The estimation of a preference-based single index for the IBS-QoL by mapping to the EQ-5D-5L in patients with irritable bowel syndrome
ConclusionThis study reports the development of an algorithm where the condition-specific questionnaire IBS-QoL can be used to calculate utility values for use in economic evaluations. Including a clinical measure, IBS-SSS, in the model improved the performance of the algorithm. (Source: Quality of Life Research)
Source: Quality of Life Research - September 21, 2021 Category: Health Management Source Type: research

Health-related quality of life among breast cancer patients compared to cancer survivors and age-matched women in the general population in Vietnam
This study compared the health-related quality of life (HRQoL) of breast cancer (BC) patients, survivors, and age-matched women from the general population in Vietnam to address the paucity of HRQoL research and contribute to the robust assessment of BC screening and care in Vietnam.MethodsThe standardised EQ-5D-5L instrument was incorporated in an online survey and a hospital-based face-to-face survey, and together with data from the Vietnam EQ-5D-5L norms study.χ2 tests assessed EQ-5D health profile associations and a Tobit regression model investigated the association between overall health status (EQ-VAS/utility sc...
Source: Quality of Life Research - September 20, 2021 Category: Health Management Source Type: research

Psychometric properties of the spinal cord injury-quality of life (SCI-QOL) Resilience item bank in a sample with spinal cord injury and chronic pain
ConclusionThe SCI-QOL Resilience CAT demonstrated good convergent and discriminant validity. The CAT administration characteristics were impressive: With few items (low response burden), the scale achieved good reliability. (Source: Quality of Life Research)
Source: Quality of Life Research - September 20, 2021 Category: Health Management Source Type: research

Family quality of life for families of children with disabilities in African contexts: a scoping review
ConclusionWhilst there are universal factors that contribute to FQOL, recognising the influence of context-specific factors (i.e. poverty, stigma, spirituality) is important in order to provide effective, culturally relevant support that enhances FQOL for families of children with disabilities in African contexts. (Source: Quality of Life Research)
Source: Quality of Life Research - September 18, 2021 Category: Health Management Source Type: research

The association of body mass index with quality of life and working ability: a Finnish population-based study
This study investigated the association of obesity with QoL and working ability in Finnish adults. Comorbidities as associative factors were also characterised.MethodsThis cross-sectional study included 4956 randomly selected adults. QoL (EUROHIS-QOL 8 total score and individual components), perceived physical and psychological working ability, and sick leave days were analysed in different body mass index (BMI) groups. Regression models were used to study the role of comorbidities as associative factors.ResultsEUROHIS-QOL 8 total score was significantly lower in BMI group 25.0 –29.9 kg/m2 (4.01; 95% confidence ...
Source: Quality of Life Research - September 17, 2021 Category: Health Management Source Type: research

Patient-level barriers and facilitators to completion of patient-reported outcomes measures
ConclusionsThere are multiple distinct patient-level factors that affect PROM completion. Failure to consider these factors in PROM design and implementation may lower completion rates or prevent accurate completion, undermining PROM validity. Because certain factors affect minority populations at disproportionate rates, this may also contribute to existing health disparities. (Source: Quality of Life Research)
Source: Quality of Life Research - September 17, 2021 Category: Health Management Source Type: research

Improving respiratory muscle strength and health status in burn patients: a randomized controlled trial
AbstractPurposePulmonary complications are among the major disadvantages of burns. The present study aimed to determine the effect of inspiratory muscle training on respiratory muscle strength and health status in burned patients.MethodsThe current randomized clinical trial was conducted on 64 burned patients in Burn Center of Imam Reza Hospital, Mashhad, Iran. In the intervention group, a Powerbreathe device (KH1 digital model) was used twice a day for 10  days, accompanied by the routine procedures and in the control group, only chest physiotherapy and incentive spirometer were used.ResultsBefore the intervention, t...
Source: Quality of Life Research - September 17, 2021 Category: Health Management Source Type: research

