: the Mail online | Health - February 28, 2023 Category: Consumer Health News Source Type: news

What We Know About the Lab Leak Theory and the Origins of Covid
Scientists and spy agencies have tried to determine where the coronavirus originated, but conclusive evidence is hard to come by and the nation ’s intelligence agencies are split. (Source: NYT Health)
Source: NYT Health - February 28, 2023 Category: Consumer Health News Authors: Sheryl Gay Stolberg and Benjamin Mueller Tags: Coronavirus (2019-nCoV) China Wuhan (China) Wuhan Institute of Virology (China) Espionage and Intelligence Services Laboratories and Scientific Equipment Research Animals Wildlife Trade and Poaching Classified Information and State Secre Source Type: news

Where Did Covid Originate? Here ’s What We Know and Don’t Know
Scientists and spy agencies have tried to determine where the coronavirus originated, but conclusive evidence is hard to come by and the nation ’s intelligence agencies are split. (Source: NYT Health)
Source: NYT Health - February 28, 2023 Category: Consumer Health News Authors: Sheryl Gay Stolberg and Benjamin Mueller Tags: Coronavirus (2019-nCoV) China Wuhan (China) Wuhan Institute of Virology (China) Espionage and Intelligence Services Laboratories and Scientific Equipment Research Animals Wildlife Trade and Poaching Classified Information and State Secre Source Type: news

The Scientific Error That Might Have Caused The Covid-19 Pandemic
We still don ’t know where Covid-19 started, although evidence is growing that it started in a lab in Wuhan that was doing gain-of-function research. Why do some virologists continue to push this research? (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - February 27, 2023 Category: Pharmaceuticals Authors: Steven Salzberg, Contributor Tags: Healthcare /healthcare Innovation /innovation Source Type: news

Lab Leak Most Likely Caused Pandemic, Energy Dept. Says
The conclusion, which was made with “low confidence,” came as America’s intelligence agencies remained divided over the origins of the coronavirus. (Source: NYT Health)
Source: NYT Health - February 27, 2023 Category: Consumer Health News Authors: Julian E. Barnes Tags: Coronavirus (2019-nCoV) Espionage and Intelligence Services United States Politics and Government Energy Department Federal Bureau of Investigation Wuhan Institute of Virology (China) Biden, Joseph R Jr Haines, Avril D Source Type: news

Long-acting antiretroviral therapy suppresses HIV among people with unstable housing, mental illnesses, substance use disorder
A long-acting antiretroviral treatment given every four to eight weeks, and delivered with comprehensive support services, suppressed HIV in people who were previously not virologically suppressed. (Source: National Institute of Mental Health)
Source: National Institute of Mental Health - February 21, 2023 Category: Psychiatry Authors: National Institute of Mental Health Source Type: news

Case studies expose deadly risk of mpox in people with untreated HIV
In June 2022, a young man in his 30s severely sick with mpox, the viral disease formerly known as monkeypox, was admitted to the Salvador Zubirán National Institute of Health Sciences and Nutrition hospital in Mexico City. Tests showed the patient was also HIV-positive, which he had not known, and that his blood had few CD4 cells, critical immune cells that HIV attacks. The man’s immune system was so weak it could not keep mpox in check and painful lesions kept spreading across his body, eating away at, or necrotizing, the flesh, according to HIV researcher Brenda Crabtree Ramirez, who was on his care team. Then the vir...
Source: ScienceNOW - February 21, 2023 Category: Science Source Type: news

Alcohol use, suicidality and virologic non-suppression among young adults with perinatally acquired HIV in Thailand: a cross-sectional study - Aurpibul L, Kosalaraksa P, Kawichai S, Lumbiganon P, Ounchanum P, Natalie Songtaweesin W, Sudjaritruk T, Chokephaibulkit K, Rungmaitree S, Suwanlerk T, Ross JL, Sohn AH, Puthanakit T.
This study assessed health risk behaviours (including substance use), mental health, quality of life (QOL) and HIV treatment outcomes of Thai YA-PHIV. ... (Source: SafetyLit)
Source: SafetyLit - February 20, 2023 Category: International Medicine & Public Health Tags: Age: Young Adults Source Type: news

Mechanisms of Reciprocal Interactions between HIV Associated Neuroinflammation and Central Nervous System (CNS) Persistence: Implications in HIV Neuropathogenesis and Cure
The goal of this concept is to examine mechanisms of reciprocal interactions between HIV-associated neuroinflammation and central nervous system (CNS) persistence in the setting of excellent virologic control using novel CNS cell systems, organoid models, and single-cell technologies. (Source: National Institute of Mental Health)
Source: National Institute of Mental Health - February 14, 2023 Category: Psychiatry Authors: National Institute of Mental Health Source Type: news

Bird flu warning as top experts say world is 'nowhere near' ready for inevitable pandemic
Cases of the killer H5N1 strain have already jumped from birds to mammals in the UK, sparking concern among virologists that the deadly pathogen is now closer to spreading in humans. (Source: the Mail online | Health)
Source: the Mail online | Health - February 10, 2023 Category: Consumer Health News Source Type: news

Bird Flu Isn ’t a Danger to Humans … Yet
Bird flu appears to be on the move. A particularly nasty strain of the H5N1 virus is currently causing the worst outbreak of the disease among birds since it was first identified in China in 1996. Europe is deep into its second commercial season of widespread contagion, and the U.S. is seeing its deadliest 12-month period for poultry in recorded history, with 58 million animals affected so far. Records are also being broken in Japan, where a plan to cull 10 million poultry was announced in mid-January amid the appearance of a different but similar subtype, H5N2. [time-brightcove not-tgx=”true”] The past few yea...
Source: TIME: Health - February 9, 2023 Category: Consumer Health News Authors: Haley Weiss Tags: Uncategorized Disease Explainer healthscienceclimate Source Type: news

Expert Panel Recommends Restrictions On Dangerous Gain-Of-Function Research. Virologists Are Already Pushing Back
This past week, a government-appointed panel of scientists released a new report recommending 13 things the government should do to control “gain-of-function” research that has the potential to create deadly new pathogens. Will any of these new ideas be adopted? We'll see. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - February 6, 2023 Category: Pharmaceuticals Authors: Steven Salzberg, Contributor Tags: Healthcare /healthcare Innovation /innovation Source Type: news