Trial By Error: Interview with Founders of The Sick Times, a New Online Publication
By David Tuller, DrPH Earlier this month, Betsy Ladyzhets and Miles Griffis, two smart, young American journalists, announced the launch The Sick Times, an online publication focused on long Covid and related post-acute infection syndromes, including ME/CFS. I have met both of them in the last couple of years and have been impressed with their … Trial By Error: Interview with Founders of The Sick Times, a New Online Publication Read More » (Source: virology blog)
Source: virology blog - November 24, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized griffis Ladyzhets Long Covid sick times Source Type: blogs

Trial By Error: Column in Time Magazine Calls for Halt to Biomedical Long Covid Research
By David Tuller, DrPH *This is a crowdfunding month at UC Berkeley for my Trial by Error project. If you appreciate my work and would like to help support it, here’s the link for the November campaign. Time magazine recently published an opinion piece that calls for an end to biomedical research for long Covid—based, it seems, … Trial By Error: Column in Time Magazine Calls for Halt to Biomedical Long Covid Research Read More » (Source: virology blog)
Source: virology blog - November 21, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized time magazine Source Type: blogs

Trial By Error: Cochrane Ends Silence on ME/CFS Exercise Review Developments
By David Tuller, DrPH *This is a crowdfunding month at UC Berkeley for my Trial by Error project. If you appreciate my work and would like to help support it, here’s the link for this November’s campaign. I recently posted about Cochrane’s unsatisfactory responses to a request from the Science for ME forum that the organization withdraw … Trial By Error: Cochrane Ends Silence on ME/CFS Exercise Review Developments Read More » (Source: virology blog)
Source: virology blog - November 17, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized cochrane exercise review science for ME Source Type: blogs

Trial By Error: Yet More Stupidity from the Dutch CBT Fan Club
By David Tuller, DrPH *This is a crowdfunding month at UC Berkeley for my Trial by Error project. If you appreciate my work and would like to help support it, here’s the link for this November’s campaign. As I pointed out last month when I reviewed a ridiculous study of “psychosomatic therapy” for “persistent somatic symptoms,” the … Trial By Error: Yet More Stupidity from the Dutch CBT Fan Club Read More » (Source: virology blog)
Source: virology blog - November 12, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized CBT dutch meta-analysis systematic review Source Type: blogs

Trial By Error: A Conversation with Lisa McCorkell of the Patient-Led Research Collaborative
*This is a crowdfunding month at UC Berkeley for my Trial by Error project. If you appreciate my work and would like to help support it, here’s the link for this November’s campaign. By David Tuller, DrPH Lisa McCorkell is a co-founder of the Patient-Led Research Collaborative, a group of people with Long COVID and … Trial By Error: A Conversation with Lisa McCorkell of the Patient-Led Research Collaborative Read More » (Source: virology blog)
Source: virology blog - November 7, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized Lisa McCorkell Patient-led Research Collaborative Source Type: blogs

Trial By Error: Letter on Inflated FND Prevalence Rates Accepted for Publication
By David Tuller, DrPH As I have regularly noted, patients with diagnoses of functional neurological disorder (FND) experience tremendous suffering. A patient who goes by the moniker @FnDPortal has written a compelling and sometimes harrowing essay, Cadenza for Fractured Consciousness: A Personal History of the World’s Most Misunderstood Illness, that is well worth a read in … Trial By Error: Letter on Inflated FND Prevalence Rates Accepted for Publication Read More » (Source: virology blog)
Source: virology blog - November 2, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized FND functional neurological disorder neuroImage: clinical prevalence Stone et al Source Type: blogs

A Nobel Discovery
by Gertrud U. Rey On October 2nd, 2023, the Nobel Assembly at Karolinska Institutet announced the award of the 2023 Nobel Prize in Physiology or Medicine to Katalin Karikó and Drew Weissman. The decision was based on a series of fundamental discoveries that led to the development of the COVID-19 messenger RNA (mRNA) vaccines. Katalin … A Nobel Discovery Read More » (Source: virology blog)
Source: virology blog - November 2, 2023 Category: Virology Authors: Gertrud U. Rey Tags: Basic virology Gertrud Rey Drew Weissman Katalin Kariko modified nucleoside mRNA vaccine N1-methyl-pseudouridine Nobel Prize Source Type: blogs

Trial By Error: What ’ s Going On with Cochrane ’ s Exercise Review Mess?
By David Tuller On September 4th, the Science for ME (S4ME) forum sent an open letter to Cochrane’s editor-in-chief, Karla Soares-Weiser, requesting the “immediate withdrawal or retraction” of “Exercise therapy for chronic fatigue syndrome,” a 2019 review. The review over-stated the evidence in favor of exercise therapies and has been widely and appropriately criticized for … Trial By Error: What’s Going On with Cochrane’s Exercise Review Mess? Read More » (Source: virology blog)
Source: virology blog - October 28, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized cochrane exercise review petition science for ME Source Type: blogs