The association of body mass index with quality of life and working ability: a Finnish population-based study
This study investigated the association of obesity with QoL and working ability in Finnish adults. Comorbidities as associative factors were also characterised.MethodsThis cross-sectional study included 4956 randomly selected adults. QoL (EUROHIS-QOL 8 total score and individual components), perceived physical and psychological working ability, and sick leave days were analysed in different body mass index (BMI) groups. Regression models were used to study the role of comorbidities as associative factors.ResultsEUROHIS-QOL 8 total score was significantly lower in BMI group 25.0 –29.9 kg/m2 (4.01; 95% confidence ...
Source: Quality of Life Research - September 17, 2021 Category: Health Management Source Type: research

Patient-level barriers and facilitators to completion of patient-reported outcomes measures
ConclusionsThere are multiple distinct patient-level factors that affect PROM completion. Failure to consider these factors in PROM design and implementation may lower completion rates or prevent accurate completion, undermining PROM validity. Because certain factors affect minority populations at disproportionate rates, this may also contribute to existing health disparities. (Source: Quality of Life Research)
Source: Quality of Life Research - September 17, 2021 Category: Health Management Source Type: research

Association of high adherence to vegetables and fruits dietary pattern with quality of life among Chinese women with early-stage breast cancer
ConclusionThis study suggested that high adherence to “grain and animal food pattern” or “vegetables and fruits pattern” was significantly associated with several aspects of QoL. For instance, vegetables and fruits pattern appears to have beneficial effect on global health status/QoL among Chinese breast cancer patients. Prospective follow-up d ata could further confirm whether a specific dietary pattern has impact on cancer outcomes. (Source: Quality of Life Research)
Source: Quality of Life Research - September 16, 2021 Category: Health Management Source Type: research

Happiness and depression in psoriasis: a cross-sectional study in Germany
ConclusionThe results of this study empirically supported the differentiation of subjective well-being and depression as different constructs in individuals with psoriasis, and underline the large mental burden of the disease which goes beyond a higher risk for depression. Measures of well-being should thus be incorporated in both research and clinical practice in patients with psoriasis in order to achieve a more comprehensive picture of the mental burden of this disease. (Source: Quality of Life Research)
Source: Quality of Life Research - September 16, 2021 Category: Health Management Source Type: research

Association of high adherence to vegetables and fruits dietary pattern with quality of life among Chinese women with early-stage breast cancer
ConclusionThis study suggested that high adherence to “grain and animal food pattern” or “vegetables and fruits pattern” was significantly associated with several aspects of QoL. For instance, vegetables and fruits pattern appears to have beneficial effect on global health status/QoL among Chinese breast cancer patients. Prospective follow-up d ata could further confirm whether a specific dietary pattern has impact on cancer outcomes. (Source: Quality of Life Research)
Source: Quality of Life Research - September 16, 2021 Category: Health Management Source Type: research

Happiness and depression in psoriasis: a cross-sectional study in Germany
ConclusionThe results of this study empirically supported the differentiation of subjective well-being and depression as different constructs in individuals with psoriasis, and underline the large mental burden of the disease which goes beyond a higher risk for depression. Measures of well-being should thus be incorporated in both research and clinical practice in patients with psoriasis in order to achieve a more comprehensive picture of the mental burden of this disease. (Source: Quality of Life Research)
Source: Quality of Life Research - September 16, 2021 Category: Health Management Source Type: research

Posttraumatic growth and well-being among people living with HIV: A systematic review and meta-analysis in recognition of 40  years of HIV/AIDS
ConclusionsThe present meta-analysis and systematic review revealed expected negative and positive associations between PTG and negative versus positive well-being indicators among PLWH. Specifically, the relationship between PTG and positive well-being indicators was more substantial than the link between PTG and negative well-being measures in these patients. Finally, observed high heterogeneity between studies and several measurement problems call for significant modification and improvement of PTG research among PLWH. (Source: Quality of Life Research)
Source: Quality of Life Research - September 14, 2021 Category: Health Management Source Type: research

