Trial By Error: If Professor Crawley ’ s ACT Study Was Peer Reviewed, Where Are the Peer Reviews?
By David Tuller, DrPH Yesterday, I wrote a blog about a just-published but already out-dated conference abstract from a team led by Professor Esther Crawley, Bristol University’s methodologically and ethically challenged pediatrician and grant magnet. After I tweeted about it, I heard from Naomi Harvey, a zoologist, who said she’d written to BJPsychOpen about the […] (Source: virology blog)
Source: virology blog - July 12, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized acceptance and commitment therapy BMJ Crawley Source Type: blogs

Trial By Error: Professor Crawley Promotes Acceptance and Commitment Therapy for CBT Failures
By David Tuller, DrPH What is going on with Professor Esther Crawley, Bristol University’s methodologically and ethically challenged pediatrician and grant magnet? And why is she still disseminating misguided views about treatments for vulnerable children? Haven’t kids suffered enough from the discredited claims of the GET/CBT ideological brigades? Just last week, the East Kent Hospitals […] (Source: virology blog)
Source: virology blog - July 11, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized acceptance and commitment therapy Crawley Source Type: blogs

Trial By Error: A Letter About the Inflated Prevalence Rate of Functional Neurological Disorder
By David Tuller, DrPH I have recently written two posts (here and here) about how experts in functional neurological disorder (FND) have a tendency to assert prevalence rates that ignore their own diagnostic criteria. Today I sent a letter to the corresponding author of yet another paper that has similarly engaged in this problematic strategy. […] (Source: virology blog)
Source: virology blog - July 7, 2022 Category: Virology Authors: David Tuller Tags: David Tuller ME/CFS FND functional neurological disorder Source Type: blogs

Should we be worried about monkeypox?
Although monkeypox cases continue to increase around the world, the average person is at low risk of becoming infected. (Source: virology blog)
Source: virology blog - July 7, 2022 Category: Virology Authors: Gertrud U. Rey Tags: Basic virology Gertrud Rey Information acam2000 antiviral drug bifurcated needle bodily fluids brincidofovir fluid-filled vesicles Jynneos lesion men who have sex with men monkeypox MVA-BN Poxviridae ring vaccination sexual Source Type: blogs

Trial By Error: Sometimes Good Things Happen Quickly, Even When It Involves the UK National Health Service
By David Tuller, DrPH The new ME/CFS guidelines from the UK’s National Institute of Health and Care Excellence, published last October, reversed the agency’s previous recommendations for graded exercise therapy and (curative) cognitive behavior therapy. While this change presented a welcome repudiation of the research and claims emanating from the GET/CBT ideological brigades, many regional […] (Source: virology blog)
Source: virology blog - July 3, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized Charles Shepherd ME Association Source Type: blogs

TWiV 915: Mouse mouth to mouse mom
TWiV discusses the recent decision by an FDA advisory committee to update COVID vaccines for the fall, the monkeypox virus outbreak, and the finding that enteric viruses infect the salivary glands and are transmitted through saliva. (Source: virology blog)
Source: virology blog - July 3, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology coronavirus COVID-19 enteric virus norovirus pandemic rotavirus saliva saliva transmissions salivary gland SARS-CoV-2 vaccine variant of concern viral viruses Source Type: blogs

TWiEVO 79: When the immune system is away, SARS-CoV-2 will play
Nels and Vincent discuss an analysis of the drivers of evolution of SARS-CoV-2 during chronic infections, indicating that a tradeoff exists between antibody evasion and fitness. (Source: virology blog)
Source: virology blog - July 2, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Evolution antibody evasion chronic infection coronavirus COVID-19 fitness immunocompromised natural selection pandemic SARS-CoV-2 Source Type: blogs

TWiV 914: COVID-19 clinical update #121 with Dr. Daniel Griffin
In COVID-19 clinical update #121, Dr. Griffin discusses age as a risk factor for severe disease, updated vaccine boosters for the fall, pediatric infection and antibody seroprevalence in Arkansas over the first year of the COVID-19 pandemic, all-cause maternal mortality in the United States before and during the pandemic, and the effect of 2-week interruption in methotrexate treatment and how it impacts vaccine immunity. (Source: virology blog)
Source: virology blog - July 2, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antiviral coronavirus COVID-19 delta inflammation Long Covid monoclonal antibody Omicron pandemic SARS-CoV-2 vaccine vaccine booster variant of concern viruses Source Type: blogs

