Aging Clinical and Experimental Research 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog."The least significant change on bone mineral density scan increased in patients with higher degrees of obesity"
CONCLUSION: LSC of 0.05 g/cm² could be used in clinical practice in patients with class 2 or 3 obesity. These findings should help to improve the interpretation of BMD scans in these patients and optimize their management.TRIAL REGISTRATION NUMBER: Comité de Protection des Personnes Ile-de France VII, France.PMID:38652346 | PMC:PMC11039528 | DOI:10.1007/s40520-024-02736-4 (Source: Aging Clinical and Experimental Research)
Source: Aging Clinical and Experimental Research - April 23, 2024 Category: Geriatrics Authors: Claire Dorilleau Lukshe Kanagaratnam Isabelle Charlot Ambre Hittinger Eric Bertin Jean-Hugues Salmon Marion Geoffroy Source Type: research
Commentary on: physical activity and exercise for mild cognitive impairment and dementia: a collaborative international guideline
In conclusion, there is limited evidence on the beneficial role of physical activity and exercise in preserving cognitive functions in subjects with normal cognition, MCI or dementia. The guidelines support the promotion of physical activity based on the beneficial effects on almost all facets of health.PMID:38652380 | PMC:PMC11039492 | DOI:10.1007/s40520-024-02747-1 (Source: Aging Clinical and Experimental Research)
Source: Aging Clinical and Experimental Research - April 23, 2024 Category: Geriatrics Authors: Nicola Veronese Pinar Soysal Mario Barbagallo Susan D Shenkin Terence J Quinn Source Type: research
"The least significant change on bone mineral density scan increased in patients with higher degrees of obesity"
CONCLUSION: LSC of 0.05 g/cm² could be used in clinical practice in patients with class 2 or 3 obesity. These findings should help to improve the interpretation of BMD scans in these patients and optimize their management.TRIAL REGISTRATION NUMBER: Comité de Protection des Personnes Ile-de France VII, France.PMID:38652346 | PMC:PMC11039528 | DOI:10.1007/s40520-024-02736-4 (Source: Aging Clinical and Experimental Research)
Source: Aging Clinical and Experimental Research - April 23, 2024 Category: Geriatrics Authors: Claire Dorilleau Lukshe Kanagaratnam Isabelle Charlot Ambre Hittinger Eric Bertin Jean-Hugues Salmon Marion Geoffroy Source Type: research
Commentary on: physical activity and exercise for mild cognitive impairment and dementia: a collaborative international guideline
In conclusion, there is limited evidence on the beneficial role of physical activity and exercise in preserving cognitive functions in subjects with normal cognition, MCI or dementia. The guidelines support the promotion of physical activity based on the beneficial effects on almost all facets of health.PMID:38652380 | PMC:PMC11039492 | DOI:10.1007/s40520-024-02747-1 (Source: Aging Clinical and Experimental Research)
Source: Aging Clinical and Experimental Research - April 23, 2024 Category: Geriatrics Authors: Nicola Veronese Pinar Soysal Mario Barbagallo Susan D Shenkin Terence J Quinn Source Type: research
"The least significant change on bone mineral density scan increased in patients with higher degrees of obesity"
CONCLUSION: LSC of 0.05 g/cm² could be used in clinical practice in patients with class 2 or 3 obesity. These findings should help to improve the interpretation of BMD scans in these patients and optimize their management.TRIAL REGISTRATION NUMBER: Comité de Protection des Personnes Ile-de France VII, France.PMID:38652346 | DOI:10.1007/s40520-024-02736-4 (Source: Aging Clinical and Experimental Research)