Author index
(Source: Quality of Life Research)
Source: Quality of Life Research - September 14, 2021 Category: Health Management Source Type: research

Posttraumatic growth and well-being among people living with HIV: A systematic review and meta-analysis in recognition of 40  years of HIV/AIDS
ConclusionsThe present meta-analysis and systematic review revealed expected negative and positive associations between PTG and negative versus positive well-being indicators among PLWH. Specifically, the relationship between PTG and positive well-being indicators was more substantial than the link between PTG and negative well-being measures in these patients. Finally, observed high heterogeneity between studies and several measurement problems call for significant modification and improvement of PTG research among PLWH. (Source: Quality of Life Research)
Source: Quality of Life Research - September 14, 2021 Category: Health Management Source Type: research

Author index
(Source: Quality of Life Research)
Source: Quality of Life Research - September 14, 2021 Category: Health Management Source Type: research

A scoping review on studies about the quality of life of informal caregivers of stroke survivors
ConclusionThere is a need for standardizing the assessment of the QoL of informal caregivers of stroke survivors, as well as for investing in cross-country/cultural studies with robust mixed methods designs to allow a deeper understanding of the experiences of caregivers. Further research, policies, and practices should consider the diversity and complexity of the characteristics influencing QoL, to empower informal caregivers and improve their QoL. (Source: Quality of Life Research)
Source: Quality of Life Research - September 13, 2021 Category: Health Management Source Type: research

Psychometric validation of the EORTC QLQ-HCC18 in patients with previously treated unresectable hepatocellular carcinoma
AbstractTo demonstrate the measurement properties of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Hepatocellular Carcinoma 18-question module (EORTC QLQ-HCC18) within a previously treated, unresectable hepatocellular carcinoma (HCC) clinical trial population that was distinct from the published QLQ-HCC18 validation population. Analyses were conducted using data from BGB-A317-208, an open label, international, clinical trial assessing efficacy and safety of the monoclonal antibody tislelizumab in adult HCC patients. The EORTC Quality of Life Questionnaire Core 30 (EORTC QLQ-C3...
Source: Quality of Life Research - September 13, 2021 Category: Health Management Source Type: research

A scoping review on studies about the quality of life of informal caregivers of stroke survivors
ConclusionThere is a need for standardizing the assessment of the QoL of informal caregivers of stroke survivors, as well as for investing in cross-country/cultural studies with robust mixed methods designs to allow a deeper understanding of the experiences of caregivers. Further research, policies, and practices should consider the diversity and complexity of the characteristics influencing QoL, to empower informal caregivers and improve their QoL. (Source: Quality of Life Research)
Source: Quality of Life Research - September 13, 2021 Category: Health Management Source Type: research

A framework to make PROMs relevant to patients: qualitative study of communication preferences of PROMs
ConclusionPatient attitudes toward the use and communication of PROMs start with the incorporation of patient beliefs, which can facilitate or act as a barrier to engagement. Patients should ideally believe that PROMs are an accurate reflection of personal health state before incorporation into care. Clinicians should endeavor to communicate the purpose of a chosen PROM in line with a patient ’s unique needs and what they feel is most relevant to their own care. Aspects of PROMs results which may be helpful to address include providing context for what scores mean and how they are calculated, and using scores as a wa...
Source: Quality of Life Research - September 11, 2021 Category: Health Management Source Type: research

Measurement invariance of the Seattle Angina Questionnaire in coronary artery disease
ConclusionSAQ-CAN can be used to compare the health status of coronary artery disease patients across population groups and over time. (Source: Quality of Life Research)
Source: Quality of Life Research - September 8, 2021 Category: Health Management Source Type: research