Trial By Error: An FND Patient ’ s View – and More on Those Inflated Prevalence Rates
By David Tuller, DrPH In a post last week, I noted that experts in FND have a tendency to assert prevalence rates that ignore their own diagnostic criteria. Before offering further thoughts on that score, I want to make one point very explicit: I am in no way questioning whether people with the diagnosis have […] (Source: virology blog)
Source: virology blog - June 22, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized Alan Carson FND functional neurological disorder Jon Stone Source Type: blogs

TWiV 911: Antibody can get vaccinated now
TWiV provides an update on hepatitis of unknown etiology in children, an experimental nanoparticle vaccine for Epstein-Barr virus, and minimal impact of bamlanivimab therapy on antiviral antibodies induced by vaccination. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Click arrow to playDownload TWiV 911 (76 MB .mp3, 127 min)Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Show […] (Source: virology blog)
Source: virology blog - June 20, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology bamlanivimab COVID-19 Epstein-Barr virus hepatitis nanoparticle vaccine pandemic SARS-CoV-2 viral viruses Source Type: blogs

TWiV 910: COVID-19 clinical update #119 with Dr. Daniel Griffin
In COVID-19 clinical update #119, Dr. Griffin reviews tixagevimab for infection prevention, ivermectin for outpatient infection treatment, symptom rebound after PAXLOVID treatment, bamlanivimab minimally impacting immune response to vaccination, in-hospital mortality among infection patients, residual viral antigen in patients following infection, usage of Casirvimab/Imdevimab and Remdesivir in infected patients with depleted B-cells, and rheumatic symptoms […] (Source: virology blog)
Source: virology blog - June 18, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antiviral coronavirus COVID-19 delta inflammation Long Covid monoclonal antibody pandemic SARS-CoV-2 vaccine vaccine booster variant of concern viruses Source Type: blogs

Trial By Error: Does Functional Neurology Disorder Account for a Third of Outpatient Neurology Consults?
By David Tuller, DrPH Functional neurological disorder, or FND, is the new-ish name for the hoary Freudian construct known as conversion disorder. For decades, psychiatrists informed patients that they were “converting” their emotional distress and anxieties into physical symptoms like tremors, seizures, sensory and cognitive deficits, a halting gait, or other physical dysfunctions. The impossibility […] (Source: virology blog)
Source: virology blog - June 16, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized FND functional neurological disorder Source Type: blogs

Trial By Error: A Reprise of an Earlier Blog Post About Godwin ’ s Law on Nazi Analogies and Simon Wessely
By David Tuller, DrPH In a new book, Fiona Fox, the head of the London-based Science Media Centre, has compared critics of the GET/CBT ideological brigades and the PACE trial to Nazis, as I noted recently on Virology Blog. In response to her unfortunate reference to the Holocaust in this context, some on social media […] (Source: virology blog)
Source: virology blog - June 7, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized Fiona Fox godwin's law mike godwin nazis science media centre Source Type: blogs

TWiV 906: Long COVID, giant viruses, and smallish pox
TWiV reviews human monkeypox infections, evidence for human Mimivrus infections, and incidence of long COVID in post-vaccine SARS-CoV-2 infections. (Source: virology blog)
Source: virology blog - June 5, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology Source Type: blogs

Trial By Error: Science Media Centre Chief Fiona Fox Compares ME/CFS Patient Advocates to Nazis
By David Tuller, DrPH I have called the PACE trial of graded exercise therapy (GET) and cognitive behavior therapy (CBT) for ME/CFS “a piece of crap.” As I have indicated over the years, I think the trial is an example of serious research misconduct. (Whether it meets legal definitions of “fraud” is beyond my professional […] (Source: virology blog)
Source: virology blog - June 4, 2022 Category: Virology Authors: David Tuller Tags: David Tuller ME/CFS Fiona Fox science media centre Source Type: blogs