Source: Aging Clinical and Experimental Research - April 23, 2024 Category: Geriatrics Authors: Claire Dorilleau Lukshe Kanagaratnam Isabelle Charlot Ambre Hittinger Eric Bertin Jean-Hugues Salmon Marion Geoffroy Source Type: research
Commentary on: physical activity and exercise for mild cognitive impairment and dementia: a collaborative international guideline
In conclusion, there is limited evidence on the beneficial role of physical activity and exercise in preserving cognitive functions in subjects with normal cognition, MCI or dementia. The guidelines support the promotion of physical activity based on the beneficial effects on almost all facets of health.PMID:38652380 | DOI:10.1007/s40520-024-02747-1 (Source: Aging Clinical and Experimental Research)
Source: Aging Clinical and Experimental Research - April 23, 2024 Category: Geriatrics Authors: Nicola Veronese Pinar Soysal Mario Barbagallo Susan D Shenkin Terence J Quinn Source Type: research
Comments on the methodology and completeness of a meta-analysis on the association between social frailty and adverse outcomes
Aging Clin Exp Res. 2024 Apr 19;36(1):97. doi: 10.1007/s40520-024-02741-7.NO ABSTRACTPMID:38639800 | PMC:PMC11031434 | DOI:10.1007/s40520-024-02741-7 (Source: Aging Clinical and Experimental Research)
Source: Aging Clinical and Experimental Research - April 19, 2024 Category: Geriatrics Authors: Xiao-Ming Zhang Zhe Yang Source Type: research
Predicting the efficacy of donepezil intervention in Alzheimer's disease patients using regional homogeneity in the inferior orbitofrontal cortex
CONCLUSIONS: These findings deepen our understanding of the brain mechanisms underlying the clinical efficacy of donepezil in AD patients, and provide a novel way to predict its clinical efficacy in such patients.PMID:38630202 | PMC:PMC11024046 | DOI:10.1007/s40520-023-02691-6 (Source: Aging Clinical and Experimental Research)
Source: Aging Clinical and Experimental Research - April 17, 2024 Category: Geriatrics Authors: Min Dai Zhongwei Guo Honglian Xia Hong Zhu Jiapeng Li Hongtao Hou Guizhi Zhao Xiaozheng Liu Source Type: research
Association of serum uric acid with functional disability in older subjects: a population-based study
CONCLUSIONS: In older subjects, SUA levels are associated with disability; the cut off level above 5.5 mg/dL might be adopted in pharmacological trials aiming at reducing the incidence and progression of disability by reducing SUA, and for identifying subjects at increased risk of disability.PMID:38630352 | PMC:PMC11023951 | DOI:10.1007/s40520-024-02746-2 (Source: Aging Clinical and Experimental Research)
Source: Aging Clinical and Experimental Research - April 17, 2024 Category: Geriatrics Authors: Alice Laudisio Agnese Dorizzi Fabio Villeggia Francesca Latino Daniele Filippucci Giuseppe Zuccal à Source Type: research
Combining Mini-Mental State Examination and Montreal Cognitive Assessment for assessing the clinical efficacy of cholinesterase inhibitors in mild Alzheimer's disease: a pilot study
Aging Clin Exp Res. 2024 Apr 17;36(1):95. doi: 10.1007/s40520-024-02744-4.ABSTRACTCurrent drugs for Alzheimer's Disease (AD), such as cholinesterase inhibitors (ChEIs), exert only symptomatic activity. Different psychometric tools are needed to assess cognitive and non-cognitive dimensions during pharmacological treatment. In this pilot study, we monitored 33 mild-AD patients treated with ChEIs. Specifically, we evaluated the effects of 6 months (Group 1 = 17 patients) and 9 months (Group 2 = 16 patients) of ChEIs administration on cognition with the Mini-Mental State Examination (MMSE), the Montreal Cognitive Assessment (...