Predictors of pain persistence and disability in high-school students with chronic neck pain at 6-month follow-up
This study aimed to explore the association between psychosocial factors, sleep, and symptoms of central sensitization at baseline and the persistence of neck pain and disability at 6-month follow-up.MethodsA total of 710 adolescents with chronic neck pain were assessed at baseline with an online questionnaire that collected information on sociodemographic data, presence of musculoskeletal pain, pain intensity, physical activity, functional disability, depression, anxiety, stress, quality of sleep, catastrophizing, kinesiophobia, self-efficacy, and symptoms of central sensitization. At 6-month follow-up, adolescents were r...
Source: Quality of Life Research - September 6, 2021 Category: Health Management Source Type: research

Quality of life of parents with children with congenital abnormalities: a systematic review with meta-analysis of assessment methods and levels of quality of life
ConclusionsThis review highlights the relevance of assessing QoL in parents with children with CA and explores the diverse QoL assessment tools described in the literature. Additionally, results indicate a knowledge gap that can help to draw new paths to future research. It is essential to assess QoL as a routine in healthcare providing and to implement strategies that improve it. (Source: Quality of Life Research)
Source: Quality of Life Research - September 5, 2021 Category: Health Management Source Type: research

The Crit coefficient in Mokken scale analysis: a simulation study and an application in quality-of-life research
DiscussionEven in large samples, theCrit coefficient showed limited usefulness for detecting moderate and severe violations of monotonicity. Our findings are relevant to researchers and practitioners who use Mokken scaling for scale and questionnaire construction and revision. (Source: Quality of Life Research)
Source: Quality of Life Research - September 2, 2021 Category: Health Management Source Type: research

The association between nonrestorative sleep and health-related quality of life in Chinese adults: a cross-sectional study
This study aimed to examine the association between nonrestorative sleep and health-related quality of life (HRQL) in Chinese adults.MethodsData were collected through a cross-sectional study of 500 adults in Hong Kong (66.4% female, average age of 39  years). The Short-Form-12 Health Survey version 2 (SF-12v2), Nonrestorative Sleep Scale (NRSS), Pittsburgh Sleep Quality Index, ENRICHD Social Support Instrument, Patient Health Questionnaire, Perceived Stress Scale, and Hospital Anxiety and Depression Scale were administered. Objective sleep para meters were based on participants’ sleep condition over 1 week...
Source: Quality of Life Research - September 1, 2021 Category: Health Management Source Type: research

The handgrip strength and risk of depressive symptoms: a meta-analysis of prospective cohort studies
ConclusionsLower HGS was associated with an increased risk of depressive symptoms. Further studies are needed to confirm these findings and to investigate the sex differences. (Source: Quality of Life Research)
Source: Quality of Life Research - September 1, 2021 Category: Health Management Source Type: research

PROMIS Global Health: Feasibility in home health
ConclusionsThe study confirmed that the PROMIS-10 can be implemented in the HH setting, opening the door for consideration for implementing the PROMIS-10 in post-acute care (PAC) settings. This study is a first step toward establishing an assessment that captures the patient ’s voice and could be reported by the CMS PAC quality reporting programs. (Source: Quality of Life Research)
Source: Quality of Life Research - September 1, 2021 Category: Health Management Source Type: research

Measurement properties of the Boston Carpal Tunnel Questionnaire in subjects with neurophysiological confirmation of carpal tunnel syndrome: a Rasch analysis perspective
ConclusionA log-linear version of the BCTQ, useful as an outcome tool in clinical and trial settings, is proposed. Neurophysiological data lack the ability to resemble changes in clinical status of individuals with CTS. (Source: Quality of Life Research)
Source: Quality of Life Research - August 31, 2021 Category: Health Management Source Type: research

The association between nonrestorative sleep and health-related quality of life in Chinese adults: a cross-sectional study
This study aimed to examine the association between nonrestorative sleep and health-related quality of life (HRQL) in Chinese adults.MethodsData were collected through a cross-sectional study of 500 adults in Hong Kong (66.4% female, average age of 39  years). The Short-Form-12 Health Survey version 2 (SF-12v2), Nonrestorative Sleep Scale (NRSS), Pittsburgh Sleep Quality Index, ENRICHD Social Support Instrument, Patient Health Questionnaire, Perceived Stress Scale, and Hospital Anxiety and Depression Scale were administered. Objective sleep para meters were based on participants’ sleep condition over 1 week...
Source: Quality of Life Research - August 31, 2021 Category: Health Management Source Type: research

