Examining Meaningful Activity Engagement for Residents in Assisted Living (MAC-4-BSD)
Engagement in meaningful activity is beneficial for residents with dementia and is associated with improved mental health, feelings of social connectedness, and quality of life. Meaningful activity refers to activities that provide meaning and value to the person and are tailored to individualized interests and preferences. There is limited research that explores factors that influence engagement in meaningful activity for residents with dementia in assisted living settings. The purpose of this study was to examine factors associated with engagement in meaningful activity among residents with dementia in assisted living. (...
Source: Journal of the American Medical Directors Association - April 30, 2024 Category: Health Management Authors: Sarah D. Holmes, Susan Scherr, Erin O'Brien, Sorah Levy, Elizabeth Galik, Barbara Resnick Source Type: research
COVID-19 Pandemic and Stroke Care in Patients With Dementia Compared to Other Stroke Patients
The primary objective of this study was to examine the impact of the COVID-19 pandemic on the quality of stroke care for patients with preexisting dementia, compared with patients who had only stroke. The secondary aim was to investigate how the quality of stroke care changed during the pandemic and post-pandemic periods compared with the pre-pandemic period in patients with preexisting dementia. (Source: Journal of the American Medical Directors Association)
Source: Journal of the American Medical Directors Association - April 30, 2024 Category: Health Management Authors: Tamar Abzhandadze, Minh Tuan Hoang, Minjia Mo, Shayan Mostafaei, Pol Grau Jurado, Hong Xu, Kristina Johnell, Mia Von Euler, Maria Eriksdotter, Sara Garcia-Ptacek Tags: Original Study Source Type: research
Oral anticoagulants and cognitive impairment in patients with atrial fibrillation: A systematic review with meta-analysis and trial sequential analysis
This systematic review assesses the likelihood of developing dementia and cognitive impairment in patients with atrial fibrillation (AF) receiving non-vitamin K antagonist oral anticoagulants (NOACs) as opposed to vitamin K antagonists (VKAs). (Source: Thrombosis Research)
Source: Thrombosis Research - April 30, 2024 Category: Hematology Authors: Kun-Han Lee, Jiunn-Tyng Yeh, Meng-Lun Wu, Wan-Yu Yeh, Gregory Y.H. Lip, Chern-En Chiang, Chen-Huan Chen, Hao-Min Cheng Source Type: research
IJERPH, Vol. 21, Pages 575: The Architectural Layout of Long-Term Care Units: Relationships between Support for Residents & rsquo; Well-Being and for Caregivers & rsquo; Burnout and Resilience
This study aimed to investigate correlations between the support provided by the architectural layout of long-term care units for enhancing residents’ well-being and for decreasing unit caregivers’ burnout and increasing their resilience—as layouts may impact each party differently. The Psycho Spatial Evaluation Tool was utilized to assess the support provided by the layouts of seventeen long-term care units (ten regular nursing units and seven specialized dementia units) for the residents’ physical and social well-being (five dimensions); a questionnaire was used to ...
Source: International Journal of Environmental Research and Public Health - April 30, 2024 Category: Environmental Health Authors: Yifat Rom Ido Morag Yuval Palgi Michal Isaacson Tags: Article Source Type: research
Large-Scale Normative Modeling of Brain Microstructure
Normative models of brain metrics based on large populations are extremely valuable for detecting brain abnormalities in patients with dementia, psychiatric, or developmental conditions. (Source: Biological Psychiatry)
Source: Biological Psychiatry - April 29, 2024 Category: Psychiatry Authors: Julio Villal ón-Reina, Alyssa Zhu, Talia Nir, Sophia Thomopoulos, Emily Laltoo, Carrie Bearden, Neda Jahanshad, Paul M. Thompson Source Type: research
380. A Hypomorphic TBK1 N455S Variant in a Woman With Post-Infectious Refractory Psychosis and Catatonia
TANK-binding kinase 1 (TBK1) missense mutations predispose to neurologic disease including frontotemporal dementia and amyotrophic lateral sclerosis (FTD-ALS). FTD-ALS TBK1 variants have also been observed in patients with a primary schizophrenia diagnosis. TBK1 upregulates the transcription of type I interferon genes in response to bacteria including B. burgdorferi, which causes Lyme disease. Among the many functional consequences of TBK1 missense variants, a reduction in protein expression by more than 50% is considered pathogenic. (Source: Biological Psychiatry)
Source: Biological Psychiatry - April 29, 2024 Category: Psychiatry Authors: Jailyn M. Izu, GenaLynne C. Mooneyham, Thomas T. Ngo, Samuel J. Pleasure, Michael R. Wilson, Avindra Nath, Christopher M. Bartley Source Type: research
173. Associations Between Cytochrome P450 - Soluble Epoxide Hydrolase Pathway Oxylipins and Cognition in People With Depressive Symptoms and Type 2 Diabetes
This study examines interactions between epoxides and diols ( “oxylipins”) and depressive symptoms in predicting cognitive performance in participants with T2D. (Source: Biological Psychiatry)
Source: Biological Psychiatry - April 29, 2024 Category: Psychiatry Authors: Natasha Z. Anita, Nathan Herrmann, Si Won Ryoo, Chelsi Major-Orfao, William Z. Lin, Felicia Kwan, Shiropa Noor, Jennifer Rabin, Susan Marzolini, Sean Nestor, Myuri Ruthirakuhan, Bradley J. MacIntosh, Maged Goubran, Pearl Yang, Hugo Cogo-Moreira, Mark Rapo Source Type: research
145. Geriatric Depressive Patients May Have Dementia That is Not Being Recognized