Source: Aging Clinical and Experimental Research - April 17, 2024 Category: Geriatrics Authors: Giovanna Furneri Simone Varrasi Claudia Savia Guerrera Giuseppe Alessio Platania Vittoria Torre Francesco Maria Boccaccio Maria Federica Testa Federica Martelli Alessandra Privitera Grazia Razza Mario Santagati Santo Di Nuovo Concetta Pirrone Sabrina Cast Source Type: research
Predicting the efficacy of donepezil intervention in Alzheimer's disease patients using regional homogeneity in the inferior orbitofrontal cortex
CONCLUSIONS: These findings deepen our understanding of the brain mechanisms underlying the clinical efficacy of donepezil in AD patients, and provide a novel way to predict its clinical efficacy in such patients.PMID:38630202 | DOI:10.1007/s40520-023-02691-6 (Source: Aging Clinical and Experimental Research)
Source: Aging Clinical and Experimental Research - April 17, 2024 Category: Geriatrics Authors: Min Dai Zhongwei Guo Honglian Xia Hong Zhu Jiapeng Li Hongtao Hou Guizhi Zhao Xiaozheng Liu Source Type: research
Association of serum uric acid with functional disability in older subjects: a population-based study
CONCLUSIONS: In older subjects, SUA levels are associated with disability; the cut off level above 5.5 mg/dL might be adopted in pharmacological trials aiming at reducing the incidence and progression of disability by reducing SUA, and for identifying subjects at increased risk of disability.PMID:38630352 | DOI:10.1007/s40520-024-02746-2 (Source: Aging Clinical and Experimental Research)
Source: Aging Clinical and Experimental Research - April 17, 2024 Category: Geriatrics Authors: Alice Laudisio Agnese Dorizzi Fabio Villeggia Francesca Latino Daniele Filippucci Giuseppe Zuccal à Source Type: research
Combining Mini-Mental State Examination and Montreal Cognitive Assessment for assessing the clinical efficacy of cholinesterase inhibitors in mild Alzheimer's disease: a pilot study
Aging Clin Exp Res. 2024 Apr 17;36(1):95. doi: 10.1007/s40520-024-02744-4.ABSTRACTCurrent drugs for Alzheimer's Disease (AD), such as cholinesterase inhibitors (ChEIs), exert only symptomatic activity. Different psychometric tools are needed to assess cognitive and non-cognitive dimensions during pharmacological treatment. In this pilot study, we monitored 33 mild-AD patients treated with ChEIs. Specifically, we evaluated the effects of 6 months (Group 1 = 17 patients) and 9 months (Group 2 = 16 patients) of ChEIs administration on cognition with the Mini-Mental State Examination (MMSE), the Montreal Cognitive Assessment (...
Source: Aging Clinical and Experimental Research - April 17, 2024 Category: Geriatrics Authors: Giovanna Furneri Simone Varrasi Claudia Savia Guerrera Giuseppe Alessio Platania Vittoria Torre Francesco Maria Boccaccio Maria Federica Testa Federica Martelli Alessandra Privitera Grazia Razza Mario Santagati Santo Di Nuovo Concetta Pirrone Sabrina Cast Source Type: research
Long-term trajectories of peak expiratory flow rate in older men and women show linear decline mainly determined by baseline levels
CONCLUSIONS: Trajectories in both men and women differ mainly in baseline level of PEFR and not in rate of decline over time. Therefore, one PEFR measurement might be sufficient to give an indication of the trajectory that an older adult is likely to follow.PMID:38627297 | PMC:PMC11021284 | DOI:10.1007/s40520-024-02735-5 (Source: Aging Clinical and Experimental Research)
Source: Aging Clinical and Experimental Research - April 16, 2024 Category: Geriatrics Authors: Natasja M van Schoor Renate T de Jongh Paul Lips Dorly J H Deeg Almar A L Kok Source Type: research
Serum klotho levels and mortality patterns in frail individuals: unraveling the u-shaped association
CONCLUSION: This study unveils a U shaped association between serum α-klotho levels and both all-cause and cancer-related mortality among middle-aged and elderly individuals with frailty in the United States. The identified serum α-klotho thresholds, at 714.8 pg/ml for all-cause mortality and 750.6 pg/ml for cancer-related mortality, hold promise as potential targets for interventions aimed at mitigating the risks of premature death and cancer within this vulnerable population.PMID:38602574 | PMC:PMC11008069 | DOI:10.1007/s40520-024-02730-w (Source: Aging Clinical and Experimental Research)
Source: Aging Clinical and Experimental Research - April 11, 2024 Category: Geriatrics Authors: Huanhuan Luo Zitian Zheng Huixiu Hu Chao Sun Source Type: research