The handgrip strength and risk of depressive symptoms: a meta-analysis of prospective cohort studies
ConclusionsLower HGS was associated with an increased risk of depressive symptoms. Further studies are needed to confirm these findings and to investigate the sex differences. (Source: Quality of Life Research)
Source: Quality of Life Research - August 31, 2021 Category: Health Management Source Type: research

A psychometric evaluation of the Functional assessment of cancer therapy —kidney symptom index (FKSI-19) among renal cell carcinoma patients suggesting an alternative two-factor structure
ConclusionThe present study is the first to use psychometric methods for examining the factor structure of the FKSI-19 instrument. The hypothesized four-factor structure of FKSI-19 provided a barely acceptable model fit. The two-factor FKSI-14 structure may be used as an alternative or complement to the four-factor structure when interpreting the FKSI-19 instrument. (Source: Quality of Life Research)
Source: Quality of Life Research - August 31, 2021 Category: Health Management Source Type: research

Health-related quality of life in primary hepatic cancer: a systematic review assessing the methodological properties of instruments and a meta-analysis comparing treatment strategies
ConclusionUsing a standardized methodological assessment, specific HRQoL instruments are recommended for use in patients with hepatocellular and cholangiocellular carcinoma. HRQoL data of patients undergoing treatment of primary liver cancers are sparse and reporting falls short of published standards. Meaningful comparison of established treatment options with regard to HRQoL was impossible indicating the need for future research. (Source: Quality of Life Research)
Source: Quality of Life Research - August 31, 2021 Category: Health Management Source Type: research

The development and initial validation of the Breast Cancer Recurrence instrument (BreastCaRe) —a patient-reported outcome measure for detecting symptoms of recurrence after breast cancer
ConclusionsThe BreastCaRe has good content and structural validity, patient acceptability and measurement invariance. We are preparing to examine the predictive validity of this new instrument. (Source: Quality of Life Research)
Source: Quality of Life Research - August 31, 2021 Category: Health Management Source Type: research

The relationship between emotional intelligence and quality of life in schizophrenia and bipolar I disorder
ConclusionOur findings point to a difference in the interrelation between EI and QoL in patients suffering from SZ and BD, and suggest that they may have different needs to achieve recovery. It will be critical to develop training programs targeting EI in SZ, and to examine their impact on objective QoL in these patients. (Source: Quality of Life Research)
Source: Quality of Life Research - August 31, 2021 Category: Health Management Source Type: research

The impact of idiopathic pulmonary fibrosis on health state utility values: evidence from Australia
ConclusionsOur study has shown that EQ-5D-5L has exhibited discriminatory sensitivity for the study population. We have demonstrated that disease severity and having more than two comorbidities was associated with lower HSUVs in Australians with IPF. Our findings support early diagnosis and appropriate evidence-based treatment to slow or prevent IPF progression; and identification and treatment of associated comorbidities to potentially improve health-related quality of life in people with IPF. (Source: Quality of Life Research)
Source: Quality of Life Research - August 31, 2021 Category: Health Management Source Type: research

Symptom profiles following combat injury and long-term quality of life: a latent class analysis
AbstractPurposeThe purpose of this study was to identify symptom profiles among U.S. military personnel within 1  year after combat injury and assess the relationship between the symptom profiles and long-term quality of life (QoL).MethodsThe study sample consisted of 885 military personnel from the Expeditionary Medical Encounter Database who completed (1) a Post-Deployment Health Assessment (PDHA) within 1  year following combat injury in Iraq or Afghanistan, and (2) a survey for the Wounded Warrior Recovery Project (WWRP), a longitudinal study tracking patient-reported outcomes (e.g., QoL) in injured military ...
Source: Quality of Life Research - August 31, 2021 Category: Health Management Source Type: research