Dementia and depression can have similar symptoms, and depression is more common in elderly patients with dementia. It's important to differentiate between the two through diagnosis. (Source: Biological Psychiatry)
Source: Biological Psychiatry - April 29, 2024 Category: Psychiatry Authors: David Guerra Medellin, Ricardo Ruiz Mesa, Alfonso Ontiveros, Guillermo Sanchez Torres, Luis Alberto De La Garza Garcia, Sofia Jezzini Martinez, Jaime Martinez Velazquez, Felipe Sandoval Aviles Source Type: research
147. Diffuse Optical Tomography for Mapping Cerebral Hemodynamics and Functional Connectivity in Delirium
Delirium is associated with mortality and new onset dementia, yet the underlying pathophysiology remains poorly understood. Development of imaging biomarkers has been difficult given the challenging nature of imaging delirious patients. Diffuse optical tomography (DOT) offers a promising approach for investigating delirium given its portability and three-dimensional capabilities. (Source: Biological Psychiatry)
Source: Biological Psychiatry - April 29, 2024 Category: Psychiatry Authors: Shixie (Max) Jiang, Jingyu Huang, Hao Yang, Richard Czuma, Lauren Farley, Alexis Cohen-Oram, Kimberly Hartney, Kristina Chechotka, F. Andrew Kozel, Huabei Jiang Source Type: research
Evaluation of a Digital Dementia Registry's IT Architecture After a Three-Year Period in Practice: digiDEM Bayern
CONCLUSION: Integrating the used systems is therefore recommended for registry studies in other medical areas.PMID:38682503 | DOI:10.3233/SHTI240010 (Source: Studies in Health Technology and Informatics)
Source: Studies in Health Technology and Informatics - April 29, 2024 Category: Information Technology Authors: Michael Zeiler Nikolas Dietzel Peter L Kolominsky-Rabas Elmar Graessel Hans-Ulrich Prokosch Source Type: research
Enhancing Dementia Risk Mitigation: Standardized Digital Monitoring in Clinical Trials and Platform Design for At-Risk Elderly Individuals
CONCLUSION: The interoperability framework was designed in a scalable way and will be regularly updated for future needs.PMID:38682497 | DOI:10.3233/SHTI240004 (Source: Studies in Health Technology and Informatics)
Source: Studies in Health Technology and Informatics - April 29, 2024 Category: Information Technology Authors: Hannes Hilberger Bianca Buchgraber-Schnalzer Simone Huber Theresa Weitlaner Helena Untersteiner Carina Seerainer Sten Hanke Source Type: research
Thalamic Alterations in Motor Neuron Diseases: A Systematic Review of MRI Findings
CONCLUSIONS: Thalamic alterations provide valuable insights into the pathophysiology and progression of MNDs. Multimodal MRI techniques are potent tools for detecting dynamic thalamic changes, indicating structural integrity, connectivity disruption, and metabolic activity.PMID:38682227 | DOI:10.31083/j.jin2304077 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - April 29, 2024 Category: Neuroscience Authors: Sana Mohammadi Sadegh Ghaderi Mahdi Mohammadi Zahra Najafi Asli Pashaki Rahim Khatyal Fatemeh Mohammadian Sahar Mohammadjani Source Type: research
Pharmacotherapeutic Potential of Bitter Gourd ( < em > Momordica charantia < /em > ) in Age-related Neurological Diseases
J Integr Neurosci. 2024 Apr 23;23(4):86. doi: 10.31083/j.jin2304086.ABSTRACTDue to the growth of the elderly population, age-related neurological disorders are an increasing problem. Aging begins very gradually and later leads to several neurological issues such as lower neurotransmitter levels, oxidative stress, neuronal inflammation, and continual neuronal loss. These changes might contribute to brain disorders such as Alzheimer's disease (AD), dementia or mild cognitive impairment, and epilepsy and glioma, and can also aggravate these disorders if they were previously present. Momordica charantia (bitter gourd), a membe...
Source: Journal of Integrative Neuroscience - April 29, 2024 Category: Neuroscience Authors: Seyed Mohammad Hosein Hosseini Adarmanabadi Orod Jalali Khalil Abadi Amirhossein Amiri Rozhina Tamannaeifar Sahar Balanian Mehdi Rasekhjam Mohammad Sadra Samiazar Sara Hasanpour Samira Peiravi Dorsa Alijanzadeh Mohadeseh Poudineh Hamidreza Amiri Seyed Ami Source Type: research
Microvascular Perfusion Imaging in Alzheimer's Disease
J Integr Neurosci. 2024 Apr 1;23(4):70. doi: 10.31083/j.jin2304070.ABSTRACTAlzheimer's disease (AD) is the leading cause of dementia worldwide and significantly impacts the essential functions of daily life and social activities. Research on AD has found that its pathogenesis is related to the extracellular accumulation of amyloid-beta (Aβ) plaques and intracellular neurofibrillary tangles in the cortical and limbic areas of the human brain, as well as cerebrovascular factors. The detection of Aβ or tau can be performed using various probes and methodologies. However, these modalities are expensive to implement and often...
Source: Journal of Integrative Neuroscience - April 29, 2024 Category: Neuroscience Authors: Yi Song Hang Xing Zhiqi Zhang Source Type: research
Symptom burden, service use and care dissatisfaction among older adults with cancer, cardiovascular disease, respiratory disease, dementia and neurological disease during the last 3 months before death: A pooled analysis of mortality follow-back surveys
CONCLUSIONS: We showed different trajectories towards death depending on cause. Improving symptom burden and satisfaction in patients at the end-of-life is challenging, and the presence of a reliable key health professional may be helpful.PMID:38679837 | DOI:10.1177/02692163241246049 (Source: Palliative Medicine)
Source: Palliative Medicine - April 29, 2024 Category: Palliative Care Authors: Mitsunori Miyashita Catherine J Evans Deokee Yi Barbara Gomes Wei Gao Source Type: research