Trial By Error: A Crap Study on “ Psychosomatic Therapy ” for “ Persistent Somatic Symptoms ”
By David Tuller, DrPH *This post has been corrected. I initially wrote that the protocol did not appear to call for sub-group analyses, but it appears it did. I also included a passage about that is from documentation in the supplemental material. I had identified it as coming from the protocol. I apologize for the … Trial By Error: A Crap Study on “Psychosomatic Therapy” for “Persistent Somatic Symptoms” Read More » (Source: virology blog)
Source: virology blog - October 26, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized dutch persistent somatic symptoms psychsomatic therapy Source Type: blogs

Trial By Error: A Follow-Up on a Post About Whether Anxiety and Depression Perpetuate Functional Limb Weakness
By David Tuller, DrPH Zachary Grin, a physical therapist in New York City who specializes in treating patients with functional neurological disorder (FND), commented on my most recent blog after I posted a link to it on X, the social media platform formerly known as Twitter. As he noted in his series of tweets (or … Trial By Error: A Follow-Up on a Post About Whether Anxiety and Depression Perpetuate Functional Limb Weakness Read More » (Source: virology blog)
Source: virology blog - October 19, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized anxiety depression FND zachary grin Source Type: blogs

Trial By Error: Depression/Anxiety Not Linked to Negative Outcomes in Patients with Functional Limb Weakness, FND Experts Report
By David Tuller, DrPH The Journal of Psychosomatic Research has just published a paper called “The Impact of Depression, Anxiety and Personality Disorders on the Outcome of Patients with Functional Limb Weakness – Individual Patient Data Meta-Analysis.” As I have previously noted, the journal is something of a house organ for seriously flawed research from … Trial By Error: Depression/Anxiety Not Linked to Negative Outcomes in Patients with Functional Limb Weakness, FND Experts Report Read More » (Source: virology blog)
Source: virology blog - October 17, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized depression FND SNSS statistics Stone et al Source Type: blogs

Trial By Error: Authors of Dutch Long Covid Paper Contradict Each Other
By David Tuller, DrPH I have slammed a recent Dutch study, Kuut et al, that investigated CBT for fatigue after an acute bout of COVID-19. The study, “Efficacy of Cognitive-Behavioral Therapy Targeting Severe Fatigue Following Coronavirus Disease 2019: Results of a Randomized Controlled Trial,” nicknamed ReCOVer, was published in Clinical Infectious Diseases, a well-regarded journal, … Trial By Error: Authors of Dutch Long Covid Paper Contradict Each Other Read More » (Source: virology blog)
Source: virology blog - October 14, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized dutch Source Type: blogs

Trial By Error: More of the Same Old Nonsense from the “ Oslo Chronic Fatigue Consortium ”
By David Tuller, DrPH It is extremely dispiriting to have to respond to yet another wail of desperation from psychologizing dead-enders who have lost control of the narrative over the nature and treatment of ME/CFS and long Covid. This most recent screed, published last month in the Scandinavian Journal of Primary Health Care, has been … Trial By Error: More of the Same Old Nonsense from the “Oslo Chronic Fatigue Consortium” Read More » (Source: virology blog)
Source: virology blog - October 9, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized Landmark Lightning Process Oslo Scandinavian journal of primary health care Source Type: blogs

Trial By Error: Norwegian Lightning Process Trial Ejects Questioning Participant
By David Tuller, DrPH The administrators of a controversial study of the Lightning Process currently being conducted in Norway have ejected a participant who expressed critical views about the biopsychosocial approach to ME, according to MELivet [MELife], Nina Steinkopf’s invaluable blog. This decision appears to be an acknowledgement that the intervention only works if you … Trial By Error: Norwegian Lightning Process Trial Ejects Questioning Participant Read More » (Source: virology blog)
Source: virology blog - October 5, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized Crawley Lightning Process Nina Steinkopf norway Source Type: blogs

Viruses and Bats
by Gertrud U. Rey Remember the series of flashbacks in the ending of the movie “Contagion,” which reveal where the virus originated and how the pandemic started? As a tree is cut down, a colony of bats flies out of the tree to seek new shelter. While in flight over a nearby farm, one of … Viruses and Bats Read More » (Source: virology blog)
Source: virology blog - October 5, 2023 Category: Virology Authors: Gertrud U. Rey Tags: Basic virology Gertrud Rey ACE2 bat bats contagion coronavirus emergence emerging virus furin cleavage site host range outbreak pandemic reservoir reservoir host SARS SARS-CoV SARS-CoV-2 spillover surveillance zoono Source Type: blogs