Health-related quality of life in women after colposcopy: results from a longitudinal patient survey
ConclusionsWomen ’s HRQoL did not change over the 12 months post colposcopy, but some subgroups of women were at higher risk of experiencing low HRQoL. These subgroups may benefit from additional support. (Source: Quality of Life Research)
Source: Quality of Life Research - August 31, 2021 Category: Health Management Source Type: research

The influence of frailty syndrome on quality of life in elderly patients with type 2 diabetes
ConclusionsFrailty syndrome occurred in 43 percent of the patients with type 2 diabetes. This has a negative impact on QoL of patients. Depression is more common in patients with the frailty syndrome and diabetes. (Source: Quality of Life Research)
Source: Quality of Life Research - August 31, 2021 Category: Health Management Source Type: research

Psychometric properties of the Dutch-Flemish PROMIS ® pediatric item banks Anxiety and Depressive Symptoms in a general population
ConclusionThe Dutch-Flemish PROMIS pediatric item banks v2.0 Anxiety and Depressive Symptoms, the short forms 8a and CATs are useful to assess and monitor anxiety and depression in a general population. Reference data are presented. (Source: Quality of Life Research)
Source: Quality of Life Research - August 31, 2021 Category: Health Management Source Type: research

PROMIS Global Health: Feasibility in home health
ConclusionsThe study confirmed that the PROMIS-10 can be implemented in the HH setting, opening the door for consideration for implementing the PROMIS-10 in post-acute care (PAC) settings. This study is a first step toward establishing an assessment that captures the patient ’s voice and could be reported by the CMS PAC quality reporting programs. (Source: Quality of Life Research)
Source: Quality of Life Research - August 31, 2021 Category: Health Management Source Type: research

Prospective analysis of disability and quality of life in patients with chronic inflammatory demyelinating polyradiculoneuropathy
AbstractPurposeEven treated chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) continues to pose a significant burden in patients ’ everyday functioning and may continuously affect their quality of life (QoL). The aims of our prospective study were to analyze health-related QoL in CIDP patients during a 1-year follow-up period in real-life settings and to compare QoL changes with changes in disability and with patient impres sion of change.MethodsThe study comprised 59 patients diagnosed with CIDP. SF-36 questionnaire was applied in order to evaluate patients ’ QoL. Inflammatory neuropathy cause a...
Source: Quality of Life Research - August 31, 2021 Category: Health Management Source Type: research

Psychometric assessment of EQ-5D-5L and ReQoL measures in patients with anxiety and depression: construct validity and responsiveness
ConclusionThere is insufficient evidence to recommend the ReQoL-UI over EQ-5D-5L for economic evaluations to capture anxiety severity. However, there may be rationale for recommending the ReQoL-UI over the EQ-5D-5L to capture depression severity given its better construct validity, albeit poorer responsiveness, and if recovery-focussed quality of life relative to condition-specific symptomology is the construct of interest. (Source: Quality of Life Research)
Source: Quality of Life Research - August 31, 2021 Category: Health Management Source Type: research

Association between knee symptoms, change in knee symptoms over 6 –9 years, and SF-6D health state utility among middle-aged Australians
AbstractObjectivesHealth state utilities (HSUs) are an input metric for estimating quality-adjusted life-years (QALY) in cost –utility analyses. Currently, there is a paucity of data on association of knee symptoms with HSUs for middle-aged populations. We aimed to describe the association of knee symptoms and change in knee symptoms with SF-6D HSUs and described the distribution of HSUs against knee symptoms’ severity .MethodsParticipants (36 –49-years) were selected from the third follow-up (completed 2019) of Australian Childhood Determinants of Adult Health study. SF-6D HSUs were generated from the pa...
Source: Quality of Life Research - August 31, 2021 Category: Health Management Source Type: research